Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
FOXA2 Links Ensembl NCBI GeneCards UniProt	ENSG00000125798.10	FOXA2
FOXJ3 Links Ensembl NCBI GeneCards UniProt	ENSG00000198815.4	FOXJ3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXA2	hg19_v2_chr20_-_22566089_22566097, hg19_v2_chr20_-_22565101_22565223	-0.87	4.5e-03	Click!
FOXJ3	hg19_v2_chr1_-_42800614_42800649, hg19_v2_chr1_-_42801540_42801562, hg19_v2_chr1_-_42800860_42800912	-0.82	1.2e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr12_-_91574142	2.81	ENST00000547937.1	DCN	decorin
chr12_-_15038779	2.10	ENST00000228938.5 ENST00000539261.1	MGP	matrix Gla protein
chr3_+_69928256	1.14	ENST00000394355.2	MITF	microphthalmia-associated transcription factor
chr12_-_92539614	1.07	ENST00000256015.3	BTG1	B-cell translocation gene 1, anti-proliferative
chr10_+_70847852	1.05	ENST00000242465.3	SRGN	serglycin
chr2_+_233527443	0.95	ENST00000410095.1	EFHD1	EF-hand domain family, member D1
chr4_-_138453606	0.92	ENST00000412923.2 ENST00000344876.4 ENST00000507846.1 ENST00000510305.1	PCDH18	protocadherin 18
chr20_+_45338126	0.89	ENST00000359271.2	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10
chr1_+_163039143	0.85	ENST00000531057.1 ENST00000527809.1 ENST00000367908.4	RGS4	regulator of G-protein signaling 4
chr1_+_221054584	0.75	ENST00000549319.1	HLX	H2.0-like homeobox
chr3_+_148447887	0.73	ENST00000475347.1 ENST00000474935.1 ENST00000461609.1	AGTR1	angiotensin II receptor, type 1
chrX_+_9431324	0.71	ENST00000407597.2 ENST00000424279.1 ENST00000536365.1 ENST00000441088.1 ENST00000380961.1 ENST00000415293.1	TBL1X	transducin (beta)-like 1X-linked
chr5_+_140529630	0.63	ENST00000543635.1	PCDHB6	protocadherin beta 6
chr1_-_24194771	0.61	ENST00000374479.3	FUCA1	fucosidase, alpha-L- 1, tissue
chr12_+_59989918	0.60	ENST00000547379.1 ENST00000549465.1	SLC16A7	solute carrier family 16 (monocarboxylate transporter), member 7
chr17_-_66951474	0.60	ENST00000269080.2	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr2_-_202563414	0.58	ENST00000409474.3 ENST00000315506.7 ENST00000359962.5	MPP4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr5_-_19988339	0.57	ENST00000382275.1	CDH18	cadherin 18, type 2
chr6_-_117747015	0.57	ENST00000368508.3 ENST00000368507.3	ROS1	c-ros oncogene 1 , receptor tyrosine kinase
chr2_+_88047606	0.56	ENST00000359481.4	PLGLB2	plasminogen-like B2
chr12_-_15374343	0.56	ENST00000256953.2 ENST00000546331.1	RERG	RAS-like, estrogen-regulated, growth inhibitor
chr6_+_122793058	0.54	ENST00000392491.2	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr2_+_109223595	0.53	ENST00000410093.1	LIMS1	LIM and senescent cell antigen-like domains 1
chr14_-_74551096	0.51	ENST00000350259.4	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chrX_+_85969626	0.51	ENST00000484479.1	DACH2	dachshund homolog 2 (Drosophila)
chr9_+_120466610	0.50	ENST00000394487.4	TLR4	toll-like receptor 4
chr1_-_92371839	0.50	ENST00000370399.2	TGFBR3	transforming growth factor, beta receptor III
chr2_+_201450591	0.49	ENST00000374700.2	AOX1	aldehyde oxidase 1
chr2_+_120770581	0.49	ENST00000263713.5	EPB41L5	erythrocyte membrane protein band 4.1 like 5
chr4_-_138453559	0.47	ENST00000511115.1	PCDH18	protocadherin 18
chr9_+_120466650	0.47	ENST00000355622.6	TLR4	toll-like receptor 4
chr3_-_187455680	0.47	ENST00000438077.1	BCL6	B-cell CLL/lymphoma 6
chr6_+_101846664	0.45	ENST00000421544.1 ENST00000413795.1 ENST00000369138.1 ENST00000358361.3	GRIK2	glutamate receptor, ionotropic, kainate 2
chr2_+_175260514	0.45	ENST00000424069.1 ENST00000427038.1	SCRN3	secernin 3
chr9_-_21305312	0.44	ENST00000259555.4	IFNA5	interferon, alpha 5
chr14_+_88471468	0.41	ENST00000267549.3	GPR65	G protein-coupled receptor 65
chr18_-_25616519	0.41	ENST00000399380.3	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr1_+_150122034	0.40	ENST00000025469.6 ENST00000369124.4	PLEKHO1	pleckstrin homology domain containing, family O member 1
chr2_+_175260451	0.39	ENST00000458563.1 ENST00000409673.3 ENST00000272732.6 ENST00000435964.1	SCRN3	secernin 3
chr1_+_185703513	0.39	ENST00000271588.4 ENST00000367492.2	HMCN1	hemicentin 1
chr17_-_26662440	0.39	ENST00000578122.1	IFT20	intraflagellar transport 20 homolog (Chlamydomonas)
chr7_+_6617039	0.39	ENST00000405731.3 ENST00000396713.2 ENST00000396707.2 ENST00000335965.6 ENST00000396709.1 ENST00000483589.1 ENST00000396706.2	ZDHHC4	zinc finger, DHHC-type containing 4
chr17_-_26662464	0.38	ENST00000579419.1 ENST00000585313.1 ENST00000395418.3 ENST00000578985.1 ENST00000577498.1 ENST00000585089.1 ENST00000357896.3	IFT20	intraflagellar transport 20 homolog (Chlamydomonas)
chr14_-_74551172	0.38	ENST00000553458.1	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr21_-_31869451	0.38	ENST00000334058.2	KRTAP19-4	keratin associated protein 19-4
chr17_-_19290483	0.37	ENST00000395592.2 ENST00000299610.4	MFAP4	microfibrillar-associated protein 4
chr7_+_149570049	0.37	ENST00000421974.2 ENST00000456496.2	ATP6V0E2	ATPase, H+ transporting V0 subunit e2
chr5_-_159846399	0.37	ENST00000297151.4	SLU7	SLU7 splicing factor homolog (S. cerevisiae)
chr8_+_70404996	0.35	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr19_-_58662139	0.35	ENST00000598312.1	ZNF329	zinc finger protein 329
chr2_+_201170703	0.34	ENST00000358677.5	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr15_-_55657428	0.34	ENST00000568543.1	CCPG1	cell cycle progression 1
chr5_+_159436120	0.33	ENST00000522793.1 ENST00000231238.5	TTC1	tetratricopeptide repeat domain 1
chr7_+_151038850	0.32	ENST00000355851.4 ENST00000566856.1 ENST00000470229.1	NUB1	negative regulator of ubiquitin-like proteins 1
chr6_+_21666633	0.31	ENST00000606851.1	CASC15	cancer susceptibility candidate 15 (non-protein coding)
chr1_+_178310581	0.30	ENST00000462775.1	RASAL2	RAS protein activator like 2
chr2_+_65283506	0.30	ENST00000377990.2	CEP68	centrosomal protein 68kDa
chr10_-_25010795	0.30	ENST00000416305.1 ENST00000376410.2	ARHGAP21	Rho GTPase activating protein 21
chr12_+_79439405	0.30	ENST00000552744.1	SYT1	synaptotagmin I
chr13_-_39564993	0.29	ENST00000423210.1	STOML3	stomatin (EPB72)-like 3
chr6_+_108882069	0.29	ENST00000406360.1	FOXO3	forkhead box O3
chr17_-_30185946	0.29	ENST00000579741.1	COPRS	coordinator of PRMT5, differentiation stimulator
chr7_+_106809406	0.29	ENST00000468410.1 ENST00000478930.1 ENST00000464009.1 ENST00000222574.4	HBP1	HMG-box transcription factor 1
chr5_-_146833222	0.28	ENST00000534907.1	DPYSL3	dihydropyrimidinase-like 3
chr1_+_78470530	0.27	ENST00000370763.5	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_+_109204743	0.27	ENST00000332345.6	LIMS1	LIM and senescent cell antigen-like domains 1
chr5_-_131132614	0.27	ENST00000307968.7 ENST00000307954.8	FNIP1	folliculin interacting protein 1
chr6_+_12717892	0.27	ENST00000379350.1	PHACTR1	phosphatase and actin regulator 1
chr2_+_65283529	0.27	ENST00000546106.1 ENST00000537589.1 ENST00000260569.4	CEP68	centrosomal protein 68kDa
chr19_-_9546177	0.27	ENST00000592292.1 ENST00000588221.1	ZNF266	zinc finger protein 266
chrX_-_106959631	0.26	ENST00000486554.1 ENST00000372390.4	TSC22D3	TSC22 domain family, member 3
chrX_+_10124977	0.26	ENST00000380833.4	CLCN4	chloride channel, voltage-sensitive 4
chr13_-_49975632	0.26	ENST00000457041.1 ENST00000355854.4	CAB39L	calcium binding protein 39-like
chr17_-_30185971	0.25	ENST00000378634.2	COPRS	coordinator of PRMT5, differentiation stimulator
chr2_+_12857043	0.25	ENST00000381465.2	TRIB2	tribbles pseudokinase 2
chr2_+_109204909	0.25	ENST00000393310.1	LIMS1	LIM and senescent cell antigen-like domains 1
chr2_+_210517895	0.24	ENST00000447185.1	MAP2	microtubule-associated protein 2
chr2_-_87248975	0.23	ENST00000409310.2 ENST00000355705.3	PLGLB1	plasminogen-like B1
chr10_-_14050522	0.23	ENST00000342409.2	FRMD4A	FERM domain containing 4A
chr2_-_224702740	0.23	ENST00000444408.1	AP1S3	adaptor-related protein complex 1, sigma 3 subunit
chr13_-_61989655	0.23	ENST00000409204.4	PCDH20	protocadherin 20
chr19_+_18111927	0.22	ENST00000379656.3	ARRDC2	arrestin domain containing 2
chr5_+_135468516	0.22	ENST00000507118.1 ENST00000511116.1 ENST00000545279.1 ENST00000545620.1	SMAD5	SMAD family member 5
chr3_-_150920979	0.22	ENST00000309180.5 ENST00000480322.1	GPR171	G protein-coupled receptor 171
chr15_-_81616446	0.22	ENST00000302824.6	STARD5	StAR-related lipid transfer (START) domain containing 5
chr6_-_87804815	0.22	ENST00000369582.2	CGA	glycoprotein hormones, alpha polypeptide
chr11_-_26593677	0.22	ENST00000527569.1	MUC15	mucin 15, cell surface associated
chr3_+_159570722	0.22	ENST00000482804.1	SCHIP1	schwannomin interacting protein 1
chrX_+_120181457	0.22	ENST00000328078.1	GLUD2	glutamate dehydrogenase 2
chr5_-_88119580	0.22	ENST00000539796.1	MEF2C	myocyte enhancer factor 2C
chr10_-_4285923	0.21	ENST00000418372.1 ENST00000608792.1	LINC00702	long intergenic non-protein coding RNA 702
chrX_+_54947229	0.21	ENST00000442098.1 ENST00000430420.1 ENST00000453081.1 ENST00000173898.7 ENST00000319167.8 ENST00000375022.4 ENST00000399736.1 ENST00000440072.1 ENST00000420798.2 ENST00000431115.1 ENST00000440759.1 ENST00000375041.2	TRO	trophinin
chr12_-_92536433	0.21	ENST00000551563.2 ENST00000546975.1 ENST00000549802.1	C12orf79	chromosome 12 open reading frame 79
chr2_+_120770645	0.20	ENST00000443902.2	EPB41L5	erythrocyte membrane protein band 4.1 like 5
chr12_+_21679220	0.20	ENST00000256969.2	C12orf39	chromosome 12 open reading frame 39
chr11_+_20044096	0.20	ENST00000533917.1	NAV2	neuron navigator 2
chr1_+_74701062	0.20	ENST00000326637.3	TNNI3K	TNNI3 interacting kinase
chr4_+_74347400	0.20	ENST00000226355.3	AFM	afamin
chr11_-_26593779	0.20	ENST00000529533.1	MUC15	mucin 15, cell surface associated
chr16_+_66442411	0.19	ENST00000499966.1	LINC00920	long intergenic non-protein coding RNA 920
chr1_-_57431679	0.19	ENST00000371237.4 ENST00000535057.1 ENST00000543257.1	C8B	complement component 8, beta polypeptide
chr5_+_140625147	0.19	ENST00000231173.3	PCDHB15	protocadherin beta 15
chr1_-_20126365	0.19	ENST00000294543.6 ENST00000375122.2	TMCO4	transmembrane and coiled-coil domains 4
chr2_-_175260368	0.18	ENST00000342016.3 ENST00000362053.5	CIR1	corepressor interacting with RBPJ, 1
chr10_+_90672113	0.18	ENST00000371922.1	STAMBPL1	STAM binding protein-like 1
chr5_+_140729649	0.18	ENST00000523390.1	PCDHGB1	protocadherin gamma subfamily B, 1
chr16_-_80926457	0.18	ENST00000563626.1 ENST00000562231.1	RP11-314O13.1	RP11-314O13.1
chr6_-_122792919	0.18	ENST00000339697.4	SERINC1	serine incorporator 1
chr1_+_203765437	0.18	ENST00000550078.1	ZBED6	zinc finger, BED-type containing 6
chr2_-_65593784	0.17	ENST00000443619.2	SPRED2	sprouty-related, EVH1 domain containing 2
chr4_-_21950356	0.17	ENST00000447367.2 ENST00000382152.2	KCNIP4	Kv channel interacting protein 4
chr5_+_141346385	0.17	ENST00000513019.1 ENST00000356143.1	RNF14	ring finger protein 14
chr9_+_70856397	0.17	ENST00000360171.6	CBWD3	COBW domain containing 3
chr2_+_166095898	0.17	ENST00000424833.1 ENST00000375437.2 ENST00000357398.3	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr4_+_88754113	0.17	ENST00000560249.1 ENST00000540395.1 ENST00000511670.1 ENST00000361056.3	MEPE	matrix extracellular phosphoglycoprotein
chr12_-_7596735	0.17	ENST00000416109.2 ENST00000396630.1 ENST00000313599.3	CD163L1	CD163 molecule-like 1
chr5_+_140792614	0.17	ENST00000398610.2	PCDHGA10	protocadherin gamma subfamily A, 10
chr10_-_28623368	0.17	ENST00000441595.2	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_+_246729724	0.16	ENST00000366513.4 ENST00000366512.3	CNST	consortin, connexin sorting protein
chr14_+_88851874	0.16	ENST00000393545.4 ENST00000356583.5 ENST00000555401.1 ENST00000553885.1	SPATA7	spermatogenesis associated 7
chr2_-_32490859	0.16	ENST00000404025.2	NLRC4	NLR family, CARD domain containing 4
chr6_+_161123270	0.16	ENST00000366924.2 ENST00000308192.9 ENST00000418964.1	PLG	plasminogen
chr5_-_131132658	0.16	ENST00000514667.1 ENST00000511848.1 ENST00000510461.1	CTC-432M15.3 FNIP1	Folliculin-interacting protein 1 folliculin interacting protein 1
chr2_+_54342574	0.16	ENST00000303536.4 ENST00000394666.3	ACYP2	acylphosphatase 2, muscle type
chr2_+_74120094	0.16	ENST00000409731.3 ENST00000345517.3 ENST00000409918.1 ENST00000442912.1 ENST00000409624.1	ACTG2	actin, gamma 2, smooth muscle, enteric
chr9_-_116163400	0.16	ENST00000277315.5 ENST00000448137.1 ENST00000409155.3	ALAD	aminolevulinate dehydratase
chr20_-_30311703	0.16	ENST00000450273.1 ENST00000456404.1 ENST00000420488.1 ENST00000439267.1	BCL2L1	BCL2-like 1
chr2_+_61372226	0.16	ENST00000426997.1	C2orf74	chromosome 2 open reading frame 74
chr20_+_56964169	0.15	ENST00000475243.1	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr3_-_58523010	0.15	ENST00000459701.2 ENST00000302819.5	ACOX2	acyl-CoA oxidase 2, branched chain
chr3_-_105588231	0.15	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr5_+_147774275	0.15	ENST00000513826.1	FBXO38	F-box protein 38
chr3_-_127455200	0.15	ENST00000398101.3	MGLL	monoglyceride lipase
chr1_+_174844645	0.15	ENST00000486220.1	RABGAP1L	RAB GTPase activating protein 1-like
chr10_-_49482907	0.15	ENST00000374201.3 ENST00000407470.4	FRMPD2	FERM and PDZ domain containing 2
chr5_-_153418407	0.15	ENST00000522858.1 ENST00000522634.1 ENST00000523705.1 ENST00000524246.1 ENST00000520313.1 ENST00000518102.1 ENST00000351797.4 ENST00000520667.1 ENST00000519808.1 ENST00000522395.1	FAM114A2	family with sequence similarity 114, member A2
chr1_-_241803679	0.15	ENST00000331838.5	OPN3	opsin 3
chr20_+_33104199	0.15	ENST00000357156.2 ENST00000417166.2 ENST00000300469.9 ENST00000374846.3	DYNLRB1	dynein, light chain, roadblock-type 1
chr12_-_49582978	0.15	ENST00000301071.7	TUBA1A	tubulin, alpha 1a
chrX_+_153455547	0.14	ENST00000430054.1	OPN1MW	opsin 1 (cone pigments), medium-wave-sensitive
chr15_-_40600026	0.14	ENST00000456256.2 ENST00000557821.1	PLCB2	phospholipase C, beta 2
chr1_-_149982624	0.14	ENST00000417191.1 ENST00000369135.4	OTUD7B	OTU domain containing 7B
chr1_-_241803649	0.14	ENST00000366554.2	OPN3	opsin 3
chr22_-_43036607	0.14	ENST00000505920.1	ATP5L2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr7_-_6098770	0.14	ENST00000536084.1 ENST00000446699.1 ENST00000199389.6	EIF2AK1	eukaryotic translation initiation factor 2-alpha kinase 1
chr4_+_88754069	0.14	ENST00000395102.4 ENST00000497649.2	MEPE	matrix extracellular phosphoglycoprotein
chr9_-_70490107	0.14	ENST00000377395.4 ENST00000429800.2 ENST00000430059.2 ENST00000377384.1 ENST00000382405.3	CBWD5	COBW domain containing 5
chr19_+_36630454	0.14	ENST00000246533.3	CAPNS1	calpain, small subunit 1
chrX_-_47863348	0.14	ENST00000376943.3 ENST00000396965.1 ENST00000305127.6	ZNF182	zinc finger protein 182
chr19_+_18208603	0.13	ENST00000262811.6	MAST3	microtubule associated serine/threonine kinase 3
chr17_+_71229346	0.13	ENST00000535032.2 ENST00000582793.1	C17orf80	chromosome 17 open reading frame 80
chr3_+_180319918	0.13	ENST00000296015.4 ENST00000491380.1 ENST00000412756.2 ENST00000382584.4	TTC14	tetratricopeptide repeat domain 14
chrX_+_16668278	0.13	ENST00000380200.3	S100G	S100 calcium binding protein G
chr3_-_151102529	0.13	ENST00000302632.3	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr1_+_26036093	0.13	ENST00000374329.1	MAN1C1	mannosidase, alpha, class 1C, member 1
chr11_-_26593649	0.13	ENST00000455601.2	MUC15	mucin 15, cell surface associated
chr4_-_76928641	0.13	ENST00000264888.5	CXCL9	chemokine (C-X-C motif) ligand 9
chr7_-_144435985	0.13	ENST00000549981.1	TPK1	thiamin pyrophosphokinase 1
chr6_+_168418553	0.13	ENST00000354419.2 ENST00000351261.3	KIF25	kinesin family member 25
chr4_-_140223614	0.12	ENST00000394223.1	NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr14_+_105267250	0.12	ENST00000342537.7	ZBTB42	zinc finger and BTB domain containing 42
chr13_-_103346854	0.12	ENST00000267273.6	METTL21C	methyltransferase like 21C
chr19_+_57640011	0.12	ENST00000598197.1	USP29	ubiquitin specific peptidase 29
chr11_-_9286921	0.12	ENST00000328194.3	DENND5A	DENN/MADD domain containing 5A
chr19_-_52255107	0.12	ENST00000595042.1 ENST00000304748.4	FPR1	formyl peptide receptor 1
chr9_-_86432547	0.12	ENST00000376365.3 ENST00000376371.2	GKAP1	G kinase anchoring protein 1
chr17_-_39183452	0.12	ENST00000361883.5	KRTAP1-5	keratin associated protein 1-5
chr8_+_26247878	0.12	ENST00000518611.1	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr3_+_119316689	0.12	ENST00000273371.4	PLA1A	phospholipase A1 member A
chr12_-_76462713	0.12	ENST00000552056.1	NAP1L1	nucleosome assembly protein 1-like 1
chr3_-_169487617	0.12	ENST00000330368.2	ACTRT3	actin-related protein T3
chr8_-_145754428	0.11	ENST00000527462.1 ENST00000313465.5 ENST00000524821.1	C8orf82	chromosome 8 open reading frame 82
chr4_-_70826725	0.11	ENST00000353151.3	CSN2	casein beta
chr19_-_36523709	0.11	ENST00000592017.1 ENST00000360535.4	CLIP3	CAP-GLY domain containing linker protein 3
chr11_-_47447767	0.11	ENST00000530651.1 ENST00000524447.2 ENST00000531051.2 ENST00000526993.1 ENST00000602866.1	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr5_-_137674000	0.11	ENST00000510119.1 ENST00000513970.1	CDC25C	cell division cycle 25C
chr1_-_43855479	0.11	ENST00000290663.6 ENST00000372457.4	MED8	mediator complex subunit 8
chr20_+_48552908	0.11	ENST00000244061.2	RNF114	ring finger protein 114
chr16_+_28858004	0.11	ENST00000322610.8	SH2B1	SH2B adaptor protein 1
chr8_+_100025476	0.11	ENST00000355155.1 ENST00000357162.2 ENST00000358544.2 ENST00000395996.1 ENST00000441350.2	VPS13B	vacuolar protein sorting 13 homolog B (yeast)
chr19_-_40732594	0.11	ENST00000430325.2 ENST00000433940.1	CNTD2	cyclin N-terminal domain containing 2
chr10_+_52152766	0.11	ENST00000596442.1	AC069547.2	Uncharacterized protein
chr11_-_47447970	0.11	ENST00000298852.3 ENST00000530912.1	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr2_-_3521518	0.11	ENST00000382093.5	ADI1	acireductone dioxygenase 1
chr4_-_170679024	0.11	ENST00000393381.2	C4orf27	chromosome 4 open reading frame 27
chr21_+_40817749	0.11	ENST00000380637.3 ENST00000380634.1 ENST00000458295.1 ENST00000440288.2 ENST00000380631.1	SH3BGR	SH3 domain binding glutamic acid-rich protein
chr7_-_14028488	0.11	ENST00000405358.4	ETV1	ets variant 1
chr17_-_7531121	0.11	ENST00000573566.1 ENST00000269298.5	SAT2	spermidine/spermine N1-acetyltransferase family member 2
chr1_+_84609944	0.11	ENST00000370685.3	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr3_+_119316721	0.10	ENST00000488919.1 ENST00000495992.1	PLA1A	phospholipase A1 member A
chr1_+_196621002	0.10	ENST00000367429.4 ENST00000439155.2	CFH	complement factor H
chr20_+_48429233	0.10	ENST00000417961.1	SLC9A8	solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr12_-_76879852	0.10	ENST00000548341.1	OSBPL8	oxysterol binding protein-like 8
chr6_-_161085291	0.10	ENST00000316300.5	LPA	lipoprotein, Lp(a)
chr9_-_13175823	0.10	ENST00000545857.1	MPDZ	multiple PDZ domain protein
chr1_+_161123536	0.10	ENST00000368003.5	UFC1	ubiquitin-fold modifier conjugating enzyme 1
chr1_-_169555779	0.10	ENST00000367797.3 ENST00000367796.3	F5	coagulation factor V (proaccelerin, labile factor)
chr8_-_100025238	0.10	ENST00000521696.1	RP11-410L14.2	RP11-410L14.2
chr1_-_16763685	0.10	ENST00000540400.1	SPATA21	spermatogenesis associated 21
chr7_-_38389573	0.10	ENST00000390344.2	TRGV5	T cell receptor gamma variable 5

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.3	1.0	GO:0070428	negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2	0.9	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2	2.8	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	0.7	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2	0.7	GO:0007509	mesoderm migration involved in gastrulation(GO:0007509)
0.2	0.5	GO:0046113	purine nucleobase catabolic process(GO:0006145) xanthine metabolic process(GO:0046110) nucleobase catabolic process(GO:0046113)
0.2	0.5	GO:0032764	negative regulation of mast cell cytokine production(GO:0032764)
0.1	0.5	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.7	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.6	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.4	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.1	0.3	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.3	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.1	2.1	GO:0001502	cartilage condensation(GO:0001502)
0.1	1.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.1	0.6	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1	0.5	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.8	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.1	0.3	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.6	GO:0016139	glycoside catabolic process(GO:0016139)
0.1	0.2	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1	0.2	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	0.2	GO:0070541	response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.1	0.4	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.6	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.3	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.5	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.0	0.3	GO:2000332	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	0.1	GO:1903487	regulation of lactation(GO:1903487)
0.0	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.2	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.0	0.6	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0003363	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0	0.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.4	GO:0051451	myoblast migration(GO:0051451)
0.0	0.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.4	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.9	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.5	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	1.4	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.2	GO:0090131	mesenchyme migration(GO:0090131)
0.0	0.2	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0009447	putrescine catabolic process(GO:0009447)
0.0	0.2	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0015993	molecular hydrogen transport(GO:0015993)
0.0	0.2	GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0	0.1	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.9	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	1.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0019557	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0	0.2	GO:0072423	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0	0.1	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.1	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.1	GO:0032571	response to vitamin K(GO:0032571)
0.0	0.1	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.2	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:1903509	glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)
0.0	0.1	GO:0097338	response to clozapine(GO:0097338)
0.0	0.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	0.2	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.5	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.1	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.1	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.1	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0	0.1	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.2	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.0	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.0	2.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.3	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.1	GO:0035701	immunoglobulin biosynthetic process(GO:0002378) negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) hematopoietic stem cell migration(GO:0035701)
0.0	0.3	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.1	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.4	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0034238	macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0	0.2	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.4	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.3	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0	0.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:1902636	kinociliary basal body(GO:1902636)
0.2	2.8	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.4	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	0.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	0.3	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.8	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0043293	apoptosome(GO:0043293)
0.0	0.4	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.4	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.5	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0008091	spectrin(GO:0008091)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.2	0.6	GO:0004560	alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2	0.8	GO:0002046	opsin binding(GO:0002046)
0.1	0.6	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	0.5	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	0.8	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.4	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.1	0.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.6	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.9	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.5	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.2	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1	0.2	GO:0033149	FFAT motif binding(GO:0033149)
0.1	0.3	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.2	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.3	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.3	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.5	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.0	0.1	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	3.9	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0	0.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.9	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.5	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.5	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.3	GO:0043426	MRF binding(GO:0043426)
0.0	0.8	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.2	GO:0097001	ceramide binding(GO:0097001)
0.0	0.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.3	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0042731	PH domain binding(GO:0042731)
0.0	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.1	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.4	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.2	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.8	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0032052	bile acid binding(GO:0032052)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.4	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	1.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.6	GO:0030331	estrogen receptor binding(GO:0030331)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.7	PID ARF6 PATHWAY	Arf6 signaling events
0.0	1.0	PID ILK PATHWAY	Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	2.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.5	REACTOME OPSINS	Genes involved in Opsins
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes