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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for EGR3_EGR2

Z-value: 0.77

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Transcription factors associated with EGR3_EGR2

Gene Symbol Gene ID Gene Info
ENSG00000179388.8 EGR3
ENSG00000122877.9 EGR2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR3hg19_v2_chr8_-_22550815_225508440.657.8e-02Click!
EGR2hg19_v2_chr10_-_64576105_645761330.432.8e-01Click!

Activity profile of EGR3_EGR2 motif

Sorted Z-values of EGR3_EGR2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_100199800 0.62 ENST00000223061.5
PCOLCE
procollagen C-endopeptidase enhancer
chrX_+_16964794 0.58 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr6_+_72596406 0.55 ENST00000491071.2
RIMS1
regulating synaptic membrane exocytosis 1
chrX_+_16964985 0.51 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr6_+_72596604 0.49 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr18_-_500692 0.48 ENST00000400256.3
COLEC12
collectin sub-family member 12
chr1_+_215256467 0.41 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chrX_-_142722897 0.40 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr20_-_3996165 0.39 ENST00000545616.2
ENST00000358395.6
RNF24
ring finger protein 24
chr7_-_100493482 0.39 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr4_+_145567297 0.38 ENST00000434550.2
HHIP
hedgehog interacting protein
chr13_+_88324870 0.37 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr11_-_2170786 0.35 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_-_66597530 0.35 ENST00000592554.1
FAM20A
family with sequence similarity 20, member A
chr4_+_145567173 0.34 ENST00000296575.3
HHIP
hedgehog interacting protein
chr4_+_150999418 0.34 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr2_-_98612350 0.33 ENST00000186436.5
TMEM131
transmembrane protein 131
chr2_+_148778570 0.33 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr19_+_49617581 0.31 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr12_+_79258444 0.30 ENST00000261205.4
SYT1
synaptotagmin I
chr7_-_100493744 0.29 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr8_+_32406179 0.28 ENST00000405005.3
NRG1
neuregulin 1
chr8_+_32405728 0.28 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1
neuregulin 1
chr12_+_79258547 0.27 ENST00000457153.2
SYT1
synaptotagmin I
chr1_+_114522049 0.26 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr1_+_246887349 0.26 ENST00000366510.3
SCCPDH
saccharopine dehydrogenase (putative)
chr11_+_92702886 0.26 ENST00000257068.2
ENST00000528076.1
MTNR1B
melatonin receptor 1B
chr20_+_37353084 0.25 ENST00000217420.1
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr17_+_72772621 0.25 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104
transmembrane protein 104
chr19_+_49617609 0.25 ENST00000221459.2
ENST00000486217.2
LIN7B
lin-7 homolog B (C. elegans)
chr11_-_65640198 0.25 ENST00000528176.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr8_-_57123815 0.23 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr17_-_1619535 0.23 ENST00000573075.1
ENST00000574306.1
MIR22HG
MIR22 host gene (non-protein coding)
chr19_-_41196534 0.23 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr1_+_183605200 0.23 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_82393052 0.22 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RASGEF1B
RasGEF domain family, member 1B
chr8_+_32405785 0.22 ENST00000287842.3
NRG1
neuregulin 1
chr17_-_1619491 0.21 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG
MIR22 host gene (non-protein coding)
chr9_+_2621798 0.21 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr5_+_40679584 0.21 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr5_-_178054014 0.21 ENST00000520957.1
CLK4
CDC-like kinase 4
chr8_+_57124245 0.21 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_-_36246060 0.21 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_-_13043697 0.21 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr19_-_54693521 0.21 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr6_+_47624172 0.20 ENST00000507065.1
ENST00000296862.1
GPR111
G protein-coupled receptor 111
chr2_-_38830030 0.20 ENST00000410076.1
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr19_-_41196458 0.20 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr3_+_149689066 0.20 ENST00000593416.1
AC117395.1
LOC646903 protein; Uncharacterized protein
chr19_-_51472031 0.20 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr20_-_3996036 0.19 ENST00000336095.6
RNF24
ring finger protein 24
chr4_-_175443943 0.19 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr19_-_15311713 0.19 ENST00000601011.1
ENST00000263388.2
NOTCH3
notch 3
chr3_+_134514093 0.19 ENST00000398015.3
EPHB1
EPH receptor B1
chr7_-_127032363 0.19 ENST00000393312.1
ZNF800
zinc finger protein 800
chr5_+_67584174 0.18 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_-_47479246 0.18 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr19_-_51472222 0.18 ENST00000376851.3
KLK6
kallikrein-related peptidase 6
chr1_+_9648921 0.18 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201
transmembrane protein 201
chr15_+_43809797 0.18 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr1_-_33647267 0.17 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr16_-_850723 0.17 ENST00000248150.4
GNG13
guanine nucleotide binding protein (G protein), gamma 13
chr11_+_64009072 0.17 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr3_+_3168692 0.17 ENST00000402675.1
ENST00000413000.1
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr17_-_79008373 0.17 ENST00000577066.1
ENST00000573167.1
BAIAP2-AS1
BAIAP2 antisense RNA 1 (head to head)
chrX_+_133930798 0.16 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr1_+_159141397 0.16 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr9_+_2622085 0.16 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr20_-_61569227 0.16 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
DIDO1
death inducer-obliterator 1
chr2_+_202899310 0.16 ENST00000286201.1
FZD7
frizzled family receptor 7
chrX_-_112084043 0.16 ENST00000304758.1
AMOT
angiomotin
chrX_+_117957741 0.16 ENST00000310164.2
ZCCHC12
zinc finger, CCHC domain containing 12
chr8_-_110704014 0.16 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU
syntabulin (syntaxin-interacting)
chr8_+_38644715 0.16 ENST00000317827.4
ENST00000379931.3
TACC1
transforming, acidic coiled-coil containing protein 1
chr9_-_131709858 0.16 ENST00000372586.3
DOLK
dolichol kinase
chr3_+_101546827 0.15 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_+_46316677 0.15 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr10_-_27444143 0.15 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr7_-_108096765 0.15 ENST00000379024.4
ENST00000351718.4
NRCAM
neuronal cell adhesion molecule
chr4_-_119274121 0.15 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr20_+_34129770 0.15 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3
ERGIC and golgi 3
chr10_-_129924611 0.15 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr15_-_71146460 0.15 ENST00000344870.4
LARP6
La ribonucleoprotein domain family, member 6
chr19_+_39786962 0.15 ENST00000333625.2
IFNL1
interferon, lambda 1
chr8_+_32406137 0.15 ENST00000521670.1
NRG1
neuregulin 1
chr3_-_136471204 0.14 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr9_+_37650945 0.14 ENST00000377765.3
FRMPD1
FERM and PDZ domain containing 1
chr2_-_220083671 0.14 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_220083692 0.14 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr8_-_110703819 0.14 ENST00000532779.1
ENST00000534578.1
SYBU
syntabulin (syntaxin-interacting)
chr1_-_160040038 0.14 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr5_+_149569520 0.14 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr8_-_27469196 0.14 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr12_-_42983478 0.14 ENST00000345127.3
ENST00000547113.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr7_-_108096822 0.14 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr1_+_51434357 0.14 ENST00000396148.1
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr4_-_175443788 0.14 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr2_-_219433014 0.14 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr4_-_175443484 0.14 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr9_-_130517522 0.13 ENST00000373274.3
ENST00000420366.1
SH2D3C
SH2 domain containing 3C
chr8_+_145691411 0.13 ENST00000301332.2
KIFC2
kinesin family member C2
chr19_+_44037334 0.13 ENST00000314228.5
ZNF575
zinc finger protein 575
chr2_+_61108771 0.13 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr12_+_49372251 0.13 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr16_+_29690358 0.13 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr5_-_9546180 0.13 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr2_-_220083076 0.13 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr9_-_33264557 0.13 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr17_+_30593195 0.13 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr15_-_83316254 0.13 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr7_+_100770328 0.13 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr3_+_197518100 0.13 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr19_+_18111927 0.13 ENST00000379656.3
ARRDC2
arrestin domain containing 2
chr16_+_2588012 0.12 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr15_+_91446157 0.12 ENST00000559717.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr5_-_141030943 0.12 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr11_+_43964055 0.12 ENST00000528572.1
C11orf96
chromosome 11 open reading frame 96
chr19_-_36523709 0.12 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr11_+_20044600 0.12 ENST00000311043.8
NAV2
neuron navigator 2
chr2_-_158732340 0.12 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr15_-_41408339 0.12 ENST00000401393.3
INO80
INO80 complex subunit
chr10_-_62761188 0.12 ENST00000357917.4
RHOBTB1
Rho-related BTB domain containing 1
chr19_+_35168633 0.12 ENST00000505365.2
ZNF302
zinc finger protein 302
chrX_+_153686614 0.12 ENST00000369682.3
PLXNA3
plexin A3
chr10_+_105036909 0.12 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr1_-_37499726 0.12 ENST00000373091.3
ENST00000373093.4
GRIK3
glutamate receptor, ionotropic, kainate 3
chrX_-_19905703 0.12 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr10_+_131265443 0.12 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr21_-_28338732 0.12 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_+_69002052 0.12 ENST00000497079.1
ARHGAP25
Rho GTPase activating protein 25
chr5_-_172662303 0.12 ENST00000517440.1
ENST00000329198.4
NKX2-5
NK2 homeobox 5
chr6_+_31865552 0.12 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr16_+_2587965 0.12 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_-_97405775 0.11 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr7_+_95401851 0.11 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr16_+_53164833 0.11 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr16_+_2198604 0.11 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr19_+_55795493 0.11 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr9_-_113800317 0.11 ENST00000374431.3
LPAR1
lysophosphatidic acid receptor 1
chr11_+_66059339 0.11 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr16_-_2185899 0.11 ENST00000262304.4
ENST00000423118.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr15_+_76629064 0.11 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr1_+_65886262 0.11 ENST00000371065.4
LEPROT
leptin receptor overlapping transcript
chr15_-_75744014 0.11 ENST00000394947.3
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr1_-_38512450 0.11 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr12_-_57634475 0.11 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr15_-_93632421 0.11 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr1_+_107683436 0.11 ENST00000370068.1
NTNG1
netrin G1
chr11_-_65548265 0.11 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr3_-_169487617 0.11 ENST00000330368.2
ACTRT3
actin-related protein T3
chr15_-_75743991 0.11 ENST00000567289.1
SIN3A
SIN3 transcription regulator family member A
chr16_-_2264779 0.11 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr19_-_40724246 0.11 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr17_+_48796905 0.11 ENST00000505658.1
ENST00000393227.2
ENST00000240304.1
ENST00000311571.3
ENST00000505619.1
ENST00000544170.1
ENST00000510984.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr4_-_83351294 0.11 ENST00000502762.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr5_-_33892046 0.11 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr3_-_9994021 0.11 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr15_+_32322685 0.11 ENST00000454250.3
ENST00000306901.3
CHRNA7
cholinergic receptor, nicotinic, alpha 7 (neuronal)
chr6_-_137113604 0.10 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr10_-_64028466 0.10 ENST00000395265.1
ENST00000373789.3
ENST00000395260.3
RTKN2
rhotekin 2
chr17_+_59477233 0.10 ENST00000240328.3
TBX2
T-box 2
chr4_-_57976544 0.10 ENST00000295666.4
ENST00000537922.1
IGFBP7
insulin-like growth factor binding protein 7
chr16_+_2587998 0.10 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr17_-_62502399 0.10 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr22_+_37956453 0.10 ENST00000249014.4
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr11_+_117198801 0.10 ENST00000527609.1
ENST00000533570.1
CEP164
centrosomal protein 164kDa
chr16_+_69140122 0.10 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr19_+_35168567 0.10 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr9_-_132515302 0.10 ENST00000340607.4
PTGES
prostaglandin E synthase
chr20_+_53092123 0.10 ENST00000262593.5
DOK5
docking protein 5
chr2_+_121103706 0.10 ENST00000295228.3
INHBB
inhibin, beta B
chr5_+_67511524 0.10 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr15_+_32322709 0.10 ENST00000455693.2
CHRNA7
cholinergic receptor, nicotinic, alpha 7 (neuronal)
chr5_-_178054105 0.10 ENST00000316308.4
CLK4
CDC-like kinase 4
chr20_+_34894247 0.10 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr3_-_88108212 0.10 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr6_+_30524663 0.10 ENST00000376560.3
PRR3
proline rich 3
chr15_-_27184664 0.10 ENST00000541819.2
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr22_+_45898712 0.10 ENST00000455233.1
ENST00000348697.2
ENST00000402984.3
ENST00000262722.7
ENST00000327858.6
ENST00000442170.2
ENST00000340923.5
ENST00000439835.1
FBLN1
fibulin 1
chr3_-_87040233 0.10 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr8_-_27468945 0.10 ENST00000405140.3
CLU
clusterin
chr19_-_16682987 0.10 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1
solute carrier family 35, member E1
chr13_-_110959478 0.10 ENST00000543140.1
ENST00000375820.4
COL4A1
collagen, type IV, alpha 1
chr17_-_62502022 0.10 ENST00000578804.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr3_-_124774802 0.10 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr14_-_74417096 0.10 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr1_-_160001737 0.10 ENST00000368090.2
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr2_+_191745535 0.10 ENST00000320717.3
GLS
glutaminase
chr1_+_236305826 0.09 ENST00000366592.3
ENST00000366591.4
GPR137B
G protein-coupled receptor 137B
chrX_-_108868390 0.09 ENST00000372101.2
KCNE1L
KCNE1-like
chr5_-_14871866 0.09 ENST00000284268.6
ANKH
ANKH inorganic pyrophosphate transport regulator
chr1_+_178062855 0.09 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr17_+_57697216 0.09 ENST00000393043.1
ENST00000269122.3
CLTC
clathrin, heavy chain (Hc)
chr15_+_41952591 0.09 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr6_-_111804905 0.09 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_-_135056106 0.09 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr5_+_109025067 0.09 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr17_-_62502639 0.09 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr14_+_23352374 0.09 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr14_-_75079026 0.09 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.5 GO:0044691 tooth eruption(GO:0044691)
0.1 0.4 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.2 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.1 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.4 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:1902725 trans-synaptic signaling by trans-synaptic complex(GO:0099545) negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) septum secundum development(GO:0003285)
0.0 0.5 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.1 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0072237 distal tubule morphogenesis(GO:0072156) metanephric proximal tubule development(GO:0072237)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.8 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0015880 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.0 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0061525 hindgut development(GO:0061525)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0061086 regulation of mRNA export from nucleus(GO:0010793) negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.0 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.0 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.0 GO:0030849 Y chromosome(GO:0000806) autosome(GO:0030849)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.0 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0052848 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation