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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for SREBF1_TFE3

Z-value: 0.20

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Transcription factors associated with SREBF1_TFE3

Gene Symbol Gene ID Gene Info
SREBF1
ENSG00000072310.12 SREBF1
TFE3
ENSG00000068323.12 TFE3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SREBF1hg19_v2_chr17_-_17740325_177403490.255.5e-01Click!
TFE3hg19_v2_chrX_-_48901012_489010500.029.6e-01Click!

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_1785139 0.92 ENST00000236671.2
 CTSD
 cathepsin D
chr4_-_100242549 0.77 ENST00000305046.8
ENST00000394887.3
 ADH1B
 alcohol dehydrogenase 1B (class I), beta polypeptide
chr17_+_39382900 0.74 ENST00000377721.3
ENST00000455970.2
 KRTAP9-2
 keratin associated protein 9-2
chrX_+_55744166 0.74 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chrX_+_55744228 0.73 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr17_-_66951474 0.67 ENST00000269080.2
 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
chr19_-_36545649 0.59 ENST00000292894.1
 THAP8
 THAP domain containing 8
chr17_-_6915646 0.56 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
 AC027763.2
 Uncharacterized protein
chr12_-_63328817 0.56 ENST00000228705.6
 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr15_+_44084040 0.50 ENST00000249786.4
 SERF2
 small EDRK-rich factor 2
chrX_+_103031758 0.48 ENST00000303958.2
ENST00000361621.2
 PLP1
 proteolipid protein 1
chr12_+_50355647 0.48 ENST00000293599.6
 AQP5
 aquaporin 5
chr7_+_99070527 0.47 ENST00000379724.3
 ZNF789
 zinc finger protein 789
chrX_-_100914781 0.46 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
 ARMCX2
 armadillo repeat containing, X-linked 2
chr20_-_44519839 0.44 ENST00000372518.4
 NEURL2
 neuralized E3 ubiquitin protein ligase 2
chr2_+_148778570 0.43 ENST00000407073.1
 MBD5
 methyl-CpG binding domain protein 5
chr20_+_44519948 0.41 ENST00000354880.5
ENST00000191018.5
 CTSA
 cathepsin A
chr12_+_90102729 0.41 ENST00000605386.1
 LINC00936
 long intergenic non-protein coding RNA 936
chr9_-_79307096 0.40 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
 PRUNE2
 prune homolog 2 (Drosophila)
chr1_+_221051699 0.40 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr9_-_19127474 0.39 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
 PLIN2
 perilipin 2
chr12_-_91539918 0.38 ENST00000548218.1
 DCN
 decorin
chr19_-_36545128 0.37 ENST00000538849.1
 THAP8
 THAP domain containing 8
chr22_+_31002779 0.37 ENST00000215838.3
 TCN2
 transcobalamin II
chr6_+_124125286 0.37 ENST00000368416.1
ENST00000368417.1
ENST00000546092.1
 NKAIN2
 Na+/K+ transporting ATPase interacting 2
chr22_+_31003133 0.37 ENST00000405742.3
 TCN2
 transcobalamin II
chr9_+_17579084 0.36 ENST00000380607.4
 SH3GL2
 SH3-domain GRB2-like 2
chr20_+_44520009 0.34 ENST00000607482.1
ENST00000372459.2
 CTSA
 cathepsin A
chr17_+_57408994 0.34 ENST00000312655.4
 YPEL2
 yippee-like 2 (Drosophila)
chr1_-_31845914 0.33 ENST00000373713.2
 FABP3
 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr5_-_172198190 0.33 ENST00000239223.3
 DUSP1
 dual specificity phosphatase 1
chr15_+_41913690 0.33 ENST00000563576.1
 MGA
 MGA, MAX dimerization protein
chr6_-_33385854 0.33 ENST00000488478.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr6_-_33385902 0.32 ENST00000374500.5
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr16_-_88923285 0.32 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
 GALNS
 galactosamine (N-acetyl)-6-sulfate sulfatase
chr15_-_83316254 0.31 ENST00000567678.1
ENST00000450751.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr6_-_33385870 0.31 ENST00000488034.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr2_-_85829780 0.31 ENST00000334462.5
 TMEM150A
 transmembrane protein 150A
chr2_-_85829811 0.31 ENST00000306353.3
 TMEM150A
 transmembrane protein 150A
chr6_-_33385655 0.31 ENST00000440279.3
ENST00000607266.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr6_-_33385823 0.30 ENST00000494751.1
ENST00000374496.3
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr19_+_40854559 0.30 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
 PLD3
 phospholipase D family, member 3
chr5_-_14871866 0.29 ENST00000284268.6
 ANKH
 ANKH inorganic pyrophosphate transport regulator
chr1_-_154531095 0.29 ENST00000292211.4
 UBE2Q1
 ubiquitin-conjugating enzyme E2Q family member 1
chr5_+_172483347 0.29 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
 CREBRF
 CREB3 regulatory factor
chr17_+_39394250 0.29 ENST00000254072.6
 KRTAP9-8
 keratin associated protein 9-8
chr22_+_35695793 0.29 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
 TOM1
 target of myb1 (chicken)
chr19_-_48018203 0.29 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
chr4_+_128651530 0.28 ENST00000281154.4
 SLC25A31
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr10_+_99344071 0.28 ENST00000370647.4
ENST00000370646.4
 HOGA1
 4-hydroxy-2-oxoglutarate aldolase 1
chr14_+_96505659 0.28 ENST00000555004.1
 C14orf132
 chromosome 14 open reading frame 132
chr19_-_55691377 0.28 ENST00000589172.1
 SYT5
 synaptotagmin V
chr9_+_133320301 0.28 ENST00000352480.5
 ASS1
 argininosuccinate synthase 1
chr12_+_56109810 0.27 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
 RP11-644F5.10
BLOC1S1
 Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_84937314 0.27 ENST00000257766.4
ENST00000403245.3
 KIAA1009
 KIAA1009
chr15_-_81616446 0.27 ENST00000302824.6
 STARD5
 StAR-related lipid transfer (START) domain containing 5
chr8_-_120685608 0.26 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr22_+_31003190 0.26 ENST00000407817.3
 TCN2
 transcobalamin II
chr16_+_85061367 0.26 ENST00000538274.1
ENST00000258180.3
 KIAA0513
 KIAA0513
chr19_+_37342547 0.26 ENST00000331800.4
ENST00000586646.1
 ZNF345
 zinc finger protein 345
chr11_-_66336060 0.26 ENST00000310325.5
 CTSF
 cathepsin F
chr13_+_113951532 0.26 ENST00000332556.4
 LAMP1
 lysosomal-associated membrane protein 1
chrX_-_101397433 0.25 ENST00000372774.3
 TCEAL6
 transcription elongation factor A (SII)-like 6
chrX_+_102469997 0.25 ENST00000372695.5
ENST00000372691.3
 BEX4
 brain expressed, X-linked 4
chr17_+_42422662 0.25 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
 GRN
 granulin
chr9_-_114557207 0.24 ENST00000374287.3
ENST00000374283.5
 C9orf84
 chromosome 9 open reading frame 84
chr1_-_11866034 0.24 ENST00000376590.3
 MTHFR
 methylenetetrahydrofolate reductase (NAD(P)H)
chr8_-_120605194 0.24 ENST00000522167.1
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_+_44084503 0.24 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
 SERF2
 small EDRK-rich factor 2
chr17_+_42422637 0.24 ENST00000053867.3
ENST00000588143.1
 GRN
 granulin
chr16_-_5083589 0.24 ENST00000563578.1
ENST00000562346.2
 NAGPA
 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr12_+_56110247 0.24 ENST00000551926.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chrX_-_34675391 0.23 ENST00000275954.3
 TMEM47
 transmembrane protein 47
chr17_+_78075498 0.23 ENST00000302262.3
 GAA
 glucosidase, alpha; acid
chr12_+_133613878 0.22 ENST00000392319.2
ENST00000543758.1
 ZNF84
 zinc finger protein 84
chr5_-_121413974 0.22 ENST00000231004.4
 LOX
 lysyl oxidase
chr21_+_38445539 0.22 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
 TTC3
 tetratricopeptide repeat domain 3
chr2_+_220042933 0.22 ENST00000430297.2
 FAM134A
 family with sequence similarity 134, member A
chr16_-_5083917 0.22 ENST00000312251.3
ENST00000381955.3
 NAGPA
 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr11_-_6640585 0.22 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
 TPP1
 tripeptidyl peptidase I
chr6_-_46293378 0.22 ENST00000330430.6
 RCAN2
 regulator of calcineurin 2
chr19_-_12886327 0.22 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
 HOOK2
 hook microtubule-tethering protein 2
chr9_+_133320339 0.21 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
 ASS1
 argininosuccinate synthase 1
chr1_-_155211017 0.21 ENST00000536770.1
ENST00000368373.3
 GBA
 glucosidase, beta, acid
chr1_-_154928562 0.21 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
 PBXIP1
 pre-B-cell leukemia homeobox interacting protein 1
chr8_-_103668114 0.21 ENST00000285407.6
 KLF10
 Kruppel-like factor 10
chr19_-_45681482 0.21 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
 TRAPPC6A
 trafficking protein particle complex 6A
chr9_-_98279241 0.21 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
 PTCH1
 patched 1
chr1_-_241520525 0.21 ENST00000366565.1
 RGS7
 regulator of G-protein signaling 7
chr22_-_39636914 0.20 ENST00000381551.4
 PDGFB
 platelet-derived growth factor beta polypeptide
chr1_+_150245177 0.20 ENST00000369098.3
 C1orf54
 chromosome 1 open reading frame 54
chr12_+_56109926 0.20 ENST00000547076.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chr1_-_155211065 0.20 ENST00000427500.3
 GBA
 glucosidase, beta, acid
chr2_+_46926326 0.20 ENST00000394861.2
 SOCS5
 suppressor of cytokine signaling 5
chr8_-_13134045 0.20 ENST00000512044.2
 DLC1
 deleted in liver cancer 1
chr16_+_66914264 0.20 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
 PDP2
 pyruvate dehyrogenase phosphatase catalytic subunit 2
chr9_+_74526532 0.19 ENST00000486911.2
 C9orf85
 chromosome 9 open reading frame 85
chr10_-_50970322 0.19 ENST00000374103.4
 OGDHL
 oxoglutarate dehydrogenase-like
chr4_+_668348 0.19 ENST00000511290.1
 MYL5
 myosin, light chain 5, regulatory
chr4_+_667686 0.19 ENST00000505477.1
 MYL5
 myosin, light chain 5, regulatory
chr16_+_1401924 0.19 ENST00000204679.4
ENST00000529110.1
 GNPTG
 N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr9_+_6757634 0.19 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
 KDM4C
 lysine (K)-specific demethylase 4C
chr17_-_61951090 0.19 ENST00000345366.7
ENST00000392886.2
ENST00000336844.5
ENST00000560142.1
 CSH2
 chorionic somatomammotropin hormone 2
chrX_+_118108601 0.19 ENST00000371628.3
 LONRF3
 LON peptidase N-terminal domain and ring finger 3
chrX_+_118108571 0.19 ENST00000304778.7
 LONRF3
 LON peptidase N-terminal domain and ring finger 3
chr7_-_27196267 0.19 ENST00000242159.3
 HOXA7
 homeobox A7
chr1_+_183605200 0.19 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr16_+_8806800 0.18 ENST00000561870.1
ENST00000396600.2
 ABAT
 4-aminobutyrate aminotransferase
chr3_+_158519654 0.18 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1
 major facilitator superfamily domain containing 1
chr15_-_72668805 0.18 ENST00000268097.5
 HEXA
 hexosaminidase A (alpha polypeptide)
chr17_+_65821636 0.18 ENST00000544778.2
 BPTF
 bromodomain PHD finger transcription factor
chr6_+_41010293 0.18 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
 TSPO2
 translocator protein 2
chr9_-_138391692 0.18 ENST00000429260.2
 C9orf116
 chromosome 9 open reading frame 116
chr17_+_73975292 0.18 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
 TEN1
 TEN1 CST complex subunit
chr12_+_113796347 0.18 ENST00000545182.2
ENST00000280800.3
 PLBD2
 phospholipase B domain containing 2
chr19_-_46974664 0.18 ENST00000438932.2
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr15_-_83316087 0.18 ENST00000568757.1
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr7_-_29186008 0.18 ENST00000396276.3
ENST00000265394.5
 CPVL
 carboxypeptidase, vitellogenic-like
chr1_-_241520385 0.18 ENST00000366564.1
 RGS7
 regulator of G-protein signaling 7
chr17_+_78075361 0.18 ENST00000577106.1
ENST00000390015.3
 GAA
 glucosidase, alpha; acid
chr12_+_54332535 0.17 ENST00000243056.3
 HOXC13
 homeobox C13
chr9_-_123476719 0.17 ENST00000373930.3
 MEGF9
 multiple EGF-like-domains 9
chr2_+_46926048 0.17 ENST00000306503.5
 SOCS5
 suppressor of cytokine signaling 5
chr3_-_4508925 0.17 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
 SUMF1
 sulfatase modifying factor 1
chr16_+_4421841 0.17 ENST00000304735.3
 VASN
 vasorin
chr16_-_67514982 0.17 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr10_-_50970382 0.17 ENST00000419399.1
ENST00000432695.1
 OGDHL
 oxoglutarate dehydrogenase-like
chr9_-_123476612 0.17 ENST00000426959.1
 MEGF9
 multiple EGF-like-domains 9
chrX_+_102840408 0.17 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
 TCEAL4
 transcription elongation factor A (SII)-like 4
chr19_-_46974741 0.17 ENST00000313683.10
ENST00000602246.1
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr7_+_116593433 0.17 ENST00000323984.3
ENST00000393449.1
 ST7
 suppression of tumorigenicity 7
chr19_+_39903185 0.16 ENST00000409794.3
 PLEKHG2
 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr2_-_85829496 0.16 ENST00000409668.1
 TMEM150A
 transmembrane protein 150A
chr5_-_133706695 0.16 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
 CDKL3
 cyclin-dependent kinase-like 3
chr15_-_72668185 0.16 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
 HEXA
 hexosaminidase A (alpha polypeptide)
chr17_-_79791118 0.16 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
 FAM195B
 family with sequence similarity 195, member B
chr9_+_34652164 0.16 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr10_+_111985713 0.16 ENST00000239007.7
 MXI1
 MAX interactor 1, dimerization protein
chr12_+_6644443 0.16 ENST00000396858.1
 GAPDH
 glyceraldehyde-3-phosphate dehydrogenase
chr5_+_78532003 0.15 ENST00000396137.4
 JMY
 junction mediating and regulatory protein, p53 cofactor
chr1_+_11866270 0.15 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
 CLCN6
 chloride channel, voltage-sensitive 6
chr11_-_63376013 0.15 ENST00000540943.1
 PLA2G16
 phospholipase A2, group XVI
chr2_-_211036051 0.15 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
 KANSL1L
 KAT8 regulatory NSL complex subunit 1-like
chr9_-_21994344 0.15 ENST00000530628.2
ENST00000361570.3
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr2_+_238499812 0.15 ENST00000452801.1
 AC104667.3
 AC104667.3
chr8_+_1922024 0.15 ENST00000320248.3
 KBTBD11
 kelch repeat and BTB (POZ) domain containing 11
chr7_+_99699280 0.15 ENST00000421755.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr8_+_104383728 0.15 ENST00000330295.5
 CTHRC1
 collagen triple helix repeat containing 1
chr16_-_4292071 0.15 ENST00000399609.3
 SRL
 sarcalumenin
chr16_-_67185117 0.15 ENST00000449549.3
 B3GNT9
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr4_+_37245799 0.14 ENST00000309447.5
 KIAA1239
 KIAA1239
chrX_-_152486108 0.14 ENST00000356661.5
 MAGEA1
 melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr11_+_18344106 0.14 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
chr22_-_39637135 0.14 ENST00000440375.1
 PDGFB
 platelet-derived growth factor beta polypeptide
chr2_+_68872954 0.14 ENST00000394342.2
 PROKR1
 prokineticin receptor 1
chr16_+_84178874 0.14 ENST00000378553.5
 DNAAF1
 dynein, axonemal, assembly factor 1
chr2_-_133427767 0.14 ENST00000397463.2
 LYPD1
 LY6/PLAUR domain containing 1
chr11_-_70507901 0.14 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr3_-_197686847 0.14 ENST00000265239.6
 IQCG
 IQ motif containing G
chrX_-_100872911 0.14 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6
 armadillo repeat containing, X-linked 6
chr12_-_112450915 0.14 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
 TMEM116
 transmembrane protein 116
chr2_+_204103663 0.14 ENST00000356079.4
ENST00000429815.2
 CYP20A1
 cytochrome P450, family 20, subfamily A, polypeptide 1
chr16_-_65155833 0.14 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_-_66360548 0.14 ENST00000333861.3
 CCDC87
 coiled-coil domain containing 87
chr2_-_175870085 0.14 ENST00000409156.3
 CHN1
 chimerin 1
chr7_-_150675372 0.14 ENST00000262186.5
 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_+_156712372 0.13 ENST00000541131.1
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr10_-_93392811 0.13 ENST00000238994.5
 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
chr7_+_116593568 0.13 ENST00000446490.1
 ST7
 suppression of tumorigenicity 7
chr17_-_46688334 0.13 ENST00000239165.7
 HOXB7
 homeobox B7
chr5_+_133706865 0.13 ENST00000265339.2
 UBE2B
 ubiquitin-conjugating enzyme E2B
chr8_+_136469684 0.13 ENST00000355849.5
 KHDRBS3
 KH domain containing, RNA binding, signal transduction associated 3
chr5_-_139944196 0.13 ENST00000357560.4
 APBB3
 amyloid beta (A4) precursor protein-binding, family B, member 3
chr19_-_45004556 0.13 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
 ZNF180
 zinc finger protein 180
chr16_+_85645007 0.13 ENST00000405402.2
 GSE1
 Gse1 coiled-coil protein
chr1_-_205290865 0.13 ENST00000367157.3
 NUAK2
 NUAK family, SNF1-like kinase, 2
chr1_-_101360331 0.13 ENST00000416479.1
ENST00000370113.3
 EXTL2
 exostosin-like glycosyltransferase 2
chr2_-_190044480 0.13 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr1_-_198509804 0.13 ENST00000489986.1
ENST00000367382.1
 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr17_-_34524157 0.13 ENST00000378354.4
ENST00000394484.1
 CCL3L3
 chemokine (C-C motif) ligand 3-like 3
chr17_+_34087888 0.13 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
 C17orf50
 chromosome 17 open reading frame 50
chr9_-_16870704 0.13 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
 BNC2
 basonuclin 2
chr3_+_38323785 0.13 ENST00000466887.1
ENST00000448498.1
 SLC22A14
 solute carrier family 22, member 14
chr7_+_101917407 0.13 ENST00000487284.1
 CUX1
 cut-like homeobox 1
chr9_-_21994597 0.13 ENST00000579755.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr16_+_2097970 0.13 ENST00000382538.6
ENST00000401874.2
ENST00000353929.4
 TSC2
 tuberous sclerosis 2
chr17_-_39093672 0.13 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23
 keratin 23 (histone deacetylase inducible)
chr17_+_3539744 0.13 ENST00000046640.3
ENST00000381870.3
 CTNS
 cystinosin, lysosomal cystine transporter
chr12_-_90102594 0.13 ENST00000428670.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr5_-_35195338 0.13 ENST00000509839.1
 PRLR
 prolactin receptor
chrX_+_102883887 0.13 ENST00000372625.3
ENST00000372624.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chrX_+_77166172 0.13 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr7_+_4815238 0.13 ENST00000348624.4
ENST00000401897.1
 AP5Z1
 adaptor-related protein complex 5, zeta 1 subunit
chr5_-_176730676 0.13 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
 RAB24
 RAB24, member RAS oncogene family
chr16_+_2098003 0.12 ENST00000439673.2
ENST00000350773.4
 TSC2
 tuberous sclerosis 2
chr22_-_36903069 0.12 ENST00000216187.6
ENST00000423980.1
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr17_-_35969409 0.12 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
 SYNRG
 synergin, gamma
chr17_+_1627834 0.12 ENST00000419248.1
ENST00000418841.1
 WDR81
 WD repeat domain 81
chr6_-_160679905 0.12 ENST00000366953.3
 SLC22A2
 solute carrier family 22 (organic cation transporter), member 2
chr4_-_186733363 0.12 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.4 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 1.0 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.3 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.3 GO:1900241 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.7 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.2 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.8 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.8 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0060139 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:0043132 NAD transport(GO:0043132)
0.0 0.1 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0090650 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.0 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.0 GO:0061054 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986)
0.0 0.0 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0031016 pancreas development(GO:0031016)
0.0 0.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.0 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.3 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 4.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838) new growing cell tip(GO:0035841)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0031252 cell leading edge(GO:0031252)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.5 GO:0044432 endoplasmic reticulum lumen(GO:0005788) endoplasmic reticulum part(GO:0044432)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.7 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.8 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.0 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.0 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism