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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRF6_IRF4_IRF5

Z-value: 0.64

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Transcription factors associated with IRF6_IRF4_IRF5

Gene Symbol Gene ID Gene Info
IRF6
ENSG00000117595.6 IRF6
IRF4
ENSG00000137265.10 IRF4
IRF5
ENSG00000128604.14 IRF5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF6hg19_v2_chr1_-_209979465_2099794940.979.1e-05Click!
IRF5hg19_v2_chr7_+_128577972_1285780470.938.5e-04Click!
IRF4hg19_v2_chr6_+_391739_391759-0.294.8e-01Click!

Activity profile of IRF6_IRF4_IRF5 motif

Sorted Z-values of IRF6_IRF4_IRF5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF6_IRF4_IRF5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_118134997 2.35 ENST00000278937.2
 MPZL2
 myelin protein zero-like 2
chr11_-_118135160 1.89 ENST00000438295.2
 MPZL2
 myelin protein zero-like 2
chr8_+_8559406 0.85 ENST00000519106.1
 CLDN23
 claudin 23
chr12_+_113344755 0.80 ENST00000550883.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_-_10836919 0.74 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
 SFTA1P
 surfactant associated 1, pseudogene
chr15_+_41136586 0.73 ENST00000431806.1
 SPINT1
 serine peptidase inhibitor, Kunitz type 1
chr11_+_32851487 0.70 ENST00000257836.3
 PRRG4
 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr12_+_113344811 0.68 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_-_39677971 0.66 ENST00000393976.2
 KRT15
 keratin 15
chr12_+_113376157 0.62 ENST00000228928.7
 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
chr10_-_10836865 0.59 ENST00000446372.2
 SFTA1P
 surfactant associated 1, pseudogene
chr12_+_113344582 0.59 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_86889769 0.50 ENST00000370565.4
 CLCA2
 chloride channel accessory 2
chr2_-_70780572 0.48 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr9_-_32526184 0.46 ENST00000545044.1
ENST00000379868.1
 DDX58
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_+_130029457 0.46 ENST00000278742.5
 ST14
 suppression of tumorigenicity 14 (colon carcinoma)
chr5_+_68788594 0.44 ENST00000396442.2
ENST00000380766.2
 OCLN
 occludin
chr17_-_7164410 0.43 ENST00000574070.1
 CLDN7
 claudin 7
chr10_+_134210672 0.40 ENST00000305233.5
ENST00000368609.4
 PWWP2B
 PWWP domain containing 2B
chr1_-_59043166 0.39 ENST00000371225.2
 TACSTD2
 tumor-associated calcium signal transducer 2
chr9_-_32526299 0.38 ENST00000379882.1
ENST00000379883.2
 DDX58
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr21_+_42733870 0.38 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
 MX2
 myxovirus (influenza virus) resistance 2 (mouse)
chr7_-_20256965 0.37 ENST00000400331.5
ENST00000332878.4
 MACC1
 metastasis associated in colon cancer 1
chr2_+_163175394 0.36 ENST00000446271.1
ENST00000429691.2
 GCA
 grancalcin, EF-hand calcium binding protein
chr4_-_89080003 0.36 ENST00000237612.3
 ABCG2
 ATP-binding cassette, sub-family G (WHITE), member 2
chr1_-_160990886 0.36 ENST00000537746.1
 F11R
 F11 receptor
chr1_-_159915386 0.36 ENST00000361509.3
ENST00000368094.1
 IGSF9
 immunoglobulin superfamily, member 9
chr15_-_45670924 0.34 ENST00000396659.3
 GATM
 glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_+_120770686 0.33 ENST00000331393.4
ENST00000443124.1
 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
chr21_+_42792442 0.33 ENST00000398600.2
 MX1
 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr2_+_68961934 0.31 ENST00000409202.3
 ARHGAP25
 Rho GTPase activating protein 25
chr2_+_68961905 0.31 ENST00000295381.3
 ARHGAP25
 Rho GTPase activating protein 25
chr4_+_89378261 0.30 ENST00000264350.3
 HERC5
 HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr4_+_144257915 0.29 ENST00000262995.4
 GAB1
 GRB2-associated binding protein 1
chr4_-_100575781 0.28 ENST00000511828.1
 RP11-766F14.2
 Protein LOC285556
chr16_+_30751953 0.27 ENST00000483578.1
 RP11-2C24.4
 RP11-2C24.4
chr11_-_104817919 0.26 ENST00000533252.1
 CASP4
 caspase 4, apoptosis-related cysteine peptidase
chr6_+_43738444 0.25 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
 VEGFA
 vascular endothelial growth factor A
chr11_+_128563652 0.25 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr7_+_30323923 0.23 ENST00000323037.4
 ZNRF2
 zinc and ring finger 2
chr11_+_65554493 0.23 ENST00000335987.3
 OVOL1
 ovo-like zinc finger 1
chr6_+_106546808 0.22 ENST00000369089.3
 PRDM1
 PR domain containing 1, with ZNF domain
chr10_+_71561649 0.22 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
 COL13A1
 collagen, type XIII, alpha 1
chr3_-_182880541 0.22 ENST00000470251.1
ENST00000265598.3
 LAMP3
 lysosomal-associated membrane protein 3
chr12_+_46123448 0.22 ENST00000334344.6
 ARID2
 AT rich interactive domain 2 (ARID, RFX-like)
chr14_-_102552659 0.22 ENST00000441629.2
 HSP90AA1
 heat shock protein 90kDa alpha (cytosolic), class A member 1
chr21_-_34914394 0.22 ENST00000361093.5
ENST00000381815.4
 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr21_+_42798094 0.21 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
 MX1
 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr10_+_71561630 0.21 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
 COL13A1
 collagen, type XIII, alpha 1
chr2_-_163175133 0.19 ENST00000421365.2
ENST00000263642.2
 IFIH1
 interferon induced with helicase C domain 1
chr1_+_179262905 0.19 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
 SOAT1
 sterol O-acyltransferase 1
chr13_-_46961580 0.18 ENST00000378787.3
ENST00000378797.2
ENST00000429979.1
ENST00000378781.3
 KIAA0226L
 KIAA0226-like
chr13_-_76056250 0.17 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
 TBC1D4
 TBC1 domain family, member 4
chr2_+_68962014 0.17 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr5_-_35230434 0.17 ENST00000504500.1
 PRLR
 prolactin receptor
chr6_+_26087509 0.15 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
 HFE
 hemochromatosis
chr2_+_113299990 0.15 ENST00000537335.1
ENST00000417433.2
 POLR1B
 polymerase (RNA) I polypeptide B, 128kDa
chr20_+_20033158 0.15 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
 C20orf26
 chromosome 20 open reading frame 26
chr4_+_144258021 0.14 ENST00000262994.4
 GAB1
 GRB2-associated binding protein 1
chr2_-_220252603 0.14 ENST00000322176.7
ENST00000273075.4
 DNPEP
 aspartyl aminopeptidase
chrX_-_110655391 0.14 ENST00000356915.2
ENST00000356220.3
 DCX
 doublecortin
chrX_-_30877837 0.14 ENST00000378930.3
 TAB3
 TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr2_-_55920952 0.13 ENST00000447944.2
 PNPT1
 polyribonucleotide nucleotidyltransferase 1
chr12_-_31477072 0.13 ENST00000454658.2
 FAM60A
 family with sequence similarity 60, member A
chr12_+_113376249 0.13 ENST00000551007.1
ENST00000548514.1
 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
chr16_-_74734672 0.13 ENST00000306247.7
ENST00000575686.1
 MLKL
 mixed lineage kinase domain-like
chr1_-_153514241 0.13 ENST00000368718.1
ENST00000359215.1
 S100A5
 S100 calcium binding protein A5
chr2_-_231989808 0.13 ENST00000258400.3
 HTR2B
 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr2_+_7017796 0.13 ENST00000382040.3
 RSAD2
 radical S-adenosyl methionine domain containing 2
chr6_-_137365402 0.12 ENST00000541547.1
 IL20RA
 interleukin 20 receptor, alpha
chr15_-_26108355 0.12 ENST00000356865.6
 ATP10A
 ATPase, class V, type 10A
chr6_+_89855765 0.12 ENST00000275072.4
 PM20D2
 peptidase M20 domain containing 2
chr1_-_109940550 0.12 ENST00000256637.6
 SORT1
 sortilin 1
chr6_+_26087646 0.12 ENST00000309234.6
 HFE
 hemochromatosis
chr4_-_11431188 0.12 ENST00000510712.1
 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr19_+_41222998 0.11 ENST00000263370.2
 ITPKC
 inositol-trisphosphate 3-kinase C
chr14_+_39736582 0.11 ENST00000556148.1
ENST00000348007.3
 CTAGE5
 CTAGE family, member 5
chr7_-_77045617 0.11 ENST00000257626.7
 GSAP
 gamma-secretase activating protein
chr5_-_176057518 0.11 ENST00000393693.2
 SNCB
 synuclein, beta
chr3_-_179169181 0.11 ENST00000497513.1
 GNB4
 guanine nucleotide binding protein (G protein), beta polypeptide 4
chr3_+_118892362 0.11 ENST00000497685.1
ENST00000264234.3
 UPK1B
 uroplakin 1B
chr8_-_22926526 0.11 ENST00000347739.3
ENST00000542226.1
 TNFRSF10B
 tumor necrosis factor receptor superfamily, member 10b
chr12_-_50616382 0.10 ENST00000552783.1
 LIMA1
 LIM domain and actin binding 1
chr10_+_71561704 0.10 ENST00000520267.1
 COL13A1
 collagen, type XIII, alpha 1
chr2_-_75938115 0.10 ENST00000321027.3
 GCFC2
 GC-rich sequence DNA-binding factor 2
chr15_-_30114231 0.10 ENST00000356107.6
ENST00000545208.2
 TJP1
 tight junction protein 1
chr11_+_100862811 0.10 ENST00000303130.2
 TMEM133
 transmembrane protein 133
chr2_-_170219079 0.09 ENST00000263816.3
 LRP2
 low density lipoprotein receptor-related protein 2
chr20_-_25038804 0.09 ENST00000323482.4
 ACSS1
 acyl-CoA synthetase short-chain family member 1
chr11_+_63655987 0.09 ENST00000509502.2
ENST00000512060.1
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr8_-_22926623 0.09 ENST00000276431.4
 TNFRSF10B
 tumor necrosis factor receptor superfamily, member 10b
chr5_-_35938674 0.09 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
 CAPSL
 calcyphosine-like
chr3_+_127634069 0.09 ENST00000405109.1
 KBTBD12
 kelch repeat and BTB (POZ) domain containing 12
chr19_+_7600584 0.09 ENST00000600737.1
 PNPLA6
 patatin-like phospholipase domain containing 6
chr6_-_27799305 0.09 ENST00000357549.2
 HIST1H4K
 histone cluster 1, H4k
chr15_+_74287009 0.09 ENST00000395135.3
 PML
 promyelocytic leukemia
chr9_-_139640458 0.09 ENST00000476567.1
 LCN6
 lipocalin 6
chr4_+_147096837 0.09 ENST00000296581.5
ENST00000502781.1
 LSM6
 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr18_+_42260861 0.09 ENST00000282030.5
 SETBP1
 SET binding protein 1
chr2_-_111435610 0.09 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
 BUB1
 BUB1 mitotic checkpoint serine/threonine kinase
chr5_-_95297534 0.08 ENST00000513343.1
ENST00000431061.2
 ELL2
 elongation factor, RNA polymerase II, 2
chrX_-_54824673 0.08 ENST00000218436.6
 ITIH6
 inter-alpha-trypsin inhibitor heavy chain family, member 6
chr4_+_57371509 0.08 ENST00000360096.2
 ARL9
 ADP-ribosylation factor-like 9
chr15_+_90544532 0.08 ENST00000268154.4
 ZNF710
 zinc finger protein 710
chr4_-_88141755 0.08 ENST00000273963.5
 KLHL8
 kelch-like family member 8
chr16_+_12058961 0.08 ENST00000053243.1
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr15_+_28624878 0.08 ENST00000450328.2
 GOLGA8F
 golgin A8 family, member F
chr9_-_33264676 0.08 ENST00000472232.3
ENST00000379704.2
 BAG1
 BCL2-associated athanogene
chr7_+_141478242 0.08 ENST00000247881.2
 TAS2R4
 taste receptor, type 2, member 4
chr1_-_54355430 0.08 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
 YIPF1
 Yip1 domain family, member 1
chr9_+_95820966 0.08 ENST00000375472.3
ENST00000465709.1
 SUSD3
 sushi domain containing 3
chr10_+_15139394 0.08 ENST00000441850.1
 RPP38
 ribonuclease P/MRP 38kDa subunit
chr11_-_85522172 0.08 ENST00000316356.4
ENST00000389960.4
ENST00000527523.1
 SYTL2
 synaptotagmin-like 2
chr3_+_45429998 0.08 ENST00000265537.3
ENST00000415258.1
ENST00000431023.1
ENST00000414984.1
 LARS2
 leucyl-tRNA synthetase 2, mitochondrial
chr22_+_36044411 0.08 ENST00000409652.4
 APOL6
 apolipoprotein L, 6
chr12_-_71148413 0.08 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr6_-_167797887 0.07 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
 TCP10
 t-complex 10
chr9_-_103115185 0.07 ENST00000374902.4
 TEX10
 testis expressed 10
chr4_-_75719896 0.07 ENST00000395743.3
 BTC
 betacellulin
chr12_+_46123682 0.07 ENST00000422737.1
 ARID2
 AT rich interactive domain 2 (ARID, RFX-like)
chr7_+_37960163 0.07 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
 EPDR1
 ependymin related 1
chr10_+_123923205 0.07 ENST00000369004.3
ENST00000260733.3
 TACC2
 transforming, acidic coiled-coil containing protein 2
chr14_+_94577074 0.07 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
 IFI27
 interferon, alpha-inducible protein 27
chr1_-_44497024 0.07 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_144303093 0.07 ENST00000505913.1
 GAB1
 GRB2-associated binding protein 1
chr18_-_33647487 0.07 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
 RPRD1A
 regulation of nuclear pre-mRNA domain containing 1A
chr19_-_41222775 0.07 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
 ADCK4
 aarF domain containing kinase 4
chr16_+_12059050 0.07 ENST00000396495.3
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr17_-_46799872 0.07 ENST00000290294.3
 PRAC1
 prostate cancer susceptibility candidate 1
chr18_-_812517 0.07 ENST00000584307.1
 YES1
 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chrM_+_9207 0.07 ENST00000362079.2
 MT-CO3
 mitochondrially encoded cytochrome c oxidase III
chr17_+_7387677 0.07 ENST00000322644.6
 POLR2A
 polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr7_-_33080506 0.06 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
 NT5C3A
 5'-nucleotidase, cytosolic IIIA
chr18_-_812231 0.06 ENST00000314574.4
 YES1
 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr1_-_44497118 0.06 ENST00000537678.1
ENST00000466926.1
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_-_79885576 0.06 ENST00000574686.1
ENST00000357736.4
 MAFG
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr17_+_79373540 0.06 ENST00000307745.7
 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
chr6_-_100016678 0.06 ENST00000523799.1
ENST00000520429.1
 CCNC
 cyclin C
chr15_+_43425672 0.06 ENST00000260403.2
 TMEM62
 transmembrane protein 62
chr6_-_82462425 0.06 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
 FAM46A
 family with sequence similarity 46, member A
chr8_+_40018977 0.06 ENST00000520487.1
 RP11-470M17.2
 RP11-470M17.2
chr17_+_18380051 0.06 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
 LGALS9C
 lectin, galactoside-binding, soluble, 9C
chr3_+_159706537 0.06 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
 IL12A
 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr2_+_85811525 0.06 ENST00000306384.4
 VAMP5
 vesicle-associated membrane protein 5
chr9_-_133814455 0.06 ENST00000448616.1
 FIBCD1
 fibrinogen C domain containing 1
chr9_-_77643307 0.06 ENST00000376834.3
ENST00000376830.3
 C9orf41
 chromosome 9 open reading frame 41
chr4_-_48782259 0.06 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
 FRYL
 FRY-like
chr10_+_71562180 0.06 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
 COL13A1
 collagen, type XIII, alpha 1
chr15_+_74287118 0.06 ENST00000563500.1
 PML
 promyelocytic leukemia
chr2_-_160473114 0.06 ENST00000392783.2
 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
chr6_+_139349817 0.06 ENST00000367660.3
 ABRACL
 ABRA C-terminal like
chr16_-_28518153 0.06 ENST00000356897.1
 IL27
 interleukin 27
chr11_-_47736896 0.05 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
 AGBL2
 ATP/GTP binding protein-like 2
chr2_-_106810742 0.05 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
 UXS1
 UDP-glucuronate decarboxylase 1
chrX_-_45710920 0.05 ENST00000456532.1
 RP5-1158E12.3
 RP5-1158E12.3
chr2_-_106810783 0.05 ENST00000283148.7
 UXS1
 UDP-glucuronate decarboxylase 1
chr5_-_61699698 0.05 ENST00000506390.1
ENST00000199320.4
 DIMT1
 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
chr15_-_30113676 0.05 ENST00000400011.2
 TJP1
 tight junction protein 1
chr5_-_95297678 0.05 ENST00000237853.4
 ELL2
 elongation factor, RNA polymerase II, 2
chr7_-_150779995 0.05 ENST00000462940.1
ENST00000492838.1
ENST00000392818.3
ENST00000488752.1
ENST00000476627.1
 TMUB1
 transmembrane and ubiquitin-like domain containing 1
chr6_-_94129244 0.05 ENST00000369303.4
ENST00000369297.1
 EPHA7
 EPH receptor A7
chr11_+_72983246 0.05 ENST00000393590.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr18_+_3466248 0.05 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
 RP11-838N2.4
 RP11-838N2.4
chrX_+_65382433 0.05 ENST00000374727.3
 HEPH
 hephaestin
chr2_+_32390925 0.05 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
 SLC30A6
 solute carrier family 30 (zinc transporter), member 6
chr2_-_112642267 0.05 ENST00000341068.3
 ANAPC1
 anaphase promoting complex subunit 1
chr2_-_74753332 0.05 ENST00000451518.1
ENST00000404568.3
 DQX1
 DEAQ box RNA-dependent ATPase 1
chr12_-_99548645 0.05 ENST00000549025.2
 ANKS1B
 ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_90589402 0.05 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
 CDK20
 cyclin-dependent kinase 20
chr1_+_179050512 0.05 ENST00000367627.3
 TOR3A
 torsin family 3, member A
chr15_+_83478370 0.05 ENST00000286760.4
 WHAMM
 WAS protein homolog associated with actin, golgi membranes and microtubules
chr12_-_104350898 0.05 ENST00000552940.1
ENST00000547975.1
ENST00000549478.1
ENST00000546540.1
ENST00000546819.1
ENST00000378090.4
ENST00000547945.1
 C12orf73
 chromosome 12 open reading frame 73
chr2_-_74753305 0.05 ENST00000393951.2
 DQX1
 DEAQ box RNA-dependent ATPase 1
chr16_-_88851618 0.05 ENST00000301015.9
 PIEZO1
 piezo-type mechanosensitive ion channel component 1
chr11_-_19082216 0.04 ENST00000329773.2
 MRGPRX2
 MAS-related GPR, member X2
chr4_-_88141615 0.04 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
 KLHL8
 kelch-like family member 8
chr1_+_179051160 0.04 ENST00000367625.4
ENST00000352445.6
 TOR3A
 torsin family 3, member A
chr10_+_15139330 0.04 ENST00000378202.5
ENST00000378197.4
 RPP38
 ribonuclease P/MRP 38kDa subunit
chr13_-_100624012 0.04 ENST00000267294.4
 ZIC5
 Zic family member 5
chr2_-_7005785 0.04 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
 CMPK2
 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr6_-_88411911 0.04 ENST00000257787.5
 AKIRIN2
 akirin 2
chr3_-_46037299 0.04 ENST00000296137.2
 FYCO1
 FYVE and coiled-coil domain containing 1
chr2_+_124782857 0.04 ENST00000431078.1
 CNTNAP5
 contactin associated protein-like 5
chr12_+_62654119 0.04 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
 USP15
 ubiquitin specific peptidase 15
chr17_+_4643337 0.04 ENST00000592813.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr9_+_33265011 0.04 ENST00000419016.2
 CHMP5
 charged multivesicular body protein 5
chr1_-_168464875 0.04 ENST00000422253.1
 RP5-968D22.3
 RP5-968D22.3
chr13_+_98794810 0.04 ENST00000595437.1
 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_+_42300548 0.04 ENST00000344550.4
 CEACAM3
 carcinoembryonic antigen-related cell adhesion molecule 3
chr3_-_151176497 0.04 ENST00000282466.3
 IGSF10
 immunoglobulin superfamily, member 10
chr1_-_53018654 0.04 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
 ZCCHC11
 zinc finger, CCHC domain containing 11
chr2_-_75937994 0.04 ENST00000409857.3
ENST00000470503.1
ENST00000541687.1
ENST00000442309.1
 GCFC2
 GC-rich sequence DNA-binding factor 2
chr10_+_121410882 0.04 ENST00000369085.3
 BAG3
 BCL2-associated athanogene 3
chr12_+_70133152 0.04 ENST00000550536.1
ENST00000362025.5
 RAB3IP
 RAB3A interacting protein
chr1_+_110993795 0.04 ENST00000271331.3
 PROK1
 prokineticin 1
chr19_+_18942761 0.04 ENST00000599848.1
 UPF1
 UPF1 regulator of nonsense transcripts homolog (yeast)
chr15_-_65117807 0.04 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
 PIF1
 PIF1 5'-to-3' DNA helicase
chr2_-_197664366 0.03 ENST00000409364.3
ENST00000263956.3
 GTF3C3
 general transcription factor IIIC, polypeptide 3, 102kDa
chr19_+_36705504 0.03 ENST00000456324.1
 ZNF146
 zinc finger protein 146
chr12_+_4758264 0.03 ENST00000266544.5
 NDUFA9
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.1 GO:1902003 regulation of beta-amyloid formation(GO:1902003)
0.1 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.9 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0034165 regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 4.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.0 GO:0032899 regulation of neurotrophin production(GO:0032899)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0051005 nerve growth factor signaling pathway(GO:0038180) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions