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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXD1

Z-value: 0.53

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Transcription factors associated with HOXD1

Gene Symbol Gene ID Gene Info
ENSG00000128645.11 HOXD1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD1hg19_v2_chr2_+_177053307_1770534020.521.9e-01Click!

Activity profile of HOXD1 motif

Sorted Z-values of HOXD1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_151034734 0.64 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr19_-_36001113 0.48 ENST00000434389.1
DMKN
dermokine
chr11_-_102651343 0.46 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr5_+_66300446 0.44 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_+_111718036 0.36 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_111718173 0.35 ENST00000494932.1
TAGLN3
transgelin 3
chr3_+_111717600 0.35 ENST00000273368.4
TAGLN3
transgelin 3
chr4_+_144354644 0.32 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr3_+_111717511 0.32 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr4_-_74486217 0.31 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_25865159 0.30 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr11_+_65554493 0.22 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr9_-_5339873 0.21 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr12_+_29376673 0.20 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr20_-_50418972 0.20 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr20_-_50418947 0.20 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr12_+_29376592 0.20 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr20_-_50419055 0.19 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr3_-_191000172 0.18 ENST00000427544.2
UTS2B
urotensin 2B
chr4_-_74486109 0.18 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_74486347 0.16 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr17_-_27418537 0.16 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr11_-_124190184 0.15 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chrX_+_107288239 0.15 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr12_+_10163231 0.14 ENST00000396502.1
ENST00000338896.5
CLEC12B
C-type lectin domain family 12, member B
chr6_+_130339710 0.12 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr9_+_124329336 0.11 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr8_-_49834299 0.10 ENST00000396822.1
SNAI2
snail family zinc finger 2
chrX_+_107288197 0.10 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr8_-_49833978 0.09 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr2_-_99871570 0.08 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr2_+_228736335 0.08 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr17_-_10372875 0.08 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr14_+_56584414 0.08 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chrX_+_114827818 0.07 ENST00000420625.2
PLS3
plastin 3
chr11_+_60163775 0.07 ENST00000300187.6
ENST00000395005.2
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr1_+_117544366 0.06 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr1_-_201140673 0.06 ENST00000367333.2
TMEM9
transmembrane protein 9
chr13_-_36050819 0.06 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr17_-_38956205 0.06 ENST00000306658.7
KRT28
keratin 28
chr4_+_86748898 0.06 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr2_+_135596180 0.06 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_-_10022735 0.06 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr3_-_126327398 0.05 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr3_+_129247479 0.05 ENST00000296271.3
RHO
rhodopsin
chr12_-_22063787 0.05 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_+_135596106 0.05 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr5_+_63802109 0.05 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr15_+_58702742 0.05 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr1_-_92952433 0.05 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr4_+_86749045 0.05 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr12_+_28410128 0.04 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr10_+_99205894 0.04 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr11_+_73498898 0.04 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr19_-_3557570 0.04 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr10_+_99205959 0.04 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr12_-_23737534 0.04 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr7_-_73256838 0.03 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr11_+_118398178 0.03 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr11_-_71823715 0.03 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr12_-_52761262 0.03 ENST00000257901.3
KRT85
keratin 85
chr11_-_71823266 0.03 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr10_-_72142345 0.03 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20
leucine rich repeat containing 20
chr11_-_71823796 0.03 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr18_-_33709268 0.02 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chrX_+_43515467 0.02 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr14_+_32798547 0.02 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr4_-_139051839 0.01 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616
long intergenic non-protein coding RNA 616
chr4_-_138453559 0.01 ENST00000511115.1
PCDH18
protocadherin 18
chr18_-_44181442 0.01 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr11_+_71900703 0.01 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr3_-_101039402 0.01 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr12_-_118797475 0.01 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr15_-_55562479 0.01 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr10_-_99205607 0.01 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr5_-_96478466 0.01 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr19_+_11071546 0.01 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr14_+_32798462 0.01 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr3_-_99569821 0.01 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr7_-_81399329 0.00 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_+_77154935 0.00 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.4 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism