Project

Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

Navigation
Downloads

Results for SRF

Z-value: 2.02

Motif logo

Transcription factors associated with SRF

Gene Symbol Gene ID Gene Info
ENSG00000112658.6 SRF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRFhg19_v2_chr6_+_43139037_43139094-0.235.9e-01Click!

Activity profile of SRF motif

Sorted Z-values of SRF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SRF

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr20_+_35169885 4.51 ENST00000279022.2
ENST00000346786.2
MYL9
myosin, light chain 9, regulatory
chr8_+_97597148 3.22 ENST00000521590.1
SDC2
syndecan 2
chr5_+_92919043 2.89 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr10_-_64576105 2.67 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr10_+_31610064 1.99 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr19_+_2476116 1.64 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr5_+_40679584 1.48 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr9_-_79520989 1.46 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr5_-_111093167 1.44 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr9_+_36136700 1.40 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLIPR2
GLI pathogenesis-related 2
chr16_-_3350614 1.35 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr5_+_137801160 1.33 ENST00000239938.4
EGR1
early growth response 1
chr9_+_92219919 1.17 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr14_+_74034310 1.16 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr1_-_86043921 1.11 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_-_124080203 0.93 ENST00000504926.1
ZNF608
zinc finger protein 608
chr11_+_117070037 0.90 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr2_-_106054952 0.85 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chrX_+_22056165 0.83 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr5_+_137774706 0.79 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr3_+_49027308 0.76 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr11_-_65626753 0.74 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr2_-_106015491 0.72 ENST00000408995.1
ENST00000393353.3
ENST00000322142.8
FHL2
four and a half LIM domains 2
chr12_+_59989791 0.71 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr9_+_124088860 0.71 ENST00000373806.1
GSN
gelsolin
chr4_+_87928413 0.71 ENST00000544085.1
AFF1
AF4/FMR2 family, member 1
chr12_+_59989918 0.70 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr6_+_151561085 0.70 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_106015527 0.69 ENST00000344213.4
ENST00000358129.4
FHL2
four and a half LIM domains 2
chr7_-_27183263 0.68 ENST00000222726.3
HOXA5
homeobox A5
chr5_-_176923803 0.64 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr10_-_90712520 0.64 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_-_46904946 0.62 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr5_-_176923846 0.62 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr3_-_46904918 0.62 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_+_187930719 0.57 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_+_83776324 0.56 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr2_-_128432639 0.56 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2
LIM and senescent cell antigen-like domains 2
chr6_-_111804905 0.50 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr22_-_36357671 0.49 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_74120094 0.48 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr3_-_99594948 0.48 ENST00000471562.1
ENST00000495625.2
FILIP1L
filamin A interacting protein 1-like
chr2_+_56179262 0.48 ENST00000606639.1
RP11-481J13.1
RP11-481J13.1
chr1_-_89531041 0.47 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr6_+_151561506 0.45 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr15_-_35088340 0.45 ENST00000290378.4
ACTC1
actin, alpha, cardiac muscle 1
chr11_-_65626797 0.43 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr11_-_57282349 0.42 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr2_-_172087824 0.42 ENST00000521943.1
TLK1
tousled-like kinase 1
chr12_+_75874460 0.39 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr15_+_74218787 0.37 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr3_-_99595037 0.36 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr17_-_72358001 0.36 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr19_+_16178317 0.34 ENST00000344824.6
ENST00000538887.1
TPM4
tropomyosin 4
chr7_+_143078652 0.34 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr15_-_55581954 0.32 ENST00000336787.1
RAB27A
RAB27A, member RAS oncogene family
chr12_-_6772303 0.31 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr12_+_75874580 0.31 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr1_+_223889285 0.31 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr5_-_58295712 0.31 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_208084729 0.30 ENST00000310833.7
ENST00000356522.4
CD34
CD34 molecule
chr1_-_89591749 0.30 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr19_+_13135386 0.29 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_121379739 0.29 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_91487770 0.28 ENST00000337393.5
ZNF644
zinc finger protein 644
chr15_+_96873921 0.27 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_-_4890649 0.26 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr19_-_36247910 0.25 ENST00000587965.1
ENST00000004982.3
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr17_-_79481666 0.25 ENST00000575659.1
ACTG1
actin, gamma 1
chr10_-_17659234 0.24 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr6_-_159466042 0.24 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr11_-_2162468 0.23 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_219283815 0.23 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1
villin 1
chr18_-_3219847 0.23 ENST00000261606.7
MYOM1
myomesin 1
chr3_-_71294304 0.23 ENST00000498215.1
FOXP1
forkhead box P1
chr11_-_2162162 0.22 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_+_28099683 0.21 ENST00000373943.4
STX12
syntaxin 12
chr11_+_59807748 0.21 ENST00000278855.2
ENST00000532905.1
PLAC1L
oocyte secreted protein 2
chr1_+_223889310 0.20 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr1_+_50574585 0.20 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr3_-_157221380 0.20 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr10_+_88428206 0.19 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr3_+_9834758 0.19 ENST00000485273.1
ENST00000433034.1
ENST00000397256.1
ARPC4
ARPC4-TTLL3
actin related protein 2/3 complex, subunit 4, 20kDa
ARPC4-TTLL3 readthrough
chr19_+_35861831 0.19 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr3_-_157221357 0.19 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr10_-_16859361 0.18 ENST00000377921.3
RSU1
Ras suppressor protein 1
chr20_-_21494654 0.18 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr4_+_87928140 0.18 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr9_-_35691017 0.18 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr9_-_98269481 0.17 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr10_-_16859442 0.17 ENST00000602389.1
ENST00000345264.5
RSU1
Ras suppressor protein 1
chr1_+_219347186 0.17 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr9_-_98269699 0.17 ENST00000429896.2
PTCH1
patched 1
chr10_+_88428370 0.17 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chrX_-_153602991 0.17 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr19_-_35166604 0.17 ENST00000601241.1
SCGB2B2
secretoglobin, family 2B, member 2
chr2_+_87769459 0.16 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_-_9834375 0.16 ENST00000343450.2
ENST00000301964.2
TADA3
transcriptional adaptor 3
chr1_-_229569834 0.16 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr10_-_17659357 0.16 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr1_-_152332480 0.16 ENST00000388718.5
FLG2
filaggrin family member 2
chr1_+_6105974 0.16 ENST00000378083.3
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr16_+_30077055 0.16 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr1_+_219347203 0.15 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr17_-_41132010 0.15 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1
PTGES3L-AARSD1 readthrough
chr16_+_30077098 0.15 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr3_+_9834179 0.14 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr19_+_57901208 0.13 ENST00000366197.5
ENST00000596282.1
ENST00000597400.1
ENST00000598895.1
ENST00000336128.7
ENST00000596617.1
ZNF548
AC003002.6
zinc finger protein 548
Uncharacterized protein
chr16_+_30383613 0.13 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr17_+_3379284 0.13 ENST00000263080.2
ASPA
aspartoacylase
chr2_-_73520667 0.12 ENST00000545030.1
ENST00000436467.2
EGR4
early growth response 4
chr4_-_10118469 0.12 ENST00000499869.2
WDR1
WD repeat domain 1
chr10_-_29923893 0.12 ENST00000355867.4
SVIL
supervillin
chr3_+_63953415 0.12 ENST00000484332.1
ATXN7
ataxin 7
chr10_+_96162242 0.12 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr2_-_112237835 0.11 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr8_-_101321584 0.11 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr17_+_33474826 0.10 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr17_-_4871085 0.10 ENST00000575142.1
ENST00000206020.3
SPAG7
sperm associated antigen 7
chr17_+_33474860 0.10 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr4_-_109087872 0.10 ENST00000510624.1
LEF1
lymphoid enhancer-binding factor 1
chr6_+_158402860 0.10 ENST00000367122.2
ENST00000367121.3
ENST00000355585.4
ENST00000367113.4
SYNJ2
synaptojanin 2
chr11_-_71823796 0.10 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr4_-_10118573 0.10 ENST00000382452.2
ENST00000382451.2
WDR1
WD repeat domain 1
chr3_-_185641681 0.09 ENST00000259043.7
TRA2B
transformer 2 beta homolog (Drosophila)
chr2_+_139259324 0.09 ENST00000280098.4
SPOPL
speckle-type POZ protein-like
chr2_-_209118974 0.08 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr2_-_31030277 0.07 ENST00000534090.2
ENST00000295055.8
CAPN13
calpain 13
chr2_-_161264385 0.06 ENST00000409972.1
RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_4890919 0.06 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chr7_+_88388628 0.06 ENST00000333190.4
ZNF804B
zinc finger protein 804B
chr14_-_94443105 0.05 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr19_+_45971246 0.05 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr11_-_71823715 0.05 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr17_-_55911970 0.05 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr3_+_9834227 0.05 ENST00000287613.7
ENST00000397261.3
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr11_-_47374246 0.04 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr12_-_125398850 0.03 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC
ubiquitin C
chrX_-_103499602 0.03 ENST00000372588.4
ESX1
ESX homeobox 1
chr1_+_11994715 0.03 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr11_-_71823266 0.03 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr18_+_54318566 0.03 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr1_-_23340400 0.02 ENST00000440767.2
C1orf234
chromosome 1 open reading frame 234
chr4_+_186064395 0.02 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr7_+_114055052 0.02 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr18_-_3220106 0.02 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr7_-_94285402 0.02 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr7_+_107531580 0.01 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD
dihydrolipoamide dehydrogenase
chr4_-_54930790 0.01 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr11_+_34073195 0.01 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr5_-_169816638 0.00 ENST00000521859.1
ENST00000274629.4
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr11_+_17281900 0.00 ENST00000530527.1
NUCB2
nucleobindin 2
chr7_-_5570229 0.00 ENST00000331789.5
ACTB
actin, beta
chr2_+_191792376 0.00 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0035284 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 3.2 GO:0008218 bioluminescence(GO:0008218)
0.5 1.5 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.5 2.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.4 1.3 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.3 1.7 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.7 GO:0060435 bronchiole development(GO:0060435)
0.2 2.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 1.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 1.2 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 0.8 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 0.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 0.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.7 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 2.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 1.1 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.4 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 4.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 0.2 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 1.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 1.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.8 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 2.9 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 5.1 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0032982 myosin filament(GO:0032982)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.1 2.6 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 3.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 1.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 5.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 1.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 1.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 2.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 2.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0043199 sulfate binding(GO:0043199)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 3.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)