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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for TP53

Z-value: 1.56

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
TP53
ENSG00000141510.11 TP53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_75908560.245.7e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_51504411 2.00 ENST00000593490.1
 KLK8
 kallikrein-related peptidase 8
chr1_-_153588334 1.94 ENST00000476873.1
 S100A14
 S100 calcium binding protein A14
chr18_-_28622774 1.65 ENST00000434452.1
 DSC3
 desmocollin 3
chr18_-_28622699 1.64 ENST00000360428.4
 DSC3
 desmocollin 3
chr6_+_36098262 1.49 ENST00000373761.6
ENST00000373766.5
 MAPK13
 mitogen-activated protein kinase 13
chr10_+_48255253 1.35 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
 ANXA8
AL591684.1
 annexin A8
Protein LOC100996760
chr15_+_40532058 1.31 ENST00000260404.4
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr10_+_47746929 1.29 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
 ANXA8L2
AL603965.1
 annexin A8-like 2
Protein LOC100996760
chr8_-_10588010 1.16 ENST00000304501.1
 SOX7
 SRY (sex determining region Y)-box 7
chr3_-_12800751 0.97 ENST00000435218.2
ENST00000435575.1
 TMEM40
 transmembrane protein 40
chr11_-_108464465 0.97 ENST00000525344.1
 EXPH5
 exophilin 5
chr1_-_209825674 0.94 ENST00000367030.3
ENST00000356082.4
 LAMB3
 laminin, beta 3
chr11_-_108464321 0.93 ENST00000265843.4
 EXPH5
 exophilin 5
chr6_+_36097992 0.83 ENST00000211287.4
 MAPK13
 mitogen-activated protein kinase 13
chr10_-_47173994 0.78 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
 ANXA8L1
LINC00842
 annexin A8-like 1
long intergenic non-protein coding RNA 842
chr16_+_57653989 0.78 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
 GPR56
 G protein-coupled receptor 56
chr16_+_57653854 0.77 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
 GPR56
 G protein-coupled receptor 56
chr13_+_37006421 0.71 ENST00000255465.4
 CCNA1
 cyclin A1
chr13_+_37006398 0.70 ENST00000418263.1
 CCNA1
 cyclin A1
chr9_-_135996537 0.68 ENST00000372050.3
ENST00000372047.3
 RALGDS
 ral guanine nucleotide dissociation stimulator
chr6_-_30712313 0.68 ENST00000376377.2
ENST00000259874.5
 IER3
 immediate early response 3
chr6_-_138428613 0.67 ENST00000421351.3
 PERP
 PERP, TP53 apoptosis effector
chr8_-_23082580 0.65 ENST00000221132.3
 TNFRSF10A
 tumor necrosis factor receptor superfamily, member 10a
chr11_+_1856034 0.63 ENST00000341958.3
 SYT8
 synaptotagmin VIII
chr12_+_44229846 0.60 ENST00000551577.1
ENST00000266534.3
 TMEM117
 transmembrane protein 117
chr12_-_126467906 0.58 ENST00000507313.1
ENST00000545784.1
 LINC00939
 long intergenic non-protein coding RNA 939
chr16_+_57406368 0.58 ENST00000006053.6
ENST00000563383.1
 CX3CL1
 chemokine (C-X3-C motif) ligand 1
chr1_+_13910479 0.56 ENST00000509009.1
 PDPN
 podoplanin
chr11_+_706595 0.55 ENST00000531348.1
ENST00000530636.1
 EPS8L2
 EPS8-like 2
chr11_+_1855645 0.51 ENST00000381968.3
ENST00000381978.3
 SYT8
 synaptotagmin VIII
chr11_-_44972476 0.51 ENST00000527685.1
ENST00000308212.5
 TP53I11
 tumor protein p53 inducible protein 11
chr1_+_13910757 0.50 ENST00000376061.4
ENST00000513143.1
 PDPN
 podoplanin
chr11_-_44972390 0.49 ENST00000395648.3
ENST00000531928.2
 TP53I11
 tumor protein p53 inducible protein 11
chrX_+_37545012 0.49 ENST00000378616.3
 XK
 X-linked Kx blood group (McLeod syndrome)
chr19_+_3136115 0.47 ENST00000262958.3
 GNA15
 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr1_-_201438282 0.45 ENST00000367311.3
ENST00000367309.1
 PHLDA3
 pleckstrin homology-like domain, family A, member 3
chr4_-_48908737 0.44 ENST00000381464.2
 OCIAD2
 OCIA domain containing 2
chr1_+_13910194 0.43 ENST00000376057.4
ENST00000510906.1
 PDPN
 podoplanin
chr4_+_103422471 0.41 ENST00000226574.4
ENST00000394820.4
 NFKB1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr8_-_22926526 0.39 ENST00000347739.3
ENST00000542226.1
 TNFRSF10B
 tumor necrosis factor receptor superfamily, member 10b
chr1_-_38412683 0.39 ENST00000373024.3
ENST00000373023.2
 INPP5B
 inositol polyphosphate-5-phosphatase, 75kDa
chr4_-_48908805 0.38 ENST00000273860.4
 OCIAD2
 OCIA domain containing 2
chr1_-_10532531 0.38 ENST00000377036.2
ENST00000377038.3
 DFFA
 DNA fragmentation factor, 45kDa, alpha polypeptide
chr4_-_48908822 0.37 ENST00000508632.1
 OCIAD2
 OCIA domain containing 2
chr22_+_38302285 0.36 ENST00000215957.6
 MICALL1
 MICAL-like 1
chr11_-_59383617 0.34 ENST00000263847.1
 OSBP
 oxysterol binding protein
chr2_-_75788038 0.33 ENST00000393913.3
ENST00000410113.1
 EVA1A
 eva-1 homolog A (C. elegans)
chr7_-_72439997 0.33 ENST00000285805.3
 TRIM74
 tripartite motif containing 74
chr8_-_22926623 0.33 ENST00000276431.4
 TNFRSF10B
 tumor necrosis factor receptor superfamily, member 10b
chr2_+_233734994 0.32 ENST00000331342.2
 C2orf82
 chromosome 2 open reading frame 82
chr9_+_139847347 0.32 ENST00000371632.3
 LCN12
 lipocalin 12
chr3_+_184279566 0.31 ENST00000330394.2
 EPHB3
 EPH receptor B3
chr2_-_26205340 0.30 ENST00000264712.3
 KIF3C
 kinesin family member 3C
chr9_+_138606400 0.30 ENST00000486577.2
 KCNT1
 potassium channel, subfamily T, member 1
chr1_+_11796126 0.29 ENST00000376637.3
 AGTRAP
 angiotensin II receptor-associated protein
chr1_+_11796177 0.28 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
 AGTRAP
 angiotensin II receptor-associated protein
chr4_-_153457197 0.28 ENST00000281708.4
 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr17_-_74528128 0.28 ENST00000590175.1
 CYGB
 cytoglobin
chr5_-_95297534 0.27 ENST00000513343.1
ENST00000431061.2
 ELL2
 elongation factor, RNA polymerase II, 2
chr6_+_116692102 0.26 ENST00000359564.2
 DSE
 dermatan sulfate epimerase
chr22_-_18257178 0.26 ENST00000342111.5
 BID
 BH3 interacting domain death agonist
chrX_+_99899180 0.26 ENST00000373004.3
 SRPX2
 sushi-repeat containing protein, X-linked 2
chr1_-_156051789 0.25 ENST00000532414.2
 MEX3A
 mex-3 RNA binding family member A
chr11_+_64059464 0.24 ENST00000394525.2
 KCNK4
 potassium channel, subfamily K, member 4
chr3_+_122785895 0.24 ENST00000316218.7
 PDIA5
 protein disulfide isomerase family A, member 5
chr3_-_184079382 0.24 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
 CLCN2
 chloride channel, voltage-sensitive 2
chr1_+_10057274 0.24 ENST00000294435.7
 RBP7
 retinol binding protein 7, cellular
chr1_+_116519112 0.24 ENST00000369503.4
 SLC22A15
 solute carrier family 22, member 15
chr6_+_4776580 0.23 ENST00000397588.3
 CDYL
 chromodomain protein, Y-like
chr14_+_97263641 0.23 ENST00000216639.3
 VRK1
 vaccinia related kinase 1
chr19_-_51530916 0.23 ENST00000594768.1
 KLK11
 kallikrein-related peptidase 11
chr20_+_42984330 0.23 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
 HNF4A
 hepatocyte nuclear factor 4, alpha
chr19_-_42746714 0.23 ENST00000222330.3
 GSK3A
 glycogen synthase kinase 3 alpha
chr9_-_138853156 0.22 ENST00000371756.3
 UBAC1
 UBA domain containing 1
chr6_+_24403144 0.21 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
 MRS2
 MRS2 magnesium transporter
chr11_+_100558384 0.21 ENST00000524892.2
ENST00000298815.8
 ARHGAP42
 Rho GTPase activating protein 42
chr6_-_101329157 0.21 ENST00000369143.2
 ASCC3
 activating signal cointegrator 1 complex subunit 3
chr11_+_64126614 0.21 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
 RPS6KA4
 ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr19_-_47735918 0.20 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
 BBC3
 BCL2 binding component 3
chr12_-_64784471 0.20 ENST00000333722.5
 C12orf56
 chromosome 12 open reading frame 56
chr1_-_1356719 0.19 ENST00000520296.1
 ANKRD65
 ankyrin repeat domain 65
chr17_+_74372662 0.19 ENST00000591651.1
ENST00000545180.1
 SPHK1
 sphingosine kinase 1
chr19_+_39687596 0.18 ENST00000339852.4
 NCCRP1
 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr1_-_205744574 0.18 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr4_+_41937131 0.17 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
 TMEM33
 transmembrane protein 33
chr3_+_184079492 0.17 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
chr4_-_187644930 0.17 ENST00000441802.2
 FAT1
 FAT atypical cadherin 1
chr19_+_56652556 0.17 ENST00000337080.3
 ZNF444
 zinc finger protein 444
chr2_+_169312350 0.17 ENST00000305747.6
 CERS6
 ceramide synthase 6
chr10_-_105212059 0.17 ENST00000260743.5
 CALHM2
 calcium homeostasis modulator 2
chr1_-_205744205 0.16 ENST00000446390.2
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr22_+_29279552 0.16 ENST00000544604.2
 ZNRF3
 zinc and ring finger 3
chr2_+_169312725 0.16 ENST00000392687.4
 CERS6
 ceramide synthase 6
chr11_-_3078616 0.15 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
 CARS
 cysteinyl-tRNA synthetase
chr13_-_48877795 0.15 ENST00000436963.1
ENST00000433480.2
 LINC00441
 long intergenic non-protein coding RNA 441
chr1_-_1356628 0.15 ENST00000442470.1
ENST00000537107.1
 ANKRD65
 ankyrin repeat domain 65
chr19_-_17014408 0.14 ENST00000594249.1
 CPAMD8
 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr12_+_124086632 0.14 ENST00000238146.4
ENST00000538744.1
 DDX55
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr8_-_109799793 0.14 ENST00000297459.3
 TMEM74
 transmembrane protein 74
chr1_+_25598989 0.14 ENST00000454452.2
 RHD
 Rh blood group, D antigen
chr10_-_105212141 0.14 ENST00000369788.3
 CALHM2
 calcium homeostasis modulator 2
chr11_-_44972418 0.13 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
 TP53I11
 tumor protein p53 inducible protein 11
chr7_-_56101826 0.13 ENST00000421626.1
 PSPH
 phosphoserine phosphatase
chr20_-_1373606 0.13 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
 FKBP1A
 FK506 binding protein 1A, 12kDa
chr11_+_36397528 0.13 ENST00000311599.5
ENST00000378867.3
 PRR5L
 proline rich 5 like
chr12_+_12966250 0.13 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
 DDX47
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr3_-_46037299 0.13 ENST00000296137.2
 FYCO1
 FYVE and coiled-coil domain containing 1
chr1_+_211432700 0.13 ENST00000452621.2
 RCOR3
 REST corepressor 3
chr1_-_25747283 0.12 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
 RHCE
 Rh blood group, CcEe antigens
chr11_-_3078838 0.12 ENST00000397111.5
 CARS
 cysteinyl-tRNA synthetase
chr11_+_119039414 0.12 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
 NLRX1
 NLR family member X1
chr17_-_61523622 0.12 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
 CYB561
 cytochrome b561
chr14_-_36990354 0.12 ENST00000518149.1
 NKX2-1
 NK2 homeobox 1
chr5_+_72861560 0.12 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
 UTP15
 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr19_+_56652686 0.12 ENST00000592949.1
 ZNF444
 zinc finger protein 444
chr3_+_23851928 0.12 ENST00000467766.1
ENST00000424381.1
 UBE2E1
 ubiquitin-conjugating enzyme E2E 1
chr4_-_159644507 0.11 ENST00000307720.3
 PPID
 peptidylprolyl isomerase D
chr22_-_18257249 0.11 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
 BID
 BH3 interacting domain death agonist
chr2_+_95691417 0.11 ENST00000309988.4
 MAL
 mal, T-cell differentiation protein
chr19_+_13229126 0.11 ENST00000292431.4
 NACC1
 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr9_-_95527079 0.11 ENST00000356884.6
ENST00000375512.3
 BICD2
 bicaudal D homolog 2 (Drosophila)
chr5_+_121647877 0.11 ENST00000514497.2
ENST00000261367.7
 SNCAIP
 synuclein, alpha interacting protein
chr11_+_33278811 0.11 ENST00000303296.4
ENST00000379016.3
 HIPK3
 homeodomain interacting protein kinase 3
chr11_-_47400062 0.11 ENST00000533030.1
 SPI1
 spleen focus forming virus (SFFV) proviral integration oncogene
chrX_-_48827976 0.11 ENST00000218176.3
 KCND1
 potassium voltage-gated channel, Shal-related subfamily, member 1
chr17_-_61523535 0.11 ENST00000584031.1
ENST00000392976.1
 CYB561
 cytochrome b561
chr2_+_95691445 0.11 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
 MAL
 mal, T-cell differentiation protein
chr19_-_42721819 0.11 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
 DEDD2
 death effector domain containing 2
chr22_+_29168652 0.11 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
 CCDC117
 coiled-coil domain containing 117
chr12_+_53894672 0.11 ENST00000266987.2
ENST00000456234.2
 TARBP2
 TAR (HIV-1) RNA binding protein 2
chr5_+_121647764 0.11 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
 SNCAIP
 synuclein, alpha interacting protein
chr19_-_6481776 0.11 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
 DENND1C
 DENN/MADD domain containing 1C
chr11_-_77122928 0.10 ENST00000528203.1
ENST00000528592.1
ENST00000528633.1
ENST00000529248.1
 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
chr1_-_26197744 0.10 ENST00000374296.3
 PAQR7
 progestin and adipoQ receptor family member VII
chr11_+_61717279 0.10 ENST00000378043.4
 BEST1
 bestrophin 1
chr19_+_42746927 0.10 ENST00000378108.1
 AC006486.1
 AC006486.1
chr19_-_55690758 0.10 ENST00000590851.1
 SYT5
 synaptotagmin V
chr1_+_26485511 0.10 ENST00000374268.3
 FAM110D
 family with sequence similarity 110, member D
chr14_-_64971288 0.10 ENST00000394715.1
 ZBTB25
 zinc finger and BTB domain containing 25
chr1_+_42846443 0.10 ENST00000410070.2
ENST00000431473.3
 RIMKLA
 ribosomal modification protein rimK-like family member A
chr12_+_53895364 0.10 ENST00000552817.1
ENST00000394357.2
 TARBP2
 TAR (HIV-1) RNA binding protein 2
chr1_+_243419306 0.10 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
 SDCCAG8
 serologically defined colon cancer antigen 8
chr19_-_52150053 0.10 ENST00000599649.1
ENST00000429354.3
ENST00000360844.6
ENST00000222107.4
 SIGLEC5
SIGLEC14
SIGLEC5
 SIGLEC5
sialic acid binding Ig-like lectin 14
sialic acid binding Ig-like lectin 5
chr17_+_18087553 0.10 ENST00000399138.4
 ALKBH5
 alkB, alkylation repair homolog 5 (E. coli)
chr13_+_31480328 0.10 ENST00000380482.4
 MEDAG
 mesenteric estrogen-dependent adipogenesis
chr14_-_64970494 0.10 ENST00000608382.1
 ZBTB25
 zinc finger and BTB domain containing 25
chr12_+_53895052 0.10 ENST00000552857.1
 TARBP2
 TAR (HIV-1) RNA binding protein 2
chr2_+_47168630 0.09 ENST00000263737.6
 TTC7A
 tetratricopeptide repeat domain 7A
chr1_-_202936394 0.09 ENST00000367249.4
 CYB5R1
 cytochrome b5 reductase 1
chr1_-_150738261 0.09 ENST00000448301.2
ENST00000368985.3
 CTSS
 cathepsin S
chr3_-_113465065 0.09 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
 NAA50
 N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr13_-_20735178 0.09 ENST00000241125.3
 GJA3
 gap junction protein, alpha 3, 46kDa
chr16_-_4303767 0.09 ENST00000573268.1
ENST00000573042.1
 RP11-95P2.1
 RP11-95P2.1
chr11_+_61717336 0.09 ENST00000378042.3
 BEST1
 bestrophin 1
chr2_+_85661918 0.09 ENST00000340326.2
 SH2D6
 SH2 domain containing 6
chr5_-_72861484 0.09 ENST00000296785.3
 ANKRA2
 ankyrin repeat, family A (RFXANK-like), 2
chr8_-_124253576 0.09 ENST00000276704.4
 C8orf76
 chromosome 8 open reading frame 76
chr6_-_114292449 0.09 ENST00000519065.1
 HDAC2
 histone deacetylase 2
chr11_-_129062093 0.08 ENST00000310343.9
 ARHGAP32
 Rho GTPase activating protein 32
chr2_-_242556900 0.08 ENST00000402545.1
ENST00000402136.1
 THAP4
 THAP domain containing 4
chr9_-_104160872 0.08 ENST00000539624.1
ENST00000374865.4
 MRPL50
 mitochondrial ribosomal protein L50
chr5_+_121647386 0.08 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
 SNCAIP
 synuclein, alpha interacting protein
chr3_+_196466710 0.08 ENST00000327134.3
 PAK2
 p21 protein (Cdc42/Rac)-activated kinase 2
chr19_+_2785458 0.08 ENST00000307741.6
ENST00000585338.1
 THOP1
 thimet oligopeptidase 1
chr17_+_18128896 0.08 ENST00000316843.4
 LLGL1
 lethal giant larvae homolog 1 (Drosophila)
chr1_-_2458026 0.08 ENST00000435556.3
ENST00000378466.3
 PANK4
 pantothenate kinase 4
chr12_-_113772835 0.08 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
 SLC8B1
 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr6_-_114292284 0.08 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
 HDAC2
 histone deacetylase 2
chr11_+_64073699 0.08 ENST00000405666.1
ENST00000468670.1
 ESRRA
 estrogen-related receptor alpha
chr19_-_1605424 0.08 ENST00000589880.1
ENST00000585671.1
ENST00000591899.3
 UQCR11
 ubiquinol-cytochrome c reductase, complex III subunit XI
chr10_-_126847276 0.08 ENST00000531469.1
 CTBP2
 C-terminal binding protein 2
chr3_-_100120223 0.08 ENST00000284320.5
 TOMM70A
 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr20_-_23618582 0.07 ENST00000398411.1
ENST00000376925.3
 CST3
 cystatin C
chr14_-_102553371 0.07 ENST00000553585.1
ENST00000216281.8
 HSP90AA1
 heat shock protein 90kDa alpha (cytosolic), class A member 1
chr19_-_5567842 0.07 ENST00000587632.1
 TINCR
 tissue differentiation-inducing non-protein coding RNA
chr6_-_101329191 0.07 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
 ASCC3
 activating signal cointegrator 1 complex subunit 3
chr1_+_27153173 0.07 ENST00000374142.4
 ZDHHC18
 zinc finger, DHHC-type containing 18
chr9_-_116037840 0.06 ENST00000374206.3
 CDC26
 cell division cycle 26
chr3_-_52479043 0.06 ENST00000231721.2
ENST00000475739.1
 SEMA3G
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chrX_-_153285395 0.06 ENST00000369980.3
 IRAK1
 interleukin-1 receptor-associated kinase 1
chr20_-_61002584 0.06 ENST00000252998.1
 RBBP8NL
 RBBP8 N-terminal like
chr8_-_12051576 0.06 ENST00000524571.2
ENST00000533852.2
ENST00000533513.1
ENST00000448228.2
ENST00000534520.1
ENST00000321602.8
 FAM86B1
 family with sequence similarity 86, member B1
chr5_-_131892501 0.06 ENST00000450655.1
 IL5
 interleukin 5 (colony-stimulating factor, eosinophil)
chr22_+_19705928 0.06 ENST00000383045.3
ENST00000438754.2
 SEPT5
 septin 5
chr11_-_77123065 0.06 ENST00000530617.1
 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
chr19_+_827823 0.06 ENST00000233997.2
 AZU1
 azurocidin 1
chr19_+_51293672 0.06 ENST00000270593.1
ENST00000270594.3
 ACPT
 acid phosphatase, testicular
chr1_-_169396666 0.06 ENST00000456107.1
ENST00000367805.3
 CCDC181
 coiled-coil domain containing 181
chr16_-_58231782 0.06 ENST00000565188.1
ENST00000262506.3
 CSNK2A2
 casein kinase 2, alpha prime polypeptide
chr2_+_47168313 0.06 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
 TTC7A
 tetratricopeptide repeat domain 7A
chr17_-_14140166 0.06 ENST00000420162.2
ENST00000431716.2
 CDRT15
 CMT1A duplicated region transcript 15
chr1_+_54411715 0.06 ENST00000371370.3
ENST00000371368.1
 LRRC42
 leucine rich repeat containing 42
chr19_+_13988061 0.05 ENST00000339133.5
ENST00000397555.2
 NANOS3
 nanos homolog 3 (Drosophila)
chr17_-_5095126 0.05 ENST00000576772.1
ENST00000575779.1
 ZNF594
 zinc finger protein 594
chr1_+_25598872 0.05 ENST00000328664.4
 RHD
 Rh blood group, D antigen
chr11_+_60699222 0.05 ENST00000536409.1
 TMEM132A
 transmembrane protein 132A
chr1_+_44115814 0.05 ENST00000372396.3
 KDM4A
 lysine (K)-specific demethylase 4A
chr3_+_149530469 0.05 ENST00000392894.3
ENST00000344229.3
 RNF13
 ring finger protein 13
chr5_+_121647924 0.05 ENST00000414317.2
 SNCAIP
 synuclein, alpha interacting protein
chr12_-_14721283 0.05 ENST00000240617.5
 PLBD1
 phospholipase B domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3 1.3 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.2 2.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 0.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.2 0.5 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.4 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.3 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 1.9 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.4 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 0.4 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.2 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.5 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 1.9 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.7 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 1.4 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.4 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 3.3 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 2.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 1.2 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0045348 positive regulation of chemokine biosynthetic process(GO:0045080) positive regulation of MHC class II biosynthetic process(GO:0045348) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 1.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 1.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 4.0 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0045569 TRAIL binding(GO:0045569)
0.1 1.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.3 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 2.0 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 2.5 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0038023 steroid hormone receptor activity(GO:0003707) signaling receptor activity(GO:0038023)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis