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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GFI1

Z-value: 0.58

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Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
GFI1
ENSG00000162676.7 GFI1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1hg19_v2_chr1_-_92952433_92952489,
hg19_v2_chr1_-_92951607_92951661,
hg19_v2_chr1_-_92949505_92949543		0.801.7e-02Click!

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_21452804 1.06 ENST00000269217.6
 LAMA3
 laminin, alpha 3
chr18_+_21452964 1.05 ENST00000587184.1
 LAMA3
 laminin, alpha 3
chr1_-_242612779 0.91 ENST00000427495.1
 PLD5
 phospholipase D family, member 5
chr20_+_58179582 0.69 ENST00000371015.1
ENST00000395639.4
 PHACTR3
 phosphatase and actin regulator 3
chr8_-_57232656 0.63 ENST00000396721.2
 SDR16C5
 short chain dehydrogenase/reductase family 16C, member 5
chr2_+_17721230 0.59 ENST00000457525.1
 VSNL1
 visinin-like 1
chr18_+_29027696 0.58 ENST00000257189.4
 DSG3
 desmoglein 3
chr19_-_10687907 0.56 ENST00000589348.1
 AP1M2
 adaptor-related protein complex 1, mu 2 subunit
chr5_+_36608422 0.55 ENST00000381918.3
 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_17721920 0.49 ENST00000295156.4
 VSNL1
 visinin-like 1
chr11_-_5323226 0.48 ENST00000380224.1
 OR51B4
 olfactory receptor, family 51, subfamily B, member 4
chr19_-_43969796 0.46 ENST00000244333.3
 LYPD3
 LY6/PLAUR domain containing 3
chr12_+_44229846 0.45 ENST00000551577.1
ENST00000266534.3
 TMEM117
 transmembrane protein 117
chr19_-_10687948 0.44 ENST00000592285.1
 AP1M2
 adaptor-related protein complex 1, mu 2 subunit
chr7_+_16793160 0.41 ENST00000262067.4
 TSPAN13
 tetraspanin 13
chr19_-_10687983 0.40 ENST00000587069.1
 AP1M2
 adaptor-related protein complex 1, mu 2 subunit
chr19_-_55660561 0.36 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
 TNNT1
 troponin T type 1 (skeletal, slow)
chr14_+_21525981 0.33 ENST00000308227.2
 RNASE8
 ribonuclease, RNase A family, 8
chr7_+_86273218 0.33 ENST00000361669.2
 GRM3
 glutamate receptor, metabotropic 3
chr5_+_140261703 0.32 ENST00000409494.1
ENST00000289272.2
 PCDHA13
 protocadherin alpha 13
chr13_+_113623509 0.31 ENST00000535094.2
 MCF2L
 MCF.2 cell line derived transforming sequence-like
chr1_+_62439037 0.30 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chrX_+_49832231 0.30 ENST00000376108.3
 CLCN5
 chloride channel, voltage-sensitive 5
chr1_-_147232669 0.29 ENST00000369237.1
 GJA5
 gap junction protein, alpha 5, 40kDa
chr15_-_52587945 0.29 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
 MYO5C
 myosin VC
chr2_+_85360499 0.29 ENST00000282111.3
 TCF7L1
 transcription factor 7-like 1 (T-cell specific, HMG-box)
chr17_-_56494882 0.29 ENST00000584437.1
 RNF43
 ring finger protein 43
chr17_-_56494713 0.29 ENST00000407977.2
 RNF43
 ring finger protein 43
chr19_-_16045220 0.29 ENST00000326742.8
 CYP4F11
 cytochrome P450, family 4, subfamily F, polypeptide 11
chr17_-_56494908 0.29 ENST00000577716.1
 RNF43
 ring finger protein 43
chr17_-_39780819 0.28 ENST00000311208.8
 KRT17
 keratin 17
chr4_+_41937131 0.28 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
 TMEM33
 transmembrane protein 33
chr19_-_16045665 0.28 ENST00000248041.8
 CYP4F11
 cytochrome P450, family 4, subfamily F, polypeptide 11
chr14_-_22005062 0.27 ENST00000317492.5
 SALL2
 spalt-like transcription factor 2
chr19_-_16045619 0.27 ENST00000402119.4
 CYP4F11
 cytochrome P450, family 4, subfamily F, polypeptide 11
chr14_-_22005343 0.27 ENST00000327430.3
 SALL2
 spalt-like transcription factor 2
chr12_+_56732658 0.26 ENST00000228534.4
 IL23A
 interleukin 23, alpha subunit p19
chr2_+_103378472 0.24 ENST00000412401.2
 TMEM182
 transmembrane protein 182
chr10_-_10836865 0.24 ENST00000446372.2
 SFTA1P
 surfactant associated 1, pseudogene
chr16_+_4838412 0.24 ENST00000589327.1
 SMIM22
 small integral membrane protein 22
chr8_-_145642267 0.24 ENST00000301305.3
 SLC39A4
 solute carrier family 39 (zinc transporter), member 4
chr19_-_43099070 0.23 ENST00000244336.5
 CEACAM8
 carcinoembryonic antigen-related cell adhesion molecule 8
chr5_+_147582387 0.23 ENST00000325630.2
 SPINK6
 serine peptidase inhibitor, Kazal type 6
chr5_+_148206156 0.23 ENST00000305988.4
 ADRB2
 adrenoceptor beta 2, surface
chr3_-_33686743 0.23 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr1_+_156254070 0.23 ENST00000405535.2
ENST00000456810.1
 TMEM79
 transmembrane protein 79
chr5_-_35230434 0.22 ENST00000504500.1
 PRLR
 prolactin receptor
chr4_+_89299885 0.22 ENST00000380265.5
ENST00000273960.3
 HERC6
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr10_+_24498060 0.22 ENST00000376454.3
ENST00000376452.3
 KIAA1217
 KIAA1217
chr16_+_4838393 0.22 ENST00000589721.1
 SMIM22
 small integral membrane protein 22
chr10_+_24755416 0.22 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
 KIAA1217
 KIAA1217
chr10_-_10836919 0.22 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
 SFTA1P
 surfactant associated 1, pseudogene
chr9_-_117150243 0.22 ENST00000374088.3
 AKNA
 AT-hook transcription factor
chr4_+_89299994 0.22 ENST00000264346.7
 HERC6
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr5_-_78809950 0.21 ENST00000334082.6
 HOMER1
 homer homolog 1 (Drosophila)
chr18_-_78005231 0.21 ENST00000470488.2
ENST00000353265.3
 PARD6G
 par-6 family cell polarity regulator gamma
chr1_-_25291475 0.21 ENST00000338888.3
ENST00000399916.1
 RUNX3
 runt-related transcription factor 3
chr8_-_145641864 0.20 ENST00000276833.5
 SLC39A4
 solute carrier family 39 (zinc transporter), member 4
chr16_+_82090028 0.20 ENST00000568090.1
 HSD17B2
 hydroxysteroid (17-beta) dehydrogenase 2
chrX_-_133792480 0.20 ENST00000359237.4
 PLAC1
 placenta-specific 1
chr14_+_71108460 0.20 ENST00000256367.2
 TTC9
 tetratricopeptide repeat domain 9
chr15_+_92397051 0.20 ENST00000424469.2
 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
chr7_+_65670186 0.19 ENST00000304842.5
ENST00000442120.1
 TPST1
 tyrosylprotein sulfotransferase 1
chr18_+_55711575 0.19 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_34642656 0.19 ENST00000257831.3
ENST00000450654.2
 EHF
 ets homologous factor
chr1_-_10856694 0.19 ENST00000377022.3
ENST00000344008.5
 CASZ1
 castor zinc finger 1
chr9_+_71939488 0.18 ENST00000455972.1
 FAM189A2
 family with sequence similarity 189, member A2
chr3_-_33686925 0.18 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
 CLASP2
 cytoplasmic linker associated protein 2
chr18_-_53257027 0.18 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
 TCF4
 transcription factor 4
chr6_-_143771799 0.18 ENST00000237283.8
 ADAT2
 adenosine deaminase, tRNA-specific 2
chrX_+_138612889 0.18 ENST00000218099.2
ENST00000394090.2
 F9
 coagulation factor IX
chr6_-_28554977 0.18 ENST00000452236.2
 SCAND3
 SCAN domain containing 3
chr6_+_25279651 0.17 ENST00000329474.6
 LRRC16A
 leucine rich repeat containing 16A
chr8_-_124054484 0.17 ENST00000419562.2
 DERL1
 derlin 1
chr2_+_148602058 0.17 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
 ACVR2A
 activin A receptor, type IIA
chr8_-_124054362 0.17 ENST00000405944.3
 DERL1
 derlin 1
chr19_+_41281416 0.16 ENST00000597140.1
 MIA
 melanoma inhibitory activity
chr8_-_124054587 0.16 ENST00000259512.4
 DERL1
 derlin 1
chr2_-_238499725 0.16 ENST00000264601.3
 RAB17
 RAB17, member RAS oncogene family
chr5_+_35856951 0.16 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
 IL7R
 interleukin 7 receptor
chr17_+_3539998 0.16 ENST00000452111.1
ENST00000574776.1
ENST00000441220.2
ENST00000414524.2
 CTNS
 cystinosin, lysosomal cystine transporter
chr4_-_80994619 0.15 ENST00000404191.1
 ANTXR2
 anthrax toxin receptor 2
chr8_+_75736761 0.15 ENST00000260113.2
 PI15
 peptidase inhibitor 15
chr19_-_13227463 0.15 ENST00000437766.1
ENST00000221504.8
 TRMT1
 tRNA methyltransferase 1 homolog (S. cerevisiae)
chr20_+_55204351 0.15 ENST00000201031.2
 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_+_140174429 0.15 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
 PCDHA2
 protocadherin alpha 2
chr14_-_93214915 0.15 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
 LGMN
 legumain
chr19_+_41281282 0.15 ENST00000263369.3
 MIA
 melanoma inhibitory activity
chr2_-_69180083 0.15 ENST00000328895.4
 GKN2
 gastrokine 2
chr1_+_81771806 0.14 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr14_-_93214988 0.14 ENST00000557434.1
ENST00000393218.2
ENST00000334869.4
 LGMN
 legumain
chr6_+_45296391 0.14 ENST00000371436.6
ENST00000576263.1
 RUNX2
 runt-related transcription factor 2
chr12_+_41831485 0.14 ENST00000539469.2
ENST00000298919.7
 PDZRN4
 PDZ domain containing ring finger 4
chr6_+_29364416 0.14 ENST00000383555.2
 OR12D2
 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr19_-_7797045 0.14 ENST00000328853.5
 CLEC4G
 C-type lectin domain family 4, member G
chr15_+_92396920 0.13 ENST00000318445.6
 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
chr4_-_90756769 0.13 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr6_-_10412600 0.13 ENST00000379608.3
 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr12_+_113354341 0.13 ENST00000553152.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_-_13227534 0.13 ENST00000588229.1
ENST00000357720.4
 TRMT1
 tRNA methyltransferase 1 homolog (S. cerevisiae)
chr19_+_41281060 0.13 ENST00000594436.1
ENST00000597784.1
 MIA
 melanoma inhibitory activity
chr2_+_153574428 0.13 ENST00000326446.5
 ARL6IP6
 ADP-ribosylation-like factor 6 interacting protein 6
chr6_+_31795506 0.13 ENST00000375650.3
 HSPA1B
 heat shock 70kDa protein 1B
chr13_-_46756351 0.13 ENST00000323076.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_66701319 0.12 ENST00000379419.4
 PDE7A
 phosphodiesterase 7A
chr17_-_41836153 0.12 ENST00000301691.2
 SOST
 sclerostin
chr8_+_42010464 0.12 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
 AP3M2
 adaptor-related protein complex 3, mu 2 subunit
chr4_-_103266626 0.12 ENST00000356736.4
 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
chr17_-_39280419 0.12 ENST00000394014.1
 KRTAP4-12
 keratin associated protein 4-12
chr2_-_9143786 0.12 ENST00000462696.1
ENST00000305997.3
 MBOAT2
 membrane bound O-acyltransferase domain containing 2
chr5_+_147582348 0.12 ENST00000514389.1
 SPINK6
 serine peptidase inhibitor, Kazal type 6
chr11_-_117748138 0.12 ENST00000527717.1
 FXYD6
 FXYD domain containing ion transport regulator 6
chr2_-_160472952 0.12 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
chr13_+_47127322 0.12 ENST00000389798.3
 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
chr17_-_39580775 0.12 ENST00000225550.3
 KRT37
 keratin 37
chr9_-_34376851 0.12 ENST00000297625.7
 KIAA1161
 KIAA1161
chr7_-_71912046 0.12 ENST00000395276.2
ENST00000431984.1
 CALN1
 calneuron 1
chr7_+_130020932 0.12 ENST00000484324.1
 CPA1
 carboxypeptidase A1 (pancreatic)
chr12_-_95510743 0.12 ENST00000551521.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr7_-_121944491 0.12 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
 FEZF1
 FEZ family zinc finger 1
chr8_+_118532937 0.12 ENST00000297347.3
 MED30
 mediator complex subunit 30
chr2_+_105050794 0.12 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
 AC013402.2
 long intergenic non-protein coding RNA 1102
chr2_+_234104079 0.12 ENST00000417661.1
 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
chr20_-_23066953 0.11 ENST00000246006.4
 CD93
 CD93 molecule
chr11_+_59522532 0.11 ENST00000337979.4
ENST00000535361.1
 STX3
 syntaxin 3
chr2_-_160473114 0.11 ENST00000392783.2
 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
chr14_+_22771851 0.11 ENST00000390466.1
 TRAV39
 T cell receptor alpha variable 39
chr11_+_2323236 0.11 ENST00000182290.4
 TSPAN32
 tetraspanin 32
chr7_+_23636992 0.11 ENST00000307471.3
ENST00000409765.1
 CCDC126
 coiled-coil domain containing 126
chr10_-_13523073 0.11 ENST00000440282.1
 BEND7
 BEN domain containing 7
chr2_+_11696464 0.11 ENST00000234142.5
 GREB1
 growth regulation by estrogen in breast cancer 1
chr11_-_62752162 0.11 ENST00000458333.2
ENST00000421062.2
 SLC22A6
 solute carrier family 22 (organic anion transporter), member 6
chr3_-_66024213 0.11 ENST00000483466.1
 MAGI1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
chr5_+_176784837 0.11 ENST00000408923.3
 RGS14
 regulator of G-protein signaling 14
chr2_+_162272605 0.11 ENST00000389554.3
 TBR1
 T-box, brain, 1
chr6_+_42584847 0.11 ENST00000372883.3
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr20_+_43935474 0.11 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
 RBPJL
 recombination signal binding protein for immunoglobulin kappa J region-like
chr1_-_155947951 0.11 ENST00000313695.7
ENST00000497907.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_-_195619579 0.11 ENST00000428187.1
 TNK2
 tyrosine kinase, non-receptor, 2
chr3_-_119813264 0.11 ENST00000264235.8
 GSK3B
 glycogen synthase kinase 3 beta
chr4_+_56815102 0.11 ENST00000257287.4
 CEP135
 centrosomal protein 135kDa
chr14_-_95624227 0.11 ENST00000526495.1
 DICER1
 dicer 1, ribonuclease type III
chr18_-_53177984 0.10 ENST00000543082.1
 TCF4
 transcription factor 4
chrX_-_138914394 0.10 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
 ATP11C
 ATPase, class VI, type 11C
chr13_-_103719196 0.10 ENST00000245312.3
 SLC10A2
 solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr8_+_133931648 0.10 ENST00000519178.1
ENST00000542445.1
 TG
 thyroglobulin
chr11_+_93861993 0.10 ENST00000227638.3
ENST00000436171.2
 PANX1
 pannexin 1
chr11_-_72433346 0.09 ENST00000334211.8
 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr15_+_42131011 0.09 ENST00000458483.1
 PLA2G4B
 phospholipase A2, group IVB (cytosolic)
chr8_+_95835438 0.09 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
 INTS8
 integrator complex subunit 8
chr17_+_27573875 0.09 ENST00000225387.3
 CRYBA1
 crystallin, beta A1
chr12_+_81101277 0.09 ENST00000228641.3
 MYF6
 myogenic factor 6 (herculin)
chr9_-_112260531 0.09 ENST00000374541.2
ENST00000262539.3
 PTPN3
 protein tyrosine phosphatase, non-receptor type 3
chr8_+_144451039 0.09 ENST00000289013.6
 RHPN1
 rhophilin, Rho GTPase binding protein 1
chr17_+_39261584 0.09 ENST00000391415.1
 KRTAP4-9
 keratin associated protein 4-9
chr18_-_59854203 0.09 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
 PIGN
 phosphatidylinositol glycan anchor biosynthesis, class N
chr17_+_68071389 0.09 ENST00000283936.1
ENST00000392671.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_135271260 0.09 ENST00000265605.2
 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
chr6_+_21593972 0.09 ENST00000244745.1
ENST00000543472.1
 SOX4
 SRY (sex determining region Y)-box 4
chr18_-_19283649 0.09 ENST00000584464.1
ENST00000578270.1
 ABHD3
 abhydrolase domain containing 3
chr6_-_135271219 0.09 ENST00000367847.2
ENST00000367845.2
 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
chr17_+_47448102 0.09 ENST00000576461.1
 RP11-81K2.1
 Uncharacterized protein
chr19_+_55477711 0.09 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
 NLRP2
 NLR family, pyrin domain containing 2
chr17_+_11924129 0.09 ENST00000353533.5
ENST00000415385.3
 MAP2K4
 mitogen-activated protein kinase kinase 4
chr1_-_153348067 0.09 ENST00000368737.3
 S100A12
 S100 calcium binding protein A12
chr12_+_113659234 0.09 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
 TPCN1
 two pore segment channel 1
chr2_+_27799389 0.09 ENST00000408964.2
 C2orf16
 chromosome 2 open reading frame 16
chr11_+_85956182 0.09 ENST00000327320.4
ENST00000351625.6
ENST00000534595.1
 EED
 embryonic ectoderm development
chr17_+_3539744 0.08 ENST00000046640.3
ENST00000381870.3
 CTNS
 cystinosin, lysosomal cystine transporter
chr2_-_231989808 0.08 ENST00000258400.3
 HTR2B
 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr1_+_46713404 0.08 ENST00000371975.4
ENST00000469835.1
 RAD54L
 RAD54-like (S. cerevisiae)
chr1_+_46713357 0.08 ENST00000442598.1
 RAD54L
 RAD54-like (S. cerevisiae)
chr1_+_173793641 0.08 ENST00000361951.4
 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
chrX_+_84499081 0.08 ENST00000276123.3
 ZNF711
 zinc finger protein 711
chr1_+_173793777 0.08 ENST00000239457.5
 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
chr5_+_178368186 0.08 ENST00000320129.3
ENST00000519564.1
 ZNF454
 zinc finger protein 454
chr11_-_94964354 0.08 ENST00000536441.1
 SESN3
 sestrin 3
chr7_+_23637118 0.08 ENST00000448353.1
 CCDC126
 coiled-coil domain containing 126
chr12_+_50017327 0.08 ENST00000261897.1
 PRPF40B
 PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr4_-_96470108 0.08 ENST00000513796.1
 UNC5C
 unc-5 homolog C (C. elegans)
chr21_-_36421535 0.08 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
 RUNX1
 runt-related transcription factor 1
chr6_+_30294612 0.08 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
 TRIM39
 tripartite motif containing 39
chr10_+_118083919 0.08 ENST00000333254.3
 CCDC172
 coiled-coil domain containing 172
chr19_+_6887571 0.08 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
 EMR1
 egf-like module containing, mucin-like, hormone receptor-like 1
chr3_-_196910721 0.08 ENST00000443183.1
 DLG1
 discs, large homolog 1 (Drosophila)
chr6_-_146285455 0.08 ENST00000367505.2
 SHPRH
 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr5_-_141338627 0.08 ENST00000231484.3
 PCDH12
 protocadherin 12
chr17_+_68071458 0.08 ENST00000589377.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr18_-_35145728 0.08 ENST00000361795.5
ENST00000603232.1
 CELF4
 CUGBP, Elav-like family member 4
chr12_-_113658892 0.08 ENST00000299732.2
ENST00000416617.2
 IQCD
 IQ motif containing D
chr6_+_30457244 0.07 ENST00000376630.4
 HLA-E
 major histocompatibility complex, class I, E
chr6_+_160327974 0.07 ENST00000252660.4
 MAS1
 MAS1 oncogene
chr16_-_70323422 0.07 ENST00000261772.8
 AARS
 alanyl-tRNA synthetase
chr10_+_6392278 0.07 ENST00000391437.1
 DKFZP667F0711
 DKFZP667F0711
chr1_-_115238207 0.07 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
 AMPD1
 adenosine monophosphate deaminase 1
chr2_-_69180012 0.07 ENST00000481498.1
 GKN2
 gastrokine 2
chr3_+_1134260 0.07 ENST00000446702.2
ENST00000539053.1
ENST00000350110.2
 CNTN6
 contactin 6
chr5_-_88179302 0.07 ENST00000504921.2
 MEF2C
 myocyte enhancer factor 2C
chr1_+_209859510 0.07 ENST00000367028.2
ENST00000261465.1
 HSD11B1
 hydroxysteroid (11-beta) dehydrogenase 1
chr3_-_158450475 0.07 ENST00000237696.5
 RARRES1
 retinoic acid receptor responder (tazarotene induced) 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.3 GO:0098905 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.5 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.2 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.3 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.8 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:1904339 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0070997 neuron death(GO:0070997)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 1.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0032759 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.1 GO:0035910 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 1.1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.0 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:1903781 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of cardiac conduction(GO:1903781)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 1.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins