Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TFAP2B Links Ensembl NCBI GeneCards UniProt	ENSG00000008196.8	TFAP2B

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TFAP2B	hg19_v2_chr6_+_50786414_50786439	0.54	1.7e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr17_-_39677971	2.45	ENST00000393976.2	KRT15	keratin 15
chr1_+_160370344	2.02	ENST00000368061.2	VANGL2	VANGL planar cell polarity protein 2
chr16_+_68679193	1.95	ENST00000581171.1	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr1_-_153588334	1.91	ENST00000476873.1	S100A14	S100 calcium binding protein A14
chr16_+_22825475	1.87	ENST00000261374.3	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_209602771	1.74	ENST00000440276.1	MIR205HG	MIR205 host gene (non-protein coding)
chr16_+_68678892	1.74	ENST00000429102.2	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr1_+_209602609	1.63	ENST00000458250.1	MIR205HG	MIR205 host gene (non-protein coding)
chr19_-_19739007	1.55	ENST00000586703.1 ENST00000591042.1 ENST00000407877.3	LPAR2	lysophosphatidic acid receptor 2
chr15_+_101420028	1.55	ENST00000557963.1 ENST00000346623.6	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr14_+_65171315	1.40	ENST00000394691.1	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_120770686	1.38	ENST00000331393.4 ENST00000443124.1	EPB41L5	erythrocyte membrane protein band 4.1 like 5
chr8_-_21988558	1.33	ENST00000312841.8	HR	hair growth associated
chr6_-_136871957	1.24	ENST00000354570.3	MAP7	microtubule-associated protein 7
chr20_+_62327996	1.22	ENST00000369996.1	TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy
chr7_-_143105941	1.20	ENST00000275815.3	EPHA1	EPH receptor A1
chr6_+_54711533	1.20	ENST00000306858.7	FAM83B	family with sequence similarity 83, member B
chr18_+_33877654	1.19	ENST00000257209.4 ENST00000445677.1 ENST00000590592.1 ENST00000359247.4	FHOD3	formin homology 2 domain containing 3
chr16_+_81478775	1.07	ENST00000537098.3	CMIP	c-Maf inducing protein
chr19_-_55660561	1.06	ENST00000587758.1 ENST00000356783.5 ENST00000291901.8 ENST00000588426.1 ENST00000588147.1 ENST00000536926.1 ENST00000588981.1	TNNT1	troponin T type 1 (skeletal, slow)
chr7_+_16793160	1.06	ENST00000262067.4	TSPAN13	tetraspanin 13
chr16_-_68269971	1.05	ENST00000565858.1	ESRP2	epithelial splicing regulatory protein 2
chr16_+_67465016	0.97	ENST00000326152.5	HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2
chr1_+_2036149	0.97	ENST00000482686.1 ENST00000400920.1 ENST00000486681.1	PRKCZ	protein kinase C, zeta
chr19_+_7710774	0.95	ENST00000602355.1	STXBP2	syntaxin binding protein 2
chr1_+_1981890	0.92	ENST00000378567.3 ENST00000468310.1	PRKCZ	protein kinase C, zeta
chr1_+_233463507	0.86	ENST00000366623.3 ENST00000366624.3	MLK4	Mitogen-activated protein kinase kinase kinase MLK4
chr1_+_65613852	0.83	ENST00000327299.7	AK4	adenylate kinase 4
chr14_+_65171099	0.83	ENST00000247226.7	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_32042105	0.82	ENST00000457433.2 ENST00000441210.2	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr14_+_94640633	0.81	ENST00000304338.3	PPP4R4	protein phosphatase 4, regulatory subunit 4
chr22_-_20255212	0.81	ENST00000416372.1	RTN4R	reticulon 4 receptor
chr6_-_138428613	0.79	ENST00000421351.3	PERP	PERP, TP53 apoptosis effector
chr1_+_32042131	0.79	ENST00000271064.7 ENST00000537531.1	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr1_-_27286897	0.75	ENST00000320567.5	C1orf172	chromosome 1 open reading frame 172
chr5_+_36608422	0.75	ENST00000381918.3	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_+_3014217	0.72	ENST00000572045.1	KREMEN2	kringle containing transmembrane protein 2
chr1_-_9189229	0.71	ENST00000377411.4	GPR157	G protein-coupled receptor 157
chr1_+_152881014	0.71	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr12_-_89746173	0.70	ENST00000308385.6	DUSP6	dual specificity phosphatase 6
chr20_-_49639631	0.68	ENST00000424171.1 ENST00000439216.1 ENST00000371571.4	KCNG1	potassium voltage-gated channel, subfamily G, member 1
chr20_-_50808236	0.62	ENST00000361387.2	ZFP64	ZFP64 zinc finger protein
chr22_+_45072925	0.62	ENST00000006251.7	PRR5	proline rich 5 (renal)
chr16_+_2867228	0.62	ENST00000005995.3 ENST00000574813.1	PRSS21	protease, serine, 21 (testisin)
chr22_+_45072958	0.62	ENST00000403581.1	PRR5	proline rich 5 (renal)
chr19_+_7701985	0.61	ENST00000595950.1 ENST00000441779.2 ENST00000221283.5 ENST00000414284.2	STXBP2	syntaxin binding protein 2
chr2_-_220408430	0.60	ENST00000243776.6	CHPF	chondroitin polymerizing factor
chr17_-_4463856	0.60	ENST00000574584.1 ENST00000381550.3 ENST00000301395.3	GGT6	gamma-glutamyltransferase 6
chr10_+_48355024	0.59	ENST00000395702.2 ENST00000442001.1 ENST00000433077.1 ENST00000436850.1 ENST00000494156.1 ENST00000586537.1	ZNF488	zinc finger protein 488
chr11_-_7695437	0.59	ENST00000533558.1 ENST00000527542.1 ENST00000531096.1	CYB5R2	cytochrome b5 reductase 2
chr14_+_92980111	0.59	ENST00000216487.7 ENST00000557762.1	RIN3	Ras and Rab interactor 3
chr3_-_48470838	0.58	ENST00000358459.4 ENST00000358536.4	PLXNB1	plexin B1
chr11_-_7694684	0.58	ENST00000524790.1 ENST00000299497.9 ENST00000299498.6	CYB5R2	cytochrome b5 reductase 2
chrX_-_78622805	0.57	ENST00000373298.2	ITM2A	integral membrane protein 2A
chr16_+_2867164	0.57	ENST00000455114.1 ENST00000450020.3	PRSS21	protease, serine, 21 (testisin)
chr5_+_131409476	0.57	ENST00000296871.2	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr1_-_23886285	0.56	ENST00000374561.5	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr3_-_196756646	0.56	ENST00000439320.1 ENST00000296351.4 ENST00000296350.5	MFI2	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr8_-_144655141	0.56	ENST00000398882.3	MROH6	maestro heat-like repeat family member 6
chr13_-_76056250	0.54	ENST00000377636.3 ENST00000431480.2 ENST00000377625.2 ENST00000425511.1	TBC1D4	TBC1 domain family, member 4
chr5_-_150603679	0.54	ENST00000355417.2	CCDC69	coiled-coil domain containing 69
chr3_-_185216811	0.51	ENST00000421852.1	TMEM41A	transmembrane protein 41A
chr1_+_33207381	0.51	ENST00000401073.2	KIAA1522	KIAA1522
chr1_+_153746683	0.51	ENST00000271857.2	SLC27A3	solute carrier family 27 (fatty acid transporter), member 3
chr19_+_17858509	0.50	ENST00000594202.1 ENST00000252771.7 ENST00000389133.4	FCHO1	FCH domain only 1
chr19_+_17858547	0.50	ENST00000600676.1 ENST00000600209.1 ENST00000596309.1 ENST00000598539.1 ENST00000597474.1 ENST00000593385.1 ENST00000598067.1 ENST00000593833.1	FCHO1	FCH domain only 1
chr3_-_52090461	0.50	ENST00000296483.6 ENST00000495880.1	DUSP7	dual specificity phosphatase 7
chr8_+_123793633	0.50	ENST00000314393.4	ZHX2	zinc fingers and homeoboxes 2
chr9_+_116917807	0.49	ENST00000356083.3	COL27A1	collagen, type XXVII, alpha 1
chr22_-_46933067	0.49	ENST00000262738.3 ENST00000395964.1	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1
chr21_+_18885318	0.49	ENST00000400166.1	CXADR	coxsackie virus and adenovirus receptor
chr3_-_124839648	0.49	ENST00000430155.2	SLC12A8	solute carrier family 12, member 8
chr19_-_11689752	0.48	ENST00000592659.1 ENST00000592828.1 ENST00000218758.5 ENST00000412435.2	ACP5	acid phosphatase 5, tartrate resistant
chr12_-_31477072	0.48	ENST00000454658.2	FAM60A	family with sequence similarity 60, member A
chr2_-_73511559	0.47	ENST00000521871.1	FBXO41	F-box protein 41
chr9_+_133971909	0.47	ENST00000247291.3 ENST00000372302.1 ENST00000372300.1 ENST00000372298.1	AIF1L	allograft inflammatory factor 1-like
chr16_+_3014269	0.46	ENST00000575885.1 ENST00000571007.1 ENST00000319500.6	KREMEN2	kringle containing transmembrane protein 2
chr9_+_133971863	0.46	ENST00000372309.3	AIF1L	allograft inflammatory factor 1-like
chr8_+_56792377	0.46	ENST00000520220.2	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr8_+_56792355	0.46	ENST00000519728.1	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_-_39942940	0.46	ENST00000310706.5 ENST00000393931.3 ENST00000424457.1 ENST00000591690.1	JUP	junction plakoglobin
chr12_+_7060432	0.43	ENST00000318974.9 ENST00000456013.1	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_31902614	0.43	ENST00000596131.1	AC114494.1	HCG1787699; Uncharacterized protein
chr16_+_23847267	0.43	ENST00000321728.7	PRKCB	protein kinase C, beta
chr12_-_102224457	0.43	ENST00000549165.1 ENST00000549940.1 ENST00000392919.4	GNPTAB	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr1_-_147245484	0.42	ENST00000271348.2	GJA5	gap junction protein, alpha 5, 40kDa
chr12_+_6493406	0.42	ENST00000543190.1	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr6_-_3457256	0.42	ENST00000436008.2	SLC22A23	solute carrier family 22, member 23
chr1_+_55013889	0.41	ENST00000343744.2 ENST00000371316.3	ACOT11	acyl-CoA thioesterase 11
chr19_+_1067492	0.41	ENST00000586866.1	HMHA1	histocompatibility (minor) HA-1
chr19_+_1067144	0.41	ENST00000313093.2	HMHA1	histocompatibility (minor) HA-1
chr19_+_1067271	0.40	ENST00000536472.1 ENST00000590214.1	HMHA1	histocompatibility (minor) HA-1
chr5_-_174871136	0.40	ENST00000393752.2	DRD1	dopamine receptor D1
chr1_-_19283163	0.40	ENST00000455833.2	IFFO2	intermediate filament family orphan 2
chr19_-_42724261	0.39	ENST00000595337.1	DEDD2	death effector domain containing 2
chr1_-_54872059	0.39	ENST00000371320.3	SSBP3	single stranded DNA binding protein 3
chr12_+_6308881	0.38	ENST00000382518.1 ENST00000536586.1	CD9	CD9 molecule
chr17_+_1646130	0.38	ENST00000453066.1 ENST00000324015.3 ENST00000450523.2 ENST00000453723.1 ENST00000382061.4	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr17_-_73874654	0.38	ENST00000254816.2	TRIM47	tripartite motif containing 47
chr5_+_149737202	0.38	ENST00000451292.1 ENST00000377797.3 ENST00000445265.2 ENST00000323668.7 ENST00000439160.2 ENST00000394269.3 ENST00000427724.2 ENST00000504761.2 ENST00000513346.1 ENST00000515516.1	TCOF1	Treacher Collins-Franceschetti syndrome 1
chr1_+_45792541	0.38	ENST00000334815.3	HPDL	4-hydroxyphenylpyruvate dioxygenase-like
chr1_-_25291475	0.38	ENST00000338888.3 ENST00000399916.1	RUNX3	runt-related transcription factor 3
chr3_+_10857885	0.36	ENST00000254488.2 ENST00000454147.1	SLC6A11	solute carrier family 6 (neurotransmitter transporter), member 11
chrX_+_37545012	0.35	ENST00000378616.3	XK	X-linked Kx blood group (McLeod syndrome)
chrX_+_21392873	0.35	ENST00000379510.3	CNKSR2	connector enhancer of kinase suppressor of Ras 2
chr11_+_63606558	0.34	ENST00000350490.7 ENST00000502399.3	MARK2	MAP/microtubule affinity-regulating kinase 2
chr13_-_99852916	0.34	ENST00000426037.2 ENST00000445737.2	UBAC2-AS1	UBAC2 antisense RNA 1
chr16_+_81678957	0.34	ENST00000398040.4	CMIP	c-Maf inducing protein
chr4_-_1723040	0.33	ENST00000382936.3 ENST00000536901.1 ENST00000303277.2	TMEM129	transmembrane protein 129
chr1_-_15911510	0.33	ENST00000375826.3	AGMAT	agmatine ureohydrolase (agmatinase)
chr15_-_79383102	0.32	ENST00000558480.2 ENST00000419573.3	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr3_-_185216766	0.32	ENST00000296254.3	TMEM41A	transmembrane protein 41A
chr2_-_208030647	0.31	ENST00000309446.6	KLF7	Kruppel-like factor 7 (ubiquitous)
chr2_+_26915584	0.31	ENST00000302909.3	KCNK3	potassium channel, subfamily K, member 3
chr12_+_50451462	0.31	ENST00000447966.2	ASIC1	acid-sensing (proton-gated) ion channel 1
chr2_-_208634287	0.31	ENST00000295417.3	FZD5	frizzled family receptor 5
chrX_+_48916497	0.30	ENST00000496529.2 ENST00000376396.3 ENST00000422185.2 ENST00000603986.1 ENST00000536628.2	CCDC120	coiled-coil domain containing 120
chr1_+_32716840	0.30	ENST00000336890.5	LCK	lymphocyte-specific protein tyrosine kinase
chr3_+_125687987	0.30	ENST00000514116.1 ENST00000251776.4 ENST00000504401.1 ENST00000513830.1 ENST00000508088.1	ROPN1B	rhophilin associated tail protein 1B
chr8_-_8751068	0.29	ENST00000276282.6	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr6_-_35888905	0.29	ENST00000510290.1 ENST00000423325.2 ENST00000373822.1	SRPK1	SRSF protein kinase 1
chr10_-_35930219	0.29	ENST00000374694.1	FZD8	frizzled family receptor 8
chrX_+_131157290	0.29	ENST00000394334.2	MST4	Serine/threonine-protein kinase MST4
chr17_-_7760779	0.29	ENST00000335155.5 ENST00000575071.1	LSMD1	LSM domain containing 1
chr7_-_151329416	0.28	ENST00000418337.2	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_-_49149553	0.28	ENST00000084798.4	CA11	carbonic anhydrase XI
chrX_-_154033793	0.28	ENST00000369534.3 ENST00000413259.3	MPP1	membrane protein, palmitoylated 1, 55kDa
chr1_+_155178518	0.28	ENST00000316721.4	MTX1	metaxin 1
chr10_-_99094458	0.27	ENST00000371019.2	FRAT2	frequently rearranged in advanced T-cell lymphomas 2
chr12_-_122238913	0.27	ENST00000537157.1	AC084018.1	AC084018.1
chr6_+_33589161	0.27	ENST00000605930.1	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3
chr12_+_19282713	0.27	ENST00000299275.6 ENST00000539256.1 ENST00000538714.1	PLEKHA5	pleckstrin homology domain containing, family A member 5
chr10_+_103825080	0.27	ENST00000299238.5	HPS6	Hermansky-Pudlak syndrome 6
chr19_+_39989580	0.26	ENST00000596614.1 ENST00000205143.4	DLL3	delta-like 3 (Drosophila)
chrX_+_131157322	0.26	ENST00000481105.1 ENST00000354719.6 ENST00000394335.2	MST4	Serine/threonine-protein kinase MST4
chr6_-_35888824	0.26	ENST00000361690.3 ENST00000512445.1	SRPK1	SRSF protein kinase 1
chr19_+_30433372	0.26	ENST00000312051.6	URI1	URI1, prefoldin-like chaperone
chr8_-_143867946	0.25	ENST00000301263.4	LY6D	lymphocyte antigen 6 complex, locus D
chr5_+_141016969	0.25	ENST00000518856.1	RELL2	RELT-like 2
chr12_+_56414851	0.25	ENST00000547167.1	IKZF4	IKAROS family zinc finger 4 (Eos)
chr1_+_17575584	0.25	ENST00000375460.3	PADI3	peptidyl arginine deiminase, type III
chr19_+_19144384	0.25	ENST00000392335.2 ENST00000535612.1 ENST00000537263.1 ENST00000540707.1 ENST00000541725.1 ENST00000269932.6 ENST00000546344.1 ENST00000540792.1 ENST00000536098.1 ENST00000541898.1 ENST00000543877.1	ARMC6	armadillo repeat containing 6
chr21_-_47575481	0.25	ENST00000291670.5 ENST00000397748.1 ENST00000359679.2 ENST00000355384.2 ENST00000397746.3 ENST00000397743.1	FTCD	formimidoyltransferase cyclodeaminase
chr3_-_150481164	0.25	ENST00000312960.3	SIAH2	siah E3 ubiquitin protein ligase 2
chr14_+_94640671	0.24	ENST00000328839.3	PPP4R4	protein phosphatase 4, regulatory subunit 4
chr6_-_47277634	0.24	ENST00000296861.2	TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr2_+_101869262	0.23	ENST00000289382.3	CNOT11	CCR4-NOT transcription complex, subunit 11
chr4_-_84030996	0.23	ENST00000411416.2	PLAC8	placenta-specific 8
chr6_+_143381979	0.23	ENST00000367598.5 ENST00000447498.1 ENST00000357847.4 ENST00000344492.5 ENST00000367596.1 ENST00000494282.2 ENST00000275235.4	AIG1	androgen-induced 1
chr19_+_38397839	0.23	ENST00000222345.6	SIPA1L3	signal-induced proliferation-associated 1 like 3
chr1_+_42921761	0.23	ENST00000372562.1	PPCS	phosphopantothenoylcysteine synthetase
chr9_-_124976185	0.23	ENST00000464484.2	LHX6	LIM homeobox 6
chr5_+_141016508	0.23	ENST00000444782.1 ENST00000521367.1 ENST00000297164.3	RELL2	RELT-like 2
chr5_-_134369973	0.22	ENST00000265340.7	PITX1	paired-like homeodomain 1
chr7_-_150498426	0.22	ENST00000447204.2	TMEM176B	transmembrane protein 176B
chrX_+_131157609	0.22	ENST00000496850.1	MST4	Serine/threonine-protein kinase MST4
chr17_-_43502987	0.22	ENST00000376922.2	ARHGAP27	Rho GTPase activating protein 27
chr9_-_124976154	0.22	ENST00000482062.1	LHX6	LIM homeobox 6
chr19_+_39989535	0.22	ENST00000356433.5	DLL3	delta-like 3 (Drosophila)
chr16_+_3194211	0.22	ENST00000428155.1	CASP16	caspase 16, apoptosis-related cysteine peptidase (putative)
chrX_+_70316005	0.22	ENST00000374259.3	FOXO4	forkhead box O4
chr1_+_155179012	0.21	ENST00000609421.1	MTX1	metaxin 1
chr15_+_90319557	0.21	ENST00000341735.3	MESP2	mesoderm posterior 2 homolog (mouse)
chr14_+_24540046	0.21	ENST00000397016.2 ENST00000537691.1 ENST00000560356.1 ENST00000558450.1	CPNE6	copine VI (neuronal)
chr1_-_155006224	0.21	ENST00000368424.3	DCST2	DC-STAMP domain containing 2
chr1_+_107683436	0.21	ENST00000370068.1	NTNG1	netrin G1
chr10_-_8095412	0.21	ENST00000458727.1 ENST00000355358.1	RP11-379F12.3 GATA3-AS1	RP11-379F12.3 GATA3 antisense RNA 1
chr12_+_6493319	0.21	ENST00000536876.1	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr19_+_42301079	0.21	ENST00000596544.1	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3
chr19_+_42387228	0.21	ENST00000354532.3 ENST00000599846.1 ENST00000347545.4	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1
chr5_-_93077293	0.21	ENST00000510627.4	POU5F2	POU domain class 5, transcription factor 2
chr17_+_79761997	0.21	ENST00000400723.3 ENST00000570996.1	GCGR	glucagon receptor
chr1_+_29213584	0.20	ENST00000343067.4 ENST00000356093.2 ENST00000398863.2 ENST00000373800.3 ENST00000349460.4	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr16_-_66959429	0.20	ENST00000420652.1 ENST00000299759.6	RRAD	Ras-related associated with diabetes
chr1_+_107683644	0.20	ENST00000370067.1	NTNG1	netrin G1
chr12_-_15114492	0.20	ENST00000541546.1	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr5_+_61708582	0.20	ENST00000325324.6	IPO11	importin 11
chr3_-_48471454	0.20	ENST00000296440.6 ENST00000448774.2	PLXNB1	plexin B1
chr13_+_52158610	0.20	ENST00000298125.5	WDFY2	WD repeat and FYVE domain containing 2
chr1_-_6321035	0.20	ENST00000377893.2	GPR153	G protein-coupled receptor 153
chr3_-_52443799	0.20	ENST00000470173.1 ENST00000296288.5	BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr2_-_191399426	0.19	ENST00000409150.3	TMEM194B	transmembrane protein 194B
chr22_+_21987005	0.19	ENST00000607942.1 ENST00000425975.1 ENST00000292779.3	CCDC116	coiled-coil domain containing 116
chr1_+_155178481	0.19	ENST00000368376.3	MTX1	metaxin 1
chr13_-_25745857	0.19	ENST00000381853.3	AMER2	APC membrane recruitment protein 2
chr21_+_37692481	0.19	ENST00000400485.1	MORC3	MORC family CW-type zinc finger 3
chr6_-_34664612	0.19	ENST00000374023.3 ENST00000374026.3	C6orf106	chromosome 6 open reading frame 106
chrX_+_21392529	0.19	ENST00000425654.2 ENST00000543067.1	CNKSR2	connector enhancer of kinase suppressor of Ras 2
chr2_+_112812778	0.19	ENST00000283206.4	TMEM87B	transmembrane protein 87B
chr11_-_64512469	0.19	ENST00000377485.1	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr12_-_15114191	0.19	ENST00000541380.1	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr19_+_13229126	0.19	ENST00000292431.4	NACC1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr20_-_49639612	0.18	ENST00000396017.3 ENST00000433903.1	KCNG1	potassium voltage-gated channel, subfamily G, member 1
chr12_-_15114603	0.18	ENST00000228945.4	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr19_+_35630022	0.18	ENST00000589209.1	FXYD1	FXYD domain containing ion transport regulator 1
chr19_-_1650666	0.18	ENST00000588136.1	TCF3	transcription factor 3
chr12_-_95941987	0.18	ENST00000537435.2	USP44	ubiquitin specific peptidase 44
chr15_-_50647370	0.18	ENST00000558970.1 ENST00000396464.3 ENST00000560825.1	GABPB1	GA binding protein transcription factor, beta subunit 1
chr17_-_17399701	0.18	ENST00000225688.3 ENST00000579152.1	RASD1	RAS, dexamethasone-induced 1
chr4_+_78078304	0.18	ENST00000316355.5 ENST00000354403.5 ENST00000502280.1	CCNG2	cyclin G2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0060901	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.8	2.5	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.5	1.5	GO:0060166	olfactory pit development(GO:0060166)
0.3	0.9	GO:0070666	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.3	1.9	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.3	0.8	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2	0.7	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2	0.7	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.2	0.6	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.2	0.9	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.2	0.5	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.1	0.4	GO:0031133	regulation of axon diameter(GO:0031133)
0.1	0.6	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.5	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.6	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.4	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	1.0	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1	0.7	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1	0.3	GO:0060061	Spemann organizer formation(GO:0060061)
0.1	0.8	GO:0002934	desmosome organization(GO:0002934)
0.1	0.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.5	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	1.2	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.8	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.6	GO:0071461	cellular response to redox state(GO:0071461)
0.1	0.4	GO:0035106	operant conditioning(GO:0035106)
0.1	0.2	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.1	0.2	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.1	0.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	1.2	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.5	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.5	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.1	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.1	0.5	GO:0007386	compartment pattern specification(GO:0007386)
0.1	1.9	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.3	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.1	0.3	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.1	0.5	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	0.2	GO:0060066	negative regulation of mitotic cell cycle, embryonic(GO:0045976) oviduct development(GO:0060066) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1	1.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.4	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.2	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.3	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1	0.2	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1	0.2	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.8	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.3	GO:0010734	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.2	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0	0.2	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.2	GO:0098886	modification of dendritic spine(GO:0098886)
0.0	0.7	GO:0060019	radial glial cell differentiation(GO:0060019)
0.0	0.4	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0043686	co-translational protein modification(GO:0043686)
0.0	0.1	GO:0097187	dentinogenesis(GO:0097187)
0.0	0.3	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	1.0	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.1	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0	0.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.4	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.2	GO:1905176	metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0	0.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.0	0.5	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	1.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	1.7	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	1.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0015692	lead ion transport(GO:0015692)
0.0	0.7	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.9	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0	1.2	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:1904404	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0	0.1	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.0	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.5	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.1	GO:0033590	response to cobalamin(GO:0033590)
0.0	0.1	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0	0.1	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.0	0.1	GO:0035900	response to isolation stress(GO:0035900)
0.0	0.6	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0	1.0	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0	0.1	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
0.0	0.7	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.6	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
0.0	0.1	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0	0.4	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	0.4	GO:0014029	neural crest formation(GO:0014029)
0.0	0.3	GO:0035634	response to stilbenoid(GO:0035634)
0.0	0.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0	2.9	GO:0070268	cornification(GO:0070268)
0.0	0.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.3	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.3	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:1903276	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0	0.2	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.4	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.1	GO:0015942	formate metabolic process(GO:0015942)
0.0	1.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	1.6	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.1	GO:0072125	negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.0	GO:0003335	corneocyte development(GO:0003335)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	2.5	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0003344	pericardium morphogenesis(GO:0003344) midbrain morphogenesis(GO:1904693)
0.0	0.1	GO:0014063	regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.0	0.0	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.0	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.0	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.4	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.0	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.3	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.4	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0051255	spindle midzone assembly(GO:0051255)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.1	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.2	GO:0090520	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.3	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0060187	cell pole(GO:0060187)
0.2	0.9	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.2	1.5	GO:0044194	cytolytic granule(GO:0044194)
0.1	1.9	GO:0045179	apical cortex(GO:0045179)
0.1	0.3	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.3	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.6	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0044609	DBIRD complex(GO:0044609)
0.1	1.5	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.3	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	0.8	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	1.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	1.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	4.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.8	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.2	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0097444	spine apparatus(GO:0097444)
0.0	0.7	GO:0001533	cornified envelope(GO:0001533)
0.0	3.1	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.5	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.5	GO:0051233	spindle midzone(GO:0051233)
0.0	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	1.0	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.0	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.3	GO:0005905	clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3	1.0	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3	0.8	GO:0038131	neuregulin receptor activity(GO:0038131)
0.3	1.6	GO:0030348	syntaxin-3 binding(GO:0030348)
0.2	1.9	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2	1.5	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.2	0.5	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.2	0.8	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2	1.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.6	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.6	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	1.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.7	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	0.4	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1	0.4	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1	1.9	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	1.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	1.1	GO:0031014	troponin T binding(GO:0031014)
0.1	1.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	1.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	1.0	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.3	GO:0000822	inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.5	GO:0071253	connexin binding(GO:0071253)
0.1	0.3	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	0.4	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	2.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.8	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.1	0.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.2	GO:0015039	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	1.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.2	GO:0070404	NADH binding(GO:0070404)
0.0	0.5	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.5	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.4	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.2	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.1	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	1.9	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.9	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	2.2	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.5	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.4	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	2.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0031691	alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) platelet activating factor receptor binding(GO:0031859)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.4	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.2	GO:0005113	patched binding(GO:0005113)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.6	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.1	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	1.4	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	0.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	2.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.2	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.8	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.8	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.7	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.6	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.9	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors