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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SOX10_SOX15

Z-value: 1.14

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Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
SOX10
ENSG00000100146.12 SOX10
SOX15
ENSG00000129194.3 SOX15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX15hg19_v2_chr17_-_7493390_7493488-0.902.2e-03Click!
SOX10hg19_v2_chr22_-_38380543_38380569-0.811.6e-02Click!

Activity profile of SOX10_SOX15 motif

Sorted Z-values of SOX10_SOX15 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_159141397 1.67 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chr1_+_163038565 0.85 ENST00000421743.2
 RGS4
 regulator of G-protein signaling 4
chr5_-_111093081 0.82 ENST00000453526.2
ENST00000509427.1
 NREP
 neuronal regeneration related protein
chr5_-_111092873 0.79 ENST00000509025.1
ENST00000515855.1
 NREP
 neuronal regeneration related protein
chr5_-_111093167 0.70 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr5_-_111092930 0.67 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr8_+_97597148 0.64 ENST00000521590.1
 SDC2
 syndecan 2
chr1_+_183774240 0.61 ENST00000360851.3
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr14_-_51027838 0.59 ENST00000555216.1
 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
chr6_+_114178512 0.58 ENST00000368635.4
 MARCKS
 myristoylated alanine-rich protein kinase C substrate
chr3_+_151986709 0.56 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
 MBNL1
 muscleblind-like splicing regulator 1
chr15_+_63335899 0.53 ENST00000561266.1
 TPM1
 tropomyosin 1 (alpha)
chrX_+_12993202 0.52 ENST00000451311.2
ENST00000380636.1
 TMSB4X
 thymosin beta 4, X-linked
chr6_+_72596604 0.52 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
 RIMS1
 regulating synaptic membrane exocytosis 1
chr1_+_215256467 0.49 ENST00000391894.2
ENST00000444842.2
 KCNK2
 potassium channel, subfamily K, member 2
chrX_+_80457442 0.49 ENST00000373212.5
 SH3BGRL
 SH3 domain binding glutamic acid-rich protein like
chr3_+_141105235 0.49 ENST00000503809.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr20_-_45985172 0.48 ENST00000536340.1
 ZMYND8
 zinc finger, MYND-type containing 8
chr5_-_150521192 0.46 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr15_-_52944231 0.45 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr7_+_44788430 0.42 ENST00000457123.1
ENST00000309315.4
 ZMIZ2
 zinc finger, MIZ-type containing 2
chr12_+_53443680 0.42 ENST00000314250.6
ENST00000451358.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr12_+_53443963 0.42 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_47799542 0.40 ENST00000471289.2
ENST00000450808.2
 CMPK1
 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chrX_-_142722897 0.38 ENST00000338017.4
 SLITRK4
 SLIT and NTRK-like family, member 4
chr4_-_138453606 0.36 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
 PCDH18
 protocadherin 18
chr17_+_75447326 0.35 ENST00000591088.1
 SEPT9
 septin 9
chrX_+_12993336 0.35 ENST00000380635.1
 TMSB4X
 thymosin beta 4, X-linked
chr11_-_66445219 0.35 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
 RBM4B
 RNA binding motif protein 4B
chr5_-_65017921 0.34 ENST00000381007.4
 SGTB
 small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr3_+_133118839 0.33 ENST00000302334.2
 BFSP2
 beaded filament structural protein 2, phakinin
chrX_-_106960285 0.33 ENST00000503515.1
ENST00000372397.2
 TSC22D3
 TSC22 domain family, member 3
chr20_-_45984401 0.32 ENST00000311275.7
 ZMYND8
 zinc finger, MYND-type containing 8
chr2_-_188312971 0.32 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
 CALCRL
 calcitonin receptor-like
chr13_-_33780133 0.31 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr20_+_33292068 0.30 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
 TP53INP2
 tumor protein p53 inducible nuclear protein 2
chr1_-_26233423 0.30 ENST00000357865.2
 STMN1
 stathmin 1
chr7_-_47621736 0.30 ENST00000311160.9
 TNS3
 tensin 3
chr16_-_73082274 0.29 ENST00000268489.5
 ZFHX3
 zinc finger homeobox 3
chr2_-_37899323 0.29 ENST00000295324.3
ENST00000457889.1
 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
chr5_-_14871866 0.27 ENST00000284268.6
 ANKH
 ANKH inorganic pyrophosphate transport regulator
chr6_+_108881012 0.27 ENST00000343882.6
 FOXO3
 forkhead box O3
chr2_-_179343226 0.27 ENST00000434643.2
 FKBP7
 FK506 binding protein 7
chr1_+_197886461 0.27 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
 LHX9
 LIM homeobox 9
chr12_+_15475462 0.26 ENST00000543886.1
ENST00000348962.2
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr2_-_179343268 0.26 ENST00000424785.2
 FKBP7
 FK506 binding protein 7
chr3_-_18466026 0.25 ENST00000417717.2
 SATB1
 SATB homeobox 1
chr18_+_6729698 0.25 ENST00000383472.4
 ARHGAP28
 Rho GTPase activating protein 28
chr1_-_79472365 0.25 ENST00000370742.3
 ELTD1
 EGF, latrophilin and seven transmembrane domain containing 1
chr17_-_9940058 0.24 ENST00000585266.1
 GAS7
 growth arrest-specific 7
chr15_-_82338460 0.24 ENST00000558133.1
ENST00000329713.4
 MEX3B
 mex-3 RNA binding family member B
chr1_+_64239657 0.23 ENST00000371080.1
ENST00000371079.1
 ROR1
 receptor tyrosine kinase-like orphan receptor 1
chr2_-_166060571 0.23 ENST00000360093.3
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr6_+_56911476 0.22 ENST00000545356.1
 KIAA1586
 KIAA1586
chr16_+_53242350 0.22 ENST00000565442.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr1_+_201857798 0.22 ENST00000362011.6
 SHISA4
 shisa family member 4
chr13_-_41593425 0.21 ENST00000239882.3
 ELF1
 E74-like factor 1 (ets domain transcription factor)
chr9_-_120177342 0.21 ENST00000361209.2
 ASTN2
 astrotactin 2
chr20_+_61448376 0.21 ENST00000343916.3
 COL9A3
 collagen, type IX, alpha 3
chr18_+_72201664 0.21 ENST00000358821.3
 CNDP1
 carnosine dipeptidase 1 (metallopeptidase M20 family)
chr1_-_182360498 0.21 ENST00000417584.2
 GLUL
 glutamate-ammonia ligase
chr16_-_30798492 0.20 ENST00000262525.4
 ZNF629
 zinc finger protein 629
chr2_-_166060552 0.20 ENST00000283254.7
ENST00000453007.1
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr2_-_175711133 0.20 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr22_+_39052632 0.20 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
 CBY1
 chibby homolog 1 (Drosophila)
chr11_+_20044600 0.20 ENST00000311043.8
 NAV2
 neuron navigator 2
chr5_+_140729649 0.19 ENST00000523390.1
 PCDHGB1
 protocadherin gamma subfamily B, 1
chr1_+_33722080 0.19 ENST00000483388.1
ENST00000539719.1
 ZNF362
 zinc finger protein 362
chr2_+_120517174 0.18 ENST00000263708.2
 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr20_-_30310797 0.17 ENST00000422920.1
 BCL2L1
 BCL2-like 1
chr9_+_96846740 0.17 ENST00000288976.3
 PTPDC1
 protein tyrosine phosphatase domain containing 1
chr9_-_73483958 0.17 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
chr11_-_111781454 0.17 ENST00000533280.1
 CRYAB
 crystallin, alpha B
chr5_+_138089100 0.17 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
chr6_+_119215308 0.17 ENST00000229595.5
 ASF1A
 anti-silencing function 1A histone chaperone
chr10_+_22605374 0.17 ENST00000448361.1
 COMMD3
 COMM domain containing 3
chr1_-_11751529 0.17 ENST00000376672.1
 MAD2L2
 MAD2 mitotic arrest deficient-like 2 (yeast)
chr2_-_72374948 0.17 ENST00000546307.1
ENST00000474509.1
 CYP26B1
 cytochrome P450, family 26, subfamily B, polypeptide 1
chr4_+_71588372 0.16 ENST00000536664.1
 RUFY3
 RUN and FYVE domain containing 3
chr11_-_9286921 0.16 ENST00000328194.3
 DENND5A
 DENN/MADD domain containing 5A
chr4_-_140477928 0.16 ENST00000274031.3
 SETD7
 SET domain containing (lysine methyltransferase) 7
chr1_-_154155675 0.16 ENST00000330188.9
ENST00000341485.5
 TPM3
 tropomyosin 3
chr15_+_52043758 0.16 ENST00000249700.4
ENST00000539962.2
 TMOD2
 tropomodulin 2 (neuronal)
chr12_+_104359641 0.16 ENST00000537100.1
 TDG
 thymine-DNA glycosylase
chr10_-_99393208 0.16 ENST00000307450.6
 MORN4
 MORN repeat containing 4
chr1_-_95391315 0.16 ENST00000545882.1
ENST00000415017.1
 CNN3
 calponin 3, acidic
chr18_+_6729725 0.16 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
 ARHGAP28
 Rho GTPase activating protein 28
chr8_-_124553437 0.15 ENST00000517956.1
ENST00000443022.2
 FBXO32
 F-box protein 32
chr1_-_11751665 0.15 ENST00000376667.3
ENST00000235310.3
 MAD2L2
 MAD2 mitotic arrest deficient-like 2 (yeast)
chrX_+_10124977 0.15 ENST00000380833.4
 CLCN4
 chloride channel, voltage-sensitive 4
chrX_-_13956497 0.15 ENST00000398361.3
 GPM6B
 glycoprotein M6B
chr12_-_42631529 0.15 ENST00000548917.1
 YAF2
 YY1 associated factor 2
chr18_+_72201829 0.15 ENST00000582365.1
 CNDP1
 carnosine dipeptidase 1 (metallopeptidase M20 family)
chr11_-_111781610 0.15 ENST00000525823.1
 CRYAB
 crystallin, alpha B
chr16_+_53241854 0.15 ENST00000565803.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr11_-_111781554 0.15 ENST00000526167.1
ENST00000528961.1
 CRYAB
 crystallin, alpha B
chr14_+_77228532 0.15 ENST00000167106.4
ENST00000554237.1
 VASH1
 vasohibin 1
chr4_+_150999418 0.15 ENST00000296550.7
 DCLK2
 doublecortin-like kinase 2
chr15_-_57210769 0.15 ENST00000559000.1
 ZNF280D
 zinc finger protein 280D
chr12_-_109915098 0.14 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
 KCTD10
 potassium channel tetramerization domain containing 10
chr3_-_151102529 0.14 ENST00000302632.3
 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
chr7_-_27142290 0.14 ENST00000222718.5
 HOXA2
 homeobox A2
chr12_+_32260085 0.14 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
 BICD1
 bicaudal D homolog 1 (Drosophila)
chr12_+_26111823 0.14 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr18_+_3448455 0.14 ENST00000549780.1
 TGIF1
 TGFB-induced factor homeobox 1
chrX_+_70503433 0.14 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
 NONO
 non-POU domain containing, octamer-binding
chr2_-_163099885 0.13 ENST00000443424.1
 FAP
 fibroblast activation protein, alpha
chr5_+_140864649 0.13 ENST00000306593.1
 PCDHGC4
 protocadherin gamma subfamily C, 4
chr1_-_113247543 0.13 ENST00000414971.1
ENST00000534717.1
 RHOC
 ras homolog family member C
chr10_+_22605304 0.13 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
 COMMD3-BMI1
COMMD3
 COMMD3-BMI1 readthrough
COMM domain containing 3
chr2_-_86564776 0.13 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
 REEP1
 receptor accessory protein 1
chr9_-_14308004 0.13 ENST00000493697.1
 NFIB
 nuclear factor I/B
chr5_+_140743859 0.13 ENST00000518069.1
 PCDHGA5
 protocadherin gamma subfamily A, 5
chr5_-_171711061 0.13 ENST00000393792.2
 UBTD2
 ubiquitin domain containing 2
chr7_-_128415844 0.13 ENST00000249389.2
 OPN1SW
 opsin 1 (cone pigments), short-wave-sensitive
chr14_-_50999190 0.13 ENST00000557390.1
 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
chr4_-_138453559 0.13 ENST00000511115.1
 PCDH18
 protocadherin 18
chr17_+_7461613 0.12 ENST00000438470.1
ENST00000436057.1
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chr11_-_6677018 0.12 ENST00000299441.3
 DCHS1
 dachsous cadherin-related 1
chr19_+_1249869 0.12 ENST00000591446.2
 MIDN
 midnolin
chr13_+_30002846 0.12 ENST00000542829.1
 MTUS2
 microtubule associated tumor suppressor candidate 2
chr11_+_111807863 0.12 ENST00000440460.2
 DIXDC1
 DIX domain containing 1
chr2_-_85625857 0.12 ENST00000453973.1
 CAPG
 capping protein (actin filament), gelsolin-like
chr1_+_228337553 0.12 ENST00000366714.2
 GJC2
 gap junction protein, gamma 2, 47kDa
chr5_+_43602750 0.12 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
 NNT
 nicotinamide nucleotide transhydrogenase
chr8_+_81398444 0.11 ENST00000455036.3
ENST00000426744.2
 ZBTB10
 zinc finger and BTB domain containing 10
chr10_-_70092671 0.11 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
 PBLD
 phenazine biosynthesis-like protein domain containing
chr20_+_11898507 0.11 ENST00000378226.2
 BTBD3
 BTB (POZ) domain containing 3
chr7_-_111846435 0.11 ENST00000437633.1
ENST00000428084.1
 DOCK4
 dedicator of cytokinesis 4
chr10_+_35484793 0.11 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
 CREM
 cAMP responsive element modulator
chr3_-_46904946 0.11 ENST00000292327.4
 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_-_46904918 0.11 ENST00000395869.1
 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
chr15_+_57210961 0.11 ENST00000557843.1
 TCF12
 transcription factor 12
chr1_-_151431909 0.11 ENST00000361398.3
ENST00000271715.2
 POGZ
 pogo transposable element with ZNF domain
chr7_+_134551583 0.11 ENST00000435928.1
 CALD1
 caldesmon 1
chr11_-_89224299 0.11 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
 NOX4
 NADPH oxidase 4
chr16_+_30406721 0.11 ENST00000320159.2
 ZNF48
 zinc finger protein 48
chr4_-_5890145 0.11 ENST00000397890.2
 CRMP1
 collapsin response mediator protein 1
chr4_-_109090106 0.11 ENST00000379951.2
 LEF1
 lymphoid enhancer-binding factor 1
chr17_-_56065484 0.11 ENST00000581208.1
 VEZF1
 vascular endothelial zinc finger 1
chr10_-_70092635 0.10 ENST00000309049.4
 PBLD
 phenazine biosynthesis-like protein domain containing
chr5_+_140710061 0.10 ENST00000517417.1
ENST00000378105.3
 PCDHGA1
 protocadherin gamma subfamily A, 1
chr19_+_10765699 0.10 ENST00000590009.1
 ILF3
 interleukin enhancer binding factor 3, 90kDa
chr16_-_15736881 0.10 ENST00000540441.2
 KIAA0430
 KIAA0430
chr19_+_47105309 0.10 ENST00000599839.1
ENST00000596362.1
 CALM3
 calmodulin 3 (phosphorylase kinase, delta)
chr17_-_76713100 0.10 ENST00000585509.1
 CYTH1
 cytohesin 1
chr19_-_5340730 0.10 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
 PTPRS
 protein tyrosine phosphatase, receptor type, S
chr22_-_41636929 0.10 ENST00000216241.9
 CHADL
 chondroadherin-like
chr11_-_117166276 0.10 ENST00000510630.1
ENST00000392937.6
 BACE1
 beta-site APP-cleaving enzyme 1
chr17_-_56605341 0.10 ENST00000583114.1
 SEPT4
 septin 4
chr16_-_46865047 0.10 ENST00000394806.2
 C16orf87
 chromosome 16 open reading frame 87
chr11_-_10830463 0.10 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
chr3_-_71353892 0.10 ENST00000484350.1
 FOXP1
 forkhead box P1
chr17_-_46690839 0.10 ENST00000498634.2
 HOXB8
 homeobox B8
chr6_+_101846664 0.10 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
 GRIK2
 glutamate receptor, ionotropic, kainate 2
chr1_-_225840747 0.10 ENST00000366843.2
ENST00000366844.3
 ENAH
 enabled homolog (Drosophila)
chr5_-_114515734 0.10 ENST00000514154.1
ENST00000282369.3
 TRIM36
 tripartite motif containing 36
chr4_-_109089573 0.10 ENST00000265165.1
 LEF1
 lymphoid enhancer-binding factor 1
chr11_+_126081662 0.09 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
 FAM118B
 family with sequence similarity 118, member B
chr19_-_38720294 0.09 ENST00000412732.1
ENST00000456296.1
 DPF1
 D4, zinc and double PHD fingers family 1
chr19_-_18717627 0.09 ENST00000392386.3
 CRLF1
 cytokine receptor-like factor 1
chr1_+_185703513 0.09 ENST00000271588.4
ENST00000367492.2
 HMCN1
 hemicentin 1
chr3_-_48700310 0.09 ENST00000164024.4
ENST00000544264.1
 CELSR3
 cadherin, EGF LAG seven-pass G-type receptor 3
chr10_+_35415719 0.09 ENST00000474362.1
ENST00000374721.3
 CREM
 cAMP responsive element modulator
chr9_-_73736511 0.09 ENST00000377110.3
ENST00000377111.2
 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
chr19_-_38720354 0.09 ENST00000416611.1
 DPF1
 D4, zinc and double PHD fingers family 1
chr1_+_93645314 0.09 ENST00000343253.7
 CCDC18
 coiled-coil domain containing 18
chr2_+_149402553 0.09 ENST00000258484.6
ENST00000409654.1
 EPC2
 enhancer of polycomb homolog 2 (Drosophila)
chr17_-_53046058 0.09 ENST00000571584.1
ENST00000299335.3
 COX11
 cytochrome c oxidase assembly homolog 11 (yeast)
chr17_+_75283973 0.09 ENST00000431235.2
ENST00000449803.2
 SEPT9
 septin 9
chrX_-_21776281 0.09 ENST00000379494.3
 SMPX
 small muscle protein, X-linked
chr15_+_92937058 0.09 ENST00000268164.3
 ST8SIA2
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr1_+_244998602 0.09 ENST00000411948.2
 COX20
 COX20 cytochrome C oxidase assembly factor
chr4_-_76598544 0.09 ENST00000515457.1
ENST00000357854.3
 G3BP2
 GTPase activating protein (SH3 domain) binding protein 2
chr5_+_140480083 0.09 ENST00000231130.2
 PCDHB3
 protocadherin beta 3
chr22_+_27053422 0.08 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
 MIAT
 myocardial infarction associated transcript (non-protein coding)
chr10_+_35415978 0.08 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
 CREM
 cAMP responsive element modulator
chr14_-_35099315 0.08 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
 SNX6
 sorting nexin 6
chr22_-_36357671 0.08 ENST00000408983.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_+_19710468 0.08 ENST00000366425.3
 GP1BB
 glycoprotein Ib (platelet), beta polypeptide
chr17_+_26698677 0.08 ENST00000457710.3
 SARM1
 sterile alpha and TIR motif containing 1
chr13_+_49684445 0.08 ENST00000398316.3
 FNDC3A
 fibronectin type III domain containing 3A
chr8_+_81397876 0.08 ENST00000430430.1
 ZBTB10
 zinc finger and BTB domain containing 10
chr22_+_31742875 0.08 ENST00000504184.2
 AC005003.1
 CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chr10_+_99079008 0.08 ENST00000371021.3
 FRAT1
 frequently rearranged in advanced T-cell lymphomas
chr3_-_167813672 0.08 ENST00000470487.1
 GOLIM4
 golgi integral membrane protein 4
chr6_+_64282447 0.08 ENST00000370650.2
ENST00000578299.1
 PTP4A1
 protein tyrosine phosphatase type IVA, member 1
chr8_-_121824374 0.07 ENST00000517992.1
 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_-_71551868 0.07 ENST00000247829.3
 TSPAN8
 tetraspanin 8
chr15_+_62359175 0.07 ENST00000355522.5
 C2CD4A
 C2 calcium-dependent domain containing 4A
chr14_-_91884150 0.07 ENST00000553403.1
 CCDC88C
 coiled-coil domain containing 88C
chr5_+_43603229 0.07 ENST00000344920.4
ENST00000512996.2
 NNT
 nicotinamide nucleotide transhydrogenase
chr2_+_74685527 0.07 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
 WBP1
 WW domain binding protein 1
chr6_-_31632962 0.07 ENST00000456540.1
ENST00000445768.1
 GPANK1
 G patch domain and ankyrin repeats 1
chr5_-_157002775 0.07 ENST00000257527.4
 ADAM19
 ADAM metallopeptidase domain 19
chr4_+_76649797 0.07 ENST00000538159.1
ENST00000514213.2
 USO1
 USO1 vesicle transport factor
chr14_-_71107921 0.07 ENST00000553982.1
ENST00000500016.1
 CTD-2540L5.5
CTD-2540L5.6
 CTD-2540L5.5
CTD-2540L5.6
chr6_-_79944336 0.07 ENST00000344726.5
ENST00000275036.7
 HMGN3
 high mobility group nucleosomal binding domain 3
chr6_+_27114861 0.07 ENST00000377459.1
 HIST1H2AH
 histone cluster 1, H2ah
chr6_+_126240442 0.07 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
 NCOA7
 nuclear receptor coactivator 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.4 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.2 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0048675 axon extension(GO:0048675)
0.0 0.1 GO:0061030 axon target recognition(GO:0007412) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0070837 L-ascorbic acid transport(GO:0015882) dehydroascorbic acid transport(GO:0070837) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.0 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0033300 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) dehydroascorbic acid transporter activity(GO:0033300) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates