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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SOX3_SOX2

Z-value: 0.05

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Transcription factors associated with SOX3_SOX2

Gene Symbol Gene ID Gene Info
SOX3
ENSG00000134595.6 SOX3
SOX2
ENSG00000181449.2 SOX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX3hg19_v2_chrX_-_139587225_139587234-0.883.9e-03Click!
SOX2hg19_v2_chr3_+_181429704_1814297220.696.0e-02Click!

Activity profile of SOX3_SOX2 motif

Sorted Z-values of SOX3_SOX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX3_SOX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_138453606 1.15 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
 PCDH18
 protocadherin 18
chr4_-_138453559 0.98 ENST00000511115.1
 PCDH18
 protocadherin 18
chr6_+_72596604 0.80 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
 RIMS1
 regulating synaptic membrane exocytosis 1
chr8_-_124553437 0.73 ENST00000517956.1
ENST00000443022.2
 FBXO32
 F-box protein 32
chr4_-_186877502 0.65 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
 SORBS2
 sorbin and SH3 domain containing 2
chr22_+_27053422 0.62 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
 MIAT
 myocardial infarction associated transcript (non-protein coding)
chr8_-_22550815 0.58 ENST00000317216.2
 EGR3
 early growth response 3
chr16_-_4987065 0.57 ENST00000590782.2
ENST00000345988.2
 PPL
 periplakin
chr4_-_186732048 0.56 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
 SORBS2
 sorbin and SH3 domain containing 2
chr9_-_131940526 0.53 ENST00000372491.2
 IER5L
 immediate early response 5-like
chr2_+_210444142 0.51 ENST00000360351.4
ENST00000361559.4
 MAP2
 microtubule-associated protein 2
chr11_-_94965667 0.51 ENST00000542176.1
ENST00000278499.2
 SESN3
 sestrin 3
chr3_-_114343768 0.48 ENST00000393785.2
 ZBTB20
 zinc finger and BTB domain containing 20
chr9_+_101705893 0.48 ENST00000375001.3
 COL15A1
 collagen, type XV, alpha 1
chr8_+_104384616 0.47 ENST00000520337.1
 CTHRC1
 collagen triple helix repeat containing 1
chr6_+_30848557 0.46 ENST00000460944.2
ENST00000324771.8
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr1_+_215256467 0.44 ENST00000391894.2
ENST00000444842.2
 KCNK2
 potassium channel, subfamily K, member 2
chr3_-_18466026 0.44 ENST00000417717.2
 SATB1
 SATB homeobox 1
chr22_+_27053190 0.42 ENST00000439738.1
ENST00000422403.1
ENST00000436238.1
ENST00000425476.1
ENST00000455640.1
ENST00000451141.1
ENST00000452429.1
ENST00000423278.1
 MIAT
 myocardial infarction associated transcript (non-protein coding)
chr9_-_123476612 0.42 ENST00000426959.1
 MEGF9
 multiple EGF-like-domains 9
chr9_-_123476719 0.41 ENST00000373930.3
 MEGF9
 multiple EGF-like-domains 9
chr4_+_62067860 0.41 ENST00000514591.1
 LPHN3
 latrophilin 3
chr20_-_39317868 0.40 ENST00000373313.2
 MAFB
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr19_+_45409011 0.39 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
 APOE
 apolipoprotein E
chr15_-_93632421 0.39 ENST00000329082.7
 RGMA
 repulsive guidance molecule family member a
chrX_+_55744228 0.38 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr1_+_145727681 0.38 ENST00000417171.1
ENST00000451928.2
 PDZK1
 PDZ domain containing 1
chr7_+_16793160 0.38 ENST00000262067.4
 TSPAN13
 tetraspanin 13
chr4_+_95679072 0.38 ENST00000515059.1
 BMPR1B
 bone morphogenetic protein receptor, type IB
chrX_+_55744166 0.38 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chr4_-_159080806 0.37 ENST00000590648.1
 FAM198B
 family with sequence similarity 198, member B
chr11_-_111794446 0.36 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr3_-_48470838 0.36 ENST00000358459.4
ENST00000358536.4
 PLXNB1
 plexin B1
chr1_-_32801825 0.36 ENST00000329421.7
 MARCKSL1
 MARCKS-like 1
chr4_+_41614720 0.36 ENST00000509277.1
 LIMCH1
 LIM and calponin homology domains 1
chr9_-_95298314 0.35 ENST00000344604.5
ENST00000375540.1
 ECM2
 extracellular matrix protein 2, female organ and adipocyte specific
chr14_-_22005018 0.35 ENST00000546363.1
 SALL2
 spalt-like transcription factor 2
chr11_-_111781554 0.35 ENST00000526167.1
ENST00000528961.1
 CRYAB
 crystallin, alpha B
chr1_-_156828810 0.35 ENST00000368195.3
 INSRR
 insulin receptor-related receptor
chr6_+_72596406 0.34 ENST00000491071.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr10_-_70092671 0.34 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
 PBLD
 phenazine biosynthesis-like protein domain containing
chr8_-_17579726 0.33 ENST00000381861.3
 MTUS1
 microtubule associated tumor suppressor 1
chr12_-_7281469 0.33 ENST00000542370.1
ENST00000266560.3
 RBP5
 retinol binding protein 5, cellular
chr10_+_60759378 0.33 ENST00000432535.1
 LINC00844
 long intergenic non-protein coding RNA 844
chr1_+_200993071 0.33 ENST00000446333.1
ENST00000458003.1
 RP11-168O16.1
 RP11-168O16.1
chr1_+_33722080 0.33 ENST00000483388.1
ENST00000539719.1
 ZNF362
 zinc finger protein 362
chr15_-_52944231 0.33 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr1_+_11751748 0.32 ENST00000294485.5
 DRAXIN
 dorsal inhibitory axon guidance protein
chr4_-_2264015 0.32 ENST00000337190.2
 MXD4
 MAX dimerization protein 4
chr5_-_175964366 0.32 ENST00000274811.4
 RNF44
 ring finger protein 44
chr11_-_111781610 0.32 ENST00000525823.1
 CRYAB
 crystallin, alpha B
chr3_-_58563094 0.31 ENST00000464064.1
 FAM107A
 family with sequence similarity 107, member A
chr11_-_111781454 0.31 ENST00000533280.1
 CRYAB
 crystallin, alpha B
chr15_-_82338460 0.31 ENST00000558133.1
ENST00000329713.4
 MEX3B
 mex-3 RNA binding family member B
chr15_+_22382382 0.31 ENST00000328795.4
 OR4N4
 olfactory receptor, family 4, subfamily N, member 4
chrX_+_84499081 0.30 ENST00000276123.3
 ZNF711
 zinc finger protein 711
chr16_-_11730213 0.30 ENST00000576334.1
ENST00000574848.1
 LITAF
 lipopolysaccharide-induced TNF factor
chr1_+_197886461 0.29 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
 LHX9
 LIM homeobox 9
chr8_-_21988558 0.29 ENST00000312841.8
 HR
 hair growth associated
chr7_-_19813192 0.29 ENST00000422233.1
ENST00000433641.1
 TMEM196
 transmembrane protein 196
chr19_-_20844343 0.29 ENST00000595405.1
 ZNF626
 zinc finger protein 626
chr11_+_57365150 0.29 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
 SERPING1
 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr7_+_20370746 0.29 ENST00000222573.4
 ITGB8
 integrin, beta 8
chr2_-_1748214 0.29 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
 PXDN
 peroxidasin homolog (Drosophila)
chr3_-_87040233 0.28 ENST00000398399.2
 VGLL3
 vestigial like 3 (Drosophila)
chr2_-_175869936 0.28 ENST00000409900.3
 CHN1
 chimerin 1
chr2_+_210517895 0.28 ENST00000447185.1
 MAP2
 microtubule-associated protein 2
chr9_+_139874683 0.27 ENST00000444903.1
 PTGDS
 prostaglandin D2 synthase 21kDa (brain)
chr6_+_112375275 0.27 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
 WISP3
 WNT1 inducible signaling pathway protein 3
chr17_-_9940058 0.27 ENST00000585266.1
 GAS7
 growth arrest-specific 7
chrX_-_142722897 0.27 ENST00000338017.4
 SLITRK4
 SLIT and NTRK-like family, member 4
chr4_-_175443943 0.27 ENST00000296522.6
 HPGD
 hydroxyprostaglandin dehydrogenase 15-(NAD)
chr17_+_7608511 0.27 ENST00000226091.2
 EFNB3
 ephrin-B3
chr3_+_39509070 0.26 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
 MOBP
 myelin-associated oligodendrocyte basic protein
chr20_-_50418947 0.26 ENST00000371539.3
 SALL4
 spalt-like transcription factor 4
chr21_+_27011584 0.26 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
 JAM2
 junctional adhesion molecule 2
chr17_+_1674982 0.25 ENST00000572048.1
ENST00000573763.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr20_-_50418972 0.25 ENST00000395997.3
 SALL4
 spalt-like transcription factor 4
chr20_-_50419055 0.25 ENST00000217086.4
 SALL4
 spalt-like transcription factor 4
chrX_+_80457442 0.25 ENST00000373212.5
 SH3BGRL
 SH3 domain binding glutamic acid-rich protein like
chr12_+_31079652 0.25 ENST00000546076.1
ENST00000535215.1
ENST00000544427.1
ENST00000261177.9
 TSPAN11
 tetraspanin 11
chr1_-_156217829 0.25 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
 PAQR6
 progestin and adipoQ receptor family member VI
chr1_+_164529004 0.25 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
 PBX1
 pre-B-cell leukemia homeobox 1
chr19_-_55691377 0.25 ENST00000589172.1
 SYT5
 synaptotagmin V
chr14_+_96505659 0.25 ENST00000555004.1
 C14orf132
 chromosome 14 open reading frame 132
chr6_-_128841503 0.25 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
 PTPRK
 protein tyrosine phosphatase, receptor type, K
chr1_-_156217822 0.24 ENST00000368270.1
 PAQR6
 progestin and adipoQ receptor family member VI
chr4_+_86699834 0.24 ENST00000395183.2
 ARHGAP24
 Rho GTPase activating protein 24
chr8_-_108510224 0.24 ENST00000517746.1
ENST00000297450.3
 ANGPT1
 angiopoietin 1
chr12_+_80750134 0.24 ENST00000546620.1
 OTOGL
 otogelin-like
chr5_+_140593509 0.24 ENST00000341948.4
 PCDHB13
 protocadherin beta 13
chr4_-_90757364 0.24 ENST00000508895.1
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr1_-_3528034 0.24 ENST00000356575.4
 MEGF6
 multiple EGF-like-domains 6
chr14_-_91884115 0.24 ENST00000389857.6
 CCDC88C
 coiled-coil domain containing 88C
chr1_-_161015752 0.23 ENST00000435396.1
ENST00000368021.3
 USF1
 upstream transcription factor 1
chr4_-_5890145 0.23 ENST00000397890.2
 CRMP1
 collapsin response mediator protein 1
chr3_+_149689066 0.23 ENST00000593416.1
 AC117395.1
 LOC646903 protein; Uncharacterized protein
chr1_-_156217875 0.23 ENST00000292291.5
 PAQR6
 progestin and adipoQ receptor family member VI
chr2_+_105050794 0.23 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
 AC013402.2
 long intergenic non-protein coding RNA 1102
chr2_+_210444748 0.23 ENST00000392194.1
 MAP2
 microtubule-associated protein 2
chr16_-_31085033 0.23 ENST00000414399.1
 ZNF668
 zinc finger protein 668
chr5_+_15500280 0.23 ENST00000504595.1
 FBXL7
 F-box and leucine-rich repeat protein 7
chr10_-_70092635 0.23 ENST00000309049.4
 PBLD
 phenazine biosynthesis-like protein domain containing
chr5_-_39425290 0.22 ENST00000545653.1
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr18_+_6729698 0.22 ENST00000383472.4
 ARHGAP28
 Rho GTPase activating protein 28
chr11_-_117747434 0.22 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
 FXYD6
 FXYD domain containing ion transport regulator 6
chr6_-_46459099 0.22 ENST00000371374.1
 RCAN2
 regulator of calcineurin 2
chr8_-_48651648 0.22 ENST00000408965.3
 CEBPD
 CCAAT/enhancer binding protein (C/EBP), delta
chr5_+_140235469 0.22 ENST00000506939.2
ENST00000307360.5
 PCDHA10
 protocadherin alpha 10
chr5_+_148960931 0.22 ENST00000333677.6
 ARHGEF37
 Rho guanine nucleotide exchange factor (GEF) 37
chr3_-_114790179 0.22 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr12_+_94542459 0.22 ENST00000258526.4
 PLXNC1
 plexin C1
chr2_+_30454390 0.22 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
 LBH
 limb bud and heart development
chr6_-_24877490 0.22 ENST00000540914.1
ENST00000378023.4
 FAM65B
 family with sequence similarity 65, member B
chr1_-_46598371 0.22 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr16_-_28550348 0.22 ENST00000324873.6
 NUPR1
 nuclear protein, transcriptional regulator, 1
chr7_+_141463897 0.22 ENST00000247879.2
 TAS2R3
 taste receptor, type 2, member 3
chr6_+_126240442 0.22 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
 NCOA7
 nuclear receptor coactivator 7
chr5_-_39425222 0.21 ENST00000320816.6
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr3_+_44596679 0.21 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
 ZKSCAN7
 zinc finger with KRAB and SCAN domains 7
chr14_+_91580777 0.21 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
 C14orf159
 chromosome 14 open reading frame 159
chrX_+_100333709 0.21 ENST00000372930.4
 TMEM35
 transmembrane protein 35
chr19_-_7553852 0.21 ENST00000593547.1
 PEX11G
 peroxisomal biogenesis factor 11 gamma
chr10_+_72972281 0.21 ENST00000335350.6
 UNC5B
 unc-5 homolog B (C. elegans)
chr14_+_91580708 0.21 ENST00000518868.1
 C14orf159
 chromosome 14 open reading frame 159
chr1_-_3447967 0.21 ENST00000294599.4
 MEGF6
 multiple EGF-like-domains 6
chr1_+_144339738 0.21 ENST00000538264.1
 AL592284.1
 Protein LOC642441
chr1_-_1243392 0.20 ENST00000354700.5
 ACAP3
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr4_-_90756769 0.20 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_175443788 0.20 ENST00000541923.1
 HPGD
 hydroxyprostaglandin dehydrogenase 15-(NAD)
chr14_-_73493784 0.20 ENST00000553891.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr3_+_133118839 0.20 ENST00000302334.2
 BFSP2
 beaded filament structural protein 2, phakinin
chr22_-_32555275 0.20 ENST00000382097.3
 C22orf42
 chromosome 22 open reading frame 42
chr14_+_91581011 0.20 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
 C14orf159
 chromosome 14 open reading frame 159
chr7_+_70597109 0.19 ENST00000333538.5
 WBSCR17
 Williams-Beuren syndrome chromosome region 17
chr12_+_31477250 0.19 ENST00000313737.4
 AC024940.1
 AC024940.1
chr14_+_95078714 0.19 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
 SERPINA3
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_10588539 0.19 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
 KLRC2
NKG2-E
 killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr11_-_10829851 0.19 ENST00000532082.1
 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
chr1_-_153283194 0.19 ENST00000290722.1
 PGLYRP3
 peptidoglycan recognition protein 3
chrX_+_102469997 0.18 ENST00000372695.5
ENST00000372691.3
 BEX4
 brain expressed, X-linked 4
chr6_+_89790490 0.18 ENST00000336032.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr3_+_183353356 0.18 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
 KLHL24
 kelch-like family member 24
chr8_-_93115445 0.18 ENST00000523629.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_89790459 0.18 ENST00000369472.1
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr11_+_1889880 0.18 ENST00000405957.2
 LSP1
 lymphocyte-specific protein 1
chr2_+_74685527 0.18 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
 WBP1
 WW domain binding protein 1
chrX_+_69488174 0.18 ENST00000480877.2
ENST00000307959.8
 ARR3
 arrestin 3, retinal (X-arrestin)
chr3_-_48700310 0.18 ENST00000164024.4
ENST00000544264.1
 CELSR3
 cadherin, EGF LAG seven-pass G-type receptor 3
chr5_-_39425068 0.18 ENST00000515700.1
ENST00000339788.6
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_+_181845298 0.18 ENST00000410062.4
 UBE2E3
 ubiquitin-conjugating enzyme E2E 3
chr13_+_31506818 0.18 ENST00000380473.3
 TEX26
 testis expressed 26
chr4_-_175443484 0.18 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
 HPGD
 hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_+_15480828 0.18 ENST00000389652.5
 CC2D2A
 coiled-coil and C2 domain containing 2A
chr14_-_73493825 0.18 ENST00000318876.5
ENST00000556143.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr15_+_34310428 0.18 ENST00000557872.1
 CHRM5
 cholinergic receptor, muscarinic 5
chr4_+_41258786 0.18 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chrX_-_13956497 0.18 ENST00000398361.3
 GPM6B
 glycoprotein M6B
chr8_-_120685608 0.17 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_150866779 0.17 ENST00000370353.3
 PRRG3
 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr3_+_39509163 0.17 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
 MOBP
 myelin-associated oligodendrocyte basic protein
chr2_-_238499303 0.17 ENST00000409576.1
 RAB17
 RAB17, member RAS oncogene family
chrX_+_103031421 0.17 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
 PLP1
 proteolipid protein 1
chr2_+_177015950 0.17 ENST00000306324.3
 HOXD4
 homeobox D4
chr11_-_2162468 0.17 ENST00000434045.2
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr1_+_244998602 0.17 ENST00000411948.2
 COX20
 COX20 cytochrome C oxidase assembly factor
chr3_-_116163830 0.17 ENST00000333617.4
 LSAMP
 limbic system-associated membrane protein
chr10_+_70320413 0.17 ENST00000373644.4
 TET1
 tet methylcytosine dioxygenase 1
chr12_-_95611149 0.17 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr1_-_161014731 0.17 ENST00000368020.1
 USF1
 upstream transcription factor 1
chr2_-_166060571 0.17 ENST00000360093.3
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr9_-_130712995 0.17 ENST00000373084.4
 FAM102A
 family with sequence similarity 102, member A
chrX_+_103031758 0.17 ENST00000303958.2
ENST00000361621.2
 PLP1
 proteolipid protein 1
chr22_+_30792846 0.17 ENST00000312932.9
ENST00000428195.1
 SEC14L2
 SEC14-like 2 (S. cerevisiae)
chr9_+_2622085 0.17 ENST00000382099.2
 VLDLR
 very low density lipoprotein receptor
chr13_-_28674693 0.16 ENST00000537084.1
ENST00000241453.7
ENST00000380982.4
 FLT3
 fms-related tyrosine kinase 3
chr17_+_4046462 0.16 ENST00000577075.2
ENST00000575251.1
ENST00000301391.3
 CYB5D2
 cytochrome b5 domain containing 2
chr12_+_133707204 0.16 ENST00000426665.2
 ZNF10
 zinc finger protein 10
chr1_+_164528866 0.16 ENST00000420696.2
 PBX1
 pre-B-cell leukemia homeobox 1
chr12_-_52887034 0.16 ENST00000330722.6
 KRT6A
 keratin 6A
chr1_-_108231101 0.16 ENST00000544443.1
ENST00000415432.2
 VAV3
 vav 3 guanine nucleotide exchange factor
chr16_+_57673430 0.16 ENST00000540164.2
ENST00000568531.1
 GPR56
 G protein-coupled receptor 56
chr2_+_223536428 0.16 ENST00000446656.3
 MOGAT1
 monoacylglycerol O-acyltransferase 1
chr12_+_95611569 0.16 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
 VEZT
 vezatin, adherens junctions transmembrane protein
chr16_-_74455290 0.16 ENST00000339953.5
 CLEC18B
 C-type lectin domain family 18, member B
chr2_-_166060552 0.16 ENST00000283254.7
ENST00000453007.1
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr20_+_30598231 0.16 ENST00000300415.8
ENST00000262659.8
 CCM2L
 cerebral cavernous malformation 2-like
chr10_-_49482907 0.16 ENST00000374201.3
ENST00000407470.4
 FRMPD2
 FERM and PDZ domain containing 2
chr7_-_99869799 0.16 ENST00000436886.2
 GATS
 GATS, stromal antigen 3 opposite strand
chr3_-_11623804 0.16 ENST00000451674.2
 VGLL4
 vestigial like 4 (Drosophila)
chr22_-_32341336 0.16 ENST00000248984.3
 C22orf24
 chromosome 22 open reading frame 24
chr16_+_54964740 0.16 ENST00000394636.4
 IRX5
 iroquois homeobox 5
chr1_-_1334685 0.16 ENST00000400809.3
ENST00000408918.4
 CCNL2
 cyclin L2
chr17_+_27920486 0.15 ENST00000394859.3
 ANKRD13B
 ankyrin repeat domain 13B
chr19_+_1491144 0.15 ENST00000233596.3
 REEP6
 receptor accessory protein 6
chr1_-_17307173 0.15 ENST00000438542.1
ENST00000375535.3
 MFAP2
 microfibrillar-associated protein 2
chr1_+_235491714 0.15 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
 GGPS1
 geranylgeranyl diphosphate synthase 1
chr2_+_111880242 0.15 ENST00000393252.3
 BCL2L11
 BCL2-like 11 (apoptosis facilitator)
chrX_-_139866723 0.15 ENST00000370532.2
 CDR1
 cerebellar degeneration-related protein 1, 34kDa
chr20_+_61448376 0.15 ENST00000343916.3
 COL9A3
 collagen, type IX, alpha 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 0.6 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.4 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.2 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 1.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.6 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.4 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.7 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.1 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.2 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.1 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.3 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:1904300 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.3 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.0 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 1.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0048525 negative regulation of viral process(GO:0048525)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.0 GO:0070662 mast cell proliferation(GO:0070662)
0.0 0.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.0 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 3.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0061183 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.1 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.0 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.0 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.0 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059) inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0060458 right lung development(GO:0060458)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0009615 response to virus(GO:0009615)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0 0.5 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.6 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.0 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.0 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.7 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL