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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ZNF350

Z-value: 0.24

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 ZNF350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_52490113-0.373.6e-01Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_39674668 0.34 ENST00000393981.3
 KRT15
 keratin 15
chr14_+_96671016 0.16 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
 BDKRB2
RP11-404P21.8
 bradykinin receptor B2
Uncharacterized protein
chr10_+_50822480 0.16 ENST00000455728.2
 CHAT
 choline O-acetyltransferase
chr11_-_112034803 0.13 ENST00000528832.1
 IL18
 interleukin 18 (interferon-gamma-inducing factor)
chr11_-_112034780 0.13 ENST00000524595.1
 IL18
 interleukin 18 (interferon-gamma-inducing factor)
chr11_-_112034831 0.13 ENST00000280357.7
 IL18
 interleukin 18 (interferon-gamma-inducing factor)
chr2_-_70780770 0.12 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA
 transforming growth factor, alpha
chr2_-_70780572 0.12 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr12_+_113376157 0.11 ENST00000228928.7
 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
chr9_+_12693336 0.07 ENST00000381137.2
ENST00000388918.5
 TYRP1
 tyrosinase-related protein 1
chr1_+_156119798 0.07 ENST00000355014.2
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr10_+_50822083 0.06 ENST00000337653.2
ENST00000395562.2
 CHAT
 choline O-acetyltransferase
chr11_-_69633792 0.06 ENST00000334134.2
 FGF3
 fibroblast growth factor 3
chr1_-_200379129 0.06 ENST00000367353.1
 ZNF281
 zinc finger protein 281
chr11_+_118826999 0.05 ENST00000264031.2
 UPK2
 uroplakin 2
chr4_+_120133791 0.05 ENST00000274030.6
 USP53
 ubiquitin specific peptidase 53
chr1_-_200379180 0.05 ENST00000294740.3
 ZNF281
 zinc finger protein 281
chr1_-_46089718 0.05 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
 CCDC17
 coiled-coil domain containing 17
chr9_+_124329336 0.05 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
 DAB2IP
 DAB2 interacting protein
chr1_-_204654481 0.05 ENST00000367176.3
 LRRN2
 leucine rich repeat neuronal 2
chr11_-_9113093 0.04 ENST00000450649.2
 SCUBE2
 signal peptide, CUB domain, EGF-like 2
chr1_-_200379104 0.04 ENST00000367352.3
 ZNF281
 zinc finger protein 281
chr12_-_93323013 0.04 ENST00000322349.8
 EEA1
 early endosome antigen 1
chr12_+_50451462 0.04 ENST00000447966.2
 ASIC1
 acid-sensing (proton-gated) ion channel 1
chr2_-_9143786 0.04 ENST00000462696.1
ENST00000305997.3
 MBOAT2
 membrane bound O-acyltransferase domain containing 2
chr21_-_30365136 0.04 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
 LTN1
 listerin E3 ubiquitin protein ligase 1
chr12_+_113376249 0.04 ENST00000551007.1
ENST00000548514.1
 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
chr20_-_54580523 0.04 ENST00000064571.2
 CBLN4
 cerebellin 4 precursor
chr13_-_96329048 0.04 ENST00000606011.1
ENST00000499499.2
 DNAJC3-AS1
 DNAJC3 antisense RNA 1 (head to head)
chr8_-_119124045 0.04 ENST00000378204.2
 EXT1
 exostosin glycosyltransferase 1
chr8_+_144295067 0.04 ENST00000330824.2
 GPIHBP1
 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr4_+_75858290 0.04 ENST00000513238.1
 PARM1
 prostate androgen-regulated mucin-like protein 1
chr13_+_96329381 0.04 ENST00000602402.1
ENST00000376795.6
 DNAJC3
 DnaJ (Hsp40) homolog, subfamily C, member 3
chr20_+_4666882 0.04 ENST00000379440.4
ENST00000430350.2
 PRNP
 prion protein
chr2_-_106810783 0.03 ENST00000283148.7
 UXS1
 UDP-glucuronate decarboxylase 1
chr4_+_75858318 0.03 ENST00000307428.7
 PARM1
 prostate androgen-regulated mucin-like protein 1
chr12_+_50451331 0.03 ENST00000228468.4
 ASIC1
 acid-sensing (proton-gated) ion channel 1
chr16_-_74734672 0.03 ENST00000306247.7
ENST00000575686.1
 MLKL
 mixed lineage kinase domain-like
chr17_-_74449252 0.03 ENST00000319380.7
 UBE2O
 ubiquitin-conjugating enzyme E2O
chr2_-_106810742 0.03 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
 UXS1
 UDP-glucuronate decarboxylase 1
chr1_+_63788730 0.03 ENST00000371116.2
 FOXD3
 forkhead box D3
chr20_+_4667094 0.03 ENST00000424424.1
ENST00000457586.1
 PRNP
 prion protein
chr2_-_219157250 0.03 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
 TMBIM1
 transmembrane BAX inhibitor motif containing 1
chr19_+_35645618 0.03 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
 FXYD5
 FXYD domain containing ion transport regulator 5
chr3_-_155524049 0.03 ENST00000534941.1
ENST00000340171.2
 C3orf33
 chromosome 3 open reading frame 33
chr2_+_177025619 0.03 ENST00000410016.1
 HOXD3
 homeobox D3
chr10_-_15762124 0.03 ENST00000378076.3
 ITGA8
 integrin, alpha 8
chr16_+_2479390 0.03 ENST00000397066.4
 CCNF
 cyclin F
chr11_-_9113137 0.03 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
 SCUBE2
 signal peptide, CUB domain, EGF-like 2
chr17_-_39597173 0.03 ENST00000246646.3
 KRT38
 keratin 38
chr15_+_42694573 0.03 ENST00000397200.4
ENST00000569827.1
 CAPN3
 calpain 3, (p94)
chr12_+_81471816 0.03 ENST00000261206.3
 ACSS3
 acyl-CoA synthetase short-chain family member 3
chr1_-_247094628 0.03 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
 AHCTF1
 AT hook containing transcription factor 1
chr17_+_68071389 0.03 ENST00000283936.1
ENST00000392671.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr18_+_77155942 0.03 ENST00000397790.2
 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr16_-_74734742 0.03 ENST00000308807.7
ENST00000573267.1
 MLKL
 mixed lineage kinase domain-like
chr4_-_76008706 0.03 ENST00000562355.1
ENST00000563602.1
 RP11-44F21.5
 RP11-44F21.5
chr1_-_46089639 0.02 ENST00000445048.2
 CCDC17
 coiled-coil domain containing 17
chr10_-_12084770 0.02 ENST00000357604.5
 UPF2
 UPF2 regulator of nonsense transcripts homolog (yeast)
chr3_+_113775576 0.02 ENST00000485050.1
ENST00000281273.4
 QTRTD1
 queuine tRNA-ribosyltransferase domain containing 1
chr19_+_35645817 0.02 ENST00000423817.3
 FXYD5
 FXYD domain containing ion transport regulator 5
chr16_+_4526341 0.02 ENST00000458134.3
ENST00000219700.6
ENST00000575120.1
ENST00000572812.1
ENST00000574466.1
ENST00000576827.1
ENST00000570445.1
 HMOX2
 heme oxygenase (decycling) 2
chr1_+_156611704 0.02 ENST00000329117.5
 BCAN
 brevican
chr16_+_67282853 0.02 ENST00000299798.11
 SLC9A5
 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr15_-_65477637 0.02 ENST00000300107.3
 CLPX
 caseinolytic mitochondrial matrix peptidase chaperone subunit
chr17_+_68071458 0.02 ENST00000589377.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr14_-_94254821 0.02 ENST00000393140.1
 PRIMA1
 proline rich membrane anchor 1
chr22_+_26565440 0.02 ENST00000404234.3
ENST00000529632.2
ENST00000360929.3
ENST00000248933.6
ENST00000343706.4
 SEZ6L
 seizure related 6 homolog (mouse)-like
chr3_-_128212016 0.02 ENST00000498200.1
ENST00000341105.2
 GATA2
 GATA binding protein 2
chr18_+_77155856 0.02 ENST00000253506.5
ENST00000591814.1
 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_+_7041677 0.02 ENST00000299481.4
 NLRP14
 NLR family, pyrin domain containing 14
chr1_+_204797749 0.02 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
 NFASC
 neurofascin
chr2_+_238600788 0.02 ENST00000289175.6
ENST00000244815.5
 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
chr3_-_11623804 0.01 ENST00000451674.2
 VGLL4
 vestigial like 4 (Drosophila)
chr5_+_176514413 0.01 ENST00000513166.1
 FGFR4
 fibroblast growth factor receptor 4
chr12_-_109219937 0.01 ENST00000546697.1
 SSH1
 slingshot protein phosphatase 1
chr8_-_100905363 0.01 ENST00000524245.1
 COX6C
 cytochrome c oxidase subunit VIc
chr11_-_7041466 0.01 ENST00000536068.1
ENST00000278314.4
 ZNF214
 zinc finger protein 214
chr3_-_128902759 0.01 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
chrX_+_56259316 0.01 ENST00000468660.1
 KLF8
 Kruppel-like factor 8
chr5_-_93077293 0.01 ENST00000510627.4
 POU5F2
 POU domain class 5, transcription factor 2
chrX_-_120090454 0.01 ENST00000434883.2
 CT47A7
 cancer/testis antigen family 47, member A7
chr11_+_48002076 0.01 ENST00000418331.2
ENST00000440289.2
 PTPRJ
 protein tyrosine phosphatase, receptor type, J
chr16_+_71879861 0.01 ENST00000427980.2
ENST00000568581.1
 ATXN1L
IST1
 ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr17_-_39968855 0.01 ENST00000355468.3
ENST00000590496.1
 LEPREL4
 leprecan-like 4
chr4_-_174255400 0.01 ENST00000506267.1
 HMGB2
 high mobility group box 2
chr11_+_64323428 0.01 ENST00000377581.3
 SLC22A11
 solute carrier family 22 (organic anion/urate transporter), member 11
chr1_+_156611960 0.01 ENST00000361588.5
 BCAN
 brevican
chr19_+_5681011 0.01 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
 HSD11B1L
 hydroxysteroid (11-beta) dehydrogenase 1-like
chr15_-_43029252 0.01 ENST00000563260.1
ENST00000356231.3
 CDAN1
 codanin 1
chr17_+_48624450 0.01 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20
 spermatogenesis associated 20
chr3_-_128902729 0.01 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
chr18_+_45778672 0.01 ENST00000600091.1
 AC091150.1
 HCG1818186; Uncharacterized protein
chr3_+_50229037 0.01 ENST00000232461.3
ENST00000433068.1
 GNAT1
 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr17_+_7487146 0.01 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
 MPDU1
 mannose-P-dolichol utilization defect 1
chr2_-_157198860 0.01 ENST00000409572.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr4_-_174255536 0.01 ENST00000446922.2
 HMGB2
 high mobility group box 2
chr1_+_22970119 0.01 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
 C1QC
 complement component 1, q subcomponent, C chain
chr17_-_18950950 0.01 ENST00000284154.5
 GRAP
 GRB2-related adaptor protein
chrX_-_47479246 0.00 ENST00000295987.7
ENST00000340666.4
 SYN1
 synapsin I
chr19_+_42829702 0.00 ENST00000334370.4
 MEGF8
 multiple EGF-like-domains 8
chr19_+_1450112 0.00 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
 APC2
 adenomatosis polyposis coli 2
chr1_+_228395755 0.00 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
 OBSCN
 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr19_+_5681153 0.00 ENST00000579559.1
ENST00000577222.1
 HSD11B1L
RPL36
 hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr3_-_113775328 0.00 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
 KIAA1407
 KIAA1407
chr11_+_68671310 0.00 ENST00000255078.3
ENST00000539224.1
 IGHMBP2
 immunoglobulin mu binding protein 2
chrX_-_17878827 0.00 ENST00000360011.1
 RAI2
 retinoic acid induced 2
chr14_+_73603126 0.00 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
 PSEN1
 presenilin 1
chr17_-_79881408 0.00 ENST00000392366.3
 MAFG
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr20_+_44035847 0.00 ENST00000372712.2
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:1990032 parallel fiber(GO:1990032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle