Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
GATA2 Links Ensembl NCBI GeneCards UniProt	ENSG00000179348.7	GATA2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GATA2	hg19_v2_chr3_-_128206759_128206781	-0.64	8.9e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr12_-_91546926	3.67	ENST00000550758.1	DCN	decorin
chr12_-_91573132	2.96	ENST00000550563.1 ENST00000546370.1	DCN	decorin
chr1_+_78956651	2.44	ENST00000370757.3 ENST00000370756.3	PTGFR	prostaglandin F receptor (FP)
chr13_+_102142296	2.38	ENST00000376162.3	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr2_-_202562774	1.96	ENST00000396886.3 ENST00000409143.1	MPP4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_114522049	1.78	ENST00000369551.1 ENST00000320334.4	OLFML3	olfactomedin-like 3
chr5_-_20575959	1.70	ENST00000507958.1	CDH18	cadherin 18, type 2
chr10_+_69865866	1.66	ENST00000354393.2	MYPN	myopalladin
chr20_+_34802295	1.64	ENST00000432603.1	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr12_-_91572278	1.57	ENST00000425043.1 ENST00000420120.2 ENST00000441303.2 ENST00000456569.2	DCN	decorin
chr1_+_183774240	1.55	ENST00000360851.3	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr1_+_180165672	1.34	ENST00000443059.1	QSOX1	quiescin Q6 sulfhydryl oxidase 1
chr2_-_202562716	1.29	ENST00000428900.2	MPP4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr5_-_19988339	1.27	ENST00000382275.1	CDH18	cadherin 18, type 2
chr13_+_76378357	1.25	ENST00000489941.2 ENST00000525373.1	LMO7	LIM domain 7
chr4_-_70626314	1.24	ENST00000510821.1	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr9_-_79307096	1.20	ENST00000376717.2 ENST00000223609.6 ENST00000443509.2	PRUNE2	prune homolog 2 (Drosophila)
chr16_+_55512742	1.20	ENST00000568715.1 ENST00000219070.4	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr7_+_94023873	1.19	ENST00000297268.6	COL1A2	collagen, type I, alpha 2
chr19_+_14551066	1.17	ENST00000342216.4	PKN1	protein kinase N1
chr10_-_79397391	1.14	ENST00000286628.8 ENST00000406533.3 ENST00000354353.5 ENST00000404857.1	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_+_71403061	1.13	ENST00000512974.1 ENST00000296755.7	MAP1B	microtubule-associated protein 1B
chr5_-_75919253	1.13	ENST00000296641.4	F2RL2	coagulation factor II (thrombin) receptor-like 2
chr17_-_48278983	1.03	ENST00000225964.5	COL1A1	collagen, type I, alpha 1
chr5_-_75919217	0.94	ENST00000504899.1	F2RL2	coagulation factor II (thrombin) receptor-like 2
chr2_-_158345462	0.93	ENST00000439355.1 ENST00000540637.1	CYTIP	cytohesin 1 interacting protein
chr2_+_201450591	0.91	ENST00000374700.2	AOX1	aldehyde oxidase 1
chr12_-_47219733	0.91	ENST00000547477.1 ENST00000447411.1 ENST00000266579.4	SLC38A4	solute carrier family 38, member 4
chr10_-_79397316	0.91	ENST00000372421.5 ENST00000457953.1	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_78383813	0.91	ENST00000342754.5	NEXN	nexilin (F actin binding protein)
chr9_+_90112117	0.91	ENST00000358077.5	DAPK1	death-associated protein kinase 1
chr3_+_69812701	0.87	ENST00000472437.1	MITF	microphthalmia-associated transcription factor
chr13_-_33780133	0.87	ENST00000399365.3	STARD13	StAR-related lipid transfer (START) domain containing 13
chr5_+_148521136	0.86	ENST00000506113.1	ABLIM3	actin binding LIM protein family, member 3
chr12_-_91573249	0.85	ENST00000550099.1 ENST00000546391.1 ENST00000551354.1	DCN	decorin
chr5_+_140772381	0.85	ENST00000398604.2	PCDHGA8	protocadherin gamma subfamily A, 8
chr6_-_87804815	0.85	ENST00000369582.2	CGA	glycoprotein hormones, alpha polypeptide
chr10_-_79397479	0.82	ENST00000404771.3	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_+_126237554	0.80	ENST00000394329.3	FAT4	FAT atypical cadherin 4
chr2_-_190044480	0.80	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr9_+_2029019	0.79	ENST00000382194.1	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_32838801	0.77	ENST00000542859.1	FRY	furry homolog (Drosophila)
chrX_+_149531524	0.76	ENST00000370401.2	MAMLD1	mastermind-like domain containing 1
chr10_-_79397202	0.75	ENST00000372437.1 ENST00000372408.2 ENST00000372403.4	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_15528332	0.74	ENST00000566490.1	C16orf45	chromosome 16 open reading frame 45
chr5_-_147286065	0.73	ENST00000318315.4 ENST00000515291.1	C5orf46	chromosome 5 open reading frame 46
chr3_+_141105235	0.72	ENST00000503809.1	ZBTB38	zinc finger and BTB domain containing 38
chr3_-_8811288	0.72	ENST00000316793.3 ENST00000431493.1	OXTR	oxytocin receptor
chr13_+_76378305	0.70	ENST00000526371.1 ENST00000526528.1	LMO7	LIM domain 7
chr4_-_89619386	0.68	ENST00000323061.5	NAP1L5	nucleosome assembly protein 1-like 5
chr5_-_172198190	0.67	ENST00000239223.3	DUSP1	dual specificity phosphatase 1
chr4_-_57547454	0.66	ENST00000556376.2	HOPX	HOP homeobox
chr3_+_141043050	0.65	ENST00000509842.1	ZBTB38	zinc finger and BTB domain containing 38
chr11_-_59633951	0.65	ENST00000257264.3	TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)
chr3_+_154797877	0.64	ENST00000462745.1 ENST00000493237.1	MME	membrane metallo-endopeptidase
chr15_-_93616340	0.63	ENST00000557420.1 ENST00000542321.2	RGMA	repulsive guidance molecule family member a
chr6_-_152639479	0.63	ENST00000356820.4	SYNE1	spectrin repeat containing, nuclear envelope 1
chr20_+_12989596	0.63	ENST00000434210.1 ENST00000399002.2	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chrX_-_77395186	0.61	ENST00000341864.5	TAF9B	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr12_+_75874460	0.60	ENST00000266659.3	GLIPR1	GLI pathogenesis-related 1
chr5_+_148737562	0.60	ENST00000274569.4	PCYOX1L	prenylcysteine oxidase 1 like
chr10_+_64133934	0.60	ENST00000395254.3 ENST00000395255.3 ENST00000410046.3	ZNF365	zinc finger protein 365
chr1_-_232651312	0.60	ENST00000262861.4	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr22_+_42665742	0.60	ENST00000332965.3 ENST00000415205.1 ENST00000446578.1	Z83851.3	Z83851.3
chr8_+_70404996	0.59	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr3_-_149095652	0.59	ENST00000305366.3	TM4SF1	transmembrane 4 L six family member 1
chr1_-_150780757	0.59	ENST00000271651.3	CTSK	cathepsin K
chr4_-_57547870	0.59	ENST00000381260.3 ENST00000420433.1 ENST00000554144.1 ENST00000557328.1	HOPX	HOP homeobox
chr5_-_159797627	0.58	ENST00000393975.3	C1QTNF2	C1q and tumor necrosis factor related protein 2
chr8_-_23712312	0.57	ENST00000290271.2	STC1	stanniocalcin 1
chr6_-_46293378	0.56	ENST00000330430.6	RCAN2	regulator of calcineurin 2
chr2_+_201994569	0.56	ENST00000457277.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr5_+_140753444	0.56	ENST00000517434.1	PCDHGA6	protocadherin gamma subfamily A, 6
chr11_-_96076334	0.56	ENST00000524717.1	MAML2	mastermind-like 2 (Drosophila)
chr1_-_182369751	0.55	ENST00000367565.1	TEDDM1	transmembrane epididymal protein 1
chr7_-_38670957	0.54	ENST00000325590.5 ENST00000428293.2	AMPH	amphiphysin
chr7_-_38671098	0.54	ENST00000356264.2	AMPH	amphiphysin
chr3_-_178969403	0.53	ENST00000314235.5 ENST00000392685.2	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_-_167276033	0.53	ENST00000503859.1 ENST00000506565.1	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_-_207082748	0.53	ENST00000407325.2 ENST00000411719.1	GPR1	G protein-coupled receptor 1
chr12_-_92539614	0.53	ENST00000256015.3	BTG1	B-cell translocation gene 1, anti-proliferative
chr6_-_24936170	0.53	ENST00000538035.1	FAM65B	family with sequence similarity 65, member B
chr7_+_129932974	0.53	ENST00000445470.2 ENST00000222482.4 ENST00000492072.1 ENST00000473956.1 ENST00000493259.1 ENST00000486598.1	CPA4	carboxypeptidase A4
chr1_+_201617264	0.53	ENST00000367296.4	NAV1	neuron navigator 1
chr5_+_67588391	0.52	ENST00000523872.1	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_+_75874580	0.52	ENST00000456650.3	GLIPR1	GLI pathogenesis-related 1
chr2_-_85555385	0.52	ENST00000377386.3	TGOLN2	trans-golgi network protein 2
chr17_-_15165854	0.51	ENST00000395936.1 ENST00000395938.2	PMP22	peripheral myelin protein 22
chr17_-_8702667	0.49	ENST00000329805.4	MFSD6L	major facilitator superfamily domain containing 6-like
chr8_-_93029520	0.49	ENST00000521553.1	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_90085458	0.49	ENST00000345097.4 ENST00000555855.1 ENST00000555353.1	FOXN3	forkhead box N3
chr10_+_45495898	0.48	ENST00000298299.3	ZNF22	zinc finger protein 22
chr5_-_180688105	0.48	ENST00000327767.4	TRIM52	tripartite motif containing 52
chr3_-_49170405	0.48	ENST00000305544.4 ENST00000494831.1	LAMB2	laminin, beta 2 (laminin S)
chr19_-_9003586	0.47	ENST00000380951.5	MUC16	mucin 16, cell surface associated
chr19_+_41509851	0.47	ENST00000593831.1 ENST00000330446.5	CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr8_-_27468945	0.47	ENST00000405140.3	CLU	clusterin
chr3_-_178976996	0.46	ENST00000485523.1	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr7_+_134430212	0.46	ENST00000436461.2	CALD1	caldesmon 1
chr2_-_192711968	0.46	ENST00000304141.4	SDPR	serum deprivation response
chr13_-_114843416	0.45	ENST00000389544.4	RASA3	RAS p21 protein activator 3
chr12_+_60058458	0.45	ENST00000548610.1	SLC16A7	solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_49170522	0.45	ENST00000418109.1	LAMB2	laminin, beta 2 (laminin S)
chr12_-_11002063	0.44	ENST00000544994.1 ENST00000228811.4 ENST00000540107.1	PRR4	proline rich 4 (lacrimal)
chr6_+_72922590	0.44	ENST00000523963.1	RIMS1	regulating synaptic membrane exocytosis 1
chr7_+_134528635	0.44	ENST00000445569.2	CALD1	caldesmon 1
chr12_-_124457257	0.44	ENST00000545891.1	CCDC92	coiled-coil domain containing 92
chr3_-_48594248	0.43	ENST00000545984.1 ENST00000232375.3 ENST00000416568.1 ENST00000383734.2 ENST00000541519.1 ENST00000412035.1	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr5_-_88119580	0.43	ENST00000539796.1	MEF2C	myocyte enhancer factor 2C
chr2_-_175711133	0.43	ENST00000409597.1 ENST00000413882.1	CHN1	chimerin 1
chr2_+_210444142	0.43	ENST00000360351.4 ENST00000361559.4	MAP2	microtubule-associated protein 2
chr11_+_117073850	0.42	ENST00000529622.1	TAGLN	transgelin
chr22_+_21737663	0.42	ENST00000434111.1	RIMBP3B	RIMS binding protein 3B
chr19_+_39786962	0.42	ENST00000333625.2	IFNL1	interferon, lambda 1
chr3_+_148415571	0.42	ENST00000497524.1 ENST00000349243.3 ENST00000542281.1 ENST00000418473.2 ENST00000404754.2	AGTR1	angiotensin II receptor, type 1
chr6_+_72922505	0.42	ENST00000401910.3	RIMS1	regulating synaptic membrane exocytosis 1
chr1_-_84464780	0.42	ENST00000260505.8	TTLL7	tubulin tyrosine ligase-like family, member 7
chr11_+_20044096	0.41	ENST00000533917.1	NAV2	neuron navigator 2
chr17_+_4853442	0.41	ENST00000522301.1	ENO3	enolase 3 (beta, muscle)
chr20_-_39928705	0.41	ENST00000436099.2 ENST00000309060.3 ENST00000373261.1 ENST00000436440.2 ENST00000540170.1 ENST00000557816.1 ENST00000560361.1	ZHX3	zinc fingers and homeoboxes 3
chr11_-_121986923	0.41	ENST00000560104.1	BLID	BH3-like motif containing, cell death inducer
chr13_-_23949671	0.40	ENST00000402364.1	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_-_241799232	0.40	ENST00000366553.1	CHML	choroideremia-like (Rab escort protein 2)
chr3_+_191046810	0.40	ENST00000392455.3 ENST00000392456.3	CCDC50	coiled-coil domain containing 50
chr8_-_27468842	0.39	ENST00000523500.1	CLU	clusterin
chr8_-_131399110	0.39	ENST00000521426.1	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr15_-_63449663	0.39	ENST00000439025.1	RPS27L	ribosomal protein S27-like
chr1_+_161136180	0.39	ENST00000352210.5 ENST00000367999.4 ENST00000544598.1 ENST00000535223.1 ENST00000432542.2	PPOX	protoporphyrinogen oxidase
chr13_+_24144509	0.39	ENST00000248484.4	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr2_+_170683979	0.38	ENST00000418381.1	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr7_-_8302207	0.37	ENST00000407906.1	ICA1	islet cell autoantigen 1, 69kDa
chr3_+_29322437	0.37	ENST00000434693.2	RBMS3	RNA binding motif, single stranded interacting protein 3
chr11_-_8680383	0.37	ENST00000299550.6	TRIM66	tripartite motif containing 66
chr9_-_21305312	0.37	ENST00000259555.4	IFNA5	interferon, alpha 5
chr10_-_15413035	0.37	ENST00000378116.4 ENST00000455654.1	FAM171A1	family with sequence similarity 171, member A1
chr2_-_169769787	0.37	ENST00000451987.1	SPC25	SPC25, NDC80 kinetochore complex component
chr20_-_3996036	0.36	ENST00000336095.6	RNF24	ring finger protein 24
chr14_+_21156915	0.36	ENST00000397990.4 ENST00000555597.1	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr14_-_92198403	0.36	ENST00000553329.1 ENST00000256343.3	CATSPERB	catsper channel auxiliary subunit beta
chr12_-_71533055	0.36	ENST00000552128.1	TSPAN8	tetraspanin 8
chr3_-_197676740	0.36	ENST00000452735.1 ENST00000453254.1 ENST00000455191.1	IQCG	IQ motif containing G
chr9_+_37667978	0.36	ENST00000539465.1	FRMPD1	FERM and PDZ domain containing 1
chr2_+_201994042	0.36	ENST00000417748.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr5_+_173316341	0.35	ENST00000520867.1 ENST00000334035.5	CPEB4	cytoplasmic polyadenylation element binding protein 4
chr11_-_124670550	0.35	ENST00000239614.4	MSANTD2	Myb/SANT-like DNA-binding domain containing 2
chr5_+_110559603	0.35	ENST00000512453.1	CAMK4	calcium/calmodulin-dependent protein kinase IV
chr11_-_82708519	0.35	ENST00000534301.1	RAB30	RAB30, member RAS oncogene family
chr19_-_55691377	0.35	ENST00000589172.1	SYT5	synaptotagmin V
chr3_-_66551397	0.35	ENST00000383703.3	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr7_+_99717230	0.34	ENST00000262932.3	CNPY4	canopy FGF signaling regulator 4
chr14_+_50999744	0.34	ENST00000441560.2	ATL1	atlastin GTPase 1
chr12_+_52643077	0.34	ENST00000553310.2 ENST00000544024.1	KRT86	keratin 86
chr1_-_79472365	0.34	ENST00000370742.3	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1
chr2_+_173940163	0.33	ENST00000539448.1	MLTK	Mitogen-activated protein kinase kinase kinase MLT
chr9_+_2157655	0.33	ENST00000452193.1	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_204192942	0.33	ENST00000295851.5 ENST00000261017.5	ABI2	abl-interactor 2
chr2_+_62132800	0.33	ENST00000538736.1	COMMD1	copper metabolism (Murr1) domain containing 1
chr6_-_41168920	0.33	ENST00000483722.1	TREML2	triggering receptor expressed on myeloid cells-like 2
chr15_+_63481668	0.33	ENST00000321437.4 ENST00000559006.1 ENST00000448330.2	RAB8B	RAB8B, member RAS oncogene family
chr6_-_154751629	0.33	ENST00000424998.1	CNKSR3	CNKSR family member 3
chr6_+_30524663	0.32	ENST00000376560.3	PRR3	proline rich 3
chrX_+_36065053	0.32	ENST00000313548.4	CHDC2	calponin homology domain containing 2
chr12_+_66217911	0.32	ENST00000403681.2	HMGA2	high mobility group AT-hook 2
chr5_-_159846399	0.32	ENST00000297151.4	SLU7	SLU7 splicing factor homolog (S. cerevisiae)
chr21_-_31869451	0.32	ENST00000334058.2	KRTAP19-4	keratin associated protein 19-4
chr3_-_73673991	0.32	ENST00000308537.4 ENST00000263666.4	PDZRN3	PDZ domain containing ring finger 3
chr15_-_95870310	0.32	ENST00000508732.2	CTD-2536I1.1	CTD-2536I1.1
chr1_-_54405773	0.32	ENST00000371376.1	HSPB11	heat shock protein family B (small), member 11
chr1_+_90098606	0.32	ENST00000370454.4	LRRC8C	leucine rich repeat containing 8 family, member C
chr5_+_137774706	0.32	ENST00000378339.2 ENST00000254901.5 ENST00000506158.1	REEP2	receptor accessory protein 2
chr14_+_88471468	0.31	ENST00000267549.3	GPR65	G protein-coupled receptor 65
chr12_+_75874984	0.31	ENST00000550491.1	GLIPR1	GLI pathogenesis-related 1
chr12_+_79439405	0.31	ENST00000552744.1	SYT1	synaptotagmin I
chr5_+_178986693	0.31	ENST00000437570.2 ENST00000393438.2	RUFY1	RUN and FYVE domain containing 1
chr13_+_24144796	0.31	ENST00000403372.2	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr2_+_201997492	0.31	ENST00000494258.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr14_-_61190754	0.31	ENST00000216513.4	SIX4	SIX homeobox 4
chr12_+_71833550	0.31	ENST00000266674.5	LGR5	leucine-rich repeat containing G protein-coupled receptor 5
chr6_+_72926145	0.31	ENST00000425662.2 ENST00000453976.2	RIMS1	regulating synaptic membrane exocytosis 1
chr11_-_57283159	0.31	ENST00000533263.1 ENST00000278426.3	SLC43A1	solute carrier family 43 (amino acid system L transporter), member 1
chr5_+_169780485	0.30	ENST00000377360.4	KCNIP1	Kv channel interacting protein 1
chr20_-_39928756	0.30	ENST00000432768.2	ZHX3	zinc fingers and homeoboxes 3
chr12_-_76817036	0.30	ENST00000546946.1	OSBPL8	oxysterol binding protein-like 8
chr18_+_32455201	0.30	ENST00000590831.2	DTNA	dystrobrevin, alpha
chr12_-_49582978	0.30	ENST00000301071.7	TUBA1A	tubulin, alpha 1a
chrX_-_99665262	0.30	ENST00000373034.4 ENST00000255531.7	PCDH19	protocadherin 19
chr2_+_170683942	0.30	ENST00000272793.5	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr8_-_67525473	0.30	ENST00000522677.3	MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1
chr12_+_7023491	0.30	ENST00000541477.1 ENST00000229277.1	ENO2	enolase 2 (gamma, neuronal)
chr16_-_2260834	0.30	ENST00000562360.1 ENST00000566018.1	BRICD5	BRICHOS domain containing 5
chr15_-_55700522	0.30	ENST00000564092.1 ENST00000310958.6	CCPG1	cell cycle progression 1
chr12_-_10978957	0.29	ENST00000240619.2	TAS2R10	taste receptor, type 2, member 10
chr17_-_39623681	0.29	ENST00000225899.3	KRT32	keratin 32
chr10_-_90712520	0.29	ENST00000224784.6	ACTA2	actin, alpha 2, smooth muscle, aorta
chr1_+_178310581	0.29	ENST00000462775.1	RASAL2	RAS protein activator like 2
chr3_-_128690173	0.29	ENST00000508239.1	RP11-723O4.6	Uncharacterized protein FLJ43738
chr19_+_55795493	0.29	ENST00000309383.1	BRSK1	BR serine/threonine kinase 1
chr11_+_124824000	0.29	ENST00000529051.1 ENST00000344762.5	CCDC15	coiled-coil domain containing 15
chr7_+_73082152	0.29	ENST00000324941.4 ENST00000451519.1	VPS37D	vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr9_-_137809718	0.29	ENST00000371806.3	FCN1	ficolin (collagen/fibrinogen domain containing) 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	8.8	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4	2.8	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3	3.6	GO:0034465	response to carbon monoxide(GO:0034465)
0.3	0.9	GO:0046110	xanthine metabolic process(GO:0046110)
0.3	0.8	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.3	2.4	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2	0.7	GO:0034059	response to anoxia(GO:0034059)
0.2	2.0	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2	0.6	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.2	0.8	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	1.2	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.2	0.9	GO:0072313	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2	0.5	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2	0.5	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.1	0.7	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	0.9	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	0.9	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1	0.6	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	2.7	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	0.7	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.6	GO:0046449	creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.1	0.6	GO:0031103	axon regeneration(GO:0031103) regulation of axon regeneration(GO:0048679) negative regulation of axon regeneration(GO:0048681) regulation of neuron projection regeneration(GO:0070570) negative regulation of neuron projection regeneration(GO:0070571)
0.1	0.5	GO:1904647	response to rotenone(GO:1904647)
0.1	0.3	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.4	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	0.3	GO:0072095	regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.1	0.5	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.6	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	0.5	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.8	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.1	0.3	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	0.4	GO:0018032	protein amidation(GO:0018032)
0.1	0.3	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1	0.5	GO:2000683	regulation of cellular response to X-ray(GO:2000683)
0.1	0.3	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1	0.2	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.1	0.2	GO:0006500	N-terminal protein palmitoylation(GO:0006500)
0.1	1.7	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:2001197	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1	0.1	GO:0043396	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1	0.2	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	0.3	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.3	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.4	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.1	0.3	GO:0034959	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1	0.6	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.5	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	1.1	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	0.6	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.6	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.4	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.3	GO:0090131	mesenchyme migration(GO:0090131)
0.1	1.0	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.5	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.6	GO:0015889	cobalamin transport(GO:0015889)
0.1	1.6	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.1	0.4	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	0.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.2	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1	0.2	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.4	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.1	0.4	GO:0018344	protein geranylgeranylation(GO:0018344)
0.1	0.2	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1	0.2	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0	0.4	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:1903367	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0	0.1	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0	0.5	GO:0071313	cellular response to caffeine(GO:0071313)
0.0	0.3	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	1.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	1.8	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.0	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.0	0.3	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.3	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.0	0.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.0	2.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0072619	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0	0.4	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.0	0.3	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.1	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0	0.4	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.7	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:1990822	L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0	0.2	GO:0070141	response to UV-A(GO:0070141)
0.0	0.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.1	GO:0060434	bronchus morphogenesis(GO:0060434)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0003363	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0039019	pronephric nephron development(GO:0039019)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.7	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.2	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.0	0.2	GO:0051289	protein homotetramerization(GO:0051289)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.2	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.0	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.1	GO:0033128	negative regulation of histone phosphorylation(GO:0033128)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.2	GO:0048241	epinephrine transport(GO:0048241)
0.0	0.1	GO:0033561	regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0	0.1	GO:0045337	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0	0.5	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.0	0.4	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	1.0	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.5	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0	0.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.3	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.0	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0046462	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0	0.2	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	0.2	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.0	0.5	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0061143	alveolar primary septum development(GO:0061143)
0.0	0.3	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.5	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.3	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0	0.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.6	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.1	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	0.1	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.0	0.1	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0	0.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.2	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0000066	mitochondrial ornithine transport(GO:0000066)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0	0.2	GO:0042182	ketone catabolic process(GO:0042182)
0.0	0.6	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:0090317	negative regulation of intracellular protein transport(GO:0090317)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0	0.2	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.2	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.1	GO:0002836	positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.2	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.7	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.2	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.0	0.0	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
0.0	0.5	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:2000439	monocyte extravasation(GO:0035696) regulation of eosinophil degranulation(GO:0043309) negative regulation of eosinophil activation(GO:1902567) regulation of monocyte extravasation(GO:2000437) positive regulation of monocyte extravasation(GO:2000439)
0.0	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.2	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.2	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.0	0.2	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.3	GO:0042476	odontogenesis(GO:0042476)
0.0	0.2	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.1	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.0	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.7	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	0.0	GO:0032899	neurotrophin production(GO:0032898) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0	0.1	GO:2001252	positive regulation of chromosome organization(GO:2001252)
0.0	0.3	GO:2000404	regulation of T cell migration(GO:2000404)
0.0	0.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.0	0.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.2	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.6	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	2.6	GO:0034332	adherens junction organization(GO:0034332)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.5	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.3	GO:0007605	sensory perception of sound(GO:0007605) sensory perception of mechanical stimulus(GO:0050954)
0.0	0.1	GO:0090119	vesicle-mediated cholesterol transport(GO:0090119)
0.0	0.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.1	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.0	0.0	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.2	GO:0070986	left/right axis specification(GO:0070986)
0.0	1.3	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.2	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.0	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0	0.5	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.2	GO:0044241	lipid digestion(GO:0044241)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.4	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.4	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.2	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.4	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.0	GO:0072102	glomerulus morphogenesis(GO:0072102)
0.0	0.2	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.2	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.7	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.0	0.1	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	0.9	GO:0005608	laminin-3 complex(GO:0005608)
0.3	0.8	GO:0005588	collagen type V trimer(GO:0005588)
0.2	2.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0032002	interleukin-28 receptor complex(GO:0032002)
0.1	0.5	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	0.4	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	0.5	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.4	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	2.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1	0.6	GO:0036128	CatSper complex(GO:0036128)
0.1	0.6	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.5	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.4	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.1	0.5	GO:1990769	proximal neuron projection(GO:1990769)
0.1	0.6	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.3	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
0.1	0.2	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.1	0.9	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.4	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	0.2	GO:0005606	laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607)
0.1	0.9	GO:0030478	actin cap(GO:0030478)
0.1	0.2	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	1.5	GO:0071565	nBAF complex(GO:0071565)
0.1	0.3	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.1	0.4	GO:0002177	manchette(GO:0002177)
0.0	0.8	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.6	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.2	GO:0035370	UBC13-UEV1A complex(GO:0035370)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	0.6	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.2	GO:0089701	U2AF(GO:0089701)
0.0	0.5	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0	0.2	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0	0.2	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.0	0.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	1.0	GO:0043218	compact myelin(GO:0043218)
0.0	0.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.2	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0051286	cell tip(GO:0051286)
0.0	3.4	GO:0005901	caveola(GO:0005901)
0.0	0.4	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.0	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.0	2.2	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.5	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0001534	radial spoke(GO:0001534)
0.0	0.1	GO:0032798	Swi5-Sfr1 complex(GO:0032798)
0.0	0.3	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.4	GO:0031526	brush border membrane(GO:0031526)
0.0	0.2	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.5	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0005656	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0	0.0	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	1.7	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.6	GO:0005903	brush border(GO:0005903)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	1.5	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.8	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.1	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	2.2	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.5	3.6	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.3	2.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.3	1.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3	1.6	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2	0.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	0.8	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.2	1.2	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.2	0.5	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.2	0.6	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1	2.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.4	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	0.6	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.4	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	9.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.4	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1	0.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.3	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1	0.5	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	0.7	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.3	GO:0035501	MH1 domain binding(GO:0035501)
0.1	0.3	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.1	0.2	GO:0017129	triglyceride binding(GO:0017129)
0.1	0.5	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1	0.3	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.3	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	0.2	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.5	GO:0043559	insulin binding(GO:0043559)
0.1	0.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	2.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	1.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.2	GO:0052836	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1	1.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	0.4	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.1	0.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0047783	steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0	0.9	GO:0051787	misfolded protein binding(GO:0051787)
0.0	1.0	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.4	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.6	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.2	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0	1.0	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.3	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.5	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0	0.9	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.6	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0	1.0	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.0	0.2	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.3	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0045518	interleukin-22 receptor binding(GO:0045518)
0.0	0.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.2	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0	0.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.5	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0004998	transferrin receptor activity(GO:0004998)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.0	0.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0031716	calcitonin receptor binding(GO:0031716)
0.0	1.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	0.0	GO:0070404	NADH binding(GO:0070404)
0.0	0.1	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.7	GO:0005521	lamin binding(GO:0005521)
0.0	0.3	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.4	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.2	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.1	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.1	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.2	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	0.1	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0	0.1	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.2	GO:0042731	PH domain binding(GO:0042731)
0.0	0.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.3	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.5	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.4	GO:0008494	translation activator activity(GO:0008494)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.8	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	1.2	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	1.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.4	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	1.0	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0004743	pyruvate kinase activity(GO:0004743)
0.0	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.9	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0051870	methotrexate binding(GO:0051870)
0.0	0.1	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.2	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	1.4	GO:0005179	hormone activity(GO:0005179)
0.0	1.8	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.0	GO:0090541	MIT domain binding(GO:0090541)
0.0	0.1	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0	0.1	GO:0046527	glucosyltransferase activity(GO:0046527)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	1.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	2.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	2.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.5	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.8	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.1	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	2.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	2.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.7	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	2.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	2.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	1.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	1.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.6	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors