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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for TBX5

Z-value: 0.82

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Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
TBX5
ENSG00000089225.15 TBX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX5hg19_v2_chr12_-_114841703_1148417260.502.1e-01Click!

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_117947724 1.26 ENST00000534111.1
 TMPRSS4
 transmembrane protease, serine 4
chr11_+_117947782 1.15 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
 TMPRSS4
 transmembrane protease, serine 4
chr12_-_52887034 0.87 ENST00000330722.6
 KRT6A
 keratin 6A
chr1_+_101702417 0.68 ENST00000305352.6
 S1PR1
 sphingosine-1-phosphate receptor 1
chr22_-_20231207 0.67 ENST00000425986.1
 RTN4R
 reticulon 4 receptor
chr6_+_150464155 0.67 ENST00000361131.4
 PPP1R14C
 protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr16_-_31147020 0.59 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
 PRSS8
 protease, serine, 8
chr1_-_205290865 0.57 ENST00000367157.3
 NUAK2
 NUAK family, SNF1-like kinase, 2
chr3_-_133748913 0.56 ENST00000310926.4
 SLCO2A1
 solute carrier organic anion transporter family, member 2A1
chr2_+_68961934 0.53 ENST00000409202.3
 ARHGAP25
 Rho GTPase activating protein 25
chr12_+_107712173 0.53 ENST00000280758.5
ENST00000420571.2
 BTBD11
 BTB (POZ) domain containing 11
chr2_+_68961905 0.53 ENST00000295381.3
 ARHGAP25
 Rho GTPase activating protein 25
chr8_+_120220561 0.50 ENST00000276681.6
 MAL2
 mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_-_216003127 0.48 ENST00000412081.1
ENST00000272895.7
 ABCA12
 ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_12677714 0.47 ENST00000376223.2
 DHRS3
 dehydrogenase/reductase (SDR family) member 3
chr18_+_33877654 0.47 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
 FHOD3
 formin homology 2 domain containing 3
chr18_-_52969844 0.47 ENST00000561831.3
 TCF4
 transcription factor 4
chr20_+_58630972 0.44 ENST00000313426.1
 C20orf197
 chromosome 20 open reading frame 197
chr14_+_75746781 0.44 ENST00000555347.1
 FOS
 FBJ murine osteosarcoma viral oncogene homolog
chr1_+_1981890 0.44 ENST00000378567.3
ENST00000468310.1
 PRKCZ
 protein kinase C, zeta
chr15_+_40532058 0.43 ENST00000260404.4
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_28124903 0.43 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH
 parathyroid hormone-like hormone
chr8_+_32405785 0.42 ENST00000287842.3
 NRG1
 neuregulin 1
chr5_+_66124590 0.41 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr19_+_38755042 0.41 ENST00000301244.7
 SPINT2
 serine peptidase inhibitor, Kunitz type, 2
chr19_-_16045220 0.41 ENST00000326742.8
 CYP4F11
 cytochrome P450, family 4, subfamily F, polypeptide 11
chr8_+_32405728 0.40 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
 NRG1
 neuregulin 1
chr8_-_21988558 0.39 ENST00000312841.8
 HR
 hair growth associated
chr1_+_151483855 0.39 ENST00000427934.2
ENST00000271636.7
 CGN
 cingulin
chr11_+_1860200 0.37 ENST00000381911.1
 TNNI2
 troponin I type 2 (skeletal, fast)
chr14_+_21525981 0.36 ENST00000308227.2
 RNASE8
 ribonuclease, RNase A family, 8
chr19_+_38755203 0.36 ENST00000587090.1
ENST00000454580.3
 SPINT2
 serine peptidase inhibitor, Kunitz type, 2
chr1_+_13910479 0.35 ENST00000509009.1
 PDPN
 podoplanin
chr14_+_21510385 0.33 ENST00000298690.4
 RNASE7
 ribonuclease, RNase A family, 7
chr13_+_78109804 0.31 ENST00000535157.1
 SCEL
 sciellin
chr13_+_78109884 0.31 ENST00000377246.3
ENST00000349847.3
 SCEL
 sciellin
chr12_-_52828147 0.30 ENST00000252245.5
 KRT75
 keratin 75
chr17_-_46507537 0.29 ENST00000336915.6
 SKAP1
 src kinase associated phosphoprotein 1
chr6_-_13487825 0.29 ENST00000603223.1
 GFOD1
 glucose-fructose oxidoreductase domain containing 1
chr1_+_13910757 0.29 ENST00000376061.4
ENST00000513143.1
 PDPN
 podoplanin
chr1_+_156254070 0.29 ENST00000405535.2
ENST00000456810.1
 TMEM79
 transmembrane protein 79
chr1_+_13910194 0.28 ENST00000376057.4
ENST00000510906.1
 PDPN
 podoplanin
chr6_-_13487784 0.28 ENST00000379287.3
 GFOD1
 glucose-fructose oxidoreductase domain containing 1
chr3_+_167453493 0.27 ENST00000295777.5
ENST00000472747.2
 SERPINI1
 serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr6_+_121756809 0.27 ENST00000282561.3
 GJA1
 gap junction protein, alpha 1, 43kDa
chr14_+_75745477 0.27 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
 FOS
 FBJ murine osteosarcoma viral oncogene homolog
chr17_+_34431212 0.26 ENST00000394495.1
 CCL4
 chemokine (C-C motif) ligand 4
chr8_-_144655141 0.25 ENST00000398882.3
 MROH6
 maestro heat-like repeat family member 6
chr11_+_120081475 0.25 ENST00000328965.4
 OAF
 OAF homolog (Drosophila)
chr17_+_34430980 0.24 ENST00000250151.4
 CCL4
 chemokine (C-C motif) ligand 4
chr17_+_47572647 0.24 ENST00000172229.3
 NGFR
 nerve growth factor receptor
chr14_+_61995722 0.24 ENST00000556347.1
 RP11-47I22.4
 RP11-47I22.4
chr15_+_90319557 0.23 ENST00000341735.3
 MESP2
 mesoderm posterior 2 homolog (mouse)
chr15_+_89181974 0.23 ENST00000306072.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr1_-_25256368 0.23 ENST00000308873.6
 RUNX3
 runt-related transcription factor 3
chr3_-_182880541 0.22 ENST00000470251.1
ENST00000265598.3
 LAMP3
 lysosomal-associated membrane protein 3
chr1_-_153521714 0.22 ENST00000368713.3
 S100A3
 S100 calcium binding protein A3
chr2_+_68962014 0.22 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr4_+_120133791 0.21 ENST00000274030.6
 USP53
 ubiquitin specific peptidase 53
chr8_+_123793633 0.21 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr17_+_30814707 0.21 ENST00000584792.1
 CDK5R1
 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_-_54281491 0.21 ENST00000381405.4
 ESM1
 endothelial cell-specific molecule 1
chr15_+_89182178 0.21 ENST00000559876.1
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr12_+_19358228 0.21 ENST00000424268.1
ENST00000543806.1
 PLEKHA5
 pleckstrin homology domain containing, family A member 5
chrX_+_135618258 0.20 ENST00000440515.1
ENST00000456412.1
 VGLL1
 vestigial like 1 (Drosophila)
chr15_+_88120158 0.20 ENST00000560153.1
 LINC00052
 long intergenic non-protein coding RNA 52
chrX_+_56259316 0.20 ENST00000468660.1
 KLF8
 Kruppel-like factor 8
chr8_+_104831472 0.19 ENST00000262231.10
ENST00000507740.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr17_-_27229948 0.19 ENST00000426464.2
 DHRS13
 dehydrogenase/reductase (SDR family) member 13
chr5_-_176836577 0.18 ENST00000253496.3
 F12
 coagulation factor XII (Hageman factor)
chr1_+_153746683 0.18 ENST00000271857.2
 SLC27A3
 solute carrier family 27 (fatty acid transporter), member 3
chr12_-_121342170 0.18 ENST00000353487.2
 SPPL3
 signal peptide peptidase like 3
chr3_+_142315225 0.17 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1
 plastin 1
chr17_-_27230035 0.17 ENST00000378895.4
ENST00000394901.3
 DHRS13
 dehydrogenase/reductase (SDR family) member 13
chr14_-_91526462 0.17 ENST00000536315.2
 RPS6KA5
 ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr5_-_54281407 0.16 ENST00000381403.4
 ESM1
 endothelial cell-specific molecule 1
chr10_-_131762105 0.16 ENST00000368648.3
ENST00000355311.5
 EBF3
 early B-cell factor 3
chr20_-_22565101 0.16 ENST00000419308.2
 FOXA2
 forkhead box A2
chr17_+_55183261 0.16 ENST00000576295.1
 AKAP1
 A kinase (PRKA) anchor protein 1
chrX_-_128788914 0.16 ENST00000429967.1
ENST00000307484.6
 APLN
 apelin
chr7_-_27135591 0.16 ENST00000343060.4
ENST00000355633.5
 HOXA1
 homeobox A1
chr3_+_49726932 0.15 ENST00000327697.6
ENST00000432042.1
ENST00000454491.1
 RNF123
 ring finger protein 123
chr16_-_69385681 0.15 ENST00000288025.3
 TMED6
 transmembrane emp24 protein transport domain containing 6
chr2_+_42275153 0.15 ENST00000294964.5
 PKDCC
 protein kinase domain containing, cytoplasmic
chr11_-_58345569 0.15 ENST00000528954.1
ENST00000528489.1
 LPXN
 leupaxin
chr11_-_7847519 0.15 ENST00000328375.1
 OR5P3
 olfactory receptor, family 5, subfamily P, member 3
chr15_+_89182156 0.15 ENST00000379224.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr5_-_134914673 0.15 ENST00000512158.1
 CXCL14
 chemokine (C-X-C motif) ligand 14
chrX_-_130423200 0.15 ENST00000361420.3
 IGSF1
 immunoglobulin superfamily, member 1
chr17_+_37894179 0.14 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
 GRB7
 growth factor receptor-bound protein 7
chr7_-_100253993 0.14 ENST00000461605.1
ENST00000160382.5
 ACTL6B
 actin-like 6B
chr9_-_96717654 0.14 ENST00000253968.6
 BARX1
 BARX homeobox 1
chrX_+_16804544 0.14 ENST00000380122.5
ENST00000398155.4
 TXLNG
 taxilin gamma
chr1_-_11042094 0.13 ENST00000377004.4
ENST00000377008.4
 C1orf127
 chromosome 1 open reading frame 127
chr12_+_50898881 0.13 ENST00000301180.5
 DIP2B
 DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr11_+_19138670 0.13 ENST00000446113.2
ENST00000399351.3
 ZDHHC13
 zinc finger, DHHC-type containing 13
chr19_-_41934635 0.13 ENST00000321702.2
 B3GNT8
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr1_-_204329013 0.13 ENST00000272203.3
ENST00000414478.1
 PLEKHA6
 pleckstrin homology domain containing, family A member 6
chr7_-_138666053 0.13 ENST00000440172.1
ENST00000422774.1
 KIAA1549
 KIAA1549
chr1_-_44482979 0.13 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr18_-_28742813 0.13 ENST00000257197.3
ENST00000257198.5
 DSC1
 desmocollin 1
chr2_-_56150184 0.12 ENST00000394554.1
 EFEMP1
 EGF containing fibulin-like extracellular matrix protein 1
chr12_-_18890940 0.12 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
 PLCZ1
 phospholipase C, zeta 1
chr4_-_110651111 0.12 ENST00000502283.1
 PLA2G12A
 phospholipase A2, group XIIA
chr6_+_30294612 0.12 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
 TRIM39
 tripartite motif containing 39
chr11_+_35198118 0.12 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
 CD44
 CD44 molecule (Indian blood group)
chr7_-_43965937 0.12 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
 URGCP
 upregulator of cell proliferation
chr11_-_128737163 0.12 ENST00000324003.3
ENST00000392665.2
 KCNJ1
 potassium inwardly-rectifying channel, subfamily J, member 1
chr6_-_30043539 0.11 ENST00000376751.3
ENST00000244360.6
 RNF39
 ring finger protein 39
chr19_-_49622348 0.11 ENST00000408991.2
 C19orf73
 chromosome 19 open reading frame 73
chrX_-_130423386 0.11 ENST00000370903.3
 IGSF1
 immunoglobulin superfamily, member 1
chr15_+_35270552 0.11 ENST00000391457.2
 AC114546.1
 HCG37415; PRO1914; Uncharacterized protein
chr11_-_128737259 0.11 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
 KCNJ1
 potassium inwardly-rectifying channel, subfamily J, member 1
chr12_+_7055767 0.11 ENST00000447931.2
 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
chr2_-_129076151 0.11 ENST00000259241.6
 HS6ST1
 heparan sulfate 6-O-sulfotransferase 1
chr7_+_107220660 0.11 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
 BCAP29
 B-cell receptor-associated protein 29
chr19_+_10397648 0.11 ENST00000340992.4
ENST00000393717.2
 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chrX_-_49056635 0.11 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
 SYP
 synaptophysin
chr11_-_34535297 0.11 ENST00000532417.1
 ELF5
 E74-like factor 5 (ets domain transcription factor)
chr11_+_34643600 0.11 ENST00000530286.1
ENST00000533754.1
 EHF
 ets homologous factor
chr3_+_14860831 0.11 ENST00000543601.1
 FGD5
 FYVE, RhoGEF and PH domain containing 5
chr1_+_165513231 0.10 ENST00000294818.1
 LRRC52
 leucine rich repeat containing 52
chr11_-_67415048 0.10 ENST00000529256.1
 ACY3
 aspartoacylase (aminocyclase) 3
chr7_-_71801980 0.10 ENST00000329008.5
 CALN1
 calneuron 1
chr11_-_123525289 0.10 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
 SCN3B
 sodium channel, voltage-gated, type III, beta subunit
chr11_-_59383617 0.10 ENST00000263847.1
 OSBP
 oxysterol binding protein
chr4_-_40631859 0.10 ENST00000295971.7
ENST00000319592.4
 RBM47
 RNA binding motif protein 47
chr1_-_207095324 0.10 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
 FAIM3
 Fas apoptotic inhibitory molecule 3
chr6_-_45983549 0.10 ENST00000544153.1
 CLIC5
 chloride intracellular channel 5
chr16_-_11350036 0.10 ENST00000332029.2
 SOCS1
 suppressor of cytokine signaling 1
chr11_+_58390132 0.10 ENST00000361987.4
 CNTF
 ciliary neurotrophic factor
chr11_-_72385437 0.10 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
 PDE2A
 phosphodiesterase 2A, cGMP-stimulated
chr7_-_142120321 0.10 ENST00000390377.1
 TRBV7-7
 T cell receptor beta variable 7-7
chr6_+_30295036 0.10 ENST00000376659.5
ENST00000428555.1
 TRIM39
 tripartite motif containing 39
chr1_+_93544791 0.09 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
 MTF2
 metal response element binding transcription factor 2
chr16_-_2031464 0.09 ENST00000356120.4
ENST00000354249.4
 NOXO1
 NADPH oxidase organizer 1
chr17_+_77020224 0.09 ENST00000339142.2
 C1QTNF1
 C1q and tumor necrosis factor related protein 1
chr1_+_93544821 0.09 ENST00000370303.4
 MTF2
 metal response element binding transcription factor 2
chr17_+_74372662 0.09 ENST00000591651.1
ENST00000545180.1
 SPHK1
 sphingosine kinase 1
chr17_+_77020325 0.09 ENST00000311661.4
 C1QTNF1
 C1q and tumor necrosis factor related protein 1
chr17_-_61996192 0.09 ENST00000392824.4
 CSHL1
 chorionic somatomammotropin hormone-like 1
chr17_-_74533963 0.09 ENST00000293230.5
 CYGB
 cytoglobin
chr12_+_81101277 0.09 ENST00000228641.3
 MYF6
 myogenic factor 6 (herculin)
chr14_+_24600484 0.09 ENST00000267426.5
 FITM1
 fat storage-inducing transmembrane protein 1
chr17_-_1588101 0.09 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
 PRPF8
 pre-mRNA processing factor 8
chr19_+_10397621 0.09 ENST00000380770.3
 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr16_-_4465886 0.09 ENST00000539968.1
 CORO7
 coronin 7
chr1_+_27189631 0.09 ENST00000339276.4
 SFN
 stratifin
chr2_+_96991935 0.09 ENST00000361124.4
ENST00000420728.1
ENST00000542887.1
 ITPRIPL1
 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr19_-_4302375 0.08 ENST00000600114.1
ENST00000600349.1
ENST00000595645.1
ENST00000301272.2
 TMIGD2
 transmembrane and immunoglobulin domain containing 2
chr11_-_5248294 0.08 ENST00000335295.4
 HBB
 hemoglobin, beta
chr3_-_49142504 0.08 ENST00000306125.6
ENST00000420147.2
 QARS
 glutaminyl-tRNA synthetase
chr11_-_34535332 0.08 ENST00000257832.2
ENST00000429939.2
 ELF5
 E74-like factor 5 (ets domain transcription factor)
chr2_+_11696464 0.08 ENST00000234142.5
 GREB1
 growth regulation by estrogen in breast cancer 1
chr20_+_35201993 0.08 ENST00000373872.4
 TGIF2
 TGFB-induced factor homeobox 2
chrX_-_11445856 0.08 ENST00000380736.1
 ARHGAP6
 Rho GTPase activating protein 6
chr2_+_171673417 0.08 ENST00000344257.5
 GAD1
 glutamate decarboxylase 1 (brain, 67kDa)
chr19_+_41949054 0.08 ENST00000378187.2
 C19orf69
 chromosome 19 open reading frame 69
chr20_+_52105495 0.08 ENST00000439873.2
 AL354993.1
 Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr10_+_135340859 0.08 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
 CYP2E1
 cytochrome P450, family 2, subfamily E, polypeptide 1
chr1_+_15736359 0.08 ENST00000375980.4
 EFHD2
 EF-hand domain family, member D2
chr1_-_205744205 0.08 ENST00000446390.2
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr3_-_61237050 0.07 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
 FHIT
 fragile histidine triad
chr2_+_171571827 0.07 ENST00000375281.3
 SP5
 Sp5 transcription factor
chr17_-_39324424 0.07 ENST00000391356.2
 KRTAP4-3
 keratin associated protein 4-3
chr3_-_52443799 0.07 ENST00000470173.1
ENST00000296288.5
 BAP1
 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr2_+_171673072 0.07 ENST00000358196.3
ENST00000375272.1
 GAD1
 glutamate decarboxylase 1 (brain, 67kDa)
chr12_+_7055631 0.07 ENST00000543115.1
ENST00000399448.1
 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
chr4_+_81118647 0.07 ENST00000415738.2
 PRDM8
 PR domain containing 8
chr16_-_50715196 0.07 ENST00000423026.2
 SNX20
 sorting nexin 20
chr3_+_134514093 0.07 ENST00000398015.3
 EPHB1
 EPH receptor B1
chr21_+_30502806 0.07 ENST00000399928.1
ENST00000399926.1
 MAP3K7CL
 MAP3K7 C-terminal like
chr3_-_49142178 0.07 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
 QARS
 glutaminyl-tRNA synthetase
chr17_+_77020146 0.07 ENST00000579760.1
 C1QTNF1
 C1q and tumor necrosis factor related protein 1
chr22_+_38597889 0.07 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr6_+_167536230 0.07 ENST00000341935.5
ENST00000349984.4
 CCR6
 chemokine (C-C motif) receptor 6
chr17_-_46703826 0.07 ENST00000550387.1
ENST00000311177.5
 HOXB9
 homeobox B9
chr21_-_46962379 0.07 ENST00000311124.4
ENST00000380010.4
 SLC19A1
 solute carrier family 19 (folate transporter), member 1
chr17_+_35849937 0.07 ENST00000394389.4
 DUSP14
 dual specificity phosphatase 14
chr1_+_171750776 0.07 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
 METTL13
 methyltransferase like 13
chr3_-_197024394 0.07 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
 DLG1
 discs, large homolog 1 (Drosophila)
chr3_+_14860469 0.07 ENST00000285046.5
 FGD5
 FYVE, RhoGEF and PH domain containing 5
chr2_+_189156638 0.07 ENST00000410051.1
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr17_-_7297833 0.07 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
chr8_+_104831554 0.07 ENST00000408894.2
 RIMS2
 regulating synaptic membrane exocytosis 2
chrX_-_130423240 0.06 ENST00000370910.1
ENST00000370901.4
 IGSF1
 immunoglobulin superfamily, member 1
chr2_+_242127924 0.06 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
 ANO7
 anoctamin 7
chr3_+_184080790 0.06 ENST00000430783.1
 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
chr2_+_191334212 0.06 ENST00000444317.1
ENST00000535751.1
 MFSD6
 major facilitator superfamily domain containing 6
chr4_-_120133661 0.06 ENST00000503243.1
ENST00000326780.3
 RP11-455G16.1
 Uncharacterized protein
chr20_-_32891151 0.06 ENST00000217426.2
 AHCY
 adenosylhomocysteinase
chr4_+_57371509 0.06 ENST00000360096.2
 ARL9
 ADP-ribosylation factor-like 9
chr16_+_66400533 0.06 ENST00000341529.3
 CDH5
 cadherin 5, type 2 (vascular endothelium)
chr9_+_4662282 0.06 ENST00000381883.2
 PPAPDC2
 phosphatidic acid phosphatase type 2 domain containing 2
chr11_+_74660278 0.06 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
 SPCS2
 signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr2_-_56150910 0.06 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
 EFEMP1
 EGF containing fibulin-like extracellular matrix protein 1
chr17_-_26898516 0.06 ENST00000543734.1
ENST00000395346.2
 PIGS
 phosphatidylinositol glycan anchor biosynthesis, class S
chr2_+_29336855 0.06 ENST00000404424.1
 CLIP4
 CAP-GLY domain containing linker protein family, member 4
chr1_-_85725316 0.06 ENST00000344356.5
ENST00000471115.1
 C1orf52
 chromosome 1 open reading frame 52
chr19_+_53761545 0.06 ENST00000341702.3
 VN1R2
 vomeronasal 1 receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 0.9 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.2 0.8 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.5 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 0.5 GO:0035627 ceramide transport(GO:0035627)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.4 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.1 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.2 GO:0021718 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.2 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.7 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.6 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.0 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.0 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.0 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 0.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.5 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.0 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling