ISMARA results: GZF1

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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GZF1

Z-value: 0.77

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Transcription factors associated with GZF1

Gene Symbol	Gene ID	Gene Info
GZF1 Ensembl NCBI GeneCards UniProt	ENSG00000125812.11	GZF1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GZF1	hg19_v2_chr20_+_23342783_23342957	0.59	1.3e-01	Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

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Top targets:

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Promoter	Score	Transcript	Gene	Gene Info
chr14_-_92413353	1.79	ENST00000556154.1	FBLN5	fibulin 5
chr14_-_92413727	1.55	ENST00000267620.10	FBLN5	fibulin 5
chr5_+_92919043	1.07	ENST00000327111.3	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr14_-_52535712	0.92	ENST00000216286.5 ENST00000541773.1	NID2	nidogen 2 (osteonidogen)
chr14_+_101292445	0.72	ENST00000429159.2 ENST00000520714.1 ENST00000522771.2 ENST00000424076.3 ENST00000423456.1 ENST00000521404.1 ENST00000556736.1 ENST00000451743.2 ENST00000398518.2 ENST00000554639.1 ENST00000452120.2 ENST00000519709.1 ENST00000412736.2	MEG3	maternally expressed 3 (non-protein coding)
chr1_+_79115503	0.64	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44	interferon-induced protein 44
chr3_-_114035026	0.62	ENST00000570269.1	RP11-553L6.5	RP11-553L6.5
chr1_-_144994909	0.61	ENST00000369347.4 ENST00000369354.3	PDE4DIP	phosphodiesterase 4D interacting protein
chrX_+_54835493	0.60	ENST00000396224.1	MAGED2	melanoma antigen family D, 2
chr4_-_89619386	0.60	ENST00000323061.5	NAP1L5	nucleosome assembly protein 1-like 5

Showing 1 to 10 of 57 entries

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.9	GO:0071711	basement membrane organization(GO:0071711)
0.1	0.6	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	0.5	GO:0060435	bronchiole development(GO:0060435)
0.1	0.3	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.2	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:1901079	positive regulation of relaxation of muscle(GO:1901079)
0.0	0.1	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Showing 1 to 10 of 12 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.3	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.3	GO:0005178	integrin binding(GO:0005178)
0.1	1.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.0	0.1	GO:0047661	racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)

Showing 1 to 7 of 7 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Showing 1 to 2 of 2 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway

Showing 1 to 1 of 1 entries

Results for GZF1

Z-value: 0.77

Motif logo

Transcription factors associated with GZF1

Activity-expression correlation:

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: