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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HES1

Z-value: 0.87

Motif logo

Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
ENSG00000114315.3 HES1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_1938539440.581.4e-01Click!

Activity profile of HES1 motif

Sorted Z-values of HES1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_68269971 1.47 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr18_+_33877654 1.39 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr10_-_123357598 1.24 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
FGFR2
fibroblast growth factor receptor 2
chr8_+_95653373 1.15 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653427 1.14 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653302 1.14 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr1_-_9189229 1.10 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr10_-_123357910 0.95 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
FGFR2
fibroblast growth factor receptor 2
chr14_-_105635090 0.88 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr20_+_58152524 0.87 ENST00000359926.3
PHACTR3
phosphatase and actin regulator 3
chr17_+_78075361 0.76 ENST00000577106.1
ENST00000390015.3
GAA
glucosidase, alpha; acid
chr7_-_98030360 0.70 ENST00000005260.8
BAIAP2L1
BAI1-associated protein 2-like 1
chr17_-_3599696 0.69 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr19_+_38755203 0.69 ENST00000587090.1
ENST00000454580.3
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755042 0.68 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr8_+_124194752 0.67 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr15_+_41136216 0.67 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr1_-_205290865 0.66 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr7_-_44365020 0.63 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr17_-_42402138 0.62 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
SLC25A39
solute carrier family 25, member 39
chr17_-_3599327 0.62 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_+_44401479 0.61 ENST00000438616.3
ARTN
artemin
chr17_+_78075498 0.61 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr17_-_3599492 0.61 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr12_-_53614155 0.60 ENST00000543726.1
RARG
retinoic acid receptor, gamma
chr7_-_44365216 0.60 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr8_+_28351707 0.60 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr12_-_53614043 0.60 ENST00000338561.5
RARG
retinoic acid receptor, gamma
chr20_+_6748311 0.58 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr19_+_34287174 0.56 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr9_+_133971863 0.54 ENST00000372309.3
AIF1L
allograft inflammatory factor 1-like
chr2_-_73511559 0.53 ENST00000521871.1
FBXO41
F-box protein 41
chr9_+_133971909 0.52 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L
allograft inflammatory factor 1-like
chr11_+_124932955 0.50 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr9_-_139948487 0.49 ENST00000355097.2
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr1_-_231175964 0.49 ENST00000366654.4
FAM89A
family with sequence similarity 89, member A
chr15_+_89182178 0.49 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_+_18059906 0.49 ENST00000304101.4
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr1_-_19283163 0.48 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr11_+_124932986 0.47 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr8_-_142011036 0.46 ENST00000520892.1
PTK2
protein tyrosine kinase 2
chr5_+_140220769 0.46 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr11_+_124933191 0.46 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr1_-_175162048 0.45 ENST00000444639.1
KIAA0040
KIAA0040
chr2_+_106361333 0.44 ENST00000233154.4
ENST00000451463.2
NCK2
NCK adaptor protein 2
chrX_+_105969893 0.44 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr17_+_54671047 0.43 ENST00000332822.4
NOG
noggin
chr14_-_100070363 0.43 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr15_+_89181974 0.43 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr9_-_126030817 0.43 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP
spermatid perinuclear RNA binding protein
chr20_+_35201857 0.42 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr18_+_11752040 0.42 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr8_-_66754172 0.41 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr15_+_89182156 0.41 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_-_4401258 0.40 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr16_-_402639 0.39 ENST00000262320.3
AXIN1
axin 1
chr5_+_149737202 0.39 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr1_-_25291475 0.39 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr2_-_96811170 0.38 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr1_-_167522982 0.38 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr12_+_122064673 0.38 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr8_+_32406179 0.38 ENST00000405005.3
NRG1
neuregulin 1
chr16_-_4401284 0.37 ENST00000318059.3
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr14_+_67999999 0.36 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr20_+_61273797 0.36 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr20_+_35201993 0.36 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr1_+_152881014 0.36 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr8_+_104513086 0.36 ENST00000406091.3
RIMS2
regulating synaptic membrane exocytosis 2
chr15_-_63674034 0.36 ENST00000344366.3
ENST00000422263.2
CA12
carbonic anhydrase XII
chr16_-_4466565 0.35 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr19_-_46272106 0.35 ENST00000560168.1
SIX5
SIX homeobox 5
chr16_+_577697 0.35 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr14_-_91526462 0.35 ENST00000536315.2
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr2_+_64681641 0.34 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr8_+_145734433 0.34 ENST00000301327.4
MFSD3
major facilitator superfamily domain containing 3
chr21_-_42219065 0.34 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chrX_+_152907913 0.34 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr2_+_97426631 0.33 ENST00000377075.2
CNNM4
cyclin M4
chr6_+_43738444 0.33 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr1_-_117210290 0.32 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr8_-_28243590 0.32 ENST00000523095.1
ENST00000522795.1
ZNF395
zinc finger protein 395
chr8_-_145515055 0.32 ENST00000526552.1
ENST00000529231.1
ENST00000307404.5
BOP1
block of proliferation 1
chr20_-_50384864 0.31 ENST00000311637.5
ENST00000402822.1
ATP9A
ATPase, class II, type 9A
chr11_+_68080077 0.31 ENST00000294304.7
LRP5
low density lipoprotein receptor-related protein 5
chr1_-_32801825 0.31 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr16_+_2205755 0.31 ENST00000326181.6
TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr15_-_63674218 0.30 ENST00000178638.3
CA12
carbonic anhydrase XII
chr17_+_29718642 0.30 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr2_+_203499901 0.30 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr10_-_105615164 0.30 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr8_+_31496809 0.30 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr10_+_71561630 0.29 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr9_-_124976185 0.29 ENST00000464484.2
LHX6
LIM homeobox 6
chr14_-_91526922 0.29 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr10_+_71561649 0.29 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr7_-_140340576 0.29 ENST00000275884.6
ENST00000475837.1
DENND2A
DENN/MADD domain containing 2A
chr18_-_74207146 0.29 ENST00000443185.2
ZNF516
zinc finger protein 516
chr15_+_74908147 0.28 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CLK3
CDC-like kinase 3
chr7_-_139876812 0.28 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr6_-_19804973 0.28 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr1_+_227127981 0.28 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3
aarF domain containing kinase 3
chr15_-_67813924 0.28 ENST00000559298.1
IQCH-AS1
IQCH antisense RNA 1
chrX_-_7066159 0.27 ENST00000486446.2
ENST00000412827.2
ENST00000424830.2
ENST00000381077.5
ENST00000540122.1
HDHD1
haloacid dehalogenase-like hydrolase domain containing 1
chr8_-_28243934 0.27 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr11_+_64058820 0.26 ENST00000422670.2
KCNK4
potassium channel, subfamily K, member 4
chr6_-_143771799 0.26 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr7_-_994302 0.26 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr14_-_81687575 0.26 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_217262969 0.25 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr11_+_64058758 0.25 ENST00000538767.1
KCNK4
potassium channel, subfamily K, member 4
chr2_-_101925055 0.25 ENST00000295317.3
RNF149
ring finger protein 149
chr17_+_30813576 0.25 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr21_+_45527171 0.25 ENST00000291576.7
ENST00000456705.1
PWP2
PWP2 periodic tryptophan protein homolog (yeast)
chr13_-_44735393 0.25 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr15_+_42120283 0.25 ENST00000542534.2
ENST00000397299.4
ENST00000408047.1
ENST00000431823.1
ENST00000382448.4
ENST00000342159.4
PLA2G4B
JMJD7
JMJD7-PLA2G4B
phospholipase A2, group IVB (cytosolic)
jumonji domain containing 7
JMJD7-PLA2G4B readthrough
chr21_+_46359907 0.24 ENST00000291634.6
ENST00000397826.3
ENST00000458015.1
FAM207A
family with sequence similarity 207, member A
chr1_+_44445549 0.24 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr10_-_135379132 0.24 ENST00000343131.5
SYCE1
synaptonemal complex central element protein 1
chr10_+_134210672 0.24 ENST00000305233.5
ENST00000368609.4
PWWP2B
PWWP domain containing 2B
chr3_-_185542817 0.24 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_85514120 0.24 ENST00000370589.2
ENST00000341115.4
ENST00000370587.1
MCOLN3
mucolipin 3
chr3_+_184081175 0.24 ENST00000452961.1
ENST00000296223.3
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr1_-_38273840 0.24 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr19_+_797443 0.24 ENST00000394601.4
ENST00000589575.1
PTBP1
polypyrimidine tract binding protein 1
chr19_+_8274204 0.23 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
CERS4
ceramide synthase 4
chr8_-_102218292 0.23 ENST00000518336.1
ENST00000520454.1
ZNF706
zinc finger protein 706
chr9_-_124976154 0.23 ENST00000482062.1
LHX6
LIM homeobox 6
chr3_+_184081213 0.23 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr3_-_138763734 0.23 ENST00000413199.1
ENST00000502927.2
PRR23C
proline rich 23C
chr1_-_217262933 0.23 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr11_+_46354455 0.23 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr8_+_145515263 0.23 ENST00000528838.1
HSF1
heat shock transcription factor 1
chr10_-_99094458 0.23 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr19_+_8274185 0.23 ENST00000558268.1
ENST00000558331.1
CERS4
ceramide synthase 4
chr14_-_93582214 0.22 ENST00000556603.2
ENST00000354313.3
ITPK1
inositol-tetrakisphosphate 1-kinase
chr7_+_24613034 0.22 ENST00000409761.1
ENST00000396475.2
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr6_+_43739697 0.22 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr3_-_185542761 0.22 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr3_+_121554046 0.22 ENST00000273668.2
ENST00000451944.2
EAF2
ELL associated factor 2
chr10_+_74033672 0.22 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr19_-_3478477 0.22 ENST00000591708.1
C19orf77
chromosome 19 open reading frame 77
chr20_-_50385138 0.22 ENST00000338821.5
ATP9A
ATPase, class II, type 9A
chr3_+_51428704 0.22 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr12_+_122064398 0.22 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr22_+_38302285 0.22 ENST00000215957.6
MICALL1
MICAL-like 1
chr19_-_42724261 0.22 ENST00000595337.1
DEDD2
death effector domain containing 2
chr6_-_105850937 0.21 ENST00000369110.3
PREP
prolyl endopeptidase
chr19_-_14629224 0.21 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr7_-_558876 0.21 ENST00000354513.5
ENST00000402802.3
PDGFA
platelet-derived growth factor alpha polypeptide
chr9_-_139137648 0.21 ENST00000358701.5
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr22_+_29279552 0.21 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr5_-_78809950 0.21 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr14_-_77279153 0.21 ENST00000251089.2
ANGEL1
angel homolog 1 (Drosophila)
chr19_+_5823813 0.21 ENST00000303212.2
NRTN
neurturin
chr2_-_46769694 0.21 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr2_-_73053126 0.20 ENST00000272427.6
ENST00000410104.1
EXOC6B
exocyst complex component 6B
chr17_+_7348658 0.20 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr18_-_77793891 0.20 ENST00000592957.1
ENST00000585474.1
TXNL4A
thioredoxin-like 4A
chr1_+_44444865 0.20 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr9_+_101867359 0.20 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr12_+_53574464 0.20 ENST00000416904.3
ZNF740
zinc finger protein 740
chr22_+_46731596 0.20 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr1_-_46152174 0.20 ENST00000290795.3
ENST00000355105.3
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr1_-_200379129 0.20 ENST00000367353.1
ZNF281
zinc finger protein 281
chr18_-_33077556 0.20 ENST00000589273.1
ENST00000586489.1
INO80C
INO80 complex subunit C
chr17_+_73257945 0.19 ENST00000579002.1
MRPS7
mitochondrial ribosomal protein S7
chr14_-_93581615 0.19 ENST00000555553.1
ENST00000555495.1
ENST00000554999.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chr16_-_2059797 0.19 ENST00000563630.1
ZNF598
zinc finger protein 598
chr20_-_43280325 0.19 ENST00000537820.1
ADA
adenosine deaminase
chr11_-_113746212 0.19 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28
ubiquitin specific peptidase 28
chr2_+_26915584 0.19 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr19_+_38397839 0.19 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr3_+_184081137 0.19 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr16_+_66914264 0.19 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr16_-_4466622 0.19 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
CORO7
coronin 7
chr9_-_140484917 0.19 ENST00000298585.2
ZMYND19
zinc finger, MYND-type containing 19
chr2_+_27237615 0.19 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr1_+_41707996 0.19 ENST00000425554.1
RP11-399E6.1
RP11-399E6.1
chr12_-_124018252 0.19 ENST00000376874.4
RILPL1
Rab interacting lysosomal protein-like 1
chr6_+_89855765 0.19 ENST00000275072.4
PM20D2
peptidase M20 domain containing 2
chr2_-_25142708 0.18 ENST00000260600.5
ENST00000435135.1
ADCY3
adenylate cyclase 3
chr1_-_200379180 0.18 ENST00000294740.3
ZNF281
zinc finger protein 281
chr17_-_2614927 0.18 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr9_+_101867387 0.18 ENST00000374990.2
ENST00000552516.1
TGFBR1
transforming growth factor, beta receptor 1
chrX_+_21392529 0.18 ENST00000425654.2
ENST00000543067.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr17_+_7348374 0.18 ENST00000306071.2
ENST00000572857.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr5_+_612387 0.18 ENST00000264935.5
ENST00000444221.1
CEP72
centrosomal protein 72kDa
chr19_-_19051927 0.18 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr6_-_13711773 0.18 ENST00000011619.3
RANBP9
RAN binding protein 9
chr14_-_51562745 0.17 ENST00000298355.3
TRIM9
tripartite motif containing 9
chr11_-_113746277 0.17 ENST00000003302.4
ENST00000545540.1
USP28
ubiquitin specific peptidase 28
chr3_+_10857885 0.17 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr4_+_144257915 0.17 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr8_+_25042192 0.17 ENST00000410074.1
DOCK5
dedicator of cytokinesis 5
chr14_-_93582148 0.17 ENST00000267615.6
ENST00000553452.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chr5_+_44809027 0.17 ENST00000507110.1
MRPS30
mitochondrial ribosomal protein S30
chr19_+_984313 0.17 ENST00000251289.5
ENST00000587001.2
ENST00000607440.1
WDR18
WD repeat domain 18
chr14_+_104604916 0.17 ENST00000423312.2
KIF26A
kinesin family member 26A
chr14_-_24780573 0.17 ENST00000336557.5
ENST00000258807.5
CIDEB
cell death-inducing DFFA-like effector b
chr3_-_179169181 0.17 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.3 1.4 GO:0002086 diaphragm contraction(GO:0002086)
0.3 1.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.6 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 0.6 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.2 0.6 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.4 GO:0048320 axial mesoderm formation(GO:0048320) canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 1.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.6 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.3 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.5 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.9 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.4 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.2 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.4 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 1.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.3 GO:0046102 inosine metabolic process(GO:0046102)
0.1 0.2 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.2 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355)
0.1 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 1.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.7 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 1.5 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.8 GO:0032780 protein import into mitochondrial matrix(GO:0030150) negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 3.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.0 GO:0048541 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0045820 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) lung vasculature development(GO:0060426) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 2.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 1.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 1.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.4 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 0.6 GO:0052831 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.2 1.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.5 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0070025 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.3 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 5.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.0 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import