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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GAGGUAG

Z-value: 1.14

Motif logo

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miRNA associated with seed GAGGUAG

NamemiRBASE accession
hsa-let-7a-5p
MIMAT0000062
hsa-let-7b-5p
MIMAT0000063
hsa-let-7c-5p
MIMAT0000064
hsa-let-7d-5p
MIMAT0000065
hsa-let-7e-5p
MIMAT0000066
hsa-let-7f-5p
MIMAT0000067
hsa-let-7g-5p
MIMAT0000414
hsa-let-7i-5p
MIMAT0000415
hsa-miR-98-5p
MIMAT0000096
hsa-miR-4458
MIMAT0018980
hsa-miR-4500
MIMAT0019036

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_100027943 2.70 ENST00000260702.3
 LOXL4
 lysyl oxidase-like 4
chr1_-_242687676 1.12 ENST00000536534.2
 PLD5
 phospholipase D family, member 5
chr5_+_167181917 1.10 ENST00000519204.1
 TENM2
 teneurin transmembrane protein 2
chr3_-_69435224 0.99 ENST00000398540.3
 FRMD4B
 FERM domain containing 4B
chr12_+_72666407 0.96 ENST00000261180.4
 TRHDE
 thyrotropin-releasing hormone degrading enzyme
chr1_-_153363452 0.96 ENST00000368732.1
ENST00000368733.3
 S100A8
 S100 calcium binding protein A8
chr1_-_9189229 0.96 ENST00000377411.4
 GPR157
 G protein-coupled receptor 157
chr1_+_60280458 0.87 ENST00000455990.1
ENST00000371208.3
 HOOK1
 hook microtubule-tethering protein 1
chr8_+_28351707 0.87 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
 FZD3
 frizzled family receptor 3
chr12_-_85306594 0.86 ENST00000266682.5
 SLC6A15
 solute carrier family 6 (neutral amino acid transporter), member 15
chr1_-_28503693 0.83 ENST00000373857.3
 PTAFR
 platelet-activating factor receptor
chr20_+_6748311 0.83 ENST00000378827.4
 BMP2
 bone morphogenetic protein 2
chr2_-_27435125 0.81 ENST00000414408.1
ENST00000310574.3
 SLC5A6
 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr1_+_152486950 0.81 ENST00000368790.3
 CRCT1
 cysteine-rich C-terminal 1
chrX_+_37545012 0.81 ENST00000378616.3
 XK
 X-linked Kx blood group (McLeod syndrome)
chr19_-_51523275 0.79 ENST00000309958.3
 KLK10
 kallikrein-related peptidase 10
chr4_+_84457250 0.78 ENST00000395226.2
 AGPAT9
 1-acylglycerol-3-phosphate O-acyltransferase 9
chr2_+_198570081 0.77 ENST00000282276.6
 MARS2
 methionyl-tRNA synthetase 2, mitochondrial
chr6_+_138188551 0.73 ENST00000237289.4
ENST00000433680.1
 TNFAIP3
 tumor necrosis factor, alpha-induced protein 3
chr14_+_67999999 0.73 ENST00000329153.5
 PLEKHH1
 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr8_+_61591337 0.71 ENST00000423902.2
 CHD7
 chromodomain helicase DNA binding protein 7
chr22_-_39640756 0.70 ENST00000331163.6
 PDGFB
 platelet-derived growth factor beta polypeptide
chr18_-_47721447 0.70 ENST00000285039.7
 MYO5B
 myosin VB
chr5_+_148206156 0.68 ENST00000305988.4
 ADRB2
 adrenoceptor beta 2, surface
chr6_+_12290586 0.68 ENST00000379375.5
 EDN1
 endothelin 1
chr20_-_46415297 0.66 ENST00000467815.1
ENST00000359930.4
 SULF2
 sulfatase 2
chr1_-_228135599 0.65 ENST00000272164.5
 WNT9A
 wingless-type MMTV integration site family, member 9A
chr15_+_74833518 0.64 ENST00000346246.5
 ARID3B
 AT rich interactive domain 3B (BRIGHT-like)
chr11_+_76571911 0.62 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
 ACER3
 alkaline ceramidase 3
chr6_-_99797522 0.62 ENST00000389677.5
 FAXC
 failed axon connections homolog (Drosophila)
chr7_+_90032667 0.61 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
 CLDN12
 claudin 12
chr12_+_4382917 0.60 ENST00000261254.3
 CCND2
 cyclin D2
chr16_+_66914264 0.60 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
 PDP2
 pyruvate dehyrogenase phosphatase catalytic subunit 2
chr6_+_106546808 0.58 ENST00000369089.3
 PRDM1
 PR domain containing 1, with ZNF domain
chr4_+_56815102 0.57 ENST00000257287.4
 CEP135
 centrosomal protein 135kDa
chr9_+_116917807 0.56 ENST00000356083.3
 COL27A1
 collagen, type XXVII, alpha 1
chr17_+_8924837 0.55 ENST00000173229.2
 NTN1
 netrin 1
chr2_+_75061108 0.55 ENST00000290573.2
 HK2
 hexokinase 2
chr3_-_185216766 0.54 ENST00000296254.3
 TMEM41A
 transmembrane protein 41A
chr8_+_24772455 0.53 ENST00000433454.2
 NEFM
 neurofilament, medium polypeptide
chr2_+_148602058 0.53 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
 ACVR2A
 activin A receptor, type IIA
chr14_-_53162361 0.52 ENST00000395686.3
 ERO1L
 ERO1-like (S. cerevisiae)
chr8_-_122653630 0.51 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr3_-_48229846 0.49 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
 CDC25A
 cell division cycle 25A
chr8_+_74206829 0.48 ENST00000240285.5
 RDH10
 retinol dehydrogenase 10 (all-trans)
chr1_-_204380919 0.48 ENST00000367188.4
 PPP1R15B
 protein phosphatase 1, regulatory subunit 15B
chr16_-_17564738 0.48 ENST00000261381.6
 XYLT1
 xylosyltransferase I
chr2_+_70142189 0.48 ENST00000264444.2
 MXD1
 MAX dimerization protein 1
chr2_+_109335929 0.47 ENST00000283195.6
 RANBP2
 RAN binding protein 2
chr6_-_3457256 0.46 ENST00000436008.2
 SLC22A23
 solute carrier family 22, member 23
chr12_-_57472522 0.45 ENST00000379391.3
ENST00000300128.4
 TMEM194A
 transmembrane protein 194A
chr15_+_80987617 0.45 ENST00000258884.4
ENST00000558464.1
 ABHD17C
 abhydrolase domain containing 17C
chr1_+_19638788 0.45 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
 PQLC2
 PQ loop repeat containing 2
chr7_-_138666053 0.45 ENST00000440172.1
ENST00000422774.1
 KIAA1549
 KIAA1549
chr15_+_75498355 0.44 ENST00000567617.1
 C15orf39
 chromosome 15 open reading frame 39
chr1_+_160370344 0.44 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chrX_-_117250740 0.43 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
 KLHL13
 kelch-like family member 13
chr6_-_97285336 0.43 ENST00000229955.3
ENST00000417980.1
 GPR63
 G protein-coupled receptor 63
chr10_+_101419187 0.43 ENST00000370489.4
 ENTPD7
 ectonucleoside triphosphate diphosphohydrolase 7
chr7_+_107220422 0.42 ENST00000005259.4
 BCAP29
 B-cell receptor-associated protein 29
chr8_-_29208183 0.42 ENST00000240100.2
 DUSP4
 dual specificity phosphatase 4
chr10_-_70231639 0.42 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
 DNA2
 DNA replication helicase/nuclease 2
chr6_+_41606176 0.41 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
 MDFI
 MyoD family inhibitor
chrX_+_16804544 0.41 ENST00000380122.5
ENST00000398155.4
 TXLNG
 taxilin gamma
chr6_-_80657292 0.41 ENST00000369816.4
 ELOVL4
 ELOVL fatty acid elongase 4
chr4_-_170924888 0.41 ENST00000502832.1
ENST00000393704.3
 MFAP3L
 microfibrillar-associated protein 3-like
chr3_-_79068594 0.41 ENST00000436010.2
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_-_139726181 0.41 ENST00000507104.1
ENST00000230990.6
 HBEGF
 heparin-binding EGF-like growth factor
chr2_+_32390925 0.40 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
 SLC30A6
 solute carrier family 30 (zinc transporter), member 6
chr12_+_88536067 0.39 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
 TMTC3
 transmembrane and tetratricopeptide repeat containing 3
chr1_-_41131326 0.39 ENST00000372684.3
 RIMS3
 regulating synaptic membrane exocytosis 3
chr7_+_20370746 0.39 ENST00000222573.4
 ITGB8
 integrin, beta 8
chr1_+_32930647 0.38 ENST00000609129.1
 ZBTB8B
 zinc finger and BTB domain containing 8B
chr9_+_101867359 0.38 ENST00000374994.4
 TGFBR1
 transforming growth factor, beta receptor 1
chr22_+_29469012 0.38 ENST00000400335.4
ENST00000400338.2
 KREMEN1
 kringle containing transmembrane protein 1
chr6_+_71122974 0.38 ENST00000418814.2
 FAM135A
 family with sequence similarity 135, member A
chr1_-_225615599 0.38 ENST00000421383.1
ENST00000272163.4
 LBR
 lamin B receptor
chr15_+_39873268 0.37 ENST00000397591.2
ENST00000260356.5
 THBS1
 thrombospondin 1
chr5_+_149109825 0.37 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
 PPARGC1B
 peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr19_+_34287751 0.37 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
 KCTD15
 potassium channel tetramerization domain containing 15
chr16_+_2479390 0.37 ENST00000397066.4
 CCNF
 cyclin F
chr8_-_127570603 0.36 ENST00000304916.3
 FAM84B
 family with sequence similarity 84, member B
chr6_+_117198400 0.36 ENST00000332958.2
 RFX6
 regulatory factor X, 6
chr9_-_126030817 0.36 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
 STRBP
 spermatid perinuclear RNA binding protein
chr9_-_74383799 0.36 ENST00000377044.4
 TMEM2
 transmembrane protein 2
chrX_-_33146477 0.36 ENST00000378677.2
 DMD
 dystrophin
chr5_-_37371278 0.36 ENST00000231498.3
 NUP155
 nucleoporin 155kDa
chr12_+_110719032 0.36 ENST00000395494.2
 ATP2A2
 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chrX_+_49687216 0.35 ENST00000376088.3
 CLCN5
 chloride channel, voltage-sensitive 5
chr8_+_98656336 0.35 ENST00000336273.3
 MTDH
 metadherin
chr9_-_34376851 0.34 ENST00000297625.7
 KIAA1161
 KIAA1161
chr12_-_95611149 0.34 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr7_-_138720763 0.34 ENST00000275766.1
 ZC3HAV1L
 zinc finger CCCH-type, antiviral 1-like
chr12_-_93323013 0.34 ENST00000322349.8
 EEA1
 early endosome antigen 1
chr18_+_55711575 0.33 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr7_-_92463210 0.33 ENST00000265734.4
 CDK6
 cyclin-dependent kinase 6
chr19_+_51815102 0.33 ENST00000270642.8
 IGLON5
 IgLON family member 5
chr2_+_153574428 0.31 ENST00000326446.5
 ARL6IP6
 ADP-ribosylation-like factor 6 interacting protein 6
chr11_+_20620946 0.31 ENST00000525748.1
 SLC6A5
 solute carrier family 6 (neurotransmitter transporter), member 5
chr22_+_50624323 0.31 ENST00000380909.4
ENST00000303434.4
 TRABD
 TraB domain containing
chr12_-_102224704 0.31 ENST00000299314.7
 GNPTAB
 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr10_-_103874692 0.31 ENST00000361198.5
 LDB1
 LIM domain binding 1
chr7_+_76090993 0.31 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
 DTX2
 deltex homolog 2 (Drosophila)
chr1_-_211752073 0.30 ENST00000367001.4
 SLC30A1
 solute carrier family 30 (zinc transporter), member 1
chr22_+_25960786 0.30 ENST00000324198.6
 ADRBK2
 adrenergic, beta, receptor kinase 2
chr2_+_99953816 0.30 ENST00000289371.6
 EIF5B
 eukaryotic translation initiation factor 5B
chrX_-_24690771 0.30 ENST00000379145.1
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chrX_+_118370211 0.30 ENST00000217971.7
 PGRMC1
 progesterone receptor membrane component 1
chr12_+_49372251 0.29 ENST00000293549.3
 WNT1
 wingless-type MMTV integration site family, member 1
chr15_+_90544532 0.29 ENST00000268154.4
 ZNF710
 zinc finger protein 710
chr3_-_52090461 0.29 ENST00000296483.6
ENST00000495880.1
 DUSP7
 dual specificity phosphatase 7
chr1_-_247094628 0.29 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
 AHCTF1
 AT hook containing transcription factor 1
chr17_-_38721711 0.29 ENST00000578085.1
ENST00000246657.2
 CCR7
 chemokine (C-C motif) receptor 7
chr19_+_6531010 0.29 ENST00000245817.3
 TNFSF9
 tumor necrosis factor (ligand) superfamily, member 9
chrX_+_21857717 0.29 ENST00000379484.5
 MBTPS2
 membrane-bound transcription factor peptidase, site 2
chr13_+_52158610 0.29 ENST00000298125.5
 WDFY2
 WD repeat and FYVE domain containing 2
chr9_+_4662282 0.29 ENST00000381883.2
 PPAPDC2
 phosphatidic acid phosphatase type 2 domain containing 2
chr16_+_81348528 0.29 ENST00000568107.2
 GAN
 gigaxonin
chr12_-_89919965 0.28 ENST00000548729.1
 POC1B-GALNT4
 POC1B-GALNT4 readthrough
chr20_+_49348081 0.28 ENST00000371610.2
 PARD6B
 par-6 family cell polarity regulator beta
chr8_-_104427313 0.28 ENST00000297578.4
 SLC25A32
 solute carrier family 25 (mitochondrial folate carrier), member 32
chr17_-_77005801 0.28 ENST00000392446.5
 CANT1
 calcium activated nucleotidase 1
chr2_+_74881355 0.28 ENST00000357877.2
 SEMA4F
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr9_-_111696340 0.27 ENST00000374647.5
 IKBKAP
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr15_-_23086394 0.27 ENST00000337435.4
 NIPA1
 non imprinted in Prader-Willi/Angelman syndrome 1
chr2_+_232260254 0.27 ENST00000287590.5
 B3GNT7
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr1_-_212004090 0.27 ENST00000366997.4
 LPGAT1
 lysophosphatidylglycerol acyltransferase 1
chr5_+_56111361 0.27 ENST00000399503.3
 MAP3K1
 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr16_-_2246436 0.27 ENST00000343516.6
 CASKIN1
 CASK interacting protein 1
chr2_+_219575543 0.27 ENST00000457313.1
ENST00000415717.1
ENST00000392102.1
 TTLL4
 tubulin tyrosine ligase-like family, member 4
chr10_+_73724123 0.26 ENST00000373115.4
 CHST3
 carbohydrate (chondroitin 6) sulfotransferase 3
chr18_+_21032781 0.26 ENST00000339486.3
 RIOK3
 RIO kinase 3
chr1_-_55680762 0.26 ENST00000407756.1
ENST00000294383.6
 USP24
 ubiquitin specific peptidase 24
chrX_+_105066524 0.26 ENST00000243300.9
ENST00000428173.2
 NRK
 Nik related kinase
chr2_-_230933709 0.26 ENST00000436869.1
ENST00000295190.4
 SLC16A14
 solute carrier family 16, member 14
chr8_-_144623595 0.26 ENST00000262577.5
 ZC3H3
 zinc finger CCCH-type containing 3
chr12_-_89918522 0.25 ENST00000529983.2
 GALNT4
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr5_-_159739532 0.25 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
 CCNJL
 cyclin J-like
chr5_+_72861560 0.25 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
 UTP15
 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr2_+_128848881 0.25 ENST00000259253.6
 UGGT1
 UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_10262442 0.25 ENST00000360566.2
 RRM2
 ribonucleotide reductase M2
chr17_+_3539744 0.25 ENST00000046640.3
ENST00000381870.3
 CTNS
 cystinosin, lysosomal cystine transporter
chr1_-_157108130 0.25 ENST00000368192.4
 ETV3
 ets variant 3
chr1_-_184723942 0.24 ENST00000318130.8
 EDEM3
 ER degradation enhancer, mannosidase alpha-like 3
chr3_-_33686743 0.24 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr1_-_93645818 0.24 ENST00000370280.1
ENST00000479918.1
 TMED5
 transmembrane emp24 protein transport domain containing 5
chr8_+_41435696 0.24 ENST00000396987.3
ENST00000519853.1
 AGPAT6
 1-acylglycerol-3-phosphate O-acyltransferase 6
chr20_-_50419055 0.24 ENST00000217086.4
 SALL4
 spalt-like transcription factor 4
chrX_+_147582130 0.24 ENST00000370460.2
ENST00000370457.5
 AFF2
 AF4/FMR2 family, member 2
chr16_+_70148230 0.24 ENST00000398122.3
ENST00000568530.1
 PDPR
 pyruvate dehydrogenase phosphatase regulatory subunit
chr1_+_203595903 0.23 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
chr16_+_22217577 0.23 ENST00000263026.5
 EEF2K
 eukaryotic elongation factor-2 kinase
chr6_+_11094266 0.23 ENST00000416247.2
 SMIM13
 small integral membrane protein 13
chr19_+_47249302 0.23 ENST00000601299.1
ENST00000318584.5
ENST00000595570.1
ENST00000598271.1
ENST00000597313.1
ENST00000593875.1
ENST00000391909.3
ENST00000602250.1
ENST00000595868.1
ENST00000600629.1
ENST00000602181.1
ENST00000593800.1
ENST00000600227.1
ENST00000600005.1
ENST00000594467.1
ENST00000596460.1
 FKRP
 fukutin related protein
chr3_-_171178157 0.23 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
 TNIK
 TRAF2 and NCK interacting kinase
chr22_+_21771656 0.23 ENST00000407464.2
 HIC2
 hypermethylated in cancer 2
chr5_+_38846101 0.23 ENST00000274276.3
 OSMR
 oncostatin M receptor
chr3_-_183735731 0.23 ENST00000334444.6
 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_-_53080047 0.23 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
 SFMBT1
 Scm-like with four mbt domains 1
chr15_+_40861487 0.22 ENST00000315616.7
ENST00000559271.1
 RPUSD2
 RNA pseudouridylate synthase domain containing 2
chr2_-_158485387 0.22 ENST00000243349.8
 ACVR1C
 activin A receptor, type IC
chr21_-_42880075 0.22 ENST00000332149.5
 TMPRSS2
 transmembrane protease, serine 2
chrX_+_56259316 0.22 ENST00000468660.1
 KLF8
 Kruppel-like factor 8
chr19_+_4007644 0.22 ENST00000262971.2
 PIAS4
 protein inhibitor of activated STAT, 4
chr6_-_86352642 0.22 ENST00000355238.6
 SYNCRIP
 synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_+_184097836 0.21 ENST00000204604.1
ENST00000310236.3
 CHRD
 chordin
chr12_+_53662073 0.21 ENST00000553219.1
ENST00000257934.4
 ESPL1
 extra spindle pole bodies homolog 1 (S. cerevisiae)
chr17_+_18218587 0.21 ENST00000406438.3
 SMCR8
 Smith-Magenis syndrome chromosome region, candidate 8
chr2_+_204801471 0.21 ENST00000316386.6
ENST00000435193.1
 ICOS
 inducible T-cell co-stimulator
chr19_+_38810447 0.21 ENST00000263372.3
 KCNK6
 potassium channel, subfamily K, member 6
chr3_-_121553830 0.21 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
 IQCB1
 IQ motif containing B1
chr1_+_15736359 0.21 ENST00000375980.4
 EFHD2
 EF-hand domain family, member D2
chr10_+_102106829 0.20 ENST00000370355.2
 SCD
 stearoyl-CoA desaturase (delta-9-desaturase)
chr21_+_42539701 0.20 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
 BACE2
 beta-site APP-cleaving enzyme 2
chr12_+_1800179 0.20 ENST00000357103.4
 ADIPOR2
 adiponectin receptor 2
chr11_+_59522532 0.20 ENST00000337979.4
ENST00000535361.1
 STX3
 syntaxin 3
chr11_-_27494279 0.20 ENST00000379214.4
 LGR4
 leucine-rich repeat containing G protein-coupled receptor 4
chr1_-_179198702 0.20 ENST00000502732.1
 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
chr6_+_43395272 0.20 ENST00000372530.4
 ABCC10
 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr1_+_101361626 0.20 ENST00000370112.4
 SLC30A7
 solute carrier family 30 (zinc transporter), member 7
chr11_-_86666427 0.20 ENST00000531380.1
 FZD4
 frizzled family receptor 4
chr1_-_24126892 0.20 ENST00000374497.3
ENST00000425913.1
 GALE
 UDP-galactose-4-epimerase
chr4_+_88571429 0.19 ENST00000339673.6
ENST00000282479.7
 DMP1
 dentin matrix acidic phosphoprotein 1
chr13_+_110959598 0.19 ENST00000360467.5
 COL4A2
 collagen, type IV, alpha 2
chr11_+_86748863 0.19 ENST00000340353.7
 TMEM135
 transmembrane protein 135
chr10_+_72238517 0.19 ENST00000263563.6
 PALD1
 phosphatase domain containing, paladin 1
chr8_-_67579418 0.19 ENST00000310421.4
 VCPIP1
 valosin containing protein (p97)/p47 complex interacting protein 1
chr17_-_46608272 0.19 ENST00000577092.1
ENST00000239174.6
 HOXB1
 homeobox B1
chr2_-_39664405 0.19 ENST00000341681.5
ENST00000263881.3
 MAP4K3
 mitogen-activated protein kinase kinase kinase kinase 3
chr11_-_118023490 0.18 ENST00000324727.4
 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
chrX_+_134654540 0.18 ENST00000370752.4
 DDX26B
 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr2_+_191045562 0.18 ENST00000340623.4
 C2orf88
 chromosome 2 open reading frame 88
chr2_+_177053307 0.18 ENST00000331462.4
 HOXD1
 homeobox D1
chr17_-_42908155 0.18 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
 GJC1
 gap junction protein, gamma 1, 45kDa
chr1_-_179846928 0.18 ENST00000367612.3
ENST00000609928.1
 TOR1AIP2
 torsin A interacting protein 2
chr4_+_128554081 0.18 ENST00000335251.6
ENST00000296461.5
 INTU
 inturned planar cell polarity protein
chr2_+_119981384 0.18 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
 STEAP3
 STEAP family member 3, metalloreductase
chr19_+_14063278 0.18 ENST00000254337.6
 DCAF15
 DDB1 and CUL4 associated factor 15
chr15_+_98503922 0.18 ENST00000268042.6
 ARRDC4
 arrestin domain containing 4
chr2_+_168725458 0.18 ENST00000392690.3
 B3GALT1
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.3 0.8 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.3 0.8 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 0.8 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 0.7 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.2 0.7 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.2 0.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.7 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.2 0.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 0.7 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 0.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 0.4 GO:0061346 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 1.7 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.1 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.4 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.4 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.6 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.9 GO:0015820 leucine transport(GO:0015820)
0.1 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.4 GO:0003343 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.5 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.3 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.7 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.2 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.5 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.2 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.4 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.1 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.1 GO:1903061 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) positive regulation of protein lipidation(GO:1903061) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.6 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.0 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.2 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 0.5 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.3 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.3 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0043583 ear development(GO:0043583)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.1 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.8 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.0 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0051534 regulation of NFAT protein import into nucleus(GO:0051532) negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.0 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048) midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.1 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 1.0 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.7 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 0.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.8 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.8 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.3 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.8 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling