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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SMAD4

Z-value: 0.58

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Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
SMAD4
ENSG00000141646.9 SMAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48494361_484944260.551.6e-01Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr22_-_24641027 1.06 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
 GGT5
 gamma-glutamyltransferase 5
chr1_+_159141397 1.01 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chr5_+_156696362 0.71 ENST00000377576.3
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr13_+_102104980 0.67 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr7_+_94023873 0.66 ENST00000297268.6
 COL1A2
 collagen, type I, alpha 2
chr14_-_92413353 0.61 ENST00000556154.1
 FBLN5
 fibulin 5
chr13_+_102104952 0.61 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr1_+_159175201 0.60 ENST00000368121.2
 DARC
 Duffy blood group, atypical chemokine receptor
chr5_-_111093340 0.58 ENST00000508870.1
 NREP
 neuronal regeneration related protein
chr8_+_104384616 0.58 ENST00000520337.1
 CTHRC1
 collagen triple helix repeat containing 1
chr2_+_33359646 0.53 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.52 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr8_+_104383728 0.51 ENST00000330295.5
 CTHRC1
 collagen triple helix repeat containing 1
chr5_-_111092930 0.50 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr11_-_70672645 0.49 ENST00000423696.2
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr5_-_111093081 0.44 ENST00000453526.2
ENST00000509427.1
 NREP
 neuronal regeneration related protein
chr11_+_117070037 0.44 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
 TAGLN
 transgelin
chr12_-_91572278 0.43 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
 DCN
 decorin
chr8_-_120605194 0.41 ENST00000522167.1
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr5_-_111093406 0.40 ENST00000379671.3
 NREP
 neuronal regeneration related protein
chr9_+_120466610 0.40 ENST00000394487.4
 TLR4
 toll-like receptor 4
chr5_-_168727786 0.38 ENST00000332966.8
 SLIT3
 slit homolog 3 (Drosophila)
chr5_-_124081008 0.37 ENST00000306315.5
 ZNF608
 zinc finger protein 608
chr11_-_118550346 0.36 ENST00000530256.1
 TREH
 trehalase (brush-border membrane glycoprotein)
chr22_+_31003133 0.36 ENST00000405742.3
 TCN2
 transcobalamin II
chr12_+_53443963 0.34 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr10_+_31610064 0.34 ENST00000446923.2
ENST00000559476.1
 ZEB1
 zinc finger E-box binding homeobox 1
chr17_-_67138015 0.33 ENST00000284425.2
ENST00000590645.1
 ABCA6
 ATP-binding cassette, sub-family A (ABC1), member 6
chrX_+_100743031 0.33 ENST00000423738.3
 ARMCX4
 armadillo repeat containing, X-linked 4
chr5_-_121413974 0.32 ENST00000231004.4
 LOX
 lysyl oxidase
chr5_-_168727713 0.32 ENST00000404867.3
 SLIT3
 slit homolog 3 (Drosophila)
chr12_+_1738363 0.32 ENST00000397196.2
 WNT5B
 wingless-type MMTV integration site family, member 5B
chr22_+_31003190 0.31 ENST00000407817.3
 TCN2
 transcobalamin II
chr5_-_150521192 0.31 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr11_-_118550375 0.31 ENST00000525958.1
ENST00000264029.4
ENST00000397925.1
ENST00000529101.1
 TREH
 trehalase (brush-border membrane glycoprotein)
chr22_+_31002779 0.30 ENST00000215838.3
 TCN2
 transcobalamin II
chr3_+_154797877 0.30 ENST00000462745.1
ENST00000493237.1
 MME
 membrane metallo-endopeptidase
chr11_-_111794446 0.30 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr5_-_149535421 0.29 ENST00000261799.4
 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
chr1_-_32827682 0.29 ENST00000432622.1
 FAM229A
 family with sequence similarity 229, member A
chr19_+_37342547 0.29 ENST00000331800.4
ENST00000586646.1
 ZNF345
 zinc finger protein 345
chr5_-_168728103 0.28 ENST00000519560.1
 SLIT3
 slit homolog 3 (Drosophila)
chr14_-_106406090 0.28 ENST00000390593.2
 IGHV6-1
 immunoglobulin heavy variable 6-1
chrX_-_154250989 0.28 ENST00000360256.4
 F8
 coagulation factor VIII, procoagulant component
chr16_+_2880369 0.28 ENST00000572863.1
 ZG16B
 zymogen granule protein 16B
chr13_+_76378305 0.28 ENST00000526371.1
ENST00000526528.1
 LMO7
 LIM domain 7
chr2_+_30454390 0.27 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
 LBH
 limb bud and heart development
chr15_-_82338460 0.26 ENST00000558133.1
ENST00000329713.4
 MEX3B
 mex-3 RNA binding family member B
chr10_+_94451574 0.26 ENST00000492654.2
 HHEX
 hematopoietically expressed homeobox
chr17_-_19290117 0.25 ENST00000497081.2
 MFAP4
 microfibrillar-associated protein 4
chr4_-_100242549 0.25 ENST00000305046.8
ENST00000394887.3
 ADH1B
 alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_+_86511549 0.25 ENST00000533902.2
 PRSS23
 protease, serine, 23
chr19_+_49617581 0.25 ENST00000391864.3
 LIN7B
 lin-7 homolog B (C. elegans)
chr2_-_45236540 0.25 ENST00000303077.6
 SIX2
 SIX homeobox 2
chr1_-_153522562 0.25 ENST00000368714.1
 S100A4
 S100 calcium binding protein A4
chr3_+_126243126 0.25 ENST00000319340.2
 CHST13
 carbohydrate (chondroitin 4) sulfotransferase 13
chr16_+_2880157 0.25 ENST00000382280.3
 ZG16B
 zymogen granule protein 16B
chr13_+_76210448 0.24 ENST00000377499.5
 LMO7
 LIM domain 7
chr19_+_36359341 0.24 ENST00000221891.4
 APLP1
 amyloid beta (A4) precursor-like protein 1
chr1_-_31230650 0.23 ENST00000294507.3
 LAPTM5
 lysosomal protein transmembrane 5
chr5_+_148521136 0.23 ENST00000506113.1
 ABLIM3
 actin binding LIM protein family, member 3
chr5_+_148521046 0.23 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
 ABLIM3
 actin binding LIM protein family, member 3
chr22_+_44319648 0.23 ENST00000423180.2
 PNPLA3
 patatin-like phospholipase domain containing 3
chr2_+_217082311 0.23 ENST00000597904.1
 RP11-566E18.3
 RP11-566E18.3
chr5_+_148521381 0.23 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr7_-_100493482 0.22 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
 ACHE
 acetylcholinesterase (Yt blood group)
chr12_+_53443680 0.22 ENST00000314250.6
ENST00000451358.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_46616017 0.22 ENST00000542931.1
 TDGF1
 teratocarcinoma-derived growth factor 1
chr19_+_10527449 0.22 ENST00000592685.1
ENST00000380702.2
 PDE4A
 phosphodiesterase 4A, cAMP-specific
chr5_+_82767583 0.22 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
 VCAN
 versican
chr17_-_19290483 0.22 ENST00000395592.2
ENST00000299610.4
 MFAP4
 microfibrillar-associated protein 4
chr6_-_56707943 0.22 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
 DST
 dystonin
chr16_+_2880296 0.22 ENST00000571723.1
 ZG16B
 zymogen granule protein 16B
chr1_-_153599732 0.21 ENST00000392623.1
 S100A13
 S100 calcium binding protein A13
chr2_+_217524323 0.21 ENST00000456764.1
 IGFBP2
 insulin-like growth factor binding protein 2, 36kDa
chr15_+_67420441 0.21 ENST00000558894.1
 SMAD3
 SMAD family member 3
chrX_-_151143140 0.21 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
 GABRE
 gamma-aminobutyric acid (GABA) A receptor, epsilon
chr22_+_44319619 0.21 ENST00000216180.3
 PNPLA3
 patatin-like phospholipase domain containing 3
chr4_+_671711 0.21 ENST00000400159.2
 MYL5
 myosin, light chain 5, regulatory
chr3_+_106959530 0.20 ENST00000466734.1
ENST00000463143.1
ENST00000490441.1
 LINC00883
 long intergenic non-protein coding RNA 883
chr13_+_76378357 0.20 ENST00000489941.2
ENST00000525373.1
 LMO7
 LIM domain 7
chr1_-_232697304 0.20 ENST00000366630.1
 SIPA1L2
 signal-induced proliferation-associated 1 like 2
chr4_+_126237554 0.20 ENST00000394329.3
 FAT4
 FAT atypical cadherin 4
chr11_-_111781554 0.20 ENST00000526167.1
ENST00000528961.1
 CRYAB
 crystallin, alpha B
chr5_+_126626498 0.20 ENST00000503335.2
ENST00000508365.1
ENST00000418761.2
ENST00000274473.6
 MEGF10
 multiple EGF-like-domains 10
chr9_-_21305312 0.20 ENST00000259555.4
 IFNA5
 interferon, alpha 5
chr12_+_75874460 0.20 ENST00000266659.3
 GLIPR1
 GLI pathogenesis-related 1
chr3_-_48594248 0.19 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
 PFKFB4
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr11_-_111781454 0.19 ENST00000533280.1
 CRYAB
 crystallin, alpha B
chr19_+_51628165 0.19 ENST00000250360.3
ENST00000440804.3
 SIGLEC9
 sialic acid binding Ig-like lectin 9
chr1_+_210406121 0.19 ENST00000367012.3
 SERTAD4
 SERTA domain containing 4
chr7_-_100493744 0.19 ENST00000428317.1
ENST00000441605.1
 ACHE
 acetylcholinesterase (Yt blood group)
chr20_+_34680620 0.19 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
chr12_+_75874984 0.19 ENST00000550491.1
 GLIPR1
 GLI pathogenesis-related 1
chr10_+_102891048 0.19 ENST00000467928.2
 TLX1
 T-cell leukemia homeobox 1
chr11_-_111781610 0.18 ENST00000525823.1
 CRYAB
 crystallin, alpha B
chr12_-_31744031 0.18 ENST00000389082.5
 DENND5B
 DENN/MADD domain containing 5B
chr3_-_48632593 0.18 ENST00000454817.1
ENST00000328333.8
 COL7A1
 collagen, type VII, alpha 1
chr5_-_127674883 0.18 ENST00000507835.1
 FBN2
 fibrillin 2
chr3_-_114477962 0.18 ENST00000471418.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr10_+_91087651 0.18 ENST00000371818.4
 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
chr16_-_31076332 0.18 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668
 zinc finger protein 668
chr9_+_99690592 0.18 ENST00000354649.3
 NUTM2G
 NUT family member 2G
chr3_+_141103634 0.18 ENST00000507722.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr10_+_81892347 0.18 ENST00000372267.2
 PLAC9
 placenta-specific 9
chr14_+_21538429 0.18 ENST00000298694.4
ENST00000555038.1
 ARHGEF40
 Rho guanine nucleotide exchange factor (GEF) 40
chr13_+_31309645 0.18 ENST00000380490.3
 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
chr9_-_139891165 0.17 ENST00000494426.1
 CLIC3
 chloride intracellular channel 3
chr12_+_75874580 0.17 ENST00000456650.3
 GLIPR1
 GLI pathogenesis-related 1
chr14_+_21538517 0.17 ENST00000298693.3
 ARHGEF40
 Rho guanine nucleotide exchange factor (GEF) 40
chrX_+_54835493 0.17 ENST00000396224.1
 MAGED2
 melanoma antigen family D, 2
chr14_+_21156915 0.17 ENST00000397990.4
ENST00000555597.1
 ANG
RNASE4
 angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr19_+_41768561 0.17 ENST00000599719.1
ENST00000601309.1
 HNRNPUL1
 heterogeneous nuclear ribonucleoprotein U-like 1
chr1_+_110210644 0.17 ENST00000369831.2
ENST00000442650.1
ENST00000369827.3
ENST00000460717.3
ENST00000241337.4
ENST00000467579.3
ENST00000414179.2
ENST00000369829.2
 GSTM2
 glutathione S-transferase mu 2 (muscle)
chr11_-_27722021 0.17 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
 BDNF
 brain-derived neurotrophic factor
chr1_+_110036728 0.17 ENST00000369868.3
ENST00000430195.2
 CYB561D1
 cytochrome b561 family, member D1
chr10_-_62704005 0.17 ENST00000337910.5
 RHOBTB1
 Rho-related BTB domain containing 1
chr4_-_95264008 0.16 ENST00000295256.5
 HPGDS
 hematopoietic prostaglandin D synthase
chr5_+_140529630 0.16 ENST00000543635.1
 PCDHB6
 protocadherin beta 6
chr22_+_31090793 0.16 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
 OSBP2
 oxysterol binding protein 2
chr6_+_41010293 0.16 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
 TSPO2
 translocator protein 2
chr15_-_83316254 0.16 ENST00000567678.1
ENST00000450751.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr5_+_149569520 0.16 ENST00000230671.2
ENST00000524041.1
 SLC6A7
 solute carrier family 6 (neurotransmitter transporter), member 7
chrX_+_153029633 0.16 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
 PLXNB3
 plexin B3
chr11_-_65150103 0.16 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
 SLC25A45
 solute carrier family 25, member 45
chr5_-_124080203 0.16 ENST00000504926.1
 ZNF608
 zinc finger protein 608
chr11_+_67777751 0.16 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
chr7_-_141646726 0.16 ENST00000438351.1
ENST00000439991.1
ENST00000551012.2
ENST00000546910.1
 CLEC5A
 C-type lectin domain family 5, member A
chr8_-_57472154 0.16 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
 LINC00968
 long intergenic non-protein coding RNA 968
chr11_-_3186494 0.16 ENST00000389989.3
ENST00000542243.1
 OSBPL5
 oxysterol binding protein-like 5
chr15_-_43910998 0.15 ENST00000450892.2
 STRC
 stereocilin
chr7_+_20687017 0.15 ENST00000258738.6
 ABCB5
 ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_+_110036699 0.15 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
 CYB561D1
 cytochrome b561 family, member D1
chr14_+_103566481 0.15 ENST00000380069.3
 EXOC3L4
 exocyst complex component 3-like 4
chr19_-_46285736 0.15 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
 DMPK
 dystrophia myotonica-protein kinase
chr22_+_23077065 0.15 ENST00000390310.2
 IGLV2-18
 immunoglobulin lambda variable 2-18
chr19_-_46285646 0.15 ENST00000458663.2
 DMPK
 dystrophia myotonica-protein kinase
chr19_-_47922373 0.15 ENST00000559524.1
ENST00000557833.1
ENST00000558555.1
ENST00000561293.1
ENST00000441740.2
 MEIS3
 Meis homeobox 3
chr17_-_76870126 0.15 ENST00000586057.1
 TIMP2
 TIMP metallopeptidase inhibitor 2
chr11_+_64879317 0.15 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
 TM7SF2
 transmembrane 7 superfamily member 2
chr1_-_46598371 0.15 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_-_127963343 0.15 ENST00000335247.7
 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
chr20_-_56265680 0.15 ENST00000414037.1
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr11_+_86511569 0.15 ENST00000441050.1
 PRSS23
 protease, serine, 23
chr22_+_31518938 0.14 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J
 inositol polyphosphate-5-phosphatase J
chr11_+_43964055 0.14 ENST00000528572.1
 C11orf96
 chromosome 11 open reading frame 96
chr2_-_175711133 0.14 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chrX_-_51812268 0.14 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
 MAGED4B
 melanoma antigen family D, 4B
chr1_-_154461642 0.14 ENST00000555188.1
 SHE
 Src homology 2 domain containing E
chr6_+_116892530 0.14 ENST00000466444.2
ENST00000368590.5
ENST00000392526.1
 RWDD1
 RWD domain containing 1
chr6_+_39760129 0.14 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr7_-_150675372 0.14 ENST00000262186.5
 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_9958870 0.14 ENST00000413608.1
 IL17RC
 interleukin 17 receptor C
chr19_+_49617609 0.14 ENST00000221459.2
ENST00000486217.2
 LIN7B
 lin-7 homolog B (C. elegans)
chr16_-_31076273 0.14 ENST00000426488.2
 ZNF668
 zinc finger protein 668
chr8_+_38586068 0.14 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr10_+_72972281 0.14 ENST00000335350.6
 UNC5B
 unc-5 homolog B (C. elegans)
chrX_-_48328631 0.14 ENST00000429543.1
ENST00000317669.5
 SLC38A5
 solute carrier family 38, member 5
chr3_+_9958758 0.14 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
 IL17RC
 interleukin 17 receptor C
chr2_+_201170703 0.14 ENST00000358677.5
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr22_-_38851205 0.14 ENST00000303592.3
 KCNJ4
 potassium inwardly-rectifying channel, subfamily J, member 4
chrX_-_48328551 0.14 ENST00000376876.3
 SLC38A5
 solute carrier family 38, member 5
chr15_+_43803143 0.14 ENST00000382031.1
 MAP1A
 microtubule-associated protein 1A
chr3_+_50316458 0.14 ENST00000316436.3
 LSMEM2
 leucine-rich single-pass membrane protein 2
chr8_+_38585704 0.13 ENST00000519416.1
ENST00000520615.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr16_+_31483374 0.13 ENST00000394863.3
 TGFB1I1
 transforming growth factor beta 1 induced transcript 1
chr15_-_52944231 0.13 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr11_-_5462744 0.13 ENST00000380211.1
 OR51I1
 olfactory receptor, family 51, subfamily I, member 1
chr9_+_72658490 0.13 ENST00000377182.4
 MAMDC2
 MAM domain containing 2
chr10_-_28287968 0.13 ENST00000305242.5
 ARMC4
 armadillo repeat containing 4
chrX_-_48931648 0.13 ENST00000376386.3
ENST00000376390.4
 PRAF2
 PRA1 domain family, member 2
chr1_-_46598284 0.13 ENST00000423209.1
ENST00000262741.5
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr10_+_26505594 0.13 ENST00000259271.3
 GAD2
 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr22_+_22930626 0.13 ENST00000390302.2
 IGLV2-33
 immunoglobulin lambda variable 2-33 (non-functional)
chr4_+_74718906 0.13 ENST00000226524.3
 PF4V1
 platelet factor 4 variant 1
chr16_-_54320675 0.13 ENST00000329734.3
 IRX3
 iroquois homeobox 3
chr3_+_187086120 0.13 ENST00000259030.2
 RTP4
 receptor (chemosensory) transporter protein 4
chr9_+_140119618 0.13 ENST00000359069.2
 C9orf169
 chromosome 9 open reading frame 169
chr2_+_201997676 0.13 ENST00000462763.1
ENST00000479953.2
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr2_+_42721689 0.13 ENST00000405592.1
 MTA3
 metastasis associated 1 family, member 3
chr4_-_39640700 0.13 ENST00000295958.5
 SMIM14
 small integral membrane protein 14
chrX_-_102757802 0.13 ENST00000372633.1
 RAB40A
 RAB40A, member RAS oncogene family
chr19_+_48898132 0.12 ENST00000263269.3
 GRIN2D
 glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr1_+_180165672 0.12 ENST00000443059.1
 QSOX1
 quiescin Q6 sulfhydryl oxidase 1
chr4_+_55524085 0.12 ENST00000412167.2
ENST00000288135.5
 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr1_-_238649319 0.12 ENST00000400946.2
 RP11-371I1.2
 long intergenic non-protein coding RNA 1139
chr20_+_43538756 0.12 ENST00000537323.1
ENST00000217073.2
 PABPC1L
 poly(A) binding protein, cytoplasmic 1-like
chr6_+_84222194 0.12 ENST00000536636.1
 PRSS35
 protease, serine, 35
chr9_+_34652164 0.12 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr6_+_108487245 0.12 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chr16_+_2880254 0.12 ENST00000570670.1
 ZG16B
 zymogen granule protein 16B
chr1_+_11751748 0.12 ENST00000294485.5
 DRAXIN
 dorsal inhibitory axon guidance protein
chr21_+_39628655 0.12 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr20_+_43538692 0.12 ENST00000217074.4
ENST00000255136.3
 PABPC1L
 poly(A) binding protein, cytoplasmic 1-like
chrX_+_54947229 0.12 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
 TRO
 trophinin
chr19_+_41117770 0.12 ENST00000601032.1
 LTBP4
 latent transforming growth factor beta binding protein 4
chr10_+_81891416 0.12 ENST00000372270.2
 PLAC9
 placenta-specific 9
chr22_-_31503490 0.12 ENST00000400299.2
 SELM
 Selenoprotein M
chr11_-_118213360 0.12 ENST00000529594.1
 CD3D
 CD3d molecule, delta (CD3-TCR complex)
chr6_-_87804815 0.12 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 1.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 1.0 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) apoptotic process involved in luteolysis(GO:0061364)
0.1 0.4 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.3 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.3 GO:0046449 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.2 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.7 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.8 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.1 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.6 GO:0030208 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.1 GO:2000737 negative regulation of stem cell differentiation(GO:2000737)
0.0 0.3 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.0 GO:1903524 regulation of vasoconstriction(GO:0019229) positive regulation of vasoconstriction(GO:0045907) positive regulation of blood circulation(GO:1903524)
0.0 0.1 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:1904404 transcription factor catabolic process(GO:0036369) cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.0 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.3 GO:0007517 muscle organ development(GO:0007517)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.0 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0002251 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.4 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.9 GO:0001895 retina homeostasis(GO:0001895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.0 GO:0033643 host cell part(GO:0033643)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.1 0.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.0 GO:0043125 ErbB-2 class receptor binding(GO:0005176) ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0033300 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) dehydroascorbic acid transporter activity(GO:0033300) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.0 GO:0005119 smoothened binding(GO:0005119)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels