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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXA5

Z-value: 1.22

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Transcription factors associated with HOXA5

Gene Symbol Gene ID Gene Info
ENSG00000106004.4 HOXA5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA5hg19_v2_chr7_-_27183263_271832870.541.7e-01Click!

Activity profile of HOXA5 motif

Sorted Z-values of HOXA5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_92413353 3.45 ENST00000556154.1
FBLN5
fibulin 5
chr14_-_92413727 3.04 ENST00000267620.10
FBLN5
fibulin 5
chr2_-_158300556 2.63 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr12_-_91574142 2.37 ENST00000547937.1
DCN
decorin
chr3_+_12392971 1.28 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr1_-_149889382 1.01 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr2_-_160919112 0.97 ENST00000283243.7
ENST00000392771.1
PLA2R1
phospholipase A2 receptor 1, 180kDa
chr17_+_19437132 0.91 ENST00000436810.2
ENST00000270570.4
ENST00000457293.1
ENST00000542886.1
ENST00000575023.1
ENST00000395585.1
SLC47A1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr1_-_232651312 0.90 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr13_+_76378305 0.88 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr1_-_227505289 0.77 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr1_+_221051699 0.74 ENST00000366903.6
HLX
H2.0-like homeobox
chr2_-_179343226 0.71 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr7_-_23510086 0.66 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_207082748 0.64 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr20_+_33292068 0.63 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chrX_+_54947229 0.62 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr19_+_50016610 0.58 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr6_+_124125286 0.57 ENST00000368416.1
ENST00000368417.1
ENST00000546092.1
NKAIN2
Na+/K+ transporting ATPase interacting 2
chr17_-_33446735 0.57 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr2_-_40657397 0.56 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_+_25963020 0.54 ENST00000357085.3
TRIM38
tripartite motif containing 38
chr7_+_99717230 0.53 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr16_+_10971037 0.52 ENST00000324288.8
ENST00000381835.5
CIITA
class II, major histocompatibility complex, transactivator
chr4_-_142054590 0.51 ENST00000306799.3
RNF150
ring finger protein 150
chr11_+_20044096 0.48 ENST00000533917.1
NAV2
neuron navigator 2
chrX_+_10124977 0.48 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr17_-_33446820 0.47 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr14_+_21156915 0.46 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr9_+_75766763 0.46 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chrX_+_55478538 0.45 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr5_+_140723601 0.44 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr9_-_123342415 0.42 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr11_-_96076334 0.42 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr6_-_116575226 0.41 ENST00000420283.1
TSPYL4
TSPY-like 4
chr22_+_46476192 0.40 ENST00000443490.1
FLJ27365
hsa-mir-4763
chrX_-_65253506 0.39 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr8_-_122653630 0.39 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr11_-_33744256 0.38 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59
CD59 molecule, complement regulatory protein
chr17_-_295730 0.37 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr6_+_155537771 0.37 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_+_116575329 0.36 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE
RP3-486I3.7
dermatan sulfate epimerase
RP3-486I3.7
chr9_-_110251836 0.36 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr11_-_33744487 0.35 ENST00000426650.2
CD59
CD59 molecule, complement regulatory protein
chr1_-_149900122 0.35 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr10_+_17270214 0.35 ENST00000544301.1
VIM
vimentin
chrX_-_118826784 0.32 ENST00000394616.4
SEPT6
septin 6
chr2_+_30670077 0.31 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
LCLAT1
lysocardiolipin acyltransferase 1
chr6_-_34216766 0.31 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chr20_-_34638841 0.29 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr8_-_123139423 0.28 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr3_+_29323043 0.27 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr1_+_84609944 0.27 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_44384291 0.27 ENST00000324394.6
ZNF404
zinc finger protein 404
chr10_+_103986085 0.25 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr2_-_61697862 0.25 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr6_-_154677900 0.25 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr9_-_127905736 0.24 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr12_-_54653313 0.24 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr1_+_152943122 0.24 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr3_-_149093499 0.21 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr10_+_18240834 0.21 ENST00000377371.3
ENST00000539911.1
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr11_+_33061543 0.20 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr7_+_44084233 0.20 ENST00000448521.1
DBNL
drebrin-like
chr10_-_127505167 0.19 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr4_+_71063641 0.19 ENST00000514097.1
ODAM
odontogenic, ameloblast asssociated
chr11_+_12399071 0.19 ENST00000539723.1
ENST00000550549.1
PARVA
parvin, alpha
chr7_-_23571586 0.19 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
TRA2A
transformer 2 alpha homolog (Drosophila)
chr14_+_24025462 0.18 ENST00000556015.1
ENST00000554970.1
ENST00000554789.1
THTPA
thiamine triphosphatase
chr11_-_2162468 0.18 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_131037623 0.17 ENST00000495313.1
ENST00000372898.2
SWI5
SWI5 recombination repair homolog (yeast)
chr7_+_44084262 0.17 ENST00000456905.1
ENST00000440166.1
ENST00000452943.1
ENST00000468694.1
ENST00000494774.1
ENST00000490734.2
DBNL
drebrin-like
chr1_-_182921119 0.16 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr6_+_140175987 0.16 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr19_-_35264089 0.15 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
ZNF599
zinc finger protein 599
chr7_-_99717463 0.15 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr3_+_127770455 0.15 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr7_-_99716952 0.15 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr13_+_76378407 0.14 ENST00000447038.1
LMO7
LIM domain 7
chr11_+_65686802 0.14 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr11_-_31531121 0.14 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_-_18610246 0.13 ENST00000379387.4
ENST00000541984.1
UEVLD
UEV and lactate/malate dehyrogenase domains
chr12_+_111051832 0.13 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr1_+_177140633 0.12 ENST00000361539.4
BRINP2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr8_-_79717750 0.12 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr1_+_154229547 0.12 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr10_+_18549645 0.12 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr16_-_66764119 0.11 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr4_+_158493642 0.11 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
RP11-364P22.1
chr4_+_25378912 0.11 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr12_+_111051902 0.11 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1
tectonic family member 1
chr3_+_186383741 0.11 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr19_-_44259136 0.11 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr3_+_37035289 0.10 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr14_+_65878565 0.10 ENST00000556518.1
ENST00000557164.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr11_+_9685604 0.10 ENST00000447399.2
ENST00000318950.6
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr10_+_18240814 0.10 ENST00000377374.4
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr1_+_171283331 0.09 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr4_+_74606223 0.09 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr6_+_168418553 0.09 ENST00000354419.2
ENST00000351261.3
KIF25
kinesin family member 25
chr3_+_174577070 0.09 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr5_+_132149017 0.08 ENST00000378693.2
SOWAHA
sosondowah ankyrin repeat domain family member A
chr17_-_38911580 0.08 ENST00000312150.4
KRT25
keratin 25
chr6_-_2751146 0.08 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr14_+_93389425 0.08 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr10_-_7708918 0.08 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr19_+_41768401 0.07 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr4_-_103749205 0.07 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr16_-_62070305 0.07 ENST00000584337.1
CDH8
cadherin 8, type 2
chr20_+_2361545 0.06 ENST00000202625.2
ENST00000381423.1
TGM6
transglutaminase 6
chr10_+_126630692 0.06 ENST00000359653.4
ZRANB1
zinc finger, RAN-binding domain containing 1
chr12_-_11150474 0.06 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr2_+_190541153 0.06 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr1_-_91487013 0.06 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr9_+_33290491 0.05 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
NFX1
nuclear transcription factor, X-box binding 1
chr7_-_92855762 0.05 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr6_+_131958436 0.05 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr3_-_157221128 0.05 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr4_+_86525299 0.05 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr16_-_72128270 0.04 ENST00000426362.2
TXNL4B
thioredoxin-like 4B
chr6_-_9977801 0.04 ENST00000316020.6
ENST00000491508.1
OFCC1
orofacial cleft 1 candidate 1
chr8_+_55528627 0.04 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr8_+_38065104 0.03 ENST00000521311.1
BAG4
BCL2-associated athanogene 4
chr4_-_103746683 0.03 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_75262629 0.03 ENST00000434412.2
GDAP1
ganglioside induced differentiation associated protein 1
chr5_+_140552218 0.03 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr1_+_153950202 0.02 ENST00000608236.1
RP11-422P24.11
RP11-422P24.11
chr22_-_41682172 0.02 ENST00000356244.3
RANGAP1
Ran GTPase activating protein 1
chr9_+_140125385 0.02 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr19_-_44259053 0.02 ENST00000601170.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr10_-_97200772 0.02 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr6_+_29426230 0.02 ENST00000442615.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr1_-_154150651 0.02 ENST00000302206.5
TPM3
tropomyosin 3
chr8_+_92261516 0.02 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr10_-_115904361 0.02 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr3_+_238273 0.01 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr5_+_76326187 0.01 ENST00000312916.7
ENST00000506806.1
AGGF1
angiogenic factor with G patch and FHA domains 1
chr13_+_30510003 0.01 ENST00000400540.1
LINC00544
long intergenic non-protein coding RNA 544
chr2_+_114163945 0.01 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr19_-_54604083 0.01 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR
osteoclast associated, immunoglobulin-like receptor
chr3_+_179322481 0.01 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr2_+_74154032 0.00 ENST00000356837.6
DGUOK
deoxyguanosine kinase
chr8_-_135522425 0.00 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr1_-_63988846 0.00 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr1_-_197169672 0.00 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr14_+_102276209 0.00 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr4_+_71296204 0.00 ENST00000413702.1
MUC7
mucin 7, secreted
chr21_-_35884573 0.00 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr6_-_24666819 0.00 ENST00000341060.3
TDP2
tyrosyl-DNA phosphodiesterase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.4 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.3 1.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.7 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.2 2.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 1.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.9 GO:0046618 drug export(GO:0046618)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0046606 negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0006915 apoptotic process(GO:0006915)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.5 GO:0071953 elastic fiber(GO:0071953)
0.2 2.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 1.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.7 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.0 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 6.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 6.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA