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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ZIC3_ZIC4

Z-value: 0.41

Motif logo

Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ENSG00000156925.7 ZIC3
ENSG00000174963.13 ZIC4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC4hg19_v2_chr3_-_147124547_1471246470.462.5e-01Click!
ZIC3hg19_v2_chrX_+_136648297_1366483190.196.5e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_75699149 1.31 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr5_+_75699040 1.21 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr17_-_43045439 0.59 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chrX_+_51927919 0.54 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr12_+_56075330 0.42 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr14_-_30396802 0.31 ENST00000415220.2
PRKD1
protein kinase D1
chr2_-_99552620 0.31 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr2_+_128180842 0.31 ENST00000402125.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr7_+_149571045 0.29 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr10_+_13142075 0.28 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr10_+_13142225 0.28 ENST00000378747.3
OPTN
optineurin
chr2_+_8822113 0.28 ENST00000396290.1
ENST00000331129.3
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr21_+_37507210 0.25 ENST00000290354.5
CBR3
carbonyl reductase 3
chr16_+_4364762 0.25 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr4_+_52917451 0.23 ENST00000295213.4
ENST00000419395.2
SPATA18
spermatogenesis associated 18
chr16_+_30996502 0.23 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr5_+_126626498 0.23 ENST00000503335.2
ENST00000508365.1
ENST00000418761.2
ENST00000274473.6
MEGF10
multiple EGF-like-domains 10
chr3_+_54156570 0.22 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_+_38599693 0.22 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chr5_-_126366500 0.22 ENST00000308660.5
MARCH3
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
chr3_+_54156664 0.22 ENST00000474759.1
ENST00000288197.5
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr3_+_12330560 0.22 ENST00000397026.2
PPARG
peroxisome proliferator-activated receptor gamma
chr14_+_100848311 0.22 ENST00000542471.2
WDR25
WD repeat domain 25
chr11_-_2906979 0.21 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr19_-_58609570 0.21 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18
zinc finger and SCAN domain containing 18
chr10_+_13141441 0.21 ENST00000263036.5
OPTN
optineurin
chr3_-_112356944 0.21 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr1_+_38273818 0.20 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr1_+_38273988 0.20 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr20_+_34203794 0.20 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr17_+_78194205 0.19 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr10_+_13141585 0.19 ENST00000378764.2
OPTN
optineurin
chr2_-_45236540 0.19 ENST00000303077.6
SIX2
SIX homeobox 2
chr4_+_74718906 0.18 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr1_+_215256467 0.18 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chr2_+_23608064 0.18 ENST00000486442.1
KLHL29
kelch-like family member 29
chr11_+_64781575 0.17 ENST00000246747.4
ENST00000529384.1
ARL2
ADP-ribosylation factor-like 2
chr19_-_40791211 0.17 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr9_+_4490394 0.17 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_+_20646824 0.17 ENST00000272233.4
RHOB
ras homolog family member B
chr12_+_51785057 0.17 ENST00000535225.2
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr14_+_24630465 0.17 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr19_+_45409011 0.16 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr16_+_2039946 0.16 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr11_+_64781657 0.15 ENST00000533729.1
ARL2
ADP-ribosylation factor-like 2
chr13_+_35516390 0.15 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr17_-_39191107 0.15 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr5_-_151304337 0.15 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
GLRA1
glycine receptor, alpha 1
chr19_+_49617581 0.14 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr1_+_43148625 0.14 ENST00000436427.1
YBX1
Y box binding protein 1
chr5_-_14871866 0.14 ENST00000284268.6
ANKH
ANKH inorganic pyrophosphate transport regulator
chr5_+_140753444 0.14 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr11_-_67272794 0.14 ENST00000436757.2
ENST00000356404.3
PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr19_-_51587502 0.14 ENST00000156499.2
ENST00000391802.1
KLK14
kallikrein-related peptidase 14
chr1_+_52521797 0.13 ENST00000313334.8
BTF3L4
basic transcription factor 3-like 4
chr17_-_39183452 0.13 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr5_-_111091948 0.13 ENST00000447165.2
NREP
neuronal regeneration related protein
chr10_-_79397479 0.13 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_+_38869298 0.13 ENST00000510213.1
ENST00000515037.1
FAM114A1
family with sequence similarity 114, member A1
chr1_+_201617264 0.13 ENST00000367296.4
NAV1
neuron navigator 1
chr17_-_78194147 0.13 ENST00000534910.1
ENST00000326317.6
SGSH
N-sulfoglucosamine sulfohydrolase
chr6_-_85473156 0.13 ENST00000606784.1
ENST00000606325.1
TBX18
T-box 18
chr1_+_201617450 0.13 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1
neuron navigator 1
chr19_+_49617609 0.13 ENST00000221459.2
ENST00000486217.2
LIN7B
lin-7 homolog B (C. elegans)
chrX_+_153686614 0.13 ENST00000369682.3
PLXNA3
plexin A3
chr1_+_33352036 0.12 ENST00000373467.3
HPCA
hippocalcin
chr1_+_52521957 0.12 ENST00000472944.2
ENST00000484036.1
BTF3L4
basic transcription factor 3-like 4
chr11_-_65150103 0.12 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr6_+_89791507 0.12 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr2_+_105050794 0.12 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr11_-_74109422 0.12 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chrX_-_34675391 0.11 ENST00000275954.3
TMEM47
transmembrane protein 47
chr17_+_39394250 0.11 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr7_+_106809406 0.11 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr22_-_41636929 0.11 ENST00000216241.9
CHADL
chondroadherin-like
chr10_+_35416223 0.11 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr19_+_13135790 0.11 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_56150184 0.11 ENST00000394554.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr17_-_7531121 0.10 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr2_-_10220538 0.10 ENST00000381813.4
CYS1
cystin 1
chr2_+_48757278 0.10 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr1_+_52521928 0.10 ENST00000489308.2
BTF3L4
basic transcription factor 3-like 4
chr6_+_33168637 0.10 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr6_+_33168597 0.10 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr2_+_37571845 0.10 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr4_+_38869410 0.09 ENST00000358869.2
FAM114A1
family with sequence similarity 114, member A1
chr8_-_27462822 0.09 ENST00000522098.1
CLU
clusterin
chr19_+_45251804 0.09 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr21_+_38445539 0.09 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr2_-_201374781 0.09 ENST00000359878.3
ENST00000409157.1
KCTD18
potassium channel tetramerization domain containing 18
chr3_+_11196206 0.09 ENST00000431010.2
HRH1
histamine receptor H1
chr3_-_9811595 0.09 ENST00000256460.3
CAMK1
calcium/calmodulin-dependent protein kinase I
chr20_+_49411523 0.09 ENST00000371608.2
BCAS4
breast carcinoma amplified sequence 4
chr5_+_140718396 0.09 ENST00000394576.2
PCDHGA2
protocadherin gamma subfamily A, 2
chr2_+_37571717 0.09 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr20_-_31172598 0.09 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr17_+_38219063 0.09 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA
thyroid hormone receptor, alpha
chr10_-_79397202 0.09 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_131563501 0.09 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr17_+_260097 0.09 ENST00000360127.6
ENST00000571106.1
ENST00000491373.1
C17orf97
chromosome 17 open reading frame 97
chr14_-_23822080 0.09 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr5_-_76383133 0.09 ENST00000255198.2
ZBED3
zinc finger, BED-type containing 3
chr1_-_43232649 0.08 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr19_-_50143452 0.08 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr2_+_101436564 0.08 ENST00000335681.5
NPAS2
neuronal PAS domain protein 2
chr5_-_176923803 0.08 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr1_-_154928562 0.08 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr5_+_139027877 0.08 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr1_+_43148059 0.08 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr5_-_176923846 0.08 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr17_-_73178599 0.08 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr1_+_156024552 0.08 ENST00000368304.5
ENST00000368302.3
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr12_+_108523489 0.08 ENST00000261400.3
WSCD2
WSC domain containing 2
chr10_-_88854518 0.08 ENST00000277865.4
GLUD1
glutamate dehydrogenase 1
chr4_+_81951957 0.08 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr19_+_54926601 0.08 ENST00000301194.4
TTYH1
tweety family member 1
chr19_+_33685490 0.08 ENST00000253193.7
LRP3
low density lipoprotein receptor-related protein 3
chr4_+_115519577 0.08 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr12_+_108523133 0.07 ENST00000547525.1
WSCD2
WSC domain containing 2
chr5_-_178157700 0.07 ENST00000335815.2
ZNF354A
zinc finger protein 354A
chr16_+_2198604 0.07 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr13_-_52378231 0.07 ENST00000280056.2
ENST00000444610.2
DHRS12
dehydrogenase/reductase (SDR family) member 12
chr17_-_19619917 0.07 ENST00000325411.5
ENST00000350657.5
ENST00000433844.2
SLC47A2
solute carrier family 47 (multidrug and toxin extrusion), member 2
chr17_-_1083078 0.07 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chrX_+_102631844 0.07 ENST00000372634.1
ENST00000299872.7
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr19_-_48752812 0.07 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr10_+_85954377 0.07 ENST00000332904.3
ENST00000372117.3
CDHR1
cadherin-related family member 1
chr20_+_3869423 0.07 ENST00000497424.1
PANK2
pantothenate kinase 2
chr11_-_2160180 0.07 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_-_48753104 0.07 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr11_-_73694346 0.07 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr3_+_195413160 0.07 ENST00000599448.1
LINC00969
long intergenic non-protein coding RNA 969
chr2_+_238768187 0.07 ENST00000254661.4
ENST00000409726.1
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr1_+_156024525 0.07 ENST00000368305.4
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr9_-_98279241 0.07 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr11_-_2158507 0.07 ENST00000381392.1
ENST00000381395.1
ENST00000418738.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_+_134145735 0.07 ENST00000368613.4
LRRC27
leucine rich repeat containing 27
chr1_+_43232913 0.07 ENST00000372525.5
ENST00000536543.1
C1orf50
chromosome 1 open reading frame 50
chr10_+_28966271 0.07 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr1_+_6845578 0.07 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr20_-_56286479 0.07 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_27850141 0.07 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr13_+_27131798 0.07 ENST00000361042.4
WASF3
WAS protein family, member 3
chr1_-_146644036 0.07 ENST00000425272.2
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr10_+_45455207 0.07 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
RASSF4
Ras association (RalGDS/AF-6) domain family member 4
chr12_-_57824739 0.07 ENST00000347140.3
ENST00000402412.1
R3HDM2
R3H domain containing 2
chr22_-_47134077 0.07 ENST00000541677.1
ENST00000216264.8
CERK
ceramide kinase
chrX_+_102631248 0.07 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_-_212873267 0.07 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr5_-_176924562 0.07 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7
PDZ and LIM domain 7 (enigma)
chr21_-_45196326 0.07 ENST00000291568.5
CSTB
cystatin B (stefin B)
chr20_+_3870024 0.06 ENST00000610179.1
PANK2
pantothenate kinase 2
chr16_-_1993260 0.06 ENST00000361871.3
MSRB1
methionine sulfoxide reductase B1
chr19_+_54926621 0.06 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1
tweety family member 1
chr7_+_37888199 0.06 ENST00000199447.4
ENST00000455500.1
NME8
NME/NM23 family member 8
chr11_-_67275542 0.06 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr17_-_42276574 0.06 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr9_-_130742792 0.06 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr11_-_32457075 0.06 ENST00000448076.3
WT1
Wilms tumor 1
chr14_+_105781048 0.06 ENST00000458164.2
ENST00000447393.1
PACS2
phosphofurin acidic cluster sorting protein 2
chr17_+_45000483 0.06 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
GOSR2
golgi SNAP receptor complex member 2
chr6_-_38607673 0.06 ENST00000481247.1
BTBD9
BTB (POZ) domain containing 9
chr7_+_37888555 0.06 ENST00000444718.1
ENST00000440017.1
NME8
NME/NM23 family member 8
chr13_-_99404875 0.06 ENST00000376503.5
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
chr2_-_106015527 0.06 ENST00000344213.4
ENST00000358129.4
FHL2
four and a half LIM domains 2
chr1_+_85527987 0.06 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr19_-_18717627 0.06 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr5_+_76506706 0.06 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr12_-_59314246 0.06 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr3_-_17783990 0.06 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5
TBC1 domain family, member 5
chr19_+_37096194 0.06 ENST00000460670.1
ENST00000292928.2
ENST00000439428.1
ZNF382
zinc finger protein 382
chr1_-_182641037 0.06 ENST00000483095.2
RGS8
regulator of G-protein signaling 8
chr1_-_182640988 0.06 ENST00000367556.1
RGS8
regulator of G-protein signaling 8
chr12_-_121734489 0.06 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr16_-_18470696 0.06 ENST00000427999.2
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr16_-_31085514 0.06 ENST00000300849.4
ZNF668
zinc finger protein 668
chr17_-_73179046 0.06 ENST00000314523.7
ENST00000420826.2
SUMO2
small ubiquitin-like modifier 2
chr15_-_90294523 0.05 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr5_+_132202252 0.05 ENST00000378670.3
ENST00000378667.1
ENST00000378665.1
UQCRQ
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr22_-_19165917 0.05 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr3_+_50712672 0.05 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr1_+_218519577 0.05 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr20_-_3154162 0.05 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr19_+_13906250 0.05 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr21_+_45285050 0.05 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr16_-_8962853 0.05 ENST00000565287.1
ENST00000311052.5
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr19_-_53193731 0.05 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
ZNF83
zinc finger protein 83
chr1_+_114471809 0.05 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr3_-_99833333 0.05 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr22_+_23134974 0.05 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr11_-_119211525 0.05 ENST00000528368.1
C1QTNF5
C1q and tumor necrosis factor related protein 5
chr12_+_111471828 0.05 ENST00000261726.6
CUX2
cut-like homeobox 2
chr17_-_15903002 0.05 ENST00000399277.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr7_+_66205712 0.05 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
KCTD7
RABGEF1
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr2_+_109150850 0.05 ENST00000544547.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_-_31381528 0.05 ENST00000339394.6
SDC3
syndecan 3
chr15_-_66790146 0.05 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr13_+_27131887 0.05 ENST00000335327.5
WASF3
WAS protein family, member 3
chr4_-_15656923 0.05 ENST00000382358.4
ENST00000412094.2
ENST00000341285.3
FBXL5
F-box and leucine-rich repeat protein 5
chr17_+_39261584 0.05 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0061743 motor learning(GO:0061743)
0.1 2.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.3 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.2 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.1 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.0 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.1 GO:0003129 heart induction(GO:0003129) regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.2 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.0 GO:0097212 cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0044301 climbing fiber(GO:0044301)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 2.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.0 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion