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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXB6_PRRX2

Z-value: 1.83

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Transcription factors associated with HOXB6_PRRX2

Gene Symbol Gene ID Gene Info
ENSG00000108511.8 HOXB6
ENSG00000167157.9 PRRX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRRX2hg19_v2_chr9_+_132427883_132427951-0.791.9e-02Click!
HOXB6hg19_v2_chr17_-_46682321_46682362-0.196.6e-01Click!

Activity profile of HOXB6_PRRX2 motif

Sorted Z-values of HOXB6_PRRX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_92413353 9.23 ENST00000556154.1
FBLN5
fibulin 5
chr12_-_91576750 8.41 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN
decorin
chr12_-_91576561 8.25 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chr14_-_92413727 7.78 ENST00000267620.10
FBLN5
fibulin 5
chr12_-_91576429 7.76 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr2_-_145278475 7.38 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr3_+_141105705 4.05 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_145277569 3.92 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr16_+_53133070 3.54 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_-_57045228 3.48 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr13_+_102104980 3.39 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_+_160188889 3.24 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr13_-_67802549 3.17 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr13_+_102104952 3.06 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_91574142 2.97 ENST00000547937.1
DCN
decorin
chr14_-_92414055 2.89 ENST00000342058.4
FBLN5
fibulin 5
chr12_-_91546926 2.78 ENST00000550758.1
DCN
decorin
chr12_-_91539918 2.77 ENST00000548218.1
DCN
decorin
chr5_-_111093759 2.70 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr15_+_93443419 2.54 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr9_-_95186739 2.52 ENST00000375550.4
OMD
osteomodulin
chr5_-_88119580 2.47 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr2_+_210444748 2.46 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr7_-_14026063 2.44 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr3_+_69928256 2.44 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr5_-_20575959 2.35 ENST00000507958.1
CDH18
cadherin 18, type 2
chr13_-_38172863 2.34 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr3_+_69985734 2.34 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr5_+_156712372 2.28 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_-_145277640 2.27 ENST00000539609.3
ZEB2
zinc finger E-box binding homeobox 2
chr13_+_102142296 2.26 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_210444142 2.25 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr4_-_138453606 2.24 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr3_+_141106458 2.22 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_-_111092930 2.21 ENST00000257435.7
NREP
neuronal regeneration related protein
chr8_-_120651020 2.20 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr3_+_69812877 2.17 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr13_+_76334498 2.16 ENST00000534657.1
LMO7
LIM domain 7
chr11_-_27723158 2.10 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr3_+_69812701 2.09 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr6_-_87804815 2.03 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr8_+_77593474 2.01 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr5_-_111093167 1.99 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr9_-_20622478 1.96 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_175711133 1.93 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr6_-_46293378 1.92 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr7_-_14026123 1.89 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr16_-_51185172 1.86 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr2_+_33359646 1.85 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr3_-_114477787 1.85 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_77593448 1.84 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr4_+_55095264 1.82 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_+_33359687 1.82 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr8_-_122653630 1.75 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr20_-_34025999 1.70 ENST00000374369.3
GDF5
growth differentiation factor 5
chr6_+_136172820 1.68 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr8_-_108510224 1.68 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr3_-_114477962 1.63 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr10_-_49812997 1.62 ENST00000417912.2
ARHGAP22
Rho GTPase activating protein 22
chr9_+_2159850 1.62 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_76334795 1.61 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr7_-_27142290 1.60 ENST00000222718.5
HOXA2
homeobox A2
chr2_-_224467093 1.58 ENST00000305409.2
SCG2
secretogranin II
chr6_-_85474219 1.57 ENST00000369663.5
TBX18
T-box 18
chr5_+_95066823 1.57 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr5_+_67586465 1.55 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr13_+_76378357 1.49 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr8_-_93107443 1.48 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_155537771 1.45 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_-_111092873 1.43 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr7_-_27183263 1.42 ENST00000222726.3
HOXA5
homeobox A5
chr1_-_232651312 1.41 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr5_+_82767583 1.40 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr5_+_156696362 1.39 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr10_-_49813090 1.37 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr14_-_61116168 1.36 ENST00000247182.6
SIX1
SIX homeobox 1
chr3_-_112360116 1.35 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr3_+_157154578 1.35 ENST00000295927.3
PTX3
pentraxin 3, long
chr5_+_173316341 1.35 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr13_+_76334567 1.34 ENST00000321797.8
LMO7
LIM domain 7
chr1_+_162602244 1.33 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr16_+_53242350 1.32 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr5_+_82767487 1.32 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr5_+_145718587 1.32 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chrX_+_9431324 1.31 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr18_-_25616519 1.28 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr8_+_97597148 1.26 ENST00000521590.1
SDC2
syndecan 2
chr2_+_54785485 1.26 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_+_119799927 1.25 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr1_+_168250194 1.24 ENST00000367821.3
TBX19
T-box 19
chr9_-_95244781 1.21 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr10_-_106240032 1.21 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr9_-_123812542 1.20 ENST00000223642.1
C5
complement component 5
chr7_-_14029283 1.20 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr3_+_12392971 1.19 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr4_+_129730947 1.18 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr13_+_76378305 1.18 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr5_-_124081008 1.18 ENST00000306315.5
ZNF608
zinc finger protein 608
chr5_-_61031495 1.18 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr1_+_155829286 1.15 ENST00000368324.4
SYT11
synaptotagmin XI
chr16_+_86612112 1.14 ENST00000320241.3
FOXL1
forkhead box L1
chr3_+_141105235 1.13 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_-_232598163 1.12 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr17_-_56082455 1.11 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr2_-_200322723 1.08 ENST00000417098.1
SATB2
SATB homeobox 2
chr4_+_129730779 1.07 ENST00000226319.6
PHF17
jade family PHD finger 1
chr3_+_141106643 1.07 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_148447887 1.06 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr1_+_65730385 1.04 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_-_19988339 1.03 ENST00000382275.1
CDH18
cadherin 18, type 2
chr5_-_111093081 1.02 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr10_-_33623310 1.00 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr2_-_45236540 0.99 ENST00000303077.6
SIX2
SIX homeobox 2
chr4_+_129730839 0.99 ENST00000511647.1
PHF17
jade family PHD finger 1
chr2_+_152214098 0.98 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_33172012 0.98 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr3_+_69985792 0.98 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr1_+_223101757 0.97 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr3_-_71353892 0.97 ENST00000484350.1
FOXP1
forkhead box P1
chr5_-_41510725 0.96 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr5_-_41510656 0.96 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr2_+_33172221 0.95 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr10_-_92681033 0.95 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_+_174844645 0.94 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr5_-_111091948 0.94 ENST00000447165.2
NREP
neuronal regeneration related protein
chr6_-_152639479 0.94 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr12_+_54422142 0.93 ENST00000243108.4
HOXC6
homeobox C6
chr3_+_12330560 0.93 ENST00000397026.2
PPARG
peroxisome proliferator-activated receptor gamma
chr8_-_120685608 0.92 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr11_+_20044096 0.92 ENST00000533917.1
NAV2
neuron navigator 2
chr13_+_36050881 0.91 ENST00000537702.1
NBEA
neurobeachin
chr3_+_69915385 0.91 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr3_-_114790179 0.91 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_124080203 0.91 ENST00000504926.1
ZNF608
zinc finger protein 608
chr10_+_69865866 0.91 ENST00000354393.2
MYPN
myopalladin
chr5_+_59783540 0.90 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr6_+_72926145 0.90 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr10_-_21786179 0.87 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr5_-_111093340 0.87 ENST00000508870.1
NREP
neuronal regeneration related protein
chr8_-_93107696 0.86 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_39623681 0.85 ENST00000225899.3
KRT32
keratin 32
chr8_+_70404996 0.84 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr11_+_12766583 0.84 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr16_-_3350614 0.84 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr1_-_227505289 0.83 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr4_-_41884620 0.82 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr2_-_175462934 0.82 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr18_-_70532906 0.80 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr9_+_2158443 0.80 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_2015335 0.80 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr18_-_30353025 0.78 ENST00000359358.4
KLHL14
kelch-like family member 14
chr5_-_111093406 0.78 ENST00000379671.3
NREP
neuronal regeneration related protein
chr9_-_13165457 0.78 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr1_+_104293028 0.77 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr8_-_72268889 0.76 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr4_+_170581213 0.75 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr9_+_2158485 0.75 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_32711419 0.74 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr5_+_174151536 0.73 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr4_-_138453559 0.73 ENST00000511115.1
PCDH18
protocadherin 18
chr12_+_79258444 0.73 ENST00000261205.4
SYT1
synaptotagmin I
chr2_-_99279928 0.72 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_145277882 0.72 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_190044480 0.72 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr12_+_109785708 0.72 ENST00000310903.5
MYO1H
myosin IH
chr11_-_96076334 0.72 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr16_+_53241854 0.71 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_-_158300556 0.71 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr8_-_25281747 0.71 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr1_-_68698222 0.70 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr8_-_72268968 0.69 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_241799232 0.69 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr14_-_53331239 0.69 ENST00000553663.1
FERMT2
fermitin family member 2
chr14_-_37051798 0.68 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr1_+_61869748 0.67 ENST00000357977.5
NFIA
nuclear factor I/A
chr19_+_2476116 0.67 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr15_+_96869165 0.67 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_+_62067860 0.67 ENST00000514591.1
LPHN3
latrophilin 3
chr5_+_140792614 0.66 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr12_+_79258547 0.66 ENST00000457153.2
SYT1
synaptotagmin I
chr3_+_141103634 0.66 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr6_+_12717892 0.66 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr7_-_80141328 0.64 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr4_+_88754113 0.64 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chrX_+_100333709 0.63 ENST00000372930.4
TMEM35
transmembrane protein 35
chr3_+_152017924 0.63 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr11_+_120973375 0.63 ENST00000264037.2
TECTA
tectorin alpha
chr3_-_71294304 0.62 ENST00000498215.1
FOXP1
forkhead box P1
chr2_+_179318295 0.62 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr7_+_90339169 0.62 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr1_-_68698197 0.61 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr1_-_104238912 0.61 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr4_+_71457970 0.61 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr5_+_140810132 0.61 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr12_+_60058458 0.60 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chrX_+_22050546 0.60 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr14_+_51955831 0.60 ENST00000356218.4
FRMD6
FERM domain containing 6
chr5_-_121413974 0.59 ENST00000231004.4
LOX
lysyl oxidase
chr17_-_39191107 0.59 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr3_+_63953415 0.59 ENST00000484332.1
ATXN7
ataxin 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 14.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
2.2 32.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.5 20.0 GO:0048251 elastic fiber assembly(GO:0048251)
1.2 3.6 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.7 2.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.7 2.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.6 1.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.6 1.8 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.6 1.8 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.6 5.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.5 3.8 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.5 2.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 1.6 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.5 1.4 GO:0060435 bronchiole development(GO:0060435)
0.5 2.3 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.5 2.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.5 0.9 GO:0097325 melanocyte proliferation(GO:0097325)
0.5 1.8 GO:0072092 ureteric bud invasion(GO:0072092)
0.4 1.7 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 1.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.4 3.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 1.2 GO:1990927 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.4 1.4 GO:0009956 radial pattern formation(GO:0009956)
0.3 1.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.3 1.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 2.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 1.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 1.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.7 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 1.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.7 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 1.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 10.2 GO:0030318 melanocyte differentiation(GO:0030318)
0.2 1.3 GO:0008218 bioluminescence(GO:0008218)
0.2 0.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 5.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.0 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 3.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.8 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.2 0.8 GO:0018032 protein amidation(GO:0018032)
0.2 0.6 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.2 0.7 GO:1990637 response to prolactin(GO:1990637)
0.2 1.6 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.2 3.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 1.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 2.7 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.2 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.6 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.6 GO:0060023 soft palate development(GO:0060023)
0.1 1.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.6 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.5 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.9 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 1.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.0 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 1.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.1 5.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 1.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.3 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0021650 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 1.2 GO:0060539 diaphragm development(GO:0060539)
0.1 0.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.1 0.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.7 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.2 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.2 GO:0051180 vitamin transport(GO:0051180)
0.1 0.9 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.4 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.2 GO:0070168 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.1 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.1 GO:2000538 T-helper 1 cell activation(GO:0035711) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 3.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 2.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 1.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 4.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.0 GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.5 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.3 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 2.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.0 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 4.6 GO:0007286 spermatid development(GO:0007286)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.7 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.1 GO:1902882 regulation of response to oxidative stress(GO:1902882)
0.0 0.0 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.5 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 2.6 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.3 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 5.6 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0048278 vesicle docking involved in exocytosis(GO:0006904) membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.0 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.4 GO:0060004 reflex(GO:0060004)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0035150 regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.3 GO:0031269 pseudopodium assembly(GO:0031269)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.5 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 7.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.2 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.1 GO:0021554 optic nerve development(GO:0021554)
0.0 6.0 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.3 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.0 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.2 GO:0016577 histone demethylation(GO:0016577)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 32.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.1 21.2 GO:0071953 elastic fiber(GO:0071953)
1.2 4.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 2.0 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 1.9 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 5.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.4 GO:0032437 cuticular plate(GO:0032437)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 4.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.3 GO:0016342 catenin complex(GO:0016342)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.9 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.9 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 1.9 GO:0010369 chromocenter(GO:0010369)
0.1 9.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 1.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 2.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 7.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 4.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.8 GO:0005902 microvillus(GO:0005902)
0.0 2.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.0 GO:0060171 stereocilium membrane(GO:0060171)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 4.0 GO:0005770 late endosome(GO:0005770)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 5.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.0 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0050436 microfibril binding(GO:0050436)
0.8 3.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.7 2.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.6 3.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.4 1.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 1.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 1.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 32.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 1.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 2.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 15.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 1.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 2.3 GO:0050692 DBD domain binding(GO:0050692)
0.2 9.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.0 GO:0043559 insulin binding(GO:0043559)
0.2 1.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.8 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.5 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.4 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0016160 amylase activity(GO:0016160)
0.1 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 3.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 1.2 GO:0036122 BMP binding(GO:0036122)
0.1 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 4.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 13.2 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.0 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 3.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 19.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 2.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 1.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.8 GO:0004386 helicase activity(GO:0004386)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 2.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.4 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 9.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 4.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151) transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 40.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 12.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 27.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 3.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 35.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 4.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 3.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 2.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 3.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.6 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 3.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation