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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RUNX3_BCL11A

Z-value: 0.81

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Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
RUNX3
ENSG00000020633.14 RUNX3
BCL11A
ENSG00000119866.16 BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL11Ahg19_v2_chr2_-_60780536_60780541-0.978.3e-05Click!
RUNX3hg19_v2_chr1_-_25256368_25256476-0.753.4e-02Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_33359646 1.52 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr2_+_33359687 1.49 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr16_+_12995614 0.76 ENST00000423335.2
 SHISA9
 shisa family member 9
chr2_-_158300556 0.58 ENST00000264192.3
 CYTIP
 cytohesin 1 interacting protein
chr21_-_36421626 0.54 ENST00000300305.3
 RUNX1
 runt-related transcription factor 1
chr13_-_38172863 0.52 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chr21_-_36421535 0.47 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
 RUNX1
 runt-related transcription factor 1
chr1_+_221051699 0.45 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr1_+_6615241 0.44 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
 TAS1R1
 taste receptor, type 1, member 1
chr8_-_60031762 0.41 ENST00000361421.1
 TOX
 thymocyte selection-associated high mobility group box
chr6_-_169364429 0.40 ENST00000444586.1
 RP3-495K2.3
 RP3-495K2.3
chr5_+_75699149 0.40 ENST00000379730.3
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr3_+_141105705 0.38 ENST00000513258.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr5_+_75699040 0.38 ENST00000274364.6
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr1_-_149889382 0.37 ENST00000369145.1
ENST00000369146.3
 SV2A
 synaptic vesicle glycoprotein 2A
chr3_-_49170405 0.36 ENST00000305544.4
ENST00000494831.1
 LAMB2
 laminin, beta 2 (laminin S)
chr3_+_141105235 0.36 ENST00000503809.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr6_-_31514516 0.34 ENST00000303892.5
ENST00000483251.1
 ATP6V1G2
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr4_-_57976544 0.32 ENST00000295666.4
ENST00000537922.1
 IGFBP7
 insulin-like growth factor binding protein 7
chr10_+_17272608 0.32 ENST00000421459.2
 VIM
 vimentin
chr3_+_141043050 0.32 ENST00000509842.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr1_-_113162040 0.31 ENST00000358039.4
ENST00000369668.2
 ST7L
 suppression of tumorigenicity 7 like
chr3_-_150920979 0.30 ENST00000309180.5
ENST00000480322.1
 GPR171
 G protein-coupled receptor 171
chr17_-_29648761 0.29 ENST00000247270.3
ENST00000462804.2
 EVI2A
 ecotropic viral integration site 2A
chr5_-_111091948 0.29 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr1_-_113161730 0.28 ENST00000544629.1
ENST00000543570.1
ENST00000360743.4
ENST00000490067.1
ENST00000343210.7
ENST00000369666.1
 ST7L
 suppression of tumorigenicity 7 like
chr15_-_93632421 0.28 ENST00000329082.7
 RGMA
 repulsive guidance molecule family member a
chr1_+_164528866 0.28 ENST00000420696.2
 PBX1
 pre-B-cell leukemia homeobox 1
chr15_-_37393406 0.28 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
 MEIS2
 Meis homeobox 2
chr1_+_145727681 0.27 ENST00000417171.1
ENST00000451928.2
 PDZK1
 PDZ domain containing 1
chrX_-_106960285 0.26 ENST00000503515.1
ENST00000372397.2
 TSC22D3
 TSC22 domain family, member 3
chr2_+_136499287 0.26 ENST00000415164.1
 UBXN4
 UBX domain protein 4
chr17_+_38599693 0.26 ENST00000542955.1
ENST00000269593.4
 IGFBP4
 insulin-like growth factor binding protein 4
chr15_-_37392703 0.26 ENST00000382766.2
ENST00000444725.1
 MEIS2
 Meis homeobox 2
chr6_+_144904334 0.25 ENST00000367526.4
 UTRN
 utrophin
chr12_-_4754339 0.25 ENST00000228850.1
 AKAP3
 A kinase (PRKA) anchor protein 3
chr1_-_184006611 0.25 ENST00000546159.1
 COLGALT2
 collagen beta(1-O)galactosyltransferase 2
chr14_+_64680854 0.23 ENST00000458046.2
 SYNE2
 spectrin repeat containing, nuclear envelope 2
chr14_+_51955831 0.23 ENST00000356218.4
 FRMD6
 FERM domain containing 6
chr9_+_75766763 0.22 ENST00000456643.1
ENST00000415424.1
 ANXA1
 annexin A1
chr10_+_17270214 0.22 ENST00000544301.1
 VIM
 vimentin
chr1_-_86043921 0.22 ENST00000535924.2
 DDAH1
 dimethylarginine dimethylaminohydrolase 1
chr3_-_101395936 0.21 ENST00000461821.1
 ZBTB11
 zinc finger and BTB domain containing 11
chr5_+_131993856 0.21 ENST00000304506.3
 IL13
 interleukin 13
chr3_+_50126341 0.21 ENST00000347869.3
ENST00000469838.1
ENST00000404526.2
ENST00000441305.1
 RBM5
 RNA binding motif protein 5
chr7_+_75028199 0.21 ENST00000437796.1
 TRIM73
 tripartite motif containing 73
chr14_+_85996507 0.21 ENST00000554746.1
 FLRT2
 fibronectin leucine rich transmembrane protein 2
chr15_-_43910998 0.21 ENST00000450892.2
 STRC
 stereocilin
chr9_-_130541017 0.21 ENST00000314830.8
 SH2D3C
 SH2 domain containing 3C
chr9_-_123342415 0.20 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
chrX_+_22050546 0.20 ENST00000379374.4
 PHEX
 phosphate regulating endopeptidase homolog, X-linked
chr2_-_175462934 0.20 ENST00000392546.2
ENST00000436221.1
 WIPF1
 WAS/WASL interacting protein family, member 1
chr19_-_17375541 0.19 ENST00000252597.3
 USHBP1
 Usher syndrome 1C binding protein 1
chr16_+_2802623 0.19 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
 SRRM2
 serine/arginine repetitive matrix 2
chr10_+_89420706 0.19 ENST00000427144.2
 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_-_111291587 0.19 ENST00000437167.1
 RGPD6
 RANBP2-like and GRIP domain containing 6
chr11_-_102826434 0.18 ENST00000340273.4
ENST00000260302.3
 MMP13
 matrix metallopeptidase 13 (collagenase 3)
chr12_+_69139886 0.18 ENST00000398004.2
 SLC35E3
 solute carrier family 35, member E3
chrX_+_48542168 0.18 ENST00000376701.4
 WAS
 Wiskott-Aldrich syndrome
chr14_+_85996471 0.18 ENST00000330753.4
 FLRT2
 fibronectin leucine rich transmembrane protein 2
chr3_+_96533413 0.18 ENST00000470610.2
ENST00000389672.5
 EPHA6
 EPH receptor A6
chr15_+_41913690 0.18 ENST00000563576.1
 MGA
 MGA, MAX dimerization protein
chr2_+_228678550 0.18 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chr1_+_39876151 0.17 ENST00000530275.1
 KIAA0754
 KIAA0754
chr20_+_43991668 0.17 ENST00000243918.5
ENST00000426004.1
 SYS1
 SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr11_-_65548265 0.17 ENST00000532090.2
 AP5B1
 adaptor-related protein complex 5, beta 1 subunit
chr11_+_108093559 0.17 ENST00000278616.4
 ATM
 ataxia telangiectasia mutated
chr3_+_98250743 0.17 ENST00000284311.3
 GPR15
 G protein-coupled receptor 15
chr13_-_99910673 0.16 ENST00000397473.2
ENST00000397470.2
 GPR18
 G protein-coupled receptor 18
chr11_-_2323290 0.16 ENST00000381153.3
 C11orf21
 chromosome 11 open reading frame 21
chr12_-_53594227 0.16 ENST00000550743.2
 ITGB7
 integrin, beta 7
chr9_-_20622478 0.16 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_+_75874984 0.16 ENST00000550491.1
 GLIPR1
 GLI pathogenesis-related 1
chr4_+_71091786 0.16 ENST00000317987.5
 FDCSP
 follicular dendritic cell secreted protein
chr22_+_40440804 0.16 ENST00000441751.1
ENST00000301923.9
 TNRC6B
 trinucleotide repeat containing 6B
chr7_-_141646726 0.16 ENST00000438351.1
ENST00000439991.1
ENST00000551012.2
ENST00000546910.1
 CLEC5A
 C-type lectin domain family 5, member A
chr6_-_75912508 0.15 ENST00000416123.2
 COL12A1
 collagen, type XII, alpha 1
chr8_+_27183033 0.15 ENST00000420218.2
 PTK2B
 protein tyrosine kinase 2 beta
chrX_-_40036520 0.15 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
 BCOR
 BCL6 corepressor
chr1_+_17634689 0.15 ENST00000375453.1
ENST00000375448.4
 PADI4
 peptidyl arginine deiminase, type IV
chr3_+_49977440 0.15 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
 RBM6
 RNA binding motif protein 6
chr8_+_27182862 0.15 ENST00000521164.1
ENST00000346049.5
 PTK2B
 protein tyrosine kinase 2 beta
chr18_+_7946941 0.15 ENST00000444013.1
 PTPRM
 protein tyrosine phosphatase, receptor type, M
chrX_+_47441712 0.15 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
 TIMP1
 TIMP metallopeptidase inhibitor 1
chr11_-_67141090 0.14 ENST00000312438.7
 CLCF1
 cardiotrophin-like cytokine factor 1
chr13_+_28527647 0.14 ENST00000567234.1
 LINC00543
 long intergenic non-protein coding RNA 543
chr7_+_120628731 0.14 ENST00000310396.5
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr1_-_235098861 0.14 ENST00000458044.1
 RP11-443B7.1
 RP11-443B7.1
chr8_-_72274467 0.14 ENST00000340726.3
 EYA1
 eyes absent homolog 1 (Drosophila)
chr10_-_65028817 0.14 ENST00000542921.1
 JMJD1C
 jumonji domain containing 1C
chr4_-_57524061 0.14 ENST00000508121.1
 HOPX
 HOP homeobox
chr21_-_31744557 0.14 ENST00000399889.2
 KRTAP13-2
 keratin associated protein 13-2
chr9_-_34048873 0.13 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
 UBAP2
 ubiquitin associated protein 2
chr2_+_68872954 0.13 ENST00000394342.2
 PROKR1
 prokineticin receptor 1
chr17_-_47287928 0.13 ENST00000507680.1
 GNGT2
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr7_+_116660246 0.13 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
 ST7
 suppression of tumorigenicity 7
chr1_+_12524965 0.13 ENST00000471923.1
 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr10_-_14372870 0.13 ENST00000357447.2
 FRMD4A
 FERM domain containing 4A
chr9_+_131799213 0.13 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
 FAM73B
 family with sequence similarity 73, member B
chr12_-_112819896 0.13 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
 HECTD4
 HECT domain containing E3 ubiquitin protein ligase 4
chr3_+_49977490 0.13 ENST00000539992.1
 RBM6
 RNA binding motif protein 6
chr17_-_1531635 0.13 ENST00000571650.1
 SLC43A2
 solute carrier family 43 (amino acid system L transporter), member 2
chr3_+_49977523 0.13 ENST00000422955.1
 RBM6
 RNA binding motif protein 6
chr10_-_65028938 0.12 ENST00000402544.1
 JMJD1C
 jumonji domain containing 1C
chr12_+_79439405 0.12 ENST00000552744.1
 SYT1
 synaptotagmin I
chr13_-_103053946 0.12 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr1_-_168513229 0.12 ENST00000367819.2
 XCL2
 chemokine (C motif) ligand 2
chr17_-_56082455 0.12 ENST00000578794.1
 RP11-159D12.5
 Uncharacterized protein
chr9_-_117853297 0.12 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
 TNC
 tenascin C
chr1_-_161039456 0.12 ENST00000368016.3
 ARHGAP30
 Rho GTPase activating protein 30
chr6_+_30908747 0.12 ENST00000462446.1
ENST00000304311.2
 DPCR1
 diffuse panbronchiolitis critical region 1
chr12_-_71031220 0.12 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr9_+_34652164 0.12 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr8_+_27168988 0.11 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
 PTK2B
 protein tyrosine kinase 2 beta
chr10_-_13276329 0.11 ENST00000378681.3
ENST00000463405.2
 UCMA
 upper zone of growth plate and cartilage matrix associated
chr20_+_43343886 0.11 ENST00000190983.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr22_+_23222886 0.11 ENST00000390319.2
 IGLV3-1
 immunoglobulin lambda variable 3-1
chr20_-_45035198 0.11 ENST00000372176.1
 ELMO2
 engulfment and cell motility 2
chr19_-_17375527 0.11 ENST00000431146.2
ENST00000594190.1
 USHBP1
 Usher syndrome 1C binding protein 1
chr14_-_85996332 0.11 ENST00000380722.1
 RP11-497E19.1
 RP11-497E19.1
chr1_+_110453109 0.11 ENST00000525659.1
 CSF1
 colony stimulating factor 1 (macrophage)
chr20_+_43343517 0.11 ENST00000372865.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr3_-_71179988 0.11 ENST00000491238.1
 FOXP1
 forkhead box P1
chr16_+_31366455 0.11 ENST00000268296.4
 ITGAX
 integrin, alpha X (complement component 3 receptor 4 subunit)
chr19_-_14064114 0.11 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
 PODNL1
 podocan-like 1
chr2_-_71221942 0.11 ENST00000272438.4
 TEX261
 testis expressed 261
chr2_+_136499179 0.11 ENST00000272638.9
 UBXN4
 UBX domain protein 4
chr1_+_117544366 0.11 ENST00000256652.4
ENST00000369470.1
 CD101
 CD101 molecule
chr3_-_71179699 0.10 ENST00000497355.1
 FOXP1
 forkhead box P1
chr19_-_14048804 0.10 ENST00000254320.3
ENST00000586075.1
 PODNL1
 podocan-like 1
chr2_-_55646957 0.10 ENST00000263630.8
 CCDC88A
 coiled-coil domain containing 88A
chr20_+_43343476 0.10 ENST00000372868.2
 WISP2
 WNT1 inducible signaling pathway protein 2
chr2_-_175462456 0.10 ENST00000409891.1
ENST00000410117.1
 WIPF1
 WAS/WASL interacting protein family, member 1
chr19_-_14049184 0.10 ENST00000339560.5
 PODNL1
 podocan-like 1
chr11_-_6426635 0.10 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr5_+_139505520 0.10 ENST00000333305.3
 IGIP
 IgA-inducing protein
chr5_+_133451254 0.10 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
chr8_-_72274095 0.10 ENST00000303824.7
 EYA1
 eyes absent homolog 1 (Drosophila)
chr12_-_71031185 0.10 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr17_+_7239821 0.10 ENST00000158762.3
ENST00000570457.2
 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr9_-_130517522 0.10 ENST00000373274.3
ENST00000420366.1
 SH2D3C
 SH2 domain containing 3C
chr17_-_1532106 0.10 ENST00000301335.5
ENST00000382147.4
 SLC43A2
 solute carrier family 43 (amino acid system L transporter), member 2
chr20_+_31595406 0.10 ENST00000170150.3
 BPIFB2
 BPI fold containing family B, member 2
chr2_-_55647057 0.10 ENST00000436346.1
 CCDC88A
 coiled-coil domain containing 88A
chr8_-_116681221 0.10 ENST00000395715.3
 TRPS1
 trichorhinophalangeal syndrome I
chr13_-_28674693 0.10 ENST00000537084.1
ENST00000241453.7
ENST00000380982.4
 FLT3
 fms-related tyrosine kinase 3
chr4_+_78783674 0.10 ENST00000315567.8
 MRPL1
 mitochondrial ribosomal protein L1
chr1_+_111772435 0.10 ENST00000524472.1
 CHI3L2
 chitinase 3-like 2
chr16_-_89785777 0.09 ENST00000561976.1
 VPS9D1
 VPS9 domain containing 1
chr20_-_45035223 0.09 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
 ELMO2
 engulfment and cell motility 2
chr11_+_75428857 0.09 ENST00000198801.5
 MOGAT2
 monoacylglycerol O-acyltransferase 2
chr16_-_10652993 0.09 ENST00000536829.1
 EMP2
 epithelial membrane protein 2
chr5_+_156607829 0.09 ENST00000422843.3
 ITK
 IL2-inducible T-cell kinase
chr1_-_227505289 0.09 ENST00000366765.3
 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
chr3_-_147124547 0.09 ENST00000491672.1
ENST00000383075.3
 ZIC4
 Zic family member 4
chr2_-_220083076 0.09 ENST00000295750.4
 ABCB6
 ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr6_+_27925019 0.09 ENST00000244623.1
 OR2B6
 olfactory receptor, family 2, subfamily B, member 6
chr5_-_159546396 0.09 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
 PWWP2A
 PWWP domain containing 2A
chr17_-_39183452 0.09 ENST00000361883.5
 KRTAP1-5
 keratin associated protein 1-5
chr1_-_182641367 0.09 ENST00000508450.1
 RGS8
 regulator of G-protein signaling 8
chr11_+_22696314 0.08 ENST00000532398.1
ENST00000433790.1
 GAS2
 growth arrest-specific 2
chr9_+_118916082 0.08 ENST00000328252.3
 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
chr11_-_108093329 0.08 ENST00000278612.8
 NPAT
 nuclear protein, ataxia-telangiectasia locus
chr11_-_5345582 0.08 ENST00000328813.2
 OR51B2
 olfactory receptor, family 51, subfamily B, member 2
chr7_+_18535346 0.08 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
 HDAC9
 histone deacetylase 9
chr5_-_127674883 0.08 ENST00000507835.1
 FBN2
 fibrillin 2
chr6_+_74405501 0.08 ENST00000437994.2
ENST00000422508.2
 CD109
 CD109 molecule
chr6_+_86159821 0.08 ENST00000369651.3
 NT5E
 5'-nucleotidase, ecto (CD73)
chr12_+_120884222 0.08 ENST00000551765.1
ENST00000229384.5
 GATC
 glutamyl-tRNA(Gln) amidotransferase, subunit C
chr18_-_77276057 0.08 ENST00000597412.1
 AC018445.1
 Uncharacterized protein
chrX_-_118739835 0.08 ENST00000542113.1
ENST00000304449.5
 NKRF
 NFKB repressing factor
chr1_-_179112173 0.08 ENST00000408940.3
ENST00000504405.1
 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
chr6_+_167704838 0.08 ENST00000366829.2
 UNC93A
 unc-93 homolog A (C. elegans)
chr19_-_44285401 0.08 ENST00000262888.3
 KCNN4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr9_-_139642968 0.08 ENST00000341206.4
 LCN6
 lipocalin 6
chr2_-_18741882 0.08 ENST00000381249.3
 RDH14
 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr17_-_4545170 0.08 ENST00000576394.1
ENST00000574640.1
 ALOX15
 arachidonate 15-lipoxygenase
chr2_-_217559517 0.08 ENST00000449583.1
 IGFBP5
 insulin-like growth factor binding protein 5
chr11_+_196738 0.08 ENST00000325113.4
ENST00000342593.5
 ODF3
 outer dense fiber of sperm tails 3
chrX_-_19688475 0.08 ENST00000541422.1
 SH3KBP1
 SH3-domain kinase binding protein 1
chr1_+_168545711 0.08 ENST00000367818.3
 XCL1
 chemokine (C motif) ligand 1
chr2_+_202316392 0.07 ENST00000194530.3
ENST00000392249.2
 STRADB
 STE20-related kinase adaptor beta
chr1_-_92951607 0.07 ENST00000427103.1
 GFI1
 growth factor independent 1 transcription repressor
chr3_+_40518599 0.07 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
 ZNF619
 zinc finger protein 619
chr1_-_161039753 0.07 ENST00000368015.1
 ARHGAP30
 Rho GTPase activating protein 30
chr16_-_2837949 0.07 ENST00000570702.1
 PRSS33
 protease, serine, 33
chr12_-_8693469 0.07 ENST00000545274.1
ENST00000446457.2
 CLEC4E
 C-type lectin domain family 4, member E
chr17_+_19281034 0.07 ENST00000308406.5
ENST00000299612.7
 MAPK7
 mitogen-activated protein kinase 7
chr2_-_68052694 0.07 ENST00000457448.1
 AC010987.6
 AC010987.6
chr14_-_35183886 0.07 ENST00000298159.6
 CFL2
 cofilin 2 (muscle)
chr19_-_44124019 0.07 ENST00000300811.3
 ZNF428
 zinc finger protein 428
chr13_-_62001982 0.07 ENST00000409186.1
 PCDH20
 protocadherin 20
chr8_-_19540266 0.07 ENST00000311540.4
 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_-_19262486 0.07 ENST00000250024.4
 E2F8
 E2F transcription factor 8
chr6_+_12290586 0.07 ENST00000379375.5
 EDN1
 endothelin 1
chr11_-_35287243 0.07 ENST00000464522.2
 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_+_60995849 0.07 ENST00000537932.1
 PGA4
 pepsinogen 4, group I (pepsinogen A)
chr22_-_30642782 0.07 ENST00000249075.3
 LIF
 leukemia inhibitory factor
chr1_-_161039647 0.07 ENST00000368013.3
 ARHGAP30
 Rho GTPase activating protein 30
chr8_-_19540086 0.07 ENST00000332246.6
 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.5 GO:1990523 bone regeneration(GO:1990523)
0.1 0.4 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 0.2 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.1 GO:0007566 embryo implantation(GO:0007566)
0.1 0.2 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.3 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:1903971 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.0 0.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 4.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling