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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HIC2

Z-value: 0.78

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Transcription factors associated with HIC2

Gene Symbol Gene ID Gene Info
HIC2
ENSG00000169635.5 HIC2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIC2hg19_v2_chr22_+_21771656_217716930.285.0e-01Click!

Activity profile of HIC2 motif

Sorted Z-values of HIC2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_51522955 1.26 ENST00000358789.3
 KLK10
 kallikrein-related peptidase 10
chr12_-_52845910 1.22 ENST00000252252.3
 KRT6B
 keratin 6B
chr5_+_167181917 1.06 ENST00000519204.1
 TENM2
 teneurin transmembrane protein 2
chr14_-_94856987 0.96 ENST00000449399.3
ENST00000404814.4
 SERPINA1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_+_124194875 0.94 ENST00000522648.1
ENST00000276699.6
 FAM83A
 family with sequence similarity 83, member A
chr1_+_109792641 0.86 ENST00000271332.3
 CELSR2
 cadherin, EGF LAG seven-pass G-type receptor 2
chr2_-_70781087 0.82 ENST00000394241.3
ENST00000295400.6
 TGFA
 transforming growth factor, alpha
chr17_+_54671047 0.81 ENST00000332822.4
 NOG
 noggin
chr8_-_75233563 0.80 ENST00000342232.4
 JPH1
 junctophilin 1
chr1_-_153363452 0.80 ENST00000368732.1
ENST00000368733.3
 S100A8
 S100 calcium binding protein A8
chr2_+_95940186 0.77 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
 PROM2
 prominin 2
chr17_+_73717551 0.75 ENST00000450894.3
 ITGB4
 integrin, beta 4
chr14_+_96671016 0.74 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
 BDKRB2
RP11-404P21.8
 bradykinin receptor B2
Uncharacterized protein
chr12_-_52828147 0.74 ENST00000252245.5
 KRT75
 keratin 75
chr12_+_41086297 0.74 ENST00000551295.2
 CNTN1
 contactin 1
chr19_+_751122 0.72 ENST00000215582.6
 MISP
 mitotic spindle positioning
chr14_-_94856951 0.70 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
 SERPINA1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr18_+_21452964 0.69 ENST00000587184.1
 LAMA3
 laminin, alpha 3
chr2_+_69001913 0.68 ENST00000409030.3
ENST00000409220.1
 ARHGAP25
 Rho GTPase activating protein 25
chr2_-_235405168 0.68 ENST00000339728.3
 ARL4C
 ADP-ribosylation factor-like 4C
chr17_+_73717407 0.67 ENST00000579662.1
 ITGB4
 integrin, beta 4
chr1_+_205473720 0.65 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
 CDK18
 cyclin-dependent kinase 18
chr19_-_10697895 0.62 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
 AP1M2
 adaptor-related protein complex 1, mu 2 subunit
chr22_-_20255212 0.61 ENST00000416372.1
 RTN4R
 reticulon 4 receptor
chr15_+_40532058 0.60 ENST00000260404.4
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr2_-_70780770 0.58 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA
 transforming growth factor, alpha
chr15_+_90728145 0.56 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
 SEMA4B
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr8_+_124194752 0.56 ENST00000318462.6
 FAM83A
 family with sequence similarity 83, member A
chr9_-_23821842 0.56 ENST00000544538.1
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr17_-_39928106 0.55 ENST00000540235.1
 JUP
 junction plakoglobin
chr3_-_12800751 0.54 ENST00000435218.2
ENST00000435575.1
 TMEM40
 transmembrane protein 40
chr17_+_73717516 0.54 ENST00000200181.3
ENST00000339591.3
 ITGB4
 integrin, beta 4
chr9_+_132099158 0.53 ENST00000444125.1
 RP11-65J3.1
 RP11-65J3.1
chr12_-_28125638 0.53 ENST00000545234.1
 PTHLH
 parathyroid hormone-like hormone
chr14_-_94857004 0.52 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
 SERPINA1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_209825674 0.51 ENST00000367030.3
ENST00000356082.4
 LAMB3
 laminin, beta 3
chrX_+_68048803 0.51 ENST00000204961.4
 EFNB1
 ephrin-B1
chr3_+_189349162 0.51 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
 TP63
 tumor protein p63
chr8_-_125740730 0.51 ENST00000354184.4
 MTSS1
 metastasis suppressor 1
chr19_-_51487282 0.50 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
 KLK7
 kallikrein-related peptidase 7
chr19_-_39264072 0.48 ENST00000599035.1
ENST00000378626.4
 LGALS7
 lectin, galactoside-binding, soluble, 7
chr2_-_46385 0.47 ENST00000327669.4
 FAM110C
 family with sequence similarity 110, member C
chr8_-_57232656 0.46 ENST00000396721.2
 SDR16C5
 short chain dehydrogenase/reductase family 16C, member 5
chr1_+_32042131 0.45 ENST00000271064.7
ENST00000537531.1
 TINAGL1
 tubulointerstitial nephritis antigen-like 1
chr8_-_125740514 0.45 ENST00000325064.5
ENST00000518547.1
 MTSS1
 metastasis suppressor 1
chr9_-_23821273 0.45 ENST00000380110.4
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr1_+_44399466 0.44 ENST00000498139.2
ENST00000491846.1
 ARTN
 artemin
chr12_-_56882136 0.44 ENST00000311966.4
 GLS2
 glutaminase 2 (liver, mitochondrial)
chr19_-_51523412 0.44 ENST00000391805.1
ENST00000599077.1
 KLK10
 kallikrein-related peptidase 10
chrX_-_153151586 0.44 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
 L1CAM
 L1 cell adhesion molecule
chr1_+_32042105 0.44 ENST00000457433.2
ENST00000441210.2
 TINAGL1
 tubulointerstitial nephritis antigen-like 1
chr12_-_52911718 0.43 ENST00000548409.1
 KRT5
 keratin 5
chr15_+_40531243 0.43 ENST00000558055.1
ENST00000455577.2
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_44398943 0.43 ENST00000372359.5
ENST00000414809.3
 ARTN
 artemin
chr11_-_118023490 0.43 ENST00000324727.4
 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
chr12_-_52685312 0.42 ENST00000327741.5
 KRT81
 keratin 81
chr12_+_83080659 0.42 ENST00000321196.3
 TMTC2
 transmembrane and tetratricopeptide repeat containing 2
chr8_+_82644669 0.42 ENST00000297265.4
 CHMP4C
 charged multivesicular body protein 4C
chr6_+_150464155 0.42 ENST00000361131.4
 PPP1R14C
 protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr10_+_5566916 0.41 ENST00000315238.1
 CALML3
 calmodulin-like 3
chr18_-_47376197 0.40 ENST00000592688.1
 MYO5B
 myosin VB
chr17_-_34122596 0.40 ENST00000250144.8
 MMP28
 matrix metallopeptidase 28
chr6_+_43739697 0.40 ENST00000230480.6
 VEGFA
 vascular endothelial growth factor A
chr19_-_51523275 0.39 ENST00000309958.3
 KLK10
 kallikrein-related peptidase 10
chr5_+_131409476 0.39 ENST00000296871.2
 CSF2
 colony stimulating factor 2 (granulocyte-macrophage)
chr1_+_33231268 0.39 ENST00000373480.1
 KIAA1522
 KIAA1522
chr19_+_7710774 0.39 ENST00000602355.1
 STXBP2
 syntaxin binding protein 2
chr11_-_118134997 0.38 ENST00000278937.2
 MPZL2
 myelin protein zero-like 2
chr7_-_44265492 0.38 ENST00000425809.1
 CAMK2B
 calcium/calmodulin-dependent protein kinase II beta
chr2_+_219187871 0.38 ENST00000258362.3
 PNKD
 paroxysmal nonkinesigenic dyskinesia
chr1_+_15250596 0.38 ENST00000361144.5
 KAZN
 kazrin, periplakin interacting protein
chr10_-_123274693 0.38 ENST00000429361.1
 FGFR2
 fibroblast growth factor receptor 2
chr1_+_65613340 0.38 ENST00000546702.1
 AK4
 adenylate kinase 4
chr17_-_3595181 0.38 ENST00000552050.1
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr15_-_83621435 0.38 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
 HOMER2
 homer homolog 2 (Drosophila)
chr12_-_53320245 0.38 ENST00000552150.1
 KRT8
 keratin 8
chr6_-_41130841 0.37 ENST00000373122.4
 TREM2
 triggering receptor expressed on myeloid cells 2
chr1_+_26869597 0.36 ENST00000530003.1
 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_38657849 0.36 ENST00000254051.6
 TNS4
 tensin 4
chr12_-_31479045 0.36 ENST00000539409.1
ENST00000395766.1
 FAM60A
 family with sequence similarity 60, member A
chr11_-_119991589 0.36 ENST00000526881.1
 TRIM29
 tripartite motif containing 29
chr2_+_173292280 0.35 ENST00000264107.7
 ITGA6
 integrin, alpha 6
chr1_+_233765353 0.35 ENST00000366620.1
 KCNK1
 potassium channel, subfamily K, member 1
chr2_+_173292301 0.35 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
 ITGA6
 integrin, alpha 6
chrX_-_153141302 0.35 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
 L1CAM
 L1 cell adhesion molecule
chr1_-_231175964 0.35 ENST00000366654.4
 FAM89A
 family with sequence similarity 89, member A
chr11_+_10471836 0.34 ENST00000444303.2
 AMPD3
 adenosine monophosphate deaminase 3
chr2_-_238499303 0.34 ENST00000409576.1
 RAB17
 RAB17, member RAS oncogene family
chr17_-_8021710 0.34 ENST00000380149.1
ENST00000448843.2
 ALOXE3
 arachidonate lipoxygenase 3
chr2_+_95940220 0.34 ENST00000542147.1
 PROM2
 prominin 2
chr1_-_147245484 0.34 ENST00000271348.2
 GJA5
 gap junction protein, alpha 5, 40kDa
chr2_-_238499337 0.34 ENST00000411462.1
ENST00000409822.1
 RAB17
 RAB17, member RAS oncogene family
chr3_-_69435428 0.33 ENST00000542259.1
 FRMD4B
 FERM domain containing 4B
chr19_-_51487071 0.33 ENST00000391807.1
ENST00000593904.1
 KLK7
 kallikrein-related peptidase 7
chr1_+_40420802 0.33 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
 MFSD2A
 major facilitator superfamily domain containing 2A
chr8_+_21915368 0.33 ENST00000265800.5
ENST00000517418.1
 DMTN
 dematin actin binding protein
chr2_+_85360499 0.33 ENST00000282111.3
 TCF7L1
 transcription factor 7-like 1 (T-cell specific, HMG-box)
chr3_-_69435224 0.32 ENST00000398540.3
 FRMD4B
 FERM domain containing 4B
chr14_+_61995722 0.32 ENST00000556347.1
 RP11-47I22.4
 RP11-47I22.4
chr1_-_217262969 0.32 ENST00000361525.3
 ESRRG
 estrogen-related receptor gamma
chr11_+_111411384 0.32 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
 LAYN
 layilin
chr7_+_147830776 0.32 ENST00000538075.1
 CNTNAP2
 contactin associated protein-like 2
chr8_+_120220561 0.32 ENST00000276681.6
 MAL2
 mal, T-cell differentiation protein 2 (gene/pseudogene)
chr16_+_30934376 0.32 ENST00000562798.1
ENST00000471231.2
 FBXL19
 F-box and leucine-rich repeat protein 19
chr22_+_33197683 0.31 ENST00000266085.6
 TIMP3
 TIMP metallopeptidase inhibitor 3
chr2_+_173292390 0.31 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
 ITGA6
 integrin, alpha 6
chr17_+_7942335 0.31 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
 ALOX15B
 arachidonate 15-lipoxygenase, type B
chr22_+_25960786 0.30 ENST00000324198.6
 ADRBK2
 adrenergic, beta, receptor kinase 2
chr1_-_156675368 0.30 ENST00000368222.3
 CRABP2
 cellular retinoic acid binding protein 2
chr2_+_220492373 0.30 ENST00000317151.3
 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
chr6_-_30712313 0.30 ENST00000376377.2
ENST00000259874.5
 IER3
 immediate early response 3
chr20_+_61299155 0.30 ENST00000451793.1
 SLCO4A1
 solute carrier organic anion transporter family, member 4A1
chr15_+_80987617 0.30 ENST00000258884.4
ENST00000558464.1
 ABHD17C
 abhydrolase domain containing 17C
chr1_+_152881014 0.30 ENST00000368764.3
ENST00000392667.2
 IVL
 involucrin
chr7_+_128784712 0.29 ENST00000289407.4
 TSPAN33
 tetraspanin 33
chr11_-_119993734 0.29 ENST00000533302.1
 TRIM29
 tripartite motif containing 29
chr11_-_72492903 0.29 ENST00000537947.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr16_-_87903079 0.29 ENST00000261622.4
 SLC7A5
 solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr6_-_41130914 0.29 ENST00000373113.3
ENST00000338469.3
 TREM2
 triggering receptor expressed on myeloid cells 2
chr11_-_119599794 0.28 ENST00000264025.3
 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr17_-_7166500 0.28 ENST00000575313.1
ENST00000397317.4
 CLDN7
 claudin 7
chr5_-_139726181 0.28 ENST00000507104.1
ENST00000230990.6
 HBEGF
 heparin-binding EGF-like growth factor
chr10_-_76995769 0.28 ENST00000372538.3
 COMTD1
 catechol-O-methyltransferase domain containing 1
chr10_-_76995675 0.28 ENST00000469299.1
 COMTD1
 catechol-O-methyltransferase domain containing 1
chr1_-_9189229 0.28 ENST00000377411.4
 GPR157
 G protein-coupled receptor 157
chr4_-_84255935 0.28 ENST00000513463.1
 HPSE
 heparanase
chr1_+_152691998 0.28 ENST00000368775.2
 C1orf68
 chromosome 1 open reading frame 68
chr11_+_1856034 0.28 ENST00000341958.3
 SYT8
 synaptotagmin VIII
chr6_+_30850697 0.28 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr1_-_217262933 0.28 ENST00000359162.2
 ESRRG
 estrogen-related receptor gamma
chr4_-_84256024 0.28 ENST00000311412.5
 HPSE
 heparanase
chr17_-_7164410 0.28 ENST00000574070.1
 CLDN7
 claudin 7
chr6_+_13925318 0.27 ENST00000423553.2
ENST00000537388.1
 RNF182
 ring finger protein 182
chr1_-_38273840 0.27 ENST00000373044.2
 YRDC
 yrdC N(6)-threonylcarbamoyltransferase domain containing
chr20_+_61287711 0.27 ENST00000370507.1
 SLCO4A1
 solute carrier organic anion transporter family, member 4A1
chr15_-_44486632 0.27 ENST00000484674.1
 FRMD5
 FERM domain containing 5
chr1_-_156786634 0.27 ENST00000392306.2
ENST00000368199.3
 SH2D2A
 SH2 domain containing 2A
chr2_+_220492287 0.27 ENST00000273063.6
ENST00000373762.3
 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
chr16_+_57406368 0.26 ENST00000006053.6
ENST00000563383.1
 CX3CL1
 chemokine (C-X3-C motif) ligand 1
chr2_-_235405679 0.26 ENST00000390645.2
 ARL4C
 ADP-ribosylation factor-like 4C
chr1_-_156786530 0.26 ENST00000368198.3
 SH2D2A
 SH2 domain containing 2A
chr7_-_16840820 0.26 ENST00000450569.1
 AGR2
 anterior gradient 2
chr2_-_31360887 0.26 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
 GALNT14
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr10_-_116286656 0.26 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
 ABLIM1
 actin binding LIM protein 1
chr11_-_72492878 0.26 ENST00000535054.1
ENST00000545082.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr19_+_41281060 0.26 ENST00000594436.1
ENST00000597784.1
 MIA
 melanoma inhibitory activity
chr1_+_156119466 0.26 ENST00000414683.1
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_24646002 0.26 ENST00000356046.2
 GRHL3
 grainyhead-like 3 (Drosophila)
chr14_-_51411194 0.26 ENST00000544180.2
 PYGL
 phosphorylase, glycogen, liver
chr9_-_124989804 0.26 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr12_-_31479107 0.26 ENST00000542983.1
 FAM60A
 family with sequence similarity 60, member A
chr5_+_66300446 0.25 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr15_+_90319557 0.25 ENST00000341735.3
 MESP2
 mesoderm posterior 2 homolog (mouse)
chr11_+_10472223 0.25 ENST00000396554.3
ENST00000524866.1
 AMPD3
 adenosine monophosphate deaminase 3
chr14_-_75422280 0.25 ENST00000238607.6
ENST00000553716.1
 PGF
 placental growth factor
chr2_+_113875466 0.25 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
 IL1RN
 interleukin 1 receptor antagonist
chr6_-_55443958 0.25 ENST00000370850.2
 HMGCLL1
 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr8_+_24771265 0.25 ENST00000518131.1
ENST00000437366.2
 NEFM
 neurofilament, medium polypeptide
chr5_-_141249154 0.25 ENST00000357517.5
ENST00000536585.1
 PCDH1
 protocadherin 1
chr3_+_10857885 0.25 ENST00000254488.2
ENST00000454147.1
 SLC6A11
 solute carrier family 6 (neurotransmitter transporter), member 11
chr5_-_134914673 0.24 ENST00000512158.1
 CXCL14
 chemokine (C-X-C motif) ligand 14
chr1_+_156119798 0.24 ENST00000355014.2
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr11_-_44972390 0.24 ENST00000395648.3
ENST00000531928.2
 TP53I11
 tumor protein p53 inducible protein 11
chr1_+_65613217 0.24 ENST00000545314.1
 AK4
 adenylate kinase 4
chr8_+_21911054 0.24 ENST00000519850.1
ENST00000381470.3
 DMTN
 dematin actin binding protein
chr7_-_134896234 0.24 ENST00000354475.4
ENST00000344400.5
 WDR91
 WD repeat domain 91
chr2_+_113931513 0.24 ENST00000245796.6
ENST00000441564.3
 PSD4
 pleckstrin and Sec7 domain containing 4
chr12_-_6483969 0.24 ENST00000396966.2
 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
chr14_-_23623577 0.24 ENST00000422941.2
ENST00000453702.1
 SLC7A8
 solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr2_-_31361543 0.24 ENST00000349752.5
 GALNT14
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_+_220960033 0.24 ENST00000366910.5
 MARC1
 mitochondrial amidoxime reducing component 1
chr18_+_11752040 0.24 ENST00000423027.3
 GNAL
 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr17_-_39580775 0.24 ENST00000225550.3
 KRT37
 keratin 37
chr2_-_238499131 0.24 ENST00000538644.1
 RAB17
 RAB17, member RAS oncogene family
chr10_-_103880209 0.24 ENST00000425280.1
 LDB1
 LIM domain binding 1
chr19_-_44174305 0.23 ENST00000601723.1
ENST00000339082.3
 PLAUR
 plasminogen activator, urokinase receptor
chr11_-_72496976 0.23 ENST00000539138.1
ENST00000542989.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr19_-_44174330 0.23 ENST00000340093.3
 PLAUR
 plasminogen activator, urokinase receptor
chr7_+_73245193 0.23 ENST00000340958.2
 CLDN4
 claudin 4
chr10_+_5454505 0.23 ENST00000355029.4
 NET1
 neuroepithelial cell transforming 1
chr9_-_112260531 0.23 ENST00000374541.2
ENST00000262539.3
 PTPN3
 protein tyrosine phosphatase, non-receptor type 3
chrX_-_24690771 0.23 ENST00000379145.1
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr17_-_4643114 0.23 ENST00000293778.6
 CXCL16
 chemokine (C-X-C motif) ligand 16
chr8_+_28351707 0.23 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
 FZD3
 frizzled family receptor 3
chr22_+_51112800 0.22 ENST00000414786.2
 SHANK3
 SH3 and multiple ankyrin repeat domains 3
chr18_+_12254318 0.22 ENST00000320477.9
 CIDEA
 cell death-inducing DFFA-like effector a
chr2_+_220325441 0.22 ENST00000396688.1
 SPEG
 SPEG complex locus
chr8_-_139926236 0.22 ENST00000303045.6
ENST00000435777.1
 COL22A1
 collagen, type XXII, alpha 1
chr3_+_184080387 0.22 ENST00000455712.1
 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
chr18_+_21269404 0.22 ENST00000313654.9
 LAMA3
 laminin, alpha 3
chr16_-_11681316 0.21 ENST00000571688.1
 LITAF
 lipopolysaccharide-induced TNF factor
chr9_-_127263265 0.21 ENST00000373587.3
 NR5A1
 nuclear receptor subfamily 5, group A, member 1
chr8_-_144655141 0.21 ENST00000398882.3
 MROH6
 maestro heat-like repeat family member 6
chr2_-_229046361 0.21 ENST00000392056.3
 SPHKAP
 SPHK1 interactor, AKAP domain containing
chr14_+_42076765 0.21 ENST00000298119.4
 LRFN5
 leucine rich repeat and fibronectin type III domain containing 5
chr11_+_128563652 0.21 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr5_+_176784837 0.21 ENST00000408923.3
 RGS14
 regulator of G-protein signaling 14
chr16_+_81812863 0.21 ENST00000359376.3
 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr4_+_3465027 0.21 ENST00000389653.2
ENST00000507039.1
ENST00000340083.5
 DOK7
 docking protein 7
chr12_-_6484376 0.20 ENST00000360168.3
ENST00000358945.3
 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 0.7 GO:0032499 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.2 3.1 GO:0035878 nail development(GO:0035878)
0.2 0.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.9 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 1.0 GO:0061312 BMP signaling pathway involved in heart development(GO:0061312)
0.2 1.0 GO:0030035 microspike assembly(GO:0030035)
0.2 0.9 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.5 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.1 0.4 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.1 0.4 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.8 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.3 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.8 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.3 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.3 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.2 GO:1904693 negative regulation of mitotic cell cycle, embryonic(GO:0045976) midbrain morphogenesis(GO:1904693)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.1 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 0.8 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.5 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.8 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.6 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 2.0 GO:0007398 ectoderm development(GO:0007398)
0.1 0.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.2 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.3 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.1 0.2 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.4 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.0 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.8 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0002884 negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0032899 regulation of neurotrophin production(GO:0032899)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.1 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.4 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.0 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:1901159 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 2.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.4 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.7 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.0 GO:0097695 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0046075 dTTP metabolic process(GO:0046075)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0046086 purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) adenosine biosynthetic process(GO:0046086)
0.0 0.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.4 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 2.4 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0 0.2 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.0 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0018013 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868) glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:2001250 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.8 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0046066 dGDP metabolic process(GO:0046066)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.3 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.0 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.1 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983) response to dithiothreitol(GO:0072720)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.5 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.2 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.0 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0048066 melanocyte differentiation(GO:0030318) developmental pigmentation(GO:0048066)
0.0 0.1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.0 GO:0071301 transcription factor catabolic process(GO:0036369) cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.0 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.0 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.0 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.0 GO:0032618 interleukin-15 production(GO:0032618)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.0 GO:0071231 cellular response to folic acid(GO:0071231)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.2 1.1 GO:0044393 microspike(GO:0044393)
0.2 1.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.1 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 3.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 3.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.7 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.5 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0010008 endosome membrane(GO:0010008)
0.0 0.0 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 3.0 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.6 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.5 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0030305 heparanase activity(GO:0030305)
0.1 0.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.4 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.3 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0038064 collagen receptor activity(GO:0038064)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.3 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0015141 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.0 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.7 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 4.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis