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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXA10_HOXB9

Z-value: 0.52

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Transcription factors associated with HOXA10_HOXB9

Gene Symbol Gene ID Gene Info
HOXA10
ENSG00000253293.3 HOXA10
HOXB9
ENSG00000170689.8 HOXB9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA10hg19_v2_chr7_-_27219849_272198800.677.2e-02Click!
HOXB9hg19_v2_chr17_-_46703826_467038450.314.5e-01Click!

Activity profile of HOXA10_HOXB9 motif

Sorted Z-values of HOXA10_HOXB9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA10_HOXB9

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_41742697 0.90 ENST00000242208.4
 INHBA
 inhibin, beta A
chrX_+_105937068 0.86 ENST00000324342.3
 RNF128
 ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_153003671 0.71 ENST00000307098.4
 SPRR1B
 small proline-rich protein 1B
chr1_+_160370344 0.58 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chr2_-_216878305 0.49 ENST00000263268.6
 MREG
 melanoregulin
chr17_-_39646116 0.48 ENST00000328119.6
 KRT36
 keratin 36
chr7_+_128784712 0.44 ENST00000289407.4
 TSPAN33
 tetraspanin 33
chr10_-_129691195 0.37 ENST00000368671.3
 CLRN3
 clarin 3
chr5_+_140261703 0.36 ENST00000409494.1
ENST00000289272.2
 PCDHA13
 protocadherin alpha 13
chr14_-_72458326 0.34 ENST00000542853.1
 AC005477.1
 AC005477.1
chrX_-_117119243 0.32 ENST00000539496.1
ENST00000469946.1
 KLHL13
 kelch-like family member 13
chr3_+_189507432 0.31 ENST00000354600.5
 TP63
 tumor protein p63
chr7_-_143105941 0.29 ENST00000275815.3
 EPHA1
 EPH receptor A1
chr4_-_72649763 0.28 ENST00000513476.1
 GC
 group-specific component (vitamin D binding protein)
chr18_-_19994830 0.27 ENST00000525417.1
 CTAGE1
 cutaneous T-cell lymphoma-associated antigen 1
chr8_-_81083890 0.26 ENST00000518937.1
 TPD52
 tumor protein D52
chr3_-_172241250 0.25 ENST00000420541.2
ENST00000241261.2
 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
chr11_+_63606373 0.25 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr17_-_39274606 0.24 ENST00000391413.2
 KRTAP4-11
 keratin associated protein 4-11
chr1_+_46152886 0.24 ENST00000372025.4
 TMEM69
 transmembrane protein 69
chr5_+_140165876 0.24 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
 PCDHA1
 protocadherin alpha 1
chr7_+_35756092 0.24 ENST00000458087.3
 AC018647.3
 AC018647.3
chr7_+_35756186 0.23 ENST00000430518.1
 AC018647.3
 AC018647.3
chr11_+_10471836 0.22 ENST00000444303.2
 AMPD3
 adenosine monophosphate deaminase 3
chr10_+_96698406 0.21 ENST00000260682.6
 CYP2C9
 cytochrome P450, family 2, subfamily C, polypeptide 9
chr3_-_150690471 0.20 ENST00000468836.1
ENST00000328863.4
 CLRN1
 clarin 1
chr8_-_81083731 0.19 ENST00000379096.5
 TPD52
 tumor protein D52
chr20_+_10015678 0.19 ENST00000378392.1
ENST00000378380.3
 ANKEF1
 ankyrin repeat and EF-hand domain containing 1
chr18_-_52989217 0.19 ENST00000570287.2
 TCF4
 transcription factor 4
chr2_-_69180012 0.18 ENST00000481498.1
 GKN2
 gastrokine 2
chrX_-_133792480 0.18 ENST00000359237.4
 PLAC1
 placenta-specific 1
chr4_+_71263599 0.17 ENST00000399575.2
 PROL1
 proline rich, lacrimal 1
chr6_+_43738444 0.17 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
 VEGFA
 vascular endothelial growth factor A
chr18_-_52989525 0.17 ENST00000457482.3
 TCF4
 transcription factor 4
chr18_-_74839891 0.16 ENST00000581878.1
 MBP
 myelin basic protein
chr6_+_43737939 0.16 ENST00000372067.3
 VEGFA
 vascular endothelial growth factor A
chr1_+_23345943 0.16 ENST00000400181.4
ENST00000542151.1
 KDM1A
 lysine (K)-specific demethylase 1A
chr5_+_98109322 0.16 ENST00000513185.1
 RGMB
 repulsive guidance molecule family member b
chr18_-_44561988 0.16 ENST00000332567.4
 TCEB3B
 transcription elongation factor B polypeptide 3B (elongin A2)
chr1_+_23345930 0.16 ENST00000356634.3
 KDM1A
 lysine (K)-specific demethylase 1A
chr1_-_186430222 0.16 ENST00000391997.2
 PDC
 phosducin
chr12_+_20963632 0.15 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr12_+_20963647 0.15 ENST00000381545.3
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr3_+_189507523 0.15 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
 TP63
 tumor protein p63
chr2_-_69180083 0.15 ENST00000328895.4
 GKN2
 gastrokine 2
chr5_+_34915444 0.14 ENST00000336767.5
 BRIX1
 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr10_+_85933494 0.14 ENST00000372126.3
 C10orf99
 chromosome 10 open reading frame 99
chr2_-_51259229 0.14 ENST00000405472.3
 NRXN1
 neurexin 1
chr12_+_1800179 0.14 ENST00000357103.4
 ADIPOR2
 adiponectin receptor 2
chr3_+_125687987 0.14 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
 ROPN1B
 rhophilin associated tail protein 1B
chr2_-_51259292 0.14 ENST00000401669.2
 NRXN1
 neurexin 1
chr13_-_103719196 0.14 ENST00000245312.3
 SLC10A2
 solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr10_+_24755416 0.14 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
 KIAA1217
 KIAA1217
chr9_+_124413873 0.13 ENST00000408936.3
 DAB2IP
 DAB2 interacting protein
chr1_+_67773044 0.13 ENST00000262345.1
ENST00000371000.1
 IL12RB2
 interleukin 12 receptor, beta 2
chr3_+_57875711 0.13 ENST00000442599.2
 SLMAP
 sarcolemma associated protein
chr3_+_140981456 0.13 ENST00000504264.1
 ACPL2
 acid phosphatase-like 2
chr8_-_21669826 0.13 ENST00000517328.1
 GFRA2
 GDNF family receptor alpha 2
chr1_+_32379174 0.13 ENST00000391369.1
 AL136115.1
 HCG2032337; PRO1848; Uncharacterized protein
chr3_+_57875738 0.13 ENST00000417128.1
ENST00000438794.1
 SLMAP
 sarcolemma associated protein
chr4_-_76957214 0.13 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chr12_+_70219052 0.13 ENST00000552032.2
ENST00000547771.2
 MYRFL
 myelin regulatory factor-like
chr10_+_133747955 0.13 ENST00000455566.1
 PPP2R2D
 protein phosphatase 2, regulatory subunit B, delta
chr10_-_73848531 0.12 ENST00000373109.2
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_244515930 0.12 ENST00000366537.1
ENST00000308105.4
 C1orf100
 chromosome 1 open reading frame 100
chr5_-_87516448 0.12 ENST00000511218.1
 TMEM161B
 transmembrane protein 161B
chr16_-_75498553 0.11 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
 TMEM170A
RP11-77K12.1
 transmembrane protein 170A
Uncharacterized protein
chr21_-_15583165 0.11 ENST00000536861.1
 LIPI
 lipase, member I
chr2_+_234668894 0.11 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
 UGT1A8
UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_113885138 0.11 ENST00000409930.3
 IL1RN
 interleukin 1 receptor antagonist
chr2_-_71062938 0.11 ENST00000410009.3
 CD207
 CD207 molecule, langerin
chr6_+_131958436 0.11 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
 ENPP3
 ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_+_28813645 0.10 ENST00000282391.5
 PAN3
 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr6_+_111408698 0.10 ENST00000368851.5
 SLC16A10
 solute carrier family 16 (aromatic amino acid transporter), member 10
chr1_-_226926864 0.10 ENST00000429204.1
ENST00000366784.1
 ITPKB
 inositol-trisphosphate 3-kinase B
chr19_+_4402659 0.10 ENST00000301280.5
ENST00000585854.1
 CHAF1A
 chromatin assembly factor 1, subunit A (p150)
chr15_-_22448819 0.10 ENST00000604066.1
 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr6_+_25279651 0.10 ENST00000329474.6
 LRRC16A
 leucine rich repeat containing 16A
chr6_+_121756809 0.10 ENST00000282561.3
 GJA1
 gap junction protein, alpha 1, 43kDa
chr15_+_40886199 0.10 ENST00000346991.5
ENST00000528975.1
ENST00000527044.1
 CASC5
 cancer susceptibility candidate 5
chr15_+_52155001 0.09 ENST00000544199.1
 TMOD3
 tropomodulin 3 (ubiquitous)
chr9_-_85678043 0.09 ENST00000376447.3
ENST00000340717.4
 RASEF
 RAS and EF-hand domain containing
chr2_+_27440229 0.09 ENST00000264705.4
ENST00000403525.1
 CAD
 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr3_-_196911002 0.09 ENST00000452595.1
 DLG1
 discs, large homolog 1 (Drosophila)
chr10_-_24770632 0.09 ENST00000596413.1
 AL353583.1
 AL353583.1
chr1_+_248201474 0.09 ENST00000366479.2
 OR2L2
 olfactory receptor, family 2, subfamily L, member 2
chr12_-_71148357 0.09 ENST00000378778.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr17_-_10452929 0.09 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
 MYH2
 myosin, heavy chain 2, skeletal muscle, adult
chr12_-_71148413 0.09 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chrX_+_41548259 0.09 ENST00000378138.5
 GPR34
 G protein-coupled receptor 34
chr18_-_53069419 0.09 ENST00000570177.2
 TCF4
 transcription factor 4
chr4_+_155484155 0.08 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr4_+_88896819 0.08 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
 SPP1
 secreted phosphoprotein 1
chr4_-_90759440 0.08 ENST00000336904.3
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr5_+_147582387 0.08 ENST00000325630.2
 SPINK6
 serine peptidase inhibitor, Kazal type 6
chr3_+_15045419 0.08 ENST00000406272.2
 NR2C2
 nuclear receptor subfamily 2, group C, member 2
chr6_+_42584847 0.08 ENST00000372883.3
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr17_-_38821373 0.08 ENST00000394052.3
 KRT222
 keratin 222
chr10_-_73848086 0.08 ENST00000536168.1
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr8_+_1993173 0.08 ENST00000523438.1
 MYOM2
 myomesin 2
chr17_-_29624343 0.07 ENST00000247271.4
 OMG
 oligodendrocyte myelin glycoprotein
chrX_+_65384182 0.07 ENST00000441993.2
ENST00000419594.1
 HEPH
 hephaestin
chr5_-_16738451 0.07 ENST00000274203.9
ENST00000515803.1
 MYO10
 myosin X
chr14_+_56584414 0.07 ENST00000559044.1
 PELI2
 pellino E3 ubiquitin protein ligase family member 2
chr12_-_18243119 0.07 ENST00000538724.1
ENST00000229002.2
 RERGL
 RERG/RAS-like
chr7_-_25268104 0.07 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr1_-_161207953 0.07 ENST00000367982.4
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr4_+_70861647 0.07 ENST00000246895.4
ENST00000381060.2
 STATH
 statherin
chr19_-_19626838 0.07 ENST00000360913.3
 TSSK6
 testis-specific serine kinase 6
chr8_+_1993152 0.07 ENST00000262113.4
 MYOM2
 myomesin 2
chr3_-_129612394 0.07 ENST00000505616.1
ENST00000426664.2
 TMCC1
 transmembrane and coiled-coil domain family 1
chr9_-_104145795 0.07 ENST00000259407.2
 BAAT
 bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr1_-_23342340 0.07 ENST00000566855.1
 C1orf234
 chromosome 1 open reading frame 234
chr2_+_197577841 0.07 ENST00000409270.1
 CCDC150
 coiled-coil domain containing 150
chr4_+_56815102 0.07 ENST00000257287.4
 CEP135
 centrosomal protein 135kDa
chr16_-_15180257 0.07 ENST00000540462.1
 RRN3
 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chrX_+_65384052 0.07 ENST00000336279.5
ENST00000458621.1
 HEPH
 hephaestin
chr4_+_95972822 0.07 ENST00000509540.1
ENST00000440890.2
 BMPR1B
 bone morphogenetic protein receptor, type IB
chr9_+_134065506 0.07 ENST00000483497.2
 NUP214
 nucleoporin 214kDa
chr20_+_42984330 0.07 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
 HNF4A
 hepatocyte nuclear factor 4, alpha
chr2_-_209010874 0.07 ENST00000260988.4
 CRYGB
 crystallin, gamma B
chr19_-_3500635 0.07 ENST00000250937.3
 DOHH
 deoxyhypusine hydroxylase/monooxygenase
chr9_+_130026756 0.07 ENST00000314904.5
ENST00000373387.4
 GARNL3
 GTPase activating Rap/RanGAP domain-like 3
chr1_-_94147385 0.06 ENST00000260502.6
 BCAR3
 breast cancer anti-estrogen resistance 3
chr12_+_64173583 0.06 ENST00000261234.6
 TMEM5
 transmembrane protein 5
chr12_+_75728419 0.06 ENST00000378695.4
ENST00000312442.2
 GLIPR1L1
 GLI pathogenesis-related 1 like 1
chr2_-_40657397 0.06 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_68962805 0.06 ENST00000370966.5
 DEPDC1
 DEP domain containing 1
chr17_+_61086917 0.06 ENST00000424789.2
ENST00000389520.4
 TANC2
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr13_-_47012325 0.06 ENST00000409879.2
 KIAA0226L
 KIAA0226-like
chr4_-_89951028 0.06 ENST00000506913.1
 FAM13A
 family with sequence similarity 13, member A
chr4_-_123377880 0.06 ENST00000226730.4
 IL2
 interleukin 2
chr6_+_44215603 0.06 ENST00000371554.1
 HSP90AB1
 heat shock protein 90kDa alpha (cytosolic), class B member 1
chr15_-_58571445 0.06 ENST00000558231.1
 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
chr17_-_10560619 0.06 ENST00000583535.1
 MYH3
 myosin, heavy chain 3, skeletal muscle, embryonic
chr9_-_95640218 0.06 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
 ZNF484
 zinc finger protein 484
chr11_-_118972575 0.06 ENST00000432443.2
 DPAGT1
 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr4_+_88529681 0.05 ENST00000399271.1
 DSPP
 dentin sialophosphoprotein
chr17_+_7211656 0.05 ENST00000416016.2
 EIF5A
 eukaryotic translation initiation factor 5A
chr6_-_10115007 0.05 ENST00000485268.1
 OFCC1
 orofacial cleft 1 candidate 1
chr10_+_102106829 0.05 ENST00000370355.2
 SCD
 stearoyl-CoA desaturase (delta-9-desaturase)
chr7_-_50633078 0.05 ENST00000444124.2
 DDC
 dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr20_+_30697298 0.05 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr4_+_71337834 0.05 ENST00000304887.5
 MUC7
 mucin 7, secreted
chr3_-_123710893 0.05 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
 ROPN1
 rhophilin associated tail protein 1
chr9_+_125132803 0.05 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_77112244 0.05 ENST00000376896.3
 RORB
 RAR-related orphan receptor B
chr12_-_24102576 0.05 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
 SOX5
 SRY (sex determining region Y)-box 5
chr8_+_145215928 0.05 ENST00000528919.1
 MROH1
 maestro heat-like repeat family member 1
chr3_-_139396853 0.05 ENST00000406164.1
ENST00000406824.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chr2_+_32390925 0.05 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
 SLC30A6
 solute carrier family 30 (zinc transporter), member 6
chr10_-_103599591 0.05 ENST00000348850.5
 KCNIP2
 Kv channel interacting protein 2
chr17_-_39324424 0.05 ENST00000391356.2
 KRTAP4-3
 keratin associated protein 4-3
chr15_+_66797455 0.05 ENST00000446801.2
 ZWILCH
 zwilch kinetochore protein
chr20_-_50384864 0.05 ENST00000311637.5
ENST00000402822.1
 ATP9A
 ATPase, class II, type 9A
chrX_-_15619076 0.05 ENST00000252519.3
 ACE2
 angiotensin I converting enzyme 2
chr13_-_47471155 0.05 ENST00000543956.1
ENST00000542664.1
 HTR2A
 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr12_+_12510352 0.05 ENST00000298571.6
 LOH12CR1
 loss of heterozygosity, 12, chromosomal region 1
chr13_-_46626847 0.05 ENST00000242848.4
ENST00000282007.3
 ZC3H13
 zinc finger CCCH-type containing 13
chr14_+_22675388 0.04 ENST00000390461.2
 TRAV34
 T cell receptor alpha variable 34
chr19_+_1440838 0.04 ENST00000594262.1
 AC027307.3
 Uncharacterized protein
chr4_+_186317133 0.04 ENST00000507753.1
 ANKRD37
 ankyrin repeat domain 37
chr10_+_115614370 0.04 ENST00000369301.3
 NHLRC2
 NHL repeat containing 2
chr2_+_28718921 0.04 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
 PLB1
 phospholipase B1
chr14_+_31046959 0.04 ENST00000547532.1
ENST00000555429.1
 G2E3
 G2/M-phase specific E3 ubiquitin protein ligase
chr4_-_110723194 0.04 ENST00000394635.3
 CFI
 complement factor I
chr1_-_86848760 0.04 ENST00000460698.2
 ODF2L
 outer dense fiber of sperm tails 2-like
chr3_-_87325728 0.04 ENST00000350375.2
 POU1F1
 POU class 1 homeobox 1
chr3_-_139396801 0.04 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chrY_-_24038660 0.04 ENST00000382677.3
 RBMY1D
 RNA binding motif protein, Y-linked, family 1, member D
chr11_+_61717279 0.04 ENST00000378043.4
 BEST1
 bestrophin 1
chrY_+_23698778 0.04 ENST00000303902.5
 RBMY1A1
 RNA binding motif protein, Y-linked, family 1, member A1
chr10_-_50396425 0.04 ENST00000374148.1
 C10orf128
 chromosome 10 open reading frame 128
chr4_+_68424434 0.04 ENST00000265404.2
ENST00000396225.1
 STAP1
 signal transducing adaptor family member 1
chr15_+_66797627 0.04 ENST00000565627.1
ENST00000564179.1
 ZWILCH
 zwilch kinetochore protein
chr3_-_58196688 0.04 ENST00000486455.1
 DNASE1L3
 deoxyribonuclease I-like 3
chr1_-_17766198 0.04 ENST00000375436.4
 RCC2
 regulator of chromosome condensation 2
chr2_-_231989808 0.04 ENST00000258400.3
 HTR2B
 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr8_+_107738343 0.04 ENST00000521592.1
 OXR1
 oxidation resistance 1
chr1_-_54355430 0.04 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
 YIPF1
 Yip1 domain family, member 1
chr12_-_95945246 0.04 ENST00000258499.3
 USP44
 ubiquitin specific peptidase 44
chr2_+_173686303 0.04 ENST00000397087.3
 RAPGEF4
 Rap guanine nucleotide exchange factor (GEF) 4
chr21_+_34398153 0.04 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
 OLIG2
 oligodendrocyte lineage transcription factor 2
chr3_-_12200851 0.04 ENST00000287814.4
 TIMP4
 TIMP metallopeptidase inhibitor 4
chr15_+_40886439 0.04 ENST00000532056.1
ENST00000399668.2
 CASC5
 cancer susceptibility candidate 5
chr4_-_100356551 0.04 ENST00000209665.4
 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_-_57146095 0.04 ENST00000550770.1
ENST00000338193.6
 PRIM1
 primase, DNA, polypeptide 1 (49kDa)
chr8_+_128426535 0.04 ENST00000465342.2
 POU5F1B
 POU class 5 homeobox 1B
chr11_+_61717336 0.04 ENST00000378042.3
 BEST1
 bestrophin 1
chr19_-_29704448 0.04 ENST00000304863.4
 UQCRFS1
 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr3_+_149191723 0.03 ENST00000305354.4
 TM4SF4
 transmembrane 4 L six family member 4
chr1_-_161207986 0.03 ENST00000506209.1
ENST00000367980.2
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr6_+_26156551 0.03 ENST00000304218.3
 HIST1H1E
 histone cluster 1, H1e
chr11_-_5345582 0.03 ENST00000328813.2
 OR51B2
 olfactory receptor, family 51, subfamily B, member 2
chr17_-_73663245 0.03 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
 RECQL5
 RecQ protein-like 5
chr4_+_86525299 0.03 ENST00000512201.1
 ARHGAP24
 Rho GTPase activating protein 24
chr14_-_106453155 0.03 ENST00000390594.2
 IGHV1-2
 immunoglobulin heavy variable 1-2
chr4_+_155484103 0.03 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr12_-_118628350 0.03 ENST00000537952.1
ENST00000537822.1
 TAOK3
 TAO kinase 3
chr13_-_79979919 0.03 ENST00000267229.7
 RBM26
 RNA binding motif protein 26

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.6 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.9 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.0 GO:1903978 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.0 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.6 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics