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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for TEAD3_TEAD1

Z-value: 0.38

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Transcription factors associated with TEAD3_TEAD1

Gene Symbol Gene ID Gene Info
TEAD3
ENSG00000007866.14 TEAD3
TEAD1
ENSG00000187079.10 TEAD1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD3hg19_v2_chr6_-_35464727_35464738,
hg19_v2_chr6_-_35464817_35464894		0.157.2e-01Click!
TEAD1hg19_v2_chr11_+_12766583_12766592,
hg19_v2_chr11_+_12696102_12696164		0.147.4e-01Click!

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_132272504 1.70 ENST00000367976.3
 CTGF
 connective tissue growth factor
chr5_-_39425068 1.48 ENST00000515700.1
ENST00000339788.6
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr19_+_45409011 1.30 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
 APOE
 apolipoprotein E
chr19_+_34972543 1.28 ENST00000590071.2
 WTIP
 Wilms tumor 1 interacting protein
chr8_-_108510224 1.28 ENST00000517746.1
ENST00000297450.3
 ANGPT1
 angiopoietin 1
chr1_-_1293904 1.13 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
 MXRA8
 matrix-remodelling associated 8
chr11_-_111781454 1.12 ENST00000533280.1
 CRYAB
 crystallin, alpha B
chr16_+_29823427 1.00 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
 PRRT2
 proline-rich transmembrane protein 2
chr3_-_112360116 0.93 ENST00000206423.3
ENST00000439685.2
 CCDC80
 coiled-coil domain containing 80
chr9_-_139891165 0.87 ENST00000494426.1
 CLIC3
 chloride intracellular channel 3
chr16_+_29823552 0.75 ENST00000300797.6
 PRRT2
 proline-rich transmembrane protein 2
chr12_-_96184533 0.73 ENST00000343702.4
ENST00000344911.4
 NTN4
 netrin 4
chr16_+_30907927 0.69 ENST00000279804.2
ENST00000395019.3
 CTF1
 cardiotrophin 1
chr9_+_118916082 0.68 ENST00000328252.3
 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
chr5_-_55290773 0.66 ENST00000502326.3
ENST00000381298.2
 IL6ST
 interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr5_-_39425290 0.66 ENST00000545653.1
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_-_186733363 0.66 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2
chr3_-_114343039 0.64 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr5_-_39425222 0.64 ENST00000320816.6
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr8_+_70378852 0.64 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
 SULF1
 sulfatase 1
chr11_-_111781554 0.62 ENST00000526167.1
ENST00000528961.1
 CRYAB
 crystallin, alpha B
chr4_-_175443943 0.61 ENST00000296522.6
 HPGD
 hydroxyprostaglandin dehydrogenase 15-(NAD)
chr15_+_33010175 0.61 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
 GREM1
 gremlin 1, DAN family BMP antagonist
chr12_-_7245125 0.60 ENST00000542285.1
ENST00000540610.1
 C1R
 complement component 1, r subcomponent
chr11_-_111781610 0.57 ENST00000525823.1
 CRYAB
 crystallin, alpha B
chr11_-_111782696 0.57 ENST00000227251.3
ENST00000526180.1
 CRYAB
 crystallin, alpha B
chr12_-_47219733 0.57 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
 SLC38A4
 solute carrier family 38, member 4
chr10_-_90712520 0.56 ENST00000224784.6
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr16_+_30387141 0.55 ENST00000566955.1
 MYLPF
 myosin light chain, phosphorylatable, fast skeletal muscle
chr8_-_120605194 0.55 ENST00000522167.1
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr11_-_111782484 0.54 ENST00000533971.1
 CRYAB
 crystallin, alpha B
chr20_+_35169885 0.54 ENST00000279022.2
ENST00000346786.2
 MYL9
 myosin, light chain 9, regulatory
chr18_-_3247084 0.53 ENST00000609924.1
 RP13-270P17.3
 RP13-270P17.3
chr2_+_210444748 0.53 ENST00000392194.1
 MAP2
 microtubule-associated protein 2
chr20_+_33146510 0.52 ENST00000397709.1
 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
chr14_+_76044934 0.51 ENST00000238667.4
 FLVCR2
 feline leukemia virus subgroup C cellular receptor family, member 2
chr1_+_78354297 0.51 ENST00000334785.7
 NEXN
 nexilin (F actin binding protein)
chr3_-_191000172 0.51 ENST00000427544.2
 UTS2B
 urotensin 2B
chr15_-_48937982 0.48 ENST00000316623.5
 FBN1
 fibrillin 1
chr13_+_32605437 0.47 ENST00000380250.3
 FRY
 furry homolog (Drosophila)
chr15_+_62853562 0.46 ENST00000561311.1
 TLN2
 talin 2
chr16_-_74455290 0.45 ENST00000339953.5
 CLEC18B
 C-type lectin domain family 18, member B
chr5_+_131630117 0.45 ENST00000200652.3
 SLC22A4
 solute carrier family 22 (organic cation/zwitterion transporter), member 4
chr11_+_46316677 0.45 ENST00000534787.1
 CREB3L1
 cAMP responsive element binding protein 3-like 1
chr1_-_3447967 0.44 ENST00000294599.4
 MEGF6
 multiple EGF-like-domains 6
chr11_+_58390132 0.44 ENST00000361987.4
 CNTF
 ciliary neurotrophic factor
chr19_-_44388116 0.44 ENST00000587539.1
 ZNF404
 zinc finger protein 404
chr1_+_114522049 0.44 ENST00000369551.1
ENST00000320334.4
 OLFML3
 olfactomedin-like 3
chr17_-_39093672 0.43 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23
 keratin 23 (histone deacetylase inducible)
chr15_+_41549105 0.42 ENST00000560965.1
 CHP1
 calcineurin-like EF-hand protein 1
chr11_+_46299199 0.40 ENST00000529193.1
ENST00000288400.3
 CREB3L1
 cAMP responsive element binding protein 3-like 1
chr19_-_51472031 0.40 ENST00000391808.1
 KLK6
 kallikrein-related peptidase 6
chr1_+_78354175 0.40 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
 NEXN
 nexilin (F actin binding protein)
chr1_+_150229554 0.39 ENST00000369111.4
 CA14
 carbonic anhydrase XIV
chr16_-_122619 0.39 ENST00000262316.6
 RHBDF1
 rhomboid 5 homolog 1 (Drosophila)
chr19_-_51472222 0.39 ENST00000376851.3
 KLK6
 kallikrein-related peptidase 6
chr4_-_186877502 0.39 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
 SORBS2
 sorbin and SH3 domain containing 2
chr11_+_130542851 0.39 ENST00000317019.2
 C11orf44
 chromosome 11 open reading frame 44
chr14_-_60337684 0.37 ENST00000267484.5
 RTN1
 reticulon 1
chr8_+_97597148 0.37 ENST00000521590.1
 SDC2
 syndecan 2
chr2_-_190044480 0.35 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr11_-_47470703 0.35 ENST00000298854.2
 RAPSN
 receptor-associated protein of the synapse
chr3_-_119379719 0.35 ENST00000493094.1
 POPDC2
 popeye domain containing 2
chr6_-_128841503 0.35 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
 PTPRK
 protein tyrosine phosphatase, receptor type, K
chr9_-_20622478 0.35 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_47470591 0.34 ENST00000524487.1
 RAPSN
 receptor-associated protein of the synapse
chr9_-_73483958 0.33 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
chr15_+_63334831 0.32 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
 TPM1
 tropomyosin 1 (alpha)
chr3_-_119379427 0.32 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
 POPDC2
 popeye domain containing 2
chr8_-_38325219 0.32 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
 FGFR1
 fibroblast growth factor receptor 1
chr17_-_27949911 0.31 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
 CORO6
 coronin 6
chr19_-_14048804 0.31 ENST00000254320.3
ENST00000586075.1
 PODNL1
 podocan-like 1
chr11_+_48002076 0.30 ENST00000418331.2
ENST00000440289.2
 PTPRJ
 protein tyrosine phosphatase, receptor type, J
chr2_-_111230393 0.29 ENST00000447537.2
ENST00000413601.2
 LIMS3L
LIMS3L
 LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
LIM and senescent cell antigen-like domains 3-like
chr11_-_47470682 0.29 ENST00000529341.1
ENST00000352508.3
 RAPSN
 receptor-associated protein of the synapse
chr10_-_17659234 0.28 ENST00000466335.1
 PTPLA
 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_-_63328817 0.28 ENST00000228705.6
 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_108881012 0.28 ENST00000343882.6
 FOXO3
 forkhead box O3
chr4_-_186877806 0.28 ENST00000355634.5
 SORBS2
 sorbin and SH3 domain containing 2
chr7_-_150946015 0.27 ENST00000262188.8
 SMARCD3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr13_-_67804445 0.27 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
 PCDH9
 protocadherin 9
chr1_+_196621156 0.27 ENST00000359637.2
 CFH
 complement factor H
chr1_-_201915590 0.26 ENST00000367288.4
 LMOD1
 leiomodin 1 (smooth muscle)
chr13_-_33760216 0.26 ENST00000255486.4
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr2_+_110656005 0.26 ENST00000437679.2
 LIMS3
 LIM and senescent cell antigen-like domains 3
chr1_+_196621002 0.26 ENST00000367429.4
ENST00000439155.2
 CFH
 complement factor H
chr3_-_9994021 0.26 ENST00000411976.2
ENST00000412055.1
 PRRT3
 proline-rich transmembrane protein 3
chr11_+_65190245 0.26 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
 NEAT1
 nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr2_-_175499294 0.25 ENST00000392547.2
 WIPF1
 WAS/WASL interacting protein family, member 1
chr8_+_38831683 0.25 ENST00000302495.4
 HTRA4
 HtrA serine peptidase 4
chr7_-_137686791 0.25 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
 CREB3L2
 cAMP responsive element binding protein 3-like 2
chr6_-_111804905 0.25 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr22_+_24577183 0.24 ENST00000358321.3
 SUSD2
 sushi domain containing 2
chr11_-_62521614 0.24 ENST00000527994.1
ENST00000394807.3
 ZBTB3
 zinc finger and BTB domain containing 3
chr17_+_20059358 0.24 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
 SPECC1
 sperm antigen with calponin homology and coiled-coil domains 1
chr9_+_18474098 0.24 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
 ADAMTSL1
 ADAMTS-like 1
chr14_-_89021077 0.23 ENST00000556564.1
 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
chr4_-_186732048 0.23 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
 SORBS2
 sorbin and SH3 domain containing 2
chrX_+_99899180 0.23 ENST00000373004.3
 SRPX2
 sushi-repeat containing protein, X-linked 2
chr6_-_152489484 0.23 ENST00000354674.4
ENST00000539504.1
 SYNE1
 spectrin repeat containing, nuclear envelope 1
chr18_-_25616519 0.23 ENST00000399380.3
 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
chr16_-_57570450 0.23 ENST00000258214.2
 CCDC102A
 coiled-coil domain containing 102A
chr12_-_7281469 0.23 ENST00000542370.1
ENST00000266560.3
 RBP5
 retinol binding protein 5, cellular
chr16_+_30386098 0.23 ENST00000322861.7
 MYLPF
 myosin light chain, phosphorylatable, fast skeletal muscle
chr9_+_72658490 0.23 ENST00000377182.4
 MAMDC2
 MAM domain containing 2
chr18_+_39535152 0.22 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
 PIK3C3
 phosphatidylinositol 3-kinase, catalytic subunit type 3
chr10_-_106240032 0.22 ENST00000447860.1
 RP11-127O4.3
 RP11-127O4.3
chr2_+_102759199 0.22 ENST00000409288.1
ENST00000410023.1
 IL1R1
 interleukin 1 receptor, type I
chr17_+_73717407 0.22 ENST00000579662.1
 ITGB4
 integrin, beta 4
chrX_-_83757399 0.22 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
 HDX
 highly divergent homeobox
chr12_-_122241812 0.21 ENST00000538335.1
 AC084018.1
 AC084018.1
chr11_-_1785139 0.21 ENST00000236671.2
 CTSD
 cathepsin D
chr4_+_166300084 0.21 ENST00000402744.4
 CPE
 carboxypeptidase E
chr7_+_134430212 0.21 ENST00000436461.2
 CALD1
 caldesmon 1
chr13_+_76210448 0.21 ENST00000377499.5
 LMO7
 LIM domain 7
chr1_+_74701062 0.21 ENST00000326637.3
 TNNI3K
 TNNI3 interacting kinase
chr17_+_73717516 0.21 ENST00000200181.3
ENST00000339591.3
 ITGB4
 integrin, beta 4
chr19_-_14049184 0.21 ENST00000339560.5
 PODNL1
 podocan-like 1
chr3_+_9944492 0.20 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
 IL17RE
 interleukin 17 receptor E
chr6_+_123038689 0.20 ENST00000354275.2
ENST00000368446.1
 PKIB
 protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr17_+_73717551 0.19 ENST00000450894.3
 ITGB4
 integrin, beta 4
chr13_-_86373536 0.19 ENST00000400286.2
 SLITRK6
 SLIT and NTRK-like family, member 6
chrX_-_142722897 0.19 ENST00000338017.4
 SLITRK4
 SLIT and NTRK-like family, member 4
chr19_-_6375860 0.19 ENST00000245810.1
 PSPN
 persephin
chr17_-_21156578 0.19 ENST00000399011.2
ENST00000468196.1
 C17orf103
 chromosome 17 open reading frame 103
chr2_+_228029281 0.19 ENST00000396578.3
 COL4A3
 collagen, type IV, alpha 3 (Goodpasture antigen)
chr12_+_80750134 0.19 ENST00000546620.1
 OTOGL
 otogelin-like
chr12_-_104443890 0.19 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
 GLT8D2
 glycosyltransferase 8 domain containing 2
chr3_+_38347427 0.19 ENST00000273173.4
 SLC22A14
 solute carrier family 22, member 14
chr16_-_72206034 0.19 ENST00000537465.1
ENST00000237353.10
 PMFBP1
 polyamine modulated factor 1 binding protein 1
chr11_-_62911693 0.19 ENST00000417740.1
ENST00000326192.5
 SLC22A24
 solute carrier family 22, member 24
chr16_-_31076332 0.18 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668
 zinc finger protein 668
chr8_-_91657740 0.18 ENST00000422900.1
 TMEM64
 transmembrane protein 64
chr2_+_228678550 0.18 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chr20_+_44044717 0.18 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
 PIGT
 phosphatidylinositol glycan anchor biosynthesis, class T
chr4_+_41614720 0.18 ENST00000509277.1
 LIMCH1
 LIM and calponin homology domains 1
chr10_+_99344071 0.18 ENST00000370647.4
ENST00000370646.4
 HOGA1
 4-hydroxy-2-oxoglutarate aldolase 1
chr5_-_95158644 0.18 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr17_-_79105734 0.18 ENST00000417379.1
 AATK
 apoptosis-associated tyrosine kinase
chr1_+_178310581 0.17 ENST00000462775.1
 RASAL2
 RAS protein activator like 2
chr16_+_69985083 0.17 ENST00000288040.6
ENST00000449317.2
 CLEC18A
 C-type lectin domain family 18, member A
chr5_+_140868717 0.17 ENST00000252087.1
 PCDHGC5
 protocadherin gamma subfamily C, 5
chr2_+_145780739 0.17 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
 TEX41
 testis expressed 41 (non-protein coding)
chr2_-_26864228 0.17 ENST00000288861.4
 CIB4
 calcium and integrin binding family member 4
chr5_+_42423872 0.17 ENST00000230882.4
ENST00000357703.3
 GHR
 growth hormone receptor
chr4_-_119274121 0.17 ENST00000296498.3
 PRSS12
 protease, serine, 12 (neurotrypsin, motopsin)
chr9_-_73736511 0.17 ENST00000377110.3
ENST00000377111.2
 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
chrX_+_48455866 0.17 ENST00000376729.5
ENST00000218056.5
 WDR13
 WD repeat domain 13
chr15_-_37391614 0.17 ENST00000219869.9
 MEIS2
 Meis homeobox 2
chr3_+_141043050 0.17 ENST00000509842.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr19_-_4043154 0.17 ENST00000535853.1
 AC016586.1
 AC016586.1
chr3_+_9944303 0.17 ENST00000421412.1
ENST00000295980.3
 IL17RE
 interleukin 17 receptor E
chr6_-_30899924 0.17 ENST00000359086.3
 SFTA2
 surfactant associated 2
chr16_+_70207686 0.16 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
 CLEC18C
 C-type lectin domain family 18, member C
chr2_-_183387430 0.16 ENST00000410103.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr9_+_131684562 0.16 ENST00000421063.2
 PHYHD1
 phytanoyl-CoA dioxygenase domain containing 1
chr8_+_38585704 0.16 ENST00000519416.1
ENST00000520615.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr19_+_45349630 0.16 ENST00000252483.5
 PVRL2
 poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr10_+_81891416 0.16 ENST00000372270.2
 PLAC9
 placenta-specific 9
chr6_+_30850697 0.16 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr4_-_70725856 0.16 ENST00000226444.3
 SULT1E1
 sulfotransferase family 1E, estrogen-preferring, member 1
chr11_+_22689648 0.16 ENST00000278187.3
 GAS2
 growth arrest-specific 2
chr5_-_146781153 0.16 ENST00000520473.1
 DPYSL3
 dihydropyrimidinase-like 3
chr7_-_100881041 0.16 ENST00000412417.1
ENST00000414035.1
 CLDN15
 claudin 15
chr5_+_49962772 0.16 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr3_-_62358690 0.16 ENST00000475839.1
 FEZF2
 FEZ family zinc finger 2
chr5_-_95158375 0.16 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX
 glutaredoxin (thioltransferase)
chr17_-_7145106 0.16 ENST00000577035.1
 GABARAP
 GABA(A) receptor-associated protein
chr15_+_43809797 0.16 ENST00000399453.1
ENST00000300231.5
 MAP1A
 microtubule-associated protein 1A
chr15_-_44069741 0.15 ENST00000319359.3
 ELL3
 elongation factor RNA polymerase II-like 3
chr5_+_112074029 0.15 ENST00000512211.2
 APC
 adenomatous polyposis coli
chr7_+_134464376 0.15 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr16_-_31076273 0.15 ENST00000426488.2
 ZNF668
 zinc finger protein 668
chr5_-_177423243 0.15 ENST00000308304.2
 PROP1
 PROP paired-like homeobox 1
chr19_+_15218180 0.15 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
 SYDE1
 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_+_43121698 0.15 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
 ZNF131
 zinc finger protein 131
chr12_-_14967095 0.15 ENST00000316048.2
 SMCO3
 single-pass membrane protein with coiled-coil domains 3
chr16_+_1578674 0.15 ENST00000253934.5
 TMEM204
 transmembrane protein 204
chr19_+_39903185 0.15 ENST00000409794.3
 PLEKHG2
 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr7_+_128470431 0.15 ENST00000325888.8
ENST00000346177.6
 FLNC
 filamin C, gamma
chr3_-_155394152 0.14 ENST00000494598.1
 PLCH1
 phospholipase C, eta 1
chr11_-_124190184 0.14 ENST00000357438.2
 OR8D2
 olfactory receptor, family 8, subfamily D, member 2
chr14_-_77495007 0.14 ENST00000238647.3
 IRF2BPL
 interferon regulatory factor 2 binding protein-like
chr10_-_92681033 0.14 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr13_+_46276441 0.14 ENST00000310521.1
ENST00000533564.1
 SPERT
 spermatid associated
chr21_+_17566643 0.14 ENST00000419952.1
ENST00000445461.2
 LINC00478
 long intergenic non-protein coding RNA 478
chr5_+_54455946 0.14 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
 GPX8
 glutathione peroxidase 8 (putative)
chr12_-_45307711 0.14 ENST00000333837.4
ENST00000551949.1
 NELL2
 NEL-like 2 (chicken)
chr16_+_69984810 0.14 ENST00000393701.2
ENST00000568461.1
 CLEC18A
 C-type lectin domain family 18, member A
chr9_-_113341985 0.14 ENST00000374469.1
 SVEP1
 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr5_+_118691706 0.14 ENST00000415806.2
 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
chr1_-_205290865 0.14 ENST00000367157.3
 NUAK2
 NUAK family, SNF1-like kinase, 2
chr1_-_76398077 0.13 ENST00000284142.6
 ASB17
 ankyrin repeat and SOCS box containing 17
chr7_+_134464414 0.13 ENST00000361901.2
 CALD1
 caldesmon 1
chr5_-_180688105 0.13 ENST00000327767.4
 TRIM52
 tripartite motif containing 52
chr8_-_57359131 0.13 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
 PENK
 proenkephalin
chr1_-_154474589 0.13 ENST00000304760.2
 SHE
 Src homology 2 domain containing E
chr18_-_3219847 0.13 ENST00000261606.7
 MYOM1
 myomesin 1
chr12_-_10151773 0.13 ENST00000298527.6
ENST00000348658.4
 CLEC1B
 C-type lectin domain family 1, member B
chr9_+_139873264 0.13 ENST00000446677.1
 PTGDS
 prostaglandin D2 synthase 21kDa (brain)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0035026 leading edge cell differentiation(GO:0035026)
0.6 1.7 GO:0034059 response to anoxia(GO:0034059)
0.4 1.3 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.3 1.0 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3 1.5 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.6 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 3.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.3 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.5 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 1.6 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.6 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.1 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.2 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.4 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.5 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 1.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.8 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0072229 nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.0 GO:1901631 positive regulation of presynaptic membrane organization(GO:1901631)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.0 GO:0003011 diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.4 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.2 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.0 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0071694 sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.0 GO:0031269 pseudopodium assembly(GO:0031269)
0.0 0.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 2.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 3.3 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.5 GO:0044754 autolysosome(GO:0044754)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.4 GO:0032059 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 0.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.6 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 2.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.1 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 2.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 1.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.0 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions