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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SOX11

Z-value: 0.37

Motif logo

Transcription factors associated with SOX11

Gene Symbol Gene ID Gene Info
ENSG00000176887.5 SOX11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX11hg19_v2_chr2_+_5832799_5832799-0.059.0e-01Click!

Activity profile of SOX11 motif

Sorted Z-values of SOX11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX11

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_47596287 0.52 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr5_+_140213815 0.34 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr4_-_90759440 0.32 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr5_+_140248518 0.32 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr6_-_116381918 0.30 ENST00000606080.1
FRK
fyn-related kinase
chr5_+_147582387 0.29 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr5_+_55149150 0.25 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr6_-_11779174 0.23 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr6_-_11779014 0.22 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr8_+_104831472 0.22 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr5_+_147582348 0.20 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr3_-_112564797 0.19 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr1_-_120935894 0.19 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr10_-_5446786 0.15 ENST00000479328.1
ENST00000380419.3
TUBAL3
tubulin, alpha-like 3
chr7_-_82792215 0.15 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr4_-_22444733 0.14 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr2_+_207804278 0.14 ENST00000272852.3
CPO
carboxypeptidase O
chr5_+_140207536 0.13 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr1_-_24469602 0.13 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chrX_-_132231123 0.12 ENST00000511190.1
USP26
ubiquitin specific peptidase 26
chr4_+_183164574 0.12 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr21_+_43619796 0.11 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr12_+_41221794 0.11 ENST00000547849.1
CNTN1
contactin 1
chr3_+_112930306 0.11 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chrX_-_32173579 0.11 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr9_+_71986182 0.11 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr4_+_159443090 0.10 ENST00000343542.5
ENST00000470033.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr8_+_104831554 0.10 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_5238793 0.10 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr6_-_47277634 0.09 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr15_-_99791413 0.08 ENST00000394129.2
ENST00000558663.1
ENST00000394135.3
ENST00000561365.1
ENST00000560279.1
TTC23
tetratricopeptide repeat domain 23
chrX_+_107288239 0.08 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr10_-_90611566 0.08 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr11_+_7110165 0.07 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chr9_-_95166841 0.07 ENST00000262551.4
OGN
osteoglycin
chr7_-_92855762 0.07 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr17_+_35732955 0.07 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr16_+_67261008 0.07 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr17_+_35732916 0.07 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr20_-_13971255 0.07 ENST00000284951.5
ENST00000378072.5
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr8_+_41386725 0.07 ENST00000276533.3
ENST00000520710.1
ENST00000518671.1
GINS4
GINS complex subunit 4 (Sld5 homolog)
chrX_-_15619076 0.07 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr18_+_22040620 0.07 ENST00000426880.2
HRH4
histamine receptor H4
chr3_+_112930387 0.06 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr6_-_32557610 0.06 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr18_+_22040593 0.06 ENST00000256906.4
HRH4
histamine receptor H4
chr2_-_73869508 0.06 ENST00000272425.3
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr7_-_81399411 0.06 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_+_107288197 0.06 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr19_+_50094866 0.06 ENST00000418929.2
PRR12
proline rich 12
chr1_+_196621156 0.06 ENST00000359637.2
CFH
complement factor H
chr17_-_39324424 0.06 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr15_+_45028719 0.05 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69
tripartite motif containing 69
chr15_+_45028753 0.05 ENST00000338264.4
TRIM69
tripartite motif containing 69
chr12_-_11287243 0.05 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr1_-_205744205 0.05 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr1_-_111061797 0.05 ENST00000369771.2
KCNA10
potassium voltage-gated channel, shaker-related subfamily, member 10
chr5_-_115872142 0.05 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_-_107777208 0.05 ENST00000398258.3
CD47
CD47 molecule
chr8_+_41386761 0.05 ENST00000523277.2
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr6_-_49604545 0.04 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr10_-_24770632 0.04 ENST00000596413.1
AL353583.1
AL353583.1
chr1_-_205744574 0.04 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr1_+_196621002 0.04 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr2_-_219157250 0.04 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr11_+_22688150 0.04 ENST00000454584.2
GAS2
growth arrest-specific 2
chr4_+_88754069 0.04 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr4_+_72204755 0.04 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr6_-_99873145 0.04 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr3_+_113616317 0.04 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr17_-_10017864 0.04 ENST00000323816.4
GAS7
growth arrest-specific 7
chr6_+_26183958 0.04 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr5_+_175085033 0.04 ENST00000377291.2
HRH2
histamine receptor H2
chr2_+_102927962 0.04 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr4_-_71532339 0.04 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_+_96949319 0.04 ENST00000554706.1
AK7
adenylate kinase 7
chr2_+_105050794 0.04 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr4_+_88754113 0.04 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr6_+_30585486 0.04 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chrX_+_24483338 0.04 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr4_+_95972822 0.03 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr17_+_47448102 0.03 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr9_+_12775011 0.03 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr6_-_76072719 0.03 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr15_-_78913628 0.03 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr1_+_204839959 0.03 ENST00000404076.1
NFASC
neurofascin
chrX_+_27826107 0.03 ENST00000356790.2
MAGEB10
melanoma antigen family B, 10
chr1_+_149754227 0.03 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr11_-_64684672 0.03 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr18_+_56887381 0.03 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
GRP
gastrin-releasing peptide
chr5_+_53813536 0.03 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
SNX18
sorting nexin 18
chr2_+_169658928 0.03 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr2_-_178128250 0.03 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr6_-_52705641 0.03 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chrX_-_100548045 0.03 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr2_+_169659121 0.03 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr3_-_133380731 0.03 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr8_+_118147498 0.03 ENST00000519688.1
ENST00000456015.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr14_+_39703084 0.02 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr15_+_69857515 0.02 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr4_-_105416039 0.02 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr7_-_25268104 0.02 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr11_+_57425209 0.02 ENST00000533905.1
ENST00000525602.1
ENST00000302731.4
CLP1
cleavage and polyadenylation factor I subunit 1
chr13_-_99630233 0.02 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr5_+_173472607 0.02 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr2_+_27799389 0.02 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr9_-_114521783 0.02 ENST00000394779.3
ENST00000394777.4
C9orf84
chromosome 9 open reading frame 84
chr3_-_49967292 0.02 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr20_+_18794370 0.02 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr3_+_130279178 0.02 ENST00000358511.6
ENST00000453409.2
COL6A6
collagen, type VI, alpha 6
chr11_+_92085262 0.02 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr7_+_50348268 0.02 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr4_+_169013666 0.02 ENST00000359299.3
ANXA10
annexin A10
chr3_+_178253993 0.01 ENST00000420517.2
ENST00000452583.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_+_39703112 0.01 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chrM_+_8527 0.01 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr1_+_214776516 0.01 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chrX_+_26156460 0.01 ENST00000325250.1
MAGEB18
melanoma antigen family B, 18
chr7_-_81399329 0.01 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_121944491 0.01 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr3_-_55001115 0.01 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr20_+_32250079 0.01 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr21_-_45671014 0.01 ENST00000436357.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr17_-_72772462 0.01 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr3_-_87325612 0.01 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr20_+_35807512 0.01 ENST00000373622.5
RPN2
ribophorin II
chr10_-_25305011 0.01 ENST00000331161.4
ENST00000376363.1
ENKUR
enkurin, TRPC channel interacting protein
chr15_-_79383102 0.01 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr20_-_7921090 0.01 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr8_+_19796381 0.01 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL
lipoprotein lipase
chr10_+_118350522 0.01 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr8_-_54752406 0.01 ENST00000520188.1
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chrM_+_7586 0.01 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr8_-_72274095 0.01 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr21_+_17792672 0.01 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_133055815 0.01 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chrX_+_130192318 0.01 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr3_-_87325728 0.01 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr8_-_623547 0.01 ENST00000522893.1
ERICH1
glutamate-rich 1
chr2_-_71222466 0.01 ENST00000606025.1
AC007040.11
Uncharacterized protein
chr16_+_67381289 0.01 ENST00000435835.3
LRRC36
leucine rich repeat containing 36
chr9_-_21142144 0.01 ENST00000380229.2
IFNW1
interferon, omega 1
chr2_-_20251744 0.01 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr12_+_28410128 0.00 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr17_+_38474489 0.00 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr16_+_67381263 0.00 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
LRRC36
leucine rich repeat containing 36
chr15_-_64673665 0.00 ENST00000300035.4
KIAA0101
KIAA0101
chr6_-_49712147 0.00 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr3_-_57678772 0.00 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr5_+_169780485 0.00 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr4_+_159442878 0.00 ENST00000307765.5
ENST00000423548.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr20_-_35807741 0.00 ENST00000434295.1
ENST00000441008.2
ENST00000400441.3
ENST00000343811.4
MROH8
maestro heat-like repeat family member 8
chr6_-_49712123 0.00 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr1_+_207038699 0.00 ENST00000367098.1
IL20
interleukin 20
chr1_-_150669604 0.00 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chrX_-_13835147 0.00 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr3_+_113251143 0.00 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr12_+_50794592 0.00 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
LARP4
La ribonucleoprotein domain family, member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)