Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
ATF6 Links Ensembl NCBI GeneCards UniProt	ENSG00000118217.5	ATF6

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ATF6	hg19_v2_chr1_+_161736072_161736093	-0.51	2.0e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr3_+_45067659	2.47	ENST00000296130.4	CLEC3B	C-type lectin domain family 3, member B
chr4_+_145567173	2.31	ENST00000296575.3	HHIP	hedgehog interacting protein
chr11_-_35547572	2.22	ENST00000378880.2	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr11_+_113930291	2.10	ENST00000335953.4	ZBTB16	zinc finger and BTB domain containing 16
chr11_-_35547151	2.09	ENST00000378878.3 ENST00000529303.1 ENST00000278360.3	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr9_-_79520989	2.04	ENST00000376713.3 ENST00000376718.3 ENST00000428286.1	PRUNE2	prune homolog 2 (Drosophila)
chr20_-_34042558	1.95	ENST00000374372.1	GDF5	growth differentiation factor 5
chr5_+_156712372	1.86	ENST00000541131.1	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr4_+_145567297	1.83	ENST00000434550.2	HHIP	hedgehog interacting protein
chr17_-_66951474	1.79	ENST00000269080.2	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr9_+_91606355	1.67	ENST00000358157.2	S1PR3	sphingosine-1-phosphate receptor 3
chr22_+_38864041	1.67	ENST00000216014.4 ENST00000409006.3	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_-_39640513	1.46	ENST00000511809.1 ENST00000505729.1	SMIM14	small integral membrane protein 14
chr22_-_20850128	1.46	ENST00000328879.4	KLHL22	kelch-like family member 22
chr14_+_96505659	1.40	ENST00000555004.1	C14orf132	chromosome 14 open reading frame 132
chr7_-_19157248	1.32	ENST00000242261.5	TWIST1	twist family bHLH transcription factor 1
chr4_-_39640700	1.29	ENST00000295958.5	SMIM14	small integral membrane protein 14
chr8_+_97657449	1.13	ENST00000220763.5	CPQ	carboxypeptidase Q
chr12_+_117176090	1.11	ENST00000257575.4 ENST00000407967.3 ENST00000392549.2	RNFT2	ring finger protein, transmembrane 2
chr1_+_221051699	1.05	ENST00000366903.6	HLX	H2.0-like homeobox
chrX_-_101397433	1.03	ENST00000372774.3	TCEAL6	transcription elongation factor A (SII)-like 6
chr5_-_132299290	1.00	ENST00000378595.3	AFF4	AF4/FMR2 family, member 4
chr9_+_36036430	0.96	ENST00000377966.3	RECK	reversion-inducing-cysteine-rich protein with kazal motifs
chr13_-_49107303	0.96	ENST00000344532.3	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr9_-_89562104	0.92	ENST00000298743.7	GAS1	growth arrest-specific 1
chrX_+_102862834	0.90	ENST00000372627.5 ENST00000243286.3	TCEAL3	transcription elongation factor A (SII)-like 3
chr19_+_49458107	0.89	ENST00000539787.1 ENST00000345358.7 ENST00000391871.3 ENST00000415969.2 ENST00000354470.3 ENST00000506183.1 ENST00000293288.8	BAX	BCL2-associated X protein
chr16_-_73082274	0.88	ENST00000268489.5	ZFHX3	zinc finger homeobox 3
chr19_+_35630628	0.88	ENST00000588715.1 ENST00000588607.1	FXYD1	FXYD domain containing ion transport regulator 1
chr16_+_53164833	0.86	ENST00000564845.1	CHD9	chromodomain helicase DNA binding protein 9
chr12_+_117176113	0.85	ENST00000319176.7	RNFT2	ring finger protein, transmembrane 2
chr19_+_10527449	0.85	ENST00000592685.1 ENST00000380702.2	PDE4A	phosphodiesterase 4A, cAMP-specific
chr19_+_35630926	0.82	ENST00000588081.1 ENST00000589121.1	FXYD1	FXYD domain containing ion transport regulator 1
chr21_+_38445539	0.81	ENST00000418766.1 ENST00000450533.1 ENST00000438055.1 ENST00000355666.1 ENST00000540756.1 ENST00000399010.1	TTC3	tetratricopeptide repeat domain 3
chr12_-_76953453	0.81	ENST00000549570.1	OSBPL8	oxysterol binding protein-like 8
chr7_+_102073966	0.77	ENST00000495936.1 ENST00000356387.2 ENST00000478730.2 ENST00000468241.1 ENST00000403646.3	ORAI2	ORAI calcium release-activated calcium modulator 2
chr6_-_25042231	0.71	ENST00000510784.2	FAM65B	family with sequence similarity 65, member B
chr22_-_31741757	0.70	ENST00000215919.3	PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr14_-_23822080	0.67	ENST00000397267.1 ENST00000354772.3	SLC22A17	solute carrier family 22, member 17
chr12_+_1100449	0.67	ENST00000360905.4	ERC1	ELKS/RAB6-interacting/CAST family member 1
chr6_+_132891461	0.67	ENST00000275198.1	TAAR6	trace amine associated receptor 6
chr14_-_23822061	0.67	ENST00000397260.3	SLC22A17	solute carrier family 22, member 17
chr7_-_98467629	0.66	ENST00000339375.4	TMEM130	transmembrane protein 130
chrX_+_153672468	0.64	ENST00000393600.3	FAM50A	family with sequence similarity 50, member A
chr7_-_98467543	0.64	ENST00000345589.4	TMEM130	transmembrane protein 130
chr7_-_8302207	0.64	ENST00000407906.1	ICA1	islet cell autoantigen 1, 69kDa
chr7_-_98467489	0.62	ENST00000416379.2	TMEM130	transmembrane protein 130
chr1_-_15850676	0.62	ENST00000440484.1 ENST00000333868.5	CASP9	caspase 9, apoptosis-related cysteine peptidase
chr12_+_56661033	0.62	ENST00000433805.2	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr20_+_34043085	0.62	ENST00000397527.1 ENST00000342580.4	CEP250	centrosomal protein 250kDa
chr3_+_129159039	0.60	ENST00000507564.1 ENST00000431818.2 ENST00000504021.1 ENST00000349441.2 ENST00000348417.2 ENST00000440957.2	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr8_+_22422749	0.59	ENST00000523900.1	SORBS3	sorbin and SH3 domain containing 3
chr3_+_129158926	0.59	ENST00000347300.2 ENST00000296266.3	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr1_-_15850839	0.57	ENST00000348549.5 ENST00000546424.1	CASP9	caspase 9, apoptosis-related cysteine peptidase
chr12_-_110011288	0.57	ENST00000540016.1 ENST00000266839.5	MMAB	methylmalonic aciduria (cobalamin deficiency) cblB type
chr20_-_34638841	0.56	ENST00000565493.1	LINC00657	long intergenic non-protein coding RNA 657
chrX_-_100872911	0.55	ENST00000361910.4 ENST00000539247.1 ENST00000538627.1	ARMCX6	armadillo repeat containing, X-linked 6
chr12_+_56660633	0.55	ENST00000308197.5	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr5_+_126112794	0.53	ENST00000261366.5 ENST00000395354.1	LMNB1	lamin B1
chr5_-_131562935	0.53	ENST00000379104.2 ENST00000379100.2 ENST00000428369.1	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr12_+_72148614	0.52	ENST00000261263.3	RAB21	RAB21, member RAS oncogene family
chr15_+_67420441	0.51	ENST00000558894.1	SMAD3	SMAD family member 3
chr22_-_20850070	0.51	ENST00000440659.2 ENST00000458248.1 ENST00000443285.1 ENST00000444967.1 ENST00000451553.1 ENST00000431430.1	KLHL22	kelch-like family member 22
chr15_+_41913690	0.50	ENST00000563576.1	MGA	MGA, MAX dimerization protein
chr8_+_22423219	0.49	ENST00000523965.1 ENST00000521554.1	SORBS3	sorbin and SH3 domain containing 3
chr13_+_114238997	0.48	ENST00000538138.1 ENST00000375370.5	TFDP1	transcription factor Dp-1
chr20_-_2821756	0.47	ENST00000356872.3 ENST00000439542.1	PCED1A	PC-esterase domain containing 1A
chr20_-_2821271	0.46	ENST00000448755.1 ENST00000360652.2	PCED1A	PC-esterase domain containing 1A
chr9_+_112542572	0.46	ENST00000374530.3	PALM2-AKAP2	PALM2-AKAP2 readthrough
chr16_+_29973351	0.45	ENST00000602948.1 ENST00000279396.6 ENST00000575829.2 ENST00000561899.2	TMEM219	transmembrane protein 219
chr10_-_118032979	0.44	ENST00000355422.6	GFRA1	GDNF family receptor alpha 1
chr22_-_36903101	0.44	ENST00000397224.4	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr7_-_100493744	0.44	ENST00000428317.1 ENST00000441605.1	ACHE	acetylcholinesterase (Yt blood group)
chr11_-_77791156	0.43	ENST00000281031.4	NDUFC2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr1_+_114472481	0.43	ENST00000369555.2	HIPK1	homeodomain interacting protein kinase 1
chrX_+_48433326	0.43	ENST00000376755.1	RBM3	RNA binding motif (RNP1, RRM) protein 3
chr6_-_24489842	0.43	ENST00000230036.1	GPLD1	glycosylphosphatidylinositol specific phospholipase D1
chr19_-_18391708	0.42	ENST00000600972.1	JUND	jun D proto-oncogene
chr12_-_56123444	0.42	ENST00000546457.1 ENST00000549117.1	CD63	CD63 molecule
chr1_-_208417620	0.42	ENST00000367033.3	PLXNA2	plexin A2
chr14_-_35183755	0.41	ENST00000555765.1	CFL2	cofilin 2 (muscle)
chr17_+_66511540	0.41	ENST00000588188.2	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_-_169931231	0.41	ENST00000504561.1	CBR4	carbonyl reductase 4
chr10_+_35416090	0.41	ENST00000354759.3	CREM	cAMP responsive element modulator
chr14_-_35183886	0.40	ENST00000298159.6	CFL2	cofilin 2 (muscle)
chr20_+_39657454	0.40	ENST00000361337.2	TOP1	topoisomerase (DNA) I
chr20_+_56964169	0.40	ENST00000475243.1	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr16_-_54320675	0.40	ENST00000329734.3	IRX3	iroquois homeobox 3
chr4_-_119757239	0.40	ENST00000280551.6	SEC24D	SEC24 family member D
chr17_+_65821636	0.40	ENST00000544778.2	BPTF	bromodomain PHD finger transcription factor
chr6_+_132873832	0.39	ENST00000275200.1	TAAR8	trace amine associated receptor 8
chr15_+_96869165	0.39	ENST00000421109.2	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr15_-_40213080	0.39	ENST00000561100.1	GPR176	G protein-coupled receptor 176
chr12_+_1100370	0.39	ENST00000543086.3 ENST00000546231.2 ENST00000397203.2	ERC1	ELKS/RAB6-interacting/CAST family member 1
chr20_+_37590942	0.39	ENST00000373325.2 ENST00000252011.3 ENST00000373323.4	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr3_+_170075436	0.39	ENST00000476188.1 ENST00000259119.4 ENST00000426052.2	SKIL	SKI-like oncogene
chr6_+_127588020	0.39	ENST00000309649.3 ENST00000610162.1 ENST00000610153.1 ENST00000608991.1 ENST00000480444.1	RNF146	ring finger protein 146
chr1_-_25573937	0.39	ENST00000417642.2 ENST00000431849.2	C1orf63	chromosome 1 open reading frame 63
chr3_-_101395936	0.39	ENST00000461821.1	ZBTB11	zinc finger and BTB domain containing 11
chr1_-_160313025	0.38	ENST00000368069.3 ENST00000241704.7	COPA	coatomer protein complex, subunit alpha
chr12_-_76953513	0.38	ENST00000547540.1	OSBPL8	oxysterol binding protein-like 8
chr5_-_64777733	0.38	ENST00000381055.3	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr19_+_16186903	0.38	ENST00000588507.1	TPM4	tropomyosin 4
chr1_-_25573977	0.38	ENST00000243189.7	C1orf63	chromosome 1 open reading frame 63
chrX_+_102631844	0.38	ENST00000372634.1 ENST00000299872.7	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr10_+_35415719	0.38	ENST00000474362.1 ENST00000374721.3	CREM	cAMP responsive element modulator
chr10_-_104953009	0.37	ENST00000470299.1 ENST00000343289.5	NT5C2	5'-nucleotidase, cytosolic II
chrX_+_102631248	0.37	ENST00000361298.4 ENST00000372645.3 ENST00000372635.1	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr4_+_668348	0.37	ENST00000511290.1	MYL5	myosin, light chain 5, regulatory
chr14_+_55518349	0.36	ENST00000395468.4	MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like
chr5_+_133984462	0.35	ENST00000398844.2 ENST00000322887.4	SEC24A	SEC24 family member A
chr5_-_171881491	0.35	ENST00000311601.5	SH3PXD2B	SH3 and PX domains 2B
chr1_-_51425902	0.35	ENST00000396153.2	FAF1	Fas (TNFRSF6) associated factor 1
chr1_+_197170592	0.35	ENST00000535699.1	CRB1	crumbs homolog 1 (Drosophila)
chr17_+_4046462	0.34	ENST00000577075.2 ENST00000575251.1 ENST00000301391.3	CYB5D2	cytochrome b5 domain containing 2
chr7_+_100464760	0.34	ENST00000200457.4	TRIP6	thyroid hormone receptor interactor 6
chr3_+_3168692	0.34	ENST00000402675.1 ENST00000413000.1	TRNT1	tRNA nucleotidyl transferase, CCA-adding, 1
chrX_-_102941596	0.33	ENST00000441076.2 ENST00000422355.1 ENST00000442614.1 ENST00000422154.2 ENST00000451301.1	MORF4L2	mortality factor 4 like 2
chr2_+_242254507	0.33	ENST00000391973.2	SEPT2	septin 2
chr3_+_44771088	0.33	ENST00000396048.2	ZNF501	zinc finger protein 501
chr20_-_42815733	0.33	ENST00000342272.3	JPH2	junctophilin 2
chr6_+_127587755	0.33	ENST00000368314.1 ENST00000476956.1 ENST00000609447.1 ENST00000356799.2 ENST00000477776.1 ENST00000609944.1	RNF146	ring finger protein 146
chr6_-_90062543	0.33	ENST00000435041.2	UBE2J1	ubiquitin-conjugating enzyme E2, J1
chr6_+_33168637	0.33	ENST00000374677.3	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr12_-_102455846	0.32	ENST00000545679.1	CCDC53	coiled-coil domain containing 53
chr12_-_102455902	0.32	ENST00000240079.6	CCDC53	coiled-coil domain containing 53
chr15_-_43785274	0.32	ENST00000413546.1	TP53BP1	tumor protein p53 binding protein 1
chr6_+_33168597	0.31	ENST00000374675.3	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr7_+_99102267	0.31	ENST00000326775.5 ENST00000451158.1	ZKSCAN5	zinc finger with KRAB and SCAN domains 5
chr12_-_10766184	0.31	ENST00000539554.1 ENST00000381881.2 ENST00000320756.2	MAGOHB	mago-nashi homolog B (Drosophila)
chr17_-_57184260	0.30	ENST00000376149.3 ENST00000393066.3	TRIM37	tripartite motif containing 37
chr2_-_27712583	0.30	ENST00000260570.3 ENST00000359466.6 ENST00000416524.2	IFT172	intraflagellar transport 172 homolog (Chlamydomonas)
chrX_+_108780347	0.30	ENST00000372103.1	NXT2	nuclear transport factor 2-like export factor 2
chr12_+_113796347	0.30	ENST00000545182.2 ENST00000280800.3	PLBD2	phospholipase B domain containing 2
chr8_-_38126635	0.30	ENST00000529359.1	PPAPDC1B	phosphatidic acid phosphatase type 2 domain containing 1B
chr6_+_29624898	0.30	ENST00000396704.3 ENST00000483013.1 ENST00000490427.1 ENST00000416766.2 ENST00000376891.4 ENST00000376898.3 ENST00000396701.2 ENST00000494692.1 ENST00000431798.2	MOG	myelin oligodendrocyte glycoprotein
chr5_-_131563501	0.29	ENST00000401867.1 ENST00000379086.1 ENST00000418055.1 ENST00000453286.1 ENST00000166534.4	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr15_-_50978965	0.29	ENST00000560955.1 ENST00000313478.7	TRPM7	transient receptor potential cation channel, subfamily M, member 7
chr15_+_76135622	0.29	ENST00000338677.4 ENST00000267938.4 ENST00000569423.1	UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2
chr6_-_84937314	0.29	ENST00000257766.4 ENST00000403245.3	KIAA1009	KIAA1009
chr8_-_38126675	0.29	ENST00000531823.1 ENST00000534339.1 ENST00000524616.1 ENST00000422581.2 ENST00000424479.2 ENST00000419686.2	PPAPDC1B	phosphatidic acid phosphatase type 2 domain containing 1B
chrX_+_134478706	0.29	ENST00000370761.3 ENST00000339249.4 ENST00000370760.3	ZNF449	zinc finger protein 449
chr2_-_242212227	0.29	ENST00000427007.1 ENST00000458564.1 ENST00000452065.1 ENST00000427183.2 ENST00000426343.1 ENST00000422080.1 ENST00000449504.1 ENST00000449864.1 ENST00000391975.1	HDLBP	high density lipoprotein binding protein
chr7_-_27169801	0.28	ENST00000511914.1	HOXA4	homeobox A4
chr9_+_100000717	0.28	ENST00000375205.2 ENST00000357054.1 ENST00000395220.1 ENST00000375202.2 ENST00000411667.2	CCDC180	coiled-coil domain containing 180
chr6_+_29624758	0.28	ENST00000376917.3 ENST00000376902.3 ENST00000533330.2 ENST00000376888.2	MOG	myelin oligodendrocyte glycoprotein
chr19_+_5904866	0.27	ENST00000339485.3	VMAC	vimentin-type intermediate filament associated coiled-coil protein
chr10_-_31320840	0.27	ENST00000375311.1	ZNF438	zinc finger protein 438
chr2_-_10588630	0.27	ENST00000234111.4	ODC1	ornithine decarboxylase 1
chr20_+_44421137	0.27	ENST00000415790.1	DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1
chr10_+_35415978	0.27	ENST00000429130.3 ENST00000469949.2 ENST00000460270.1	CREM	cAMP responsive element modulator
chr12_-_76953573	0.27	ENST00000549646.1 ENST00000550628.1 ENST00000553139.1 ENST00000261183.3 ENST00000393250.4	OSBPL8	oxysterol binding protein-like 8
chr12_+_54718904	0.27	ENST00000262061.2 ENST00000549043.1 ENST00000552218.1 ENST00000553231.1 ENST00000552362.1 ENST00000455864.2 ENST00000416254.2 ENST00000549116.1 ENST00000551779.1	COPZ1	coatomer protein complex, subunit zeta 1
chr1_+_32645269	0.26	ENST00000373610.3	TXLNA	taxilin alpha
chr11_+_120195992	0.26	ENST00000314475.2 ENST00000529187.1	TMEM136	transmembrane protein 136
chr14_+_50087468	0.26	ENST00000305386.2	MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr9_+_99212403	0.26	ENST00000375251.3 ENST00000375249.4	HABP4	hyaluronan binding protein 4
chr20_+_2821340	0.26	ENST00000380445.3 ENST00000380469.3	VPS16	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr1_-_145039949	0.26	ENST00000313382.9	PDE4DIP	phosphodiesterase 4D interacting protein
chr11_+_1891380	0.26	ENST00000429923.1 ENST00000418975.1 ENST00000406638.2	LSP1	lymphocyte-specific protein 1
chr9_+_126777676	0.26	ENST00000488674.2	LHX2	LIM homeobox 2
chr7_+_99102573	0.25	ENST00000394170.2	ZKSCAN5	zinc finger with KRAB and SCAN domains 5
chr7_+_97910981	0.25	ENST00000297290.3	BRI3	brain protein I3
chr5_-_114961673	0.25	ENST00000333314.3	TMED7-TICAM2	TMED7-TICAM2 readthrough
chr19_+_13858593	0.25	ENST00000221554.8	CCDC130	coiled-coil domain containing 130
chr11_+_58910295	0.25	ENST00000420244.1	FAM111A	family with sequence similarity 111, member A
chr17_+_57642886	0.25	ENST00000251241.4 ENST00000451169.2 ENST00000425628.3 ENST00000584385.1 ENST00000580030.1	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr12_-_125398602	0.25	ENST00000541272.1 ENST00000535131.1	UBC	ubiquitin C
chr2_-_211036051	0.25	ENST00000418791.1 ENST00000452086.1 ENST00000281772.9	KANSL1L	KAT8 regulatory NSL complex subunit 1-like
chr10_-_22292675	0.24	ENST00000376946.1	DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1
chr19_-_41196534	0.24	ENST00000252891.4	NUMBL	numb homolog (Drosophila)-like
chr20_+_44420617	0.24	ENST00000449078.1 ENST00000456939.1	DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1
chr5_-_132299313	0.24	ENST00000265343.5	AFF4	AF4/FMR2 family, member 4
chr17_+_37026284	0.24	ENST00000433206.2 ENST00000435347.3	LASP1	LIM and SH3 protein 1
chr14_-_77495007	0.24	ENST00000238647.3	IRF2BPL	interferon regulatory factor 2 binding protein-like
chr10_+_35416223	0.24	ENST00000489321.1 ENST00000427847.2 ENST00000345491.3 ENST00000395895.2 ENST00000374728.3 ENST00000487132.1	CREM	cAMP responsive element modulator
chr1_+_26798955	0.24	ENST00000361427.5	HMGN2	high mobility group nucleosomal binding domain 2
chr13_-_36920872	0.24	ENST00000451493.1	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr17_+_33914460	0.24	ENST00000537622.2	AP2B1	adaptor-related protein complex 2, beta 1 subunit
chr5_+_60628074	0.23	ENST00000252744.5	ZSWIM6	zinc finger, SWIM-type containing 6
chr20_+_35090150	0.23	ENST00000340491.4	DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr19_-_48018203	0.23	ENST00000595227.1 ENST00000593761.1 ENST00000263354.3	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr6_+_29624862	0.23	ENST00000376894.4	MOG	myelin oligodendrocyte glycoprotein
chr3_+_50284321	0.23	ENST00000451956.1	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr7_+_99699280	0.23	ENST00000421755.1	AP4M1	adaptor-related protein complex 4, mu 1 subunit
chr5_-_56247935	0.22	ENST00000381199.3 ENST00000381226.3 ENST00000381213.3	MIER3	mesoderm induction early response 1, family member 3
chr11_-_77790865	0.22	ENST00000534029.1 ENST00000525085.1 ENST00000527806.1 ENST00000528164.1 ENST00000528251.1 ENST00000530054.1	NDUFC2 NDUFC2-KCTD14	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa NDUFC2-KCTD14 readthrough
chr5_-_94890648	0.22	ENST00000513823.1 ENST00000514952.1 ENST00000358746.2	TTC37	tetratricopeptide repeat domain 37
chr9_-_124855885	0.22	ENST00000321582.5 ENST00000373776.3	TTLL11	tubulin tyrosine ligase-like family, member 11
chr9_-_127703333	0.22	ENST00000373555.4	GOLGA1	golgin A1
chrX_+_108780062	0.22	ENST00000372106.1	NXT2	nuclear transport factor 2-like export factor 2
chr7_+_97910962	0.22	ENST00000539286.1	BRI3	brain protein I3
chr8_+_22423168	0.22	ENST00000518912.1 ENST00000428103.1	SORBS3	sorbin and SH3 domain containing 3
chr3_+_184529929	0.21	ENST00000287546.4 ENST00000437079.3	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)
chr3_+_184053703	0.21	ENST00000450976.1 ENST00000418281.1 ENST00000340957.5 ENST00000433578.1	FAM131A	family with sequence similarity 131, member A
chr19_-_46088068	0.21	ENST00000263275.4 ENST00000323060.3	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr20_+_44420570	0.21	ENST00000372622.3	DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1
chr17_+_59529743	0.21	ENST00000589003.1 ENST00000393853.4	TBX4	T-box 4
chr9_+_131038425	0.21	ENST00000320188.5 ENST00000608796.1 ENST00000419867.2 ENST00000418976.1	SWI5	SWI5 recombination repair homolog (yeast)
chr3_+_184529948	0.21	ENST00000436792.2 ENST00000446204.2 ENST00000422105.1	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4	2.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.4	2.5	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.3	0.9	GO:1903519	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3	1.2	GO:0035720	intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3	1.7	GO:0010732	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3	2.0	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.3	1.3	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2	0.9	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.2	1.9	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2	1.7	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.2	0.5	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.2	0.6	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1	1.8	GO:0042908	xenobiotic transport(GO:0042908)
0.1	1.8	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.4	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1	0.6	GO:0009236	cobalamin biosynthetic process(GO:0009236)
0.1	0.4	GO:1990180	mitochondrial tRNA 3'-end processing(GO:1990180)
0.1	1.0	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	1.5	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.1	1.0	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.5	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.1	0.4	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1	0.5	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	4.1	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.1	0.4	GO:0072086	specification of loop of Henle identity(GO:0072086)
0.1	0.4	GO:0009956	radial pattern formation(GO:0009956)
0.1	0.3	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.1	0.2	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	0.4	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	1.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.3	GO:0052651	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1	0.2	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
0.1	0.2	GO:0035494	SNARE complex disassembly(GO:0035494)
0.1	1.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	0.2	GO:0003193	pulmonary valve formation(GO:0003193) visceral motor neuron differentiation(GO:0021524) foramen ovale closure(GO:0035922)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.2	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
0.1	0.3	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.2	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.1	0.3	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.1	GO:0039019	pronephric nephron development(GO:0039019)
0.1	0.2	GO:0070842	aggresome assembly(GO:0070842)
0.1	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.8	GO:0030043	actin filament fragmentation(GO:0030043)
0.0	0.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	1.2	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.4	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	1.0	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.5	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	1.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.2	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.2	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.0	0.5	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	2.0	GO:0071173	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.6	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.5	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.2	GO:0021938	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0	0.3	GO:0061525	hindgut development(GO:0061525)
0.0	0.3	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.3	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.4	GO:0044598	polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.4	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.1	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.2	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.4	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.0	0.4	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.2	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	0.4	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:0051013	microtubule severing(GO:0051013)
0.0	0.8	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.4	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0	0.1	GO:0035668	TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0	0.3	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.4	GO:0006937	regulation of muscle contraction(GO:0006937)
0.0	0.1	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.1	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.4	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.1	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.0	0.1	GO:0052422	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) negative regulation by host of symbiont molecular function(GO:0052405) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.0	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0	0.2	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.2	GO:0071907	determination of digestive tract left/right asymmetry(GO:0071907)
0.0	0.2	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	1.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.4	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.7	GO:0006882	cellular zinc ion homeostasis(GO:0006882) zinc II ion transmembrane transport(GO:0071577)
0.0	0.2	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0	1.3	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.0	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0	0.1	GO:1903984	negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.0	GO:0021784	postganglionic parasympathetic fiber development(GO:0021784)
0.0	0.4	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.2	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.0	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0	0.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	1.2	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.9	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.2	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.3	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.6	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.2	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.0	GO:0090156	cellular sphingolipid homeostasis(GO:0090156)
0.0	0.2	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.5	GO:0001652	granular component(GO:0001652)
0.3	1.2	GO:0043293	apoptosome(GO:0043293)
0.2	2.0	GO:0005827	polar microtubule(GO:0005827)
0.1	0.4	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	1.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.3	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.1	1.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	1.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	1.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.5	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.4	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.6	GO:0016589	NURF complex(GO:0016589)
0.1	0.5	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.8	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.2	GO:0055087	Ski complex(GO:0055087)
0.1	0.4	GO:0035976	AP1 complex(GO:0035976)
0.1	0.2	GO:0032798	Swi5-Sfr1 complex(GO:0032798)
0.1	0.2	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	1.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	4.9	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.7	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.4	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.6	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.3	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.5	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.4	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.2	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	0.9	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	2.6	GO:0016605	PML body(GO:0016605)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0042025	host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0	0.5	GO:0035861	site of double-strand break(GO:0035861)
0.0	1.0	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.1	GO:0044423	virion(GO:0019012) virion part(GO:0044423)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	1.7	GO:0030133	transport vesicle(GO:0030133)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.2	1.8	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.2	1.8	GO:0046923	ER retention sequence binding(GO:0046923)
0.2	1.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.2	1.1	GO:0070573	metallodipeptidase activity(GO:0070573)
0.1	2.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.4	GO:0003955	NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1	1.7	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	1.0	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	1.2	GO:0048039	ubiquinone binding(GO:0048039)
0.1	0.4	GO:0033149	FFAT motif binding(GO:0033149)
0.1	1.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.4	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	0.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	1.0	GO:0051434	BH3 domain binding(GO:0051434)
0.1	1.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	1.2	GO:0036122	BMP binding(GO:0036122)
0.1	0.2	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	0.5	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.4	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1	0.2	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1	0.2	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1	0.9	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	1.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.8	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.4	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0004019	adenylosuccinate synthase activity(GO:0004019)
0.0	0.4	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.0	0.1	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.0	0.8	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	1.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	1.9	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	1.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	0.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0052839	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.5	GO:0043274	phospholipase binding(GO:0043274)
0.0	1.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.1	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.0	0.2	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	1.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.8	GO:0030552	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) cAMP binding(GO:0030552)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.0	0.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	1.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.2	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	2.7	GO:0008201	heparin binding(GO:0008201)
0.0	0.6	GO:0004386	helicase activity(GO:0004386)
0.0	0.7	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.8	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	2.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.9	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	1.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID ARF 3PATHWAY	Arf1 pathway
0.0	5.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	3.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.0	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	1.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	3.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation