Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
MESP1 Links Ensembl NCBI GeneCards UniProt	ENSG00000166823.5	MESP1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MESP1	hg19_v2_chr15_-_90294523_90294541	-0.92	1.0e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr1_+_60280458	1.31	ENST00000455990.1 ENST00000371208.3	HOOK1	hook microtubule-tethering protein 1
chr17_-_39274606	1.15	ENST00000391413.2	KRTAP4-11	keratin associated protein 4-11
chr1_-_209979465	0.92	ENST00000542854.1	IRF6	interferon regulatory factor 6
chr2_+_47596287	0.92	ENST00000263735.4	EPCAM	epithelial cell adhesion molecule
chr13_-_20806440	0.80	ENST00000400066.3 ENST00000400065.3 ENST00000356192.6	GJB6	gap junction protein, beta 6, 30kDa
chr16_+_68679193	0.80	ENST00000581171.1	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr17_+_39382900	0.75	ENST00000377721.3 ENST00000455970.2	KRTAP9-2	keratin associated protein 9-2
chr1_-_160990886	0.71	ENST00000537746.1	F11R	F11 receptor
chr1_-_209979375	0.66	ENST00000367021.3	IRF6	interferon regulatory factor 6
chr4_+_40198527	0.63	ENST00000381799.5	RHOH	ras homolog family member H
chr11_-_108464465	0.63	ENST00000525344.1	EXPH5	exophilin 5
chr19_+_35739597	0.61	ENST00000361790.3	LSR	lipolysis stimulated lipoprotein receptor
chr19_+_35739631	0.61	ENST00000602003.1 ENST00000360798.3 ENST00000354900.3	LSR	lipolysis stimulated lipoprotein receptor
chr19_+_35739782	0.61	ENST00000347609.4	LSR	lipolysis stimulated lipoprotein receptor
chr8_+_120220561	0.61	ENST00000276681.6	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr16_+_68771128	0.60	ENST00000261769.5 ENST00000422392.2	CDH1	cadherin 1, type 1, E-cadherin (epithelial)
chr16_+_68678739	0.59	ENST00000264012.4	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr11_-_108464321	0.58	ENST00000265843.4	EXPH5	exophilin 5
chr18_+_47088401	0.58	ENST00000261292.4 ENST00000427224.2 ENST00000580036.1	LIPG	lipase, endothelial
chr17_-_39674668	0.57	ENST00000393981.3	KRT15	keratin 15
chr1_+_183155373	0.56	ENST00000493293.1 ENST00000264144.4	LAMC2	laminin, gamma 2
chr1_+_44399466	0.56	ENST00000498139.2 ENST00000491846.1	ARTN	artemin
chr16_+_68678892	0.55	ENST00000429102.2	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr7_+_16793160	0.53	ENST00000262067.4	TSPAN13	tetraspanin 13
chr1_+_2005425	0.53	ENST00000461106.2	PRKCZ	protein kinase C, zeta
chr19_+_35739280	0.53	ENST00000602122.1	LSR	lipolysis stimulated lipoprotein receptor
chr12_+_41086297	0.51	ENST00000551295.2	CNTN1	contactin 1
chr17_-_7165662	0.51	ENST00000571881.2 ENST00000360325.7	CLDN7	claudin 7
chr13_-_20767037	0.51	ENST00000382848.4	GJB2	gap junction protein, beta 2, 26kDa
chr17_+_9548845	0.49	ENST00000570475.1 ENST00000285199.7	USP43	ubiquitin specific peptidase 43
chr15_+_41136586	0.49	ENST00000431806.1	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr1_+_109792641	0.49	ENST00000271332.3	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2
chr6_+_150464155	0.48	ENST00000361131.4	PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr19_-_51456198	0.47	ENST00000594846.1	KLK5	kallikrein-related peptidase 5
chr19_+_38755203	0.47	ENST00000587090.1 ENST00000454580.3	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr3_-_111314230	0.47	ENST00000317012.4	ZBED2	zinc finger, BED-type containing 2
chr8_+_102504651	0.46	ENST00000251808.3 ENST00000521085.1	GRHL2	grainyhead-like 2 (Drosophila)
chr1_+_24646002	0.45	ENST00000356046.2	GRHL3	grainyhead-like 3 (Drosophila)
chr1_+_24645807	0.44	ENST00000361548.4	GRHL3	grainyhead-like 3 (Drosophila)
chr19_-_35992780	0.44	ENST00000593342.1 ENST00000601650.1 ENST00000408915.2	DMKN	dermokine
chr1_+_24645865	0.44	ENST00000342072.4	GRHL3	grainyhead-like 3 (Drosophila)
chr17_-_7493390	0.44	ENST00000538513.2 ENST00000570788.1 ENST00000250055.2	SOX15	SRY (sex determining region Y)-box 15
chr6_+_7541808	0.43	ENST00000379802.3	DSP	desmoplakin
chr19_+_38755042	0.42	ENST00000301244.7	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr6_+_7541845	0.42	ENST00000418664.2	DSP	desmoplakin
chr5_+_68788594	0.41	ENST00000396442.2 ENST00000380766.2	OCLN	occludin
chr8_+_32405785	0.41	ENST00000287842.3	NRG1	neuregulin 1
chr11_+_1860200	0.41	ENST00000381911.1	TNNI2	troponin I type 2 (skeletal, fast)
chr2_-_238499303	0.41	ENST00000409576.1	RAB17	RAB17, member RAS oncogene family
chr7_+_26331541	0.40	ENST00000416246.1 ENST00000338523.4 ENST00000412416.1	SNX10	sorting nexin 10
chr8_+_32405728	0.40	ENST00000523079.1 ENST00000338921.4 ENST00000356819.4 ENST00000287845.5 ENST00000341377.5	NRG1	neuregulin 1
chr3_-_190040223	0.39	ENST00000295522.3	CLDN1	claudin 1
chr12_+_53342625	0.39	ENST00000388837.2 ENST00000550600.1 ENST00000388835.3	KRT18	keratin 18
chr4_-_6202247	0.38	ENST00000409021.3 ENST00000409371.3	JAKMIP1	janus kinase and microtubule interacting protein 1
chr1_+_1981890	0.37	ENST00000378567.3 ENST00000468310.1	PRKCZ	protein kinase C, zeta
chr1_+_95582881	0.37	ENST00000370203.4 ENST00000456991.1	TMEM56	transmembrane protein 56
chr2_+_120770686	0.37	ENST00000331393.4 ENST00000443124.1	EPB41L5	erythrocyte membrane protein band 4.1 like 5
chr6_+_36098262	0.37	ENST00000373761.6 ENST00000373766.5	MAPK13	mitogen-activated protein kinase 13
chr8_-_127570603	0.36	ENST00000304916.3	FAM84B	family with sequence similarity 84, member B
chr19_-_51471362	0.35	ENST00000376853.4 ENST00000424910.2	KLK6	kallikrein-related peptidase 6
chr1_+_95286151	0.35	ENST00000467909.1 ENST00000422520.2 ENST00000532427.1	SLC44A3	solute carrier family 44, member 3
chrX_-_102565932	0.35	ENST00000372674.1 ENST00000372677.3	BEX2	brain expressed X-linked 2
chr17_-_39324424	0.35	ENST00000391356.2	KRTAP4-3	keratin associated protein 4-3
chr19_+_6464243	0.35	ENST00000600229.1 ENST00000356762.3	CRB3	crumbs homolog 3 (Drosophila)
chr18_+_29077990	0.35	ENST00000261590.8	DSG2	desmoglein 2
chr3_-_133748913	0.34	ENST00000310926.4	SLCO2A1	solute carrier organic anion transporter family, member 2A1
chr1_+_186798073	0.34	ENST00000367466.3 ENST00000442353.2	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr11_+_1855645	0.34	ENST00000381968.3 ENST00000381978.3	SYT8	synaptotagmin VIII
chr19_-_51471381	0.34	ENST00000594641.1	KLK6	kallikrein-related peptidase 6
chr17_+_80693427	0.33	ENST00000300784.7	FN3K	fructosamine 3 kinase
chr19_-_49565254	0.33	ENST00000593537.1	NTF4	neurotrophin 4
chr18_-_47721447	0.32	ENST00000285039.7	MYO5B	myosin VB
chr1_+_95285896	0.32	ENST00000446120.2 ENST00000271227.6 ENST00000527077.1 ENST00000529450.1	SLC44A3	solute carrier family 44, member 3
chr1_+_13910479	0.32	ENST00000509009.1	PDPN	podoplanin
chr19_+_6464502	0.32	ENST00000308243.7	CRB3	crumbs homolog 3 (Drosophila)
chr16_-_4987065	0.31	ENST00000590782.2 ENST00000345988.2	PPL	periplakin
chr17_+_73521763	0.31	ENST00000167462.5 ENST00000375227.4 ENST00000392550.3 ENST00000578363.1 ENST00000579392.1	LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr11_+_1856034	0.31	ENST00000341958.3	SYT8	synaptotagmin VIII
chr4_+_48018781	0.31	ENST00000295461.5	NIPAL1	NIPA-like domain containing 1
chr12_-_53343602	0.30	ENST00000546897.1 ENST00000552551.1	KRT8	keratin 8
chr14_+_75746340	0.30	ENST00000555686.1 ENST00000555672.1	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr15_+_74833518	0.30	ENST00000346246.5	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr15_-_63674034	0.29	ENST00000344366.3 ENST00000422263.2	CA12	carbonic anhydrase XII
chr11_-_88070920	0.29	ENST00000524463.1 ENST00000227266.5	CTSC	cathepsin C
chr7_+_18535786	0.28	ENST00000406072.1	HDAC9	histone deacetylase 9
chr11_+_1860682	0.28	ENST00000381906.1	TNNI2	troponin I type 2 (skeletal, fast)
chr22_+_29876197	0.28	ENST00000310624.6	NEFH	neurofilament, heavy polypeptide
chr7_-_22396533	0.28	ENST00000344041.6	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr17_+_39394250	0.28	ENST00000254072.6	KRTAP9-8	keratin associated protein 9-8
chr11_+_1860832	0.28	ENST00000252898.7	TNNI2	troponin I type 2 (skeletal, fast)
chr19_+_751122	0.28	ENST00000215582.6	MISP	mitotic spindle positioning
chr11_-_118122996	0.27	ENST00000525386.1 ENST00000527472.1 ENST00000278949.4	MPZL3	myelin protein zero-like 3
chr9_-_126030817	0.27	ENST00000348403.5 ENST00000447404.2 ENST00000360998.3	STRBP	spermatid perinuclear RNA binding protein
chr1_-_55266926	0.27	ENST00000371276.4	TTC22	tetratricopeptide repeat domain 22
chr2_+_68961934	0.27	ENST00000409202.3	ARHGAP25	Rho GTPase activating protein 25
chr8_-_144655141	0.27	ENST00000398882.3	MROH6	maestro heat-like repeat family member 6
chr5_-_141257954	0.27	ENST00000456271.1 ENST00000394536.3 ENST00000503492.1 ENST00000287008.3	PCDH1	protocadherin 1
chr2_+_68961905	0.26	ENST00000295381.3	ARHGAP25	Rho GTPase activating protein 25
chr4_+_75310851	0.26	ENST00000395748.3 ENST00000264487.2	AREG	amphiregulin
chr2_-_238499725	0.26	ENST00000264601.3	RAB17	RAB17, member RAS oncogene family
chr20_-_23030296	0.26	ENST00000377103.2	THBD	thrombomodulin
chr19_+_7660716	0.26	ENST00000160298.4 ENST00000446248.2	CAMSAP3	calmodulin regulated spectrin-associated protein family, member 3
chr5_+_68711209	0.26	ENST00000512803.1	MARVELD2	MARVEL domain containing 2
chr19_-_51472823	0.26	ENST00000310157.2	KLK6	kallikrein-related peptidase 6
chr4_+_106816592	0.26	ENST00000379987.2 ENST00000453617.2 ENST00000427316.2 ENST00000514622.1 ENST00000305572.8	NPNT	nephronectin
chr12_+_56473628	0.26	ENST00000549282.1 ENST00000549061.1 ENST00000267101.3	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr17_-_39296739	0.25	ENST00000345847.4	KRTAP4-6	keratin associated protein 4-6
chr14_+_75746781	0.25	ENST00000555347.1	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr1_+_161676739	0.25	ENST00000236938.6 ENST00000367959.2 ENST00000546024.1 ENST00000540521.1 ENST00000367949.2 ENST00000350710.3 ENST00000540926.1	FCRLA	Fc receptor-like A
chr5_+_68710906	0.25	ENST00000325631.5 ENST00000454295.2	MARVELD2	MARVEL domain containing 2
chr4_+_75311019	0.25	ENST00000502307.1	AREG	amphiregulin
chr9_+_132099158	0.25	ENST00000444125.1	RP11-65J3.1	RP11-65J3.1
chr1_+_161676983	0.24	ENST00000367957.2	FCRLA	Fc receptor-like A
chr2_+_220492373	0.24	ENST00000317151.3	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr1_+_13910194	0.24	ENST00000376057.4 ENST00000510906.1	PDPN	podoplanin
chr1_+_161677034	0.24	ENST00000349527.4 ENST00000309691.6 ENST00000294796.4 ENST00000367953.3 ENST00000367950.1	FCRLA	Fc receptor-like A
chr15_-_63674218	0.24	ENST00000178638.3	CA12	carbonic anhydrase XII
chrX_-_153141302	0.24	ENST00000361699.4 ENST00000543994.1 ENST00000370057.3 ENST00000538883.1 ENST00000361981.3	L1CAM	L1 cell adhesion molecule
chr8_+_22438009	0.23	ENST00000409417.1	PDLIM2	PDZ and LIM domain 2 (mystique)
chr11_-_119991589	0.23	ENST00000526881.1	TRIM29	tripartite motif containing 29
chr3_+_32433154	0.23	ENST00000334983.5 ENST00000349718.4	CMTM7	CKLF-like MARVEL transmembrane domain containing 7
chrX_-_34150428	0.23	ENST00000346193.3	FAM47A	family with sequence similarity 47, member A
chr21_-_42219065	0.23	ENST00000400454.1	DSCAM	Down syndrome cell adhesion molecule
chrX_+_105969893	0.23	ENST00000255499.2	RNF128	ring finger protein 128, E3 ubiquitin protein ligase
chr3_+_32433363	0.23	ENST00000465248.1	CMTM7	CKLF-like MARVEL transmembrane domain containing 7
chr1_-_184943610	0.22	ENST00000367511.3	FAM129A	family with sequence similarity 129, member A
chr2_-_238499337	0.22	ENST00000411462.1 ENST00000409822.1	RAB17	RAB17, member RAS oncogene family
chr11_+_65779283	0.22	ENST00000312134.2	CST6	cystatin E/M
chr13_+_113656022	0.22	ENST00000423482.2	MCF2L	MCF.2 cell line derived transforming sequence-like
chr17_-_39280419	0.22	ENST00000394014.1	KRTAP4-12	keratin associated protein 4-12
chr11_-_115375107	0.22	ENST00000545380.1 ENST00000452722.3 ENST00000537058.1 ENST00000536727.1 ENST00000542447.2 ENST00000331581.6	CADM1	cell adhesion molecule 1
chr18_+_55888767	0.22	ENST00000431212.2 ENST00000586268.1 ENST00000587190.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr9_-_23821842	0.22	ENST00000544538.1	ELAVL2	ELAV like neuron-specific RNA binding protein 2
chr9_+_101569944	0.21	ENST00000375011.3	GALNT12	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr4_-_139163491	0.21	ENST00000280612.5	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr4_+_75480629	0.21	ENST00000380846.3	AREGB	amphiregulin B
chr2_-_238499131	0.21	ENST00000538644.1	RAB17	RAB17, member RAS oncogene family
chr7_+_128784712	0.21	ENST00000289407.4	TSPAN33	tetraspanin 33
chr7_-_138666053	0.21	ENST00000440172.1 ENST00000422774.1	KIAA1549	KIAA1549
chr14_+_65171315	0.21	ENST00000394691.1	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_+_122459757	0.20	ENST00000261822.4	BCL7A	B-cell CLL/lymphoma 7A
chr2_-_165477971	0.20	ENST00000446413.2	GRB14	growth factor receptor-bound protein 14
chr3_+_111717600	0.20	ENST00000273368.4	TAGLN3	transgelin 3
chr22_+_29469012	0.20	ENST00000400335.4 ENST00000400338.2	KREMEN1	kringle containing transmembrane protein 1
chr5_-_1295104	0.20	ENST00000334602.6 ENST00000508104.2 ENST00000310581.5 ENST00000296820.5	TERT	telomerase reverse transcriptase
chr2_-_160761179	0.20	ENST00000554112.1 ENST00000553424.1 ENST00000263636.4 ENST00000504764.1 ENST00000505052.1	LY75 LY75-CD302	lymphocyte antigen 75 LY75-CD302 readthrough
chr15_+_45722727	0.20	ENST00000396650.2 ENST00000558435.1 ENST00000344300.3	C15orf48	chromosome 15 open reading frame 48
chr17_-_27503770	0.20	ENST00000533112.1	MYO18A	myosin XVIIIA
chr13_-_52980263	0.20	ENST00000258613.4 ENST00000544466.1	THSD1	thrombospondin, type I, domain containing 1
chr14_-_106781017	0.19	ENST00000390612.2	IGHV4-28	immunoglobulin heavy variable 4-28
chr14_-_107170409	0.19	ENST00000390633.2	IGHV1-69	immunoglobulin heavy variable 1-69
chr4_-_6202291	0.19	ENST00000282924.5	JAKMIP1	janus kinase and microtubule interacting protein 1
chr1_-_156675368	0.18	ENST00000368222.3	CRABP2	cellular retinoic acid binding protein 2
chr5_-_54281407	0.18	ENST00000381403.4	ESM1	endothelial cell-specific molecule 1
chr3_-_48470838	0.18	ENST00000358459.4 ENST00000358536.4	PLXNB1	plexin B1
chr19_-_55660561	0.18	ENST00000587758.1 ENST00000356783.5 ENST00000291901.8 ENST00000588426.1 ENST00000588147.1 ENST00000536926.1 ENST00000588981.1	TNNT1	troponin T type 1 (skeletal, slow)
chr14_-_38064198	0.18	ENST00000250448.2	FOXA1	forkhead box A1
chr3_+_140770183	0.18	ENST00000310546.2	SPSB4	splA/ryanodine receptor domain and SOCS box containing 4
chr17_-_46507537	0.18	ENST00000336915.6	SKAP1	src kinase associated phosphoprotein 1
chr6_-_30712313	0.18	ENST00000376377.2 ENST00000259874.5	IER3	immediate early response 3
chr7_+_20370746	0.18	ENST00000222573.4	ITGB8	integrin, beta 8
chr22_-_37882395	0.18	ENST00000416983.3 ENST00000424765.2 ENST00000356998.3	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_-_17035943	0.18	ENST00000355661.3 ENST00000532079.1 ENST00000448080.2 ENST00000531066.1	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr11_-_119993979	0.18	ENST00000524816.3 ENST00000525327.1	TRIM29	tripartite motif containing 29
chr2_+_173292301	0.18	ENST00000264106.6 ENST00000375221.2 ENST00000343713.4	ITGA6	integrin, alpha 6
chr2_-_20425158	0.17	ENST00000381150.1	SDC1	syndecan 1
chr8_+_98881268	0.17	ENST00000254898.5 ENST00000524308.1 ENST00000522025.2	MATN2	matrilin 2
chr15_-_31283618	0.17	ENST00000563714.1	MTMR10	myotubularin related protein 10
chr12_-_6756559	0.17	ENST00000536350.1 ENST00000414226.2 ENST00000546114.1	ACRBP	acrosin binding protein
chr5_-_16936340	0.17	ENST00000507288.1 ENST00000513610.1	MYO10	myosin X
chr9_-_136024721	0.17	ENST00000393160.3	RALGDS	ral guanine nucleotide dissociation stimulator
chr11_-_44971702	0.17	ENST00000533940.1 ENST00000533937.1	TP53I11	tumor protein p53 inducible protein 11
chr4_-_25865159	0.17	ENST00000502949.1 ENST00000264868.5 ENST00000513691.1 ENST00000514872.1	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr5_-_54281491	0.17	ENST00000381405.4	ESM1	endothelial cell-specific molecule 1
chr14_+_67999999	0.17	ENST00000329153.5	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr20_+_49348081	0.17	ENST00000371610.2	PARD6B	par-6 family cell polarity regulator beta
chr2_+_173292390	0.17	ENST00000442250.1 ENST00000458358.1 ENST00000409080.1	ITGA6	integrin, alpha 6
chr12_-_6756609	0.17	ENST00000229243.2	ACRBP	acrosin binding protein
chr17_+_37894179	0.17	ENST00000577695.1 ENST00000309156.4 ENST00000309185.3	GRB7	growth factor receptor-bound protein 7
chr13_+_88324870	0.17	ENST00000325089.6	SLITRK5	SLIT and NTRK-like family, member 5
chr2_+_173292280	0.16	ENST00000264107.7	ITGA6	integrin, alpha 6
chr1_-_156675535	0.16	ENST00000368221.1	CRABP2	cellular retinoic acid binding protein 2
chr12_-_95044309	0.16	ENST00000261226.4	TMCC3	transmembrane and coiled-coil domain family 3
chr22_+_29469100	0.16	ENST00000327813.5 ENST00000407188.1	KREMEN1	kringle containing transmembrane protein 1
chr15_-_42186248	0.16	ENST00000320955.6	SPTBN5	spectrin, beta, non-erythrocytic 5
chr9_-_117880477	0.16	ENST00000534839.1 ENST00000340094.3 ENST00000535648.1 ENST00000346706.3 ENST00000345230.3 ENST00000350763.4	TNC	tenascin C
chr19_-_44174330	0.16	ENST00000340093.3	PLAUR	plasminogen activator, urokinase receptor
chr15_-_44487408	0.16	ENST00000402883.1 ENST00000417257.1	FRMD5	FERM domain containing 5
chr16_-_3086927	0.16	ENST00000572449.1	CCDC64B	coiled-coil domain containing 64B
chr17_+_73717407	0.16	ENST00000579662.1	ITGB4	integrin, beta 4
chr3_+_111717511	0.16	ENST00000478951.1 ENST00000393917.2	TAGLN3	transgelin 3
chr9_+_2622085	0.16	ENST00000382099.2	VLDLR	very low density lipoprotein receptor
chr16_+_23847267	0.16	ENST00000321728.7	PRKCB	protein kinase C, beta
chr2_-_75788038	0.15	ENST00000393913.3 ENST00000410113.1	EVA1A	eva-1 homolog A (C. elegans)
chr17_-_39254391	0.15	ENST00000333822.4	KRTAP4-8	keratin associated protein 4-8
chr19_+_39279838	0.15	ENST00000314980.4	LGALS7B	lectin, galactoside-binding, soluble, 7B
chr19_-_39264072	0.15	ENST00000599035.1 ENST00000378626.4	LGALS7	lectin, galactoside-binding, soluble, 7
chr9_-_5833027	0.15	ENST00000339450.5	ERMP1	endoplasmic reticulum metallopeptidase 1
chr16_+_4845379	0.15	ENST00000588606.1 ENST00000586005.1	SMIM22	small integral membrane protein 22
chr5_-_94620239	0.15	ENST00000515393.1	MCTP1	multiple C2 domains, transmembrane 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0051796	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.5	2.4	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.3	1.4	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2	1.1	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2	0.6	GO:0048627	myoblast development(GO:0048627)
0.2	0.6	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2	0.9	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2	0.5	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.1	0.6	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1	0.6	GO:0044752	response to human chorionic gonadotropin(GO:0044752)
0.1	0.4	GO:1903348	cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.1	0.4	GO:0043000	Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.1	0.9	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.1	1.1	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.8	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1	0.6	GO:0097021	Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1	0.3	GO:0048936	neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	0.4	GO:0007509	mesoderm migration involved in gastrulation(GO:0007509)
0.1	0.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.5	GO:0055064	chloride ion homeostasis(GO:0055064)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.5	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1	0.3	GO:0007402	ganglion mother cell fate determination(GO:0007402)
0.1	0.5	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1	0.3	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.1	0.2	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.1	1.4	GO:0090179	planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1	0.4	GO:1903575	cornified envelope assembly(GO:1903575)
0.1	0.4	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.3	GO:2000721	pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	0.6	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.2	GO:1900369	transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.1	0.2	GO:1903028	positive regulation of opsonization(GO:1903028)
0.1	0.3	GO:0015862	uridine transport(GO:0015862)
0.1	0.2	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1	0.9	GO:0035878	nail development(GO:0035878)
0.1	0.4	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.2	GO:0036371	protein localization to T-tubule(GO:0036371)
0.1	1.3	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.2	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.1	0.4	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1	0.2	GO:0045226	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1	0.4	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	1.5	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0	0.1	GO:1903572	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0	0.2	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.1	GO:0044771	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.7	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.0	0.7	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.9	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.3	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0	0.1	GO:0072156	distal tubule morphogenesis(GO:0072156)
0.0	0.2	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.0	0.0	GO:0072244	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell development(GO:0072015) glomerular visceral epithelial cell differentiation(GO:0072112) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) glomerular epithelial cell development(GO:0072310) glomerular epithelial cell differentiation(GO:0072311) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0	0.3	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:1904862	inhibitory synapse assembly(GO:1904862)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.5	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0030311	poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.0	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
0.0	0.1	GO:0035284	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:2001302	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0	0.2	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	0.4	GO:0070673	response to interleukin-18(GO:0070673)
0.0	0.1	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.2	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.2	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0	0.6	GO:0045056	transcytosis(GO:0045056)
0.0	1.3	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.1	GO:1901594	detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.1	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0	0.1	GO:0007113	endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0	0.1	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0	0.3	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.3	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0090156	cellular sphingolipid homeostasis(GO:0090156)
0.0	0.3	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0035106	operant conditioning(GO:0035106)
0.0	0.2	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.1	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0009624	response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.1	GO:0002325	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0	0.0	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	0.0	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.0	GO:0010157	response to chlorate(GO:0010157)
0.0	3.0	GO:0031424	keratinization(GO:0031424)
0.0	1.4	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.2	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.2	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0051758	homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0	1.1	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0	0.1	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.0	GO:0035544	negative regulation of SNARE complex assembly(GO:0035544)
0.0	0.0	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0	0.1	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.0	0.1	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0	0.1	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0019348	dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009) G-quadruplex DNA unwinding(GO:0044806)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0035962	response to interleukin-13(GO:0035962)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.7	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.2	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.0	0.3	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.0	GO:0007398	ectoderm development(GO:0007398)
0.0	0.1	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0	0.3	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	0.0	GO:0050773	regulation of dendrite development(GO:0050773)
0.0	0.1	GO:0050976	sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.9	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.2	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.0	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.1	GO:0097319	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.0	GO:0052151	positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.2	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0	0.0	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0	0.1	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.0	GO:2000078	glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0	0.0	GO:0051892	negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0	0.1	GO:1901374	acetate ester transport(GO:1901374)
0.0	0.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.8	GO:0061689	tricellular tight junction(GO:0061689)
0.2	0.6	GO:0005607	laminin-2 complex(GO:0005607)
0.2	1.3	GO:0070695	FHF complex(GO:0070695)
0.2	0.5	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
0.1	1.2	GO:0045179	apical cortex(GO:0045179)
0.1	0.8	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1	0.8	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	0.2	GO:0031379	RNA-directed RNA polymerase complex(GO:0031379)
0.1	0.1	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.1	0.2	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.9	GO:0005916	fascia adherens(GO:0005916)
0.1	1.8	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.1	0.2	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	1.2	GO:0005922	connexon complex(GO:0005922)
0.1	0.4	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.1	0.4	GO:0035976	AP1 complex(GO:0035976)
0.0	1.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.5	GO:0005915	zonula adherens(GO:0005915)
0.0	3.0	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.0	2.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0032433	filopodium tip(GO:0032433)
0.0	2.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0	0.4	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.8	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.0	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.0	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0	0.6	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.8	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.0	GO:0034657	GID complex(GO:0034657)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.4	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	0.3	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.1	1.2	GO:0031014	troponin T binding(GO:0031014)
0.1	0.8	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	1.0	GO:0038132	neuregulin binding(GO:0038132)
0.1	0.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.2	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.1	1.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	0.2	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.2	GO:0034189	very-low-density lipoprotein particle binding(GO:0034189)
0.1	1.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.2	GO:0097363	protein O-GlcNAc transferase activity(GO:0097363)
0.0	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.6	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.9	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.9	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.4	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.0	0.1	GO:0036080	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0	0.2	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.3	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0	0.2	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0052595	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0	0.1	GO:0098782	mechanically-gated potassium channel activity(GO:0098782)
0.0	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.1	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0	1.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0	0.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.3	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0	0.0	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.3	GO:0019841	retinol binding(GO:0019841)
0.0	0.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.0	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	1.1	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.3	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	1.0	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.0	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0	0.1	GO:0016901	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	1.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.6	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	1.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	1.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi