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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRX3

Z-value: 0.83

Motif logo

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Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
IRX3
ENSG00000177508.11 IRX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg19_v2_chr16_-_54320675_543207150.856.8e-03Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_91574142 2.20 ENST00000547937.1
 DCN
 decorin
chr12_-_91573132 2.01 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chr12_-_91573316 1.92 ENST00000393155.1
 DCN
 decorin
chr13_-_38172863 1.69 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chr12_-_91546926 1.68 ENST00000550758.1
 DCN
 decorin
chr2_+_189839046 1.19 ENST00000304636.3
ENST00000317840.5
 COL3A1
 collagen, type III, alpha 1
chr3_+_8543393 1.13 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
 LMCD1
 LIM and cysteine-rich domains 1
chr11_-_35547572 1.00 ENST00000378880.2
 PAMR1
 peptidase domain containing associated with muscle regeneration 1
chr3_+_157154578 0.92 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr1_+_145524891 0.81 ENST00000369304.3
 ITGA10
 integrin, alpha 10
chr5_+_32788945 0.71 ENST00000326958.1
 AC026703.1
 AC026703.1
chr4_-_70626314 0.69 ENST00000510821.1
 SULT1B1
 sulfotransferase family, cytosolic, 1B, member 1
chr19_-_44388116 0.68 ENST00000587539.1
 ZNF404
 zinc finger protein 404
chr5_-_75919253 0.67 ENST00000296641.4
 F2RL2
 coagulation factor II (thrombin) receptor-like 2
chr12_+_56114189 0.65 ENST00000548082.1
 RDH5
 retinol dehydrogenase 5 (11-cis/9-cis)
chr2_+_233527443 0.65 ENST00000410095.1
 EFHD1
 EF-hand domain family, member D1
chr1_+_97188188 0.65 ENST00000541987.1
 PTBP2
 polypyrimidine tract binding protein 2
chr6_-_117747015 0.63 ENST00000368508.3
ENST00000368507.3
 ROS1
 c-ros oncogene 1 , receptor tyrosine kinase
chr12_+_56114151 0.63 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
 RDH5
 retinol dehydrogenase 5 (11-cis/9-cis)
chr8_-_108510224 0.62 ENST00000517746.1
ENST00000297450.3
 ANGPT1
 angiopoietin 1
chr3_+_8543533 0.62 ENST00000454244.1
 LMCD1
 LIM and cysteine-rich domains 1
chr3_-_9994021 0.60 ENST00000411976.2
ENST00000412055.1
 PRRT3
 proline-rich transmembrane protein 3
chr13_+_76362974 0.60 ENST00000497947.2
 LMO7
 LIM domain 7
chr12_-_58329819 0.59 ENST00000551421.1
 RP11-620J15.3
 RP11-620J15.3
chr1_-_85870177 0.56 ENST00000542148.1
 DDAH1
 dimethylarginine dimethylaminohydrolase 1
chr20_-_18477862 0.56 ENST00000337227.4
 RBBP9
 retinoblastoma binding protein 9
chr1_+_155829286 0.55 ENST00000368324.4
 SYT11
 synaptotagmin XI
chr12_-_10605929 0.54 ENST00000347831.5
ENST00000359151.3
 KLRC1
 killer cell lectin-like receptor subfamily C, member 1
chr3_+_12392971 0.53 ENST00000287820.6
 PPARG
 peroxisome proliferator-activated receptor gamma
chr9_+_90112767 0.52 ENST00000408954.3
 DAPK1
 death-associated protein kinase 1
chr10_+_60272814 0.51 ENST00000373886.3
 BICC1
 bicaudal C homolog 1 (Drosophila)
chr9_+_99690592 0.51 ENST00000354649.3
 NUTM2G
 NUT family member 2G
chr4_-_70725856 0.50 ENST00000226444.3
 SULT1E1
 sulfotransferase family 1E, estrogen-preferring, member 1
chr2_-_190044480 0.50 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr1_+_171060018 0.48 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
 FMO3
 flavin containing monooxygenase 3
chr9_-_95244781 0.48 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr3_+_8543561 0.48 ENST00000397386.3
 LMCD1
 LIM and cysteine-rich domains 1
chr4_+_70894130 0.47 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3
 histatin 3
chr12_+_4671352 0.47 ENST00000542744.1
 DYRK4
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr3_+_69928256 0.46 ENST00000394355.2
 MITF
 microphthalmia-associated transcription factor
chr5_-_75919217 0.44 ENST00000504899.1
 F2RL2
 coagulation factor II (thrombin) receptor-like 2
chr7_-_92777606 0.44 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
 SAMD9L
 sterile alpha motif domain containing 9-like
chr12_+_1738363 0.44 ENST00000397196.2
 WNT5B
 wingless-type MMTV integration site family, member 5B
chr12_+_21679220 0.43 ENST00000256969.2
 C12orf39
 chromosome 12 open reading frame 39
chr15_-_56757329 0.42 ENST00000260453.3
 MNS1
 meiosis-specific nuclear structural 1
chr16_+_1578674 0.40 ENST00000253934.5
 TMEM204
 transmembrane protein 204
chr15_+_41057818 0.38 ENST00000558467.1
 GCHFR
 GTP cyclohydrolase I feedback regulator
chr12_-_91573249 0.38 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
 DCN
 decorin
chr9_-_21202204 0.38 ENST00000239347.3
 IFNA7
 interferon, alpha 7
chr12_+_71833550 0.37 ENST00000266674.5
 LGR5
 leucine-rich repeat containing G protein-coupled receptor 5
chr11_-_111782484 0.37 ENST00000533971.1
 CRYAB
 crystallin, alpha B
chr2_-_127963343 0.36 ENST00000335247.7
 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
chr2_-_158300556 0.36 ENST00000264192.3
 CYTIP
 cytohesin 1 interacting protein
chr11_+_20044600 0.35 ENST00000311043.8
 NAV2
 neuron navigator 2
chr11_-_111782696 0.35 ENST00000227251.3
ENST00000526180.1
 CRYAB
 crystallin, alpha B
chr17_-_63822563 0.35 ENST00000317442.8
 CEP112
 centrosomal protein 112kDa
chr18_-_70532906 0.34 ENST00000299430.2
ENST00000397929.1
 NETO1
 neuropilin (NRP) and tolloid (TLL)-like 1
chr1_-_46598371 0.33 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chrX_-_57147902 0.33 ENST00000275988.5
ENST00000434397.1
ENST00000333933.3
ENST00000374912.5
 SPIN2B
 spindlin family, member 2B
chrX_-_57147748 0.33 ENST00000374910.3
 SPIN2B
 spindlin family, member 2B
chr7_+_33169142 0.33 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
 BBS9
 Bardet-Biedl syndrome 9
chr1_-_46598284 0.32 ENST00000423209.1
ENST00000262741.5
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr12_+_32655048 0.32 ENST00000427716.2
ENST00000266482.3
 FGD4
 FYVE, RhoGEF and PH domain containing 4
chr12_+_8309630 0.30 ENST00000396570.3
 ZNF705A
 zinc finger protein 705A
chr1_+_144173162 0.30 ENST00000356801.6
 NBPF8
 neuroblastoma breakpoint family, member 8
chr17_-_33760164 0.30 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
 SLFN12
 schlafen family member 12
chr3_-_49851313 0.29 ENST00000333486.3
 UBA7
 ubiquitin-like modifier activating enzyme 7
chr10_+_90660832 0.29 ENST00000371924.1
 STAMBPL1
 STAM binding protein-like 1
chr17_-_29648761 0.28 ENST00000247270.3
ENST00000462804.2
 EVI2A
 ecotropic viral integration site 2A
chr20_-_33732952 0.28 ENST00000541621.1
 EDEM2
 ER degradation enhancer, mannosidase alpha-like 2
chr15_+_49170083 0.27 ENST00000530028.2
 EID1
 EP300 interacting inhibitor of differentiation 1
chr10_-_90712520 0.27 ENST00000224784.6
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr6_-_15586238 0.26 ENST00000462989.2
 DTNBP1
 dystrobrevin binding protein 1
chr15_-_63448973 0.26 ENST00000462430.1
 RPS27L
 ribosomal protein S27-like
chr7_-_16685422 0.26 ENST00000306999.2
 ANKMY2
 ankyrin repeat and MYND domain containing 2
chr3_-_127541194 0.26 ENST00000453507.2
 MGLL
 monoglyceride lipase
chr22_+_20193905 0.26 ENST00000609602.1
 LINC00896
 long intergenic non-protein coding RNA 896
chr12_+_133757995 0.26 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
 ZNF268
 zinc finger protein 268
chr5_+_140571902 0.26 ENST00000239446.4
 PCDHB10
 protocadherin beta 10
chr7_+_141811539 0.25 ENST00000550469.2
ENST00000477922.3
 RP11-1220K2.2
 Putative inactive maltase-glucoamylase-like protein LOC93432
chr3_+_138066539 0.25 ENST00000289104.4
 MRAS
 muscle RAS oncogene homolog
chr12_-_127174806 0.25 ENST00000545853.1
ENST00000537478.1
 RP11-407A16.3
 RP11-407A16.3
chr19_-_22379753 0.25 ENST00000397121.2
 ZNF676
 zinc finger protein 676
chr17_-_67264947 0.24 ENST00000586811.1
 ABCA5
 ATP-binding cassette, sub-family A (ABC1), member 5
chr17_-_33760269 0.24 ENST00000452764.3
 SLFN12
 schlafen family member 12
chr11_+_126152954 0.24 ENST00000392679.1
 TIRAP
 toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr19_-_44952635 0.24 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
 ZNF229
 zinc finger protein 229
chr15_-_89089860 0.24 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
 DET1
 de-etiolated homolog 1 (Arabidopsis)
chr4_+_56212505 0.23 ENST00000505210.1
 SRD5A3
 steroid 5 alpha-reductase 3
chr16_+_21689835 0.23 ENST00000286149.4
ENST00000388958.3
 OTOA
 otoancorin
chr19_-_9092018 0.23 ENST00000397910.4
 MUC16
 mucin 16, cell surface associated
chr20_+_54933971 0.23 ENST00000371384.3
ENST00000437418.1
 FAM210B
 family with sequence similarity 210, member B
chr6_-_111804905 0.23 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_+_79347577 0.23 ENST00000233735.1
 REG1A
 regenerating islet-derived 1 alpha
chr14_+_100485712 0.23 ENST00000544450.2
 EVL
 Enah/Vasp-like
chr3_+_51895621 0.23 ENST00000333127.3
 IQCF2
 IQ motif containing F2
chr3_+_142838091 0.23 ENST00000309575.3
 CHST2
 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr5_+_137203465 0.23 ENST00000239926.4
 MYOT
 myotilin
chr3_-_151102529 0.22 ENST00000302632.3
 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
chr15_+_67420441 0.22 ENST00000558894.1
 SMAD3
 SMAD family member 3
chr7_+_20687017 0.22 ENST00000258738.6
 ABCB5
 ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr10_-_28287968 0.22 ENST00000305242.5
 ARMC4
 armadillo repeat containing 4
chr14_+_95047725 0.22 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
 SERPINA5
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr14_+_95047744 0.22 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
 SERPINA5
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr12_-_10573149 0.22 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
 KLRC3
 killer cell lectin-like receptor subfamily C, member 3
chr12_+_55248289 0.22 ENST00000308796.6
 MUCL1
 mucin-like 1
chr8_+_22429205 0.22 ENST00000520207.1
 SORBS3
 sorbin and SH3 domain containing 3
chr5_+_110559603 0.21 ENST00000512453.1
 CAMK4
 calcium/calmodulin-dependent protein kinase IV
chr3_-_127441406 0.21 ENST00000487473.1
ENST00000484451.1
 MGLL
 monoglyceride lipase
chr12_+_75874460 0.21 ENST00000266659.3
 GLIPR1
 GLI pathogenesis-related 1
chr9_-_21305312 0.21 ENST00000259555.4
 IFNA5
 interferon, alpha 5
chr15_+_92006567 0.21 ENST00000554333.1
 RP11-661P17.1
 RP11-661P17.1
chr16_+_22501658 0.21 ENST00000415833.2
 NPIPB5
 nuclear pore complex interacting protein family, member B5
chr3_-_183543301 0.21 ENST00000318631.3
ENST00000431348.1
 MAP6D1
 MAP6 domain containing 1
chr5_+_169010638 0.20 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
 SPDL1
 spindle apparatus coiled-coil protein 1
chr2_-_88427568 0.20 ENST00000393750.3
ENST00000295834.3
 FABP1
 fatty acid binding protein 1, liver
chrX_-_83757399 0.20 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
 HDX
 highly divergent homeobox
chr1_-_154909329 0.20 ENST00000368467.3
 PMVK
 phosphomevalonate kinase
chr1_-_112032284 0.20 ENST00000414219.1
 ADORA3
 adenosine A3 receptor
chr15_+_25200108 0.20 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
 SNURF
SNRPN
 SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr5_+_175490540 0.20 ENST00000515817.1
 FAM153B
 family with sequence similarity 153, member B
chr4_-_129209944 0.20 ENST00000520121.1
 PGRMC2
 progesterone receptor membrane component 2
chr12_-_92536433 0.20 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
 C12orf79
 chromosome 12 open reading frame 79
chr1_-_89488510 0.19 ENST00000564665.1
ENST00000370481.4
 GBP3
 guanylate binding protein 3
chr3_-_50378235 0.19 ENST00000357043.2
 RASSF1
 Ras association (RalGDS/AF-6) domain family member 1
chr14_+_22386325 0.19 ENST00000390439.2
 TRAV13-2
 T cell receptor alpha variable 13-2
chr5_-_93447333 0.19 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
 FAM172A
 family with sequence similarity 172, member A
chr12_-_13256571 0.19 ENST00000545401.1
ENST00000432710.2
ENST00000351606.6
 GSG1
 germ cell associated 1
chr11_-_134123142 0.19 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
 THYN1
 thymocyte nuclear protein 1
chr19_-_36909528 0.19 ENST00000392161.3
ENST00000392171.1
 ZFP82
 ZFP82 zinc finger protein
chr10_+_91092241 0.18 ENST00000371811.4
 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
chr9_+_42704004 0.18 ENST00000457288.1
 CBWD7
 COBW domain containing 7
chr1_-_198509804 0.18 ENST00000489986.1
ENST00000367382.1
 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr4_-_83769996 0.18 ENST00000511338.1
 SEC31A
 SEC31 homolog A (S. cerevisiae)
chr2_-_207629997 0.18 ENST00000454776.2
 MDH1B
 malate dehydrogenase 1B, NAD (soluble)
chr2_+_46926048 0.18 ENST00000306503.5
 SOCS5
 suppressor of cytokine signaling 5
chr8_+_58890917 0.18 ENST00000522992.1
 RP11-1112C15.1
 RP11-1112C15.1
chr5_+_81601166 0.18 ENST00000439350.1
 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
chrX_+_52513455 0.18 ENST00000446098.1
 XAGE1C
 X antigen family, member 1C
chr10_-_4285923 0.18 ENST00000418372.1
ENST00000608792.1
 LINC00702
 long intergenic non-protein coding RNA 702
chr1_-_227505289 0.18 ENST00000366765.3
 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
chr20_+_1099233 0.18 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
 PSMF1
 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr3_+_14058794 0.18 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
 TPRXL
 tetra-peptide repeat homeobox-like
chr19_-_40596828 0.18 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
 ZNF780A
 zinc finger protein 780A
chr16_+_33204156 0.18 ENST00000398667.4
 TP53TG3C
 TP53 target 3C
chr17_-_295730 0.17 ENST00000329099.4
 FAM101B
 family with sequence similarity 101, member B
chr4_-_83812402 0.17 ENST00000395310.2
 SEC31A
 SEC31 homolog A (S. cerevisiae)
chr6_-_111804393 0.17 ENST00000368802.3
ENST00000368805.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr5_-_177207634 0.17 ENST00000513554.1
ENST00000440605.3
 FAM153A
 family with sequence similarity 153, member A
chr12_-_96794143 0.17 ENST00000543119.2
 CDK17
 cyclin-dependent kinase 17
chr1_-_3566627 0.17 ENST00000419924.2
ENST00000270708.7
 WRAP73
 WD repeat containing, antisense to TP73
chr5_+_54455946 0.17 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
 GPX8
 glutathione peroxidase 8 (putative)
chr1_+_196788887 0.17 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
 CFHR1
CFHR2
 complement factor H-related 1
complement factor H-related 2
chr3_-_122283079 0.17 ENST00000471785.1
ENST00000466126.1
 PARP9
 poly (ADP-ribose) polymerase family, member 9
chr11_+_59807748 0.17 ENST00000278855.2
ENST00000532905.1
 PLAC1L
 oocyte secreted protein 2
chr2_+_161993465 0.16 ENST00000457476.1
 TANK
 TRAF family member-associated NFKB activator
chrX_+_36065053 0.16 ENST00000313548.4
 CHDC2
 calponin homology domain containing 2
chr2_-_65593784 0.16 ENST00000443619.2
 SPRED2
 sprouty-related, EVH1 domain containing 2
chr5_+_140810132 0.16 ENST00000252085.3
 PCDHGA12
 protocadherin gamma subfamily A, 12
chr3_-_178969403 0.16 ENST00000314235.5
ENST00000392685.2
 KCNMB3
 potassium large conductance calcium-activated channel, subfamily M beta member 3
chr12_-_91348949 0.16 ENST00000358859.2
 CCER1
 coiled-coil glutamate-rich protein 1
chr11_-_118213360 0.16 ENST00000529594.1
 CD3D
 CD3d molecule, delta (CD3-TCR complex)
chr19_-_14049184 0.16 ENST00000339560.5
 PODNL1
 podocan-like 1
chr6_+_29429217 0.16 ENST00000396792.2
 OR2H1
 olfactory receptor, family 2, subfamily H, member 1
chr6_-_79944336 0.16 ENST00000344726.5
ENST00000275036.7
 HMGN3
 high mobility group nucleosomal binding domain 3
chr2_+_106679690 0.16 ENST00000409944.1
 C2orf40
 chromosome 2 open reading frame 40
chr6_+_63921399 0.16 ENST00000356170.3
 FKBP1C
 FK506 binding protein 1C
chr15_+_25200074 0.16 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
 SNRPN
 small nuclear ribonucleoprotein polypeptide N
chr14_-_106471723 0.16 ENST00000390595.2
 IGHV1-3
 immunoglobulin heavy variable 1-3
chr13_+_21714653 0.16 ENST00000382533.4
 SAP18
 Sin3A-associated protein, 18kDa
chr19_-_54974894 0.16 ENST00000333834.4
 LENG9
 leukocyte receptor cluster (LRC) member 9
chr6_+_28249332 0.16 ENST00000259883.3
 PGBD1
 piggyBac transposable element derived 1
chr14_+_57671888 0.16 ENST00000391612.1
 AL391152.1
 AL391152.1
chr14_-_106586656 0.16 ENST00000390602.2
 IGHV3-13
 immunoglobulin heavy variable 3-13
chr20_+_56964169 0.16 ENST00000475243.1
 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
chr5_+_115420688 0.15 ENST00000274458.4
 COMMD10
 COMM domain containing 10
chr6_-_35765088 0.15 ENST00000259938.2
 CLPS
 colipase, pancreatic
chr19_+_38085731 0.15 ENST00000589117.1
 ZNF540
 zinc finger protein 540
chr8_-_7220490 0.15 ENST00000400078.2
 ZNF705G
 zinc finger protein 705G
chr1_-_148025848 0.15 ENST00000310701.10
ENST00000369219.1
ENST00000444640.1
ENST00000431121.1
ENST00000436356.1
ENST00000448574.1
ENST00000458135.1
ENST00000392972.3
ENST00000426874.1
 NBPF14
 neuroblastoma breakpoint family, member 14
chr14_+_52164820 0.15 ENST00000554167.1
 FRMD6
 FERM domain containing 6
chr3_-_3221358 0.15 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
 CRBN
 cereblon
chr6_+_127587755 0.15 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146
 ring finger protein 146
chrX_+_150866779 0.15 ENST00000370353.3
 PRRG3
 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chrX_-_19988382 0.15 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
 CXorf23
 chromosome X open reading frame 23
chr2_+_109204909 0.15 ENST00000393310.1
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr1_+_144151520 0.15 ENST00000369372.4
 NBPF8
 neuroblastoma breakpoint family, member 8
chr11_+_114166536 0.14 ENST00000299964.3
 NNMT
 nicotinamide N-methyltransferase
chr5_+_112073544 0.14 ENST00000257430.4
ENST00000508376.2
 APC
 adenomatous polyposis coli
chr7_-_80141328 0.14 ENST00000398291.3
 GNAT3
 guanine nucleotide binding protein, alpha transducing 3
chr1_+_145516560 0.14 ENST00000537888.1
 PEX11B
 peroxisomal biogenesis factor 11 beta
chr17_-_29641084 0.14 ENST00000544462.1
 EVI2B
 ecotropic viral integration site 2B
chr1_+_53480598 0.14 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
 SCP2
 sterol carrier protein 2
chr7_+_13141097 0.14 ENST00000411542.1
 AC011288.2
 AC011288.2
chr1_+_178310581 0.14 ENST00000462775.1
 RASAL2
 RAS protein activator like 2
chr19_-_20748541 0.14 ENST00000427401.4
ENST00000594419.1
 ZNF737
 zinc finger protein 737
chr3_-_149095652 0.14 ENST00000305366.3
 TM4SF1
 transmembrane 4 L six family member 1
chr9_-_135230336 0.14 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
 SETX
 senataxin
chr21_+_45553535 0.14 ENST00000348499.5
ENST00000389690.3
ENST00000449622.1
 C21orf33
 chromosome 21 open reading frame 33
chr13_+_100741269 0.14 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
 PCCA
 propionyl CoA carboxylase, alpha polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 1.7 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.2 0.7 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 0.5 GO:1990927 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.4 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.3 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 2.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:2000340 interleukin-15 production(GO:0032618) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.1 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.1 0.2 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.1 GO:0042100 B cell proliferation(GO:0042100)
0.0 1.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.2 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.0 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.0 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0044241 lipid digestion(GO:0044241)
0.0 0.4 GO:0001945 lymph vessel development(GO:0001945)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 0.8 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.0 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.1 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 8.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.4 GO:0005503 all-trans retinal binding(GO:0005503)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.5 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.0 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane