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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MEF2D_MEF2A

Z-value: 0.50

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Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
MEF2D
ENSG00000116604.13 MEF2D
MEF2A
ENSG00000068305.13 MEF2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Ahg19_v2_chr15_+_100106244_1001062920.658.1e-02Click!
MEF2Dhg19_v2_chr1_-_156460391_156460417-0.413.1e-01Click!

Activity profile of MEF2D_MEF2A motif

Sorted Z-values of MEF2D_MEF2A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_111091948 1.91 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr3_+_99357319 1.04 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
 COL8A1
 collagen, type VIII, alpha 1
chr5_-_150521192 0.96 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr2_-_190044480 0.82 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr12_-_91539918 0.73 ENST00000548218.1
 DCN
 decorin
chr1_+_221051699 0.71 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr1_+_170633047 0.68 ENST00000239461.6
ENST00000497230.2
 PRRX1
 paired related homeobox 1
chrX_-_142722897 0.63 ENST00000338017.4
 SLITRK4
 SLIT and NTRK-like family, member 4
chr6_-_154751629 0.57 ENST00000424998.1
 CNKSR3
 CNKSR family member 3
chr13_-_67802549 0.55 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr1_+_114522049 0.49 ENST00000369551.1
ENST00000320334.4
 OLFML3
 olfactomedin-like 3
chr4_+_55095264 0.48 ENST00000257290.5
 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
chr2_+_233497931 0.45 ENST00000264059.3
 EFHD1
 EF-hand domain family, member D1
chr1_+_145524891 0.43 ENST00000369304.3
 ITGA10
 integrin, alpha 10
chr6_+_136172820 0.42 ENST00000308191.6
 PDE7B
 phosphodiesterase 7B
chr5_+_173316341 0.37 ENST00000520867.1
ENST00000334035.5
 CPEB4
 cytoplasmic polyadenylation element binding protein 4
chr3_-_112360116 0.36 ENST00000206423.3
ENST00000439685.2
 CCDC80
 coiled-coil domain containing 80
chr6_+_132129151 0.36 ENST00000360971.2
 ENPP1
 ectonucleotide pyrophosphatase/phosphodiesterase 1
chr13_+_76378305 0.36 ENST00000526371.1
ENST00000526528.1
 LMO7
 LIM domain 7
chr13_+_76210448 0.36 ENST00000377499.5
 LMO7
 LIM domain 7
chr5_+_67584174 0.34 ENST00000320694.8
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_39640513 0.34 ENST00000511809.1
ENST00000505729.1
 SMIM14
 small integral membrane protein 14
chr13_+_76378357 0.32 ENST00000489941.2
ENST00000525373.1
 LMO7
 LIM domain 7
chr13_+_76334498 0.32 ENST00000534657.1
 LMO7
 LIM domain 7
chr1_-_31845914 0.28 ENST00000373713.2
 FABP3
 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_-_57547454 0.28 ENST00000556376.2
 HOPX
 HOP homeobox
chr4_-_57547870 0.28 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
 HOPX
 HOP homeobox
chr3_+_69928256 0.28 ENST00000394355.2
 MITF
 microphthalmia-associated transcription factor
chr1_-_153518270 0.27 ENST00000354332.4
ENST00000368716.4
 S100A4
 S100 calcium binding protein A4
chr2_+_148778570 0.27 ENST00000407073.1
 MBD5
 methyl-CpG binding domain protein 5
chr17_+_37821593 0.27 ENST00000578283.1
 TCAP
 titin-cap
chr17_+_68165657 0.27 ENST00000243457.3
 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
chr10_-_62704005 0.27 ENST00000337910.5
 RHOBTB1
 Rho-related BTB domain containing 1
chrX_-_21776281 0.26 ENST00000379494.3
 SMPX
 small muscle protein, X-linked
chr11_-_19223523 0.26 ENST00000265968.3
 CSRP3
 cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr7_+_120629653 0.26 ENST00000450913.2
ENST00000340646.5
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr3_+_69812877 0.25 ENST00000457080.1
ENST00000328528.6
 MITF
 microphthalmia-associated transcription factor
chr1_+_156095951 0.24 ENST00000448611.2
ENST00000368297.1
 LMNA
 lamin A/C
chr8_+_27183033 0.24 ENST00000420218.2
 PTK2B
 protein tyrosine kinase 2 beta
chr10_+_104178946 0.24 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr8_+_27182862 0.24 ENST00000521164.1
ENST00000346049.5
 PTK2B
 protein tyrosine kinase 2 beta
chr6_+_108977520 0.23 ENST00000540898.1
 FOXO3
 forkhead box O3
chr2_-_211168332 0.22 ENST00000341685.4
 MYL1
 myosin, light chain 1, alkali; skeletal, fast
chr13_+_76334795 0.21 ENST00000526202.1
ENST00000465261.2
 LMO7
 LIM domain 7
chr4_+_113970772 0.20 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
 ANK2
 ankyrin 2, neuronal
chr4_+_129730839 0.20 ENST00000511647.1
 PHF17
 jade family PHD finger 1
chr17_-_1389228 0.19 ENST00000438665.2
 MYO1C
 myosin IC
chr17_+_42248063 0.19 ENST00000293414.1
 ASB16
 ankyrin repeat and SOCS box containing 16
chr17_-_1389419 0.19 ENST00000575158.1
 MYO1C
 myosin IC
chr1_+_201617450 0.19 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
 NAV1
 neuron navigator 1
chr1_+_171060018 0.19 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
 FMO3
 flavin containing monooxygenase 3
chr3_+_8543393 0.19 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
 LMCD1
 LIM and cysteine-rich domains 1
chr7_-_134143841 0.19 ENST00000285930.4
 AKR1B1
 aldo-keto reductase family 1, member B1 (aldose reductase)
chr19_+_35630344 0.18 ENST00000455515.2
 FXYD1
 FXYD domain containing ion transport regulator 1
chr4_+_129730779 0.18 ENST00000226319.6
 PHF17
 jade family PHD finger 1
chr13_+_76334567 0.18 ENST00000321797.8
 LMO7
 LIM domain 7
chr10_-_49860525 0.18 ENST00000435790.2
 ARHGAP22
 Rho GTPase activating protein 22
chr1_+_201617264 0.18 ENST00000367296.4
 NAV1
 neuron navigator 1
chr3_+_141106458 0.17 ENST00000509883.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr2_-_106054952 0.16 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
 FHL2
 four and a half LIM domains 2
chr11_+_65266507 0.16 ENST00000544868.1
 MALAT1
 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr1_-_206945830 0.15 ENST00000423557.1
 IL10
 interleukin 10
chr3_-_39234074 0.15 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
 XIRP1
 xin actin-binding repeat containing 1
chr2_+_220143989 0.15 ENST00000336576.5
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr3_+_8543561 0.15 ENST00000397386.3
 LMCD1
 LIM and cysteine-rich domains 1
chr8_-_13372253 0.15 ENST00000316609.5
 DLC1
 deleted in liver cancer 1
chr3_-_176914238 0.15 ENST00000430069.1
ENST00000428970.1
 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
chr4_-_186696425 0.14 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr15_-_83474806 0.14 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
 FSD2
 fibronectin type III and SPRY domain containing 2
chr15_+_100106155 0.14 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
 MEF2A
 myocyte enhancer factor 2A
chr3_+_141106643 0.14 ENST00000514251.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr6_-_41703952 0.14 ENST00000358871.2
ENST00000403298.4
 TFEB
 transcription factor EB
chr2_+_220144052 0.14 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr1_+_156096336 0.14 ENST00000504687.1
ENST00000473598.2
 LMNA
 lamin A/C
chr15_+_100106126 0.14 ENST00000558812.1
ENST00000338042.6
 MEF2A
 myocyte enhancer factor 2A
chr15_+_100106244 0.14 ENST00000557942.1
 MEF2A
 myocyte enhancer factor 2A
chr17_-_79900255 0.13 ENST00000330655.3
ENST00000582198.1
 MYADML2
PYCR1
 myeloid-associated differentiation marker-like 2
pyrroline-5-carboxylate reductase 1
chr19_+_37096194 0.13 ENST00000460670.1
ENST00000292928.2
ENST00000439428.1
 ZNF382
 zinc finger protein 382
chr2_+_161993465 0.13 ENST00000457476.1
 TANK
 TRAF family member-associated NFKB activator
chr3_+_8543533 0.12 ENST00000454244.1
 LMCD1
 LIM and cysteine-rich domains 1
chr3_-_137834436 0.12 ENST00000327532.2
ENST00000467030.1
 DZIP1L
 DAZ interacting zinc finger protein 1-like
chr7_-_150946015 0.12 ENST00000262188.8
 SMARCD3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_+_150245177 0.12 ENST00000369098.3
 C1orf54
 chromosome 1 open reading frame 54
chr1_-_46642154 0.12 ENST00000540385.1
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr21_+_17909594 0.12 ENST00000441820.1
ENST00000602280.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr3_+_179370517 0.12 ENST00000263966.3
 USP13
 ubiquitin specific peptidase 13 (isopeptidase T-3)
chrX_-_15332665 0.12 ENST00000537676.1
ENST00000344384.4
 ASB11
 ankyrin repeat and SOCS box containing 11
chr4_+_37892682 0.11 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_-_114343039 0.11 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr12_+_12938541 0.11 ENST00000356591.4
 APOLD1
 apolipoprotein L domain containing 1
chr8_-_27850141 0.11 ENST00000524352.1
 SCARA5
 scavenger receptor class A, member 5 (putative)
chr3_+_138067314 0.11 ENST00000423968.2
 MRAS
 muscle RAS oncogene homolog
chr15_-_52944231 0.11 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr9_+_127054217 0.11 ENST00000394199.2
ENST00000546191.1
 NEK6
 NIMA-related kinase 6
chr8_-_13372395 0.11 ENST00000276297.4
ENST00000511869.1
 DLC1
 deleted in liver cancer 1
chr4_+_120056939 0.11 ENST00000307128.5
 MYOZ2
 myozenin 2
chr9_-_85882145 0.11 ENST00000328788.1
 FRMD3
 FERM domain containing 3
chr5_-_66492562 0.11 ENST00000256447.4
 CD180
 CD180 molecule
chr11_+_12766583 0.11 ENST00000361985.2
 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_-_114682224 0.11 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
chr1_-_59249732 0.11 ENST00000371222.2
 JUN
 jun proto-oncogene
chr5_+_138609782 0.11 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
 MATR3
 matrin 3
chr10_-_3827371 0.10 ENST00000469435.1
 KLF6
 Kruppel-like factor 6
chr19_-_49926698 0.10 ENST00000270631.1
 PTH2
 parathyroid hormone 2
chr1_+_150245099 0.10 ENST00000369099.3
 C1orf54
 chromosome 1 open reading frame 54
chr2_-_211179883 0.10 ENST00000352451.3
 MYL1
 myosin, light chain 1, alkali; skeletal, fast
chr3_+_138067666 0.10 ENST00000475711.1
ENST00000464896.1
 MRAS
 muscle RAS oncogene homolog
chr2_+_161993412 0.10 ENST00000259075.2
ENST00000432002.1
 TANK
 TRAF family member-associated NFKB activator
chr1_+_84630645 0.10 ENST00000394839.2
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr21_-_35016231 0.10 ENST00000438788.1
 CRYZL1
 crystallin, zeta (quinone reductase)-like 1
chr2_+_44502597 0.10 ENST00000260649.6
ENST00000409387.1
 SLC3A1
 solute carrier family 3 (amino acid transporter heavy chain), member 1
chr17_-_42200996 0.10 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
 HDAC5
 histone deacetylase 5
chr11_+_57308979 0.10 ENST00000457912.1
 SMTNL1
 smoothelin-like 1
chr2_-_166060571 0.10 ENST00000360093.3
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr3_+_50316458 0.10 ENST00000316436.3
 LSMEM2
 leucine-rich single-pass membrane protein 2
chr16_-_15736881 0.10 ENST00000540441.2
 KIAA0430
 KIAA0430
chr16_-_15736953 0.10 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
 KIAA0430
 KIAA0430
chr2_+_42721689 0.10 ENST00000405592.1
 MTA3
 metastasis associated 1 family, member 3
chr3_-_145878954 0.09 ENST00000282903.5
ENST00000360060.3
 PLOD2
 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr14_-_89021077 0.09 ENST00000556564.1
 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
chr12_+_15699286 0.09 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr9_+_139871948 0.09 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
 PTGDS
 prostaglandin D2 synthase 21kDa (brain)
chr8_-_62602327 0.09 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
 ASPH
 aspartate beta-hydroxylase
chr1_+_160051319 0.09 ENST00000368088.3
 KCNJ9
 potassium inwardly-rectifying channel, subfamily J, member 9
chr11_+_45918092 0.09 ENST00000395629.2
 MAPK8IP1
 mitogen-activated protein kinase 8 interacting protein 1
chr15_+_93443419 0.09 ENST00000557381.1
ENST00000420239.2
 CHD2
 chromodomain helicase DNA binding protein 2
chr22_+_32340481 0.09 ENST00000397492.1
 YWHAH
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr19_+_35629702 0.09 ENST00000351325.4
 FXYD1
 FXYD domain containing ion transport regulator 1
chr4_-_186697044 0.09 ENST00000437304.2
 SORBS2
 sorbin and SH3 domain containing 2
chr2_-_166060552 0.09 ENST00000283254.7
ENST00000453007.1
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr8_-_72268889 0.09 ENST00000388742.4
 EYA1
 eyes absent homolog 1 (Drosophila)
chr2_+_11864458 0.09 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
 LPIN1
 lipin 1
chr17_+_6918064 0.09 ENST00000546760.1
ENST00000552402.1
 C17orf49
 chromosome 17 open reading frame 49
chr11_+_12399071 0.09 ENST00000539723.1
ENST00000550549.1
 PARVA
 parvin, alpha
chr9_-_215744 0.08 ENST00000382387.2
 C9orf66
 chromosome 9 open reading frame 66
chr17_+_7461613 0.08 ENST00000438470.1
ENST00000436057.1
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chr1_+_151129135 0.08 ENST00000602841.1
 SCNM1
 sodium channel modifier 1
chr14_-_70546897 0.08 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
 SLC8A3
 solute carrier family 8 (sodium/calcium exchanger), member 3
chr10_-_3827417 0.08 ENST00000497571.1
ENST00000542957.1
 KLF6
 Kruppel-like factor 6
chr17_-_42200958 0.08 ENST00000336057.5
 HDAC5
 histone deacetylase 5
chr4_+_119809984 0.08 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
 SYNPO2
 synaptopodin 2
chr9_-_130639997 0.08 ENST00000373176.1
 AK1
 adenylate kinase 1
chr7_+_30951461 0.08 ENST00000311813.4
 AQP1
 aquaporin 1 (Colton blood group)
chr3_+_54157480 0.08 ENST00000490478.1
 CACNA2D3
 calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr2_+_162087577 0.08 ENST00000439442.1
 TANK
 TRAF family member-associated NFKB activator
chr1_+_90098606 0.08 ENST00000370454.4
 LRRC8C
 leucine rich repeat containing 8 family, member C
chr8_-_72268968 0.08 ENST00000388740.3
 EYA1
 eyes absent homolog 1 (Drosophila)
chr19_+_35630022 0.08 ENST00000589209.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr17_+_6918093 0.07 ENST00000439424.2
 C17orf49
 chromosome 17 open reading frame 49
chr18_-_3219847 0.07 ENST00000261606.7
 MYOM1
 myomesin 1
chr22_-_36013368 0.07 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
 MB
 myoglobin
chr15_-_37391507 0.07 ENST00000557796.2
ENST00000397620.2
 MEIS2
 Meis homeobox 2
chr2_+_33661382 0.07 ENST00000402538.3
 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr22_+_25595817 0.07 ENST00000215855.2
ENST00000404334.1
 CRYBB3
 crystallin, beta B3
chr5_+_161274685 0.07 ENST00000428797.2
 GABRA1
 gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_-_47934234 0.07 ENST00000420772.2
 MAP4
 microtubule-associated protein 4
chr5_-_137475071 0.07 ENST00000265191.2
 NME5
 NME/NM23 family member 5
chr11_-_18034701 0.07 ENST00000265965.5
 SERGEF
 secretion regulating guanine nucleotide exchange factor
chr2_+_85766280 0.07 ENST00000306434.3
 MAT2A
 methionine adenosyltransferase II, alpha
chrX_+_18725758 0.07 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
 PPEF1
 protein phosphatase, EF-hand calcium binding domain 1
chr10_+_88428206 0.07 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
 LDB3
 LIM domain binding 3
chr9_-_97356075 0.07 ENST00000375337.3
 FBP2
 fructose-1,6-bisphosphatase 2
chr7_-_27169801 0.07 ENST00000511914.1
 HOXA4
 homeobox A4
chr22_-_31742218 0.07 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
 PATZ1
 POZ (BTB) and AT hook containing zinc finger 1
chr1_-_201391149 0.07 ENST00000555948.1
ENST00000556362.1
 TNNI1
 troponin I type 1 (skeletal, slow)
chr7_+_18535346 0.07 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
 HDAC9
 histone deacetylase 9
chr8_-_70745575 0.07 ENST00000524945.1
 SLCO5A1
 solute carrier organic anion transporter family, member 5A1
chr1_-_150693318 0.07 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
 HORMAD1
 HORMA domain containing 1
chr17_+_80186908 0.06 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
 SLC16A3
 solute carrier family 16 (monocarboxylate transporter), member 3
chr18_-_77276057 0.06 ENST00000597412.1
 AC018445.1
 Uncharacterized protein
chr19_+_50832943 0.06 ENST00000542413.1
 NR1H2
 nuclear receptor subfamily 1, group H, member 2
chr15_-_37391614 0.06 ENST00000219869.9
 MEIS2
 Meis homeobox 2
chr16_+_31225337 0.06 ENST00000322122.3
 TRIM72
 tripartite motif containing 72
chr22_-_51016846 0.06 ENST00000312108.7
ENST00000395650.2
 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
chr10_+_88428370 0.06 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
 LDB3
 LIM domain binding 3
chr9_+_129677123 0.06 ENST00000373436.1
 RALGPS1
 Ral GEF with PH domain and SH3 binding motif 1
chr19_-_893200 0.06 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
 MED16
 mediator complex subunit 16
chr1_+_156211753 0.06 ENST00000368272.4
 BGLAP
 bone gamma-carboxyglutamate (gla) protein
chr8_-_7309887 0.06 ENST00000458665.1
ENST00000528168.1
 SPAG11B
 sperm associated antigen 11B
chr2_+_168043793 0.06 ENST00000409273.1
ENST00000409605.1
 XIRP2
 xin actin-binding repeat containing 2
chr11_-_88796803 0.06 ENST00000418177.2
ENST00000455756.2
 GRM5
 glutamate receptor, metabotropic 5
chr13_+_76378407 0.06 ENST00000447038.1
 LMO7
 LIM domain 7
chr1_-_159825137 0.06 ENST00000368102.1
 C1orf204
 chromosome 1 open reading frame 204
chr16_+_30075463 0.06 ENST00000562168.1
ENST00000569545.1
 ALDOA
 aldolase A, fructose-bisphosphate
chrX_-_30327495 0.05 ENST00000453287.1
 NR0B1
 nuclear receptor subfamily 0, group B, member 1
chr19_-_40324255 0.05 ENST00000593685.1
ENST00000600611.1
 DYRK1B
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr1_+_182584314 0.05 ENST00000566297.1
 RP11-317P15.4
 RP11-317P15.4
chr7_-_27702455 0.05 ENST00000265395.2
 HIBADH
 3-hydroxyisobutyrate dehydrogenase
chr12_-_49393092 0.05 ENST00000421952.2
 DDN
 dendrin
chr5_-_131347501 0.05 ENST00000543479.1
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chrX_-_70288234 0.05 ENST00000276105.3
ENST00000374274.3
 SNX12
 sorting nexin 12
chr4_-_83765613 0.05 ENST00000503937.1
 SEC31A
 SEC31 homolog A (S. cerevisiae)
chr22_+_32340447 0.05 ENST00000248975.5
 YWHAH
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr13_+_51483814 0.05 ENST00000336617.3
ENST00000422660.1
 RNASEH2B
 ribonuclease H2, subunit B
chrX_-_71933888 0.05 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
 PHKA1
 phosphorylase kinase, alpha 1 (muscle)
chr10_-_104178857 0.05 ENST00000020673.5
 PSD
 pleckstrin and Sec7 domain containing
chr3_+_138067521 0.05 ENST00000494949.1
 MRAS
 muscle RAS oncogene homolog
chr5_-_141030943 0.05 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
 FCHSD1
 FCH and double SH3 domains 1
chr16_+_15737124 0.05 ENST00000396355.1
ENST00000396353.2
 NDE1
 nudE neurodevelopment protein 1
chr6_-_169654139 0.05 ENST00000366787.3
 THBS2
 thrombospondin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.4 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059) inner medullary collecting duct development(GO:0072061)
0.1 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.1 0.3 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 1.0 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic recombination checkpoint(GO:0051598)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.0 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.0 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.0 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 1.0 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.0 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 1.0 GO:0044291 cell-cell contact zone(GO:0044291)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0034191 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.0 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets