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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HNF1A_HNF1B

Z-value: 0.70

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
HNF1A
ENSG00000135100.13 HNF1A
HNF1B
ENSG00000108753.8 HNF1B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF1Ahg19_v2_chr12_+_121416489_1214165520.772.4e-02Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_65171315 0.81 ENST00000394691.1
 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_-_29013017 0.70 ENST00000377175.1
 OR2W1
 olfactory receptor, family 2, subfamily W, member 1
chr1_-_207206092 0.64 ENST00000359470.5
ENST00000461135.2
 C1orf116
 chromosome 1 open reading frame 116
chr14_-_94854926 0.58 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
 SERPINA1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_-_72649763 0.58 ENST00000513476.1
 GC
 group-specific component (vitamin D binding protein)
chrX_-_15683147 0.52 ENST00000380342.3
 TMEM27
 transmembrane protein 27
chr14_+_65171099 0.50 ENST00000247226.7
 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_-_110723194 0.46 ENST00000394635.3
 CFI
 complement factor I
chr4_-_110723335 0.46 ENST00000394634.2
 CFI
 complement factor I
chr4_-_110723134 0.46 ENST00000510800.1
ENST00000512148.1
 CFI
 complement factor I
chr22_+_45098067 0.45 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
 PRR5
PRR5-ARHGAP8
 proline rich 5 (renal)
PRR5-ARHGAP8 readthrough
chr4_+_74301880 0.44 ENST00000395792.2
ENST00000226359.2
 AFP
 alpha-fetoprotein
chr17_-_26733179 0.39 ENST00000440501.1
ENST00000321666.5
 SLC46A1
 solute carrier family 46 (folate transporter), member 1
chr4_-_155511887 0.37 ENST00000302053.3
ENST00000403106.3
 FGA
 fibrinogen alpha chain
chr19_-_36304201 0.37 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr10_+_99344071 0.35 ENST00000370647.4
ENST00000370646.4
 HOGA1
 4-hydroxy-2-oxoglutarate aldolase 1
chr17_-_64225508 0.34 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr6_+_7541845 0.33 ENST00000418664.2
 DSP
 desmoplakin
chr4_+_155484155 0.31 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr2_+_27719697 0.28 ENST00000264717.2
ENST00000424318.2
 GCKR
 glucokinase (hexokinase 4) regulator
chr5_+_176514413 0.27 ENST00000513166.1
 FGFR4
 fibroblast growth factor receptor 4
chr13_-_103719196 0.25 ENST00000245312.3
 SLC10A2
 solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr5_+_176513868 0.25 ENST00000292408.4
 FGFR4
 fibroblast growth factor receptor 4
chr12_+_70132632 0.25 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
 RAB3IP
 RAB3A interacting protein
chr8_+_21911054 0.24 ENST00000519850.1
ENST00000381470.3
 DMTN
 dematin actin binding protein
chr3_-_74570291 0.24 ENST00000263665.6
 CNTN3
 contactin 3 (plasmacytoma associated)
chr11_+_1860200 0.23 ENST00000381911.1
 TNNI2
 troponin I type 2 (skeletal, fast)
chr4_-_74486217 0.22 ENST00000335049.5
ENST00000307439.5
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr19_-_49565254 0.21 ENST00000593537.1
 NTF4
 neurotrophin 4
chr5_+_176513895 0.20 ENST00000503708.1
ENST00000393648.2
ENST00000514472.1
ENST00000502906.1
ENST00000292410.3
ENST00000510911.1
 FGFR4
 fibroblast growth factor receptor 4
chr16_-_57831914 0.20 ENST00000421376.2
 KIFC3
 kinesin family member C3
chr20_+_42984330 0.20 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
 HNF4A
 hepatocyte nuclear factor 4, alpha
chr8_-_87242589 0.20 ENST00000419776.2
ENST00000297524.3
 SLC7A13
 solute carrier family 7 (anionic amino acid transporter), member 13
chr5_-_35195338 0.19 ENST00000509839.1
 PRLR
 prolactin receptor
chr11_-_107729887 0.18 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr6_-_51952418 0.18 ENST00000371117.3
 PKHD1
 polycystic kidney and hepatic disease 1 (autosomal recessive)
chr17_+_1646130 0.17 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
 SERPINF2
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr16_+_20775358 0.17 ENST00000440284.2
 ACSM3
 acyl-CoA synthetase medium-chain family member 3
chr2_+_234668894 0.16 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
 UGT1A8
UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr14_+_39703112 0.16 ENST00000555143.1
ENST00000280082.3
 MIA2
 melanoma inhibitory activity 2
chr12_-_39837192 0.15 ENST00000361961.3
ENST00000395670.3
 KIF21A
 kinesin family member 21A
chr12_+_100867694 0.15 ENST00000392986.3
ENST00000549996.1
 NR1H4
 nuclear receptor subfamily 1, group H, member 4
chr4_-_22444733 0.15 ENST00000508133.1
 GPR125
 G protein-coupled receptor 125
chr19_+_6464502 0.15 ENST00000308243.7
 CRB3
 crumbs homolog 3 (Drosophila)
chr5_-_139726181 0.14 ENST00000507104.1
ENST00000230990.6
 HBEGF
 heparin-binding EGF-like growth factor
chr10_-_61495760 0.14 ENST00000395347.1
 SLC16A9
 solute carrier family 16, member 9
chr2_+_182850743 0.14 ENST00000409702.1
 PPP1R1C
 protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr19_+_6464243 0.14 ENST00000600229.1
ENST00000356762.3
 CRB3
 crumbs homolog 3 (Drosophila)
chr4_+_8201091 0.14 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
 SH3TC1
 SH3 domain and tetratricopeptide repeats 1
chr6_-_25874440 0.14 ENST00000361703.6
ENST00000397060.4
 SLC17A3
 solute carrier family 17 (organic anion transporter), member 3
chr1_-_20141763 0.14 ENST00000375121.2
 RNF186
 ring finger protein 186
chr19_-_43099070 0.13 ENST00000244336.5
 CEACAM8
 carcinoembryonic antigen-related cell adhesion molecule 8
chr1_-_67266939 0.13 ENST00000304526.2
 INSL5
 insulin-like 5
chr4_-_76944621 0.13 ENST00000306602.1
 CXCL10
 chemokine (C-X-C motif) ligand 10
chr20_+_35973080 0.13 ENST00000445403.1
 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr4_-_74486347 0.12 ENST00000342081.3
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr2_+_182850551 0.12 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
 PPP1R1C
 protein phosphatase 1, regulatory (inhibitor) subunit 1C
chrX_+_107288239 0.12 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr8_-_124749609 0.12 ENST00000262219.6
ENST00000419625.1
 ANXA13
 annexin A13
chr12_-_18243119 0.12 ENST00000538724.1
ENST00000229002.2
 RERGL
 RERG/RAS-like
chr6_-_30899924 0.12 ENST00000359086.3
 SFTA2
 surfactant associated 2
chr4_-_74486109 0.11 ENST00000395777.2
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr17_+_73642486 0.11 ENST00000579469.1
 SMIM6
 small integral membrane protein 6
chr17_+_73642315 0.11 ENST00000556126.2
 SMIM6
 small integral membrane protein 6
chr7_-_50633078 0.11 ENST00000444124.2
 DDC
 dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr16_-_69385681 0.11 ENST00000288025.3
 TMED6
 transmembrane emp24 protein transport domain containing 6
chrX_+_107288197 0.11 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr6_+_106534192 0.10 ENST00000369091.2
ENST00000369096.4
 PRDM1
 PR domain containing 1, with ZNF domain
chr16_+_21244986 0.10 ENST00000311620.5
 ANKS4B
 ankyrin repeat and sterile alpha motif domain containing 4B
chr16_-_55909211 0.09 ENST00000520435.1
 CES5A
 carboxylesterase 5A
chr6_-_52628271 0.09 ENST00000493422.1
 GSTA2
 glutathione S-transferase alpha 2
chr19_+_39138320 0.09 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
 ACTN4
 actinin, alpha 4
chr16_-_55909255 0.09 ENST00000290567.9
 CES5A
 carboxylesterase 5A
chr16_-_55909272 0.09 ENST00000319165.9
 CES5A
 carboxylesterase 5A
chr4_-_69434245 0.09 ENST00000317746.2
 UGT2B17
 UDP glucuronosyltransferase 2 family, polypeptide B17
chr14_-_94759361 0.09 ENST00000393096.1
 SERPINA10
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_-_44580861 0.09 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
 NPC1L1
 NPC1-like 1
chr14_-_94759408 0.09 ENST00000554723.1
 SERPINA10
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_55505184 0.09 ENST00000302118.5
 PCSK9
 proprotein convertase subtilisin/kexin type 9
chr2_+_234601512 0.09 ENST00000305139.6
 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
chr4_+_155484103 0.09 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr5_-_77844974 0.08 ENST00000515007.2
 LHFPL2
 lipoma HMGIC fusion partner-like 2
chr11_-_128894053 0.08 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr8_-_70745575 0.08 ENST00000524945.1
 SLCO5A1
 solute carrier organic anion transporter family, member 5A1
chr6_+_54172653 0.08 ENST00000370869.3
 TINAG
 tubulointerstitial nephritis antigen
chr6_-_29343068 0.08 ENST00000396806.3
 OR12D3
 olfactory receptor, family 12, subfamily D, member 3
chr19_+_39138271 0.08 ENST00000252699.2
 ACTN4
 actinin, alpha 4
chr15_-_99057551 0.08 ENST00000558256.1
 FAM169B
 family with sequence similarity 169, member B
chr4_-_166034029 0.08 ENST00000306480.6
 TMEM192
 transmembrane protein 192
chr3_+_66271410 0.08 ENST00000336733.6
 SLC25A26
 solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr1_+_17906970 0.07 ENST00000375415.1
 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_-_24102576 0.07 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
 SOX5
 SRY (sex determining region Y)-box 5
chr13_+_96085847 0.07 ENST00000376873.3
 CLDN10
 claudin 10
chr10_+_135340859 0.07 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
 CYP2E1
 cytochrome P450, family 2, subfamily E, polypeptide 1
chr12_+_20963647 0.07 ENST00000381545.3
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr19_-_11639910 0.07 ENST00000588998.1
ENST00000586149.1
 ECSIT
 ECSIT signalling integrator
chr12_+_20963632 0.07 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr3_-_196911002 0.07 ENST00000452595.1
 DLG1
 discs, large homolog 1 (Drosophila)
chr1_-_168464875 0.07 ENST00000422253.1
 RP5-968D22.3
 RP5-968D22.3
chr7_-_155601766 0.07 ENST00000430104.1
 SHH
 sonic hedgehog
chr11_+_560956 0.07 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
 RASSF7
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr10_+_101542462 0.07 ENST00000370449.4
ENST00000370434.1
 ABCC2
 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr22_-_27456361 0.07 ENST00000453934.1
 CTA-992D9.6
 CTA-992D9.6
chr14_+_95027772 0.07 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
 SERPINA4
SERPINA5
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr21_+_39628852 0.06 ENST00000398938.2
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_63063152 0.06 ENST00000371129.3
 ANGPTL3
 angiopoietin-like 3
chr19_-_38916839 0.06 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
 RASGRP4
 RAS guanyl releasing protein 4
chr4_+_141264597 0.06 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
 SCOC
 short coiled-coil protein
chr16_-_57831676 0.06 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
 KIFC3
 kinesin family member C3
chr22_+_32439019 0.06 ENST00000266088.4
 SLC5A1
 solute carrier family 5 (sodium/glucose cotransporter), member 1
chr12_+_40787194 0.06 ENST00000425730.2
ENST00000454784.4
 MUC19
 mucin 19, oligomeric
chr19_-_11639931 0.06 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
 ECSIT
 ECSIT signalling integrator
chr1_-_114430169 0.06 ENST00000393316.3
 BCL2L15
 BCL2-like 15
chr12_+_100897130 0.06 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
 NR1H4
 nuclear receptor subfamily 1, group H, member 4
chr3_+_183948161 0.06 ENST00000426955.2
 VWA5B2
 von Willebrand factor A domain containing 5B2
chr12_+_100750846 0.06 ENST00000323346.5
 SLC17A8
 solute carrier family 17 (vesicular glutamate transporter), member 8
chr15_+_58724184 0.06 ENST00000433326.2
 LIPC
 lipase, hepatic
chr9_-_94712434 0.06 ENST00000375708.3
 ROR2
 receptor tyrosine kinase-like orphan receptor 2
chr21_-_47575481 0.06 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
 FTCD
 formimidoyltransferase cyclodeaminase
chr5_+_6714718 0.06 ENST00000230859.6
ENST00000515721.1
 PAPD7
 PAP associated domain containing 7
chr12_-_102874416 0.05 ENST00000392904.1
ENST00000337514.6
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr11_+_20620946 0.05 ENST00000525748.1
 SLC6A5
 solute carrier family 6 (neurotransmitter transporter), member 5
chr2_+_234637754 0.05 ENST00000482026.1
ENST00000609767.1
 UGT1A3
UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr12_+_70133152 0.05 ENST00000550536.1
ENST00000362025.5
 RAB3IP
 RAB3A interacting protein
chr7_-_143956815 0.05 ENST00000493325.1
 OR2A7
 olfactory receptor, family 2, subfamily A, member 7
chr15_+_58430368 0.05 ENST00000558772.1
ENST00000219919.4
 AQP9
 aquaporin 9
chr15_+_26360970 0.05 ENST00000556159.1
ENST00000557523.1
 LINC00929
 long intergenic non-protein coding RNA 929
chr2_+_234627424 0.05 ENST00000373409.3
 UGT1A4
 UDP glucuronosyltransferase 1 family, polypeptide A4
chr15_+_58430567 0.05 ENST00000536493.1
 AQP9
 aquaporin 9
chr4_+_74269956 0.05 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
 ALB
 albumin
chr1_+_119911425 0.05 ENST00000361035.4
ENST00000325945.3
 HAO2
 hydroxyacid oxidase 2 (long chain)
chr4_+_169013666 0.05 ENST00000359299.3
 ANXA10
 annexin A10
chr9_+_140125385 0.05 ENST00000361134.2
 SLC34A3
 solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr4_+_74347400 0.05 ENST00000226355.3
 AFM
 afamin
chr10_+_5135981 0.05 ENST00000380554.3
 AKR1C3
 aldo-keto reductase family 1, member C3
chr6_-_127840021 0.05 ENST00000465909.2
 SOGA3
 SOGA family member 3
chr8_+_104892639 0.05 ENST00000436393.2
 RIMS2
 regulating synaptic membrane exocytosis 2
chr8_-_17752996 0.05 ENST00000381841.2
ENST00000427924.1
 FGL1
 fibrinogen-like 1
chr1_+_229406847 0.04 ENST00000366690.4
 RAB4A
 RAB4A, member RAS oncogene family
chr6_-_127840336 0.04 ENST00000525778.1
 SOGA3
 SOGA family member 3
chr12_-_102874378 0.04 ENST00000456098.1
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr4_+_159443024 0.04 ENST00000448688.2
 RXFP1
 relaxin/insulin-like family peptide receptor 1
chr12_+_25205666 0.04 ENST00000547044.1
 LRMP
 lymphoid-restricted membrane protein
chr2_+_234526272 0.04 ENST00000373450.4
 UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A8
chr6_-_127840453 0.04 ENST00000556132.1
 SOGA3
 SOGA family member 3
chr7_+_130126012 0.04 ENST00000341441.5
 MEST
 mesoderm specific transcript
chr11_+_46740730 0.04 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
 F2
 coagulation factor II (thrombin)
chr6_+_25754927 0.04 ENST00000377905.4
ENST00000439485.2
 SLC17A4
 solute carrier family 17, member 4
chr12_-_68553512 0.04 ENST00000229135.3
 IFNG
 interferon, gamma
chr2_+_38177575 0.04 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
 RMDN2
 regulator of microtubule dynamics 2
chr6_+_29141311 0.04 ENST00000377167.2
 OR2J2
 olfactory receptor, family 2, subfamily J, member 2
chr14_-_65409502 0.04 ENST00000389614.5
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr9_+_140125209 0.04 ENST00000538474.1
 SLC34A3
 solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr17_+_68071389 0.04 ENST00000283936.1
ENST00000392671.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr4_+_71494461 0.04 ENST00000396073.3
 ENAM
 enamelin
chr7_+_130126165 0.04 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
 MEST
 mesoderm specific transcript
chr10_-_75226166 0.04 ENST00000544628.1
 PPP3CB
 protein phosphatase 3, catalytic subunit, beta isozyme
chr7_-_87856280 0.04 ENST00000490437.1
ENST00000431660.1
 SRI
 sorcin
chr17_+_41052808 0.04 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
 G6PC
 glucose-6-phosphatase, catalytic subunit
chr18_+_5748793 0.04 ENST00000566533.1
ENST00000562452.2
 RP11-945C19.1
 RP11-945C19.1
chr9_+_130860810 0.04 ENST00000433501.1
 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr6_+_50061315 0.03 ENST00000415106.1
 RP11-397G17.1
 RP11-397G17.1
chr3_+_72200408 0.03 ENST00000473713.1
 LINC00870
 long intergenic non-protein coding RNA 870
chr7_-_87856303 0.03 ENST00000394641.3
 SRI
 sorcin
chr5_+_40841276 0.03 ENST00000254691.5
 CARD6
 caspase recruitment domain family, member 6
chr3_-_126327398 0.03 ENST00000383572.2
 TXNRD3NB
 thioredoxin reductase 3 neighbor
chr2_-_169104651 0.03 ENST00000355999.4
 STK39
 serine threonine kinase 39
chr19_+_41305085 0.03 ENST00000303961.4
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr2_-_55920952 0.03 ENST00000447944.2
 PNPT1
 polyribonucleotide nucleotidyltransferase 1
chr12_+_25205568 0.03 ENST00000548766.1
ENST00000556887.1
 LRMP
 lymphoid-restricted membrane protein
chr16_+_89696692 0.03 ENST00000261615.4
 DPEP1
 dipeptidase 1 (renal)
chrX_-_15619076 0.03 ENST00000252519.3
 ACE2
 angiotensin I converting enzyme 2
chr9_+_130860583 0.03 ENST00000373064.5
 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chrX_+_1710484 0.03 ENST00000313871.3
ENST00000381261.3
 AKAP17A
 A kinase (PRKA) anchor protein 17A
chr12_+_100867486 0.03 ENST00000548884.1
 NR1H4
 nuclear receptor subfamily 1, group H, member 4
chr17_+_68071458 0.03 ENST00000589377.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr2_+_234621551 0.03 ENST00000608381.1
ENST00000373414.3
 UGT1A1
UGT1A5
 UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr7_-_27219849 0.03 ENST00000396344.4
 HOXA10
 homeobox A10
chr11_-_83393457 0.03 ENST00000404783.3
 DLG2
 discs, large homolog 2 (Drosophila)
chr14_+_62585332 0.03 ENST00000554895.1
 LINC00643
 long intergenic non-protein coding RNA 643
chr4_+_3443614 0.03 ENST00000382774.3
ENST00000511533.1
 HGFAC
 HGF activator
chr4_-_987164 0.02 ENST00000398520.2
 SLC26A1
 solute carrier family 26 (anion exchanger), member 1
chr13_+_27825706 0.02 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
 RPL21
 ribosomal protein L21
chr11_-_117695449 0.02 ENST00000292079.2
 FXYD2
 FXYD domain containing ion transport regulator 2
chr6_+_131571535 0.02 ENST00000474850.2
 AKAP7
 A kinase (PRKA) anchor protein 7
chr4_-_69536346 0.02 ENST00000338206.5
 UGT2B15
 UDP glucuronosyltransferase 2 family, polypeptide B15
chr4_-_102267953 0.02 ENST00000523694.2
ENST00000507176.1
 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_-_420338 0.02 ENST00000450882.1
ENST00000441883.1
ENST00000447696.1
ENST00000389675.2
 MRPL28
 mitochondrial ribosomal protein L28
chr6_+_54173227 0.02 ENST00000259782.4
ENST00000370864.3
 TINAG
 tubulointerstitial nephritis antigen
chrX_-_124097620 0.02 ENST00000371130.3
ENST00000422452.2
 TENM1
 teneurin transmembrane protein 1
chr12_-_102874330 0.02 ENST00000307046.8
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr3_+_107318157 0.02 ENST00000406780.1
 BBX
 bobby sox homolog (Drosophila)
chr11_-_83393429 0.02 ENST00000426717.2
 DLG2
 discs, large homolog 2 (Drosophila)
chr12_-_8693469 0.02 ENST00000545274.1
ENST00000446457.2
 CLEC4E
 C-type lectin domain family 4, member E
chr14_-_65409438 0.02 ENST00000557049.1
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr4_-_109541539 0.02 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
 RPL34-AS1
 RPL34 antisense RNA 1 (head to head)
chr2_-_228244013 0.02 ENST00000304568.3
 TM4SF20
 transmembrane 4 L six family member 20
chr3_-_137893721 0.02 ENST00000505015.2
ENST00000260803.4
 DBR1
 debranching RNA lariats 1
chr1_+_57320437 0.02 ENST00000361249.3
 C8A
 complement component 8, alpha polypeptide
chr10_-_52645416 0.01 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
 A1CF
 APOBEC1 complementation factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1903412 response to bile acid(GO:1903412)
0.1 0.3 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.4 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.2 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.0 GO:0046137 negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340) regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.5 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0016098 response to ozone(GO:0010193) monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:1990667 PCSK9-LDLR complex(GO:1990666) PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.0 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones