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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GATA1_GATA4

Z-value: 1.52

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
GATA1
ENSG00000102145.9 GATA1
GATA4
ENSG00000136574.13 GATA4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA1hg19_v2_chrX_+_48644962_486449830.648.9e-02Click!
GATA4hg19_v2_chr8_+_11534462_115344750.531.8e-01Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_19749386 3.10 ENST00000269216.3
 GATA6
 GATA binding protein 6
chr19_-_51522955 2.58 ENST00000358789.3
 KLK10
 kallikrein-related peptidase 10
chr1_-_201368707 2.35 ENST00000391967.2
 LAD1
 ladinin 1
chr1_-_201368653 2.33 ENST00000367313.3
 LAD1
 ladinin 1
chr8_+_124194875 2.17 ENST00000522648.1
ENST00000276699.6
 FAM83A
 family with sequence similarity 83, member A
chr8_+_124194752 2.04 ENST00000318462.6
 FAM83A
 family with sequence similarity 83, member A
chr10_-_129691195 1.83 ENST00000368671.3
 CLRN3
 clarin 3
chr2_-_165424973 1.81 ENST00000543549.1
 GRB14
 growth factor receptor-bound protein 14
chr12_+_4385230 1.80 ENST00000536537.1
 CCND2
 cyclin D2
chr1_+_209602156 1.74 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
 MIR205HG
 MIR205 host gene (non-protein coding)
chr1_-_24469602 1.70 ENST00000270800.1
 IL22RA1
 interleukin 22 receptor, alpha 1
chr19_-_51523275 1.64 ENST00000309958.3
 KLK10
 kallikrein-related peptidase 10
chr12_-_52845910 1.51 ENST00000252252.3
 KRT6B
 keratin 6B
chr19_+_35739897 1.45 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
 LSR
 lipolysis stimulated lipoprotein receptor
chr1_-_175162048 1.43 ENST00000444639.1
 KIAA0040
 KIAA0040
chr19_+_35739782 1.39 ENST00000347609.4
 LSR
 lipolysis stimulated lipoprotein receptor
chr1_+_35247859 1.28 ENST00000373362.3
 GJB3
 gap junction protein, beta 3, 31kDa
chrX_-_78622805 1.25 ENST00000373298.2
 ITM2A
 integral membrane protein 2A
chr22_-_20231207 1.22 ENST00000425986.1
 RTN4R
 reticulon 4 receptor
chr8_-_15095832 1.17 ENST00000382080.1
 SGCZ
 sarcoglycan, zeta
chr18_+_21452804 1.16 ENST00000269217.6
 LAMA3
 laminin, alpha 3
chr6_+_125540951 1.12 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chr3_+_148583043 1.07 ENST00000296046.3
 CPA3
 carboxypeptidase A3 (mast cell)
chr4_-_103266355 1.05 ENST00000424970.2
 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
chr6_+_1080164 1.05 ENST00000314040.1
 AL033381.1
 Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr1_-_209825674 1.01 ENST00000367030.3
ENST00000356082.4
 LAMB3
 laminin, beta 3
chrX_-_117119243 0.99 ENST00000539496.1
ENST00000469946.1
 KLHL13
 kelch-like family member 13
chr6_-_11779014 0.99 ENST00000229583.5
 ADTRP
 androgen-dependent TFPI-regulating protein
chr5_+_131409476 0.95 ENST00000296871.2
 CSF2
 colony stimulating factor 2 (granulocyte-macrophage)
chr6_-_11779174 0.92 ENST00000379413.2
 ADTRP
 androgen-dependent TFPI-regulating protein
chr19_-_51487071 0.88 ENST00000391807.1
ENST00000593904.1
 KLK7
 kallikrein-related peptidase 7
chr1_+_15256230 0.83 ENST00000376028.4
ENST00000400798.2
 KAZN
 kazrin, periplakin interacting protein
chr6_+_12290586 0.81 ENST00000379375.5
 EDN1
 endothelin 1
chr3_-_194188956 0.81 ENST00000256031.4
ENST00000446356.1
 ATP13A3
 ATPase type 13A3
chr1_+_81771806 0.81 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr9_+_132099158 0.80 ENST00000444125.1
 RP11-65J3.1
 RP11-65J3.1
chr11_-_125648690 0.79 ENST00000436890.2
ENST00000358524.3
 PATE2
 prostate and testis expressed 2
chr3_+_189507432 0.79 ENST00000354600.5
 TP63
 tumor protein p63
chr18_+_61445007 0.79 ENST00000447428.1
ENST00000546027.1
 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_-_24690771 0.78 ENST00000379145.1
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr1_+_202172848 0.78 ENST00000255432.7
 LGR6
 leucine-rich repeat containing G protein-coupled receptor 6
chr6_-_11779403 0.76 ENST00000414691.3
 ADTRP
 androgen-dependent TFPI-regulating protein
chr8_-_20040601 0.75 ENST00000265808.7
ENST00000522513.1
 SLC18A1
 solute carrier family 18 (vesicular monoamine transporter), member 1
chr11_+_128563652 0.75 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr5_+_36608422 0.74 ENST00000381918.3
 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_30614779 0.72 ENST00000293604.6
ENST00000376473.5
 C6orf136
 chromosome 6 open reading frame 136
chr6_-_107235287 0.72 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
 RP1-60O19.1
 RP1-60O19.1
chr3_+_36421826 0.71 ENST00000273183.3
 STAC
 SH3 and cysteine rich domain
chr11_-_116708302 0.71 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
 APOA1
 apolipoprotein A-I
chr2_-_69098566 0.69 ENST00000295379.1
 BMP10
 bone morphogenetic protein 10
chr11_+_34642656 0.68 ENST00000257831.3
ENST00000450654.2
 EHF
 ets homologous factor
chr8_+_32579341 0.68 ENST00000519240.1
ENST00000539990.1
 NRG1
 neuregulin 1
chr8_-_20040638 0.67 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
 SLC18A1
 solute carrier family 18 (vesicular monoamine transporter), member 1
chr1_-_226187013 0.67 ENST00000272091.7
 SDE2
 SDE2 telomere maintenance homolog (S. pombe)
chr17_-_47841485 0.65 ENST00000506156.1
ENST00000240364.2
 FAM117A
 family with sequence similarity 117, member A
chr7_-_20256965 0.63 ENST00000400331.5
ENST00000332878.4
 MACC1
 metastasis associated in colon cancer 1
chrX_-_24665208 0.63 ENST00000356768.4
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr2_+_197504278 0.63 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
 CCDC150
 coiled-coil domain containing 150
chr17_-_39280419 0.63 ENST00000394014.1
 KRTAP4-12
 keratin associated protein 4-12
chr19_-_51487282 0.61 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
 KLK7
 kallikrein-related peptidase 7
chr17_+_74381343 0.61 ENST00000392496.3
 SPHK1
 sphingosine kinase 1
chr6_+_30614886 0.61 ENST00000376471.4
 C6orf136
 chromosome 6 open reading frame 136
chr17_-_41050716 0.60 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
 LINC00671
 long intergenic non-protein coding RNA 671
chr1_-_153113927 0.59 ENST00000368752.4
 SPRR2B
 small proline-rich protein 2B
chr15_-_79237433 0.59 ENST00000220166.5
 CTSH
 cathepsin H
chr14_-_81893734 0.58 ENST00000555447.1
 STON2
 stonin 2
chr15_+_41136216 0.57 ENST00000562057.1
ENST00000344051.4
 SPINT1
 serine peptidase inhibitor, Kunitz type 1
chrX_+_107288239 0.56 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr15_-_52030293 0.55 ENST00000560491.1
ENST00000267838.3
 LYSMD2
 LysM, putative peptidoglycan-binding, domain containing 2
chrX_-_24665353 0.55 ENST00000379144.2
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr4_-_103266219 0.55 ENST00000394833.2
 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
chr1_-_94050668 0.55 ENST00000539242.1
 BCAR3
 breast cancer anti-estrogen resistance 3
chr12_+_9144626 0.54 ENST00000543895.1
 KLRG1
 killer cell lectin-like receptor subfamily G, member 1
chr4_-_72649763 0.52 ENST00000513476.1
 GC
 group-specific component (vitamin D binding protein)
chr19_-_33360647 0.52 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
 SLC7A9
 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr12_+_9102632 0.51 ENST00000539240.1
 KLRG1
 killer cell lectin-like receptor subfamily G, member 1
chr9_-_117692697 0.50 ENST00000223795.2
 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
chr1_+_154293584 0.50 ENST00000324978.3
ENST00000484864.1
 AQP10
 aquaporin 10
chr9_-_124989804 0.50 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr14_-_21566731 0.49 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr3_-_155394099 0.49 ENST00000414191.1
 PLCH1
 phospholipase C, eta 1
chr17_-_34079897 0.49 ENST00000254466.6
ENST00000587565.1
 GAS2L2
 growth arrest-specific 2 like 2
chr11_+_76571911 0.49 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
 ACER3
 alkaline ceramidase 3
chr1_+_87595542 0.48 ENST00000461990.1
 RP5-1052I5.1
 long intergenic non-protein coding RNA 1140
chr3_-_98312548 0.46 ENST00000264193.2
 CPOX
 coproporphyrinogen oxidase
chr9_+_90341024 0.46 ENST00000340342.6
ENST00000342020.5
 CTSL
 cathepsin L
chr12_-_71031220 0.46 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr12_-_71148357 0.45 ENST00000378778.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr1_-_116383322 0.45 ENST00000429731.1
 NHLH2
 nescient helix loop helix 2
chr10_-_96122682 0.45 ENST00000371361.3
 NOC3L
 nucleolar complex associated 3 homolog (S. cerevisiae)
chr20_+_43935474 0.45 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
 RBPJL
 recombination signal binding protein for immunoglobulin kappa J region-like
chr2_+_106361333 0.45 ENST00000233154.4
ENST00000451463.2
 NCK2
 NCK adaptor protein 2
chr12_-_71031185 0.44 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr12_-_71148413 0.43 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr14_+_22966642 0.43 ENST00000390496.1
 TRAJ41
 T cell receptor alpha joining 41
chr8_-_38008783 0.42 ENST00000276449.4
 STAR
 steroidogenic acute regulatory protein
chr22_-_29784519 0.42 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
 AP1B1
 adaptor-related protein complex 1, beta 1 subunit
chr6_-_47010061 0.42 ENST00000371253.2
 GPR110
 G protein-coupled receptor 110
chr11_-_124311054 0.42 ENST00000328064.2
 OR8B8
 olfactory receptor, family 8, subfamily B, member 8
chr6_+_130339710 0.42 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr6_-_170599561 0.42 ENST00000366756.3
 DLL1
 delta-like 1 (Drosophila)
chr4_+_154387480 0.40 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
 KIAA0922
 KIAA0922
chr6_+_29407083 0.40 ENST00000444197.2
 OR10C1
 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr11_+_18154059 0.40 ENST00000531264.1
 MRGPRX3
 MAS-related GPR, member X3
chr3_+_189507523 0.40 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
 TP63
 tumor protein p63
chrX_+_38420623 0.39 ENST00000378482.2
 TSPAN7
 tetraspanin 7
chr1_+_25598989 0.39 ENST00000454452.2
 RHD
 Rh blood group, D antigen
chr14_+_21510385 0.39 ENST00000298690.4
 RNASE7
 ribonuclease, RNase A family, 7
chr6_+_47666275 0.39 ENST00000327753.3
ENST00000283303.2
 GPR115
 G protein-coupled receptor 115
chr19_-_12997995 0.38 ENST00000264834.4
 KLF1
 Kruppel-like factor 1 (erythroid)
chr8_+_104831472 0.38 ENST00000262231.10
ENST00000507740.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chrX_+_107288197 0.38 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr19_+_10397648 0.37 ENST00000340992.4
ENST00000393717.2
 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_+_10397621 0.36 ENST00000380770.3
 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr6_+_29274403 0.36 ENST00000377160.2
 OR14J1
 olfactory receptor, family 14, subfamily J, member 1
chr3_+_112930306 0.36 ENST00000495514.1
 BOC
 BOC cell adhesion associated, oncogene regulated
chr1_-_153029980 0.36 ENST00000392653.2
 SPRR2A
 small proline-rich protein 2A
chr4_+_78432907 0.36 ENST00000286758.4
 CXCL13
 chemokine (C-X-C motif) ligand 13
chr16_+_71560154 0.36 ENST00000539698.3
 CHST4
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr15_-_52587945 0.36 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
 MYO5C
 myosin VC
chr11_+_121461097 0.35 ENST00000527934.1
 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
chr6_+_14117872 0.35 ENST00000379153.3
 CD83
 CD83 molecule
chr16_+_4838412 0.35 ENST00000589327.1
 SMIM22
 small integral membrane protein 22
chr11_-_119993734 0.35 ENST00000533302.1
 TRIM29
 tripartite motif containing 29
chr8_-_91095099 0.35 ENST00000265431.3
 CALB1
 calbindin 1, 28kDa
chr16_+_4838393 0.35 ENST00000589721.1
 SMIM22
 small integral membrane protein 22
chr18_+_55888767 0.35 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_-_119993979 0.35 ENST00000524816.3
ENST00000525327.1
 TRIM29
 tripartite motif containing 29
chr1_-_235098935 0.35 ENST00000423175.1
 RP11-443B7.1
 RP11-443B7.1
chr11_-_59612969 0.34 ENST00000541311.1
ENST00000257248.2
 GIF
 gastric intrinsic factor (vitamin B synthesis)
chr13_-_31736478 0.34 ENST00000445273.2
 HSPH1
 heat shock 105kDa/110kDa protein 1
chr16_+_71560023 0.34 ENST00000572450.1
 CHST4
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr2_+_189156638 0.34 ENST00000410051.1
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr13_-_46716969 0.34 ENST00000435666.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_139528952 0.34 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
 TBXAS1
 thromboxane A synthase 1 (platelet)
chr7_+_39125365 0.33 ENST00000559001.1
ENST00000464276.2
 POU6F2
 POU class 6 homeobox 2
chr9_+_139557360 0.33 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
 EGFL7
 EGF-like-domain, multiple 7
chr5_-_172036436 0.32 ENST00000601856.1
 AC027309.1
 AC027309.1
chrX_+_128913906 0.32 ENST00000356892.3
 SASH3
 SAM and SH3 domain containing 3
chr15_-_34610962 0.32 ENST00000290209.5
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr12_+_29376673 0.32 ENST00000547116.1
 FAR2
 fatty acyl CoA reductase 2
chr6_-_52628271 0.32 ENST00000493422.1
 GSTA2
 glutathione S-transferase alpha 2
chr8_-_95449155 0.32 ENST00000481490.2
 FSBP
 fibrinogen silencer binding protein
chr9_+_273038 0.32 ENST00000487230.1
ENST00000469391.1
 DOCK8
 dedicator of cytokinesis 8
chr12_+_29376592 0.32 ENST00000182377.4
 FAR2
 fatty acyl CoA reductase 2
chr1_-_225616515 0.32 ENST00000338179.2
ENST00000425080.1
 LBR
 lamin B receptor
chr3_-_119379427 0.32 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
 POPDC2
 popeye domain containing 2
chr1_-_153013588 0.31 ENST00000360379.3
 SPRR2D
 small proline-rich protein 2D
chr1_-_54872059 0.31 ENST00000371320.3
 SSBP3
 single stranded DNA binding protein 3
chr11_+_128563948 0.31 ENST00000534087.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr15_+_77287426 0.31 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
 PSTPIP1
 proline-serine-threonine phosphatase interacting protein 1
chr17_-_73840415 0.31 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
 UNC13D
 unc-13 homolog D (C. elegans)
chr15_-_34628951 0.31 ENST00000397707.2
ENST00000560611.1
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr17_-_27418537 0.30 ENST00000408971.2
 TIAF1
 TGFB1-induced anti-apoptotic factor 1
chr7_+_150549565 0.30 ENST00000360937.4
ENST00000416793.2
ENST00000483043.1
 AOC1
 amine oxidase, copper containing 1
chr12_+_53662110 0.30 ENST00000552462.1
 ESPL1
 extra spindle pole bodies homolog 1 (S. cerevisiae)
chr2_+_174219548 0.30 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
 CDCA7
 cell division cycle associated 7
chr17_-_38938786 0.30 ENST00000301656.3
 KRT27
 keratin 27
chr1_+_31883048 0.29 ENST00000536859.1
 SERINC2
 serine incorporator 2
chr4_-_143227088 0.29 ENST00000511838.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_+_38211777 0.29 ENST00000039007.4
 OTC
 ornithine carbamoyltransferase
chrX_-_84634737 0.29 ENST00000262753.4
 POF1B
 premature ovarian failure, 1B
chr1_+_174846570 0.29 ENST00000392064.2
 RABGAP1L
 RAB GTPase activating protein 1-like
chr8_+_99956759 0.29 ENST00000522510.1
ENST00000457907.2
 OSR2
 odd-skipped related transciption factor 2
chr10_+_5566916 0.29 ENST00000315238.1
 CALML3
 calmodulin-like 3
chr10_+_90424196 0.29 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
 LIPF
 lipase, gastric
chr15_-_43513187 0.29 ENST00000540029.1
ENST00000441366.2
 EPB42
 erythrocyte membrane protein band 4.2
chr12_-_120765565 0.29 ENST00000423423.3
ENST00000308366.4
 PLA2G1B
 phospholipase A2, group IB (pancreas)
chr10_-_99531709 0.29 ENST00000266066.3
 SFRP5
 secreted frizzled-related protein 5
chr15_+_78632666 0.29 ENST00000299529.6
 CRABP1
 cellular retinoic acid binding protein 1
chr8_-_86290333 0.28 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
 CA1
 carbonic anhydrase I
chr1_-_116383738 0.28 ENST00000320238.3
 NHLH2
 nescient helix loop helix 2
chr7_-_95951334 0.28 ENST00000265631.5
 SLC25A13
 solute carrier family 25 (aspartate/glutamate carrier), member 13
chr1_-_153521714 0.28 ENST00000368713.3
 S100A3
 S100 calcium binding protein A3
chr7_-_138666053 0.28 ENST00000440172.1
ENST00000422774.1
 KIAA1549
 KIAA1549
chr21_-_34915147 0.28 ENST00000381831.3
ENST00000381839.3
 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr2_-_8464760 0.28 ENST00000430192.1
 LINC00299
 long intergenic non-protein coding RNA 299
chr17_-_64225508 0.28 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr20_+_51588873 0.28 ENST00000371497.5
 TSHZ2
 teashirt zinc finger homeobox 2
chr11_-_1036706 0.27 ENST00000421673.2
 MUC6
 mucin 6, oligomeric mucus/gel-forming
chr4_-_143226979 0.27 ENST00000514525.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_-_79816965 0.27 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr11_+_129720227 0.27 ENST00000524567.1
 TMEM45B
 transmembrane protein 45B
chr13_-_46756351 0.27 ENST00000323076.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_17480779 0.27 ENST00000395782.1
 PEMT
 phosphatidylethanolamine N-methyltransferase
chr6_+_31674639 0.27 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
 LY6G6F
MEGT1
 lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr1_-_153521597 0.27 ENST00000368712.1
 S100A3
 S100 calcium binding protein A3
chr7_-_16505440 0.27 ENST00000307068.4
 SOSTDC1
 sclerostin domain containing 1
chr17_-_54893250 0.26 ENST00000397862.2
 C17orf67
 chromosome 17 open reading frame 67
chr1_-_177134024 0.26 ENST00000367654.3
 ASTN1
 astrotactin 1
chr2_+_189156389 0.26 ENST00000409843.1
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr1_+_199996733 0.26 ENST00000236914.3
 NR5A2
 nuclear receptor subfamily 5, group A, member 2
chr10_+_32873190 0.26 ENST00000375025.4
 C10orf68
 Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr14_-_72458326 0.26 ENST00000542853.1
 AC005477.1
 AC005477.1
chrX_-_63450480 0.26 ENST00000362002.2
 ASB12
 ankyrin repeat and SOCS box containing 12
chr2_+_32390925 0.26 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
 SLC30A6
 solute carrier family 30 (zinc transporter), member 6
chr1_-_225615599 0.25 ENST00000421383.1
ENST00000272163.4
 LBR
 lamin B receptor
chr6_-_9939552 0.24 ENST00000460363.2
 OFCC1
 orofacial cleft 1 candidate 1
chr7_-_99381798 0.24 ENST00000415003.1
ENST00000354593.2
 CYP3A4
 cytochrome P450, family 3, subfamily A, polypeptide 4
chr2_+_102927962 0.24 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
 IL1RL1
IL18R1
 interleukin 1 receptor-like 1
interleukin 18 receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.6 2.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.3 1.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 0.8 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 1.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 1.5 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 1.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 0.2 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.7 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.2 2.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.8 GO:1990523 bone regeneration(GO:1990523)
0.1 0.6 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 1.6 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.4 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.5 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.4 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.6 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.7 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.1 0.3 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 1.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 0.4 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 1.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.6 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.1 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.3 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.3 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.3 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.6 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.1 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:2000182 positive regulation of mitochondrial DNA metabolic process(GO:1901860) regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.5 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 1.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0071611 granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.4 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.7 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.6 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.0 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 1.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 3.6 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.6 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0061689 tricellular tight junction(GO:0061689)
0.3 1.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 2.2 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 4.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.1 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 1.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.4 2.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 3.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.7 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 0.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.6 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 3.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.8 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.6 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 1.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 2.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 5.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0016918 retinal binding(GO:0016918)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation