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Epithelial-Mesenchymal Transition, human (Scheel, 2011)
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Results for MYF6
Z-value: 0.90
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Transcription factors associated with MYF6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYF6 | hg19_v2_chr12_+_81101277_81101321 | -0.07 | 8.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYF6
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_57045228 | 1.77 |
ENST00000371250.3 |
PPAP2B |
phosphatidic acid phosphatase type 2B |
| chr16_+_53133070 | 1.29 |
ENST00000565832.1 |
CHD9 |
chromodomain helicase DNA binding protein 9 |
| chr8_-_23712312 | 1.12 |
ENST00000290271.2 |
STC1 |
stanniocalcin 1 |
| chr7_+_100199800 | 1.02 |
ENST00000223061.5 |
PCOLCE |
procollagen C-endopeptidase enhancer |
| chr2_+_148778570 | 0.96 |
ENST00000407073.1 |
MBD5 |
methyl-CpG binding domain protein 5 |
| chr3_+_110790590 | 0.95 |
ENST00000485303.1 |
PVRL3 |
poliovirus receptor-related 3 |
| chr2_+_11295624 | 0.81 |
ENST00000402361.1 ENST00000428481.1 |
PQLC3 |
PQ loop repeat containing 3 |
| chr17_-_39306054 | 0.79 |
ENST00000343246.4 |
KRTAP4-5 |
keratin associated protein 4-5 |
| chr1_-_236228417 | 0.76 |
ENST00000264187.6 |
NID1 |
nidogen 1 |
| chr1_-_236228403 | 0.74 |
ENST00000366595.3 |
NID1 |
nidogen 1 |
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.3 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.1 | 1.7 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.1 | 1.5 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 1.4 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 1.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.2 | 1.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.0 | 1.0 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.9 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 0.9 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.0 | 0.8 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 1.7 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.0 | 1.5 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 1.4 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 1.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 1.0 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 1.0 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 0.8 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.7 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.2 | 1.5 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.8 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 0.7 | GO:0004308 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 0.0 | 0.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.1 | 0.6 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.6 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.1 | 0.6 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.9 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.0 | 0.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.4 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.3 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.0 | 0.3 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.2 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.7 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 0.9 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.7 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.0 | 0.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |