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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOSB

Z-value: 1.23

Motif logo

Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
ENSG00000125740.9 FOSB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg19_v2_chr19_+_45973120_45973171-0.353.9e-01Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_21452964 7.29 ENST00000587184.1
LAMA3
laminin, alpha 3
chr18_+_21452804 7.06 ENST00000269217.6
LAMA3
laminin, alpha 3
chr19_-_36004543 2.42 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr6_+_125540951 2.14 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr3_-_151034734 2.10 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr11_-_102668879 1.90 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_21059029 1.89 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr11_-_108408895 1.86 ENST00000443411.1
ENST00000533052.1
EXPH5
exophilin 5
chr15_+_40531243 1.79 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr18_+_61442629 1.75 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr15_+_40531621 1.72 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_-_39769005 1.68 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr19_-_35992780 1.59 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr17_-_8021710 1.58 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr11_+_394196 1.50 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr2_+_102618428 1.46 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr16_+_30751953 1.28 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr20_+_44637526 1.27 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr4_-_36246060 1.26 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_-_39264072 1.26 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr19_-_44174330 1.23 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr14_-_94854926 1.23 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_152881014 1.13 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr8_+_120220561 1.13 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr1_-_153029980 1.11 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr5_+_145316120 1.11 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr19_-_44174305 1.08 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr7_-_20256965 1.05 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr5_+_145317356 1.01 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr5_+_66124590 0.99 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_18908040 0.98 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr4_+_84457250 0.98 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr1_+_26869597 0.98 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr3_+_36421826 0.97 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr4_+_84457529 0.96 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr17_+_30771279 0.95 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr4_-_89080003 0.86 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr12_-_95510743 0.86 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr17_-_39942940 0.85 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP
junction plakoglobin
chr16_+_57662138 0.84 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr2_-_238499303 0.82 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr5_+_147582387 0.82 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr2_-_238499337 0.77 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr9_-_124991124 0.76 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr15_-_44486632 0.75 ENST00000484674.1
FRMD5
FERM domain containing 5
chr16_+_57662419 0.75 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr17_+_73717407 0.74 ENST00000579662.1
ITGB4
integrin, beta 4
chr2_-_238499131 0.72 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr11_+_128563652 0.71 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_73717551 0.69 ENST00000450894.3
ITGB4
integrin, beta 4
chr18_-_74207146 0.68 ENST00000443185.2
ZNF516
zinc finger protein 516
chr19_+_7953384 0.67 ENST00000306708.6
LRRC8E
leucine rich repeat containing 8 family, member E
chr11_+_128563948 0.63 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_22333943 0.61 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr5_-_78809950 0.61 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr11_+_59522837 0.58 ENST00000437946.2
STX3
syntaxin 3
chr1_-_153521597 0.58 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr19_-_35981358 0.57 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr1_-_6662919 0.55 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr1_-_153521714 0.54 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr11_-_75201791 0.54 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr17_+_7344057 0.53 ENST00000575398.1
ENST00000575082.1
FGF11
fibroblast growth factor 11
chrX_-_154563889 0.51 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr6_+_44194762 0.51 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_-_95009837 0.48 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr17_+_73717516 0.48 ENST00000200181.3
ENST00000339591.3
ITGB4
integrin, beta 4
chr8_-_125384927 0.47 ENST00000297632.6
TMEM65
transmembrane protein 65
chr6_+_47624172 0.46 ENST00000507065.1
ENST00000296862.1
GPR111
G protein-coupled receptor 111
chr6_+_151042224 0.46 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_-_35888905 0.44 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr17_-_27503770 0.44 ENST00000533112.1
MYO18A
myosin XVIIIA
chr5_+_135394840 0.44 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr6_+_47666275 0.41 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr6_+_32121218 0.40 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr6_-_35888824 0.40 ENST00000361690.3
ENST00000512445.1
SRPK1
SRSF protein kinase 1
chr15_+_77287426 0.40 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr17_+_21191341 0.38 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr17_+_72426891 0.38 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_-_98241760 0.38 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr7_-_142120321 0.37 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr1_+_247579451 0.35 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr4_+_76481258 0.35 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr11_-_123756334 0.35 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr3_-_98241358 0.34 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr2_+_103035102 0.32 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr12_-_53625958 0.32 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr19_-_55881741 0.32 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr2_+_16080659 0.31 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr17_+_74381343 0.31 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr6_+_33043703 0.31 ENST00000418931.2
ENST00000535465.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr7_+_55177416 0.30 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr4_+_166128735 0.30 ENST00000226725.6
KLHL2
kelch-like family member 2
chr1_+_165796753 0.30 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr18_+_9885961 0.28 ENST00000306084.6
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr1_+_27189631 0.28 ENST00000339276.4
SFN
stratifin
chr17_+_35851570 0.28 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr22_-_32860427 0.27 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr6_+_159290917 0.27 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr18_+_9885760 0.26 ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr11_-_47207390 0.24 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr9_+_137218362 0.24 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr7_+_73624327 0.24 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
LAT2
linker for activation of T cells family, member 2
chr1_+_27668505 0.24 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr14_+_97925151 0.24 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr11_-_2924720 0.24 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr5_-_175843524 0.23 ENST00000502877.1
CLTB
clathrin, light chain B
chr19_-_36019123 0.23 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr13_-_36429763 0.23 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr11_-_2924970 0.23 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr16_-_72206034 0.23 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr11_-_65667997 0.22 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr12_-_51402984 0.22 ENST00000545993.2
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr11_-_5462744 0.22 ENST00000380211.1
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr4_-_80329356 0.21 ENST00000358842.3
GK2
glycerol kinase 2
chr1_-_24126023 0.21 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chrX_+_65382433 0.21 ENST00000374727.3
HEPH
hephaestin
chr3_-_52869205 0.21 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr1_-_95007193 0.20 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr16_+_71560154 0.20 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chrX_-_153285251 0.20 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr17_-_48785216 0.20 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr2_+_27237615 0.20 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr16_+_71560023 0.20 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr1_-_24126051 0.19 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr4_+_108745711 0.19 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr12_-_118628350 0.19 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr6_+_159291090 0.19 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr5_-_158636512 0.19 ENST00000424310.2
RNF145
ring finger protein 145
chr8_-_68658578 0.19 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6
carboxypeptidase A6
chr6_-_127837739 0.19 ENST00000368268.2
SOGA3
SOGA family member 3
chr3_-_141747950 0.19 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_89459813 0.18 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr2_-_89521942 0.18 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr3_-_52868931 0.18 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr8_+_26150628 0.18 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_44584522 0.18 ENST00000372299.3
KLF17
Kruppel-like factor 17
chr11_-_65667884 0.18 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr17_+_79650962 0.18 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr10_-_86001210 0.17 ENST00000372105.3
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr22_+_39916558 0.17 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr5_-_137071756 0.17 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr3_-_113465065 0.17 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_-_30125177 0.17 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr17_+_25799008 0.17 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr20_-_634000 0.16 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr12_-_15114658 0.16 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_15114492 0.15 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_15114603 0.15 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr16_-_4665023 0.15 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr15_-_76304731 0.15 ENST00000394907.3
NRG4
neuregulin 4
chr17_-_39296739 0.15 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr1_-_207224307 0.14 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr17_-_27405875 0.14 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr7_+_39663061 0.14 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr9_+_140135665 0.13 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr7_-_135412925 0.13 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr2_+_69201705 0.13 ENST00000377938.2
GKN1
gastrokine 1
chr4_-_146019693 0.13 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr17_-_18161870 0.13 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
FLII
flightless I homolog (Drosophila)
chr16_-_4664860 0.13 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr4_-_100356844 0.13 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_-_29641104 0.12 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr12_-_15114191 0.12 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr3_-_141747439 0.12 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_-_94965667 0.12 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr9_+_125376948 0.12 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr2_-_97509749 0.11 ENST00000331001.2
ENST00000318357.4
ANKRD23
ankyrin repeat domain 23
chr4_-_100356551 0.11 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_+_123094369 0.10 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr22_+_23487513 0.10 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr17_-_39334460 0.09 ENST00000377726.2
KRTAP4-2
keratin associated protein 4-2
chr2_+_89999259 0.09 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr17_-_38956205 0.09 ENST00000306658.7
KRT28
keratin 28
chr20_-_17539456 0.09 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr8_+_99076750 0.09 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr3_-_196065248 0.09 ENST00000446879.1
ENST00000273695.3
TM4SF19
transmembrane 4 L six family member 19
chr7_+_112063192 0.09 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr18_+_21693306 0.08 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr10_+_121410882 0.08 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr22_-_39151947 0.08 ENST00000216064.4
SUN2
Sad1 and UNC84 domain containing 2
chr18_+_9885934 0.08 ENST00000357775.5
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr6_+_106959718 0.08 ENST00000369066.3
AIM1
absent in melanoma 1
chr11_+_68671310 0.08 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr11_-_47198380 0.08 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr5_+_14664762 0.07 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr13_-_52027134 0.07 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr11_-_64013288 0.07 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr12_-_49351303 0.07 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr17_-_73401567 0.07 ENST00000392562.1
GRB2
growth factor receptor-bound protein 2
chr14_+_73525144 0.06 ENST00000261973.7
ENST00000540173.1
RBM25
RNA binding motif protein 25
chr2_+_216974020 0.06 ENST00000392132.2
ENST00000417391.1
XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr9_-_139948468 0.06 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr17_-_28257080 0.06 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr6_-_31745085 0.06 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr2_-_169887827 0.06 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr3_-_32022733 0.05 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr7_-_141673573 0.05 ENST00000547270.1
TAS2R38
taste receptor, type 2, member 38
chr15_+_59903975 0.05 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr6_-_31745037 0.05 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr11_-_2193025 0.05 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH
tyrosine hydroxylase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.6 16.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 2.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.5 2.3 GO:0002159 desmosome assembly(GO:0002159)
0.5 2.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 1.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 1.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 1.5 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3 0.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.2 1.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 1.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 1.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 1.7 GO:0051546 keratinocyte migration(GO:0051546)
0.1 2.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.3 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.9 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.1 0.8 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 1.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 1.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 2.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.2 GO:0006953 acute-phase response(GO:0006953)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0042214 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.0 0.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:1904430 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 5.6 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.4 GO:0005610 laminin-5 complex(GO:0005610)
0.2 2.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 2.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 1.6 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.3 1.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 2.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 3.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 2.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 16.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 17.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants