Project

Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for MSX2

Z-value: 0.49

Motif logo

logo of

Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
MSX2
ENSG00000120149.7 MSX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX2hg19_v2_chr5_+_174151536_1741516100.255.5e-01Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_138453606 0.73 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
 PCDH18
 protocadherin 18
chr6_-_167040731 0.61 ENST00000265678.4
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_43045439 0.52 ENST00000253407.3
 C1QL1
 complement component 1, q subcomponent-like 1
chr1_-_232651312 0.52 ENST00000262861.4
 SIPA1L2
 signal-induced proliferation-associated 1 like 2
chr16_+_53133070 0.41 ENST00000565832.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr4_-_138453559 0.40 ENST00000511115.1
 PCDH18
 protocadherin 18
chr10_-_28571015 0.29 ENST00000375719.3
ENST00000375732.1
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr3_-_114866084 0.27 ENST00000357258.3
 ZBTB20
 zinc finger and BTB domain containing 20
chr7_+_134331550 0.21 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
 BPGM
 2,3-bisphosphoglycerate mutase
chr7_+_99717230 0.20 ENST00000262932.3
 CNPY4
 canopy FGF signaling regulator 4
chr8_-_12612962 0.18 ENST00000398246.3
 LONRF1
 LON peptidase N-terminal domain and ring finger 1
chr9_+_80912059 0.17 ENST00000347159.2
ENST00000376588.3
 PSAT1
 phosphoserine aminotransferase 1
chr22_+_46476192 0.17 ENST00000443490.1
 FLJ27365
 hsa-mir-4763
chr1_+_151735431 0.17 ENST00000321531.5
ENST00000315067.8
 OAZ3
 ornithine decarboxylase antizyme 3
chr7_+_100209979 0.17 ENST00000493970.1
ENST00000379527.2
 MOSPD3
 motile sperm domain containing 3
chr7_+_100209725 0.17 ENST00000223054.4
 MOSPD3
 motile sperm domain containing 3
chr6_+_25652432 0.16 ENST00000377961.2
 SCGN
 secretagogin, EF-hand calcium binding protein
chr10_+_85954377 0.16 ENST00000332904.3
ENST00000372117.3
 CDHR1
 cadherin-related family member 1
chr1_-_23694794 0.16 ENST00000374608.3
 ZNF436
 zinc finger protein 436
chrX_-_48931648 0.15 ENST00000376386.3
ENST00000376390.4
 PRAF2
 PRA1 domain family, member 2
chr11_+_33061543 0.15 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
 TCP11L1
 t-complex 11, testis-specific-like 1
chr7_+_100210133 0.15 ENST00000393950.2
ENST00000424091.2
 MOSPD3
 motile sperm domain containing 3
chr15_-_37393406 0.15 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
 MEIS2
 Meis homeobox 2
chr2_-_73460334 0.14 ENST00000258083.2
 PRADC1
 protease-associated domain containing 1
chr11_-_124981475 0.14 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
 TMEM218
 transmembrane protein 218
chr8_+_38831683 0.14 ENST00000302495.4
 HTRA4
 HtrA serine peptidase 4
chr1_+_152943122 0.12 ENST00000328051.2
 SPRR4
 small proline-rich protein 4
chr1_-_151762943 0.12 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
 TDRKH
 tudor and KH domain containing
chr1_+_244515930 0.12 ENST00000366537.1
ENST00000308105.4
 C1orf100
 chromosome 1 open reading frame 100
chr5_+_162864575 0.12 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
 CCNG1
 cyclin G1
chr14_-_51027838 0.11 ENST00000555216.1
 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
chr11_+_67250490 0.11 ENST00000528641.2
ENST00000279146.3
 AIP
 aryl hydrocarbon receptor interacting protein
chr12_+_54718904 0.11 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1
 coatomer protein complex, subunit zeta 1
chr22_+_17956618 0.11 ENST00000262608.8
 CECR2
 cat eye syndrome chromosome region, candidate 2
chr1_-_36916066 0.10 ENST00000315643.9
 OSCP1
 organic solute carrier partner 1
chr17_+_74261413 0.10 ENST00000587913.1
 UBALD2
 UBA-like domain containing 2
chr1_-_151965048 0.09 ENST00000368809.1
 S100A10
 S100 calcium binding protein A10
chr16_+_58783542 0.09 ENST00000500117.1
ENST00000565722.1
 RP11-410D17.2
 RP11-410D17.2
chr22_-_30960876 0.09 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
 GAL3ST1
 galactose-3-O-sulfotransferase 1
chr1_-_36916011 0.09 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
 OSCP1
 organic solute carrier partner 1
chr19_-_47137942 0.09 ENST00000300873.4
 GNG8
 guanine nucleotide binding protein (G protein), gamma 8
chr7_-_2883928 0.09 ENST00000275364.3
 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
chr1_-_36915880 0.09 ENST00000445843.3
 OSCP1
 organic solute carrier partner 1
chr20_+_56964169 0.08 ENST00000475243.1
 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
chr7_-_99717463 0.08 ENST00000437822.2
 TAF6
 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr3_-_141747950 0.08 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr3_-_164796269 0.08 ENST00000264382.3
 SI
 sucrase-isomaltase (alpha-glucosidase)
chrX_-_15332665 0.07 ENST00000537676.1
ENST00000344384.4
 ASB11
 ankyrin repeat and SOCS box containing 11
chr7_-_99716952 0.07 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
 TAF6
 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_-_151431647 0.07 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
 POGZ
 pogo transposable element with ZNF domain
chr2_-_55646957 0.07 ENST00000263630.8
 CCDC88A
 coiled-coil domain containing 88A
chr14_+_65381079 0.07 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
 CHURC1
FNTB
CHURC1-FNTB
 churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr2_-_55647057 0.07 ENST00000436346.1
 CCDC88A
 coiled-coil domain containing 88A
chr1_-_68698197 0.07 ENST00000370973.2
ENST00000370971.1
 WLS
 wntless Wnt ligand secretion mediator
chr1_+_202317815 0.07 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr12_-_95397442 0.06 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
 NDUFA12
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr10_-_99447024 0.06 ENST00000370626.3
 AVPI1
 arginine vasopressin-induced 1
chr4_+_71587669 0.06 ENST00000381006.3
ENST00000226328.4
 RUFY3
 RUN and FYVE domain containing 3
chr16_+_69345243 0.06 ENST00000254950.11
 VPS4A
 vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr18_-_48346298 0.06 ENST00000398439.3
 MRO
 maestro
chrX_+_77154935 0.06 ENST00000481445.1
 COX7B
 cytochrome c oxidase subunit VIIb
chr5_+_31532373 0.06 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
 C5orf22
 chromosome 5 open reading frame 22
chr9_-_4666421 0.05 ENST00000381895.5
 SPATA6L
 spermatogenesis associated 6-like
chr6_+_34204642 0.05 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
 HMGA1
 high mobility group AT-hook 1
chr2_+_150187020 0.05 ENST00000334166.4
 LYPD6
 LY6/PLAUR domain containing 6
chr8_+_9413410 0.05 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
 TNKS
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr4_-_109684120 0.05 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
 ETNPPL
 ethanolamine-phosphate phospho-lyase
chr5_+_95997918 0.05 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
 CAST
 calpastatin
chr11_-_13517565 0.05 ENST00000282091.1
ENST00000529816.1
 PTH
 parathyroid hormone
chr2_-_27603582 0.05 ENST00000323703.6
ENST00000436006.1
 ZNF513
 zinc finger protein 513
chr10_-_99205607 0.05 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
 EXOSC1
 exosome component 1
chr14_-_23504337 0.04 ENST00000361611.6
 PSMB5
 proteasome (prosome, macropain) subunit, beta type, 5
chr11_-_71823796 0.04 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
 ANAPC15
 anaphase promoting complex subunit 15
chr1_+_175036966 0.04 ENST00000239462.4
 TNN
 tenascin N
chr11_+_101918153 0.04 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
 C11orf70
 chromosome 11 open reading frame 70
chr1_-_151431909 0.04 ENST00000361398.3
ENST00000271715.2
 POGZ
 pogo transposable element with ZNF domain
chr15_+_41245160 0.04 ENST00000444189.2
ENST00000446533.3
 CHAC1
 ChaC, cation transport regulator homolog 1 (E. coli)
chr19_-_10121144 0.04 ENST00000264828.3
 COL5A3
 collagen, type V, alpha 3
chr14_-_23504432 0.04 ENST00000425762.2
 PSMB5
 proteasome (prosome, macropain) subunit, beta type, 5
chr2_+_172864490 0.04 ENST00000315796.4
 METAP1D
 methionyl aminopeptidase type 1D (mitochondrial)
chr18_+_5748793 0.04 ENST00000566533.1
ENST00000562452.2
 RP11-945C19.1
 RP11-945C19.1
chr7_+_48211048 0.04 ENST00000435803.1
 ABCA13
 ATP-binding cassette, sub-family A (ABC1), member 13
chr13_-_103389159 0.03 ENST00000322527.2
 CCDC168
 coiled-coil domain containing 168
chr11_-_121986923 0.03 ENST00000560104.1
 BLID
 BH3-like motif containing, cell death inducer
chr19_+_17378159 0.03 ENST00000598188.1
ENST00000359435.4
ENST00000599474.1
ENST00000599057.1
ENST00000601043.1
ENST00000447614.2
 BABAM1
 BRISC and BRCA1 A complex member 1
chr18_+_39535152 0.03 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
 PIK3C3
 phosphatidylinositol 3-kinase, catalytic subunit type 3
chr11_-_71823715 0.03 ENST00000545944.1
ENST00000502597.2
 ANAPC15
 anaphase promoting complex subunit 15
chr6_+_160183492 0.03 ENST00000541436.1
 ACAT2
 acetyl-CoA acetyltransferase 2
chr1_-_68698222 0.03 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS
 wntless Wnt ligand secretion mediator
chr19_+_17378278 0.03 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
 BABAM1
 BRISC and BRCA1 A complex member 1
chr3_+_186353756 0.03 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
 FETUB
 fetuin B
chr7_-_56174161 0.03 ENST00000395422.3
 CHCHD2
 coiled-coil-helix-coiled-coil-helix domain containing 2
chr10_-_72142345 0.03 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
 LRRC20
 leucine rich repeat containing 20
chr21_-_22175341 0.03 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
 LINC00320
 long intergenic non-protein coding RNA 320
chr3_-_48672859 0.03 ENST00000395550.2
ENST00000455886.2
ENST00000431739.1
ENST00000426599.1
ENST00000383733.3
ENST00000420764.2
ENST00000337000.8
 SLC26A6
 solute carrier family 26 (anion exchanger), member 6
chr5_+_140797296 0.03 ENST00000398594.2
 PCDHGB7
 protocadherin gamma subfamily B, 7
chr3_+_140396881 0.03 ENST00000286349.3
 TRIM42
 tripartite motif containing 42
chr1_-_228613026 0.03 ENST00000366696.1
 HIST3H3
 histone cluster 3, H3
chr17_-_9929581 0.02 ENST00000437099.2
ENST00000396115.2
 GAS7
 growth arrest-specific 7
chr5_+_95998070 0.02 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
 CAST
 calpastatin
chr5_+_140557371 0.02 ENST00000239444.2
 PCDHB8
 protocadherin beta 8
chr11_-_71823266 0.02 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
 ANAPC15
 anaphase promoting complex subunit 15
chr19_+_41869894 0.02 ENST00000413014.2
 TMEM91
 transmembrane protein 91
chr11_-_40315640 0.02 ENST00000278198.2
 LRRC4C
 leucine rich repeat containing 4C
chr15_+_80351910 0.02 ENST00000261749.6
ENST00000561060.1
 ZFAND6
 zinc finger, AN1-type domain 6
chr17_+_42264556 0.02 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
 TMUB2
 transmembrane and ubiquitin-like domain containing 2
chr10_-_105110831 0.02 ENST00000337211.4
 PCGF6
 polycomb group ring finger 6
chrX_+_70752945 0.02 ENST00000373701.3
 OGT
 O-linked N-acetylglucosamine (GlcNAc) transferase
chr7_+_100183927 0.02 ENST00000241071.6
ENST00000360609.2
 FBXO24
 F-box protein 24
chr19_-_46088068 0.01 ENST00000263275.4
ENST00000323060.3
 OPA3
 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr15_-_98417780 0.01 ENST00000503874.3
 LINC00923
 long intergenic non-protein coding RNA 923
chr17_-_10372875 0.01 ENST00000255381.2
 MYH4
 myosin, heavy chain 4, skeletal muscle
chr8_+_92261516 0.01 ENST00000276609.3
ENST00000309536.2
 SLC26A7
 solute carrier family 26 (anion exchanger), member 7
chrX_+_70752917 0.01 ENST00000373719.3
 OGT
 O-linked N-acetylglucosamine (GlcNAc) transferase
chr10_-_56561022 0.01 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
 PCDH15
 protocadherin-related 15
chr2_+_113829895 0.01 ENST00000393197.2
 IL1F10
 interleukin 1 family, member 10 (theta)
chr6_-_116833500 0.01 ENST00000356128.4
 TRAPPC3L
 trafficking protein particle complex 3-like
chr10_-_105110890 0.00 ENST00000369847.3
 PCGF6
 polycomb group ring finger 6
chr5_-_148758839 0.00 ENST00000261796.3
 IL17B
 interleukin 17B
chr17_+_74261277 0.00 ENST00000327490.6
 UBALD2
 UBA-like domain containing 2
chr2_-_98280383 0.00 ENST00000289228.5
 ACTR1B
 ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr19_+_42817527 0.00 ENST00000598766.1
 TMEM145
 transmembrane protein 145
chr11_+_17298255 0.00 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
 NUCB2
 nucleobindin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets