Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
EOMES Links Ensembl NCBI GeneCards UniProt	ENSG00000163508.8	EOMES

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EOMES	hg19_v2_chr3_-_27763803_27763822	0.57	1.4e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr18_-_28681950	0.63	ENST00000251081.6	DSC2	desmocollin 2
chr1_+_70876926	0.34	ENST00000370938.3 ENST00000346806.2	CTH	cystathionase (cystathionine gamma-lyase)
chr1_-_207095324	0.34	ENST00000530505.1 ENST00000367091.3 ENST00000442471.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr2_-_229046361	0.33	ENST00000392056.3	SPHKAP	SPHK1 interactor, AKAP domain containing
chr13_-_20767037	0.33	ENST00000382848.4	GJB2	gap junction protein, beta 2, 26kDa
chr14_+_61995722	0.33	ENST00000556347.1	RP11-47I22.4	RP11-47I22.4
chr2_-_229046330	0.32	ENST00000344657.5	SPHKAP	SPHK1 interactor, AKAP domain containing
chr1_+_60280458	0.32	ENST00000455990.1 ENST00000371208.3	HOOK1	hook microtubule-tethering protein 1
chr1_+_1981890	0.31	ENST00000378567.3 ENST00000468310.1	PRKCZ	protein kinase C, zeta
chr16_-_2031464	0.31	ENST00000356120.4 ENST00000354249.4	NOXO1	NADPH oxidase organizer 1
chr15_+_41136586	0.31	ENST00000431806.1	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr1_+_70876891	0.31	ENST00000411986.2	CTH	cystathionase (cystathionine gamma-lyase)
chr17_+_37784749	0.30	ENST00000394265.1 ENST00000394267.2	PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_+_15256230	0.30	ENST00000376028.4 ENST00000400798.2	KAZN	kazrin, periplakin interacting protein
chr1_-_184943610	0.28	ENST00000367511.3	FAM129A	family with sequence similarity 129, member A
chr20_-_18038521	0.28	ENST00000278780.6	OVOL2	ovo-like zinc finger 2
chr10_+_95653687	0.25	ENST00000371408.3 ENST00000427197.1	SLC35G1	solute carrier family 35, member G1
chr19_-_51456321	0.25	ENST00000391809.2	KLK5	kallikrein-related peptidase 5
chr19_-_51456344	0.25	ENST00000336334.3 ENST00000593428.1	KLK5	kallikrein-related peptidase 5
chr15_+_89182178	0.24	ENST00000559876.1	ISG20	interferon stimulated exonuclease gene 20kDa
chr1_-_207095212	0.24	ENST00000420007.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr1_-_242687989	0.24	ENST00000442594.2	PLD5	phospholipase D family, member 5
chr14_+_21510385	0.24	ENST00000298690.4	RNASE7	ribonuclease, RNase A family, 7
chr5_+_66124590	0.22	ENST00000490016.2 ENST00000403666.1 ENST00000450827.1	MAST4	microtubule associated serine/threonine kinase family member 4
chr10_-_10836865	0.22	ENST00000446372.2	SFTA1P	surfactant associated 1, pseudogene
chr15_+_89182156	0.22	ENST00000379224.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr2_+_95940186	0.20	ENST00000403131.2 ENST00000317668.4 ENST00000317620.9	PROM2	prominin 2
chr21_-_47352477	0.20	ENST00000593412.1	PRED62	Uncharacterized protein
chr1_-_31769656	0.20	ENST00000446633.2	SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)
chr3_+_111805182	0.20	ENST00000430855.1 ENST00000431717.2 ENST00000264848.5	C3orf52	chromosome 3 open reading frame 52
chrX_+_135618258	0.20	ENST00000440515.1 ENST00000456412.1	VGLL1	vestigial like 1 (Drosophila)
chr8_-_9760839	0.20	ENST00000519461.1 ENST00000517675.1	LINC00599	long intergenic non-protein coding RNA 599
chrX_+_51149767	0.19	ENST00000342995.2	CXorf67	chromosome X open reading frame 67
chrX_+_35816908	0.19	ENST00000399985.1	MAGEB16	melanoma antigen family B, 16
chr1_+_14925173	0.18	ENST00000376030.2 ENST00000503743.1 ENST00000422387.2	KAZN	kazrin, periplakin interacting protein
chr15_+_89181974	0.18	ENST00000306072.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr18_-_74839891	0.18	ENST00000581878.1	MBP	myelin basic protein
chr17_+_9548845	0.18	ENST00000570475.1 ENST00000285199.7	USP43	ubiquitin specific peptidase 43
chr12_+_93965609	0.17	ENST00000549887.1 ENST00000551556.1	SOCS2	suppressor of cytokine signaling 2
chr3_-_50649192	0.17	ENST00000443053.2 ENST00000348721.3	CISH	cytokine inducible SH2-containing protein
chr4_-_4291861	0.17	ENST00000343470.4	LYAR	Ly1 antibody reactive
chr4_-_4291761	0.17	ENST00000513174.1	LYAR	Ly1 antibody reactive
chr2_+_220492287	0.17	ENST00000273063.6 ENST00000373762.3	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr4_-_4291748	0.17	ENST00000452476.1	LYAR	Ly1 antibody reactive
chr1_-_31769595	0.16	ENST00000263694.4	SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)
chr19_+_48867652	0.16	ENST00000344846.2	SYNGR4	synaptogyrin 4
chr13_-_102068769	0.16	ENST00000376196.3	NALCN	sodium leak channel, non-selective
chr2_+_220492116	0.16	ENST00000373760.2	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr2_+_220492373	0.16	ENST00000317151.3	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr7_+_94285637	0.16	ENST00000482108.1 ENST00000488574.1	PEG10	paternally expressed 10
chr2_-_235405168	0.16	ENST00000339728.3	ARL4C	ADP-ribosylation factor-like 4C
chr6_+_53659746	0.16	ENST00000370888.1	LRRC1	leucine rich repeat containing 1
chr11_+_117947724	0.16	ENST00000534111.1	TMPRSS4	transmembrane protease, serine 4
chr1_-_109203997	0.15	ENST00000370032.5	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)
chr7_+_16793160	0.15	ENST00000262067.4	TSPAN13	tetraspanin 13
chr14_-_54421190	0.15	ENST00000417573.1	BMP4	bone morphogenetic protein 4
chr11_+_45944190	0.15	ENST00000401752.1 ENST00000389968.3 ENST00000325468.5 ENST00000536139.1	GYLTL1B	glycosyltransferase-like 1B
chr8_+_86089619	0.15	ENST00000256117.5 ENST00000416274.2	E2F5	E2F transcription factor 5, p130-binding
chr2_+_220491973	0.15	ENST00000358055.3	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr11_+_117947782	0.15	ENST00000522307.1 ENST00000523251.1 ENST00000437212.3 ENST00000522824.1 ENST00000522151.1	TMPRSS4	transmembrane protease, serine 4
chr11_-_66139570	0.14	ENST00000311161.7	SLC29A2	solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr15_+_90728145	0.14	ENST00000561085.1 ENST00000379122.3 ENST00000332496.6	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr2_+_95940220	0.14	ENST00000542147.1	PROM2	prominin 2
chr10_-_101190202	0.14	ENST00000543866.1 ENST00000370508.5	GOT1	glutamic-oxaloacetic transaminase 1, soluble
chr22_-_18257178	0.14	ENST00000342111.5	BID	BH3 interacting domain death agonist
chr8_-_124408652	0.14	ENST00000287394.5	ATAD2	ATPase family, AAA domain containing 2
chr1_-_43751230	0.14	ENST00000523677.1	C1orf210	chromosome 1 open reading frame 210
chr17_-_4463856	0.14	ENST00000574584.1 ENST00000381550.3 ENST00000301395.3	GGT6	gamma-glutamyltransferase 6
chr3_+_46283863	0.14	ENST00000545097.1 ENST00000541018.1	CCR3	chemokine (C-C motif) receptor 3
chr8_+_31496809	0.14	ENST00000518104.1 ENST00000519301.1	NRG1	neuregulin 1
chr3_-_128840604	0.13	ENST00000476465.1 ENST00000315150.5 ENST00000393304.1 ENST00000393308.1 ENST00000393307.1 ENST00000393305.1	RAB43	RAB43, member RAS oncogene family
chr3_+_46283916	0.13	ENST00000395940.2	CCR3	chemokine (C-C motif) receptor 3
chrX_+_102469997	0.13	ENST00000372695.5 ENST00000372691.3	BEX4	brain expressed, X-linked 4
chr1_-_109203648	0.13	ENST00000370031.1	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)
chr17_-_74533734	0.13	ENST00000589342.1	CYGB	cytoglobin
chr17_+_73521763	0.12	ENST00000167462.5 ENST00000375227.4 ENST00000392550.3 ENST00000578363.1 ENST00000579392.1	LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr11_+_1860832	0.12	ENST00000252898.7	TNNI2	troponin I type 2 (skeletal, fast)
chr11_+_1860682	0.12	ENST00000381906.1	TNNI2	troponin I type 2 (skeletal, fast)
chr2_-_163175133	0.12	ENST00000421365.2 ENST00000263642.2	IFIH1	interferon induced with helicase C domain 1
chr19_-_14629224	0.12	ENST00000254322.2	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr16_+_202686	0.12	ENST00000252951.2	HBZ	hemoglobin, zeta
chr17_-_4448361	0.12	ENST00000572759.1	MYBBP1A	MYB binding protein (P160) 1a
chr3_-_49893958	0.12	ENST00000482243.1 ENST00000331456.2 ENST00000469027.1	TRAIP	TRAF interacting protein
chr5_-_94620239	0.12	ENST00000515393.1	MCTP1	multiple C2 domains, transmembrane 1
chr10_+_6779326	0.12	ENST00000417112.1	RP11-554I8.2	RP11-554I8.2
chrX_+_48398053	0.12	ENST00000537536.1 ENST00000418627.1	TBC1D25	TBC1 domain family, member 25
chr3_+_50649302	0.12	ENST00000446044.1	MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr14_+_56585048	0.12	ENST00000267460.4	PELI2	pellino E3 ubiquitin protein ligase family member 2
chr8_+_86089460	0.11	ENST00000418930.2	E2F5	E2F transcription factor 5, p130-binding
chr15_-_83953466	0.11	ENST00000345382.2	BNC1	basonuclin 1
chr1_+_150459873	0.11	ENST00000438568.2 ENST00000369054.2 ENST00000369064.3 ENST00000606933.1	TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)
chr6_+_41888926	0.11	ENST00000230340.4	BYSL	bystin-like
chr19_+_33865218	0.11	ENST00000585933.2	CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_160068465	0.11	ENST00000314485.7 ENST00000368086.1	IGSF8	immunoglobulin superfamily, member 8
chr1_-_109203685	0.11	ENST00000402983.1 ENST00000420055.1	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_-_193029192	0.11	ENST00000417752.1 ENST00000367452.4	UCHL5	ubiquitin carboxyl-terminal hydrolase L5
chr4_+_54966198	0.11	ENST00000326902.2 ENST00000503800.1	GSX2	GS homeobox 2
chr3_-_121264848	0.10	ENST00000264233.5	POLQ	polymerase (DNA directed), theta
chr16_-_23568651	0.10	ENST00000563232.1 ENST00000563459.1 ENST00000449606.1	EARS2	glutamyl-tRNA synthetase 2, mitochondrial
chr12_+_121647962	0.10	ENST00000542067.1	P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4
chr4_-_103997455	0.10	ENST00000362026.3 ENST00000503103.1	SLC9B2	solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr14_-_67878917	0.10	ENST00000216446.4	PLEK2	pleckstrin 2
chr5_+_68788594	0.10	ENST00000396442.2 ENST00000380766.2	OCLN	occludin
chr7_-_37024665	0.10	ENST00000396040.2	ELMO1	engulfment and cell motility 1
chr2_-_31637560	0.10	ENST00000379416.3	XDH	xanthine dehydrogenase
chr6_-_163148700	0.10	ENST00000366894.1 ENST00000338468.3	PARK2	parkin RBR E3 ubiquitin protein ligase
chr17_+_4736627	0.10	ENST00000355280.6 ENST00000347992.7	MINK1	misshapen-like kinase 1
chr2_+_230787201	0.09	ENST00000283946.3	FBXO36	F-box protein 36
chr9_+_37485932	0.09	ENST00000377798.4 ENST00000442009.2	POLR1E	polymerase (RNA) I polypeptide E, 53kDa
chr14_+_56584414	0.09	ENST00000559044.1	PELI2	pellino E3 ubiquitin protein ligase family member 2
chr9_-_139137648	0.09	ENST00000358701.5	QSOX2	quiescin Q6 sulfhydryl oxidase 2
chr10_+_104154229	0.09	ENST00000428099.1 ENST00000369966.3	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_54197915	0.09	ENST00000404125.1	PSME4	proteasome (prosome, macropain) activator subunit 4
chr7_+_76109827	0.09	ENST00000446820.2	DTX2	deltex homolog 2 (Drosophila)
chr16_-_75498308	0.09	ENST00000569540.1	TMEM170A	transmembrane protein 170A
chr6_-_73935163	0.09	ENST00000370388.3	KHDC1L	KH homology domain containing 1-like
chr5_-_33892204	0.09	ENST00000504830.1	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr10_-_99393208	0.09	ENST00000307450.6	MORN4	MORN repeat containing 4
chr5_+_149109825	0.09	ENST00000360453.4 ENST00000394320.3 ENST00000309241.5	PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr17_-_17109579	0.09	ENST00000321560.3	PLD6	phospholipase D family, member 6
chrX_+_131157609	0.09	ENST00000496850.1	MST4	Serine/threonine-protein kinase MST4
chr1_+_19578033	0.09	ENST00000330263.4	MRTO4	mRNA turnover 4 homolog (S. cerevisiae)
chr22_+_47070490	0.09	ENST00000408031.1	GRAMD4	GRAM domain containing 4
chr18_+_43753974	0.09	ENST00000282059.6 ENST00000321319.6	C18orf25	chromosome 18 open reading frame 25
chr17_-_42907564	0.09	ENST00000592524.1	GJC1	gap junction protein, gamma 1, 45kDa
chr13_+_25254545	0.09	ENST00000218548.6	ATP12A	ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr8_+_99439214	0.09	ENST00000287042.4	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr17_-_33775760	0.09	ENST00000534689.1 ENST00000532210.1 ENST00000526861.1 ENST00000531588.1 ENST00000285013.6	SLFN13	schlafen family member 13
chr22_-_50913371	0.09	ENST00000348911.6 ENST00000380817.3 ENST00000390679.3	SBF1	SET binding factor 1
chr16_-_69788816	0.09	ENST00000268802.5	NOB1	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr14_-_106622419	0.09	ENST00000390604.2	IGHV3-16	immunoglobulin heavy variable 3-16 (non-functional)
chr5_+_148724993	0.09	ENST00000513661.1 ENST00000329271.3 ENST00000416916.2	GRPEL2	GrpE-like 2, mitochondrial (E. coli)
chr6_-_35888824	0.09	ENST00000361690.3 ENST00000512445.1	SRPK1	SRSF protein kinase 1
chr19_+_51152702	0.09	ENST00000425202.1	C19orf81	chromosome 19 open reading frame 81
chr7_+_136553370	0.09	ENST00000445907.2	CHRM2	cholinergic receptor, muscarinic 2
chr9_+_37486005	0.09	ENST00000377792.3	POLR1E	polymerase (RNA) I polypeptide E, 53kDa
chr2_+_230787213	0.09	ENST00000409992.1	FBXO36	F-box protein 36
chr19_+_19496728	0.08	ENST00000537887.1 ENST00000417582.2	GATAD2A	GATA zinc finger domain containing 2A
chr16_+_15068916	0.08	ENST00000455313.2	PDXDC1	pyridoxal-dependent decarboxylase domain containing 1
chr1_-_205744205	0.08	ENST00000446390.2	RAB7L1	RAB7, member RAS oncogene family-like 1
chr3_+_196466710	0.08	ENST00000327134.3	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chr9_-_136006496	0.08	ENST00000372062.3	RALGDS	ral guanine nucleotide dissociation stimulator
chr1_-_151119087	0.08	ENST00000341697.3 ENST00000368914.3	SEMA6C	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr16_-_75498553	0.08	ENST00000569276.1 ENST00000357613.4 ENST00000561878.1 ENST00000566980.1 ENST00000567194.1	TMEM170A RP11-77K12.1	transmembrane protein 170A Uncharacterized protein
chr17_-_39942940	0.08	ENST00000310706.5 ENST00000393931.3 ENST00000424457.1 ENST00000591690.1	JUP	junction plakoglobin
chr9_+_138235095	0.08	ENST00000320778.2	C9orf62	chromosome 9 open reading frame 62
chr10_+_5454505	0.08	ENST00000355029.4	NET1	neuroepithelial cell transforming 1
chr3_+_38080691	0.08	ENST00000308059.6 ENST00000346219.3 ENST00000452631.2	DLEC1	deleted in lung and esophageal cancer 1
chr18_-_4455260	0.08	ENST00000581527.1	DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chr5_+_61708582	0.08	ENST00000325324.6	IPO11	importin 11
chr1_-_205744574	0.08	ENST00000367139.3 ENST00000235932.4 ENST00000437324.2 ENST00000414729.1	RAB7L1	RAB7, member RAS oncogene family-like 1
chr10_-_99393242	0.08	ENST00000370635.3 ENST00000478953.1 ENST00000335628.3	MORN4	MORN repeat containing 4
chr19_-_48867291	0.08	ENST00000435956.3	TMEM143	transmembrane protein 143
chr15_+_40987327	0.08	ENST00000423169.2 ENST00000267868.3 ENST00000557850.1 ENST00000532743.1 ENST00000382643.3	RAD51	RAD51 recombinase
chr7_-_6010263	0.08	ENST00000455618.2 ENST00000405415.1 ENST00000404406.1 ENST00000542644.1	RSPH10B	radial spoke head 10 homolog B (Chlamydomonas)
chr3_-_127842612	0.08	ENST00000417360.1 ENST00000322623.5	RUVBL1	RuvB-like AAA ATPase 1
chr19_-_48867171	0.08	ENST00000377431.2 ENST00000436660.2 ENST00000541566.1	TMEM143	transmembrane protein 143
chr5_+_56205878	0.08	ENST00000423328.1	SETD9	SET domain containing 9
chr7_+_6793740	0.08	ENST00000403107.1 ENST00000404077.1 ENST00000435395.1 ENST00000418406.1	RSPH10B2	radial spoke head 10 homolog B2 (Chlamydomonas)
chrX_+_131157290	0.08	ENST00000394334.2	MST4	Serine/threonine-protein kinase MST4
chrX_-_54070607	0.07	ENST00000338154.6 ENST00000338946.6	PHF8	PHD finger protein 8
chr2_+_233897382	0.07	ENST00000233840.3	NEU2	sialidase 2 (cytosolic sialidase)
chr3_-_122102065	0.07	ENST00000479899.1 ENST00000291458.5 ENST00000497726.1	CCDC58	coiled-coil domain containing 58
chr10_-_134145321	0.07	ENST00000368625.4 ENST00000368619.3 ENST00000456004.1 ENST00000368620.2	STK32C	serine/threonine kinase 32C
chr14_-_51135036	0.07	ENST00000324679.4	SAV1	salvador homolog 1 (Drosophila)
chr3_+_45986511	0.07	ENST00000458629.1 ENST00000457814.1	CXCR6	chemokine (C-X-C motif) receptor 6
chr3_+_113775576	0.07	ENST00000485050.1 ENST00000281273.4	QTRTD1	queuine tRNA-ribosyltransferase domain containing 1
chr1_-_245027766	0.07	ENST00000283179.9	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_+_125687987	0.07	ENST00000514116.1 ENST00000251776.4 ENST00000504401.1 ENST00000513830.1 ENST00000508088.1	ROPN1B	rhophilin associated tail protein 1B
chr16_-_66959429	0.07	ENST00000420652.1 ENST00000299759.6	RRAD	Ras-related associated with diabetes
chr14_+_32546145	0.07	ENST00000556611.1 ENST00000539826.2	ARHGAP5	Rho GTPase activating protein 5
chr19_-_19384055	0.07	ENST00000389363.4	TM6SF2	transmembrane 6 superfamily member 2
chr3_-_123710893	0.07	ENST00000467907.1 ENST00000459660.1 ENST00000495093.1 ENST00000460743.1 ENST00000405845.3 ENST00000484329.1 ENST00000479867.1 ENST00000496145.1	ROPN1	rhophilin associated tail protein 1
chr14_-_53162361	0.07	ENST00000395686.3	ERO1L	ERO1-like (S. cerevisiae)
chrX_+_131157322	0.07	ENST00000481105.1 ENST00000354719.6 ENST00000394335.2	MST4	Serine/threonine-protein kinase MST4
chr14_+_32546274	0.07	ENST00000396582.2	ARHGAP5	Rho GTPase activating protein 5
chr16_+_31128978	0.07	ENST00000448516.2 ENST00000219797.4	KAT8	K(lysine) acetyltransferase 8
chr1_+_3689325	0.07	ENST00000444870.2 ENST00000452264.1	SMIM1	small integral membrane protein 1 (Vel blood group)
chr1_-_33283754	0.07	ENST00000373477.4	YARS	tyrosyl-tRNA synthetase
chr1_+_46806837	0.07	ENST00000537428.1	NSUN4	NOP2/Sun domain family, member 4
chr22_+_31644388	0.07	ENST00000333611.4 ENST00000340552.4	LIMK2	LIM domain kinase 2
chr6_+_79577189	0.07	ENST00000369940.2	IRAK1BP1	interleukin-1 receptor-associated kinase 1 binding protein 1
chr18_+_77439775	0.07	ENST00000299543.7 ENST00000075430.7	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr3_-_135914615	0.07	ENST00000309993.2	MSL2	male-specific lethal 2 homolog (Drosophila)
chr6_+_168227611	0.07	ENST00000344191.4 ENST00000351017.4 ENST00000392108.3 ENST00000366806.2 ENST00000392112.1 ENST00000400824.4 ENST00000447894.2 ENST00000400822.3	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr11_-_57103327	0.07	ENST00000529002.1 ENST00000278412.2	SSRP1	structure specific recognition protein 1
chr8_-_8318847	0.07	ENST00000521218.1	CTA-398F10.2	CTA-398F10.2
chr16_-_3086927	0.07	ENST00000572449.1	CCDC64B	coiled-coil domain containing 64B
chr19_+_50084561	0.07	ENST00000246794.5	PRRG2	proline rich Gla (G-carboxyglutamic acid) 2
chr3_-_43147431	0.07	ENST00000441964.1	POMGNT2	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr1_-_1149506	0.07	ENST00000379236.3	TNFRSF4	tumor necrosis factor receptor superfamily, member 4
chr1_-_93426998	0.07	ENST00000370310.4	FAM69A	family with sequence similarity 69, member A
chr21_-_47604318	0.07	ENST00000291672.5 ENST00000330205.6	SPATC1L	spermatogenesis and centriole associated 1-like
chr1_-_78444738	0.06	ENST00000436586.2 ENST00000370768.2	FUBP1	far upstream element (FUSE) binding protein 1
chrX_-_72299258	0.06	ENST00000453389.1 ENST00000373519.1	PABPC1L2A	poly(A) binding protein, cytoplasmic 1-like 2A
chr11_+_93861993	0.06	ENST00000227638.3 ENST00000436171.2	PANX1	pannexin 1
chr12_+_65563329	0.06	ENST00000308330.2	LEMD3	LEM domain containing 3
chr18_-_4455283	0.06	ENST00000315677.3	DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chr6_-_163148780	0.06	ENST00000366892.1 ENST00000366898.1 ENST00000366897.1 ENST00000366896.1	PARK2	parkin RBR E3 ubiquitin protein ligase
chr3_-_43147549	0.06	ENST00000344697.2	POMGNT2	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1	0.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.1	0.3	GO:2001287	negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1	0.5	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1	0.3	GO:0044752	response to human chorionic gonadotropin(GO:0044752)
0.1	0.7	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.2	GO:0072097	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0	0.3	GO:0060214	endocardium formation(GO:0060214)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.2	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0	0.3	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0	0.1	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.3	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:2000490	negative regulation of hepatic stellate cell activation(GO:2000490)
0.0	0.3	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.1	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0	0.2	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0	0.2	GO:0051673	membrane disruption in other organism(GO:0051673)
0.0	0.1	GO:0019858	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.1	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0046110	xanthine metabolic process(GO:0046110)
0.0	0.1	GO:1901660	calcium ion export(GO:1901660)
0.0	0.1	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.0	0.1	GO:0046080	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0	0.1	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0	0.5	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0060458	right lung development(GO:0060458)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.1	GO:0060380	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0	0.1	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	0.1	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0	0.1	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0	0.1	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0	0.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0	0.3	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.0	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.0	0.7	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.0	GO:0098838	reduced folate transmembrane transport(GO:0098838)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.3	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.0	GO:1904253	circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0	0.0	GO:0035568	N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.0	GO:1901143	insulin catabolic process(GO:1901143)
0.0	0.1	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0	0.0	GO:0036090	cleavage furrow ingression(GO:0036090)
0.0	0.0	GO:0072709	cellular response to sorbitol(GO:0072709)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.2	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.0	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.1	GO:1903719	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0	0.1	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.0	0.2	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.0	0.0	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.0	GO:0036446	peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0	0.1	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.0	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.2	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	0.3	GO:0044393	microspike(GO:0044393)
0.0	0.3	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0	0.0	GO:0031982	vesicle(GO:0031982)
0.0	1.1	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.1	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.0	0.1	GO:0000229	cytoplasmic chromosome(GO:0000229)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	0.4	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.1	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.4	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.0	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.0	GO:0031021	interphase microtubule organizing center(GO:0031021)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0008859	exoribonuclease II activity(GO:0008859)
0.1	0.3	GO:0031751	D4 dopamine receptor binding(GO:0031751)
0.1	0.7	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.6	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0004818	glutamate-tRNA ligase activity(GO:0004818)
0.0	0.1	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0	0.1	GO:0047888	fatty acid peroxidase activity(GO:0047888)
0.0	0.1	GO:0097363	protein O-GlcNAc transferase activity(GO:0097363)
0.0	0.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.0	0.1	GO:0010348	lithium:proton antiporter activity(GO:0010348)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0	0.5	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.0	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0052871	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.2	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0005174	CD40 receptor binding(GO:0005174)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0032810	sterol response element binding(GO:0032810)
0.0	0.0	GO:0003883	CTP synthase activity(GO:0003883)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0036361	racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.2	GO:0070700	co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.0	0.4	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.0	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat