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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ZKSCAN1

Z-value: 0.29

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Transcription factors associated with ZKSCAN1

Gene Symbol Gene ID Gene Info
ZKSCAN1
ENSG00000106261.12 ZKSCAN1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg19_v2_chr7_+_99613195_99613206-0.265.3e-01Click!

Activity profile of ZKSCAN1 motif

Sorted Z-values of ZKSCAN1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_135394840 0.37 ENST00000503087.1
 TGFBI
 transforming growth factor, beta-induced, 68kDa
chr11_-_118134997 0.30 ENST00000278937.2
 MPZL2
 myelin protein zero-like 2
chr21_+_46117087 0.26 ENST00000400365.3
 KRTAP10-12
 keratin associated protein 10-12
chr1_+_65613340 0.23 ENST00000546702.1
 AK4
 adenylate kinase 4
chr1_+_65613217 0.21 ENST00000545314.1
 AK4
 adenylate kinase 4
chr19_-_38916839 0.20 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
 RASGRP4
 RAS guanyl releasing protein 4
chr19_-_38916822 0.20 ENST00000586305.1
 RASGRP4
 RAS guanyl releasing protein 4
chr20_+_44098346 0.15 ENST00000372676.3
 WFDC2
 WAP four-disulfide core domain 2
chr17_-_37323318 0.15 ENST00000444555.1
 ARL5C
 ADP-ribosylation factor-like 5C
chr11_-_58343319 0.14 ENST00000395074.2
 LPXN
 leupaxin
chrX_-_130423200 0.13 ENST00000361420.3
 IGSF1
 immunoglobulin superfamily, member 1
chr19_+_39138320 0.13 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
 ACTN4
 actinin, alpha 4
chrX_-_130423386 0.13 ENST00000370903.3
 IGSF1
 immunoglobulin superfamily, member 1
chr12_+_4385230 0.13 ENST00000536537.1
 CCND2
 cyclin D2
chr1_+_11333245 0.13 ENST00000376810.5
 UBIAD1
 UbiA prenyltransferase domain containing 1
chr15_+_75494214 0.13 ENST00000394987.4
 C15orf39
 chromosome 15 open reading frame 39
chr19_-_55660561 0.12 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
 TNNT1
 troponin T type 1 (skeletal, slow)
chr11_-_568369 0.12 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
 MIR210HG
 MIR210 host gene (non-protein coding)
chr11_+_33563821 0.11 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
 KIAA1549L
 KIAA1549-like
chr7_-_72439997 0.11 ENST00000285805.3
 TRIM74
 tripartite motif containing 74
chr1_-_177134024 0.10 ENST00000367654.3
 ASTN1
 astrotactin 1
chr19_+_39138271 0.10 ENST00000252699.2
 ACTN4
 actinin, alpha 4
chr15_-_49103235 0.10 ENST00000380950.2
 CEP152
 centrosomal protein 152kDa
chr7_+_75024903 0.10 ENST00000323819.3
ENST00000430211.1
 TRIM73
 tripartite motif containing 73
chr12_+_13197218 0.09 ENST00000197268.8
 KIAA1467
 KIAA1467
chr22_+_33197683 0.09 ENST00000266085.6
 TIMP3
 TIMP metallopeptidase inhibitor 3
chr20_-_56265680 0.09 ENST00000414037.1
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr10_+_102222798 0.09 ENST00000343737.5
 WNT8B
 wingless-type MMTV integration site family, member 8B
chr6_+_36922209 0.09 ENST00000373674.3
 PI16
 peptidase inhibitor 16
chr2_+_113931513 0.08 ENST00000245796.6
ENST00000441564.3
 PSD4
 pleckstrin and Sec7 domain containing 4
chr6_+_151815143 0.08 ENST00000239374.7
ENST00000367290.5
 CCDC170
 coiled-coil domain containing 170
chr15_-_49103184 0.08 ENST00000399334.3
ENST00000325747.5
 CEP152
 centrosomal protein 152kDa
chr9_-_112260531 0.08 ENST00000374541.2
ENST00000262539.3
 PTPN3
 protein tyrosine phosphatase, non-receptor type 3
chr1_+_45140360 0.07 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
 C1orf228
 chromosome 1 open reading frame 228
chrX_-_130423240 0.07 ENST00000370910.1
ENST00000370901.4
 IGSF1
 immunoglobulin superfamily, member 1
chr12_+_52400719 0.07 ENST00000293662.4
 GRASP
 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr17_+_26684604 0.07 ENST00000292114.3
ENST00000509083.1
 TMEM199
 transmembrane protein 199
chr12_-_123450986 0.07 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
 ABCB9
 ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_+_209859510 0.07 ENST00000367028.2
ENST00000261465.1
 HSD11B1
 hydroxysteroid (11-beta) dehydrogenase 1
chr20_+_43343476 0.07 ENST00000372868.2
 WISP2
 WNT1 inducible signaling pathway protein 2
chr6_+_35265586 0.06 ENST00000542066.1
ENST00000316637.5
 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
chr9_-_114090713 0.06 ENST00000302681.1
ENST00000374428.1
 OR2K2
 olfactory receptor, family 2, subfamily K, member 2
chr13_-_29069232 0.06 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
 FLT1
 fms-related tyrosine kinase 1
chr1_+_16083154 0.06 ENST00000375771.1
 FBLIM1
 filamin binding LIM protein 1
chr1_+_236958554 0.06 ENST00000366577.5
ENST00000418145.2
 MTR
 5-methyltetrahydrofolate-homocysteine methyltransferase
chr20_+_43343517 0.06 ENST00000372865.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr8_-_131028869 0.06 ENST00000518283.1
ENST00000519110.1
 FAM49B
 family with sequence similarity 49, member B
chr4_+_41540160 0.06 ENST00000503057.1
ENST00000511496.1
 LIMCH1
 LIM and calponin homology domains 1
chr10_+_106113515 0.06 ENST00000369704.3
ENST00000312902.5
 CCDC147
 coiled-coil domain containing 147
chr6_-_44281043 0.05 ENST00000244571.4
 AARS2
 alanyl-tRNA synthetase 2, mitochondrial
chr7_+_72742178 0.05 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
 FKBP6
 FK506 binding protein 6, 36kDa
chr19_+_3178736 0.05 ENST00000246115.3
 S1PR4
 sphingosine-1-phosphate receptor 4
chr17_-_46716647 0.05 ENST00000608940.1
 RP11-357H14.17
 RP11-357H14.17
chr17_+_27071002 0.05 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
 TRAF4
 TNF receptor-associated factor 4
chr9_-_139357413 0.05 ENST00000277537.6
 SEC16A
 SEC16 homolog A (S. cerevisiae)
chr20_+_44098385 0.05 ENST00000217425.5
ENST00000339946.3
 WFDC2
 WAP four-disulfide core domain 2
chr19_+_13135731 0.05 ENST00000587260.1
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr2_+_71127699 0.05 ENST00000234392.2
 VAX2
 ventral anterior homeobox 2
chr12_-_49319265 0.05 ENST00000552878.1
ENST00000453172.2
 FKBP11
 FK506 binding protein 11, 19 kDa
chr16_-_19729502 0.04 ENST00000219837.7
 KNOP1
 lysine-rich nucleolar protein 1
chr16_-_838329 0.04 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
 RPUSD1
 RNA pseudouridylate synthase domain containing 1
chr16_+_56899114 0.04 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
 SLC12A3
 solute carrier family 12 (sodium/chloride transporter), member 3
chr7_+_72742162 0.04 ENST00000431982.2
 FKBP6
 FK506 binding protein 6, 36kDa
chr14_+_103851712 0.04 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
 MARK3
 MAP/microtubule affinity-regulating kinase 3
chr19_+_51630287 0.04 ENST00000599948.1
 SIGLEC9
 sialic acid binding Ig-like lectin 9
chr17_+_18163848 0.04 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
 MIEF2
 mitochondrial elongation factor 2
chr3_-_71834318 0.04 ENST00000353065.3
 PROK2
 prokineticin 2
chr19_-_19051993 0.04 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
 HOMER3
 homer homolog 3 (Drosophila)
chr1_+_32083301 0.04 ENST00000403528.2
 HCRTR1
 hypocretin (orexin) receptor 1
chr3_+_52813932 0.04 ENST00000537050.1
 ITIH1
 inter-alpha-trypsin inhibitor heavy chain 1
chr15_+_75498739 0.04 ENST00000565074.1
 C15orf39
 chromosome 15 open reading frame 39
chr7_+_103969104 0.04 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
 LHFPL3
 lipoma HMGIC fusion partner-like 3
chr16_+_67562702 0.04 ENST00000379312.3
ENST00000042381.4
ENST00000540839.3
 FAM65A
 family with sequence similarity 65, member A
chr3_+_63898275 0.04 ENST00000538065.1
 ATXN7
 ataxin 7
chr1_+_16348366 0.04 ENST00000375692.1
ENST00000420078.1
 CLCNKA
 chloride channel, voltage-sensitive Ka
chr17_+_26800648 0.04 ENST00000545060.1
 SLC13A2
 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr19_+_13051206 0.03 ENST00000586760.1
 CALR
 calreticulin
chr22_-_37640277 0.03 ENST00000401529.3
ENST00000249071.6
 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_19125252 0.03 ENST00000566735.1
ENST00000381440.3
 ITPRIPL2
 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr17_+_26800756 0.03 ENST00000537681.1
 SLC13A2
 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr14_+_63671577 0.03 ENST00000555125.1
 RHOJ
 ras homolog family member J
chr11_+_72975578 0.03 ENST00000393592.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_72975524 0.03 ENST00000540342.1
ENST00000542092.1
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr19_+_18794470 0.03 ENST00000321949.8
ENST00000338797.6
 CRTC1
 CREB regulated transcription coactivator 1
chr19_+_16830774 0.03 ENST00000524140.2
 NWD1
 NACHT and WD repeat domain containing 1
chr1_+_226411319 0.03 ENST00000542034.1
ENST00000366810.5
 MIXL1
 Mix paired-like homeobox
chr1_+_113009163 0.03 ENST00000256640.5
 WNT2B
 wingless-type MMTV integration site family, member 2B
chr22_+_30805086 0.03 ENST00000439838.1
ENST00000439023.3
 RP4-539M6.19
 Uncharacterized protein
chrX_-_15402498 0.03 ENST00000297904.3
 FIGF
 c-fos induced growth factor (vascular endothelial growth factor D)
chr7_-_72742085 0.03 ENST00000333149.2
 TRIM50
 tripartite motif containing 50
chr2_+_27071045 0.03 ENST00000401478.1
 DPYSL5
 dihydropyrimidinase-like 5
chr4_+_39460689 0.03 ENST00000381846.1
 LIAS
 lipoic acid synthetase
chr11_+_72975559 0.03 ENST00000349767.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_157099036 0.03 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
 ARID1B
 AT rich interactive domain 1B (SWI1-like)
chr6_-_30640811 0.03 ENST00000376442.3
 DHX16
 DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr11_+_32112431 0.03 ENST00000054950.3
 RCN1
 reticulocalbin 1, EF-hand calcium binding domain
chr10_-_88281494 0.02 ENST00000298767.5
 WAPAL
 wings apart-like homolog (Drosophila)
chr19_-_15918936 0.02 ENST00000334920.2
 OR10H1
 olfactory receptor, family 10, subfamily H, member 1
chr2_+_27070964 0.02 ENST00000288699.6
 DPYSL5
 dihydropyrimidinase-like 5
chr1_+_40997233 0.02 ENST00000372699.3
ENST00000372697.3
ENST00000372696.3
 ZNF684
 zinc finger protein 684
chr1_+_16348497 0.02 ENST00000439316.2
 CLCNKA
 chloride channel, voltage-sensitive Ka
chr4_+_39460659 0.02 ENST00000513731.1
 LIAS
 lipoic acid synthetase
chr21_+_18811205 0.02 ENST00000440664.1
 C21orf37
 chromosome 21 open reading frame 37
chr11_+_46366918 0.02 ENST00000528615.1
ENST00000395574.3
 DGKZ
 diacylglycerol kinase, zeta
chr11_-_61197187 0.02 ENST00000449811.1
ENST00000413232.1
ENST00000340437.4
ENST00000539952.1
ENST00000544585.1
ENST00000450000.1
 CPSF7
 cleavage and polyadenylation specific factor 7, 59kDa
chr22_+_29702572 0.02 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
 GAS2L1
 growth arrest-specific 2 like 1
chr9_+_103189536 0.02 ENST00000374885.1
 MSANTD3
 Myb/SANT-like DNA-binding domain containing 3
chr12_-_112037306 0.02 ENST00000535949.1
ENST00000542287.2
ENST00000377617.3
ENST00000550104.1
 ATXN2
 ataxin 2
chr1_+_27648648 0.02 ENST00000374076.4
 TMEM222
 transmembrane protein 222
chr1_+_27648709 0.02 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
 TMEM222
 transmembrane protein 222
chr19_-_2739992 0.02 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
 SLC39A3
 solute carrier family 39 (zinc transporter), member 3
chr10_+_98592674 0.02 ENST00000356016.3
ENST00000371097.4
 LCOR
 ligand dependent nuclear receptor corepressor
chr2_+_1488435 0.02 ENST00000446278.1
ENST00000469607.1
 TPO
 thyroid peroxidase
chr9_+_103189660 0.02 ENST00000374886.3
 MSANTD3
 Myb/SANT-like DNA-binding domain containing 3
chr20_-_62199427 0.01 ENST00000427522.2
 HELZ2
 helicase with zinc finger 2, transcriptional coactivator
chr4_+_39460620 0.01 ENST00000340169.2
ENST00000261434.3
 LIAS
 lipoic acid synthetase
chr22_-_37640456 0.01 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr20_-_3644046 0.01 ENST00000290417.2
ENST00000319242.3
 GFRA4
 GDNF family receptor alpha 4
chr3_+_184081175 0.01 ENST00000452961.1
ENST00000296223.3
 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
chr4_-_176733897 0.01 ENST00000393658.2
 GPM6A
 glycoprotein M6A
chr14_-_67981870 0.01 ENST00000555994.1
 TMEM229B
 transmembrane protein 229B
chr17_-_26684473 0.01 ENST00000540200.1
 POLDIP2
 polymerase (DNA-directed), delta interacting protein 2
chr11_+_70049269 0.01 ENST00000301838.4
 FADD
 Fas (TNFRSF6)-associated via death domain
chr3_+_184081213 0.01 ENST00000429568.1
 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
chr19_-_344786 0.01 ENST00000264819.4
 MIER2
 mesoderm induction early response 1, family member 2
chr2_+_101179152 0.01 ENST00000264254.6
 PDCL3
 phosducin-like 3
chrX_+_109245863 0.01 ENST00000372072.3
 TMEM164
 transmembrane protein 164
chr11_-_64739542 0.01 ENST00000536065.1
 C11orf85
 chromosome 11 open reading frame 85
chr14_-_76447336 0.01 ENST00000556285.1
 TGFB3
 transforming growth factor, beta 3
chr7_+_87563458 0.01 ENST00000398204.4
 ADAM22
 ADAM metallopeptidase domain 22
chr2_+_69201705 0.01 ENST00000377938.2
 GKN1
 gastrokine 1
chr16_-_46797149 0.01 ENST00000536476.1
 MYLK3
 myosin light chain kinase 3
chr20_-_48770244 0.01 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
 TMEM189
 transmembrane protein 189
chr15_+_89921280 0.01 ENST00000560596.1
ENST00000558692.1
ENST00000538734.2
ENST00000559235.1
 LINC00925
 long intergenic non-protein coding RNA 925
chr14_+_54976603 0.01 ENST00000557317.1
 CGRRF1
 cell growth regulator with ring finger domain 1
chr11_-_61197480 0.01 ENST00000439958.3
ENST00000394888.4
 CPSF7
 cleavage and polyadenylation specific factor 7, 59kDa
chr1_-_205391178 0.01 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
 LEMD1
 LEM domain containing 1
chr6_-_33160231 0.01 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
 COL11A2
 collagen, type XI, alpha 2
chr21_+_46066331 0.01 ENST00000334670.8
 KRTAP10-11
 keratin associated protein 10-11
chr3_+_38388251 0.01 ENST00000427323.1
ENST00000207870.3
ENST00000542835.1
 XYLB
 xylulokinase homolog (H. influenzae)
chr22_+_20861858 0.00 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
 MED15
 mediator complex subunit 15
chr4_-_13549417 0.00 ENST00000501050.1
 AC006445.8
 long intergenic non-protein coding RNA 1096
chr11_-_64739358 0.00 ENST00000301896.5
ENST00000530444.1
 C11orf85
 chromosome 11 open reading frame 85
chr13_+_76445187 0.00 ENST00000318245.4
 C13orf45
 chromosome 13 open reading frame 45
chr11_+_64808675 0.00 ENST00000529996.1
 SAC3D1
 SAC3 domain containing 1
chr1_-_36615065 0.00 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
 TRAPPC3
 trafficking protein particle complex 3
chr2_-_37193606 0.00 ENST00000379213.2
ENST00000263918.4
 STRN
 striatin, calmodulin binding protein
chr22_-_38484922 0.00 ENST00000428572.1
 BAIAP2L2
 BAI1-associated protein 2-like 2
chr1_-_36615051 0.00 ENST00000373163.1
 TRAPPC3
 trafficking protein particle complex 3
chr3_+_184081137 0.00 ENST00000443489.1
 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
chr5_-_134735568 0.00 ENST00000510038.1
ENST00000304332.4
 H2AFY
 H2A histone family, member Y

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)