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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SMAD3

Z-value: 0.74

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Transcription factors associated with SMAD3

Gene Symbol Gene ID Gene Info
SMAD3
ENSG00000166949.11 SMAD3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD3hg19_v2_chr15_+_67358163_673581920.521.8e-01Click!

Activity profile of SMAD3 motif

Sorted Z-values of SMAD3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_209602771 0.93 ENST00000440276.1
 MIR205HG
 MIR205 host gene (non-protein coding)
chr20_+_58251716 0.62 ENST00000355648.4
 PHACTR3
 phosphatase and actin regulator 3
chr5_+_52776228 0.51 ENST00000256759.3
 FST
 follistatin
chr4_-_90759440 0.43 ENST00000336904.3
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_11688447 0.36 ENST00000590420.1
 ACP5
 acid phosphatase 5, tartrate resistant
chr6_-_11807277 0.27 ENST00000379415.2
 ADTRP
 androgen-dependent TFPI-regulating protein
chr6_-_27114577 0.25 ENST00000356950.1
ENST00000396891.4
 HIST1H2BK
 histone cluster 1, H2bk
chr18_+_29598335 0.23 ENST00000217740.3
 RNF125
 ring finger protein 125, E3 ubiquitin protein ligase
chr1_+_153388993 0.23 ENST00000368729.4
 S100A7A
 S100 calcium binding protein A7A
chr6_+_30850697 0.21 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr19_-_11688500 0.21 ENST00000433365.2
 ACP5
 acid phosphatase 5, tartrate resistant
chr6_-_27100529 0.20 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
 HIST1H2BJ
 histone cluster 1, H2bj
chr6_+_26124373 0.20 ENST00000377791.2
ENST00000602637.1
 HIST1H2AC
 histone cluster 1, H2ac
chr6_+_27791862 0.20 ENST00000355057.1
 HIST1H4J
 histone cluster 1, H4j
chr6_-_133119668 0.19 ENST00000275227.4
ENST00000538764.1
 SLC18B1
 solute carrier family 18, subfamily B, member 1
chr17_+_30813576 0.18 ENST00000313401.3
 CDK5R1
 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_-_43487780 0.17 ENST00000532038.1
ENST00000528677.1
 ARHGAP27
 Rho GTPase activating protein 27
chr20_-_23030296 0.16 ENST00000377103.2
 THBD
 thrombomodulin
chr20_-_6103666 0.16 ENST00000536936.1
 FERMT1
 fermitin family member 1
chr7_+_139529040 0.15 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
 TBXAS1
 thromboxane A synthase 1 (platelet)
chr6_+_47666275 0.15 ENST00000327753.3
ENST00000283303.2
 GPR115
 G protein-coupled receptor 115
chr6_-_27775694 0.15 ENST00000377401.2
 HIST1H2BL
 histone cluster 1, H2bl
chr16_+_618837 0.15 ENST00000409439.2
 PIGQ
 phosphatidylinositol glycan anchor biosynthesis, class Q
chr1_-_9189229 0.15 ENST00000377411.4
 GPR157
 G protein-coupled receptor 157
chr7_+_139528952 0.14 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
 TBXAS1
 thromboxane A synthase 1 (platelet)
chr20_-_43280361 0.14 ENST00000372874.4
 ADA
 adenosine deaminase
chr17_-_73874654 0.14 ENST00000254816.2
 TRIM47
 tripartite motif containing 47
chr15_+_81591757 0.14 ENST00000558332.1
 IL16
 interleukin 16
chr17_-_43487741 0.13 ENST00000455881.1
 ARHGAP27
 Rho GTPase activating protein 27
chr3_-_112565703 0.13 ENST00000488794.1
 CD200R1L
 CD200 receptor 1-like
chr7_-_142247606 0.13 ENST00000390361.3
 TRBV7-3
 T cell receptor beta variable 7-3
chr2_+_75061108 0.13 ENST00000290573.2
 HK2
 hexokinase 2
chr6_-_66417107 0.13 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
 EYS
 eyes shut homolog (Drosophila)
chr6_-_26216872 0.12 ENST00000244601.3
 HIST1H2BG
 histone cluster 1, H2bg
chr19_-_36304201 0.12 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr20_-_43280325 0.11 ENST00000537820.1
 ADA
 adenosine deaminase
chr3_+_125687987 0.11 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
 ROPN1B
 rhophilin associated tail protein 1B
chr7_-_19813192 0.11 ENST00000422233.1
ENST00000433641.1
 TMEM196
 transmembrane protein 196
chr18_+_55862622 0.10 ENST00000456173.2
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_60869867 0.10 ENST00000347785.3
 CD5
 CD5 molecule
chr5_+_55147205 0.10 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
 IL31RA
 interleukin 31 receptor A
chr14_+_91580777 0.10 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
 C14orf159
 chromosome 14 open reading frame 159
chr17_-_39165366 0.10 ENST00000391588.1
 KRTAP3-1
 keratin associated protein 3-1
chr14_+_91580708 0.10 ENST00000518868.1
 C14orf159
 chromosome 14 open reading frame 159
chr20_+_44036900 0.10 ENST00000443296.1
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_+_91581011 0.10 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
 C14orf159
 chromosome 14 open reading frame 159
chr2_-_105030466 0.10 ENST00000449772.1
 AC068535.3
 AC068535.3
chr19_-_42724261 0.10 ENST00000595337.1
 DEDD2
 death effector domain containing 2
chr12_+_65563329 0.09 ENST00000308330.2
 LEMD3
 LEM domain containing 3
chr6_+_26273144 0.09 ENST00000377733.2
 HIST1H2BI
 histone cluster 1, H2bi
chr6_-_26124138 0.09 ENST00000314332.5
ENST00000396984.1
 HIST1H2BC
 histone cluster 1, H2bc
chr4_-_157563459 0.08 ENST00000504237.1
ENST00000511399.1
 RP11-171N4.2
 Uncharacterized protein
chr1_+_149804218 0.08 ENST00000610125.1
 HIST2H4A
 histone cluster 2, H4a
chr20_+_44036620 0.08 ENST00000372710.3
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr17_-_39093672 0.08 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23
 keratin 23 (histone deacetylase inducible)
chr7_+_39125365 0.08 ENST00000559001.1
ENST00000464276.2
 POU6F2
 POU class 6 homeobox 2
chr4_-_38666430 0.07 ENST00000436901.1
 AC021860.1
 Uncharacterized protein
chr1_-_226129083 0.07 ENST00000420304.2
 LEFTY2
 left-right determination factor 2
chr19_-_46148820 0.07 ENST00000587152.1
 EML2
 echinoderm microtubule associated protein like 2
chr1_-_44482979 0.07 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_-_208031943 0.07 ENST00000421199.1
ENST00000457962.1
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr11_-_133402410 0.07 ENST00000524381.1
 OPCML
 opioid binding protein/cell adhesion molecule-like
chr6_+_27775899 0.07 ENST00000358739.3
 HIST1H2AI
 histone cluster 1, H2ai
chr6_+_27806319 0.07 ENST00000606613.1
ENST00000396980.3
 HIST1H2BN
 histone cluster 1, H2bn
chr3_+_51741072 0.07 ENST00000395052.3
 GRM2
 glutamate receptor, metabotropic 2
chr15_+_22736484 0.07 ENST00000560659.2
 GOLGA6L1
 golgin A6 family-like 1
chr18_+_44526786 0.07 ENST00000245121.5
ENST00000356157.7
 KATNAL2
 katanin p60 subunit A-like 2
chr6_-_27782548 0.07 ENST00000333151.3
 HIST1H2AJ
 histone cluster 1, H2aj
chr10_+_129796390 0.06 ENST00000455661.1
 PTPRE
 protein tyrosine phosphatase, receptor type, E
chr15_+_22736246 0.06 ENST00000316397.3
 GOLGA6L1
 golgin A6 family-like 1
chr14_-_65409502 0.06 ENST00000389614.5
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr9_+_136399929 0.06 ENST00000393060.1
 ADAMTSL2
 ADAMTS-like 2
chr6_+_139349817 0.06 ENST00000367660.3
 ABRACL
 ABRA C-terminal like
chr6_+_27782788 0.06 ENST00000359465.4
 HIST1H2BM
 histone cluster 1, H2bm
chr11_+_72983246 0.06 ENST00000393590.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_-_58328923 0.06 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
 PRSS54
 protease, serine, 54
chr6_+_26217159 0.06 ENST00000303910.2
 HIST1H2AE
 histone cluster 1, H2ae
chr11_-_107729887 0.06 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr7_+_50348268 0.06 ENST00000438033.1
ENST00000439701.1
 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
chr18_+_43753974 0.05 ENST00000282059.6
ENST00000321319.6
 C18orf25
 chromosome 18 open reading frame 25
chr1_-_226129189 0.05 ENST00000366820.5
 LEFTY2
 left-right determination factor 2
chr14_+_91580732 0.05 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
 C14orf159
 chromosome 14 open reading frame 159
chr16_-_58328870 0.05 ENST00000543437.1
 PRSS54
 protease, serine, 54
chr19_+_51728316 0.05 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
 CD33
 CD33 molecule
chr17_+_36452989 0.05 ENST00000312513.5
ENST00000582535.1
 MRPL45
 mitochondrial ribosomal protein L45
chr20_-_60795296 0.05 ENST00000340177.5
 HRH3
 histamine receptor H3
chr10_+_94451574 0.05 ENST00000492654.2
 HHEX
 hematopoietically expressed homeobox
chr20_+_24449821 0.05 ENST00000376862.3
 SYNDIG1
 synapse differentiation inducing 1
chr19_-_35166604 0.05 ENST00000601241.1
 SCGB2B2
 secretoglobin, family 2B, member 2
chr12_-_323689 0.05 ENST00000428720.1
 SLC6A12
 solute carrier family 6 (neurotransmitter transporter), member 12
chr6_-_27841289 0.05 ENST00000355981.2
 HIST1H4L
 histone cluster 1, H4l
chr16_-_11036300 0.05 ENST00000331808.4
 DEXI
 Dexi homolog (mouse)
chr15_+_63796779 0.05 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
 USP3
 ubiquitin specific peptidase 3
chr2_+_28615669 0.04 ENST00000379619.1
ENST00000264716.4
 FOSL2
 FOS-like antigen 2
chr2_+_220110177 0.04 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
 STK16
 serine/threonine kinase 16
chrX_-_153523462 0.04 ENST00000361930.3
ENST00000369926.1
 TEX28
 testis expressed 28
chr11_+_46383121 0.04 ENST00000454345.1
 DGKZ
 diacylglycerol kinase, zeta
chr14_+_91580357 0.04 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
 C14orf159
 chromosome 14 open reading frame 159
chr1_-_156399184 0.04 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
 C1orf61
 chromosome 1 open reading frame 61
chr3_+_97868170 0.04 ENST00000437310.1
 OR5H14
 olfactory receptor, family 5, subfamily H, member 14
chr9_+_37485932 0.04 ENST00000377798.4
ENST00000442009.2
 POLR1E
 polymerase (RNA) I polypeptide E, 53kDa
chr1_-_89357179 0.04 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
 GTF2B
 general transcription factor IIB
chr2_-_239140011 0.04 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
 AC016757.3
 Protein LOC151174
chr14_-_65409438 0.04 ENST00000557049.1
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr7_+_142364193 0.04 ENST00000390397.2
 TRBV24-1
 T cell receptor beta variable 24-1
chr1_+_66797687 0.04 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
 PDE4B
 phosphodiesterase 4B, cAMP-specific
chr2_+_96991033 0.03 ENST00000420176.1
ENST00000536814.1
ENST00000439118.2
 ITPRIPL1
 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr1_+_90287480 0.03 ENST00000394593.3
 LRRC8D
 leucine rich repeat containing 8 family, member D
chr2_-_49381572 0.03 ENST00000454032.1
ENST00000304421.4
 FSHR
 follicle stimulating hormone receptor
chr11_-_72145426 0.03 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
 CLPB
 ClpB caseinolytic peptidase B homolog (E. coli)
chr6_-_99842041 0.03 ENST00000254759.3
ENST00000369242.1
 COQ3
 coenzyme Q3 methyltransferase
chr2_-_49381646 0.03 ENST00000346173.3
ENST00000406846.2
 FSHR
 follicle stimulating hormone receptor
chr2_+_16080659 0.03 ENST00000281043.3
 MYCN
 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr9_+_37486005 0.03 ENST00000377792.3
 POLR1E
 polymerase (RNA) I polypeptide E, 53kDa
chr6_+_41888926 0.03 ENST00000230340.4
 BYSL
 bystin-like
chr12_+_67663056 0.03 ENST00000545606.1
 CAND1
 cullin-associated and neddylation-dissociated 1
chr11_+_66406088 0.03 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
 RBM4
 RNA binding motif protein 4
chr19_+_41594377 0.03 ENST00000330436.3
 CYP2A13
 cytochrome P450, family 2, subfamily A, polypeptide 13
chr16_-_30773372 0.03 ENST00000545825.1
ENST00000541260.1
 C16orf93
 chromosome 16 open reading frame 93
chr2_-_71062938 0.02 ENST00000410009.3
 CD207
 CD207 molecule, langerin
chr16_-_15180257 0.02 ENST00000540462.1
 RRN3
 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_-_11042094 0.02 ENST00000377004.4
ENST00000377008.4
 C1orf127
 chromosome 1 open reading frame 127
chr11_+_35211511 0.02 ENST00000524922.1
 CD44
 CD44 molecule (Indian blood group)
chr8_-_80942061 0.02 ENST00000519386.1
 MRPS28
 mitochondrial ribosomal protein S28
chr9_+_21967137 0.02 ENST00000441769.2
 C9orf53
 chromosome 9 open reading frame 53
chr9_-_14910990 0.02 ENST00000380881.4
ENST00000422223.2
 FREM1
 FRAS1 related extracellular matrix 1
chr7_-_22862448 0.02 ENST00000358435.4
 TOMM7
 translocase of outer mitochondrial membrane 7 homolog (yeast)
chr12_+_50135327 0.02 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
 TMBIM6
 transmembrane BAX inhibitor motif containing 6
chrX_+_49832231 0.02 ENST00000376108.3
 CLCN5
 chloride channel, voltage-sensitive 5
chr3_+_12838161 0.02 ENST00000456430.2
 CAND2
 cullin-associated and neddylation-dissociated 2 (putative)
chr10_-_102046417 0.02 ENST00000370372.2
 BLOC1S2
 biogenesis of lysosomal organelles complex-1, subunit 2
chr2_-_239140276 0.02 ENST00000334973.4
 AC016757.3
 Protein LOC151174
chr12_+_50135351 0.02 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
 TMBIM6
 transmembrane BAX inhibitor motif containing 6
chr16_+_30483962 0.02 ENST00000356798.6
 ITGAL
 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr16_-_3306587 0.02 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
 MEFV
 Mediterranean fever
chr8_-_80942139 0.02 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
 MRPS28
 mitochondrial ribosomal protein S28
chr7_-_22862406 0.01 ENST00000372879.4
 TOMM7
 translocase of outer mitochondrial membrane 7 homolog (yeast)
chr16_+_30484021 0.01 ENST00000358164.5
 ITGAL
 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_9129631 0.01 ENST00000377414.3
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_-_55691377 0.01 ENST00000589172.1
 SYT5
 synaptotagmin V
chr6_+_123038689 0.01 ENST00000354275.2
ENST00000368446.1
 PKIB
 protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr1_+_202385953 0.01 ENST00000466968.1
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr3_-_123710893 0.01 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
 ROPN1
 rhophilin associated tail protein 1
chr6_+_146920097 0.01 ENST00000397944.3
ENST00000522242.1
 ADGB
 androglobin
chr6_+_146920116 0.01 ENST00000367493.3
 ADGB
 androglobin
chr6_-_27806117 0.01 ENST00000330180.2
 HIST1H2AK
 histone cluster 1, H2ak
chr9_+_114287433 0.01 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
 ZNF483
 zinc finger protein 483
chr6_+_27114861 0.01 ENST00000377459.1
 HIST1H2AH
 histone cluster 1, H2ah
chr14_+_102786063 0.01 ENST00000442396.2
ENST00000262236.5
 ZNF839
 zinc finger protein 839
chr16_-_84220604 0.01 ENST00000567759.1
 TAF1C
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr22_-_46644182 0.01 ENST00000404583.1
ENST00000404744.1
 CDPF1
 cysteine-rich, DPF motif domain containing 1
chr6_-_46922659 0.01 ENST00000265417.7
 GPR116
 G protein-coupled receptor 116
chr11_+_34938119 0.01 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
 PDHX
 pyruvate dehydrogenase complex, component X
chr8_-_101117847 0.01 ENST00000523287.1
ENST00000519092.1
 RGS22
 regulator of G-protein signaling 22
chr1_-_9129598 0.01 ENST00000535586.1
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_+_14219858 0.01 ENST00000306024.3
 LSM3
 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_-_101118210 0.01 ENST00000360863.6
 RGS22
 regulator of G-protein signaling 22
chr8_-_101118185 0.01 ENST00000523437.1
 RGS22
 regulator of G-protein signaling 22
chr7_+_141490017 0.01 ENST00000247883.4
 TAS2R5
 taste receptor, type 2, member 5
chr6_+_27861190 0.01 ENST00000303806.4
 HIST1H2BO
 histone cluster 1, H2bo
chr6_-_26285737 0.00 ENST00000377727.1
ENST00000289352.1
 HIST1H4H
 histone cluster 1, H4h
chr15_-_26874230 0.00 ENST00000400188.3
 GABRB3
 gamma-aminobutyric acid (GABA) A receptor, beta 3
chr16_+_30773636 0.00 ENST00000402121.3
ENST00000565995.1
ENST00000563683.1
ENST00000357890.5
ENST00000565931.1
 RNF40
 ring finger protein 40, E3 ubiquitin protein ligase
chr16_-_84220633 0.00 ENST00000566732.1
ENST00000561955.1
ENST00000564454.1
ENST00000341690.6
ENST00000541676.1
ENST00000570117.1
ENST00000564345.1
 TAF1C
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr7_+_133261209 0.00 ENST00000545148.1
 EXOC4
 exocyst complex component 4
chr6_+_116937636 0.00 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
 RSPH4A
 radial spoke head 4 homolog A (Chlamydomonas)
chr14_-_24551137 0.00 ENST00000396995.1
 NRL
 neural retina leucine zipper
chr18_+_13612613 0.00 ENST00000586765.1
 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
chr15_-_83316254 0.00 ENST00000567678.1
ENST00000450751.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr16_-_20681177 0.00 ENST00000524149.1
 ACSM1
 acyl-CoA synthetase medium-chain family member 1
chr6_+_27100811 0.00 ENST00000359193.2
 HIST1H2AG
 histone cluster 1, H2ag
chr6_+_292051 0.00 ENST00000344450.5
 DUSP22
 dual specificity phosphatase 22
chr2_+_204732487 0.00 ENST00000302823.3
 CTLA4
 cytotoxic T-lymphocyte-associated protein 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.4 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:1904925 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.0 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.6 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends