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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RUNX1_RUNX2

Z-value: 0.32

Motif logo

Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
ENSG00000159216.14 RUNX1
ENSG00000124813.16 RUNX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX1hg19_v2_chr21_-_36260980_362610110.561.5e-01Click!
RUNX2hg19_v2_chr6_+_45390222_45390298-0.334.2e-01Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_184006611 0.76 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr19_-_51456321 0.67 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr1_+_86889769 0.62 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr19_-_51456344 0.50 ENST00000336334.3
ENST00000593428.1
KLK5
kallikrein-related peptidase 5
chr19_-_6720686 0.48 ENST00000245907.6
C3
complement component 3
chr3_-_189840223 0.47 ENST00000427335.2
LEPREL1
leprecan-like 1
chr5_+_131409476 0.46 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr4_+_89299994 0.39 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_71091786 0.37 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr1_-_235098935 0.37 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr17_-_34417479 0.37 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr19_+_56989609 0.34 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr3_+_145782358 0.34 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr17_-_56494713 0.33 ENST00000407977.2
RNF43
ring finger protein 43
chr1_+_152486950 0.33 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr18_+_21529811 0.32 ENST00000588004.1
LAMA3
laminin, alpha 3
chr19_-_43969796 0.32 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr17_-_29641104 0.31 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr11_+_121447469 0.30 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_41768561 0.30 ENST00000599719.1
ENST00000601309.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr17_-_56494882 0.29 ENST00000584437.1
RNF43
ring finger protein 43
chr19_-_54804173 0.29 ENST00000391744.3
ENST00000251390.3
LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr17_-_56494908 0.29 ENST00000577716.1
RNF43
ring finger protein 43
chr11_-_118134997 0.29 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr1_-_120935894 0.29 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr10_-_105845674 0.29 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr18_+_29027696 0.28 ENST00000257189.4
DSG3
desmoglein 3
chr3_-_49941042 0.28 ENST00000344206.4
ENST00000296474.3
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr9_+_115913222 0.27 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr11_-_1771797 0.27 ENST00000340134.4
IFITM10
interferon induced transmembrane protein 10
chr6_+_160327974 0.27 ENST00000252660.4
MAS1
MAS1 oncogene
chr2_+_220550047 0.26 ENST00000607654.1
ENST00000606673.1
AC009502.4
AC009502.4
chr17_-_34524157 0.25 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr1_-_39395165 0.25 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr20_+_44637526 0.25 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr3_+_189507432 0.25 ENST00000354600.5
TP63
tumor protein p63
chr18_+_61420169 0.25 ENST00000425392.1
ENST00000336429.2
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_118135160 0.24 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr11_+_1860200 0.24 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr4_+_89299885 0.24 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr16_-_72206034 0.23 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr14_+_22966642 0.23 ENST00000390496.1
TRAJ41
T cell receptor alpha joining 41
chr4_+_76481258 0.23 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr15_+_84116106 0.23 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr2_+_37571717 0.22 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr7_+_75028199 0.22 ENST00000437796.1
TRIM73
tripartite motif containing 73
chr17_-_34625719 0.22 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr3_+_98699880 0.22 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr2_+_169658928 0.22 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr17_-_39677971 0.21 ENST00000393976.2
KRT15
keratin 15
chr2_+_169659121 0.21 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr15_+_73976545 0.21 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr19_-_49658387 0.21 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr17_-_7164410 0.21 ENST00000574070.1
CLDN7
claudin 7
chr9_-_130541017 0.21 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr18_+_34124507 0.21 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr19_+_56989485 0.21 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr1_-_24469602 0.20 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr12_-_8693469 0.20 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr17_-_39743139 0.20 ENST00000167586.6
KRT14
keratin 14
chr2_+_37571845 0.20 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr12_-_4754339 0.19 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr19_+_35739280 0.19 ENST00000602122.1
LSR
lipolysis stimulated lipoprotein receptor
chr1_-_209824643 0.19 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr6_-_29013017 0.19 ENST00000377175.1
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr6_+_132891461 0.19 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr3_-_172241250 0.18 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr6_+_31543334 0.18 ENST00000449264.2
TNF
tumor necrosis factor
chr2_+_102615416 0.18 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr19_+_38755203 0.18 ENST00000587090.1
ENST00000454580.3
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr14_-_94854926 0.18 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_+_31496809 0.17 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr20_-_1600642 0.17 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
SIRPB1
RP4-576H24.4
signal-regulatory protein beta 1
Uncharacterized protein
chr15_+_43985725 0.17 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr2_+_113735575 0.17 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr4_+_88896819 0.17 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr22_+_47016277 0.17 ENST00000406902.1
GRAMD4
GRAM domain containing 4
chr11_-_1780261 0.17 ENST00000427721.1
RP11-295K3.1
RP11-295K3.1
chr19_+_29456034 0.17 ENST00000589921.1
LINC00906
long intergenic non-protein coding RNA 906
chr1_-_235098861 0.17 ENST00000458044.1
RP11-443B7.1
RP11-443B7.1
chr18_-_53089723 0.17 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr6_-_29343068 0.17 ENST00000396806.3
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr7_-_141646726 0.17 ENST00000438351.1
ENST00000439991.1
ENST00000551012.2
ENST00000546910.1
CLEC5A
C-type lectin domain family 5, member A
chr1_+_209859510 0.17 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_-_27529726 0.17 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr16_+_85942594 0.17 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr20_+_58713514 0.17 ENST00000432910.1
RP5-1043L13.1
RP5-1043L13.1
chr2_-_217559517 0.17 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr11_+_7626950 0.17 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_151034734 0.17 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr4_+_106816592 0.16 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT
nephronectin
chr1_-_223536679 0.16 ENST00000608996.1
SUSD4
sushi domain containing 4
chr16_+_56965960 0.16 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_-_23825956 0.16 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr16_-_31147020 0.16 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr12_-_86230315 0.16 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr20_-_18038521 0.16 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr19_+_17581253 0.16 ENST00000252595.7
ENST00000598424.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr17_+_16120512 0.16 ENST00000581006.1
ENST00000584797.1
ENST00000498772.2
ENST00000225609.5
ENST00000395844.4
ENST00000477745.1
PIGL
phosphatidylinositol glycan anchor biosynthesis, class L
chr19_+_35739897 0.16 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR
lipolysis stimulated lipoprotein receptor
chr1_+_28261621 0.15 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_+_113779704 0.15 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr20_+_43343886 0.15 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr6_-_33048483 0.15 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr19_+_35739782 0.15 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr7_-_29234802 0.15 ENST00000449801.1
ENST00000409850.1
CPVL
carboxypeptidase, vitellogenic-like
chr11_-_5345582 0.15 ENST00000328813.2
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr2_+_68961934 0.15 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr10_+_129705299 0.15 ENST00000254667.3
PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_-_108464465 0.15 ENST00000525344.1
EXPH5
exophilin 5
chr12_-_71031220 0.15 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr8_-_19540266 0.15 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_68961905 0.15 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_-_235405679 0.15 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr4_+_100737954 0.15 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr21_-_36421535 0.15 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr13_-_28674693 0.15 ENST00000537084.1
ENST00000241453.7
ENST00000380982.4
FLT3
fms-related tyrosine kinase 3
chr10_+_129845823 0.14 ENST00000306042.5
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_+_156030937 0.14 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr12_-_54778471 0.14 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr2_-_89442621 0.14 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr5_+_145316120 0.14 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr2_-_16804320 0.14 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr16_+_82068830 0.14 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr11_-_108464321 0.14 ENST00000265843.4
EXPH5
exophilin 5
chr12_+_19358228 0.14 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr8_-_19540086 0.14 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_-_49258606 0.14 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr16_-_58328870 0.14 ENST00000543437.1
PRSS54
protease, serine, 54
chr7_+_116660246 0.14 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr16_-_58328923 0.14 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr12_-_71031185 0.14 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr4_-_143395551 0.14 ENST00000507861.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_23695680 0.14 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr1_-_25291475 0.14 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr4_-_84035905 0.14 ENST00000311507.4
PLAC8
placenta-specific 8
chr20_+_58630972 0.14 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr5_+_35856951 0.13 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr3_-_55523966 0.13 ENST00000474267.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr15_+_69373184 0.13 ENST00000558147.1
ENST00000440444.1
LINC00277
long intergenic non-protein coding RNA 277
chr2_+_220325441 0.13 ENST00000396688.1
SPEG
SPEG complex locus
chr10_+_60759378 0.13 ENST00000432535.1
LINC00844
long intergenic non-protein coding RNA 844
chr11_+_100862811 0.13 ENST00000303130.2
TMEM133
transmembrane protein 133
chr2_-_235405168 0.13 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chrX_+_48542168 0.13 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr1_+_236557569 0.13 ENST00000334232.4
EDARADD
EDAR-associated death domain
chr5_+_140165876 0.13 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr1_+_28261492 0.13 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr12_-_71003568 0.13 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_-_247921982 0.13 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr20_+_32782375 0.13 ENST00000568305.1
ASIP
agouti signaling protein
chr10_-_13276329 0.13 ENST00000378681.3
ENST00000463405.2
UCMA
upper zone of growth plate and cartilage matrix associated
chr15_+_84115868 0.13 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr11_-_108422926 0.13 ENST00000428840.1
ENST00000526312.1
EXPH5
exophilin 5
chr17_-_37322013 0.13 ENST00000269586.7
ARL5C
ADP-ribosylation factor-like 5C
chr6_-_39197226 0.13 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr2_+_102953608 0.12 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr3_+_98482175 0.12 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr1_+_13910479 0.12 ENST00000509009.1
PDPN
podoplanin
chr11_-_87908600 0.12 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr12_+_49372251 0.12 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr12_-_112819896 0.12 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
chr22_+_25003606 0.12 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chrX_-_77914825 0.12 ENST00000321110.1
ZCCHC5
zinc finger, CCHC domain containing 5
chr3_-_98241358 0.12 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr12_+_29376673 0.12 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chrX_+_135730373 0.12 ENST00000370628.2
CD40LG
CD40 ligand
chr12_+_29376592 0.12 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr17_+_56232494 0.12 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr19_-_49658641 0.12 ENST00000252825.4
HRC
histidine rich calcium binding protein
chr1_+_111772435 0.12 ENST00000524472.1
CHI3L2
chitinase 3-like 2
chr11_-_64885111 0.12 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr20_+_6748311 0.12 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chrX_+_135730297 0.12 ENST00000370629.2
CD40LG
CD40 ligand
chr2_-_105030466 0.12 ENST00000449772.1
AC068535.3
AC068535.3
chr21_+_42733870 0.12 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr1_+_2005425 0.12 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr1_+_202172848 0.12 ENST00000255432.7
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr19_-_7936344 0.12 ENST00000599142.1
CTD-3193O13.9
Protein FLJ22184
chr12_-_14849470 0.12 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr1_+_13910194 0.11 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr12_-_323689 0.11 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr21_-_36421626 0.11 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr8_-_22926623 0.11 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr1_-_217250231 0.11 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr21_-_48024986 0.11 ENST00000291700.4
ENST00000367071.4
S100B
S100 calcium binding protein B
chr1_+_196743912 0.11 ENST00000367425.4
CFHR3
complement factor H-related 3
chr20_+_43343517 0.11 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr20_+_43991668 0.11 ENST00000243918.5
ENST00000426004.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr16_-_10788770 0.11 ENST00000283025.2
TEKT5
tektin 5
chr16_-_28608424 0.11 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_216878305 0.11 ENST00000263268.6
MREG
melanoregulin
chr6_+_29364416 0.11 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr1_-_11714700 0.11 ENST00000354287.4
FBXO2
F-box protein 2
chr2_+_162272605 0.11 ENST00000389554.3
TBR1
T-box, brain, 1
chr1_+_196743943 0.11 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr19_+_55315087 0.11 ENST00000345540.5
ENST00000357494.4
ENST00000396293.1
ENST00000346587.4
ENST00000396289.5
KIR2DL4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr17_+_7533439 0.11 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr1_+_92495528 0.11 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr16_-_28608364 0.11 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.5 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.4 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.5 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.2 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0061346 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0061183 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:1904882 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0051884 regulation of anagen(GO:0051884)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0090346 cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.0 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.0 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0043300 regulation of myeloid leukocyte mediated immunity(GO:0002886) regulation of leukocyte degranulation(GO:0043300)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.0 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.0 GO:0032233 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.0 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.1 GO:0035564 regulation of kidney size(GO:0035564)
0.0 0.0 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:0051023 regulation of immunoglobulin secretion(GO:0051023)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.0 GO:1905204 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.1 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.0 0.0 GO:0072237 metanephric proximal tubule development(GO:0072237)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.0 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.0 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.1 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.0 GO:1904172 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.1 GO:0048021 regulation of melanin biosynthetic process(GO:0048021) regulation of secondary metabolite biosynthetic process(GO:1900376)
0.0 0.0 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.0 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.0 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.0 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.0 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.0 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.3 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0052844 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.0 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.0 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix