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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GZF1

Z-value: 0.77

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
ENSG00000125812.11 GZF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_233429570.591.3e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_92413353 1.79 ENST00000556154.1
FBLN5
fibulin 5
chr14_-_92413727 1.55 ENST00000267620.10
FBLN5
fibulin 5
chr5_+_92919043 1.07 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr14_-_52535712 0.92 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr14_+_101292445 0.72 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
MEG3
maternally expressed 3 (non-protein coding)
chr1_+_79115503 0.64 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr3_-_114035026 0.62 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr1_-_144994909 0.61 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chrX_+_54835493 0.60 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr4_-_89619386 0.60 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr1_-_144995074 0.55 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr7_-_27183263 0.52 ENST00000222726.3
HOXA5
homeobox A5
chr1_+_26606608 0.45 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_144995002 0.42 ENST00000369356.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_44384291 0.42 ENST00000324394.6
ZNF404
zinc finger protein 404
chrX_+_102883620 0.41 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr6_+_30524663 0.37 ENST00000376560.3
PRR3
proline rich 3
chr6_+_30525051 0.34 ENST00000376557.3
PRR3
proline rich 3
chr3_-_87040233 0.33 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr16_+_86612112 0.31 ENST00000320241.3
FOXL1
forkhead box L1
chr12_+_107168418 0.30 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr20_-_31331212 0.29 ENST00000474815.2
ENST00000446419.2
COMMD7
COMM domain containing 7
chr1_-_144994840 0.26 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr20_+_42086525 0.25 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr7_-_26904317 0.25 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr19_-_36545128 0.22 ENST00000538849.1
THAP8
THAP domain containing 8
chr9_+_131133598 0.18 ENST00000372853.4
ENST00000452446.1
ENST00000372850.1
ENST00000372847.1
URM1
ubiquitin related modifier 1
chr13_+_98086445 0.18 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr1_-_42384343 0.16 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr15_+_44580955 0.15 ENST00000345795.2
ENST00000360824.3
CASC4
cancer susceptibility candidate 4
chr9_-_14308004 0.14 ENST00000493697.1
NFIB
nuclear factor I/B
chr12_+_104458235 0.14 ENST00000229330.4
HCFC2
host cell factor C2
chr2_-_88427568 0.14 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr8_+_23430157 0.12 ENST00000399967.3
FP15737
FP15737
chr17_-_29648761 0.12 ENST00000247270.3
ENST00000462804.2
EVI2A
ecotropic viral integration site 2A
chr16_-_30582888 0.12 ENST00000563707.1
ENST00000567855.1
ZNF688
zinc finger protein 688
chr11_-_17498348 0.11 ENST00000389817.3
ENST00000302539.4
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr1_-_226374373 0.11 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr6_-_30524951 0.11 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr12_-_76478446 0.10 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr14_-_53619816 0.10 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1
DDHD domain containing 1
chr12_-_76478417 0.10 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr12_-_76478386 0.09 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr19_-_59084922 0.09 ENST00000215057.2
ENST00000599369.1
MZF1
myeloid zinc finger 1
chr14_-_59950724 0.08 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr2_-_27603582 0.07 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr19_-_59084647 0.06 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr22_-_43355858 0.05 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr11_+_101918153 0.05 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chrX_+_48367338 0.04 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN
porcupine homolog (Drosophila)
chr3_+_30647994 0.03 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr10_+_60028818 0.03 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr9_+_96338647 0.02 ENST00000359246.4
PHF2
PHD finger protein 2
chr7_-_105029812 0.02 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr16_-_70285797 0.01 ENST00000435634.1
EXOSC6
exosome component 6
chr16_-_46797149 0.01 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr3_+_30648066 0.00 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.5 GO:0060435 bronchiole development(GO:0060435)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.9 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway