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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOXD3_FOXI1_FOXF1

Z-value: 1.09

Motif logo

Transcription factors associated with FOXD3_FOXI1_FOXF1

Gene Symbol Gene ID Gene Info
ENSG00000187140.4 FOXD3
ENSG00000168269.7 FOXI1
ENSG00000103241.5 FOXF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXI1hg19_v2_chr5_+_169532896_1695329170.866.3e-03Click!
FOXF1hg19_v2_chr16_+_86544113_86544145-0.677.2e-02Click!
FOXD3hg19_v2_chr1_+_63788730_63788730-0.353.9e-01Click!

Activity profile of FOXD3_FOXI1_FOXF1 motif

Sorted Z-values of FOXD3_FOXI1_FOXF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_97597148 2.27 ENST00000521590.1
SDC2
syndecan 2
chr8_-_108510224 1.87 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr12_-_15038779 1.70 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr17_-_19290483 1.50 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr1_-_57045228 1.32 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr18_-_52626622 1.21 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr14_-_92414055 1.17 ENST00000342058.4
FBLN5
fibulin 5
chr4_-_186696425 1.11 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr9_-_95244781 0.96 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr8_+_104384616 0.93 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr3_-_114343039 0.87 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_111781610 0.86 ENST00000525823.1
CRYAB
crystallin, alpha B
chr5_-_111091948 0.80 ENST00000447165.2
NREP
neuronal regeneration related protein
chr9_-_89562104 0.73 ENST00000298743.7
GAS1
growth arrest-specific 1
chr17_+_57408994 0.72 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr11_-_111781554 0.70 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chrX_+_22050546 0.69 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr11_-_111781454 0.69 ENST00000533280.1
CRYAB
crystallin, alpha B
chr5_+_32788945 0.68 ENST00000326958.1
AC026703.1
AC026703.1
chr5_-_172198190 0.68 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr3_+_45067659 0.66 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chrX_+_66764375 0.66 ENST00000374690.3
AR
androgen receptor
chr3_-_195310802 0.65 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr12_-_92539614 0.64 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_-_120685608 0.63 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr8_+_104383728 0.63 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr2_+_166095898 0.60 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr6_+_101846664 0.60 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr12_-_91576561 0.60 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chr4_+_124317940 0.60 ENST00000505319.1
ENST00000339241.1
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_+_97506033 0.58 ENST00000518385.1
SDC2
syndecan 2
chr2_-_72374948 0.57 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr1_+_159141397 0.57 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr2_+_128175997 0.54 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr5_-_19988339 0.54 ENST00000382275.1
CDH18
cadherin 18, type 2
chr18_-_56296182 0.52 ENST00000361673.3
ALPK2
alpha-kinase 2
chrX_+_16964985 0.51 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr3_-_114035026 0.49 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr8_-_120651020 0.49 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_-_72566613 0.48 ENST00000306821.3
NEGR1
neuronal growth regulator 1
chr8_+_75736761 0.48 ENST00000260113.2
PI15
peptidase inhibitor 15
chr1_+_197886461 0.47 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
LHX9
LIM homeobox 9
chr2_-_175711133 0.46 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr3_-_186080012 0.45 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr11_+_63304273 0.44 ENST00000439013.2
ENST00000255688.3
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr12_-_91574142 0.43 ENST00000547937.1
DCN
decorin
chr1_+_223101757 0.43 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr5_-_20575959 0.42 ENST00000507958.1
CDH18
cadherin 18, type 2
chr5_+_119799927 0.42 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr3_+_99357319 0.41 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr8_+_79428539 0.41 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr6_+_136172820 0.41 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr1_+_164528866 0.41 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr2_+_33359646 0.40 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.40 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_152214098 0.40 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr9_-_95298314 0.40 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr17_-_66951474 0.39 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr3_-_16524357 0.39 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr2_-_152146385 0.38 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr3_+_69812877 0.38 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr6_-_154751629 0.37 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr8_-_93107443 0.37 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_175443943 0.37 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_+_164529004 0.37 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr7_+_134430212 0.37 ENST00000436461.2
CALD1
caldesmon 1
chr5_-_158526756 0.36 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr12_-_91576429 0.36 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr21_+_17792672 0.36 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr8_+_52730143 0.35 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr12_+_79439405 0.35 ENST00000552744.1
SYT1
synaptotagmin I
chr12_-_71551652 0.34 ENST00000546561.1
TSPAN8
tetraspanin 8
chr11_+_64085560 0.34 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5
peroxiredoxin 5
chr2_-_2334888 0.34 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr12_-_56106060 0.34 ENST00000452168.2
ITGA7
integrin, alpha 7
chr1_-_227505289 0.33 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr10_+_31610064 0.33 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr3_+_114012819 0.33 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr12_-_15374343 0.32 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr18_-_25616519 0.32 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr6_-_25830785 0.32 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr13_-_67802549 0.31 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr5_+_156712372 0.31 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_102826434 0.31 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr12_+_10365404 0.31 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_+_233497931 0.30 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr8_-_60031762 0.30 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr5_-_127674883 0.30 ENST00000507835.1
FBN2
fibrillin 2
chr1_+_150122034 0.30 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr1_-_19811132 0.30 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr5_-_158526693 0.30 ENST00000380654.4
EBF1
early B-cell factor 1
chr6_-_152489484 0.30 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_-_111093167 0.30 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr5_+_40841276 0.30 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr2_+_166150541 0.29 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr6_+_89790490 0.29 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr2_-_145275228 0.29 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chrX_+_100743031 0.29 ENST00000423738.3
ARMCX4
armadillo repeat containing, X-linked 4
chr4_+_74347400 0.28 ENST00000226355.3
AFM
afamin
chr6_-_152639479 0.28 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_1297157 0.28 ENST00000477278.2
MXRA8
matrix-remodelling associated 8
chr21_+_17791838 0.28 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_104159999 0.28 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr12_+_25348186 0.28 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr4_-_186732048 0.28 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr2_-_188419200 0.28 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr21_+_17791648 0.28 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr15_-_93632421 0.27 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr1_-_92371839 0.27 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr8_-_93107696 0.27 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_157154578 0.27 ENST00000295927.3
PTX3
pentraxin 3, long
chr1_+_207277590 0.27 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr4_+_129732467 0.27 ENST00000413543.2
PHF17
jade family PHD finger 1
chr17_+_79953310 0.27 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_+_151038850 0.27 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chrX_-_102531717 0.26 ENST00000372680.1
TCEAL5
transcription elongation factor A (SII)-like 5
chrX_+_22056165 0.26 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr6_-_88875654 0.26 ENST00000535130.1
CNR1
cannabinoid receptor 1 (brain)
chr21_+_30502806 0.26 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_+_171060018 0.26 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
FMO3
flavin containing monooxygenase 3
chr12_+_25348139 0.26 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr4_-_175443484 0.26 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr8_-_93107827 0.26 ENST00000520724.1
ENST00000518844.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_153599732 0.25 ENST00000392623.1
S100A13
S100 calcium binding protein A13
chr11_+_5710919 0.25 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr7_+_48211048 0.25 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr10_-_31288398 0.25 ENST00000538351.2
ZNF438
zinc finger protein 438
chr12_+_51318513 0.25 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr2_+_158114051 0.25 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr5_+_161495038 0.24 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_-_188419078 0.24 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_106054952 0.24 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr7_+_18535854 0.24 ENST00000401921.1
HDAC9
histone deacetylase 9
chr8_+_70404996 0.24 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr3_-_114477787 0.23 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr10_+_111967345 0.23 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr3_-_121379739 0.23 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr6_-_131291572 0.23 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_+_201994569 0.23 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr16_-_67260691 0.23 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr5_+_139027877 0.23 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr4_+_86396265 0.23 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr15_-_55657428 0.23 ENST00000568543.1
CCPG1
cell cycle progression 1
chr6_-_133084580 0.23 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2
vanin 2
chr3_-_165555200 0.23 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr9_-_20622478 0.23 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_92777606 0.22 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr1_+_162602244 0.22 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chrX_+_85969626 0.22 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr4_-_159094194 0.22 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr3_-_187454281 0.22 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr7_-_27142290 0.22 ENST00000222718.5
HOXA2
homeobox A2
chr7_+_7811992 0.22 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr6_+_89790459 0.22 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr4_+_38869298 0.21 ENST00000510213.1
ENST00000515037.1
FAM114A1
family with sequence similarity 114, member A1
chr3_+_141105705 0.21 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_-_175443788 0.21 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chrX_-_154493791 0.21 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr11_-_62323702 0.21 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr6_-_167276033 0.21 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_-_72274467 0.21 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_14029283 0.21 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr2_+_109223595 0.21 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_+_17206635 0.21 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr3_+_69812701 0.21 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr3_+_154797428 0.20 ENST00000460393.1
MME
membrane metallo-endopeptidase
chr1_+_59775752 0.20 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr6_-_117747015 0.20 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr5_+_140571902 0.20 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr6_+_72926145 0.20 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr21_-_28338732 0.20 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr5_+_145718587 0.20 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr10_+_95848824 0.20 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chrX_-_101410762 0.20 ENST00000543160.1
ENST00000333643.3
BEX5
brain expressed, X-linked 5
chr14_-_61190754 0.20 ENST00000216513.4
SIX4
SIX homeobox 4
chr16_+_4421841 0.20 ENST00000304735.3
VASN
vasorin
chrX_+_55744166 0.20 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr4_-_84035905 0.20 ENST00000311507.4
PLAC8
placenta-specific 8
chr7_+_134551583 0.20 ENST00000435928.1
CALD1
caldesmon 1
chr8_-_72274095 0.20 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr10_-_90712520 0.20 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr6_+_114178512 0.20 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr7_+_142985308 0.19 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr18_+_3449330 0.19 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chrX_+_55744228 0.19 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr17_-_67138015 0.19 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr5_-_140700322 0.19 ENST00000313368.5
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr15_-_52944231 0.19 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr19_-_39322299 0.19 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
ECH1
enoyl CoA hydratase 1, peroxisomal
chr12_-_10605929 0.19 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr12_-_22487618 0.19 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_-_102401469 0.19 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr8_-_12668962 0.19 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr12_+_59989791 0.18 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr5_-_133510456 0.18 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr8_-_13372253 0.18 ENST00000316609.5
DLC1
deleted in liver cancer 1
chr6_-_82462425 0.18 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr2_-_211168332 0.18 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr12_+_99038919 0.18 ENST00000551964.1
APAF1
apoptotic peptidase activating factor 1
chr3_+_152017924 0.18 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0008218 bioluminescence(GO:0008218)
0.2 1.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.7 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 1.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 0.7 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.9 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 0.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.3 GO:0060939 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.1 2.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.2 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.2 GO:1902725 skeletal muscle fiber differentiation(GO:0098528) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 1.6 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.1 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.5 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.4 GO:0001554 luteolysis(GO:0001554)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0046449 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.7 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.3 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.3 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0046324 regulation of glucose transport(GO:0010827) regulation of glucose import(GO:0046324)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.1 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.2 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.4 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.0 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010) negative regulation of glial cell proliferation(GO:0060253)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.2 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.0 GO:0050968 thermoception(GO:0050955) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.0 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0071953 elastic fiber(GO:0071953)
0.1 2.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.6 GO:0001652 granular component(GO:0001652)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0030425 dendrite(GO:0030425)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 0.8 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.1 0.3 GO:0033265 choline binding(GO:0033265)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0001026 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 3.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade