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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for AIRE

Z-value: 0.68

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Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
AIRE
ENSG00000160224.12 AIRE

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AIREhg19_v2_chr21_+_45705752_457057670.167.0e-01Click!

Activity profile of AIRE motif

Sorted Z-values of AIRE motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_90112117 0.96 ENST00000358077.5
 DAPK1
 death-associated protein kinase 1
chr12_-_15038779 0.94 ENST00000228938.5
ENST00000539261.1
 MGP
 matrix Gla protein
chr2_-_225811747 0.85 ENST00000409592.3
 DOCK10
 dedicator of cytokinesis 10
chr4_-_57524061 0.81 ENST00000508121.1
 HOPX
 HOP homeobox
chr8_+_104384616 0.77 ENST00000520337.1
 CTHRC1
 collagen triple helix repeat containing 1
chr12_+_75874984 0.67 ENST00000550491.1
 GLIPR1
 GLI pathogenesis-related 1
chr20_+_12989596 0.55 ENST00000434210.1
ENST00000399002.2
 SPTLC3
 serine palmitoyltransferase, long chain base subunit 3
chr6_-_31514333 0.53 ENST00000376151.4
 ATP6V1G2
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr5_+_32788945 0.52 ENST00000326958.1
 AC026703.1
 AC026703.1
chr12_+_75874580 0.49 ENST00000456650.3
 GLIPR1
 GLI pathogenesis-related 1
chr4_-_186696425 0.48 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr1_-_243326612 0.46 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
 CEP170
 centrosomal protein 170kDa
chr6_-_31514516 0.45 ENST00000303892.5
ENST00000483251.1
 ATP6V1G2
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr12_+_75874460 0.42 ENST00000266659.3
 GLIPR1
 GLI pathogenesis-related 1
chr12_+_55248289 0.42 ENST00000308796.6
 MUCL1
 mucin-like 1
chr9_-_113761720 0.37 ENST00000541779.1
ENST00000374430.2
 LPAR1
 lysophosphatidic acid receptor 1
chr9_-_21482312 0.37 ENST00000448696.3
 IFNE
 interferon, epsilon
chr10_+_90660832 0.35 ENST00000371924.1
 STAMBPL1
 STAM binding protein-like 1
chr19_-_52551814 0.31 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
 ZNF432
 zinc finger protein 432
chr1_+_79115503 0.29 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44
 interferon-induced protein 44
chr5_+_72143988 0.26 ENST00000506351.2
 TNPO1
 transportin 1
chrX_-_100307076 0.26 ENST00000338687.7
ENST00000545398.1
ENST00000372931.5
 TRMT2B
 tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr20_-_33735070 0.25 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
 EDEM2
 ER degradation enhancer, mannosidase alpha-like 2
chrX_-_100307043 0.25 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
 TRMT2B
 tRNA methyltransferase 2 homolog B (S. cerevisiae)
chrM_+_12331 0.24 ENST00000361567.2
 MT-ND5
 mitochondrially encoded NADH dehydrogenase 5
chr3_-_49466686 0.24 ENST00000273598.3
ENST00000436744.2
 NICN1
 nicolin 1
chr10_-_106240032 0.24 ENST00000447860.1
 RP11-127O4.3
 RP11-127O4.3
chr5_+_140625147 0.23 ENST00000231173.3
 PCDHB15
 protocadherin beta 15
chr19_+_11455900 0.23 ENST00000588790.1
 CCDC159
 coiled-coil domain containing 159
chr19_-_48752812 0.22 ENST00000359009.4
 CARD8
 caspase recruitment domain family, member 8
chr6_+_36839616 0.22 ENST00000359359.2
ENST00000510325.2
 C6orf89
 chromosome 6 open reading frame 89
chr2_-_166060571 0.22 ENST00000360093.3
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr12_-_6580094 0.22 ENST00000361716.3
 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
chr13_+_50570019 0.22 ENST00000442421.1
 TRIM13
 tripartite motif containing 13
chr19_-_48753104 0.21 ENST00000447740.2
 CARD8
 caspase recruitment domain family, member 8
chr1_+_174843548 0.21 ENST00000478442.1
ENST00000465412.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr4_-_114682936 0.20 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
chr2_-_166060552 0.20 ENST00000283254.7
ENST00000453007.1
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr16_+_32077386 0.18 ENST00000354689.6
 IGHV3OR16-9
 immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr9_-_114361665 0.17 ENST00000309195.5
 PTGR1
 prostaglandin reductase 1
chr8_-_7220490 0.17 ENST00000400078.2
 ZNF705G
 zinc finger protein 705G
chr4_-_66536057 0.17 ENST00000273854.3
 EPHA5
 EPH receptor A5
chr15_+_27112948 0.17 ENST00000555060.1
 GABRA5
 gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr17_-_295730 0.16 ENST00000329099.4
 FAM101B
 family with sequence similarity 101, member B
chr19_+_18208603 0.16 ENST00000262811.6
 MAST3
 microtubule associated serine/threonine kinase 3
chr19_-_23869999 0.16 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
 ZNF675
 zinc finger protein 675
chr12_-_6579808 0.15 ENST00000535180.1
ENST00000400911.3
 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
chr9_-_114362093 0.15 ENST00000538962.1
ENST00000407693.2
ENST00000238248.3
 PTGR1
 prostaglandin reductase 1
chr2_+_179316163 0.14 ENST00000409117.3
 DFNB59
 deafness, autosomal recessive 59
chr2_+_201981527 0.14 ENST00000441224.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr7_-_87936195 0.14 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
 STEAP4
 STEAP family member 4
chr10_-_101841588 0.14 ENST00000370418.3
 CPN1
 carboxypeptidase N, polypeptide 1
chr9_-_114361919 0.13 ENST00000422125.1
 PTGR1
 prostaglandin reductase 1
chr5_-_107703556 0.13 ENST00000496714.1
 FBXL17
 F-box and leucine-rich repeat protein 17
chr9_-_4666421 0.13 ENST00000381895.5
 SPATA6L
 spermatogenesis associated 6-like
chr14_-_24911971 0.11 ENST00000555365.1
ENST00000399395.3
 SDR39U1
 short chain dehydrogenase/reductase family 39U, member 1
chr8_+_105352050 0.11 ENST00000297581.2
 DCSTAMP
 dendrocyte expressed seven transmembrane protein
chr12_+_52643077 0.11 ENST00000553310.2
ENST00000544024.1
 KRT86
 keratin 86
chr16_+_14802801 0.11 ENST00000526520.1
ENST00000531598.2
 NPIPA3
 nuclear pore complex interacting protein family, member A3
chr16_+_3254247 0.11 ENST00000304646.2
 OR1F1
 olfactory receptor, family 1, subfamily F, member 1
chr14_+_58894706 0.11 ENST00000261244.5
 KIAA0586
 KIAA0586
chr1_-_145826450 0.11 ENST00000462900.2
 GPR89A
 G protein-coupled receptor 89A
chr3_-_19975665 0.10 ENST00000295824.9
ENST00000389256.4
 EFHB
 EF-hand domain family, member B
chr1_+_152627927 0.10 ENST00000444515.1
ENST00000536536.1
 LINC00302
 long intergenic non-protein coding RNA 302
chr2_+_172864490 0.10 ENST00000315796.4
 METAP1D
 methionyl aminopeptidase type 1D (mitochondrial)
chrM_-_14670 0.10 ENST00000361681.2
 MT-ND6
 mitochondrially encoded NADH dehydrogenase 6
chr4_-_104119528 0.10 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
 CENPE
 centromere protein E, 312kDa
chr2_-_202508169 0.10 ENST00000409883.2
 TMEM237
 transmembrane protein 237
chr5_+_122181184 0.09 ENST00000513881.1
 SNX24
 sorting nexin 24
chr16_-_71518504 0.09 ENST00000565100.2
 ZNF19
 zinc finger protein 19
chr2_+_166150541 0.09 ENST00000283256.6
 SCN2A
 sodium channel, voltage-gated, type II, alpha subunit
chr5_+_122181279 0.09 ENST00000395451.4
ENST00000506996.1
 SNX24
 sorting nexin 24
chr22_+_40322595 0.09 ENST00000420971.1
ENST00000544756.1
 GRAP2
 GRB2-related adaptor protein 2
chr15_+_52043758 0.09 ENST00000249700.4
ENST00000539962.2
 TMOD2
 tropomodulin 2 (neuronal)
chr19_-_23869970 0.09 ENST00000601010.1
 ZNF675
 zinc finger protein 675
chr22_+_40322623 0.08 ENST00000399090.2
 GRAP2
 GRB2-related adaptor protein 2
chr14_-_24912047 0.08 ENST00000553930.1
 SDR39U1
 short chain dehydrogenase/reductase family 39U, member 1
chr3_+_189507460 0.08 ENST00000434928.1
 TP63
 tumor protein p63
chr11_+_30252549 0.08 ENST00000254122.3
ENST00000417547.1
 FSHB
 follicle stimulating hormone, beta polypeptide
chr8_-_7309887 0.08 ENST00000458665.1
ENST00000528168.1
 SPAG11B
 sperm associated antigen 11B
chr17_-_38721711 0.08 ENST00000578085.1
ENST00000246657.2
 CCR7
 chemokine (C-C motif) receptor 7
chr14_-_55658323 0.07 ENST00000554067.1
ENST00000247191.2
 DLGAP5
 discs, large (Drosophila) homolog-associated protein 5
chr13_+_103459704 0.07 ENST00000602836.1
 BIVM-ERCC5
 BIVM-ERCC5 readthrough
chr3_-_123710199 0.07 ENST00000184183.4
 ROPN1
 rhophilin associated tail protein 1
chr20_-_43150601 0.07 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
 SERINC3
 serine incorporator 3
chr5_+_122181128 0.07 ENST00000261369.4
 SNX24
 sorting nexin 24
chr19_+_11708259 0.07 ENST00000587939.1
ENST00000588174.1
 ZNF627
 zinc finger protein 627
chr11_+_64794875 0.07 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
 SNX15
 sorting nexin 15
chr19_-_36643329 0.07 ENST00000589154.1
 COX7A1
 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr8_+_7716700 0.07 ENST00000454911.2
ENST00000326625.5
 SPAG11A
 sperm associated antigen 11A
chr4_+_78829479 0.07 ENST00000504901.1
 MRPL1
 mitochondrial ribosomal protein L1
chr12_-_76462713 0.06 ENST00000552056.1
 NAP1L1
 nucleosome assembly protein 1-like 1
chr3_+_88199099 0.06 ENST00000486971.1
 C3orf38
 chromosome 3 open reading frame 38
chr4_+_1385340 0.06 ENST00000324803.4
 CRIPAK
 cysteine-rich PAK1 inhibitor
chr19_-_59084922 0.06 ENST00000215057.2
ENST00000599369.1
 MZF1
 myeloid zinc finger 1
chr18_-_37380230 0.06 ENST00000591629.1
 LINC00669
 long intergenic non-protein coding RNA 669
chr1_-_35497506 0.06 ENST00000317538.5
ENST00000373340.2
ENST00000357182.4
 ZMYM6
 zinc finger, MYM-type 6
chrX_-_102941596 0.06 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
 MORF4L2
 mortality factor 4 like 2
chr22_+_36649056 0.06 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
 APOL1
 apolipoprotein L, 1
chr11_+_6947647 0.06 ENST00000278319.5
 ZNF215
 zinc finger protein 215
chr7_-_55606346 0.06 ENST00000545390.1
 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
chr5_+_118690466 0.06 ENST00000503646.1
 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
chr17_+_3323862 0.06 ENST00000291231.1
 OR3A3
 olfactory receptor, family 3, subfamily A, member 3
chr14_-_55658252 0.05 ENST00000395425.2
 DLGAP5
 discs, large (Drosophila) homolog-associated protein 5
chr19_-_10491234 0.05 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
 TYK2
 tyrosine kinase 2
chr11_-_18956556 0.05 ENST00000302797.3
 MRGPRX1
 MAS-related GPR, member X1
chr17_+_41857793 0.05 ENST00000449302.3
 C17orf105
 chromosome 17 open reading frame 105
chr3_-_139199565 0.05 ENST00000511956.1
 RBP2
 retinol binding protein 2, cellular
chr8_+_54764346 0.05 ENST00000297313.3
ENST00000344277.6
 RGS20
 regulator of G-protein signaling 20
chr15_-_99789736 0.05 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
 TTC23
 tetratricopeptide repeat domain 23
chr19_+_45418067 0.05 ENST00000589078.1
ENST00000586638.1
 APOC1
 apolipoprotein C-I
chr7_-_64023441 0.05 ENST00000309683.6
 ZNF680
 zinc finger protein 680
chr4_+_71587669 0.05 ENST00000381006.3
ENST00000226328.4
 RUFY3
 RUN and FYVE domain containing 3
chr4_+_76649797 0.05 ENST00000538159.1
ENST00000514213.2
 USO1
 USO1 vesicle transport factor
chr16_+_446713 0.05 ENST00000397722.1
ENST00000454619.1
 NME4
 NME/NM23 nucleoside diphosphate kinase 4
chrM_+_7586 0.05 ENST00000361739.1
 MT-CO2
 mitochondrially encoded cytochrome c oxidase II
chr3_+_39424828 0.05 ENST00000273158.4
ENST00000431510.1
 SLC25A38
 solute carrier family 25, member 38
chr12_-_75603482 0.05 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
 KCNC2
 potassium voltage-gated channel, Shaw-related subfamily, member 2
chr19_-_35719609 0.05 ENST00000324675.3
 FAM187B
 family with sequence similarity 187, member B
chr3_-_121468513 0.04 ENST00000494517.1
ENST00000393667.3
 GOLGB1
 golgin B1
chr12_-_6579833 0.04 ENST00000396308.3
 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
chr17_+_77030267 0.04 ENST00000581774.1
 C1QTNF1
 C1q and tumor necrosis factor related protein 1
chr19_-_21950362 0.04 ENST00000358296.6
 ZNF100
 zinc finger protein 100
chrM_+_5824 0.04 ENST00000361624.2
 MT-CO1
 mitochondrially encoded cytochrome c oxidase I
chr8_-_145652336 0.04 ENST00000529182.1
ENST00000526054.1
 VPS28
 vacuolar protein sorting 28 homolog (S. cerevisiae)
chr3_-_121468602 0.04 ENST00000340645.5
 GOLGB1
 golgin B1
chr12_-_11287243 0.04 ENST00000539585.1
 TAS2R30
 taste receptor, type 2, member 30
chr19_+_45417921 0.04 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
 APOC1
 apolipoprotein C-I
chr3_-_133648656 0.04 ENST00000408895.2
 C3orf36
 chromosome 3 open reading frame 36
chr7_-_137028498 0.04 ENST00000393083.2
 PTN
 pleiotrophin
chr1_+_100810575 0.04 ENST00000542213.1
 CDC14A
 cell division cycle 14A
chr16_+_56672571 0.04 ENST00000290705.8
 MT1A
 metallothionein 1A
chr2_-_136633940 0.04 ENST00000264156.2
 MCM6
 minichromosome maintenance complex component 6
chr12_+_12223867 0.03 ENST00000308721.5
 BCL2L14
 BCL2-like 14 (apoptosis facilitator)
chr16_+_50059125 0.03 ENST00000427478.2
 CNEP1R1
 CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr4_+_71588372 0.03 ENST00000536664.1
 RUFY3
 RUN and FYVE domain containing 3
chr12_+_12202774 0.03 ENST00000589718.1
 BCL2L14
 BCL2-like 14 (apoptosis facilitator)
chr2_+_38177575 0.03 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
 RMDN2
 regulator of microtubule dynamics 2
chr1_+_207669573 0.03 ENST00000400960.2
ENST00000534202.1
 CR1
 complement component (3b/4b) receptor 1 (Knops blood group)
chr12_-_59175485 0.03 ENST00000550678.1
ENST00000552201.1
 RP11-767I20.1
 RP11-767I20.1
chr12_+_12202785 0.03 ENST00000586576.1
ENST00000464885.2
 BCL2L14
 BCL2-like 14 (apoptosis facilitator)
chr7_-_15601595 0.03 ENST00000342526.3
 AGMO
 alkylglycerol monooxygenase
chr1_+_47603109 0.03 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
 CYP4A22
 cytochrome P450, family 4, subfamily A, polypeptide 22
chr17_-_42019836 0.03 ENST00000225992.3
 PPY
 pancreatic polypeptide
chr7_-_137028534 0.03 ENST00000348225.2
 PTN
 pleiotrophin
chr6_+_118869452 0.03 ENST00000357525.5
 PLN
 phospholamban
chr12_-_11463353 0.03 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
 PRB4
 proline-rich protein BstNI subfamily 4
chrX_-_139866723 0.03 ENST00000370532.2
 CDR1
 cerebellar degeneration-related protein 1, 34kDa
chr20_+_21284416 0.02 ENST00000539513.1
 XRN2
 5'-3' exoribonuclease 2
chr22_+_42017987 0.02 ENST00000405506.1
 XRCC6
 X-ray repair complementing defective repair in Chinese hamster cells 6
chr5_+_141488070 0.02 ENST00000253814.4
 NDFIP1
 Nedd4 family interacting protein 1
chr1_+_36038971 0.02 ENST00000373235.3
 TFAP2E
 transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr3_+_193965426 0.02 ENST00000455821.1
 RP11-513G11.3
 RP11-513G11.3
chr21_-_44495919 0.02 ENST00000398158.1
 CBS
 cystathionine-beta-synthase
chr14_-_46185155 0.02 ENST00000555442.1
 RP11-369C8.1
 RP11-369C8.1
chrX_+_70503433 0.02 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
 NONO
 non-POU domain containing, octamer-binding
chr4_-_17513851 0.02 ENST00000281243.5
 QDPR
 quinoid dihydropteridine reductase
chr11_-_327537 0.02 ENST00000602735.1
 IFITM3
 interferon induced transmembrane protein 3
chr14_+_101123580 0.02 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
 LINC00523
 long intergenic non-protein coding RNA 523
chr1_+_174670143 0.02 ENST00000367687.1
ENST00000347255.2
 RABGAP1L
 RAB GTPase activating protein 1-like
chr2_-_127977654 0.02 ENST00000409327.1
 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
chr6_+_116937636 0.02 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
 RSPH4A
 radial spoke head 4 homolog A (Chlamydomonas)
chr22_+_25202232 0.02 ENST00000400358.4
ENST00000400359.4
 SGSM1
 small G protein signaling modulator 1
chr16_+_72088376 0.02 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
 HP
HPR
 haptoglobin
haptoglobin-related protein
chr6_+_26104104 0.02 ENST00000377803.2
 HIST1H4C
 histone cluster 1, H4c
chr1_-_198990166 0.02 ENST00000427439.1
 RP11-16L9.3
 RP11-16L9.3
chr12_+_12224331 0.02 ENST00000396367.1
ENST00000266434.4
ENST00000396369.1
 BCL2L14
 BCL2-like 14 (apoptosis facilitator)
chr10_-_46030787 0.01 ENST00000395769.2
 MARCH8
 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr16_-_28503327 0.01 ENST00000535392.1
ENST00000395653.4
 CLN3
 ceroid-lipofuscinosis, neuronal 3
chr20_+_54823788 0.01 ENST00000243911.2
 MC3R
 melanocortin 3 receptor
chr19_+_45417812 0.01 ENST00000592535.1
 APOC1
 apolipoprotein C-I
chr14_-_106668095 0.00 ENST00000390606.2
 IGHV3-20
 immunoglobulin heavy variable 3-20
chr21_-_44495964 0.00 ENST00000398168.1
ENST00000398165.3
 CBS
 cystathionine-beta-synthase
chr1_-_52344471 0.00 ENST00000352171.7
ENST00000354831.7
 NRD1
 nardilysin (N-arginine dibasic convertase)
chr2_-_198540719 0.00 ENST00000295049.4
 RFTN2
 raftlin family member 2
chr16_+_75182376 0.00 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
 ZFP1
 ZFP1 zinc finger protein
chr10_+_82300575 0.00 ENST00000313455.4
 SH2D4B
 SH2 domain containing 4B
chr14_-_75330537 0.00 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
 PROX2
 prospero homeobox 2
chr2_-_89568263 0.00 ENST00000473726.1
 IGKV1-33
 immunoglobulin kappa variable 1-33
chr1_-_161208013 0.00 ENST00000515452.1
ENST00000367983.4
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr1_-_154600421 0.00 ENST00000368471.3
ENST00000292205.5
 ADAR
 adenosine deaminase, RNA-specific
chr17_+_34171081 0.00 ENST00000585577.1
 TAF15
 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.4 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.5 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.6 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.4 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.9 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 1.0 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.0 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.0 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 2.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.4 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.0 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis