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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SMAD2

Z-value: 0.64

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Transcription factors associated with SMAD2

Gene Symbol Gene ID Gene Info
SMAD2
ENSG00000175387.11 SMAD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD2hg19_v2_chr18_-_45457192_45457278-0.492.2e-01Click!

Activity profile of SMAD2 motif

Sorted Z-values of SMAD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_159141397 1.02 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chr12_+_53443963 0.59 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr21_+_47401650 0.48 ENST00000361866.3
 COL6A1
 collagen, type VI, alpha 1
chr10_+_72972281 0.43 ENST00000335350.6
 UNC5B
 unc-5 homolog B (C. elegans)
chr22_-_24641027 0.41 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
 GGT5
 gamma-glutamyltransferase 5
chr5_-_150521192 0.37 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr17_-_15165854 0.35 ENST00000395936.1
ENST00000395938.2
 PMP22
 peripheral myelin protein 22
chrX_-_107018969 0.34 ENST00000372383.4
 TSC22D3
 TSC22 domain family, member 3
chr6_-_152489484 0.31 ENST00000354674.4
ENST00000539504.1
 SYNE1
 spectrin repeat containing, nuclear envelope 1
chr12_+_53443680 0.30 ENST00000314250.6
ENST00000451358.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr16_-_3355645 0.30 ENST00000396862.1
ENST00000573608.1
 TIGD7
 tigger transposable element derived 7
chr11_+_71238313 0.26 ENST00000398536.4
 KRTAP5-7
 keratin associated protein 5-7
chr19_+_10527449 0.25 ENST00000592685.1
ENST00000380702.2
 PDE4A
 phosphodiesterase 4A, cAMP-specific
chr15_-_82338460 0.24 ENST00000558133.1
ENST00000329713.4
 MEX3B
 mex-3 RNA binding family member B
chr11_-_5462744 0.23 ENST00000380211.1
 OR51I1
 olfactory receptor, family 51, subfamily I, member 1
chr3_+_194406603 0.23 ENST00000329759.4
 FAM43A
 family with sequence similarity 43, member A
chr12_-_29936731 0.23 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
 TMTC1
 transmembrane and tetratricopeptide repeat containing 1
chr1_+_185703513 0.23 ENST00000271588.4
ENST00000367492.2
 HMCN1
 hemicentin 1
chr8_-_95907423 0.22 ENST00000396133.3
ENST00000308108.4
 CCNE2
 cyclin E2
chr20_+_34680620 0.19 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
chr7_-_100493744 0.18 ENST00000428317.1
ENST00000441605.1
 ACHE
 acetylcholinesterase (Yt blood group)
chr16_+_31483374 0.18 ENST00000394863.3
 TGFB1I1
 transforming growth factor beta 1 induced transcript 1
chr4_-_39640513 0.18 ENST00000511809.1
ENST00000505729.1
 SMIM14
 small integral membrane protein 14
chr16_-_54320675 0.18 ENST00000329734.3
 IRX3
 iroquois homeobox 3
chr19_-_51587502 0.17 ENST00000156499.2
ENST00000391802.1
 KLK14
 kallikrein-related peptidase 14
chr16_-_17564738 0.17 ENST00000261381.6
 XYLT1
 xylosyltransferase I
chr4_-_39640700 0.17 ENST00000295958.5
 SMIM14
 small integral membrane protein 14
chr7_-_100493482 0.16 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
 ACHE
 acetylcholinesterase (Yt blood group)
chr20_-_56284816 0.16 ENST00000395819.3
ENST00000341744.3
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chrX_-_107019181 0.16 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
 TSC22D3
 TSC22 domain family, member 3
chr3_-_88108212 0.15 ENST00000482016.1
 CGGBP1
 CGG triplet repeat binding protein 1
chr10_-_14372870 0.15 ENST00000357447.2
 FRMD4A
 FERM domain containing 4A
chr5_+_140762268 0.14 ENST00000518325.1
 PCDHGA7
 protocadherin gamma subfamily A, 7
chr6_+_41010293 0.13 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
 TSPO2
 translocator protein 2
chr8_-_91657740 0.13 ENST00000422900.1
 TMEM64
 transmembrane protein 64
chr21_+_46117087 0.13 ENST00000400365.3
 KRTAP10-12
 keratin associated protein 10-12
chr3_+_197518100 0.13 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
 LRCH3
 leucine-rich repeats and calponin homology (CH) domain containing 3
chr8_+_95907993 0.13 ENST00000523378.1
 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr15_+_75498739 0.12 ENST00000565074.1
 C15orf39
 chromosome 15 open reading frame 39
chr6_+_6588902 0.12 ENST00000230568.4
 LY86
 lymphocyte antigen 86
chr3_-_15374659 0.12 ENST00000426925.1
 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
chr4_-_113437328 0.12 ENST00000313341.3
 NEUROG2
 neurogenin 2
chr6_+_132873832 0.11 ENST00000275200.1
 TAAR8
 trace amine associated receptor 8
chr20_-_36889127 0.11 ENST00000279024.4
 KIAA1755
 KIAA1755
chr6_+_39760129 0.11 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chrX_-_151143140 0.11 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
 GABRE
 gamma-aminobutyric acid (GABA) A receptor, epsilon
chrX_-_48328631 0.11 ENST00000429543.1
ENST00000317669.5
 SLC38A5
 solute carrier family 38, member 5
chr1_+_33722080 0.11 ENST00000483388.1
ENST00000539719.1
 ZNF362
 zinc finger protein 362
chr6_+_39760783 0.10 ENST00000398904.2
ENST00000538976.1
 DAAM2
 dishevelled associated activator of morphogenesis 2
chrX_-_48328551 0.10 ENST00000376876.3
 SLC38A5
 solute carrier family 38, member 5
chr6_+_147525541 0.10 ENST00000367481.3
ENST00000546097.1
 STXBP5
 syntaxin binding protein 5 (tomosyn)
chr1_-_211752073 0.10 ENST00000367001.4
 SLC30A1
 solute carrier family 30 (zinc transporter), member 1
chr3_+_50316458 0.10 ENST00000316436.3
 LSMEM2
 leucine-rich single-pass membrane protein 2
chr1_-_155271213 0.10 ENST00000342741.4
 PKLR
 pyruvate kinase, liver and RBC
chr4_-_5890145 0.10 ENST00000397890.2
 CRMP1
 collapsin response mediator protein 1
chr3_-_51937331 0.10 ENST00000310914.5
 IQCF1
 IQ motif containing F1
chr7_-_105517021 0.10 ENST00000318724.4
ENST00000419735.3
 ATXN7L1
 ataxin 7-like 1
chr17_+_68165657 0.10 ENST00000243457.3
 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
chr9_+_140145713 0.10 ENST00000388931.3
ENST00000412566.1
 C9orf173
 chromosome 9 open reading frame 173
chr11_-_33913708 0.09 ENST00000257818.2
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr22_-_31885514 0.09 ENST00000397525.1
 EIF4ENIF1
 eukaryotic translation initiation factor 4E nuclear import factor 1
chr16_+_53164833 0.09 ENST00000564845.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr7_-_105516923 0.09 ENST00000478915.1
 ATXN7L1
 ataxin 7-like 1
chrX_-_154688276 0.09 ENST00000369445.2
 F8A3
 coagulation factor VIII-associated 3
chr3_-_88108192 0.09 ENST00000309534.6
 CGGBP1
 CGG triplet repeat binding protein 1
chr11_-_65150103 0.09 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
 SLC25A45
 solute carrier family 25, member 45
chr6_-_159466042 0.09 ENST00000338313.5
 TAGAP
 T-cell activation RhoGTPase activating protein
chr11_-_75380165 0.09 ENST00000304771.3
 MAP6
 microtubule-associated protein 6
chr3_+_88108381 0.09 ENST00000473136.1
 RP11-159G9.5
 Uncharacterized protein
chr20_+_43343517 0.08 ENST00000372865.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr12_-_89918522 0.08 ENST00000529983.2
 GALNT4
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr11_-_75379612 0.08 ENST00000526740.1
 MAP6
 microtubule-associated protein 6
chr1_+_36772691 0.08 ENST00000312808.4
ENST00000505871.1
 SH3D21
 SH3 domain containing 21
chr9_+_125273081 0.08 ENST00000335302.5
 OR1J2
 olfactory receptor, family 1, subfamily J, member 2
chr20_+_43343886 0.08 ENST00000190983.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr20_+_43343476 0.08 ENST00000372868.2
 WISP2
 WNT1 inducible signaling pathway protein 2
chr13_-_80915059 0.08 ENST00000377104.3
 SPRY2
 sprouty homolog 2 (Drosophila)
chr1_-_1243252 0.08 ENST00000353662.3
 ACAP3
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr1_-_201915590 0.07 ENST00000367288.4
 LMOD1
 leiomodin 1 (smooth muscle)
chr16_+_2198604 0.07 ENST00000210187.6
 RAB26
 RAB26, member RAS oncogene family
chr13_+_96743093 0.07 ENST00000376705.2
 HS6ST3
 heparan sulfate 6-O-sulfotransferase 3
chr22_+_23213658 0.07 ENST00000390318.2
 IGLV4-3
 immunoglobulin lambda variable 4-3
chr19_-_46288917 0.07 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
 DMWD
AC011530.4
 dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr12_-_108991812 0.07 ENST00000392806.3
ENST00000547567.1
 TMEM119
 transmembrane protein 119
chr1_-_59249732 0.07 ENST00000371222.2
 JUN
 jun proto-oncogene
chr2_+_5832799 0.07 ENST00000322002.3
 SOX11
 SRY (sex determining region Y)-box 11
chr5_+_14143728 0.07 ENST00000344204.4
ENST00000537187.1
 TRIO
 trio Rho guanine nucleotide exchange factor
chr19_+_49977818 0.07 ENST00000594009.1
ENST00000595510.1
 FLT3LG
 fms-related tyrosine kinase 3 ligand
chr3_-_71179699 0.07 ENST00000497355.1
 FOXP1
 forkhead box P1
chr1_-_207119738 0.07 ENST00000356495.4
 PIGR
 polymeric immunoglobulin receptor
chr19_+_15619299 0.07 ENST00000269703.3
 CYP4F22
 cytochrome P450, family 4, subfamily F, polypeptide 22
chr9_+_33524240 0.06 ENST00000290943.6
 ANKRD18B
 ankyrin repeat domain 18B
chr9_-_137809718 0.06 ENST00000371806.3
 FCN1
 ficolin (collagen/fibrinogen domain containing) 1
chr22_-_38851205 0.06 ENST00000303592.3
 KCNJ4
 potassium inwardly-rectifying channel, subfamily J, member 4
chr3_+_40547483 0.06 ENST00000420891.1
ENST00000314529.6
ENST00000418905.1
 ZNF620
 zinc finger protein 620
chrX_+_153029633 0.06 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
 PLXNB3
 plexin B3
chr3_-_71179988 0.06 ENST00000491238.1
 FOXP1
 forkhead box P1
chr11_+_2923423 0.06 ENST00000312221.5
 SLC22A18
 solute carrier family 22, member 18
chr16_+_57702099 0.06 ENST00000333493.4
ENST00000327655.6
 GPR97
 G protein-coupled receptor 97
chr9_-_73029540 0.06 ENST00000377126.2
 KLF9
 Kruppel-like factor 9
chr20_+_44098385 0.06 ENST00000217425.5
ENST00000339946.3
 WFDC2
 WAP four-disulfide core domain 2
chr11_-_65149422 0.06 ENST00000526432.1
ENST00000527174.1
 SLC25A45
 solute carrier family 25, member 45
chr7_+_155250824 0.06 ENST00000297375.4
 EN2
 engrailed homeobox 2
chr14_+_62162258 0.06 ENST00000337138.4
ENST00000394997.1
 HIF1A
 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr6_-_134861089 0.06 ENST00000606039.1
 RP11-557H15.4
 RP11-557H15.4
chr8_-_142377367 0.06 ENST00000377741.3
 GPR20
 G protein-coupled receptor 20
chr22_+_22764088 0.06 ENST00000390299.2
 IGLV1-40
 immunoglobulin lambda variable 1-40
chr21_+_46066331 0.06 ENST00000334670.8
 KRTAP10-11
 keratin associated protein 10-11
chr20_+_42143053 0.06 ENST00000373135.3
ENST00000444063.1
 L3MBTL1
 l(3)mbt-like 1 (Drosophila)
chr4_-_114682597 0.06 ENST00000394524.3
 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
chr1_+_36771946 0.06 ENST00000373139.2
ENST00000453908.2
ENST00000426732.2
 SH3D21
 SH3 domain containing 21
chr6_+_108487245 0.06 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chr11_+_74204395 0.06 ENST00000526036.1
 AP001372.2
 AP001372.2
chr3_+_52529346 0.06 ENST00000321725.6
 STAB1
 stabilin 1
chr19_-_44285401 0.06 ENST00000262888.3
 KCNN4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_+_34482630 0.05 ENST00000538621.1
 PACSIN1
 protein kinase C and casein kinase substrate in neurons 1
chr11_+_74951948 0.05 ENST00000562197.2
 TPBGL
 trophoblast glycoprotein-like
chr10_-_75193308 0.05 ENST00000299432.2
 MSS51
 MSS51 mitochondrial translational activator
chr19_+_16999654 0.05 ENST00000248076.3
 F2RL3
 coagulation factor II (thrombin) receptor-like 3
chr1_-_160040038 0.05 ENST00000368089.3
 KCNJ10
 potassium inwardly-rectifying channel, subfamily J, member 10
chr17_-_1389419 0.05 ENST00000575158.1
 MYO1C
 myosin IC
chr17_-_58469687 0.05 ENST00000590133.1
 USP32
 ubiquitin specific peptidase 32
chr20_+_44098346 0.05 ENST00000372676.3
 WFDC2
 WAP four-disulfide core domain 2
chr1_+_93913665 0.05 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
 FNBP1L
 formin binding protein 1-like
chr8_-_130587254 0.05 ENST00000523151.1
 CCDC26
 coiled-coil domain containing 26
chr20_+_30598231 0.05 ENST00000300415.8
ENST00000262659.8
 CCM2L
 cerebral cavernous malformation 2-like
chr16_-_87417351 0.05 ENST00000311635.7
 FBXO31
 F-box protein 31
chr5_+_70751442 0.05 ENST00000358731.4
ENST00000380675.2
 BDP1
 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr13_-_96705624 0.05 ENST00000376747.3
ENST00000376712.4
ENST00000397618.3
ENST00000376714.3
 UGGT2
 UDP-glucose glycoprotein glucosyltransferase 2
chr11_-_119211525 0.05 ENST00000528368.1
 C1QTNF5
 C1q and tumor necrosis factor related protein 5
chr6_+_31730773 0.04 ENST00000415669.2
ENST00000425424.1
 SAPCD1
 suppressor APC domain containing 1
chr4_+_7045042 0.04 ENST00000310074.7
ENST00000512388.1
 TADA2B
 transcriptional adaptor 2B
chr12_+_110338323 0.04 ENST00000312777.5
ENST00000536408.2
 TCHP
 trichoplein, keratin filament binding
chr17_-_10017864 0.04 ENST00000323816.4
 GAS7
 growth arrest-specific 7
chr16_+_58059470 0.04 ENST00000219271.3
 MMP15
 matrix metallopeptidase 15 (membrane-inserted)
chr3_-_62359180 0.04 ENST00000283268.3
 FEZF2
 FEZ family zinc finger 2
chrX_-_100183894 0.04 ENST00000328526.5
ENST00000372956.2
 XKRX
 XK, Kell blood group complex subunit-related, X-linked
chr14_-_106494587 0.04 ENST00000390597.2
 IGHV2-5
 immunoglobulin heavy variable 2-5
chr3_+_195447738 0.04 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
 MUC20
 mucin 20, cell surface associated
chr16_+_2286726 0.04 ENST00000382437.4
ENST00000569184.1
 DNASE1L2
 deoxyribonuclease I-like 2
chr1_-_149908710 0.04 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
 MTMR11
 myotubularin related protein 11
chr4_-_140477353 0.04 ENST00000406354.1
ENST00000506866.2
 SETD7
 SET domain containing (lysine methyltransferase) 7
chr1_-_153508460 0.04 ENST00000462776.2
 S100A6
 S100 calcium binding protein A6
chrX_-_99987088 0.04 ENST00000372981.1
ENST00000263033.5
 SYTL4
 synaptotagmin-like 4
chr17_-_3571934 0.04 ENST00000225525.3
 TAX1BP3
 Tax1 (human T-cell leukemia virus type I) binding protein 3
chr4_-_103748880 0.04 ENST00000453744.2
ENST00000349311.8
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr16_+_28889703 0.04 ENST00000357084.3
 ATP2A1
 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr1_+_15783222 0.04 ENST00000359621.4
 CELA2A
 chymotrypsin-like elastase family, member 2A
chrX_-_47489244 0.04 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
 CFP
 complement factor properdin
chr12_-_120554534 0.04 ENST00000538903.1
ENST00000534951.1
 RAB35
 RAB35, member RAS oncogene family
chr6_+_99282570 0.03 ENST00000328345.5
 POU3F2
 POU class 3 homeobox 2
chr9_-_130829588 0.03 ENST00000373078.4
 NAIF1
 nuclear apoptosis inducing factor 1
chr1_+_156163880 0.03 ENST00000359511.4
ENST00000423538.2
 SLC25A44
 solute carrier family 25, member 44
chr9_+_5890802 0.03 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
 MLANA
 melan-A
chr1_+_160097462 0.03 ENST00000447527.1
 ATP1A2
 ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr21_-_36259445 0.03 ENST00000399240.1
 RUNX1
 runt-related transcription factor 1
chr14_+_31343747 0.03 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
 COCH
 cochlin
chr9_+_34990219 0.03 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
 DNAJB5
 DnaJ (Hsp40) homolog, subfamily B, member 5
chr1_-_149908217 0.03 ENST00000369140.3
 MTMR11
 myotubularin related protein 11
chr15_+_74610894 0.03 ENST00000558821.1
ENST00000268082.4
 CCDC33
 coiled-coil domain containing 33
chr4_-_103749179 0.03 ENST00000502690.1
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr19_-_43383819 0.03 ENST00000312439.6
ENST00000403380.3
 PSG1
 pregnancy specific beta-1-glycoprotein 1
chr13_+_114238997 0.03 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr2_-_220173685 0.03 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
 PTPRN
 protein tyrosine phosphatase, receptor type, N
chr20_-_25062767 0.03 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
 VSX1
 visual system homeobox 1
chr9_+_103790991 0.03 ENST00000374874.3
 LPPR1
 Lipid phosphate phosphatase-related protein type 1
chr22_+_22735135 0.03 ENST00000390297.2
 IGLV1-44
 immunoglobulin lambda variable 1-44
chr5_+_139493665 0.03 ENST00000331327.3
 PURA
 purine-rich element binding protein A
chr12_-_10251539 0.03 ENST00000420265.2
 CLEC1A
 C-type lectin domain family 1, member A
chr4_-_164534657 0.03 ENST00000339875.5
 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_-_159466136 0.03 ENST00000367066.3
ENST00000326965.6
 TAGAP
 T-cell activation RhoGTPase activating protein
chr17_+_30593195 0.03 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
 RHBDL3
 rhomboid, veinlet-like 3 (Drosophila)
chr12_-_47473557 0.03 ENST00000321382.3
 AMIGO2
 adhesion molecule with Ig-like domain 2
chr17_-_60142609 0.03 ENST00000397786.2
 MED13
 mediator complex subunit 13
chr1_+_160085501 0.03 ENST00000361216.3
 ATP1A2
 ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr20_+_36888551 0.03 ENST00000418004.1
ENST00000451435.1
 BPI
 bactericidal/permeability-increasing protein
chr19_+_51645556 0.03 ENST00000601682.1
ENST00000317643.6
ENST00000305628.7
ENST00000600577.1
 SIGLEC7
 sialic acid binding Ig-like lectin 7
chr21_-_38639813 0.02 ENST00000309117.6
ENST00000398998.1
 DSCR3
 Down syndrome critical region gene 3
chrX_+_48660287 0.02 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
 HDAC6
 histone deacetylase 6
chr2_+_168725458 0.02 ENST00000392690.3
 B3GALT1
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr21_+_45993606 0.02 ENST00000400374.3
 KRTAP10-4
 keratin associated protein 10-4
chr9_-_34523027 0.02 ENST00000399775.2
 ENHO
 energy homeostasis associated
chr12_-_56583243 0.02 ENST00000550164.1
 SMARCC2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr22_+_31518938 0.02 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J
 inositol polyphosphate-5-phosphatase J
chr6_+_6588316 0.02 ENST00000379953.2
 LY86
 lymphocyte antigen 86
chr19_-_42636543 0.02 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
 POU2F2
 POU class 2 homeobox 2
chr12_-_47473425 0.02 ENST00000550413.1
 AMIGO2
 adhesion molecule with Ig-like domain 2
chr20_-_33413416 0.02 ENST00000359003.2
 NCOA6
 nuclear receptor coactivator 6
chr3_+_123813509 0.02 ENST00000460856.1
ENST00000240874.3
 KALRN
 kalirin, RhoGEF kinase
chr16_+_28889801 0.02 ENST00000395503.4
 ATP2A1
 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr7_-_130080818 0.02 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
 CEP41
 centrosomal protein 41kDa
chr12_-_47473642 0.02 ENST00000266581.4
 AMIGO2
 adhesion molecule with Ig-like domain 2
chr16_-_67997947 0.02 ENST00000537830.2
 SLC12A4
 solute carrier family 12 (potassium/chloride transporter), member 4
chr5_+_64064748 0.02 ENST00000381070.3
ENST00000508024.1
 CWC27
 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr6_+_30689401 0.02 ENST00000396389.1
ENST00000396384.1
 TUBB
 tubulin, beta class I
chr11_+_117857063 0.02 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
 IL10RA
 interleukin 10 receptor, alpha
chr7_+_69064566 0.02 ENST00000403018.2
 AUTS2
 autism susceptibility candidate 2
chr12_+_129178451 0.02 ENST00000537538.1
 TMEM132C
 transmembrane protein 132C
chr12_+_68042495 0.02 ENST00000344096.3
 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr4_+_93225550 0.02 ENST00000282020.4
 GRID2
 glutamate receptor, ionotropic, delta 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.0 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.0 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.0 GO:0045160 myosin I complex(GO:0045160)
0.0 0.4 GO:0043218 compact myelin(GO:0043218)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis