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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MAX_TFEB

Z-value: 0.29

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Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
MAX
ENSG00000125952.14 MAX
TFEB
ENSG00000112561.13 TFEB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAXhg19_v2_chr14_-_65569057_655691190.953.8e-04Click!
TFEBhg19_v2_chr6_-_41703296_417033670.705.5e-02Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_49458107 1.03 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
 BAX
 BCL2-associated X protein
chr10_-_93392811 0.80 ENST00000238994.5
 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
chr1_+_183605200 0.58 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr5_-_172198190 0.46 ENST00000239223.3
 DUSP1
 dual specificity phosphatase 1
chr22_+_35776828 0.45 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr15_+_44084040 0.45 ENST00000249786.4
 SERF2
 small EDRK-rich factor 2
chr15_+_44084503 0.39 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
 SERF2
 small EDRK-rich factor 2
chr1_+_221051699 0.38 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr12_-_76953453 0.37 ENST00000549570.1
 OSBPL8
 oxysterol binding protein-like 8
chr19_+_14544099 0.36 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
 PKN1
 protein kinase N1
chr12_+_56110247 0.36 ENST00000551926.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_56109810 0.35 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
 RP11-644F5.10
BLOC1S1
 Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr22_+_31003133 0.34 ENST00000405742.3
 TCN2
 transcobalamin II
chr9_-_79307096 0.31 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
 PRUNE2
 prune homolog 2 (Drosophila)
chr17_-_66951474 0.31 ENST00000269080.2
 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
chr22_+_31002779 0.31 ENST00000215838.3
 TCN2
 transcobalamin II
chr14_-_65569057 0.31 ENST00000555419.1
ENST00000341653.2
 MAX
 MYC associated factor X
chr14_-_65569244 0.30 ENST00000557277.1
ENST00000556892.1
 MAX
 MYC associated factor X
chr22_-_36903069 0.30 ENST00000216187.6
ENST00000423980.1
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr12_+_56109926 0.30 ENST00000547076.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chr5_-_133706695 0.29 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
 CDKL3
 cyclin-dependent kinase-like 3
chr19_-_48018203 0.28 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
chr11_+_64781575 0.28 ENST00000246747.4
ENST00000529384.1
 ARL2
 ADP-ribosylation factor-like 2
chr1_-_212873267 0.28 ENST00000243440.1
 BATF3
 basic leucine zipper transcription factor, ATF-like 3
chr2_+_148778570 0.27 ENST00000407073.1
 MBD5
 methyl-CpG binding domain protein 5
chr13_+_113951607 0.27 ENST00000397181.3
 LAMP1
 lysosomal-associated membrane protein 1
chr22_-_36903101 0.27 ENST00000397224.4
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chrX_+_30671476 0.26 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
 GK
 glycerol kinase
chr1_-_241520525 0.26 ENST00000366565.1
 RGS7
 regulator of G-protein signaling 7
chr17_-_7137582 0.25 ENST00000575756.1
ENST00000575458.1
 DVL2
 dishevelled segment polarity protein 2
chr7_+_99070527 0.25 ENST00000379724.3
 ZNF789
 zinc finger protein 789
chr1_-_241520385 0.25 ENST00000366564.1
 RGS7
 regulator of G-protein signaling 7
chr11_+_67776012 0.25 ENST00000539229.1
 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
chr4_-_100242549 0.25 ENST00000305046.8
ENST00000394887.3
 ADH1B
 alcohol dehydrogenase 1B (class I), beta polypeptide
chr12_-_76953513 0.25 ENST00000547540.1
 OSBPL8
 oxysterol binding protein-like 8
chr3_-_178789220 0.24 ENST00000414084.1
 ZMAT3
 zinc finger, matrin-type 3
chr16_-_4897266 0.23 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
 GLYR1
 glyoxylate reductase 1 homolog (Arabidopsis)
chrX_+_102883887 0.23 ENST00000372625.3
ENST00000372624.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr11_+_64781657 0.22 ENST00000533729.1
 ARL2
 ADP-ribosylation factor-like 2
chr1_+_151171012 0.22 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
 PIP5K1A
 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr22_-_20850128 0.21 ENST00000328879.4
 KLHL22
 kelch-like family member 22
chr8_+_104383728 0.21 ENST00000330295.5
 CTHRC1
 collagen triple helix repeat containing 1
chr5_+_133706865 0.21 ENST00000265339.2
 UBE2B
 ubiquitin-conjugating enzyme E2B
chr12_+_117176113 0.20 ENST00000319176.7
 RNFT2
 ring finger protein, transmembrane 2
chr21_-_38639601 0.20 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
 DSCR3
 Down syndrome critical region gene 3
chr19_-_12833361 0.20 ENST00000592287.1
 TNPO2
 transportin 2
chr1_-_51425902 0.20 ENST00000396153.2
 FAF1
 Fas (TNFRSF6) associated factor 1
chr7_+_150065879 0.20 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
 REPIN1
ZNF775
 replication initiator 1
zinc finger protein 775
chr16_+_85061367 0.19 ENST00000538274.1
ENST00000258180.3
 KIAA0513
 KIAA0513
chr12_-_58146048 0.19 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
 CDK4
 cyclin-dependent kinase 4
chrX_-_102531717 0.19 ENST00000372680.1
 TCEAL5
 transcription elongation factor A (SII)-like 5
chr22_-_36902522 0.18 ENST00000397223.4
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr15_+_33022885 0.18 ENST00000322805.4
 GREM1
 gremlin 1, DAN family BMP antagonist
chrX_+_102883620 0.18 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr14_-_35183755 0.18 ENST00000555765.1
 CFL2
 cofilin 2 (muscle)
chr2_+_46926048 0.17 ENST00000306503.5
 SOCS5
 suppressor of cytokine signaling 5
chr2_+_30370382 0.17 ENST00000402708.1
 YPEL5
 yippee-like 5 (Drosophila)
chr5_-_121413974 0.17 ENST00000231004.4
 LOX
 lysyl oxidase
chr20_+_37590942 0.17 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
 DHX35
 DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr1_+_11866207 0.17 ENST00000312413.6
ENST00000346436.6
 CLCN6
 chloride channel, voltage-sensitive 6
chr19_+_39903185 0.17 ENST00000409794.3
 PLEKHG2
 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr22_-_20850070 0.17 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
 KLHL22
 kelch-like family member 22
chr15_-_83316087 0.17 ENST00000568757.1
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr7_+_100464760 0.17 ENST00000200457.4
 TRIP6
 thyroid hormone receptor interactor 6
chrX_-_102510045 0.16 ENST00000360000.4
 TCEAL8
 transcription elongation factor A (SII)-like 8
chr7_+_99746514 0.16 ENST00000341942.5
ENST00000441173.1
 LAMTOR4
 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chrX_-_102510126 0.16 ENST00000372685.3
 TCEAL8
 transcription elongation factor A (SII)-like 8
chr17_-_37886752 0.16 ENST00000577810.1
 MIEN1
 migration and invasion enhancer 1
chr22_-_24622080 0.16 ENST00000425408.1
 GGT5
 gamma-glutamyltransferase 5
chr5_-_176730676 0.16 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
 RAB24
 RAB24, member RAS oncogene family
chr1_-_31845914 0.16 ENST00000373713.2
 FABP3
 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chrX_+_102631248 0.16 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr14_-_20923195 0.16 ENST00000206542.4
 OSGEP
 O-sialoglycoprotein endopeptidase
chr14_-_20929624 0.16 ENST00000398020.4
ENST00000250489.4
 TMEM55B
 transmembrane protein 55B
chrX_+_55744166 0.15 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chr12_-_58146128 0.15 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
 CDK4
 cyclin-dependent kinase 4
chr5_-_139944196 0.15 ENST00000357560.4
 APBB3
 amyloid beta (A4) precursor protein-binding, family B, member 3
chrX_+_108780347 0.15 ENST00000372103.1
 NXT2
 nuclear transport factor 2-like export factor 2
chr7_+_150065278 0.15 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
 REPIN1
 replication initiator 1
chr6_+_127588020 0.15 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
 RNF146
 ring finger protein 146
chr17_-_66453562 0.15 ENST00000262139.5
ENST00000546360.1
 WIPI1
 WD repeat domain, phosphoinositide interacting 1
chr1_+_159750776 0.14 ENST00000368107.1
 DUSP23
 dual specificity phosphatase 23
chr14_+_96505659 0.14 ENST00000555004.1
 C14orf132
 chromosome 14 open reading frame 132
chr1_-_28969517 0.14 ENST00000263974.4
ENST00000373824.4
 TAF12
 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr21_-_35987438 0.14 ENST00000313806.4
 RCAN1
 regulator of calcineurin 1
chrX_+_102840408 0.14 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
 TCEAL4
 transcription elongation factor A (SII)-like 4
chrX_+_55744228 0.14 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chrX_+_102631844 0.14 ENST00000372634.1
ENST00000299872.7
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr20_-_2821271 0.14 ENST00000448755.1
ENST00000360652.2
 PCED1A
 PC-esterase domain containing 1A
chr1_+_33116765 0.14 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
 RBBP4
 retinoblastoma binding protein 4
chr6_+_127587755 0.14 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146
 ring finger protein 146
chr2_+_27805880 0.14 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
 ZNF512
 zinc finger protein 512
chr8_-_13134045 0.14 ENST00000512044.2
 DLC1
 deleted in liver cancer 1
chr14_+_77564440 0.14 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
 KIAA1737
 CLOCK-interacting pacemaker
chr1_-_28559502 0.14 ENST00000263697.4
 DNAJC8
 DnaJ (Hsp40) homolog, subfamily C, member 8
chrX_+_108779870 0.14 ENST00000372107.1
 NXT2
 nuclear transport factor 2-like export factor 2
chr14_-_65569186 0.14 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
 MAX
 MYC associated factor X
chr6_-_33385823 0.14 ENST00000494751.1
ENST00000374496.3
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr21_-_46237883 0.14 ENST00000397893.3
 SUMO3
 small ubiquitin-like modifier 3
chr1_+_159750720 0.14 ENST00000368109.1
ENST00000368108.3
 DUSP23
 dual specificity phosphatase 23
chr10_-_49860525 0.13 ENST00000435790.2
 ARHGAP22
 Rho GTPase activating protein 22
chr1_-_202896310 0.13 ENST00000367261.3
 KLHL12
 kelch-like family member 12
chr12_+_6833237 0.13 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
 COPS7A
 COP9 signalosome subunit 7A
chr2_-_211036051 0.13 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
 KANSL1L
 KAT8 regulatory NSL complex subunit 1-like
chr17_-_57184260 0.13 ENST00000376149.3
ENST00000393066.3
 TRIM37
 tripartite motif containing 37
chr12_-_76953573 0.13 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
 OSBPL8
 oxysterol binding protein-like 8
chr3_-_49395705 0.13 ENST00000419349.1
 GPX1
 glutathione peroxidase 1
chr5_+_156712372 0.13 ENST00000541131.1
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr14_-_74551096 0.13 ENST00000350259.4
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr12_-_63328817 0.13 ENST00000228705.6
 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_+_54332535 0.13 ENST00000243056.3
 HOXC13
 homeobox C13
chr6_-_33385902 0.13 ENST00000374500.5
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr9_+_74526532 0.13 ENST00000486911.2
 C9orf85
 chromosome 9 open reading frame 85
chr11_+_120894781 0.12 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
 TBCEL
 tubulin folding cofactor E-like
chr2_+_201170703 0.12 ENST00000358677.5
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr12_+_90102729 0.12 ENST00000605386.1
 LINC00936
 long intergenic non-protein coding RNA 936
chr20_+_48552908 0.12 ENST00000244061.2
 RNF114
 ring finger protein 114
chr15_+_41913690 0.12 ENST00000563576.1
 MGA
 MGA, MAX dimerization protein
chrX_-_34675391 0.12 ENST00000275954.3
 TMEM47
 transmembrane protein 47
chr5_-_139943830 0.12 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
 APBB3
 amyloid beta (A4) precursor protein-binding, family B, member 3
chr17_+_42977122 0.12 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
 FAM187A
CCDC103
 family with sequence similarity 187, member A
coiled-coil domain containing 103
chr19_+_50016610 0.12 ENST00000596975.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr20_-_443129 0.12 ENST00000354200.4
 TBC1D20
 TBC1 domain family, member 20
chr2_+_46926326 0.12 ENST00000394861.2
 SOCS5
 suppressor of cytokine signaling 5
chr1_-_222885770 0.12 ENST00000355727.2
ENST00000340020.6
 AIDA
 axin interactor, dorsalization associated
chr7_+_100271446 0.12 ENST00000419828.1
ENST00000427895.1
 GNB2
 guanine nucleotide binding protein (G protein), beta polypeptide 2
chr7_+_100271355 0.12 ENST00000436220.1
ENST00000424361.1
 GNB2
 guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_+_50016411 0.12 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr6_+_42018614 0.12 ENST00000465926.1
ENST00000482432.1
 TAF8
 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr17_+_57408994 0.12 ENST00000312655.4
 YPEL2
 yippee-like 2 (Drosophila)
chr8_+_42128812 0.12 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
 IKBKB
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr3_-_49395892 0.12 ENST00000419783.1
 GPX1
 glutathione peroxidase 1
chr21_+_38445539 0.12 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
 TTC3
 tetratricopeptide repeat domain 3
chr19_-_36545128 0.12 ENST00000538849.1
 THAP8
 THAP domain containing 8
chr7_-_56118981 0.12 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
 PSPH
 phosphoserine phosphatase
chr14_+_24630465 0.12 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
 IRF9
 interferon regulatory factor 9
chr20_-_34638841 0.11 ENST00000565493.1
 LINC00657
 long intergenic non-protein coding RNA 657
chr22_+_31003190 0.11 ENST00000407817.3
 TCN2
 transcobalamin II
chr6_-_43197189 0.11 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
 DNPH1
 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr12_+_51633061 0.11 ENST00000551313.1
 DAZAP2
 DAZ associated protein 2
chr1_+_52521957 0.11 ENST00000472944.2
ENST00000484036.1
 BTF3L4
 basic transcription factor 3-like 4
chr6_-_33385870 0.11 ENST00000488034.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr7_-_56119156 0.11 ENST00000421312.1
ENST00000416592.1
 PSPH
 phosphoserine phosphatase
chr21_-_38639813 0.11 ENST00000309117.6
ENST00000398998.1
 DSCR3
 Down syndrome critical region gene 3
chr4_+_76439665 0.11 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
 THAP6
 THAP domain containing 6
chr6_+_7590413 0.11 ENST00000342415.5
 SNRNP48
 small nuclear ribonucleoprotein 48kDa (U11/U12)
chr1_+_145611010 0.11 ENST00000369291.5
 RNF115
 ring finger protein 115
chr6_-_33385854 0.11 ENST00000488478.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr19_-_45681482 0.11 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
 TRAPPC6A
 trafficking protein particle complex 6A
chr22_-_50700140 0.11 ENST00000215659.8
 MAPK12
 mitogen-activated protein kinase 12
chr20_-_2821756 0.11 ENST00000356872.3
ENST00000439542.1
 PCED1A
 PC-esterase domain containing 1A
chr12_+_56110315 0.11 ENST00000548556.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chrX_-_101397433 0.11 ENST00000372774.3
 TCEAL6
 transcription elongation factor A (SII)-like 6
chr2_-_27545921 0.11 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
 MPV17
 MpV17 mitochondrial inner membrane protein
chr15_-_65281775 0.11 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
 SPG21
 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr21_-_46238034 0.11 ENST00000332859.6
 SUMO3
 small ubiquitin-like modifier 3
chr6_+_158589374 0.11 ENST00000607778.1
 GTF2H5
 general transcription factor IIH, polypeptide 5
chr10_+_99258625 0.11 ENST00000370664.3
 UBTD1
 ubiquitin domain containing 1
chrX_+_101380642 0.11 ENST00000372780.1
ENST00000329035.2
 TCEAL2
 transcription elongation factor A (SII)-like 2
chr5_+_126112794 0.11 ENST00000261366.5
ENST00000395354.1
 LMNB1
 lamin B1
chr1_+_52521797 0.11 ENST00000313334.8
 BTF3L4
 basic transcription factor 3-like 4
chr19_-_8386238 0.11 ENST00000301457.2
 NDUFA7
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr8_-_95961578 0.11 ENST00000448464.2
ENST00000342697.4
 TP53INP1
 tumor protein p53 inducible nuclear protein 1
chr7_-_2354099 0.11 ENST00000222990.3
 SNX8
 sorting nexin 8
chr2_-_131099897 0.11 ENST00000409127.1
ENST00000437688.2
ENST00000259229.2
 CCDC115
 coiled-coil domain containing 115
chr16_-_20367584 0.10 ENST00000570689.1
 UMOD
 uromodulin
chrX_-_15872914 0.10 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
 AP1S2
 adaptor-related protein complex 1, sigma 2 subunit
chr21_-_46237959 0.10 ENST00000397898.3
ENST00000411651.2
 SUMO3
 small ubiquitin-like modifier 3
chr10_-_31320840 0.10 ENST00000375311.1
 ZNF438
 zinc finger protein 438
chr5_+_43603229 0.10 ENST00000344920.4
ENST00000512996.2
 NNT
 nicotinamide nucleotide transhydrogenase
chr6_-_41888843 0.10 ENST00000434077.1
ENST00000409312.1
 MED20
 mediator complex subunit 20
chr6_-_33385655 0.10 ENST00000440279.3
ENST00000607266.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr15_-_40213080 0.10 ENST00000561100.1
 GPR176
 G protein-coupled receptor 176
chr1_-_51425772 0.10 ENST00000371778.4
 FAF1
 Fas (TNFRSF6) associated factor 1
chr3_-_127541679 0.10 ENST00000265052.5
 MGLL
 monoglyceride lipase
chr12_+_117176090 0.10 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
 RNFT2
 ring finger protein, transmembrane 2
chr1_-_26233423 0.10 ENST00000357865.2
 STMN1
 stathmin 1
chr16_-_15736953 0.10 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
 KIAA0430
 KIAA0430
chrX_-_100872911 0.10 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6
 armadillo repeat containing, X-linked 6
chr17_-_7137857 0.10 ENST00000005340.5
 DVL2
 dishevelled segment polarity protein 2
chr14_-_54955721 0.10 ENST00000554908.1
 GMFB
 glia maturation factor, beta
chr15_-_50978965 0.10 ENST00000560955.1
ENST00000313478.7
 TRPM7
 transient receptor potential cation channel, subfamily M, member 7
chr1_+_52521928 0.10 ENST00000489308.2
 BTF3L4
 basic transcription factor 3-like 4
chr9_+_133320301 0.10 ENST00000352480.5
 ASS1
 argininosuccinate synthase 1
chr11_-_58611957 0.10 ENST00000532258.1
 GLYATL2
 glycine-N-acyltransferase-like 2
chr3_+_19988885 0.10 ENST00000422242.1
 RAB5A
 RAB5A, member RAS oncogene family
chr12_+_7023735 0.10 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
 ENO2
 enolase 2 (gamma, neuronal)
chr14_-_74551172 0.10 ENST00000553458.1
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr1_-_183604794 0.10 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
 ARPC5
 actin related protein 2/3 complex, subunit 5, 16kDa
chr7_-_27183263 0.10 ENST00000222726.3
 HOXA5
 homeobox A5
chr20_+_43595115 0.10 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
 STK4
 serine/threonine kinase 4
chr5_-_68628543 0.10 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
 CCDC125
 coiled-coil domain containing 125
chr20_-_30458019 0.10 ENST00000486996.1
ENST00000398084.2
 DUSP15
 dual specificity phosphatase 15
chr19_-_5340730 0.10 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
 PTPRS
 protein tyrosine phosphatase, receptor type, S
chr12_+_72148614 0.10 ENST00000261263.3
 RAB21
 RAB21, member RAS oncogene family
chr1_-_154909329 0.10 ENST00000368467.3
 PMVK
 phosphomevalonate kinase
chr11_+_65479702 0.09 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
 KAT5
 K(lysine) acetyltransferase 5
chr1_-_3447967 0.09 ENST00000294599.4
 MEGF6
 multiple EGF-like-domains 6
chr7_-_6312206 0.09 ENST00000350796.3
 CYTH3
 cytohesin 3
chr12_+_71833756 0.09 ENST00000536515.1
ENST00000540815.2
 LGR5
 leucine-rich repeat containing G protein-coupled receptor 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1903519 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2 0.5 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.8 GO:0015889 cobalamin transport(GO:0015889)
0.1 1.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.2 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.0 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0061110 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.0 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.0 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.0 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0031751 D2 dopamine receptor binding(GO:0031749) D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.0 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.0 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.0 GO:0019203 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443) carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.1 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling