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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for STAT1_STAT3_BCL6

Z-value: 1.76

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
STAT1
ENSG00000115415.14 STAT1
STAT3
ENSG00000168610.10 STAT3
BCL6
ENSG00000113916.13 BCL6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL6hg19_v2_chr3_-_187454281_1874543570.831.0e-02Click!
STAT1hg19_v2_chr2_-_191878874_1918789760.762.9e-02Click!
STAT3hg19_v2_chr17_-_40540586_405406000.667.7e-02Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_30396948 2.99 ENST00000331968.5
 PRKD1
 protein kinase D1
chr8_-_120651020 2.90 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_+_163038565 2.81 ENST00000421743.2
 RGS4
 regulator of G-protein signaling 4
chr12_+_53443963 2.76 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr12_-_91539918 2.46 ENST00000548218.1
 DCN
 decorin
chr12_+_53443680 2.45 ENST00000314250.6
ENST00000451358.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_163039143 2.42 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
 RGS4
 regulator of G-protein signaling 4
chr3_-_93692781 2.22 ENST00000394236.3
 PROS1
 protein S (alpha)
chr5_-_111092873 2.14 ENST00000509025.1
ENST00000515855.1
 NREP
 neuronal regeneration related protein
chr2_-_190044480 2.06 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr8_-_27469196 1.92 ENST00000546343.1
ENST00000560566.1
 CLU
 clusterin
chr6_+_108977520 1.86 ENST00000540898.1
 FOXO3
 forkhead box O3
chr3_+_45067659 1.81 ENST00000296130.4
 CLEC3B
 C-type lectin domain family 3, member B
chr9_-_89562104 1.80 ENST00000298743.7
 GAS1
 growth arrest-specific 1
chr1_-_144994909 1.61 ENST00000369347.4
ENST00000369354.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr14_-_92414055 1.53 ENST00000342058.4
 FBLN5
 fibulin 5
chr1_+_221051699 1.44 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr5_-_146781153 1.39 ENST00000520473.1
 DPYSL3
 dihydropyrimidinase-like 3
chr5_-_111093081 1.32 ENST00000453526.2
ENST00000509427.1
 NREP
 neuronal regeneration related protein
chr8_-_27468945 1.31 ENST00000405140.3
 CLU
 clusterin
chr22_-_31503490 1.26 ENST00000400299.2
 SELM
 Selenoprotein M
chr5_-_111093340 1.24 ENST00000508870.1
 NREP
 neuronal regeneration related protein
chr5_-_111093167 1.14 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr8_-_27468842 1.14 ENST00000523500.1
 CLU
 clusterin
chr19_-_58864848 1.11 ENST00000263100.3
 A1BG
 alpha-1-B glycoprotein
chr5_-_111093406 1.10 ENST00000379671.3
 NREP
 neuronal regeneration related protein
chr5_-_111092930 1.09 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr6_+_84222220 1.08 ENST00000369700.3
 PRSS35
 protease, serine, 35
chrX_-_48931648 1.01 ENST00000376386.3
ENST00000376390.4
 PRAF2
 PRA1 domain family, member 2
chr2_-_128399706 0.99 ENST00000426981.1
 LIMS2
 LIM and senescent cell antigen-like domains 2
chr8_-_120685608 0.98 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr19_-_45927622 0.97 ENST00000300853.3
ENST00000589165.1
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr22_-_50699701 0.97 ENST00000395780.1
 MAPK12
 mitogen-activated protein kinase 12
chr2_-_175499294 0.93 ENST00000392547.2
 WIPF1
 WAS/WASL interacting protein family, member 1
chr19_+_10197463 0.90 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr10_-_90751038 0.90 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr1_-_144995074 0.88 ENST00000534536.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr4_+_126237554 0.86 ENST00000394329.3
 FAT4
 FAT atypical cadherin 4
chr3_-_187455680 0.83 ENST00000438077.1
 BCL6
 B-cell CLL/lymphoma 6
chr10_-_33625154 0.82 ENST00000265371.4
 NRP1
 neuropilin 1
chr17_-_76356148 0.82 ENST00000587578.1
ENST00000330871.2
 SOCS3
 suppressor of cytokine signaling 3
chr4_-_175443943 0.82 ENST00000296522.6
 HPGD
 hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_-_31845914 0.81 ENST00000373713.2
 FABP3
 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr9_-_139891165 0.75 ENST00000494426.1
 CLIC3
 chloride intracellular channel 3
chr7_-_74267836 0.74 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
 GTF2IRD2
 GTF2I repeat domain containing 2
chr19_-_40324255 0.74 ENST00000593685.1
ENST00000600611.1
 DYRK1B
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr1_+_213123915 0.73 ENST00000366968.4
ENST00000490792.1
 VASH2
 vasohibin 2
chr5_+_145718587 0.73 ENST00000230732.4
 POU4F3
 POU class 4 homeobox 3
chr1_-_144994840 0.71 ENST00000369351.3
ENST00000369349.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr1_+_154300217 0.70 ENST00000368489.3
 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr3_+_183894566 0.69 ENST00000439647.1
 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
chr14_-_106406090 0.68 ENST00000390593.2
 IGHV6-1
 immunoglobulin heavy variable 6-1
chr1_-_144995002 0.67 ENST00000369356.4
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr2_+_87754887 0.67 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
 LINC00152
 long intergenic non-protein coding RNA 152
chr2_+_87755054 0.67 ENST00000423846.1
 LINC00152
 long intergenic non-protein coding RNA 152
chr2_+_87754989 0.66 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
 LINC00152
 long intergenic non-protein coding RNA 152
chr19_+_35225060 0.65 ENST00000599244.1
ENST00000392232.3
 ZNF181
 zinc finger protein 181
chr10_+_95848824 0.65 ENST00000371385.3
ENST00000371375.1
 PLCE1
 phospholipase C, epsilon 1
chr17_+_6347761 0.65 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
 FAM64A
 family with sequence similarity 64, member A
chr1_+_202431859 0.65 ENST00000391959.3
ENST00000367270.4
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr7_+_74508372 0.64 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
 GTF2IRD2B
 GTF2I repeat domain containing 2B
chr8_+_104384616 0.64 ENST00000520337.1
 CTHRC1
 collagen triple helix repeat containing 1
chr19_+_15218180 0.63 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
 SYDE1
 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_+_6347729 0.62 ENST00000572447.1
 FAM64A
 family with sequence similarity 64, member A
chr8_+_38586068 0.60 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr2_-_167232484 0.59 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
 SCN9A
 sodium channel, voltage-gated, type IX, alpha subunit
chr6_+_32821924 0.58 ENST00000374859.2
ENST00000453265.2
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr3_-_112329110 0.58 ENST00000479368.1
 CCDC80
 coiled-coil domain containing 80
chr11_+_5710919 0.55 ENST00000379965.3
ENST00000425490.1
 TRIM22
 tripartite motif containing 22
chr5_+_148521381 0.55 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr16_+_30996502 0.54 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
 HSD3B7
 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_-_112356944 0.53 ENST00000461431.1
 CCDC80
 coiled-coil domain containing 80
chr19_-_51875894 0.53 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
 NKG7
 natural killer cell group 7 sequence
chrX_+_103031421 0.52 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
 PLP1
 proteolipid protein 1
chr1_-_68299130 0.51 ENST00000370982.3
 GNG12
 guanine nucleotide binding protein (G protein), gamma 12
chr5_+_140625147 0.50 ENST00000231173.3
 PCDHB15
 protocadherin beta 15
chr19_+_35168567 0.50 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
 ZNF302
 zinc finger protein 302
chrX_-_70473957 0.49 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
 ZMYM3
 zinc finger, MYM-type 3
chr19_+_2476116 0.49 ENST00000215631.4
ENST00000587345.1
 GADD45B
 growth arrest and DNA-damage-inducible, beta
chr17_-_76274572 0.48 ENST00000374945.1
 RP11-219G17.4
 RP11-219G17.4
chr19_-_44405941 0.48 ENST00000587128.1
 RP11-15A1.3
 RP11-15A1.3
chr19_+_35168633 0.48 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr1_+_153631130 0.47 ENST00000368685.5
 SNAPIN
 SNAP-associated protein
chr3_+_185000729 0.47 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
chr19_-_40324767 0.46 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
 DYRK1B
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr16_-_67260691 0.46 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
 LRRC29
 leucine rich repeat containing 29
chr15_+_63340775 0.46 ENST00000559281.1
ENST00000317516.7
 TPM1
 tropomyosin 1 (alpha)
chr2_-_224467093 0.46 ENST00000305409.2
 SCG2
 secretogranin II
chr7_+_134464376 0.45 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr3_+_45927994 0.45 ENST00000357632.2
ENST00000395963.2
 CCR9
 chemokine (C-C motif) receptor 9
chr19_+_10196981 0.44 ENST00000591813.1
 C19orf66
 chromosome 19 open reading frame 66
chr7_-_38670957 0.44 ENST00000325590.5
ENST00000428293.2
 AMPH
 amphiphysin
chr19_+_55281260 0.44 ENST00000336077.6
ENST00000291633.7
 KIR2DL1
 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr9_-_123239632 0.43 ENST00000416449.1
 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
chr7_-_38671098 0.43 ENST00000356264.2
 AMPH
 amphiphysin
chr17_+_36858694 0.43 ENST00000563897.1
 CTB-58E17.1
 CTB-58E17.1
chr10_+_35484793 0.42 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
 CREM
 cAMP responsive element modulator
chr3_-_42744312 0.42 ENST00000416756.1
ENST00000441594.1
 HHATL
 hedgehog acyltransferase-like
chr16_+_53133070 0.42 ENST00000565832.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr5_-_177423243 0.42 ENST00000308304.2
 PROP1
 PROP paired-like homeobox 1
chr4_-_140005443 0.42 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
 ELF2
 E74-like factor 2 (ets domain transcription factor)
chr19_+_35168547 0.42 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
 ZNF302
 zinc finger protein 302
chr19_-_44809121 0.41 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
 ZNF235
 zinc finger protein 235
chr19_-_44405623 0.40 ENST00000591815.1
 RP11-15A1.3
 RP11-15A1.3
chr21_+_26934165 0.40 ENST00000456917.1
 MIR155HG
 MIR155 host gene (non-protein coding)
chr9_-_123812542 0.40 ENST00000223642.1
 C5
 complement component 5
chr4_-_159094194 0.40 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
 FAM198B
 family with sequence similarity 198, member B
chr5_+_172483347 0.40 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
 CREBRF
 CREB3 regulatory factor
chr1_+_155146318 0.40 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
 TRIM46
 tripartite motif containing 46
chr4_-_140005341 0.40 ENST00000379549.2
ENST00000512627.1
 ELF2
 E74-like factor 2 (ets domain transcription factor)
chr11_-_111782484 0.38 ENST00000533971.1
 CRYAB
 crystallin, alpha B
chr12_+_21679220 0.38 ENST00000256969.2
 C12orf39
 chromosome 12 open reading frame 39
chr6_-_52859046 0.38 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
 GSTA4
 glutathione S-transferase alpha 4
chr1_+_59775752 0.37 ENST00000371212.1
 FGGY
 FGGY carbohydrate kinase domain containing
chr15_+_63340734 0.37 ENST00000560959.1
 TPM1
 tropomyosin 1 (alpha)
chr6_-_56707943 0.37 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
 DST
 dystonin
chr7_-_130353553 0.37 ENST00000330992.7
ENST00000445977.2
 COPG2
 coatomer protein complex, subunit gamma 2
chr17_+_2699697 0.36 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
 RAP1GAP2
 RAP1 GTPase activating protein 2
chr11_-_111782696 0.36 ENST00000227251.3
ENST00000526180.1
 CRYAB
 crystallin, alpha B
chr1_+_65775204 0.36 ENST00000371069.4
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr19_+_44081344 0.35 ENST00000599207.1
 PINLYP
 phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr18_+_6729698 0.35 ENST00000383472.4
 ARHGAP28
 Rho GTPase activating protein 28
chr5_-_121413974 0.35 ENST00000231004.4
 LOX
 lysyl oxidase
chr3_-_114866084 0.35 ENST00000357258.3
 ZBTB20
 zinc finger and BTB domain containing 20
chr14_+_76452090 0.35 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
 IFT43
 intraflagellar transport 43 homolog (Chlamydomonas)
chr1_+_162602244 0.35 ENST00000367922.3
ENST00000367921.3
 DDR2
 discoidin domain receptor tyrosine kinase 2
chr12_-_88974236 0.35 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
 KITLG
 KIT ligand
chrX_-_139866723 0.34 ENST00000370532.2
 CDR1
 cerebellar degeneration-related protein 1, 34kDa
chr17_+_32582293 0.34 ENST00000580907.1
ENST00000225831.4
 CCL2
 chemokine (C-C motif) ligand 2
chr12_-_7261772 0.33 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
 C1RL
 complement component 1, r subcomponent-like
chr15_-_93616892 0.33 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
 RGMA
 repulsive guidance molecule family member a
chr2_-_175547571 0.33 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
 WIPF1
 WAS/WASL interacting protein family, member 1
chr7_+_134464414 0.33 ENST00000361901.2
 CALD1
 caldesmon 1
chr15_-_60690163 0.33 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
 ANXA2
 annexin A2
chr11_+_61197572 0.32 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
 SDHAF2
 succinate dehydrogenase complex assembly factor 2
chr5_+_140723601 0.32 ENST00000253812.6
 PCDHGA3
 protocadherin gamma subfamily A, 3
chr2_-_28113217 0.32 ENST00000444339.2
 RBKS
 ribokinase
chr17_+_32683456 0.32 ENST00000225844.2
 CCL13
 chemokine (C-C motif) ligand 13
chrX_+_106045891 0.31 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
chr10_-_25010795 0.31 ENST00000416305.1
ENST00000376410.2
 ARHGAP21
 Rho GTPase activating protein 21
chr1_+_6845578 0.31 ENST00000467404.2
ENST00000439411.2
 CAMTA1
 calmodulin binding transcription activator 1
chr7_-_87936195 0.31 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
 STEAP4
 STEAP family member 4
chr2_-_106013400 0.31 ENST00000409807.1
 FHL2
 four and a half LIM domains 2
chr17_-_1619535 0.31 ENST00000573075.1
ENST00000574306.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chr16_+_70332956 0.31 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
 DDX19B
RP11-529K1.3
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr19_+_49977466 0.31 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
 FLT3LG
 fms-related tyrosine kinase 3 ligand
chr8_+_71485681 0.30 ENST00000391684.1
 AC120194.1
 AC120194.1
chr17_-_1619491 0.30 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chr5_-_132113083 0.29 ENST00000296873.7
 SEPT8
 septin 8
chr14_-_24977457 0.29 ENST00000250378.3
ENST00000206446.4
 CMA1
 chymase 1, mast cell
chr1_+_6845497 0.27 ENST00000473578.1
ENST00000557126.1
 CAMTA1
 calmodulin binding transcription activator 1
chr14_-_24806588 0.27 ENST00000555591.1
ENST00000554569.1
 RP11-934B9.3
RIPK3
 Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr21_-_31744557 0.27 ENST00000399889.2
 KRTAP13-2
 keratin associated protein 13-2
chr19_+_49977818 0.27 ENST00000594009.1
ENST00000595510.1
 FLT3LG
 fms-related tyrosine kinase 3 ligand
chr19_+_44764031 0.27 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
 ZNF233
 zinc finger protein 233
chr15_+_63340647 0.27 ENST00000404484.4
 TPM1
 tropomyosin 1 (alpha)
chr16_-_8955570 0.27 ENST00000567554.1
 CARHSP1
 calcium regulated heat stable protein 1, 24kDa
chr3_+_185046676 0.27 ENST00000428617.1
ENST00000443863.1
 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
chr16_-_8955601 0.26 ENST00000569398.1
ENST00000568968.1
 CARHSP1
 calcium regulated heat stable protein 1, 24kDa
chr19_+_39786962 0.26 ENST00000333625.2
 IFNL1
 interferon, lambda 1
chr10_+_104535994 0.26 ENST00000369889.4
 WBP1L
 WW domain binding protein 1-like
chr7_-_138386097 0.26 ENST00000421622.1
 SVOPL
 SVOP-like
chr1_-_201476274 0.26 ENST00000340006.2
 CSRP1
 cysteine and glycine-rich protein 1
chr1_+_197881592 0.26 ENST00000367391.1
ENST00000367390.3
 LHX9
 LIM homeobox 9
chr12_-_42877726 0.25 ENST00000548696.1
 PRICKLE1
 prickle homolog 1 (Drosophila)
chr14_+_22458631 0.25 ENST00000390444.1
 TRAV16
 T cell receptor alpha variable 16
chr7_-_38398721 0.25 ENST00000390346.2
 TRGV3
 T cell receptor gamma variable 3
chr11_-_65793948 0.25 ENST00000312106.5
 CATSPER1
 cation channel, sperm associated 1
chr1_-_157670528 0.25 ENST00000368186.5
ENST00000496769.1
 FCRL3
 Fc receptor-like 3
chr6_+_35995488 0.25 ENST00000229795.3
 MAPK14
 mitogen-activated protein kinase 14
chr1_-_150780757 0.25 ENST00000271651.3
 CTSK
 cathepsin K
chr19_+_44669280 0.25 ENST00000590089.1
ENST00000454662.2
 ZNF226
 zinc finger protein 226
chr12_-_56120838 0.25 ENST00000548160.1
 CD63
 CD63 molecule
chr4_+_166300084 0.25 ENST00000402744.4
 CPE
 carboxypeptidase E
chr6_-_105307711 0.25 ENST00000519645.1
ENST00000262903.4
ENST00000369125.2
 HACE1
 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr14_-_20881579 0.25 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
 TEP1
 telomerase-associated protein 1
chr16_+_29973351 0.25 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
 TMEM219
 transmembrane protein 219
chr6_+_151561085 0.25 ENST00000402676.2
 AKAP12
 A kinase (PRKA) anchor protein 12
chr9_+_18474204 0.25 ENST00000276935.6
 ADAMTSL1
 ADAMTS-like 1
chr6_+_35995531 0.24 ENST00000229794.4
 MAPK14
 mitogen-activated protein kinase 14
chr16_-_89785777 0.24 ENST00000561976.1
 VPS9D1
 VPS9 domain containing 1
chr16_-_66952779 0.24 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
 CDH16
 cadherin 16, KSP-cadherin
chr5_-_132113036 0.24 ENST00000378706.1
 SEPT8
 septin 8
chr11_-_9781068 0.24 ENST00000500698.1
 RP11-540A21.2
 RP11-540A21.2
chr5_-_132112921 0.23 ENST00000378721.4
ENST00000378701.1
 SEPT8
 septin 8
chr5_+_118691706 0.23 ENST00000415806.2
 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
chr10_-_102089729 0.23 ENST00000465680.2
 PKD2L1
 polycystic kidney disease 2-like 1
chr16_-_66952742 0.23 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
 CDH16
 cadherin 16, KSP-cadherin
chr2_+_28113583 0.23 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
 BRE
 brain and reproductive organ-expressed (TNFRSF1A modulator)
chr14_+_88471468 0.23 ENST00000267549.3
 GPR65
 G protein-coupled receptor 65
chr2_-_224702257 0.23 ENST00000409375.1
 AP1S3
 adaptor-related protein complex 1, sigma 3 subunit
chr1_-_241803679 0.23 ENST00000331838.5
 OPN3
 opsin 3
chr6_+_35995552 0.22 ENST00000468133.1
 MAPK14
 mitogen-activated protein kinase 14
chr19_+_56905024 0.22 ENST00000591172.1
ENST00000589888.1
ENST00000587979.1
ENST00000585659.1
ENST00000593109.1
 ZNF582-AS1
 ZNF582 antisense RNA 1 (head to head)
chr14_+_65381079 0.22 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
 CHURC1
FNTB
CHURC1-FNTB
 churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr8_+_28196157 0.22 ENST00000522209.1
 PNOC
 prepronociceptin
chr17_+_77021702 0.22 ENST00000392445.2
ENST00000354124.3
 C1QTNF1
 C1q and tumor necrosis factor related protein 1
chr17_-_19265982 0.22 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
 B9D1
 B9 protein domain 1
chr3_-_160117301 0.22 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
 IFT80
 intraflagellar transport 80 homolog (Chlamydomonas)
chr14_-_25519095 0.22 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
 STXBP6
 syntaxin binding protein 6 (amisyn)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 2.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.9 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.4 3.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 2.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 0.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 1.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 3.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.9 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 0.6 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.5 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.2 0.5 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 0.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.2 0.2 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.2 0.8 GO:1902336 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 2.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.9 GO:0072683 T cell extravasation(GO:0072683)
0.2 0.9 GO:0090131 mesenchyme migration(GO:0090131)
0.1 1.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.4 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 1.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.2 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.1 1.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 5.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.7 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.3 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:0006756 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 1.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.4 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.5 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.6 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.3 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.1 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:2000308 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.5 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.8 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.8 GO:0001652 granular component(GO:0001652)
0.3 4.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.2 2.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 1.5 GO:0071953 elastic fiber(GO:0071953)
0.2 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.8 GO:0005883 neurofilament(GO:0005883)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 3.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.1 0.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 1.1 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 1.4 GO:0005884 actin filament(GO:0005884)
0.0 0.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 0.8 GO:0070538 oleic acid binding(GO:0070538)
0.2 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 4.4 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 1.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 5.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 2.0 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.6 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 1.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 2.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 4.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 3.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis