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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ZNF8

Z-value: 0.20

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Transcription factors associated with ZNF8

Gene Symbol Gene ID Gene Info
ENSG00000083842.8 ZNF8
ENSG00000273439.1 ZNF8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_58790358-0.686.5e-02Click!

Activity profile of ZNF8 motif

Sorted Z-values of ZNF8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_35739897 0.19 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739782 0.18 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr19_-_55652290 0.17 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr1_-_55266926 0.09 ENST00000371276.4
TTC22
tetratricopeptide repeat domain 22
chr17_+_48585745 0.07 ENST00000323776.5
MYCBPAP
MYCBP associated protein
chr6_+_53659746 0.07 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr11_-_58345569 0.06 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr6_+_18155560 0.05 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B
lysine (K)-specific demethylase 1B
chrX_+_128913906 0.05 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr7_+_1748798 0.03 ENST00000561626.1
ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr6_+_116601265 0.03 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr6_-_26056695 0.03 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr17_+_34136459 0.03 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr1_-_55266865 0.03 ENST00000371274.4
TTC22
tetratricopeptide repeat domain 22
chr6_+_29691198 0.03 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr2_-_172290482 0.03 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8
methyltransferase like 8
chr11_+_13690249 0.03 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr22_+_37415700 0.03 ENST00000397129.1
MPST
mercaptopyruvate sulfurtransferase
chr22_+_37415676 0.03 ENST00000401419.3
MPST
mercaptopyruvate sulfurtransferase
chr22_+_37415728 0.03 ENST00000404802.3
MPST
mercaptopyruvate sulfurtransferase
chr6_+_29691056 0.02 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr2_-_105946491 0.02 ENST00000393359.2
TGFBRAP1
transforming growth factor, beta receptor associated protein 1
chr22_+_37415776 0.02 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
MPST
mercaptopyruvate sulfurtransferase
chr4_+_24797085 0.02 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr1_-_246670519 0.02 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr2_+_172290707 0.02 ENST00000375255.3
ENST00000539783.1
DCAF17
DDB1 and CUL4 associated factor 17
chrX_+_129535937 0.02 ENST00000305536.6
ENST00000370947.1
RBMX2
RNA binding motif protein, X-linked 2
chr10_+_1034646 0.02 ENST00000360059.5
ENST00000545048.1
GTPBP4
GTP binding protein 4
chr1_-_100715372 0.01 ENST00000370131.3
ENST00000370132.4
DBT
dihydrolipoamide branched chain transacylase E2
chr11_+_13690200 0.01 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr7_-_74489609 0.01 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
WBSCR16
Williams-Beuren syndrome chromosome region 16
chr16_+_21964662 0.01 ENST00000561553.1
ENST00000565331.1
UQCRC2
ubiquinol-cytochrome c reductase core protein II
chr8_+_145064233 0.01 ENST00000529301.1
ENST00000395068.4
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_31763408 0.01 ENST00000444930.2
VARS
valyl-tRNA synthetase
chr8_-_109260897 0.01 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E
eukaryotic translation initiation factor 3, subunit E
chr7_+_117824086 0.01 ENST00000249299.2
ENST00000424702.1
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr6_+_31939608 0.01 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr17_-_27169745 0.01 ENST00000583307.1
ENST00000581229.1
ENST00000582266.1
ENST00000577376.1
ENST00000577682.1
ENST00000581381.1
ENST00000341217.5
ENST00000581407.1
ENST00000583522.1
FAM222B
family with sequence similarity 222, member B
chr1_-_235292250 0.01 ENST00000366607.4
TOMM20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr5_+_138677515 0.01 ENST00000265192.4
ENST00000511706.1
PAIP2
poly(A) binding protein interacting protein 2
chr1_+_214161272 0.01 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr17_-_45908875 0.01 ENST00000351111.2
ENST00000414011.1
MRPL10
mitochondrial ribosomal protein L10
chr7_+_100303676 0.01 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr14_+_51706886 0.01 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr12_-_46662772 0.01 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
SLC38A1
solute carrier family 38, member 1
chrX_+_1387693 0.01 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
CSF2RA
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr11_+_46638805 0.01 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
ATG13
autophagy related 13
chr15_+_85523671 0.01 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr12_-_74686314 0.00 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr22_+_30163340 0.00 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr9_+_96026230 0.00 ENST00000448251.1
WNK2
WNK lysine deficient protein kinase 2
chr2_-_240322643 0.00 ENST00000345617.3
HDAC4
histone deacetylase 4
chr11_+_46402583 0.00 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr13_-_21750659 0.00 ENST00000400018.3
ENST00000314759.5
SKA3
spindle and kinetochore associated complex subunit 3
chr2_+_198365122 0.00 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr22_-_30162924 0.00 ENST00000344318.3
ENST00000397781.3
ZMAT5
zinc finger, matrin-type 5
chr12_+_52463751 0.00 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
C12orf44
chromosome 12 open reading frame 44
chr6_+_88117683 0.00 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr19_-_5903714 0.00 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr13_+_21750780 0.00 ENST00000309594.4
MRP63
mitochondrial ribosomal protein 63
chr19_+_37998031 0.00 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
ZNF793
zinc finger protein 793
chr8_+_61429416 0.00 ENST00000262646.7
ENST00000531289.1
RAB2A
RAB2A, member RAS oncogene family
chr12_-_122750957 0.00 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr16_+_68573116 0.00 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
ZFP90
ZFP90 zinc finger protein
chr9_-_32552551 0.00 ENST00000360538.2
ENST00000379858.1
TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)