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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 1.54

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Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
FOXD1
ENSG00000251493.2 FOXD1
FOXO1
ENSG00000150907.6 FOXO1
FOXO6
ENSG00000204060.4 FOXO6
FOXG1
ENSG00000176165.7 FOXG1
FOXP1
ENSG00000114861.14 FOXP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO6hg19_v2_chr1_+_41827594_418275940.581.4e-01Click!
FOXD1hg19_v2_chr5_-_72744336_72744359-0.561.5e-01Click!
FOXO1hg19_v2_chr13_-_41240717_412407350.502.1e-01Click!
FOXG1hg19_v2_chr14_+_29236269_29236287,
hg19_v2_chr14_+_29234870_29235050		-0.265.3e-01Click!
FOXP1hg19_v2_chr3_-_71632894_71632909-0.245.6e-01Click!

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_111985713 2.61 ENST00000239007.7
 MXI1
 MAX interactor 1, dimerization protein
chr17_+_58755184 1.83 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
 BCAS3
 breast carcinoma amplified sequence 3
chr2_+_42104692 1.69 ENST00000398796.2
ENST00000442214.1
 AC104654.1
 AC104654.1
chr16_-_30107491 1.63 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
 YPEL3
 yippee-like 3 (Drosophila)
chr6_+_89791507 1.63 ENST00000354922.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr18_+_66465302 1.34 ENST00000360242.5
ENST00000358653.5
 CCDC102B
 coiled-coil domain containing 102B
chr7_+_106809406 1.21 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
 HBP1
 HMG-box transcription factor 1
chr1_+_145438469 1.18 ENST00000369317.4
 TXNIP
 thioredoxin interacting protein
chr3_-_114477787 1.15 ENST00000464560.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr12_-_92539614 1.12 ENST00000256015.3
 BTG1
 B-cell translocation gene 1, anti-proliferative
chr17_+_57408994 1.09 ENST00000312655.4
 YPEL2
 yippee-like 2 (Drosophila)
chrX_+_135251835 1.08 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr11_-_111781554 0.96 ENST00000526167.1
ENST00000528961.1
 CRYAB
 crystallin, alpha B
chr7_-_112579869 0.96 ENST00000297145.4
 C7orf60
 chromosome 7 open reading frame 60
chr10_+_23728198 0.95 ENST00000376495.3
 OTUD1
 OTU domain containing 1
chrX_+_135251783 0.94 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr11_-_72504681 0.93 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr22_-_31688381 0.92 ENST00000487265.2
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr6_+_72922590 0.92 ENST00000523963.1
 RIMS1
 regulating synaptic membrane exocytosis 1
chr6_+_72922505 0.91 ENST00000401910.3
 RIMS1
 regulating synaptic membrane exocytosis 1
chr11_-_111781610 0.90 ENST00000525823.1
 CRYAB
 crystallin, alpha B
chr6_-_88875654 0.89 ENST00000535130.1
 CNR1
 cannabinoid receptor 1 (brain)
chr7_+_30174426 0.89 ENST00000324453.8
 C7orf41
 maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr11_-_111781454 0.88 ENST00000533280.1
 CRYAB
 crystallin, alpha B
chr17_-_26662464 0.88 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chrX_-_106960285 0.86 ENST00000503515.1
ENST00000372397.2
 TSC22D3
 TSC22 domain family, member 3
chr9_+_118916082 0.85 ENST00000328252.3
 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
chr19_+_18496957 0.81 ENST00000252809.3
 GDF15
 growth differentiation factor 15
chr3_-_141868293 0.81 ENST00000317104.7
ENST00000494358.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr17_-_26662440 0.80 ENST00000578122.1
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr3_-_18466026 0.78 ENST00000417717.2
 SATB1
 SATB homeobox 1
chr9_-_98269481 0.78 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
 PTCH1
 patched 1
chr14_+_24584508 0.78 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
 DCAF11
 DDB1 and CUL4 associated factor 11
chr3_-_114477962 0.77 ENST00000471418.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr14_-_74551096 0.77 ENST00000350259.4
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr14_+_24583836 0.77 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
 DCAF11
 DDB1 and CUL4 associated factor 11
chr10_+_99079008 0.76 ENST00000371021.3
 FRAT1
 frequently rearranged in advanced T-cell lymphomas
chr5_+_78532003 0.74 ENST00000396137.4
 JMY
 junction mediating and regulatory protein, p53 cofactor
chr19_-_47734448 0.74 ENST00000439096.2
 BBC3
 BCL2 binding component 3
chr1_+_33722080 0.73 ENST00000483388.1
ENST00000539719.1
 ZNF362
 zinc finger protein 362
chr13_-_41240717 0.72 ENST00000379561.5
 FOXO1
 forkhead box O1
chr19_+_12902289 0.69 ENST00000302754.4
 JUNB
 jun B proto-oncogene
chr22_-_31688431 0.66 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr7_-_150946015 0.65 ENST00000262188.8
 SMARCD3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr14_+_23067146 0.64 ENST00000428304.2
 ABHD4
 abhydrolase domain containing 4
chr3_-_141868357 0.64 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_36301984 0.64 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
 RANBP3L
 RAN binding protein 3-like
chrX_+_135252050 0.62 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chr15_-_31283618 0.62 ENST00000563714.1
 MTMR10
 myotubularin related protein 10
chr6_+_139094657 0.61 ENST00000332797.6
 CCDC28A
 coiled-coil domain containing 28A
chr2_+_86947296 0.59 ENST00000283632.4
 RMND5A
 required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr1_+_227127981 0.58 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
 ADCK3
 aarF domain containing kinase 3
chr17_+_38333263 0.58 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
 RAPGEFL1
 Rap guanine nucleotide exchange factor (GEF)-like 1
chr4_-_152149033 0.56 ENST00000514152.1
 SH3D19
 SH3 domain containing 19
chr22_-_37505449 0.55 ENST00000406725.1
 TMPRSS6
 transmembrane protease, serine 6
chr11_-_34535332 0.54 ENST00000257832.2
ENST00000429939.2
 ELF5
 E74-like factor 5 (ets domain transcription factor)
chr13_-_67802549 0.53 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr15_-_83240507 0.52 ENST00000564522.1
ENST00000398592.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr22_-_37505588 0.51 ENST00000406856.1
 TMPRSS6
 transmembrane protease, serine 6
chr4_-_147043058 0.51 ENST00000512063.1
ENST00000507726.1
 RP11-6L6.3
 long intergenic non-protein coding RNA 1095
chr17_-_19290483 0.51 ENST00000395592.2
ENST00000299610.4
 MFAP4
 microfibrillar-associated protein 4
chr9_-_88897426 0.50 ENST00000375991.4
ENST00000326094.4
 ISCA1
 iron-sulfur cluster assembly 1
chr19_+_50380682 0.50 ENST00000221543.5
 TBC1D17
 TBC1 domain family, member 17
chr8_+_99956662 0.50 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
 OSR2
 odd-skipped related transciption factor 2
chr4_-_140223614 0.48 ENST00000394223.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr4_-_186696425 0.48 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr18_+_3449330 0.48 ENST00000549253.1
 TGIF1
 TGFB-induced factor homeobox 1
chr8_-_124553437 0.48 ENST00000517956.1
ENST00000443022.2
 FBXO32
 F-box protein 32
chr2_+_12857043 0.48 ENST00000381465.2
 TRIB2
 tribbles pseudokinase 2
chr2_+_12857015 0.47 ENST00000155926.4
 TRIB2
 tribbles pseudokinase 2
chr19_+_50380917 0.46 ENST00000535102.2
 TBC1D17
 TBC1 domain family, member 17
chr3_+_159570722 0.46 ENST00000482804.1
 SCHIP1
 schwannomin interacting protein 1
chr17_+_39394250 0.46 ENST00000254072.6
 KRTAP9-8
 keratin associated protein 9-8
chr9_-_84303269 0.45 ENST00000418319.1
 TLE1
 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr1_-_201096312 0.45 ENST00000449188.2
 ASCL5
 achaete-scute family bHLH transcription factor 5
chr6_-_32122106 0.45 ENST00000428778.1
 PRRT1
 proline-rich transmembrane protein 1
chr2_-_176032843 0.45 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
 ATF2
 activating transcription factor 2
chr14_-_74551172 0.43 ENST00000553458.1
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr2_-_74007193 0.43 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
 DUSP11
 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr12_+_12764773 0.42 ENST00000228865.2
 CREBL2
 cAMP responsive element binding protein-like 2
chr16_-_4665023 0.42 ENST00000591897.1
 UBALD1
 UBA-like domain containing 1
chr4_-_140223670 0.42 ENST00000394228.1
ENST00000539387.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr1_+_87797351 0.42 ENST00000370542.1
 LMO4
 LIM domain only 4
chr1_-_45956822 0.41 ENST00000372086.3
ENST00000341771.6
 TESK2
 testis-specific kinase 2
chr20_+_44035200 0.41 ENST00000372717.1
ENST00000360981.4
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr17_+_57642886 0.41 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
 DHX40
 DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_+_86396265 0.41 ENST00000395184.1
 ARHGAP24
 Rho GTPase activating protein 24
chr8_+_52730143 0.41 ENST00000415643.1
 AC090186.1
 Uncharacterized protein
chr1_-_45956800 0.40 ENST00000538496.1
 TESK2
 testis-specific kinase 2
chr9_-_94124171 0.40 ENST00000422391.2
ENST00000375731.4
ENST00000303617.5
 AUH
 AU RNA binding protein/enoyl-CoA hydratase
chr1_+_229440129 0.40 ENST00000366688.3
 SPHAR
 S-phase response (cyclin related)
chr18_-_53257027 0.39 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
 TCF4
 transcription factor 4
chr20_-_1309809 0.38 ENST00000360779.3
 SDCBP2
 syndecan binding protein (syntenin) 2
chr16_-_4664860 0.38 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
 UBALD1
 UBA-like domain containing 1
chr4_-_141075330 0.38 ENST00000509479.2
 MAML3
 mastermind-like 3 (Drosophila)
chr6_-_30043539 0.38 ENST00000376751.3
ENST00000244360.6
 RNF39
 ring finger protein 39
chr1_-_160231451 0.38 ENST00000495887.1
 DCAF8
 DDB1 and CUL4 associated factor 8
chr2_+_163175394 0.38 ENST00000446271.1
ENST00000429691.2
 GCA
 grancalcin, EF-hand calcium binding protein
chr3_+_193853927 0.38 ENST00000232424.3
 HES1
 hes family bHLH transcription factor 1
chr12_-_53343602 0.37 ENST00000546897.1
ENST00000552551.1
 KRT8
 keratin 8
chr2_-_27294500 0.37 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
 OST4
 oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr14_-_73493784 0.37 ENST00000553891.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chrX_-_48937503 0.37 ENST00000322995.8
 WDR45
 WD repeat domain 45
chr20_+_44035847 0.37 ENST00000372712.2
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_+_148447887 0.37 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
 AGTR1
 angiotensin II receptor, type 1
chr6_+_125540951 0.36 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chrX_+_70316005 0.36 ENST00000374259.3
 FOXO4
 forkhead box O4
chr2_+_33661382 0.36 ENST00000402538.3
 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_-_65569244 0.36 ENST00000557277.1
ENST00000556892.1
 MAX
 MYC associated factor X
chr11_-_72504637 0.35 ENST00000536377.1
ENST00000359373.5
 STARD10
ARAP1
 StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr8_+_70404996 0.35 ENST00000402687.4
ENST00000419716.3
 SULF1
 sulfatase 1
chr6_-_42016385 0.35 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
 CCND3
 cyclin D3
chr11_+_33061543 0.34 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
 TCP11L1
 t-complex 11, testis-specific-like 1
chr5_-_64920115 0.34 ENST00000381018.3
ENST00000274327.7
 TRIM23
 tripartite motif containing 23
chr21_+_17442799 0.34 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr14_-_65569057 0.34 ENST00000555419.1
ENST00000341653.2
 MAX
 MYC associated factor X
chr10_-_90751038 0.34 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr1_-_161102367 0.34 ENST00000464113.1
 DEDD
 death effector domain containing
chr10_-_49482907 0.33 ENST00000374201.3
ENST00000407470.4
 FRMPD2
 FERM and PDZ domain containing 2
chr17_+_67410832 0.33 ENST00000590474.1
 MAP2K6
 mitogen-activated protein kinase kinase 6
chr12_-_15038779 0.33 ENST00000228938.5
ENST00000539261.1
 MGP
 matrix Gla protein
chr9_-_98279241 0.33 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
 PTCH1
 patched 1
chr17_-_39165366 0.33 ENST00000391588.1
 KRTAP3-1
 keratin associated protein 3-1
chr12_+_100867694 0.32 ENST00000392986.3
ENST00000549996.1
 NR1H4
 nuclear receptor subfamily 1, group H, member 4
chr3_-_178789220 0.32 ENST00000414084.1
 ZMAT3
 zinc finger, matrin-type 3
chr19_-_18391708 0.32 ENST00000600972.1
 JUND
 jun D proto-oncogene
chr21_-_35899113 0.31 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
 RCAN1
 regulator of calcineurin 1
chr6_+_136172820 0.31 ENST00000308191.6
 PDE7B
 phosphodiesterase 7B
chr4_+_86396321 0.31 ENST00000503995.1
 ARHGAP24
 Rho GTPase activating protein 24
chr16_+_29823552 0.30 ENST00000300797.6
 PRRT2
 proline-rich transmembrane protein 2
chr4_-_186733363 0.30 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2
chr3_-_178789993 0.30 ENST00000432729.1
 ZMAT3
 zinc finger, matrin-type 3
chr8_-_72274467 0.30 ENST00000340726.3
 EYA1
 eyes absent homolog 1 (Drosophila)
chr3_-_178790057 0.30 ENST00000311417.2
 ZMAT3
 zinc finger, matrin-type 3
chrX_-_48937531 0.30 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
 WDR45
AF196779.12
 WD repeat domain 45
WD repeat domain phosphoinositide-interacting protein 4
chr15_-_83240553 0.30 ENST00000423133.2
ENST00000398591.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr7_+_90339169 0.30 ENST00000436577.2
 CDK14
 cyclin-dependent kinase 14
chr21_+_30671690 0.29 ENST00000399921.1
 BACH1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_-_73493825 0.29 ENST00000318876.5
ENST00000556143.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr2_-_183387430 0.29 ENST00000410103.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr19_-_50380536 0.29 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
 AKT1S1
 AKT1 substrate 1 (proline-rich)
chr14_-_76447494 0.29 ENST00000238682.3
 TGFB3
 transforming growth factor, beta 3
chr1_+_65730385 0.29 ENST00000263441.7
ENST00000395325.3
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_-_57233966 0.29 ENST00000473921.1
ENST00000295934.3
 HESX1
 HESX homeobox 1
chr1_+_3541543 0.29 ENST00000378344.2
ENST00000344579.5
 TPRG1L
 tumor protein p63 regulated 1-like
chr1_-_161102421 0.29 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
 DEDD
 death effector domain containing
chr18_-_53070913 0.28 ENST00000568186.1
ENST00000564228.1
 TCF4
 transcription factor 4
chr9_-_101558777 0.28 ENST00000375018.1
ENST00000353234.4
 ANKS6
 ankyrin repeat and sterile alpha motif domain containing 6
chr5_+_121465207 0.28 ENST00000296600.4
 ZNF474
 zinc finger protein 474
chr3_-_114866084 0.28 ENST00000357258.3
 ZBTB20
 zinc finger and BTB domain containing 20
chr2_-_26205340 0.28 ENST00000264712.3
 KIF3C
 kinesin family member 3C
chr11_-_102826434 0.28 ENST00000340273.4
ENST00000260302.3
 MMP13
 matrix metallopeptidase 13 (collagenase 3)
chr15_-_63449663 0.28 ENST00000439025.1
 RPS27L
 ribosomal protein S27-like
chr7_+_129007964 0.28 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
 AHCYL2
 adenosylhomocysteinase-like 2
chr8_-_72274095 0.28 ENST00000303824.7
 EYA1
 eyes absent homolog 1 (Drosophila)
chr8_-_93107443 0.28 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_172483347 0.28 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
 CREBRF
 CREB3 regulatory factor
chr20_-_22559211 0.28 ENST00000564492.1
 LINC00261
 long intergenic non-protein coding RNA 261
chr2_-_69098566 0.28 ENST00000295379.1
 BMP10
 bone morphogenetic protein 10
chr2_+_111878483 0.28 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
 BCL2L11
 BCL2-like 11 (apoptosis facilitator)
chr6_+_84563295 0.27 ENST00000369687.1
 RIPPLY2
 ripply transcriptional repressor 2
chr20_+_306177 0.27 ENST00000544632.1
 SOX12
 SRY (sex determining region Y)-box 12
chr17_+_26662730 0.27 ENST00000226225.2
 TNFAIP1
 tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr10_+_99400443 0.27 ENST00000370631.3
 PI4K2A
 phosphatidylinositol 4-kinase type 2 alpha
chr12_+_120740119 0.26 ENST00000536460.1
ENST00000202967.4
 SIRT4
 sirtuin 4
chr9_-_3525968 0.26 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3
 regulatory factor X, 3 (influences HLA class II expression)
chr6_-_33168391 0.26 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
 RXRB
 retinoid X receptor, beta
chr20_-_44519839 0.26 ENST00000372518.4
 NEURL2
 neuralized E3 ubiquitin protein ligase 2
chr19_-_18902106 0.26 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
 COMP
 cartilage oligomeric matrix protein
chr14_-_65569186 0.26 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
 MAX
 MYC associated factor X
chr12_-_56352368 0.26 ENST00000549404.1
 PMEL
 premelanosome protein
chr1_+_164529004 0.25 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
 PBX1
 pre-B-cell leukemia homeobox 1
chr14_-_103987679 0.25 ENST00000553610.1
 CKB
 creatine kinase, brain
chr3_+_54157480 0.25 ENST00000490478.1
 CACNA2D3
 calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr5_-_150460539 0.25 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
 TNIP1
 TNFAIP3 interacting protein 1
chr12_-_71551868 0.25 ENST00000247829.3
 TSPAN8
 tetraspanin 8
chr3_-_114343039 0.24 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr2_-_121223697 0.24 ENST00000593290.1
 FLJ14816
 long intergenic non-protein coding RNA 1101
chr10_-_91403625 0.24 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
 PANK1
 pantothenate kinase 1
chr10_-_99094458 0.24 ENST00000371019.2
 FRAT2
 frequently rearranged in advanced T-cell lymphomas 2
chr12_-_71551652 0.24 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr19_+_1205740 0.24 ENST00000326873.7
 STK11
 serine/threonine kinase 11
chr12_+_54378923 0.23 ENST00000303460.4
 HOXC10
 homeobox C10
chr14_+_50234827 0.23 ENST00000554589.1
ENST00000557247.1
 KLHDC2
 kelch domain containing 2
chr16_+_86612112 0.23 ENST00000320241.3
 FOXL1
 forkhead box L1
chr1_-_1356719 0.23 ENST00000520296.1
 ANKRD65
 ankyrin repeat domain 65
chr1_-_27816641 0.23 ENST00000430629.2
 WASF2
 WAS protein family, member 2
chr15_+_81589254 0.23 ENST00000394652.2
 IL16
 interleukin 16
chr11_-_119999539 0.23 ENST00000541857.1
 TRIM29
 tripartite motif containing 29
chr8_-_80993010 0.23 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
 TPD52
 tumor protein D52
chr11_-_119999611 0.23 ENST00000529044.1
 TRIM29
 tripartite motif containing 29
chr1_-_161102213 0.23 ENST00000458050.2
 DEDD
 death effector domain containing
chr1_-_1356628 0.23 ENST00000442470.1
ENST00000537107.1
 ANKRD65
 ankyrin repeat domain 65
chr17_+_74261277 0.22 ENST00000327490.6
 UBALD2
 UBA-like domain containing 2
chr2_-_68547061 0.22 ENST00000263655.3
 CNRIP1
 cannabinoid receptor interacting protein 1
chr10_+_95848824 0.22 ENST00000371385.3
ENST00000371375.1
 PLCE1
 phospholipase C, epsilon 1
chr5_-_40755987 0.22 ENST00000337702.4
 TTC33
 tetratricopeptide repeat domain 33
chr6_+_108977520 0.22 ENST00000540898.1
 FOXO3
 forkhead box O3
chr18_+_56530136 0.22 ENST00000591083.1
 ZNF532
 zinc finger protein 532
chr10_+_74033672 0.22 ENST00000307365.3
 DDIT4
 DNA-damage-inducible transcript 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.9 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.9 GO:0010157 response to chlorate(GO:0010157)
0.2 0.9 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.6 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.4 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 1.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.5 GO:0061045 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.2 2.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.7 GO:1902617 response to fluoride(GO:1902617)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.9 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.7 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.3 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 2.7 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.4 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.2 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.5 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.7 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.8 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 2.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 1.0 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.2 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.4 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0072185 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.6 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.2 GO:2000468 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0070884 calcineurin-NFAT signaling cascade(GO:0033173) regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0009415 response to water(GO:0009415)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of JNK cascade(GO:0046330) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.0 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0051198 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.3 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.4 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0043584 nose development(GO:0043584)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 1.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860) regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.8 GO:0048678 response to axon injury(GO:0048678)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.6 GO:0034657 GID complex(GO:0034657)
0.2 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 2.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 1.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.4 GO:0036398 TCR signalosome(GO:0036398)
0.1 1.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0035838 growing cell tip(GO:0035838)
0.1 0.5 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 2.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 6.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.0 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.0 GO:0032044 DSIF complex(GO:0032044)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.8 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.7 GO:0002046 opsin binding(GO:0002046)
0.2 0.6 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.9 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.9 GO:0005119 smoothened binding(GO:0005119)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.4 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.4 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 1.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 7.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 3.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID MYC PATHWAY C-MYC pathway
0.0 1.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects