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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SOX13_SOX12

Z-value: 0.63

Motif logo

Transcription factors associated with SOX13_SOX12

Gene Symbol Gene ID Gene Info
ENSG00000143842.10 SOX13
ENSG00000177732.6 SOX12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX12hg19_v2_chr20_+_306221_306239-0.541.6e-01Click!
SOX13hg19_v2_chr1_+_204042723_2040427840.098.3e-01Click!

Activity profile of SOX13_SOX12 motif

Sorted Z-values of SOX13_SOX12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX13_SOX12

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_8803128 1.15 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr10_+_118187379 1.15 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr1_+_153003671 1.13 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr12_-_8815215 0.93 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr12_-_8815299 0.78 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr19_+_35609380 0.74 ENST00000604621.1
FXYD3
FXYD domain containing ion transport regulator 3
chr5_+_147582387 0.69 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr1_+_77333117 0.65 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr1_-_153363452 0.63 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr10_-_105845674 0.58 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr6_-_136847610 0.57 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr5_+_140235469 0.56 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr8_+_32579341 0.51 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr18_+_61254534 0.48 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr12_-_8814669 0.47 ENST00000535411.1
ENST00000540087.1
MFAP5
microfibrillar associated protein 5
chr2_+_207804278 0.47 ENST00000272852.3
CPO
carboxypeptidase O
chr12_-_8815404 0.44 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr5_+_140213815 0.43 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr3_+_98699880 0.41 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr11_-_51412448 0.41 ENST00000319760.6
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr11_-_102651343 0.39 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr2_-_216878305 0.38 ENST00000263268.6
MREG
melanoregulin
chr5_+_35856951 0.38 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr3_+_111717600 0.37 ENST00000273368.4
TAGLN3
transgelin 3
chr4_-_15939963 0.37 ENST00000259988.2
FGFBP1
fibroblast growth factor binding protein 1
chr7_-_121944491 0.35 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr2_-_238499303 0.34 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr21_+_43619796 0.34 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr5_+_140248518 0.34 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr2_+_102927962 0.33 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr11_+_7110165 0.33 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chr3_+_111717511 0.33 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr18_+_61254570 0.33 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr12_+_4385230 0.32 ENST00000536537.1
CCND2
cyclin D2
chr1_+_161677034 0.32 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chr5_+_140220769 0.32 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr1_+_152975488 0.31 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr5_+_140261703 0.31 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr5_+_147582348 0.30 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr3_-_112564797 0.30 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr10_+_32873190 0.29 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr12_-_28125638 0.28 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr4_+_77356248 0.28 ENST00000296043.6
SHROOM3
shroom family member 3
chr12_-_11287243 0.28 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr5_-_82969405 0.27 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr2_+_131769256 0.25 ENST00000355771.3
ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
chr12_+_51317788 0.25 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr6_-_136788001 0.25 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr4_+_53728457 0.25 ENST00000248706.3
RASL11B
RAS-like, family 11, member B
chr11_+_128563652 0.24 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_+_9102632 0.24 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr1_-_153433120 0.24 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr9_-_39239171 0.23 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr2_-_238499131 0.23 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr7_+_142364193 0.23 ENST00000390397.2
TRBV24-1
T cell receptor beta variable 24-1
chr7_+_116660246 0.23 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr6_-_11779014 0.23 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr9_-_140196703 0.22 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr18_+_47088401 0.22 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr3_+_32433154 0.22 ENST00000334983.5
ENST00000349718.4
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr2_-_238499337 0.22 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr12_-_11150474 0.22 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr3_+_32433363 0.22 ENST00000465248.1
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr1_+_161676739 0.21 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr1_+_161676983 0.21 ENST00000367957.2
FCRLA
Fc receptor-like A
chr6_+_106534192 0.21 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr14_+_22739823 0.21 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr5_+_121465207 0.21 ENST00000296600.4
ZNF474
zinc finger protein 474
chr4_+_100737954 0.21 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr11_+_128563948 0.21 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_+_102504651 0.20 ENST00000251808.3
ENST00000521085.1
GRHL2
grainyhead-like 2 (Drosophila)
chr6_-_139613269 0.20 ENST00000358430.3
TXLNB
taxilin beta
chr19_-_14785674 0.20 ENST00000253673.5
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr14_+_22580233 0.20 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chr19_-_14785622 0.20 ENST00000443157.2
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chrX_+_107288239 0.20 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr6_+_125540951 0.20 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr18_+_42260861 0.19 ENST00000282030.5
SETBP1
SET binding protein 1
chr7_-_41742697 0.19 ENST00000242208.4
INHBA
inhibin, beta A
chr17_+_56315787 0.19 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr11_+_34654011 0.19 ENST00000531794.1
EHF
ets homologous factor
chrX_+_107288197 0.19 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr19_-_14785698 0.18 ENST00000344373.4
ENST00000595472.1
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr1_+_13910194 0.18 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr1_-_116383322 0.18 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr12_-_10962767 0.18 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr6_+_12290586 0.18 ENST00000379375.5
EDN1
endothelin 1
chr6_-_11779174 0.18 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr19_-_43099070 0.18 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr4_-_74864386 0.18 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr10_-_61513146 0.17 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chr1_-_152297679 0.17 ENST00000368799.1
FLG
filaggrin
chr1_-_153013588 0.17 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr9_+_22446814 0.17 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr2_+_90153696 0.17 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr10_-_123357910 0.16 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
FGFR2
fibroblast growth factor receptor 2
chr4_+_74301880 0.16 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr2_-_201599892 0.16 ENST00000452787.1
AC007163.3
AC007163.3
chr12_+_25205446 0.16 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr10_-_116444371 0.16 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr11_-_79151695 0.16 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr10_+_5238793 0.16 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr15_-_99791413 0.16 ENST00000394129.2
ENST00000558663.1
ENST00000394135.3
ENST00000561365.1
ENST00000560279.1
TTC23
tetratricopeptide repeat domain 23
chr19_-_42192096 0.16 ENST00000602225.1
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr4_+_187148556 0.15 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr12_+_21168630 0.15 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr21_-_34186006 0.15 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr11_-_59950486 0.15 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr17_+_56315936 0.15 ENST00000543544.1
LPO
lactoperoxidase
chr4_-_143226979 0.15 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr19_+_4402659 0.15 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr18_-_70211691 0.15 ENST00000269503.4
CBLN2
cerebellin 2 precursor
chr11_+_55029628 0.14 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr4_-_143227088 0.14 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_-_36406750 0.14 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
KIAA0895
KIAA0895
chr16_+_2867228 0.14 ENST00000005995.3
ENST00000574813.1
PRSS21
protease, serine, 21 (testisin)
chr19_+_41281282 0.14 ENST00000263369.3
MIA
melanoma inhibitory activity
chr8_-_124054587 0.14 ENST00000259512.4
DERL1
derlin 1
chr10_-_10836919 0.14 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr6_-_155776966 0.14 ENST00000159060.2
NOX3
NADPH oxidase 3
chr4_-_77328458 0.14 ENST00000388914.3
ENST00000434846.2
CCDC158
coiled-coil domain containing 158
chr20_-_5426332 0.13 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chr13_-_46716969 0.13 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_34610962 0.13 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr2_+_90198535 0.13 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr7_-_105162652 0.13 ENST00000356362.2
ENST00000469408.1
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr7_-_82792215 0.12 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chrX_-_32173579 0.12 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr12_+_101988774 0.12 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr1_+_153388993 0.12 ENST00000368729.4
S100A7A
S100 calcium binding protein A7A
chr17_+_53828333 0.12 ENST00000268896.5
PCTP
phosphatidylcholine transfer protein
chr15_-_76005170 0.12 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr3_-_32544900 0.12 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr15_+_88120158 0.12 ENST00000560153.1
LINC00052
long intergenic non-protein coding RNA 52
chr6_-_9939552 0.12 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr1_-_153029980 0.12 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr21_-_34185989 0.12 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr14_+_50291993 0.12 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr11_-_8964580 0.11 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr6_+_150920999 0.11 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_+_197577841 0.11 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr14_-_106330458 0.11 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr2_-_9143786 0.11 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr12_+_25205666 0.11 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr10_+_49917751 0.11 ENST00000325239.5
ENST00000413659.2
WDFY4
WDFY family member 4
chr9_-_21351377 0.11 ENST00000380210.1
IFNA6
interferon, alpha 6
chr11_+_93479588 0.11 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr6_-_119256311 0.11 ENST00000316316.6
MCM9
minichromosome maintenance complex component 9
chr16_+_2867164 0.11 ENST00000455114.1
ENST00000450020.3
PRSS21
protease, serine, 21 (testisin)
chr11_+_73661364 0.11 ENST00000339764.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr13_+_32313658 0.11 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr15_+_80733570 0.10 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr11_-_89653576 0.10 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr11_-_10829851 0.10 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr7_+_99195677 0.10 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chr1_-_36107445 0.10 ENST00000373237.3
PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr10_-_61513201 0.10 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr2_+_118572226 0.10 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr4_+_95128996 0.10 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr19_+_42212501 0.10 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr18_+_55888767 0.10 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr20_-_50384864 0.10 ENST00000311637.5
ENST00000402822.1
ATP9A
ATPase, class II, type 9A
chr12_-_10151773 0.10 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr19_+_41281060 0.10 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr17_+_35851570 0.10 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr3_-_123339343 0.10 ENST00000578202.1
MYLK
myosin light chain kinase
chr7_-_38305279 0.10 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr21_+_25801041 0.10 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr14_+_21387508 0.10 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr6_-_28411241 0.10 ENST00000289788.4
ZSCAN23
zinc finger and SCAN domain containing 23
chr3_+_47866490 0.10 ENST00000457607.1
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr18_-_52989217 0.10 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_104817919 0.09 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_+_59480899 0.09 ENST00000300150.7
STX3
syntaxin 3
chr12_-_31479045 0.09 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr12_-_50616382 0.09 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr6_-_116381918 0.09 ENST00000606080.1
FRK
fyn-related kinase
chr14_+_56584414 0.09 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr11_+_33563821 0.09 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr12_+_20968608 0.09 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr11_-_59950519 0.09 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr12_+_48876275 0.09 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr14_+_73563735 0.09 ENST00000532192.1
RBM25
RNA binding motif protein 25
chrX_-_15619076 0.09 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr5_+_44809027 0.09 ENST00000507110.1
MRPS30
mitochondrial ribosomal protein S30
chr12_+_40787194 0.09 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr6_-_25830785 0.09 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chrX_-_33229636 0.09 ENST00000357033.4
DMD
dystrophin
chr4_+_154622652 0.09 ENST00000260010.6
TLR2
toll-like receptor 2
chr1_-_158656488 0.09 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr1_+_87012753 0.09 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr8_+_104831472 0.09 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr3_+_171561127 0.09 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr4_+_95128748 0.09 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chrX_+_105192423 0.08 ENST00000540278.1
NRK
Nik related kinase
chr7_+_107220660 0.08 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr1_-_225616515 0.08 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr2_+_168725458 0.08 ENST00000392690.3
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_-_79383102 0.08 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr4_+_100432161 0.08 ENST00000326581.4
ENST00000514652.1
C4orf17
chromosome 4 open reading frame 17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 3.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.8 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.2 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.2 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.7 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.2 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.0 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 1.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.0 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0060541 lung development(GO:0030324) respiratory system development(GO:0060541)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.0 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0098736 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0035407 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) histone H3-T11 phosphorylation(GO:0035407)
0.0 0.0 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.0 0.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.0 GO:0097447 dendritic tree(GO:0097447)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix