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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MEF2B

Z-value: 0.56

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
MEF2B
ENSG00000213999.11 MEF2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg19_v2_chr19_-_19302931_19302974-0.849.7e-03Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_58251716 0.96 ENST00000355648.4
 PHACTR3
 phosphatase and actin regulator 3
chr1_+_77333117 0.81 ENST00000477717.1
 ST6GALNAC5
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr15_+_40531243 0.71 ENST00000558055.1
ENST00000455577.2
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_1860200 0.70 ENST00000381911.1
 TNNI2
 troponin I type 2 (skeletal, fast)
chr15_+_40531621 0.68 ENST00000560346.1
 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_1860682 0.63 ENST00000381906.1
 TNNI2
 troponin I type 2 (skeletal, fast)
chr11_+_1860832 0.62 ENST00000252898.7
 TNNI2
 troponin I type 2 (skeletal, fast)
chr12_+_44229846 0.59 ENST00000551577.1
ENST00000266534.3
 TMEM117
 transmembrane protein 117
chr2_-_165424973 0.55 ENST00000543549.1
 GRB14
 growth factor receptor-bound protein 14
chr7_-_16872932 0.53 ENST00000419572.2
ENST00000412973.1
 AGR2
 anterior gradient 2
chr21_-_42219065 0.52 ENST00000400454.1
 DSCAM
 Down syndrome cell adhesion molecule
chr5_-_16509101 0.49 ENST00000399793.2
 FAM134B
 family with sequence similarity 134, member B
chr3_+_186739636 0.44 ENST00000440338.1
ENST00000448044.1
 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr4_-_143227088 0.42 ENST00000511838.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_143226979 0.39 ENST00000514525.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_-_116311402 0.39 ENST00000261448.5
 CASQ2
 calsequestrin 2 (cardiac muscle)
chr4_-_25865159 0.38 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
 SEL1L3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_-_208030647 0.35 ENST00000309446.6
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr1_+_212782012 0.34 ENST00000341491.4
ENST00000366985.1
 ATF3
 activating transcription factor 3
chr14_+_76776957 0.34 ENST00000512784.1
 ESRRB
 estrogen-related receptor beta
chr1_-_204329013 0.32 ENST00000272203.3
ENST00000414478.1
 PLEKHA6
 pleckstrin homology domain containing, family A member 6
chr14_-_22005343 0.32 ENST00000327430.3
 SALL2
 spalt-like transcription factor 2
chr16_+_84328429 0.31 ENST00000568638.1
 WFDC1
 WAP four-disulfide core domain 1
chr16_+_84328252 0.31 ENST00000219454.5
 WFDC1
 WAP four-disulfide core domain 1
chr14_-_21493884 0.29 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
 NDRG2
 NDRG family member 2
chr17_-_9694614 0.29 ENST00000330255.5
ENST00000571134.1
 DHRS7C
 dehydrogenase/reductase (SDR family) member 7C
chr3_+_127634069 0.28 ENST00000405109.1
 KBTBD12
 kelch repeat and BTB (POZ) domain containing 12
chr3_+_127634312 0.27 ENST00000407609.3
 KBTBD12
 kelch repeat and BTB (POZ) domain containing 12
chr12_+_52445191 0.26 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
 NR4A1
 nuclear receptor subfamily 4, group A, member 1
chr4_-_143767428 0.25 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_+_1993173 0.24 ENST00000523438.1
 MYOM2
 myomesin 2
chr7_-_105332084 0.23 ENST00000472195.1
 ATXN7L1
 ataxin 7-like 1
chr11_+_7597639 0.23 ENST00000533792.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_84630367 0.23 ENST00000370680.1
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr8_+_1993152 0.22 ENST00000262113.4
 MYOM2
 myomesin 2
chr10_+_71561649 0.22 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
 COL13A1
 collagen, type XIII, alpha 1
chr6_+_44194762 0.22 ENST00000371708.1
 SLC29A1
 solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_92632542 0.21 ENST00000409154.4
ENST00000370378.4
 KIAA1107
 KIAA1107
chr14_-_21493123 0.21 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
 NDRG2
 NDRG family member 2
chr10_+_71561630 0.21 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
 COL13A1
 collagen, type XIII, alpha 1
chr2_-_208031542 0.21 ENST00000423015.1
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr16_-_88717482 0.18 ENST00000261623.3
 CYBA
 cytochrome b-245, alpha polypeptide
chr14_-_21493649 0.17 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
 NDRG2
 NDRG family member 2
chr16_-_88717423 0.17 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
 CYBA
 cytochrome b-245, alpha polypeptide
chr6_+_12007897 0.17 ENST00000437559.1
 RP11-456H18.2
 RP11-456H18.2
chr10_-_69455873 0.15 ENST00000433211.2
 CTNNA3
 catenin (cadherin-associated protein), alpha 3
chr1_+_145413268 0.15 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
 HFE2
 hemochromatosis type 2 (juvenile)
chrX_-_63450480 0.14 ENST00000362002.2
 ASB12
 ankyrin repeat and SOCS box containing 12
chr6_-_137314371 0.14 ENST00000432330.1
ENST00000418699.1
 RP11-55K22.5
 RP11-55K22.5
chr8_+_107282368 0.13 ENST00000521369.2
 RP11-395G23.3
 RP11-395G23.3
chr1_-_156460391 0.13 ENST00000360595.3
 MEF2D
 myocyte enhancer factor 2D
chr1_-_26394114 0.13 ENST00000374272.3
 TRIM63
 tripartite motif containing 63, E3 ubiquitin protein ligase
chr6_+_12007963 0.13 ENST00000607445.1
 RP11-456H18.2
 RP11-456H18.2
chr3_-_52486841 0.12 ENST00000496590.1
 TNNC1
 troponin C type 1 (slow)
chr9_-_74980113 0.12 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
 ZFAND5
 zinc finger, AN1-type domain 5
chr7_-_37488834 0.12 ENST00000310758.4
 ELMO1
 engulfment and cell motility 1
chr19_-_16008880 0.12 ENST00000011989.7
ENST00000221700.6
 CYP4F2
 cytochrome P450, family 4, subfamily F, polypeptide 2
chr14_+_56046914 0.11 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
 KTN1
 kinectin 1 (kinesin receptor)
chr16_+_12058961 0.11 ENST00000053243.1
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr17_-_48785216 0.11 ENST00000285243.6
 ANKRD40
 ankyrin repeat domain 40
chr4_+_8321882 0.10 ENST00000509453.1
ENST00000503186.1
 RP11-774O3.2
RP11-774O3.1
 RP11-774O3.2
RP11-774O3.1
chr10_+_71561704 0.10 ENST00000520267.1
 COL13A1
 collagen, type XIII, alpha 1
chr8_-_27115931 0.10 ENST00000523048.1
 STMN4
 stathmin-like 4
chr10_+_135340859 0.10 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
 CYP2E1
 cytochrome P450, family 2, subfamily E, polypeptide 1
chr12_+_25205446 0.10 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
 LRMP
 lymphoid-restricted membrane protein
chr3_+_35683651 0.10 ENST00000187397.4
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chrX_-_11284095 0.10 ENST00000303025.6
ENST00000534860.1
 ARHGAP6
 Rho GTPase activating protein 6
chr11_-_84634447 0.10 ENST00000532653.1
 DLG2
 discs, large homolog 2 (Drosophila)
chr12_-_99548270 0.09 ENST00000546568.1
ENST00000332712.7
ENST00000546960.1
 ANKS1B
 ankyrin repeat and sterile alpha motif domain containing 1B
chr5_+_132009675 0.09 ENST00000231449.2
ENST00000350025.2
 IL4
 interleukin 4
chr16_+_12059050 0.09 ENST00000396495.3
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr14_+_56046990 0.09 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
 KTN1
 kinectin 1 (kinesin receptor)
chr11_-_47400062 0.09 ENST00000533030.1
 SPI1
 spleen focus forming virus (SFFV) proviral integration oncogene
chr6_+_152128371 0.09 ENST00000443427.1
 ESR1
 estrogen receptor 1
chr18_-_35145728 0.08 ENST00000361795.5
ENST00000603232.1
 CELF4
 CUGBP, Elav-like family member 4
chr7_-_121944491 0.08 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
 FEZF1
 FEZ family zinc finger 1
chr8_+_107282389 0.08 ENST00000577661.1
ENST00000445937.1
 RP11-395G23.3
OXR1
 RP11-395G23.3
oxidation resistance 1
chr17_-_42200958 0.08 ENST00000336057.5
 HDAC5
 histone deacetylase 5
chr3_+_188664988 0.07 ENST00000433971.1
 TPRG1
 tumor protein p63 regulated 1
chr12_-_131200810 0.07 ENST00000536002.1
ENST00000544034.1
 RIMBP2
RP11-662M24.2
 RIMS binding protein 2
RP11-662M24.2
chr4_+_41362796 0.07 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
 LIMCH1
 LIM and calponin homology domains 1
chr3_+_46924829 0.07 ENST00000313049.5
 PTH1R
 parathyroid hormone 1 receptor
chr11_-_84634217 0.07 ENST00000524982.1
 DLG2
 discs, large homolog 2 (Drosophila)
chr17_+_20059302 0.07 ENST00000395530.2
 SPECC1
 sperm antigen with calponin homology and coiled-coil domains 1
chr3_-_11610255 0.07 ENST00000424529.2
 VGLL4
 vestigial like 4 (Drosophila)
chr17_-_34417479 0.06 ENST00000225245.5
 CCL3
 chemokine (C-C motif) ligand 3
chr12_-_7899935 0.06 ENST00000543765.1
 CLEC4C
 C-type lectin domain family 4, member C
chr1_+_22778337 0.06 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
 ZBTB40
 zinc finger and BTB domain containing 40
chr19_+_16607122 0.06 ENST00000221671.3
ENST00000594035.1
ENST00000599550.1
ENST00000594813.1
 C19orf44
 chromosome 19 open reading frame 44
chr16_-_31439735 0.06 ENST00000287490.4
 COX6A2
 cytochrome c oxidase subunit VIa polypeptide 2
chr17_-_42200996 0.06 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
 HDAC5
 histone deacetylase 5
chr20_+_44035847 0.06 ENST00000372712.2
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr10_-_96829246 0.05 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
 CYP2C8
 cytochrome P450, family 2, subfamily C, polypeptide 8
chr6_-_123957942 0.05 ENST00000398178.3
 TRDN
 triadin
chr6_+_50061315 0.05 ENST00000415106.1
 RP11-397G17.1
 RP11-397G17.1
chr4_+_44680429 0.05 ENST00000281543.5
 GUF1
 GUF1 GTPase homolog (S. cerevisiae)
chr11_-_19223523 0.05 ENST00000265968.3
 CSRP3
 cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr12_-_111358372 0.05 ENST00000548438.1
ENST00000228841.8
 MYL2
 myosin, light chain 2, regulatory, cardiac, slow
chr6_+_42984723 0.05 ENST00000332245.8
 KLHDC3
 kelch domain containing 3
chr5_-_131347306 0.05 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chr9_+_116327326 0.05 ENST00000342620.5
 RGS3
 regulator of G-protein signaling 3
chr2_+_88367299 0.05 ENST00000419482.2
ENST00000444564.2
 SMYD1
 SET and MYND domain containing 1
chr2_+_168043793 0.05 ENST00000409273.1
ENST00000409605.1
 XIRP2
 xin actin-binding repeat containing 2
chr8_-_27115903 0.05 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
 STMN4
 stathmin-like 4
chr8_+_76452097 0.04 ENST00000396423.2
 HNF4G
 hepatocyte nuclear factor 4, gamma
chr20_+_61147651 0.04 ENST00000370527.3
ENST00000370524.2
 C20orf166
 chromosome 20 open reading frame 166
chr6_+_152128686 0.04 ENST00000206249.3
 ESR1
 estrogen receptor 1
chr12_+_25205666 0.04 ENST00000547044.1
 LRMP
 lymphoid-restricted membrane protein
chr18_-_35145981 0.04 ENST00000420428.2
ENST00000412753.1
 CELF4
 CUGBP, Elav-like family member 4
chr14_+_39735411 0.04 ENST00000603904.1
 RP11-407N17.3
 cTAGE family member 5 isoform 4
chr12_-_371994 0.03 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
 SLC6A13
 solute carrier family 6 (neurotransmitter transporter), member 13
chr8_+_95565947 0.03 ENST00000523011.1
 RP11-267M23.4
 RP11-267M23.4
chr15_+_40226304 0.03 ENST00000559624.1
ENST00000382727.2
ENST00000263791.5
ENST00000560648.1
 EIF2AK4
 eukaryotic translation initiation factor 2 alpha kinase 4
chr3_-_113897545 0.03 ENST00000467632.1
 DRD3
 dopamine receptor D3
chr15_+_42651691 0.03 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
 CAPN3
 calpain 3, (p94)
chr2_-_157198860 0.03 ENST00000409572.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr8_-_95565673 0.03 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
 KIAA1429
 KIAA1429
chr21_-_33984456 0.03 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
 AP000275.65
C21orf59
 Uncharacterized protein
chromosome 21 open reading frame 59
chr3_+_49057876 0.03 ENST00000326912.4
 NDUFAF3
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr20_+_44657845 0.03 ENST00000243964.3
 SLC12A5
 solute carrier family 12 (potassium/chloride transporter), member 5
chr12_+_25205568 0.03 ENST00000548766.1
ENST00000556887.1
 LRMP
 lymphoid-restricted membrane protein
chr12_-_7899958 0.03 ENST00000360345.3
 CLEC4C
 C-type lectin domain family 4, member C
chr18_+_3252206 0.02 ENST00000578562.2
 MYL12A
 myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_26348259 0.02 ENST00000374280.3
 EXTL1
 exostosin-like glycosyltransferase 1
chr18_+_12407895 0.02 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
 SLMO1
 slowmo homolog 1 (Drosophila)
chr17_-_5322786 0.02 ENST00000225696.4
 NUP88
 nucleoporin 88kDa
chr11_-_47399942 0.02 ENST00000227163.4
 SPI1
 spleen focus forming virus (SFFV) proviral integration oncogene
chr20_+_10199468 0.02 ENST00000254976.2
ENST00000304886.2
 SNAP25
 synaptosomal-associated protein, 25kDa
chr18_-_47792851 0.02 ENST00000398545.4
 CCDC11
 coiled-coil domain containing 11
chr17_+_7184986 0.02 ENST00000317370.8
ENST00000571308.1
 SLC2A4
 solute carrier family 2 (facilitated glucose transporter), member 4
chr10_-_97200772 0.02 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
 SORBS1
 sorbin and SH3 domain containing 1
chr7_-_113559104 0.01 ENST00000284601.3
 PPP1R3A
 protein phosphatase 1, regulatory subunit 3A
chr10_-_75415825 0.01 ENST00000394810.2
 SYNPO2L
 synaptopodin 2-like
chr20_-_54580523 0.01 ENST00000064571.2
 CBLN4
 cerebellin 4 precursor
chr13_+_39261224 0.01 ENST00000280481.7
 FREM2
 FRAS1 related extracellular matrix protein 2
chr11_+_75110530 0.01 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
 RPS3
 ribosomal protein S3
chr12_-_49393092 0.01 ENST00000421952.2
 DDN
 dendrin
chr2_+_220299547 0.00 ENST00000312358.7
 SPEG
 SPEG complex locus
chr19_-_51220176 0.00 ENST00000359082.3
ENST00000293441.1
 SHANK1
 SH3 and multiple ankyrin repeat domains 1
chr7_+_143013198 0.00 ENST00000343257.2
 CLCN1
 chloride channel, voltage-sensitive 1
chr3_-_57326704 0.00 ENST00000487349.1
ENST00000389601.3
 ASB14
 ankyrin repeat and SOCS box containing 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 1.3 GO:0097503 sialylation(GO:0097503)
0.0 0.4 GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:1903781 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of cardiac conduction(GO:1903781)
0.0 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.7 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 2.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 2.1 GO:0031014 troponin T binding(GO:0031014)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation