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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOSL2_SMARCC1

Z-value: 0.86

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
FOSL2
ENSG00000075426.7 FOSL2
SMARCC1
ENSG00000173473.6 SMARCC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL2hg19_v2_chr2_+_28618532_28618610-0.157.2e-01Click!
SMARCC1hg19_v2_chr3_-_47823298_47823423-0.029.7e-01Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_21452964 7.45 ENST00000587184.1
 LAMA3
 laminin, alpha 3
chr18_+_21452804 7.35 ENST00000269217.6
 LAMA3
 laminin, alpha 3
chr19_-_36004543 2.62 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
 DMKN
 dermokine
chr17_-_39769005 2.61 ENST00000301653.4
ENST00000593067.1
 KRT16
 keratin 16
chr19_-_35992780 2.53 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
 DMKN
 dermokine
chr15_+_41136586 2.14 ENST00000431806.1
 SPINT1
 serine peptidase inhibitor, Kunitz type 1
chr20_+_44637526 2.13 ENST00000372330.3
 MMP9
 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr18_+_61442629 1.85 ENST00000398019.2
ENST00000540675.1
 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_102668879 1.76 ENST00000315274.6
 MMP1
 matrix metallopeptidase 1 (interstitial collagenase)
chr2_+_102618428 1.73 ENST00000457817.1
 IL1R2
 interleukin 1 receptor, type II
chr19_-_51523412 1.71 ENST00000391805.1
ENST00000599077.1
 KLK10
 kallikrein-related peptidase 10
chr15_+_40532058 1.70 ENST00000260404.4
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr3_-_151034734 1.69 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr19_-_51523275 1.59 ENST00000309958.3
 KLK10
 kallikrein-related peptidase 10
chr7_+_73245193 1.53 ENST00000340958.2
 CLDN4
 claudin 4
chr11_+_394196 1.53 ENST00000331563.2
ENST00000531857.1
 PKP3
 plakophilin 3
chr16_+_57662138 1.44 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
 GPR56
 G protein-coupled receptor 56
chr1_-_21059029 1.36 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
 SH2D5
 SH2 domain containing 5
chr11_+_12308447 1.35 ENST00000256186.2
 MICALCL
 MICAL C-terminal like
chr16_+_57662419 1.29 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
 GPR56
 G protein-coupled receptor 56
chr18_+_34124507 1.25 ENST00000591635.1
 FHOD3
 formin homology 2 domain containing 3
chr15_+_41136216 1.22 ENST00000562057.1
ENST00000344051.4
 SPINT1
 serine peptidase inhibitor, Kunitz type 1
chr1_+_183155373 1.19 ENST00000493293.1
ENST00000264144.4
 LAMC2
 laminin, gamma 2
chr1_+_35220613 1.16 ENST00000338513.1
 GJB5
 gap junction protein, beta 5, 31.1kDa
chr12_-_53343602 1.12 ENST00000546897.1
ENST00000552551.1
 KRT8
 keratin 8
chr11_+_10476851 1.09 ENST00000396553.2
 AMPD3
 adenosine monophosphate deaminase 3
chr12_-_52845910 1.07 ENST00000252252.3
 KRT6B
 keratin 6B
chr11_-_108408895 0.98 ENST00000443411.1
ENST00000533052.1
 EXPH5
 exophilin 5
chr19_+_39279838 0.96 ENST00000314980.4
 LGALS7B
 lectin, galactoside-binding, soluble, 7B
chr2_+_113875466 0.92 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
 IL1RN
 interleukin 1 receptor antagonist
chr15_+_40531243 0.92 ENST00000558055.1
ENST00000455577.2
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr11_-_118134997 0.92 ENST00000278937.2
 MPZL2
 myelin protein zero-like 2
chr19_-_51504411 0.91 ENST00000593490.1
 KLK8
 kallikrein-related peptidase 8
chr2_-_113542063 0.91 ENST00000263339.3
 IL1A
 interleukin 1, alpha
chr15_+_40531621 0.88 ENST00000560346.1
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr10_+_24755416 0.87 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
 KIAA1217
 KIAA1217
chr19_-_44174330 0.85 ENST00000340093.3
 PLAUR
 plasminogen activator, urokinase receptor
chr17_+_55162453 0.82 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
 AKAP1
 A kinase (PRKA) anchor protein 1
chr18_+_61445007 0.82 ENST00000447428.1
ENST00000546027.1
 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_98241358 0.81 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
 CLDND1
 claudin domain containing 1
chr1_+_15256230 0.79 ENST00000376028.4
ENST00000400798.2
 KAZN
 kazrin, periplakin interacting protein
chr12_-_95009837 0.78 ENST00000551457.1
 TMCC3
 transmembrane and coiled-coil domain family 3
chr19_-_44174305 0.77 ENST00000601723.1
ENST00000339082.3
 PLAUR
 plasminogen activator, urokinase receptor
chr8_+_120220561 0.77 ENST00000276681.6
 MAL2
 mal, T-cell differentiation protein 2 (gene/pseudogene)
chr6_+_47666275 0.75 ENST00000327753.3
ENST00000283303.2
 GPR115
 G protein-coupled receptor 115
chr11_-_118135160 0.74 ENST00000438295.2
 MPZL2
 myelin protein zero-like 2
chr12_-_95510743 0.73 ENST00000551521.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr1_-_153521714 0.73 ENST00000368713.3
 S100A3
 S100 calcium binding protein A3
chr1_-_153521597 0.73 ENST00000368712.1
 S100A3
 S100 calcium binding protein A3
chr7_+_26331541 0.71 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
 SNX10
 sorting nexin 10
chr6_+_41604747 0.71 ENST00000419164.1
ENST00000373051.2
 MDFI
 MyoD family inhibitor
chr4_-_36246060 0.70 ENST00000303965.4
 ARAP2
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_82644669 0.70 ENST00000297265.4
 CHMP4C
 charged multivesicular body protein 4C
chr3_-_12800751 0.69 ENST00000435218.2
ENST00000435575.1
 TMEM40
 transmembrane protein 40
chr17_-_7493390 0.68 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
 SOX15
 SRY (sex determining region Y)-box 15
chr18_-_74207146 0.68 ENST00000443185.2
 ZNF516
 zinc finger protein 516
chr6_+_47624172 0.66 ENST00000507065.1
ENST00000296862.1
 GPR111
 G protein-coupled receptor 111
chr1_+_2004901 0.64 ENST00000400921.2
 PRKCZ
 protein kinase C, zeta
chr19_-_39264072 0.63 ENST00000599035.1
ENST00000378626.4
 LGALS7
 lectin, galactoside-binding, soluble, 7
chr17_-_27503770 0.63 ENST00000533112.1
 MYO18A
 myosin XVIIIA
chr1_-_156675368 0.63 ENST00000368222.3
 CRABP2
 cellular retinoic acid binding protein 2
chr2_+_220492373 0.61 ENST00000317151.3
 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
chr1_+_2005425 0.61 ENST00000461106.2
 PRKCZ
 protein kinase C, zeta
chr1_-_28520447 0.61 ENST00000539896.1
 PTAFR
 platelet-activating factor receptor
chr3_+_124223586 0.60 ENST00000393496.1
 KALRN
 kalirin, RhoGEF kinase
chr17_+_48610074 0.60 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
 EPN3
 epsin 3
chr10_-_6019984 0.59 ENST00000525219.2
 IL15RA
 interleukin 15 receptor, alpha
chr14_+_96722539 0.58 ENST00000553356.1
 BDKRB1
 bradykinin receptor B1
chr12_+_56473628 0.57 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
 ERBB3
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_+_62649158 0.56 ENST00000539891.1
ENST00000536981.1
 SLC3A2
 solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_6662919 0.56 ENST00000377658.4
ENST00000377663.3
 KLHL21
 kelch-like family member 21
chr2_-_113594279 0.56 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B
 interleukin 1, beta
chr9_+_35673853 0.55 ENST00000378357.4
 CA9
 carbonic anhydrase IX
chr16_+_30751953 0.55 ENST00000483578.1
 RP11-2C24.4
 RP11-2C24.4
chr17_+_30771279 0.55 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
 PSMD11
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr10_-_6019552 0.55 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
 IL15RA
 interleukin 15 receptor, alpha
chr1_-_209824643 0.55 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr1_-_28520384 0.54 ENST00000305392.3
 PTAFR
 platelet-activating factor receptor
chr13_-_86373536 0.54 ENST00000400286.2
 SLITRK6
 SLIT and NTRK-like family, member 6
chr1_-_153029980 0.54 ENST00000392653.2
 SPRR2A
 small proline-rich protein 2A
chr19_-_36019123 0.48 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
 SBSN
 suprabasin
chr18_+_61254570 0.47 ENST00000344731.5
 SERPINB13
 serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr2_-_238499303 0.47 ENST00000409576.1
 RAB17
 RAB17, member RAS oncogene family
chr4_+_76481258 0.46 ENST00000311623.4
ENST00000435974.2
 C4orf26
 chromosome 4 open reading frame 26
chr6_+_30852130 0.46 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr22_+_45072925 0.46 ENST00000006251.7
 PRR5
 proline rich 5 (renal)
chr22_+_45072958 0.46 ENST00000403581.1
 PRR5
 proline rich 5 (renal)
chr14_+_96722152 0.44 ENST00000216629.6
 BDKRB1
 bradykinin receptor B1
chr6_+_106546808 0.44 ENST00000369089.3
 PRDM1
 PR domain containing 1, with ZNF domain
chr15_+_89182178 0.44 ENST00000559876.1
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr11_-_75201791 0.43 ENST00000529721.1
 GDPD5
 glycerophosphodiester phosphodiesterase domain containing 5
chr15_+_89181974 0.43 ENST00000306072.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr6_+_44194762 0.41 ENST00000371708.1
 SLC29A1
 solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_-_20256965 0.41 ENST00000400331.5
ENST00000332878.4
 MACC1
 metastasis associated in colon cancer 1
chrX_-_33229636 0.41 ENST00000357033.4
 DMD
 dystrophin
chr13_+_78109804 0.41 ENST00000535157.1
 SCEL
 sciellin
chr13_+_78109884 0.40 ENST00000377246.3
ENST00000349847.3
 SCEL
 sciellin
chr1_-_43751230 0.40 ENST00000523677.1
 C1orf210
 chromosome 1 open reading frame 210
chr19_-_35981358 0.40 ENST00000484218.2
ENST00000338897.3
 KRTDAP
 keratinocyte differentiation-associated protein
chr14_+_21510385 0.40 ENST00000298690.4
 RNASE7
 ribonuclease, RNase A family, 7
chr10_+_75670862 0.39 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
 PLAU
 plasminogen activator, urokinase
chr8_+_124780672 0.39 ENST00000521166.1
ENST00000334705.7
 FAM91A1
 family with sequence similarity 91, member A1
chr16_+_22308717 0.39 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
 POLR3E
 polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr20_+_48909240 0.39 ENST00000371639.3
 RP11-290F20.1
 RP11-290F20.1
chr9_-_23826298 0.39 ENST00000380117.1
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr9_-_124991124 0.39 ENST00000394319.4
ENST00000340587.3
 LHX6
 LIM homeobox 6
chr19_+_7953384 0.38 ENST00000306708.6
 LRRC8E
 leucine rich repeat containing 8 family, member E
chr17_-_39942940 0.38 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
 JUP
 junction plakoglobin
chr17_-_8021710 0.38 ENST00000380149.1
ENST00000448843.2
 ALOXE3
 arachidonate lipoxygenase 3
chr6_-_138428613 0.38 ENST00000421351.3
 PERP
 PERP, TP53 apoptosis effector
chr2_+_86668464 0.38 ENST00000409064.1
 KDM3A
 lysine (K)-specific demethylase 3A
chr2_-_238499131 0.38 ENST00000538644.1
 RAB17
 RAB17, member RAS oncogene family
chr15_+_89182156 0.38 ENST00000379224.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr2_-_238499337 0.37 ENST00000411462.1
ENST00000409822.1
 RAB17
 RAB17, member RAS oncogene family
chr11_+_1856034 0.36 ENST00000341958.3
 SYT8
 synaptotagmin VIII
chr17_+_73717407 0.35 ENST00000579662.1
 ITGB4
 integrin, beta 4
chr3_-_122512619 0.35 ENST00000383659.1
ENST00000306103.2
 HSPBAP1
 HSPB (heat shock 27kDa) associated protein 1
chrX_-_15683147 0.34 ENST00000380342.3
 TMEM27
 transmembrane protein 27
chr17_+_73717551 0.34 ENST00000450894.3
 ITGB4
 integrin, beta 4
chr5_+_145316120 0.34 ENST00000359120.4
 SH3RF2
 SH3 domain containing ring finger 2
chr5_+_150020214 0.34 ENST00000307662.4
 SYNPO
 synaptopodin
chr11_+_1855645 0.34 ENST00000381968.3
ENST00000381978.3
 SYT8
 synaptotagmin VIII
chr10_+_104155450 0.33 ENST00000471698.1
ENST00000189444.6
 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_+_84457250 0.33 ENST00000395226.2
 AGPAT9
 1-acylglycerol-3-phosphate O-acyltransferase 9
chr1_-_153113927 0.33 ENST00000368752.4
 SPRR2B
 small proline-rich protein 2B
chrX_-_24665208 0.33 ENST00000356768.4
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chrX_-_154563889 0.32 ENST00000369449.2
ENST00000321926.4
 CLIC2
 chloride intracellular channel 2
chr17_+_21191341 0.32 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
 MAP2K3
 mitogen-activated protein kinase kinase 3
chr11_+_128563652 0.32 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr6_-_30712313 0.32 ENST00000376377.2
ENST00000259874.5
 IER3
 immediate early response 3
chr3_+_36421826 0.32 ENST00000273183.3
 STAC
 SH3 and cysteine rich domain
chr19_-_51472823 0.32 ENST00000310157.2
 KLK6
 kallikrein-related peptidase 6
chr4_+_84457529 0.32 ENST00000264409.4
 AGPAT9
 1-acylglycerol-3-phosphate O-acyltransferase 9
chr15_-_44486632 0.32 ENST00000484674.1
 FRMD5
 FERM domain containing 5
chr19_+_15052301 0.31 ENST00000248072.3
 OR7C2
 olfactory receptor, family 7, subfamily C, member 2
chr1_+_36621697 0.31 ENST00000373150.4
ENST00000373151.2
 MAP7D1
 MAP7 domain containing 1
chr2_-_64371546 0.30 ENST00000358912.4
 PELI1
 pellino E3 ubiquitin protein ligase 1
chr17_-_39743139 0.30 ENST00000167586.6
 KRT14
 keratin 14
chr16_-_30125177 0.30 ENST00000406256.3
 GDPD3
 glycerophosphodiester phosphodiesterase domain containing 3
chr5_+_35856951 0.30 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
 IL7R
 interleukin 7 receptor
chr6_+_32121218 0.29 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
 PPT2
 palmitoyl-protein thioesterase 2
chr6_+_151042224 0.29 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr5_-_78809950 0.28 ENST00000334082.6
 HOMER1
 homer homolog 1 (Drosophila)
chr4_+_108745711 0.28 ENST00000394684.4
 SGMS2
 sphingomyelin synthase 2
chr10_-_6019455 0.27 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
 IL15RA
 interleukin 15 receptor, alpha
chr1_-_9970227 0.27 ENST00000377263.1
 CTNNBIP1
 catenin, beta interacting protein 1
chr12_+_56732658 0.26 ENST00000228534.4
 IL23A
 interleukin 23, alpha subunit p19
chr18_-_35065710 0.26 ENST00000589229.1
ENST00000587819.1
 CELF4
 CUGBP, Elav-like family member 4
chr8_-_141774467 0.26 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
 PTK2
 protein tyrosine kinase 2
chr22_-_37584321 0.26 ENST00000397110.2
ENST00000337843.2
 C1QTNF6
 C1q and tumor necrosis factor related protein 6
chr11_+_66742742 0.26 ENST00000308963.4
 C11orf86
 chromosome 11 open reading frame 86
chr19_+_36203830 0.26 ENST00000262630.3
 ZBTB32
 zinc finger and BTB domain containing 32
chr6_+_31082603 0.25 ENST00000259881.9
 PSORS1C1
 psoriasis susceptibility 1 candidate 1
chrX_-_24665353 0.25 ENST00000379144.2
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr6_+_138188551 0.25 ENST00000237289.4
ENST00000433680.1
 TNFAIP3
 tumor necrosis factor, alpha-induced protein 3
chr20_-_1309809 0.25 ENST00000360779.3
 SDCBP2
 syndecan binding protein (syntenin) 2
chr17_+_35851570 0.25 ENST00000394386.1
 DUSP14
 dual specificity phosphatase 14
chr5_+_135394840 0.24 ENST00000503087.1
 TGFBI
 transforming growth factor, beta-induced, 68kDa
chr7_+_48128194 0.24 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
 UPP1
 uridine phosphorylase 1
chr7_+_48128316 0.24 ENST00000341253.4
 UPP1
 uridine phosphorylase 1
chr11_+_128563948 0.24 ENST00000534087.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr5_-_134914673 0.24 ENST00000512158.1
 CXCL14
 chemokine (C-X-C motif) ligand 14
chr12_-_95044309 0.24 ENST00000261226.4
 TMCC3
 transmembrane and coiled-coil domain family 3
chr17_+_73717516 0.24 ENST00000200181.3
ENST00000339591.3
 ITGB4
 integrin, beta 4
chr12_+_9144626 0.24 ENST00000543895.1
 KLRG1
 killer cell lectin-like receptor subfamily G, member 1
chr10_-_129691195 0.24 ENST00000368671.3
 CLRN3
 clarin 3
chr1_+_161692449 0.23 ENST00000367946.3
ENST00000367945.1
ENST00000336830.5
ENST00000367944.3
ENST00000392158.1
 FCRLB
 Fc receptor-like B
chr11_+_59522837 0.22 ENST00000437946.2
 STX3
 syntaxin 3
chr17_-_41623075 0.22 ENST00000545089.1
 ETV4
 ets variant 4
chr1_+_27189631 0.22 ENST00000339276.4
 SFN
 stratifin
chr13_-_36429763 0.21 ENST00000379893.1
 DCLK1
 doublecortin-like kinase 1
chr11_-_47207390 0.21 ENST00000539589.1
ENST00000528462.1
 PACSIN3
 protein kinase C and casein kinase substrate in neurons 3
chr17_+_78075361 0.21 ENST00000577106.1
ENST00000390015.3
 GAA
 glucosidase, alpha; acid
chr18_-_53253323 0.21 ENST00000540999.1
ENST00000563888.2
 TCF4
 transcription factor 4
chr2_+_220306745 0.21 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
 SPEG
 SPEG complex locus
chr2_+_89998789 0.20 ENST00000453166.2
 IGKV2D-28
 immunoglobulin kappa variable 2D-28
chr5_+_141016969 0.20 ENST00000518856.1
 RELL2
 RELT-like 2
chr4_-_170947485 0.20 ENST00000504999.1
 MFAP3L
 microfibrillar-associated protein 3-like
chr19_+_17865011 0.20 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
 FCHO1
 FCH domain only 1
chr6_-_29324054 0.20 ENST00000543825.1
 OR5V1
 olfactory receptor, family 5, subfamily V, member 1
chr3_+_160394940 0.20 ENST00000320767.2
 ARL14
 ADP-ribosylation factor-like 14
chr22_+_21987005 0.20 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
 CCDC116
 coiled-coil domain containing 116
chr6_-_35888905 0.19 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
 SRPK1
 SRSF protein kinase 1
chr13_+_80055581 0.19 ENST00000487865.1
 NDFIP2
 Nedd4 family interacting protein 2
chr6_-_35888824 0.19 ENST00000361690.3
ENST00000512445.1
 SRPK1
 SRSF protein kinase 1
chr2_-_89521942 0.19 ENST00000482769.1
 IGKV2-28
 immunoglobulin kappa variable 2-28
chr17_-_41623259 0.19 ENST00000538265.1
ENST00000591713.1
 ETV4
 ets variant 4
chr18_-_53253112 0.19 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
 TCF4
 transcription factor 4
chr17_+_78075498 0.19 ENST00000302262.3
 GAA
 glucosidase, alpha; acid
chr8_-_143851203 0.19 ENST00000521396.1
ENST00000317543.7
 LYNX1
 Ly6/neurotoxin 1
chr16_+_28996364 0.19 ENST00000564277.1
 LAT
 linker for activation of T cells
chr3_+_184037466 0.18 ENST00000441154.1
 EIF4G1
 eukaryotic translation initiation factor 4 gamma, 1
chr2_+_89923550 0.18 ENST00000509129.1
 IGKV1D-37
 immunoglobulin kappa variable 1D-37 (non-functional)
chr4_-_76944621 0.18 ENST00000306602.1
 CXCL10
 chemokine (C-X-C motif) ligand 10
chr1_+_36621529 0.18 ENST00000316156.4
 MAP7D1
 MAP7 domain containing 1
chr6_-_44233361 0.18 ENST00000275015.5
 NFKBIE
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr6_+_33043703 0.18 ENST00000418931.2
ENST00000535465.1
 HLA-DPB1
 major histocompatibility complex, class II, DP beta 1
chr22_+_22781853 0.18 ENST00000390300.2
 IGLV5-37
 immunoglobulin lambda variable 5-37
chr2_-_166651191 0.18 ENST00000392701.3
 GALNT3
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr16_-_2908155 0.18 ENST00000571228.1
ENST00000161006.3
 PRSS22
 protease, serine, 22

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.7 2.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.6 17.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.7 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.4 3.8 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.4 1.2 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.4 1.9 GO:0002159 desmosome assembly(GO:0002159)
0.3 1.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.7 GO:0048627 myoblast development(GO:0048627)
0.2 0.6 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.4 GO:0051302 regulation of cell division(GO:0051302)
0.2 0.6 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 1.1 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 3.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 0.8 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 4.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.7 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.9 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.9 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.6 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 1.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.3 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.3 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.5 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.8 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.3 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.9 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0006778 porphyrin-containing compound metabolic process(GO:0006778)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0014806 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.1 GO:0021700 developmental maturation(GO:0021700)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.9 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 1.3 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0003231 cardiac ventricle development(GO:0003231)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.9 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.0 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.0 GO:0072017 distal tubule development(GO:0072017)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 15.3 GO:0005610 laminin-5 complex(GO:0005610)
0.4 1.2 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.3 GO:0045179 apical cortex(GO:0045179)
0.1 0.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 3.2 GO:0030057 desmosome(GO:0030057)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 1.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 1.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 1.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 1.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.3 1.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.3 0.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.4 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.3 GO:0070026 nitric oxide binding(GO:0070026)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 3.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 15.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 4.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 2.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 18.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis