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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXD10

Z-value: 0.85

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Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
ENSG00000128710.5 HOXD10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg19_v2_chr2_+_176981307_1769813070.393.4e-01Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_40198527 1.33 ENST00000381799.5
RHOH
ras homolog family member H
chr18_+_29027696 1.11 ENST00000257189.4
DSG3
desmoglein 3
chr2_-_161056762 0.88 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr2_-_161056802 0.78 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr1_-_242612779 0.76 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr19_-_6690723 0.75 ENST00000601008.1
C3
complement component 3
chr18_+_61445007 0.74 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_62439037 0.72 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr4_+_77356248 0.68 ENST00000296043.6
SHROOM3
shroom family member 3
chr2_-_165424973 0.66 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr19_-_51456321 0.63 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr17_+_48610074 0.61 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr5_+_140227048 0.58 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr5_+_140254884 0.56 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr4_-_77328458 0.55 ENST00000388914.3
ENST00000434846.2
CCDC158
coiled-coil domain containing 158
chr2_+_68961934 0.55 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr7_-_22233442 0.54 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_68961905 0.54 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr6_+_36097992 0.54 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chrX_-_102565858 0.53 ENST00000449185.1
ENST00000536889.1
BEX2
brain expressed X-linked 2
chr2_+_207804278 0.48 ENST00000272852.3
CPO
carboxypeptidase O
chr12_+_20963647 0.45 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_+_63137251 0.45 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr12_+_20963632 0.44 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_+_186798073 0.43 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr12_-_12674032 0.43 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr2_+_68962014 0.38 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chrX_-_102565932 0.38 ENST00000372674.1
ENST00000372677.3
BEX2
brain expressed X-linked 2
chr8_-_66701319 0.37 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr16_+_30751953 0.36 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr12_-_56882136 0.35 ENST00000311966.4
GLS2
glutaminase 2 (liver, mitochondrial)
chr3_+_46412345 0.35 ENST00000292303.4
CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr1_+_62417957 0.31 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr11_-_79151695 0.31 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr6_-_132967142 0.30 ENST00000275216.1
TAAR1
trace amine associated receptor 1
chr2_-_165698662 0.30 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr18_-_19994830 0.29 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr17_-_38938786 0.27 ENST00000301656.3
KRT27
keratin 27
chr2_-_89521942 0.26 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr15_+_26360970 0.26 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr20_+_52105495 0.26 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr14_+_76776957 0.25 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr1_-_153113927 0.25 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr10_+_6625605 0.25 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr9_+_71944241 0.25 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr8_-_95274536 0.24 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr4_-_90758227 0.24 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_41831485 0.23 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr14_-_72458326 0.23 ENST00000542853.1
AC005477.1
AC005477.1
chr4_-_90756769 0.22 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr18_+_55816546 0.22 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_29324054 0.22 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr4_-_76944621 0.22 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr18_-_19997878 0.22 ENST00000391403.2
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr22_-_29107919 0.22 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr13_+_78109884 0.22 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr8_+_124084899 0.22 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31
TBC1 domain family, member 31
chr3_+_140981456 0.21 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr3_+_57881966 0.21 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr13_+_78109804 0.21 ENST00000535157.1
SCEL
sciellin
chr6_+_121756809 0.20 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr18_-_44561988 0.20 ENST00000332567.4
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr4_-_89951028 0.20 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr17_-_4463856 0.20 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr3_+_136676707 0.20 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr11_-_104769141 0.20 ENST00000508062.1
ENST00000422698.2
CASP12
caspase 12 (gene/pseudogene)
chr7_-_111032971 0.20 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_155942086 0.19 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_+_90211643 0.19 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr10_-_120925054 0.19 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
SFXN4
sideroflexin 4
chr12_-_25055177 0.19 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr4_-_72649763 0.19 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr6_-_32557610 0.19 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr4_+_100432161 0.19 ENST00000326581.4
ENST00000514652.1
C4orf17
chromosome 4 open reading frame 17
chr16_-_30122717 0.19 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr3_-_27498235 0.19 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr16_-_20556492 0.18 ENST00000568098.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chrX_+_37639302 0.18 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr22_+_29469012 0.18 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr19_-_53770972 0.17 ENST00000311170.4
VN1R4
vomeronasal 1 receptor 4
chr2_+_89998789 0.17 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr13_+_32313658 0.17 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr18_-_61329118 0.17 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr4_-_47983519 0.17 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr13_-_47012325 0.17 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr1_-_149459549 0.16 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr3_+_57882024 0.16 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr10_-_52008313 0.16 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr9_+_125376948 0.16 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr7_+_129847688 0.16 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr21_-_31588365 0.16 ENST00000399899.1
CLDN8
claudin 8
chr4_+_155484155 0.16 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_-_84035868 0.15 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr1_+_152975488 0.15 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr3_-_185538849 0.15 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr12_-_91451758 0.15 ENST00000266719.3
KERA
keratocan
chr2_+_118572226 0.15 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr4_+_76481258 0.15 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr20_-_17539456 0.15 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr11_-_104827425 0.15 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_-_99870744 0.15 ENST00000409238.1
ENST00000423800.1
LYG2
lysozyme G-like 2
chr5_-_137475071 0.15 ENST00000265191.2
NME5
NME/NM23 family member 5
chr10_+_5488564 0.14 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr6_+_26365443 0.14 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr3_+_158288942 0.14 ENST00000491767.1
ENST00000355893.5
MLF1
myeloid leukemia factor 1
chr18_-_3845293 0.14 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_1418154 0.14 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr2_+_102456277 0.13 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_126327398 0.13 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr10_+_695888 0.13 ENST00000441152.2
PRR26
proline rich 26
chr11_+_122753391 0.13 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr4_+_15341442 0.13 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr4_-_123377880 0.13 ENST00000226730.4
IL2
interleukin 2
chr12_-_71148413 0.13 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr12_-_100656134 0.13 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr1_-_111743285 0.12 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr12_-_16759711 0.12 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_124279627 0.12 ENST00000357082.4
ZHX1-C8ORF76
ZHX1-C8ORF76 readthrough
chr4_-_68749745 0.12 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr17_-_10452929 0.12 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr10_+_96522361 0.12 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr12_-_71148357 0.12 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr4_-_68749699 0.12 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr7_+_141490017 0.11 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr1_-_156399184 0.11 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chr4_-_69434245 0.11 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr9_+_103189405 0.11 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr6_+_37897735 0.11 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr4_-_153332886 0.11 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr6_-_142409936 0.11 ENST00000258042.1
NMBR
neuromedin B receptor
chr2_+_90273679 0.11 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr10_-_62332357 0.11 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_-_20212630 0.11 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr8_-_70016408 0.11 ENST00000518540.1
RP11-600K15.1
RP11-600K15.1
chr11_-_58980342 0.11 ENST00000361050.3
MPEG1
macrophage expressed 1
chr3_+_63428982 0.11 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr8_-_28347737 0.11 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr1_+_244214577 0.11 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr21_-_27423339 0.11 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr11_-_27528301 0.11 ENST00000524596.1
ENST00000278193.2
LIN7C
lin-7 homolog C (C. elegans)
chr6_+_96025341 0.10 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr17_+_66624280 0.10 ENST00000585484.1
RP11-118B18.1
RP11-118B18.1
chr10_+_116697946 0.10 ENST00000298746.3
TRUB1
TruB pseudouridine (psi) synthase family member 1
chr19_+_49588677 0.10 ENST00000598984.1
ENST00000598441.1
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr6_-_170101749 0.10 ENST00000448612.1
WDR27
WD repeat domain 27
chr5_+_140174429 0.10 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
PCDHA2
protocadherin alpha 2
chr3_+_158288960 0.10 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
MLF1
myeloid leukemia factor 1
chr1_+_109256067 0.10 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr12_+_118814344 0.10 ENST00000397564.2
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr11_+_55594695 0.10 ENST00000378397.1
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr12_+_118814185 0.10 ENST00000543473.1
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr6_+_27791862 0.10 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr2_-_74875432 0.10 ENST00000536235.1
ENST00000421985.1
M1AP
meiosis 1 associated protein
chrX_-_138914394 0.10 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr17_+_40925454 0.10 ENST00000253794.2
ENST00000590339.1
ENST00000589520.1
VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr6_-_32498046 0.09 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr6_+_131958436 0.09 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr3_+_196466710 0.09 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr3_-_120461353 0.09 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr1_+_180199393 0.09 ENST00000263726.2
LHX4
LIM homeobox 4
chr2_+_157330081 0.09 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr9_-_104145795 0.09 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr16_-_71610985 0.09 ENST00000355962.4
TAT
tyrosine aminotransferase
chr7_-_38305279 0.09 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr2_+_183982238 0.09 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35
nucleoporin 35kDa
chr17_-_17480779 0.09 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr3_-_172859017 0.09 ENST00000351008.3
SPATA16
spermatogenesis associated 16
chr2_-_90538397 0.09 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr11_+_7110165 0.09 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chr10_+_120967072 0.09 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr16_-_15180257 0.09 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr3_+_130569429 0.09 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr9_-_47314222 0.09 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chrX_+_149887090 0.08 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr2_+_234590556 0.08 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr16_+_78056412 0.08 ENST00000299642.4
ENST00000575655.1
CLEC3A
C-type lectin domain family 3, member A
chr9_+_4839762 0.08 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chr2_+_87565634 0.08 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr12_-_13248732 0.08 ENST00000396302.3
GSG1
germ cell associated 1
chr17_+_27369918 0.08 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr6_+_123100853 0.08 ENST00000356535.4
FABP7
fatty acid binding protein 7, brain
chr2_-_105030466 0.08 ENST00000449772.1
AC068535.3
AC068535.3
chr3_+_35721106 0.08 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr18_-_22932080 0.08 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521
chr8_+_26150628 0.08 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_-_194119083 0.08 ENST00000401815.1
GP5
glycoprotein V (platelet)
chr3_-_128206759 0.08 ENST00000430265.2
GATA2
GATA binding protein 2
chr14_-_82089405 0.08 ENST00000554211.1
RP11-799P8.1
RP11-799P8.1
chr14_+_31046959 0.08 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr6_+_31021225 0.08 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr1_+_40713573 0.08 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr12_-_13248705 0.07 ENST00000396310.2
GSG1
germ cell associated 1
chr1_-_242162375 0.07 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr15_+_76352178 0.07 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr9_+_27109133 0.07 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr12_+_48876275 0.07 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr3_-_167191814 0.07 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr2_+_135011731 0.07 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr12_-_13248562 0.07 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chrX_+_37639264 0.07 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 1.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.6 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.5 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.7 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.0 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.7 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.2 GO:0070990 snRNP binding(GO:0070990)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 3.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint